{
    "ULRYiIsd": {
        "id": "ULRYiIsd",
        "title": "Multiuser scheduling on the downlink of an LTE cellular system",
        "abstract": "The challenge of scheduling user transmissions on the downlink of a long-term evolution (LTE) cellular communication system is addressed. In particular, a novel optimalmultiuser scheduler is proposed. Numerical results show that the system performance improves with increasing correlation among OFDMA subcarriers. It is found that only a limited amount of feedback information is needed to achieve relatively good performance. A suboptimal reduced-complexity scheduler is also proposed and shown to provide good performance. The suboptimal scheme is especially attractive when the number of users is large, in which case the complexity of the optimal scheme is high.",
        "keywords": [],
        "authors": [
            {
                "name": "Raymond Kwan",
                "org": "Centre for Wireless Network Design, University of Bedfordshire, Luton, UK"
            },
            {
                "name": "Cyril Leung",
                "org": "Department of Electrical and Computer Engineering, University of British Columbia, Vancouver, Canada"
            },
            {
                "name": "Jie Zhang",
                "org": "Centre for Wireless Network Design, University of Bedfordshire, Luton, UK"
            }
        ],
        "venue": "J. Electrical and Computer Engineering",
        "year": 2008
    },
    "NriBPtBs": {
        "id": "NriBPtBs",
        "title": "A Particle Swarm Optimization Algorithm for Multiuser Scheduling in HSDPA",
        "abstract": "This paper briefs the problem of optimal multiuser scheduling in HSDPA. The modulation and coding schemes (MCSs), numbers of multicodes and power levels for all users are jointly optimized at each scheduling period, given that only limited Channel Quality Indicator (CQI) information, as specified in the HSDPA standard [1], is fed back to the BS. An integer programming model is proposed in order to provide a globally optimal solution to the multiuser scheduling problem. Due to the complexity of the globally optimal method, a swarm intelligence approach, namely particle swarm optimization (PSO), is subsequently proposed. The experimentations suggest that it potentially provides a near-optimum performance with significantly reduced complexity.",
        "keywords": [
            "coding scheme",
            "particle swarm optimization",
            "scheduling period",
            "optimal multiuser scheduling",
            "optimal solution",
            "multiuser scheduling problem",
            "optimal method",
            "channel quality indicator",
            "multiuser scheduling",
            "swarm intelligence approach",
            "particle swarm optimization algorithm",
            "hsdpa standard",
            "global optimization",
            "swarm intelligence",
            "scheduling problem"
        ],
        "authors": [
            {
                "name": "Mehmet E. Aydin",
                "org": "University of Bedfordshire, CWIND, Luton, UK"
            },
            {
                "name": "Raymon Kwan",
                "org": "University of Bedfordshire, CWIND, Luton, UK"
            },
            {
                "name": "Cyril Leung",
                "org": "The University of British Columbia, Vancouver, Canada"
            },
            {
                "name": "Jie Zhang",
                "org": "University of Bedfordshire, CWIND, Luton, UK"
            }
        ],
        "venue": "ANTS Conference",
        "year": 2008
    },
    "68tgP1MY": {
        "id": "68tgP1MY",
        "title": "Multiuser Scheduling for High Speed Uplink Packet Access",
        "abstract": "",
        "keywords": [
            "access protocols",
            "multi-access systems",
            "radio networks",
            "radio spectrum management",
            "scheduling",
            "3GPP network",
            "discrete optimization problem",
            "high speed uplink packet access protocol",
            "multiuser scheduling",
            "radio resource allocation"
        ],
        "authors": [
            {
                "name": "Raymond Kwan",
                "org": ""
            },
            {
                "name": "Cyril Leung",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            }
        ],
        "venue": "VTC Spring",
        "year": 2008
    },
    "NpMkwoSE": {
        "id": "NpMkwoSE",
        "title": "On the Use of a Lower Frequency in Finite-Difference Simulations for Urban Radio Coverage",
        "abstract": "",
        "keywords": [
            "diffraction",
            "calibration",
            "finite difference",
            "predictive models",
            "attenuation",
            "computational modeling",
            "finite difference methods",
            "frequency",
            "finite difference time domain",
            "computer networks",
            "frequency response"
        ],
        "authors": [
            {
                "name": "Alvaro V. Rial",
                "org": ""
            },
            {
                "name": "Guillaume De La Roche",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            }
        ],
        "venue": "VTC Spring",
        "year": 2008
    },
    "q2skmFn5": {
        "id": "q2skmFn5",
        "title": "A Power Assignment Scheme for Improving Outage Probability in HSDPA",
        "abstract": "",
        "keywords": [
            "probability distribution",
            "wireless communication",
            "channel coding",
            "downlink",
            "statistical distributions",
            "signal to interference ratio",
            "quality of service",
            "throughput",
            "voice over ip"
        ],
        "authors": [
            {
                "name": "Raymond Kwan",
                "org": ""
            },
            {
                "name": "Cyril Leung",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            }
        ],
        "venue": "VTC Spring",
        "year": 2008
    },
    "Au6Gb1SZ": {
        "id": "Au6Gb1SZ",
        "title": "A GPU approach to FDTD for Radio Coverage Prediction",
        "abstract": "The benefits of using Finite-Difference alike methods for coverage prediction comprise highly accurate electromagnetic simulations that serve as a reliable input for wireless networks planning and optimization algorithms. These algorithms usually require several thousands of iterations in order to find the optimal network configuration, so to obtain results within reasonable computation times, the applied propagation models must be as fast as possible. In this study an implementation-oriented analysis on the suitability of using Graphics Processing Units (GPU) to perform Finite-Difference Time-Domain simulations is carried out. We believe that the recently released Compute Unified Device Architecture (CUDA) technology has opened the door for computational intensive algorithms such as FDTD to be considered for the first time as a precise and fast propagation model to predict radio coverage. I. INTRODUCTION With the very fast deployment of wireless networks during the last decades, the need for radio network planning tools that aid operators to design and optimize their wireless infras- tructure is rising. In order to increase the reliability of these tools, accurate radio wave propagation models are necessary. The currently used optimization tools make use of em- pirical or semi-empirical models (1) (2) due to its quick implementability and short running time. But these models suffer from a lack of precission in complex environments such as urban scenarios, where the different obstacles should be more accurately modeled. It is thus necessary to make use of deterministic models based on physical laws that try to compute the reflections, diffractions, transmissions and scattering on obstacles. Ray-tracing and geometric-like models (3) (4) have been proposed. They have shown to be very efficient, except in too severe environments, where too many reflections need to be computed, and where the diffraction phenomena, even with the Uniform Theory of Diffraction (UTD), are difficult to simulate. Another well known approach to compute radio wave propa- gation is the Finite-Difference Time-Domain (FDTD) model (5), which solves the Maxwell equations on a discrete grid. This method is attractive because all the reflections/diffractions are implicitly taken into account by its formulation. However, since FDTD tries to simulate an unbounded region in a size- restricted area, an Absorbing Boundary Condition (ABC) such as the Convolutional Perfectly Matched Layer (CPML) (6) must be used in order to avoid reflections on the border.",
        "keywords": [
            "finite difference time-domain analysis",
            "radio networks",
            "FDTD",
            "compute unified device architecture technology",
            "finite-difference time-domain simulations",
            "graphics processing units",
            "radio coverage prediction"
        ],
        "authors": [
            {
                "name": "Alvaro Valcarce",
                "org": "Centre for Wireless Network|University of Bedfordshire"
            },
            {
                "name": "Guillaume De La Roche",
                "org": "Centre for Wireless Network|University of Bedfordshire"
            },
            {
                "name": "Jie Zhang",
                "org": "Centre for Wireless Network|University of Bedfordshire"
            }
        ],
        "venue": "international conference on conceptual structures",
        "year": 2008
    },
    "SnSo8doI": {
        "id": "SnSo8doI",
        "title": "On statistical characterization of EESM effective SNR over frequency selective channels",
        "abstract": "A novel expression of the moment generating function (MGF) of the exponential effective SNR mapping (EESM) signal-to-noise ratio (SNR) over two correlated but not necessarily identically distributed Nakagami-m fading channels is presented. Based on the MGF, a novel expression for the average effective SNR is also presented. Numerical evaluation of these expressions shows that the proposed approach can be a useful and efficient analytical tool in analyzing the characteristics of EESM over correlated Nakagami-m fading channels.",
        "keywords": [
            "frequency selective channel",
            "exponential effective snr mapping",
            "nakagami channels",
            "correlated nakagami-m fading channel",
            "correlated fading",
            "statistical analysis",
            "average effective snr",
            "nakagami-m fading channels",
            "novel expression",
            "gamma distribution",
            "statistical characterization",
            "numerical evaluation",
            "frequency selective channels",
            "efficient analytical tool",
            "eesm effective snr",
            "nakagami-m fading channel",
            "signal-to-noise ratio",
            "moment generating function",
            "wireless communication",
            "fading",
            "correlation",
            "frequency division multiplexing",
            "ofdm",
            "signal to noise ratio",
            "signal generators",
            "ofdm modulation",
            "nakagami distribution",
            "random variables",
            "fading channel",
            "orthogonal frequency division multiplexing"
        ],
        "authors": [
            {
                "name": "Hui Song",
                "org": "Centre for Wireless Network Design, University of Bedfordshire, Luton, UK"
            },
            {
                "name": "Raymond Kwan",
                "org": "Centre for Wireless Network Design, University of Bedfordshire, Luton, UK"
            },
            {
                "name": "Jie Zhang",
                "org": "Centre for Wireless Network Design, University of Bedfordshire, Luton, UK"
            }
        ],
        "venue": "IEEE Transactions on Wireless Communications",
        "year": 2009
    },
    "gwHuskhP": {
        "id": "gwHuskhP",
        "title": "Proportional Fair Multiuser Scheduling in LTE",
        "abstract": "",
        "keywords": [
            "throughput",
            "downlink",
            "signal to noise ratio",
            "fading channel",
            "scheduling",
            "proportional fair",
            "ofdm modulation",
            "degradation",
            "scheduling algorithm",
            "communication system"
        ],
        "authors": [
            {
                "name": "Raymond Kwan",
                "org": ""
            },
            {
                "name": "Cyril Leung",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            }
        ],
        "venue": "IEEE Signal Process. Lett.",
        "year": 2009
    },
    "n9AZ7sbJ": {
        "id": "n9AZ7sbJ",
        "title": "Applying FDTD to the coverage prediction of WiMAX femtocells",
        "abstract": "Femtocells, or home base stations, are a potential future solution for operators to increase indoor coverage and reduce network cost. In a real WiMAX femtocell deployment in residential areas covered by WiMAX macrocells, interference is very likely to occur both in the streets and certain indoor regions. Propagation models that take into account both the outdoor and indoor channel characteristics are thus necessary for the purpose of WiMAX network planning in the presence of femtocells. In this paper, the finite-difference time-domain (FDTD) method is adapted for the computation of radiowave propagation predictions at WiMAX frequencies. This model is particularly suitable for the study of hybrid indoor/outdoor scenarios and thus well adapted for the case of WiMAX femtocells in residential environments. Two optimization methods are proposed for the reduction of the FDTD simulation time: the reduction of the simulation frequency for problem simplification and a parallel graphics processing units (GPUs) implementation. The calibration of the model is then thoroughly described. First, the calibration of the absorbing boundary condition, necessary for proper coverage predictions, is presented. Then a calibration of the material parameters that minimizes the error function between simulation and real measurements is proposed. Finally, some mobile WiMAX system-level simulations that make use of the presented propagation model are presented to illustrate the applicability of the model for the study of femto- to macrointerference.",
        "keywords": [
            "mobile wimax system-level simulation",
            "wimax network planning",
            "indoor coverage",
            "indoor channel characteristic",
            "real wimax femtocell deployment",
            "propagation model",
            "certain indoor region",
            "wimax femtocells",
            "coverage prediction",
            "wimax macrocells",
            "wimax frequency"
        ],
        "authors": [
            {
                "name": "Alvaro Valcarce",
                "org": "Centre for Wireless Network Design, University of Bedfordshire, Bedfordshire, UK"
            },
            {
                "name": "Guillaume De La Roche",
                "org": "Centre for Wireless Network Design, University of Bedfordshire, Bedfordshire, UK"
            },
            {
                "name": "Álpar Jüttner",
                "org": "Centre for Wireless Network Design, University of Bedfordshire, Bedfordshire, UK"
            },
            {
                "name": "David López-Pérez",
                "org": "Centre for Wireless Network Design, University of Bedfordshire, Bedfordshire, UK"
            },
            {
                "name": "Jie Zhang",
                "org": "Centre for Wireless Network Design, University of Bedfordshire, Bedfordshire, UK"
            }
        ],
        "venue": "EURASIP J. Wireless Comm. and Networking",
        "year": 2009
    },
    "HypmT0FD": {
        "id": "HypmT0FD",
        "title": "Resource allocation in an LTE cellular communication system",
        "abstract": "The problem of allocating resources for user transmissions on the downlink of a Long Term Evolution (LTE) cellular communication system is studied. A novel optimal multiuser scheduler is proposed and its performance is evaluated. Numerical results show that the system performance improves with increasing correlation among OFDMA sub-carriers. It is found that a limited amount of feedback information can provide a relatively good performance. A sub-optimal scheduler with a lower computational complexity is also proposed, and shown to provide good performance. The sub-optimal scheme is especially attractive when the number of users is large, as the complexity of the optimal scheme may be unacceptably high in many practical situations.",
        "keywords": [
            "optimal scheme",
            "resource allocation",
            "long term evolution",
            "system performance",
            "lte cellular communication system",
            "ofdma sub-carriers",
            "good performance",
            "lower computational complexity",
            "novel optimal multiuser scheduler",
            "cellular communication system",
            "sub-optimal scheme",
            "sub-optimal scheduler",
            "cellular networks",
            "ofdm modulation",
            "downlink",
            "feedback",
            "computational complexity",
            "communication system",
            "signal to noise ratio",
            "throughput",
            "interference",
            "ofdm",
            "resource management",
            "scheduling",
            "dsl"
        ],
        "authors": [
            {
                "name": "Raymond Kwan",
                "org": "Centre for Wireless Network Designs, University of Bedfordshire, Luton, UK"
            },
            {
                "name": "Cyril Leung",
                "org": "Dept. of Electrical & Computer Engineering, The University of British Columbia, B.C., Canada"
            },
            {
                "name": "Jie Zhang",
                "org": "Centre for Wireless Network Designs, University of Bedfordshire, Luton, UK"
            }
        ],
        "venue": "ICC",
        "year": 2009
    },
    "M5DaRKR7": {
        "id": "M5DaRKR7",
        "title": "Multiuser Scheduling in HSDPA with Particle Swarm Optimization",
        "abstract": "In this paper, a mathematical model of multiuser scheduling problem in HSDPA is developed to use in optimization process. A more realistic imperfect channel state information (CSI) feedback, which is required for this problem, in the form of a finite set of Channel Quality Indicator (CQI) values is assumed, as specified in the HSDPA standard [1]. A global optimal approach and a particle swarm optimization approach are used to solve the problem. Simulation results indicate that the performances of the two approaches are very close even though the complexity of the particle swarm optimization approach is much lower.",
        "keywords": [
            "particle swarm optimization",
            "multiuser scheduling problem",
            "mathematical model",
            "simulation result",
            "channel quality indicator",
            "multiuser scheduling",
            "finite set",
            "realistic imperfect channel state",
            "hsdpa standard",
            "optimization process",
            "global optimal approach",
            "particle swarm optimization approach",
            "global optimization",
            "channel state information",
            "scheduling problem"
        ],
        "authors": [
            {
                "name": "Mehmet E. Aydin",
                "org": "University of Bedfordshire, CWIND, Luton, UK"
            },
            {
                "name": "Raymond Kwan",
                "org": "University of Bedfordshire, CWIND, Luton, UK"
            },
            {
                "name": "Cyril Leung",
                "org": "The University of British Columbia, Vancouver, Canada V6T 1Z4"
            },
            {
                "name": "Jie Zhang",
                "org": "University of Bedfordshire, CWIND, Luton, UK"
            }
        ],
        "venue": "EvoWorkshops",
        "year": 2009
    },
    "p4cRlEBC": {
        "id": "p4cRlEBC",
        "title": "A new approach to solve angular dispersion of discrete ray launching for urban scenarios",
        "abstract": "",
        "keywords": [
            "antennas",
            "wave propagation",
            "point to point",
            "beam tracing",
            "data mining",
            "ray tracing",
            "distributed computing"
        ],
        "authors": [
            {
                "name": "zhihua lai",
                "org": "university of bedfordshire"
            },
            {
                "name": "nik bessis",
                "org": "university of bedfordshire"
            },
            {
                "name": "guillaume de la roche",
                "org": "university of bedfordshire"
            },
            {
                "name": "pierre kuonen",
                "org": "university of colorado hospital"
            },
            {
                "name": "jie zhang",
                "org": "university of bedfordshire"
            },
            {
                "name": "gordon j clapworthy",
                "org": "university of bedfordshire"
            }
        ],
        "venue": "",
        "year": 2009
    },
    "X8W0iJiA": {
        "id": "X8W0iJiA",
        "title": "Access control mechanisms for femtocells",
        "abstract": "Femtocells are a solution that helps to reduce the capital and operational expenditure of a mobile network while enhancing system coverage and capacity. However, the avoidance of interference is still an issue that needs to be addressed to successfully deploy a femtocell tier over existing macrocell networks. Moreover, interference is strongly dependent on the type of access control, which decides if a given user can or cannot connect to the femtocell. In this article the existing access methods for femtocells together with their benefits and drawbacks are explained. A description of the business model and technical impact of access methods in femto/macro networks is also provided. Finally, the need for hybrid access methods and several models are presented.",
        "keywords": [
            "mobile network",
            "hybrid access method",
            "operational expenditure",
            "access method",
            "macrocell network",
            "access control",
            "macro network",
            "business model",
            "access control mechanism",
            "femtocell tier",
            "existing access method",
            "interference",
            "time frequency analysis",
            "downlink",
            "quality of service",
            "throughput",
            "ofdm",
            "femtocells"
        ],
        "authors": [
            {
                "name": "Guillaume De La Roche",
                "org": "University of Bedfordshire"
            },
            {
                "name": "Alvaro Valcarce",
                "org": "University of Bedfordshire"
            },
            {
                "name": "David López-Pérez",
                "org": "University of Bedfordshire"
            },
            {
                "name": "Jie Zhang",
                "org": "University of Bedfordshire"
            }
        ],
        "venue": "IEEE Communications Magazine",
        "year": 2009
    },
    "sy3SNRSV": {
        "id": "sy3SNRSV",
        "title": "Dynamic Frequency Planning Versus Frequency Reuse Schemes in OFDMA Networks",
        "abstract": "In order to avoid inter-cell interference, OFDMA networks are flexible in terms of radio resource management techniques, supporting different frequency reuse schemes (FRSs), which in turn, may decrease inter-cell interference and increase network performance. However, because most of them are based on fix patterns, these FRSs cannot cope with the uneven distri - bution and dynamic behavior of the traffic throughout the day . This work introduces a novel approach to the frequency as- signment problem called Dynamic Frequency Planning (DFP) tai- lored to OFDMA networks. The proposed approach dynamically adapts the radio frequency parameters to the environment taking the user and channel conditions into account. Moreover, a variant of DFP, called vertical DFP, based on the fractional frequency reuse schemes (FFRSs) concept is proposed. In comparison to the traditional FRSs, these techniques notably mitigate inter-cell interference and enhance network performance.",
        "keywords": [
            "quality of service",
            "throughput",
            "bandwidth",
            "interference",
            "ofdm modulation",
            "planning",
            "ofdm",
            "radio resource management",
            "resource management",
            "silicon",
            "network performance",
            "wireless communication",
            "wireless networks",
            "wimax",
            "radio frequency",
            "signal to noise ratio",
            "frequency allocation"
        ],
        "authors": [
            {
                "name": "David López-Pérez",
                "org": ""
            },
            {
                "name": "Alpár Jüttner",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            }
        ],
        "venue": "VTC Spring",
        "year": 2009
    },
    "PTQFGNYp": {
        "id": "PTQFGNYp",
        "title": "Two-dimensional radio resource allocation algorithms with contiguity constraint for IEEE 802.16e systems.",
        "abstract": "Adaptive multi-user resource allocation is one of the key features towards high speed wireless network based on Orthogonal Frequency Division Multiplexing Access (OFDMA). According to IEEE 802.16e (WiMAX) standard radio, resource allocation problem has to be performed on a two-dimensional space (frequency and time) with the constraint that each trans- mitted burst should occupy a contiguous portion of the frame. The paper introduces two different strategies and it investigates the advantages, drawbacks and challenges of the radio resource allocation procedure in two dimensions. I. INTRODUCTION",
        "keywords": [
            "cost function",
            "ofdm modulation",
            "ofdm",
            "wimax",
            "fading",
            "two dimensions",
            "resource management",
            "throughput",
            "wireless network",
            "resource allocation"
        ],
        "authors": [
            {
                "name": "Lorenzo Galati Giordano",
                "org": "instituto politecnico nacional"
            },
            {
                "name": "David López-Pérez",
                "org": "university of bedfordshire"
            },
            {
                "name": "Luca Reggiani",
                "org": "instituto politecnico nacional"
            },
            {
                "name": "Laura Dossi",
                "org": "instituto politecnico nacional"
            },
            {
                "name": "Alpár Jüttner",
                "org": "university of bedfordshire"
            },
            {
                "name": "Jie Zhang",
                "org": "university of bedfordshire"
            }
        ],
        "venue": "PIMRC",
        "year": 2009
    },
    "1ehUiiPX": {
        "id": "1ehUiiPX",
        "title": "Limited access to OFDMA femtocells",
        "abstract": "Femtocells are a promising solution for the provision of high indoor coverage and capacity. Furthermore, OFDMA- based femtocells have proven to be highly versatile when dealing with cross-layer co-channel interference thanks to the allocation of frequency subchannels. However, concerns still exist related to the impact of the different access methods to femtocells in an overlayed network. Femtocells based on a Closed Subscribers Group, where only device owners are allowed connectivity intro- duce severe interference to macrocell users. On the other hand, Open Access femtocells where any user can connect, does not bring many advantages to the femtocell owner. In this paper, an intermediate access method based on a limited access is proposed. The performance of the model is evaluated throughout system- level simulations and it is shown that limited access contributes to seriously reduce cross-layer interference while guaranteeing a minimum performance to the femtocell subscribers. I. INTRODUCTION",
        "keywords": [
            "throughput",
            "overlay network",
            "ofdm",
            "interference",
            "data models",
            "ofdm modulation",
            "femtocells",
            "channel allocation",
            "co channel interference",
            "access method",
            "wimax",
            "frequency allocation"
        ],
        "authors": [
            {
                "name": "Alvaro Valcarce",
                "org": "Guillaume De La Roche|Centre for Wireless Network|University of Bedfordshire"
            },
            {
                "name": "David López-Pérez",
                "org": "Guillaume De La Roche|Centre for Wireless Network|University of Bedfordshire"
            },
            {
                "name": "Guillaume de la Roche",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            }
        ],
        "venue": "PIMRC",
        "year": 2009
    },
    "qyI61Dm9": {
        "id": "qyI61Dm9",
        "title": "On the Average Output SNR of Exponential Effective SNR Mapping over Nakagami-m Fading Channels",
        "abstract": "A novel expression of the moment generating function (MGF) of the exponential effective SNR mapping (EESM) signal-to-noise ratio (SNR) over two correlated but not necessarily identically distributed Nakagami-m fading channels is presented. Based on the MGF, a novel expression for the average effective SNR is also presented. Numerical evaluation of these expressions shows that the proposed approach can be a useful and efficient analytical tool in analyzing the characteristics of EESM over correlated Nakagami-m fading channels.",
        "keywords": [
            "fading channels",
            "method of moments",
            "exponential effective snr mapping",
            "correlated nakagami-m fading channels",
            "exponential distribution",
            "signal-to-noise ratio",
            "moment generating function",
            "probability density function",
            "fading channel",
            "random variables",
            "fading",
            "ofdm",
            "correlation",
            "signal to noise ratio"
        ],
        "authors": [
            {
                "name": "Hui Song",
                "org": ""
            },
            {
                "name": "Raymond Kwan",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            }
        ],
        "venue": "VTC Fall",
        "year": 2009
    },
    "sp4nUq3a": {
        "id": "sp4nUq3a",
        "title": "A Performance Evaluation of a Grid-Enabled Object-Oriented Parallel Outdoor Ray Launching for Wireless Network Coverage Prediction",
        "abstract": "The use of parallel technologies to solve complex scientific problems has gained increased popularity. The ray optical methods are deterministic propagation approaches that are based on geometrically searching paths between emitter and receivers. They offer higher accuracy than empirical models, but suffer from slow calculations on exhausted rays that have to be searched. In this paper, an object-oriented scheme based on POP-C++ for parallel objects to accelerate outdoor ray launching is described. Performance evaluation is presented to show that this parallel scheme is promising in outdoor wireless propagation modeling. The possibility of running this model in the distributed grid environment is also discussed. Results have shown the great potential of using such a parallel model to predict accurate outdoor wireless propagation scenarios within a short time.",
        "keywords": [
            "parallel model",
            "parallel technology",
            "outdoor ray launching",
            "wireless network coverage prediction",
            "ray launching",
            "deterministic propagation approach",
            "propagation modeling",
            "accurate outdoor wireless",
            "performance evaluation",
            "parallel scheme",
            "grid-enabled object-oriented parallel outdoor",
            "parallel object",
            "outdoor wireless",
            "propagation scenario",
            "data mining",
            "empirical model",
            "wireless network",
            "mobile communication",
            "object oriented",
            "wireless communication",
            "radio propagation"
        ],
        "authors": [
            {
                "name": "Zhihua Lai",
                "org": ""
            },
            {
                "name": "Nik Bessis",
                "org": ""
            },
            {
                "name": "Pierre Kuonen",
                "org": ""
            },
            {
                "name": "Guillaume de la Roche",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Gordon Clapworthy",
                "org": ""
            }
        ],
        "venue": "ICWMC '09 Proceedings of the 2009 Fifth International Conference on Wireless and Mobile Communications",
        "year": 2009
    },
    "RBsGil6L": {
        "id": "RBsGil6L",
        "title": "A two-step method for the optimization of antenna azimuth/tilt and frequency planning in OFDMA multihop networks",
        "abstract": "During the network planning process, it is very important to identify the key network design factors and define how to take them into account to achieve optimally performing networks. The introduction of Relay Stations (RSs) in OFDMA-based networks will bring numerous advantages such as coverage extension and capacity enhancement due to the deployment of new cells and the reduction of distance between transmitter and receiver. However, the use of RSs will also bring new challenges to the network designers, for example, interference management in multihop communications. This work establishes the fundamentals of a new approach that will adapt the tilt, azimuth, and frequency assignment in OFDMA networks - in the form of subchannel planning - according to the changing conditions of the traffic and the radio channel in a novel two-step process for network design. An example of deployment is presented in this paper.",
        "keywords": [
            "ofdma network",
            "novel two-step process",
            "network design",
            "network designer",
            "new challenge",
            "new approach",
            "network planning process",
            "key network design factor",
            "new cell",
            "two-step method",
            "ofdma-based network",
            "ofdma multihop network",
            "antenna azimuth",
            "frequency planning",
            "network planning",
            "azimuth",
            "optimization"
        ],
        "authors": [
            {
                "name": "Fernando Gordejuela-Sánchez",
                "org": "University of Bedfordshire, Luton, UK"
            },
            {
                "name": "David López-Pérez",
                "org": "University of Bedfordshire, Luton, UK"
            },
            {
                "name": "Jie Zhang",
                "org": "University of Bedfordshire, Luton, UK"
            }
        ],
        "venue": "IWCMC",
        "year": 2009
    },
    "46oaD2x8": {
        "id": "46oaD2x8",
        "title": "An Intelligent Ray Launching for urban prediction",
        "abstract": "",
        "keywords": [
            "probability density function",
            "acceleration",
            "predictive models",
            "data mining",
            "computational modeling",
            "empirical model"
        ],
        "authors": [
            {
                "name": "zhihua lai",
                "org": "university of bedfordshire"
            },
            {
                "name": "nil bessis",
                "org": "university of bedfordshire"
            },
            {
                "name": "guillaume de laroche",
                "org": "university of bedfordshire"
            },
            {
                "name": "hui song",
                "org": "university of bedfordshire"
            },
            {
                "name": "jie zhang",
                "org": "university of bedfordshire"
            },
            {
                "name": "gordon j clapworthy",
                "org": "university of bedfordshire"
            }
        ],
        "venue": "",
        "year": 2009
    },
    "fwCLaveG": {
        "id": "fwCLaveG",
        "title": "Predicting Small-Scale Fading Distributions with Finite-Difference Methods in Indoor-to-Outdoor Scenarios",
        "abstract": "",
        "keywords": [
            "fading",
            "finite difference method",
            "usability",
            "testing",
            "electromagnetic fields",
            "multipath propagation",
            "finite difference methods",
            "cellular network",
            "computational electromagnetics",
            "wimax",
            "predictive models",
            "cellular networks",
            "finite difference",
            "femtocells"
        ],
        "authors": [
            {
                "name": "Alvaro Valcarce",
                "org": ""
            },
            {
                "name": "David López-Pérez",
                "org": ""
            },
            {
                "name": "Guillaume de la Roche",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            }
        ],
        "venue": "VTC Spring",
        "year": 2009
    },
    "SF256LC4": {
        "id": "SF256LC4",
        "title": "Dynamic system-level simulation of dynamic frequency planing for real time services in WiMAX networks",
        "abstract": "This paper introduces a dynamic system-level simulator for WIMAX (Wireless Interoperability for Microwave Access) networks that can be used to analyze the behavior of several network procedures. Moreover, the performance of a new approach to the frequency assignment problem, called DFP (Dynamic Frequency Planning), is studied using this simulation platform. DFP is able to run from a few times a day down to a frame by frame basis, balancing the radio resources between neighbouring BSs (Base Stations) and providing interference mitigation. We demonstrate the efficacy of DFP compared to off-the-shelf FRSs (Frequency Reuse Schemes) in terms of average network capacity and delay.",
        "keywords": [
            "base stations",
            "network procedure",
            "wimax network",
            "dynamic frequency",
            "dynamic frequency planning",
            "real time service",
            "frequency reuse schemes",
            "dynamic system-level simulation",
            "microwave access",
            "frequency assignment problem",
            "wireless interoperability",
            "frame basis",
            "average network capacity",
            "dynamic system-level simulator",
            "wimax",
            "real time",
            "access network",
            "dynamic system",
            "base station"
        ],
        "authors": [
            {
                "name": "David López-Pérez",
                "org": "Bedfordshire University, Luton, UK"
            },
            {
                "name": "Alpár Jüttner",
                "org": "Bedfordshire University, Luton, UK"
            },
            {
                "name": "Jie Zhang",
                "org": "Bedfordshire University, Luton, UK"
            }
        ],
        "venue": "IWCMC",
        "year": 2009
    },
    "X8SpVxQo": {
        "id": "X8SpVxQo",
        "title": "OFDMA femtocells: A self-organizing approach for frequency assignment",
        "abstract": "",
        "keywords": [
            "resource management",
            "mathematical model",
            "channel allocation",
            "femtocells",
            "ofdm modulation",
            "self organization",
            "broadcasting",
            "interference",
            "signal to noise ratio",
            "ofdm"
        ],
        "authors": [
            {
                "name": "David López-Pérez",
                "org": ""
            },
            {
                "name": "Ákos Ladányi",
                "org": ""
            },
            {
                "name": "Alpár Jüttner",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            }
        ],
        "venue": "PIMRC",
        "year": 2009
    },
    "gMM8Wd7L": {
        "id": "gMM8Wd7L",
        "title": "OFDMA Femtocells: Intracell Handover for Interference and Handover Mitigation in Two-Tier Networks.",
        "abstract": "",
        "keywords": [
            "switches",
            "dsl",
            "femtocell",
            "electromagnetic interference",
            "throughput",
            "bandwidth",
            "wireless networks",
            "channel allocation",
            "signal to noise ratio",
            "argon",
            "femtocells",
            "interference"
        ],
        "authors": [
            {
                "name": "David López-Pérez",
                "org": "university of bedfordshire"
            },
            {
                "name": "Ákos Ladányi",
                "org": ""
            },
            {
                "name": "Alpár Jüttner",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            }
        ],
        "venue": "WCNC",
        "year": 2010
    },
    "mGth1rEJ": {
        "id": "mGth1rEJ",
        "title": "Femtocells: Technologies and Deployment",
        "abstract": "This book provides an in-depth guide to femtocell technologies In this book, the authors provide a comprehensive and organized explanation of the femtocell concepts, architecture, air interface technologies, and challenging issues arising from the deployment of femtocells, such as interference, mobility management and self-organization. The book details a system level simulation based methodology addressing the key concerns of femtocell deployment such as interference between femto and macrocells, and the performance of both femto and macrocell layers. In addition, key research topics in interference modeling and mitigation, mobility management and Self-Organizing Network (SON) are highlighted. The authors also introduce HNB/HeNB standardization in 3GPP.. Furthermore, access methods (closed, open and hybrid), applications, timing synchronization, health issues, business models and security are discussed. The authors also provide a comparison between femtocells and other indoor coverage techniques such as picocells, repeaters, distributed antenna systems and radio over fiber. Lastly, both CDMA and OFDMA based femtocells are covered. Key Features: Provides a comprehensive reference on femtocells and related topics Offers the latest research results on femtocells based on simulation and measurements Gives an overview of indoor coverage techniques such as picocells, repeaters, distributed antenna systems, radio over fiber and femtocells Includes chapters on femtocell access network architecture, air interface technologies (GSM, UMTS, HSPA, WiMAX and LTE), femtocell simulation, interference analysis and mitigation in femto/macrocell networks, mobility management in femto/macrocell networks, femtocell self-organization and other key challenges such as timing synchronization and security faced by femtocell deployment Points to over 240 references from 3GPP, The Femto Forum, journals and conference proceedings This book will be an invaluable guide for RF engineers from operators, R&D engineers from femtocells hardware manufacturers, employees from regulatory bodies, radio network planners, academics and researchers from universities and research organizations. Students undertaking wireless communications courses will also find this book insightful.",
        "keywords": [
            "femtocell access network architecture",
            "timing synchronization",
            "mobility management",
            "femtocell concept",
            "macrocell network",
            "indoor coverage technique",
            "femtocell deployment points",
            "air interface technology",
            "femtocell self-organization",
            "antenna system"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Guillaume de la Roche",
                "org": ""
            }
        ],
        "venue": "Femtocells: Technologies and Deployment",
        "year": 2010
    },
    "cb1cllOZ": {
        "id": "cb1cllOZ",
        "title": "Empirical Indoor-to-Outdoor Propagation Model for Residential Areas at 0.9–3.5 GHz",
        "abstract": "This paper introduces analytical expressions for the modeling of path-loss and shadow fading in residential indoor- to-outdoor scenarios. The formulas have been calibrated using channel power measurements at the radio frequencies of common cellular systems and are thus suitable for channel modeling in femtocell networks. The expressions presented here can be used as a simple propagation model in system-level simulators, as well as for comparison with other models. Furthermore, its compact formulation simplifies its use for theoretical studies of two-tier networks, while its empirical nature strengthens its validity. Index Terms—indoor, outdoor, empirical, propagation model, femtocell",
        "keywords": [
            "cellular radio",
            "indoor radio",
            "radiofrequency measurement",
            "simulation",
            "cellular systems",
            "channel modeling",
            "channel power measurements",
            "empirical indoor-to-outdoor propagation",
            "femtocell networks",
            "frequency 0.9 GHz to 3.5 GHz",
            "path loss",
            "radio frequencies",
            "residential areas",
            "residential indoor-to-outdoor scenarios",
            "shadow fading",
            "system-level simulators",
            "Empirical",
            "femtocell",
            "indoor",
            "outdoor",
            "propagation model"
        ],
        "authors": [
            {
                "name": "Alvaro Valcarce",
                "org": "Inst. for Res. on Applicable Comput. (IRAC), Univ. of Bedfordshire, Luton, UK|c|"
            },
            {
                "name": "Jie Zhang",
                "org": ""
            }
        ],
        "venue": "Antennas and Wireless Propagation Letters, IEEE",
        "year": 2010
    },
    "IC2ormzs": {
        "id": "IC2ormzs",
        "title": "On SNR Statistics Involving EESM-Based Frequency Selective Feedbacks",
        "abstract": "",
        "keywords": [
            "modulation",
            "feedback",
            "fading",
            "ofdm",
            "fading channel",
            "signal to noise ratio",
            "correlation",
            "wireless communication",
            "statistics"
        ],
        "authors": [
            {
                "name": "Hui Song",
                "org": ""
            },
            {
                "name": "Raymond Kwan",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            }
        ],
        "venue": "VTC Fall",
        "year": 2010
    },
    "NIWmn7Qj": {
        "id": "NIWmn7Qj",
        "title": "A novel indoor localization scheme",
        "abstract": "Ultra-wideband (UWB) receivers can resolve individual multipath components (MPCs), due to the signal occupied a large bandwidths, so they are capable of accurately estimating the time of flight of the signal. To realize high-accuracy indoor localization, a novel UWB locating scheme through estimating the round trip time (RTT) of UWB signal is proposed. Each reference station (RS) transmits the baseband pulse modulated UWB signals. The signals are received by the user terminals (UT) and sent back to the original RS using a different carrier frequency. We can easily calculate the position of the UT by detecting the time gap between the feedback signal and the origin signal. Meanwhile, the multi-path detection algorithm for RTT estimation is presented and the localization performance of the proposed scheme is tested under IEEE 802.15.4a channel models. Experiments demonstrate that the proposed scheme can realize high accuracy localization with an error around the centimeter level.",
        "keywords": [
            "global positioning system",
            "signal estimation",
            "multipath detection",
            "reference station",
            "time of flight estimation",
            "uwb",
            "ieee 802.15.4a",
            "round trip time",
            "multipath channels",
            "ultra wideband communication",
            "user terminals",
            "indoor localization scheme",
            "ultra wideband receivers",
            "channel models",
            "baseband pulse modulation",
            "pulse modulation",
            "signal detection",
            "indoor radio",
            "interference",
            "copper",
            "antennas",
            "ultra wideband",
            "time of flight",
            "ofdm",
            "transmitters",
            "throughput"
        ],
        "authors": [
            {
                "name": "HaiLiang Xiong",
                "org": "University of Bedfordshire(^ University of Bedfordshire),Luton,United Kingdom"
            },
            {
                "name": "Hui Song",
                "org": "University of Bedfordshire(^ University of Bedfordshire),Luton,United Kingdom"
            },
            {
                "name": "Zhihua Lai",
                "org": "University of Bedfordshire(^ University of Bedfordshire),Luton,United Kingdom"
            },
            {
                "name": "Jie Zhang",
                "org": "University of Bedfordshire(^ University of Bedfordshire),Luton,United Kingdom"
            },
            {
                "name": "Kechu Yi",
                "org": "Xidian University(Xidian University,Xidian Univ.),Xi An,China"
            }
        ],
        "venue": "Communication Technology",
        "year": 2010
    },
    "V9ZQ2Lxb": {
        "id": "V9ZQ2Lxb",
        "title": "General results on SNR statistics involving EESM-based frequency selective feedbacks",
        "abstract": "Novel methods of obtaining the moment generating function (MGF) and moments of the exponential effective SNR mapping (EESM) signal-to-noise ratio (SNR) over N jointly distributed fading channels are presented. Based on these methods, novel explicit expressions of the MGF and moments over arbitrary number of correlated Nakagami-m fading channels are proposed. Numerical evaluation of these expressions shows that the proposed approach can be a useful and efficient analytical tool in characterizing the statistics of EESM over correlated Nakagami-m fading channels.",
        "keywords": [
            "eesm-based frequency selective feedbacks",
            "n jointly distributed fading channels",
            "exponential effective snr mapping",
            "novel method",
            "selective feedbacks",
            "correlated nakagami-m fading channel",
            "correlated fading",
            "statistical analysis",
            "general result",
            "fading channels",
            "arbitrary number",
            "numerical analysis",
            "gamma distribution",
            "novel explicit expression",
            "snr statistics",
            "nakagami-m fading channels",
            "snr statistic",
            "numerical evaluation",
            "eesm-based frequency",
            "efficient analytical tool",
            "correlated nakagami-m fading channels",
            "signal-to-noise ratio",
            "moment generating function",
            "ofdm modulation",
            "statistics",
            "encoding",
            "statistical distributions",
            "signal to noise ratio",
            "correlation",
            "random variables",
            "fading channel",
            "fading",
            "quality of service",
            "frequency",
            "ofdm",
            "feedback",
            "wireless communication"
        ],
        "authors": [
            {
                "name": "Hui Song",
                "org": "Centre for Wireless Network Design, University of Bedfordshire"
            },
            {
                "name": "Raymond Kwan",
                "org": "Centre for Wireless Network Design, University of Bedfordshire"
            },
            {
                "name": "Jie Zhang",
                "org": "Centre for Wireless Network Design, University of Bedfordshire"
            }
        ],
        "venue": "IEEE Transactions on Wireless Communications",
        "year": 2010
    },
    "OJG2Qgmo": {
        "id": "OJG2Qgmo",
        "title": "On the use of an Intelligent Ray Launching for indoor scenarios",
        "abstract": "Indoor propagation models attract much interest these days because of their importance in the applications of 3G/4G network planning and optimisation. The accuracy and running speed directly affects the practical use of such models. This paper extends a discrete ray launching model IRLA (Intelligent Ray Launching Algorithm) to indoor scenarios. A typical office room will be selected to validate this model. The efficiency and suitability of IRLA for indoor scenarios will be investigated and comparison with two referenced indoor models are given. The comparisons show that the modified IRLA for indoor scenarios obtains high accuracy within a reasonable time scale. It is promising because it is uniquely efficient on computation of rays, which outperforms most of the propagation models.",
        "keywords": [
            "mathematical model",
            "solid modeling",
            "frequency",
            "pervasive computing",
            "accuracy",
            "diffraction",
            "acceleration",
            "attenuation",
            "predictive models",
            "ubiquitous computing",
            "computational modeling"
        ],
        "authors": [
            {
                "name": "zhihua lai",
                "org": "university of bedfordshire"
            },
            {
                "name": "nik bessis",
                "org": "university of bedfordshire"
            },
            {
                "name": "guillaume de la roche",
                "org": "university of bedfordshire"
            },
            {
                "name": "pierre kuonen",
                "org": "university of colorado hospital"
            },
            {
                "name": "jie zhang",
                "org": "university of bedfordshire"
            },
            {
                "name": "gordon j clapworthy",
                "org": "university of bedfordshire"
            }
        ],
        "venue": "Antennas and Propagation",
        "year": 2010
    },
    "lTElE9Qb": {
        "id": "lTElE9Qb",
        "title": "Intracell handover for interference and handover mitigation in OFDMA two-tier macrocell-femtocell networks",
        "abstract": "There are two main access policies (open and closed) to Femtocell Access Points (FAPs), being closed access the customers favorite. However, closed access is the root cause of crosstier interference in cochannel deployments of two-tier networks (i.e., macrocells and femtocells). Further, the effect of this problem is remarkably serious in the downlink of outdoor users not subscribed to any femtocell. Open access has been considered as a potential solution to this problem. However, this increases signaling in the network due to the elevated number of HandOvers (HOs) that mobile users have to perform. Therefore, this paper proposes an interference avoidance technique based on the use of Intracell HandOvers (IHOs) in Orthogonal Frequency Division Multiple Access (OFDMA) femtocells. It is shown that a proper combination of IHO and power control techniques reduces the outage probability for nonsubscribers compared with that of closed and open access. In addition, the impact of several network parameters such as the femtocell penetration is also considered in the analysis.",
        "keywords": [
            "femtocell penetration",
            "open access",
            "ofdma two-tier macrocell-femtocell network",
            "network parameter",
            "closed access",
            "femtocell access points",
            "main access policy",
            "crosstier interference",
            "intracell handover",
            "two-tier network",
            "interference avoidance technique",
            "handover mitigation",
            "intracell handovers"
        ],
        "authors": [
            {
                "name": "David López-Pérez",
                "org": "Centre for Wireless Network Design, University of Bedfordshire, Luton, UK"
            },
            {
                "name": "Alvaro Valcarce",
                "org": "Centre for Wireless Network Design, University of Bedfordshire, Luton, UK"
            },
            {
                "name": "Ákos Ladányi",
                "org": "Centre for Wireless Network Design, University of Bedfordshire, Luton, UK"
            },
            {
                "name": "Guillaume de la Roche",
                "org": "Centre for Wireless Network Design, University of Bedfordshire, Luton, UK"
            },
            {
                "name": "Jie Zhang",
                "org": "Centre for Wireless Network Design, University of Bedfordshire, Luton, UK"
            }
        ],
        "venue": "EURASIP J. Wireless Comm. and Networking",
        "year": 2010
    },
    "f6egWK3F": {
        "id": "f6egWK3F",
        "title": "Approximations of EESM Effective SNR Distribution",
        "abstract": "The Probability Density Function (PDF) or Cumulative Distribution Function (CDF) of the effective Signal to Noise Ratio (SNR) is an important statistical characterization in the performance analysis of an Orthogonal Frequency Division Multiple Access (OFDMA) system using Exponential Effective SNR Mapping (EESM). However, the exact closed form of PDF is extremely difficult to obtain. A general approximation method known as Moment Matching Approximating (MMA) is used to approximate the distribution of effective SNR by a simple expression. In this paper, the approximation by Gaussian, Generalized Extreme Value (GEV) and Pearson distribution are studied. Results show that Gaussian approximation is very useful when the number of sub-carriers is sufficiently large. Both GEV and Pearson approximation are accurate enough in approximating the distribution of effective SNR in a general case.",
        "keywords": [
            "channel feedback",
            "pearson distribution",
            "generalized extreme value (gev) distribution",
            "gaussian approximation",
            "orthogonal frequency division multiple access",
            "probability density function",
            "ofdm modulation",
            "signal to noise ratio",
            "gaussian distribution",
            "moment matching approximating",
            "frequency division multiple access",
            "exponential effective snr mapping (eesm)",
            "orthogonal frequency division multiple access (ofdma)",
            "pearson system",
            "long term evolution (lte)",
            "long term evolution",
            "cumulative distribution function",
            "generalized extreme value",
            "exponential effective snr mapping",
            "moment matching approximating (mma)",
            "random variable",
            "wimax",
            "bandwidth",
            "random variables",
            "fading"
        ],
        "authors": [
            {
                "name": "Hui Song",
                "org": ""
            },
            {
                "name": "Raymond Kwan",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            }
        ],
        "venue": "IEEE Transactions on Communications",
        "year": 2011
    },
    "JRhCHXPp": {
        "id": "JRhCHXPp",
        "title": "The Development of a Parallel Ray Launching Algorithm for Wireless Network Planning",
        "abstract": "",
        "keywords": [
            "wireless network"
        ],
        "authors": [
            {
                "name": "Zhihua Lai",
                "org": ""
            },
            {
                "name": "Nik Bessis",
                "org": ""
            },
            {
                "name": "Guillaume de la Roche",
                "org": ""
            },
            {
                "name": "Pierre Kuonen",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Gordon Clapworthy",
                "org": ""
            }
        ],
        "venue": "International Journal of Distributed Systems and Technologies",
        "year": 2011
    },
    "PMVoa8yC": {
        "id": "PMVoa8yC",
        "title": "Hybrid Model for Indoor-to-Outdoor Femtocell Radio Coverage Prediction.",
        "abstract": "",
        "keywords": [
            "finite difference method",
            "predictive models",
            "finite difference time domain",
            "finite difference methods",
            "mathematical model",
            "empirical model",
            "computer model",
            "prediction model",
            "computational modeling",
            "path loss",
            "accuracy",
            "indexing terms"
        ],
        "authors": [
            {
                "name": "Guillaume de la Roche",
                "org": ""
            },
            {
                "name": "Alvaro Valcarce Rial",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            }
        ],
        "venue": "VTC Spring",
        "year": 2011
    },
    "BLDGDoVs": {
        "id": "BLDGDoVs",
        "title": "Enhanced Inter-Cell Interference Coordination Challenges in Heterogeneous Networks",
        "abstract": "",
        "keywords": [
            "lte",
            "interference",
            "cellular network",
            "network topology",
            "wireless network",
            "ofdm",
            "femtocells",
            "heterogeneous network",
            "cellular networks"
        ],
        "authors": [
            {
                "name": "David López-Pérez",
                "org": "king s college london"
            },
            {
                "name": "Ismail Güvenç",
                "org": "ntt docomo"
            },
            {
                "name": "Guillaume de la Roche",
                "org": "university of bedfordshire"
            },
            {
                "name": "Marios Kountouris",
                "org": "supelec"
            },
            {
                "name": "Tony Q. S. Quek",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": "university of sheffield"
            }
        ],
        "venue": "IEEE Wireless Commun.",
        "year": 2011
    },
    "1BmZRNL3": {
        "id": "1BmZRNL3",
        "title": "Distributed resource allocation for femtocell interference coordination via power minimisation.",
        "abstract": "",
        "keywords": [
            "assignment problem",
            "self organization",
            "ofdm modulation",
            "scheduling",
            "frequency allocation"
        ],
        "authors": [
            {
                "name": "Ákos Ladányi",
                "org": "university of bedfordshire"
            },
            {
                "name": "David López-Pérez",
                "org": "king s college london"
            },
            {
                "name": "Alpár Jüttner",
                "org": "eotvos lorand university"
            },
            {
                "name": "Xiaoli Chu",
                "org": "king s college london"
            },
            {
                "name": "Jie Zhang",
                "org": "university of bedfordshire"
            }
        ],
        "venue": "global communications conference",
        "year": 2011
    },
    "mID2i1Zh": {
        "id": "mID2i1Zh",
        "title": "Multiuser Scheduling on the LTE Downlink with Simulated Annealing.",
        "abstract": "",
        "keywords": [
            "interference",
            "signal to noise ratio",
            "scheduling",
            "simulated annealing",
            "ofdm",
            "communication system"
        ],
        "authors": [
            {
                "name": "Mehmet Emin Aydin",
                "org": ""
            },
            {
                "name": "Raymond Kwan",
                "org": ""
            },
            {
                "name": "Joyce Y. Wu",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            }
        ],
        "venue": "VTC Spring",
        "year": 2011
    },
    "iYaOvczw": {
        "id": "iYaOvczw",
        "title": "Optimization method for the joint allocation of modulation schemes, coding rates, resource blocks and power in self-organizing LTE networks.",
        "abstract": "",
        "keywords": [
            "optimization problem",
            "decomposition",
            "self organization",
            "interference",
            "modulation",
            "ofdm",
            "throughput",
            "optimization",
            "decomposition method",
            "encoding",
            "resource management",
            "resource manager"
        ],
        "authors": [
            {
                "name": "David López-Pérez",
                "org": ""
            },
            {
                "name": "Ákos Ladányi",
                "org": ""
            },
            {
                "name": "Alpár Jüttner",
                "org": ""
            },
            {
                "name": "Hervé Rivano",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            }
        ],
        "venue": "INFOCOM",
        "year": 2011
    },
    "O12UECer": {
        "id": "O12UECer",
        "title": "The Development of a Parallel Ray Launching Algorithm for Wireless Network Planning",
        "abstract": "Propagation modeling has attracted much interest because it plays an important role in wireless network planning and optimization. Deterministic approaches such as ray tracing and ray launching have been investigated, however, due to the running time constraint, these approaches are still not widely used. In previous work, an intelligent ray launching algorithm, namely IRLA, has been proposed. The IRLA has proven to be a fast and accurate algorithm and adapts to wireless network planning well. This article focuses on the development of a parallel ray launching algorithm based on the IRLA. Simulations are implemented, and evaluated performance shows that the parallelization greatly shortens the running time. The COST231 Munich scenario is adopted to verify algorithm behavior in real world environments, and observed results show a 5 times increased speedup upon a 16-processor cluster. In addition, the parallelization algorithm can be easily extended to larger scenarios with sufficient physical resources.",
        "keywords": [
            "Parallel Ray Launching Algorithm",
            "ray launching",
            "wireless network",
            "parallel ray",
            "intelligent ray",
            "wireless network planning",
            "16-processor cluster",
            "Wireless Network Planning",
            "algorithm behavior",
            "time constraint",
            "parallelization algorithm",
            "accurate algorithm"
        ],
        "authors": [
            {
                "name": "Nik Bessis",
                "org": "University of Bedfordshire, UK"
            },
            {
                "name": "Gordon J. Clapworthy",
                "org": "University of Bedfordshire, UK"
            },
            {
                "name": "Zhihua Lai",
                "org": "University of Bedfordshire, UK"
            },
            {
                "name": "Guillaume De La Roche",
                "org": "University of Applied Science of Western Switzerland, Switzerland"
            },
            {
                "name": "Pierre Kuonen",
                "org": "University of Applied Science of Western Switzerland, Switzerland"
            },
            {
                "name": "Jie Zhang",
                "org": "University of Bedfordshire, UK"
            }
        ],
        "venue": "IJDST",
        "year": 2011
    },
    "rf9Ho4pq": {
        "id": "rf9Ho4pq",
        "title": "Analytical Approximations of EESM Effective SNR Distribution Using Pearson System",
        "abstract": "Link adaptation is an important technique in achieving good system spectral efficiency. However, due to the effect of frequency selective fading, the SNRs of adjacent sub-carriers in an OFDMA system can potentially be different. To provide a reasonable signalling overhead, the smallest unit of channel quality feedback is represented in terms of a group of sub-carrier SNRs, or effective SNR for short. The knowledge of the PDF or CDF of the effective SNR can be very useful in performance analysis of systems involving frequency selective feedback. However, closed-form expressions of these statistical quantities are very difficult to obtained. In this paper, we propose to approximate these quantities using the method of Pearson system. Numerical results show that the proposed approximation is very accurate.",
        "keywords": [
            "radio links",
            "eesm effective snr distribution",
            "signalling overhead",
            "ofdma system",
            "approximation theory",
            "frequency selective fading",
            "orthogonal frequency division multiple access",
            "probability density function",
            "fading channels",
            "signal to noise ratio",
            "spectral analysis",
            "higher order statistics",
            "wireless channels",
            "frequency division multiple access",
            "link adaptation",
            "pearson system",
            "channel quality feedback",
            "analytical approximation",
            "cumulative distribution function",
            "exponential effective snr mapping",
            "adjacent sub-carrier",
            "spectral efficiency",
            "ofdm",
            "fading",
            "indexing terms",
            "wireless communication"
        ],
        "authors": [
            {
                "name": "Hui Song",
                "org": ""
            },
            {
                "name": "Raymond Kwan",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            }
        ],
        "venue": "VTC Spring",
        "year": 2011
    },
    "wD5EL92C": {
        "id": "wD5EL92C",
        "title": "ENHANCED INTERCELL INTERFERENCE COORDINATION CHALLENGES IN HETEROGENEOUS NETWORKS H ET N ETS : A N EW P ARADIGM F OR I NCREASING C ELLULAR C APACITY A ND C OVERAGE",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "david lopezperez",
                "org": ""
            },
            {
                "name": "i smail guvenc",
                "org": ""
            },
            {
                "name": "guillaume de la roche",
                "org": ""
            },
            {
                "name": "marios kountouris",
                "org": ""
            },
            {
                "name": "tony q s quek",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2011
    },
    "jABTTfVF": {
        "id": "jABTTfVF",
        "title": "Dynamic Downlink Frequency and Power Allocation in OFDMA Cellular Networks.",
        "abstract": "",
        "keywords": [
            "lte",
            "interference",
            "resource management",
            "dynamic scheduling",
            "throughput",
            "ofdm",
            "capacity",
            "ofdm modulation"
        ],
        "authors": [
            {
                "name": "David López-Pérez",
                "org": ""
            },
            {
                "name": "Xiaoli Chu",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            }
        ],
        "venue": "IEEE Transactions on Communications",
        "year": 2012
    },
    "b2AMXysA": {
        "id": "b2AMXysA",
        "title": "Small Cell Deployments: Recent Advances and Research Challenges",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Zubin Bharucha",
                "org": ""
            },
            {
                "name": "Emilio Calvanese Strinati",
                "org": ""
            },
            {
                "name": "Jiming Chen",
                "org": ""
            },
            {
                "name": "Xiaoli Chu",
                "org": ""
            },
            {
                "name": "Afef Feki",
                "org": ""
            },
            {
                "name": "Antonio De Domenico",
                "org": ""
            },
            {
                "name": "Ana Galindo-Serrano",
                "org": ""
            },
            {
                "name": "Weisi Guo",
                "org": ""
            },
            {
                "name": "Raymond Kwan",
                "org": ""
            },
            {
                "name": "Jimin Liu",
                "org": ""
            },
            {
                "name": "David López-Pérez",
                "org": ""
            },
            {
                "name": "Massod Maqbool",
                "org": ""
            },
            {
                "name": "Ying Peng",
                "org": ""
            },
            {
                "name": "Samir Perlaza",
                "org": ""
            },
            {
                "name": "Guillaume de la Roche",
                "org": ""
            },
            {
                "name": "Serkan Uygungelen",
                "org": ""
            },
            {
                "name": "Alvaro Valcarce Rial",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            }
        ],
        "venue": "CoRR",
        "year": 2012
    },
    "ihgt2Vwv": {
        "id": "ihgt2Vwv",
        "title": "User data traffic analysis for 3G cellular networks",
        "abstract": "In this paper, an analysis of 3G network user data traffic is presented. With the increasing demands for high data rate and energy-efficient cellular service, it is important to understand how cellular user data traffic changes over time and in space. We provide statistical modelling of time-varying throughput per cell and the distribution of instantaneous throughput per cell over different cells based on throughput measurements from a real-world large-scale urban cellular network. Based on our inspection of the large set of cellular data traffic measurements, user data traffics on weekday and weekend are analyzed separately. Our proposed statistical models can generate network traffic data that are very close to the measured traffic and can be used in simulations of large-scale urban-area mobile networks.",
        "keywords": [
            "3g mobile communication",
            "cellular radio",
            "energy conservation",
            "statistical analysis",
            "telecommunication traffic",
            "3g cellular networks",
            "cellular data traffic measurements",
            "energy-efficient cellular service",
            "large-scale urban-area mobile networks",
            "network traffic data",
            "real-world large-scale urban cellular network",
            "statistical modelling",
            "statistical models",
            "throughput measurements",
            "time-varying throughput",
            "user data traffic analysis",
            "3g",
            "throughput",
            "user data traffic"
        ],
        "authors": [
            {
                "name": "Nan, E.",
                "org": "Dept. of Electron. & Electr. Eng., Univ. of Sheffield, Sheffield, UK|c|"
            },
            {
                "name": "Xiaoli Chu",
                "org": ""
            },
            {
                "name": "Weisi Guo",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            }
        ],
        "venue": "Communications and Networking in China",
        "year": 2013
    },
    "T6BHiU5g": {
        "id": "T6BHiU5g",
        "title": "A hybrid swarm intelligence algorithm for multiuser scheduling in HSDPA",
        "abstract": "Multiuser scheduling is an important aspect in the performance optimization of a wireless network since it allows multiple users to access a shared channel efficiently by exploiting multiuser diversity. To perform efficient scheduling, channel state information (CSI) for users is required, and is obtained via their respective feedback channels. In this paper, a more realistic imperfect CSI feedback, in the form of a finite set of Channel Quality Indicator (CQI) values, is assumed as specified in the HSDPA standard. A mathematical model of the problem is developed for use in the optimization process. A hybrid heuristic approach based on particle swarm optimization and simulated annealing is used to solve the problem. Simulation results indicate that the hybrid approach outperforms individual implementations of both simulated annealing and particle swarm optimization.",
        "keywords": [
            "particle swarm optimization",
            "hybrid swarm intelligence algorithm",
            "efficient scheduling",
            "multiuser scheduling",
            "realistic imperfect csi feedback",
            "simulated annealing",
            "hybrid approach",
            "channel state information",
            "performance optimization",
            "optimization process",
            "hybrid heuristic approach",
            "hsdpa",
            "resource allocation",
            "wireless networks"
        ],
        "authors": [
            {
                "name": "Mehmet E. Aydin",
                "org": "Department of Computer Science and Technology, University of Bedfordshire, Luton, LU1 3JU, UK"
            },
            {
                "name": "Raymond Kwan",
                "org": "Institute for Research in Applicable Computing, University of Bedfordshire, Luton, LU1 3JU, UK"
            },
            {
                "name": "Cyril Leung",
                "org": "Electrical and Computer Engineering, The University of British Columbia, Vancouver, BC V6T 1Z4, Canada"
            },
            {
                "name": "Carsten Maple",
                "org": "Institute for Research in Applicable Computing, University of Bedfordshire, Luton, LU1 3JU, UK"
            },
            {
                "name": "Jie Zhang",
                "org": "Department of Electronic and Electrical Engineering, University of Sheffield, Sheffield, S1 3JD, UK"
            }
        ],
        "venue": "Appl. Soft Comput.",
        "year": 2013
    },
    "X4YU7B2R": {
        "id": "X4YU7B2R",
        "title": "Automated small-cell deployment for heterogeneous cellular networks",
        "abstract": "Optimizing the cellular network's cell locations is one of the most fundamental problems of network design. The general objective is to provide the desired QoS with the minimum system cost. In order to meet a growing appetite for mobile data services, heterogeneous networks have been proposed as a cost- and energy-efficient method of improving local spectral efficiency. While unarticulated cell deployments can lead to localized improvements, there is a significant risk posed to network-wide performance due to the additional interference. The first part of the article focuses on state-of-the-art modelling and radio planning methods based on stochastic geometry and Monte Carlo simulations, and the emerging automatic deployment prediction technique for low-power nodes, or LPNs, in heterogeneous networks. The technique advises an LPN where it should be deployed, given certain knowledge of the network. The second part of the article focuses on algorithms that utilize interference and physical environment knowledge to assist LPN deployment. The proposed techniques can not only improve network performance, but also reduce radio planning complexity, capital expenditure, and energy consumption of the cellular network. The theoretical work is supported by numerical results from system-level simulations that employ real cellular network data and physical environments.",
        "keywords": [
            "heterogeneous cellular networks",
            "stochastic geometry",
            "cellular radio",
            "monte carlo simulations",
            "automated small-cell deployment",
            "quality of service",
            "radio planning methods",
            "mobile data services",
            "radio planning complexity",
            "cell locations",
            "qos",
            "local spectral efficiency",
            "monte carlo methods",
            "telecommunication network planning",
            "capital expenditure",
            "cell deployments",
            "interference (signal)",
            "network design",
            "mathematical model",
            "cellular networks",
            "signal to noise ratio",
            "network architecture",
            "interference",
            "stochastic processes"
        ],
        "authors": [
            {
                "name": "Weisi Guo",
                "org": ""
            },
            {
                "name": "Siyi Wang",
                "org": ""
            },
            {
                "name": "Xiaoli Chu",
                "org": ""
            },
            {
                "name": "Jiming Chen",
                "org": ""
            },
            {
                "name": "Hui Song",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            }
        ],
        "venue": "Communications Magazine, IEEE",
        "year": 2013
    },
    "BLzQtCLa": {
        "id": "BLzQtCLa",
        "title": "Resource Allocation in LTE-LAA and WiFi Coexistence: A Joint Contention Window Optimization Scheme.",
        "abstract": "Licensed-assisted access (LAA) is a promising technology to meet the exponential increase of traffic demand by exploiting the 5GHz unlicensed spectrum. However, without proper coexistence schemes, the performance of WiFi in coexistence with LAA will be degraded significantly. Equipped with listen-before-talk (LBT) schemes, LAA applies a channel access mechanism similar to distributed coordination function (DCF) in WiFi, which is not optimal in terms of spectrum efficiency. In this paper, we propose an joint optimization scheme to find the optimal combination of WiFi and LAA contention windows (CWs) that maximizes LAA throughput, while guarantees WiFi throughput above a predefined threshold. The accuracy and efficiency of the proposed scheme is evaluated by comparing with the exhaustive search: almost the same combination of CWs are achieved with much lower complexity by using the proposed scheme than the exhaustive search. Numeric results show that the proposed adaptive scheme is more effective in dense scenario, where high system (up to 40%) and LAA throughput gain (up to 100%) are achieved. The trade-off between LAA (system) throughput and WiFi throughput is also revealed.",
        "keywords": "",
        "authors": [
            {
                "name": "Yuan Gao",
                "org": "University of Sheffield"
            },
            {
                "name": "Bolin Chen",
                "org": "University of Sheffield"
            },
            {
                "name": "Xiaoli Chu",
                "org": "University of Sheffield"
            },
            {
                "name": "Jie Zhang",
                "org": "University of Sheffield"
            }
        ],
        "venue": "GLOBECOM",
        "year": 2017
    },
    "6JVUDnHP": {
        "id": "6JVUDnHP",
        "title": "The Analysis of Indoor Wireless Communications by a Blockage Model in Ultra-Dense Networks.",
        "abstract": "In indoor environments, the performance of ultra-dense cellular networks is significantly affected by blockages, especially for ultra-high frequencies. However, previous works either ignore or simplify such effects for analysing the networks. On the basis of stochastic geometry, this paper proposes a mathematically tractable approach to analyse ultra-dense networks in indoors, which considers both the effects of wall blockages and the distance-based path loss. The effects of wall blockages are firstly investigated by modelling the walls as a Boolean scheme of straight lines on a finite plane. Then a path loss model incorporating both the blockage-based and distance-based path loss is applied to analyse the performance of indoor networks. Finally, the analytical result is validated by comparing it with Monte Carlo simulations. The simulation results also show that the optimum transmitter density is finite for indoor ultra-dense networks with blockages, although the coverage probability benefits from the increase of transmitter density.",
        "keywords": "",
        "authors": [
            {
                "name": "Hui Zheng",
                "org": ""
            },
            {
                "name": "Jiliang Zhang",
                "org": ""
            },
            {
                "name": "Haonan Hu",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            }
        ],
        "venue": "VTC-Fall",
        "year": 2018
    },
    "QZ678JzI": {
        "id": "QZ678JzI",
        "title": "Effect of controlling irrigation on yield & quality of high-gluten wheat",
        "abstract": "The yield and quality of high-gluten wheat under the condition of controlling irrigation in different phase and with different times were studied.The results showed that the winter water can improve formation of wheat colony,but water is deficient in late period,yield will be low;irrigation in jointing phase can improve forming spike and increasing grains;with irrigation in grouting phase the yield will be low.In term of different irrigation stages,irrigation in jointing has the highest yield and the highest water use efficiency(WUE) Compared to irrigations in winter and grouting,the yield increases by 13.78% and 72.26%,respectively,and WUE increases by 10.29% and 47.06%,respectively.As the irrigation times increases,the yield will be higher,but the WUE will be lower.Watering in Grouting reduces the quality of high-gluten wheat.In view of yield,WUE and quality,irrigations in winter and in jointing are the best way for high-gluten wheat production.",
        "keywords": [
            "controlling flooding",
            "quality",
            "water use efficiency",
            "high-gluten wheat"
        ],
        "authors": [
            {
                "name": "WANG Yu-hong",
                "org": "Luoyang dry-land farming experiment base of Chinese academy of agricultural science,Luoyang,Henan ,China"
            },
            {
                "name": "YAO Yu-qing",
                "org": "Luoyang dry-land farming experiment base of Chinese academy of agricultural science,Luoyang,Henan ,China"
            },
            {
                "name": "LI Jun-hong",
                "org": "Luoyang dry-land farming experiment base of Chinese academy of agricultural science,Luoyang,Henan ,China"
            },
            {
                "name": "Zhang Jie",
                "org": "Luoyang dry-land farming experiment base of Chinese academy of agricultural science,Luoyang,Henan ,China"
            },
            {
                "name": "WANG Cong-hui",
                "org": "Luoyang dry-land farming experiment base of Chinese academy of agricultural science,Luoyang,Henan ,China"
            },
            {
                "name": "Ding Zhi-qiang",
                "org": "Luoyang dry-land farming experiment base of Chinese academy of agricultural science,Luoyang,Henan ,China"
            }
        ],
        "venue": "Agricultural Research in the Arid Areas",
        "year": 2006
    },
    "Qc8Mi5ot": {
        "id": "Qc8Mi5ot",
        "title": "Change of SMBC and SMBN under Conservation Tillage on Sloping Dryland",
        "abstract": "In order to study the change of the SOC's,Nitrogen's,SMBC's and SMBN's contents in soil,a experiment on the long-term locating field plots was performed smoothly on the semi-humid areas of the west of the Henan province.The results suggested that organic carbon in soil and nitrogen in soil are both increased under the sub-soiling tillage and no-tillage.Comparing with the other tillage patterns,the sub-soiling tillage have a highest SOC contents in soil,that is 6.79 g/kg,13.82% improved comparing to the traditional tillage.Nitrogen contents in soil under no-tillage have a highest contents among the above tillage patterns that is 0.797 g/kg,10.42% improved comparing to the traditional tillage.SOC and nitrogen is decreasing with soil layer being deepened.In the 0~20 cm soil layer under the sub-soiling tillage and no-tillage,SMBC and SMBN contents have been 79.3%,19.9% and 17.92%,8.13% improved comparing to the traditional tillage,and then the phenomenon of the bacterial enrichment was occurred under the low sloping soil.The positive co-relation distinguishedly was appeared between the SMBC and nitrogen in soil,SMBN,SMBC,and SMBN can be considered as the biological indexes to estimate the quality of the soil,for which have a distinguished relation.Hence,the subsoiling tillage and no-tillage have perfect future in appliance.",
        "keywords": [
            "conservation tillage",
            "soil microbial biomass carbon(SMBC)",
            "sloping field",
            "soil microbial biomass nitrogen(SMBN)"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Luoyang Academy of Agricultural Sciences,Luoyang,Henan "
            },
            {
                "name": "YAO Yu-qing",
                "org": "Luoyang Academy of Agricultural Sciences,Luoyang,Henan "
            },
            {
                "name": "JIN Ke",
                "org": "Institute of Agricultural Resources and Regional Planning,CAAS,Beijing "
            },
            {
                "name": "Lü Jun-jie",
                "org": "Luoyang Academy of Agricultural Sciences,Luoyang,Henan "
            },
            {
                "name": "WANG Cong-hui",
                "org": "Luoyang Academy of Agricultural Sciences,Luoyang,Henan "
            },
            {
                "name": "WANG Yu-hong",
                "org": "Luoyang Academy of Agricultural Sciences,Luoyang,Henan "
            },
            {
                "name": "LI Jun-hong",
                "org": "Luoyang Academy of Agricultural Sciences,Luoyang,Henan "
            },
            {
                "name": "DING Zhi-qiang",
                "org": "Luoyang Academy of Agricultural Sciences,Luoyang,Henan "
            }
        ],
        "venue": "Journal of Soil and Water Conservation",
        "year": 2007
    },
    "QnAaQz3A": {
        "id": "QnAaQz3A",
        "title": "Effects of Different Tillages on Soil Organic Carbon,Soil Microbial Biomass Carbon and Water Use Efficiency in the Slopping Field of Arid Areas",
        "abstract": "The effects of different tillages on the soil organic carbon(SOC),Soil microbial Biomass Carbon (SMBC) and Water Use Efficiency (WUE) in long-term locating field plots has been investigated in the slopping field of the semi-humid arid areas ,the west of Henan Province. The results showed as following the treatments with subsoiling tillage and no-till increased the SOC contents,especially in cultivated herizon,The most increase in SOC content was 6.79g kg-1 in subsoiling treatment. Comparing with conventional tillage,the SOC contents in subsoiling mulching and no-tillage increased by 13.82% and 11.58%.,but reduced tillage decreased by 1.38%. The average SOC contents in 0~60cm of the subsoiling and no-tillage increased by 14.08% and 5.41% respectively,but reduced tillage reduced by 1.12%.The deeper the layer was,the lower the SOC content did. The order of contents of SMBC was: no-tillage > subsoiling > conventional tillage >reduced tillage The rates of SMBC/SOC in reduced tillage,no-tillage,subsoiling and conventional tillage were 1.91%,3.11%,2.04% and 1.93% respectively. The no-tillage mulch and subsoiling mulch had higher productivity (10.22% and 9.26%) and WUE.",
        "keywords": [
            "Water Use Efficiency",
            "Conservational tillage",
            "Sloping field",
            "Soil organic carbon(SOC)",
            "Soil microbial Biomass Carbon (SMBC)"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "1.Luoyang Institute of Agricultural Sciences Luoyang,Henna ,"
            },
            {
                "name": "YAO Yu-qing",
                "org": "1.Luoyang Institute of Agricultural Sciences Luoyang,Henna ,"
            },
            {
                "name": "LV Jun-jie",
                "org": "1.Luoyang Institute of Agricultural Sciences Luoyang,Henna ,"
            },
            {
                "name": "WANG Yu-hong",
                "org": "1.Luoyang Institute of Agricultural Sciences Luoyang,Henna ,"
            },
            {
                "name": "JIN Ke",
                "org": "2.Institute of Agricultural Resources and Regional Planning,CAAS,Beijing, "
            },
            {
                "name": "WANG Cong-hui",
                "org": "1.Luoyang Institute of Agricultural Sciences Luoyang,Henna ,"
            },
            {
                "name": "HU Bo-wen",
                "org": "3.Beiguan Region of Agricultural Committee in Anyang,Anyang,Henan "
            },
            {
                "name": "LI Jun-hong",
                "org": "1.Luoyang Institute of Agricultural Sciences Luoyang,Henna ,"
            },
            {
                "name": "DING Zhi-qiang",
                "org": "1.Luoyang Institute of Agricultural Sciences Luoyang,Henna ,"
            }
        ],
        "venue": "Chinese Journal of Soil Science",
        "year": 2007
    },
    "l7YjecYJ": {
        "id": "l7YjecYJ",
        "title": "Effects of Different Conservation Tillage Practices on Winter Wheat Growth and Water Use Efficiency",
        "abstract": "With long-term experiments,this paper studied the effects of different conservational tillage practices on dryland winter wheat for two years.The results showed that the four kinds of conservational tillage and straw returningback-to-field technique improved wheat yield from 2.66% to 6.65% than conventional tillage with various extent,increased yield.Maize(zero-till)-wheat(zero-till) treatment was the best which enhanced yield significantly.Yield analysis indicated that the conservational tillage patterns gained high production by more grains per spike and 1000 gains weight.They produced less biomass in early growth stage to reduce soil water consumpion to save more soil water for grain filling.",
        "keywords": [
            "conservational tillage",
            "winter wheat",
            "application effect"
        ],
        "authors": [
            {
                "name": "YAO Yu-qing",
                "org": "Luoyang Academy of Agricultural Sciences,Luoyang ,China"
            },
            {
                "name": "WANG Yu-hong",
                "org": "Luoyang Academy of Agricultural Sciences,Luoyang ,China"
            },
            {
                "name": "LI Jun-hong",
                "org": "Luoyang Academy of Agricultural Sciences,Luoyang ,China"
            },
            {
                "name": "DING Zhi-qiang",
                "org": "Luoyang Academy of Agricultural Sciences,Luoyang ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Luoyang Academy of Agricultural Sciences,Luoyang ,China"
            }
        ],
        "venue": "System Sciences and Comprehensive Studies in Agriculture",
        "year": 2008
    },
    "Uc42Wk2K": {
        "id": "Uc42Wk2K",
        "title": "Effects of different mulching methods on winter wheat the growth on West of Henan dry-land",
        "abstract": "This paper analyzed effect of mulching on the growth of winter wheat and the soil water dynamics with plastic film,straw mulching and black liquid film.The results indicated that the significant effect of the plastic film on yield factors in these film,increased 8.32%.Plastic film and liquid film could increase temperature and soil moisture in returning green stage,0～20 cm soil water content increased 4.4% and 3.0% respectively.Straw mulching increase soil moisture in key growth stage,0～100 cm soil water storage increased 15.2 mm and 9.8 mm in returning green stage and heading stage,as the inhabited for winter wheat by low temperature efficiency in early stage,but shows better in late stage.Different mulching could increase the water use efficiency.The best choice is straw mulching,which is good for soil fertilizer and soil sustainable use.",
        "keywords": [
            "dryland wheat",
            "water use efficiency",
            "mulching",
            "growth",
            "water dynamics"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Luoyang Academy of Agricultural Sciences,Luoyang,He'nan ,China"
            },
            {
                "name": "WANG Yu-hong",
                "org": "Luoyang Academy of Agricultural Sciences,Luoyang,He'nan ,China"
            },
            {
                "name": "LI Jun-hong",
                "org": "Luoyang Academy of Agricultural Sciences,Luoyang,He'nan ,China"
            },
            {
                "name": "DING Zhi-qiang",
                "org": "Luoyang Academy of Agricultural Sciences,Luoyang,He'nan ,China"
            },
            {
                "name": "YAO Yu-qing",
                "org": "Luoyang Academy of Agricultural Sciences,Luoyang,He'nan ,China"
            }
        ],
        "venue": "Agricultural Research in the Arid Areas",
        "year": 2008
    },
    "W2U4NSvs": {
        "id": "W2U4NSvs",
        "title": "Effect of regulated deficit irrigation on photosynthetic characteristics & water use efficiency of winter wheat",
        "abstract": "Studies on photosynthetic characteristics & water use efficiency of winter wheat under the condition of controlling rainfall & different regulated deficit irrigations.The results showed that the yield of winter wheat would be better along with the increasing of irrigations.At the same irrigation,the yield of jointing water was higher than that of booting water.The WUE of jointing water was the highest among all the treatments.With the increase and postponement of water,the decrease of the LAI after blooming got lower.During filling stage,the LAI of different treatments was in such order: the LAI of treatment E was number one,the LAI of treatment D was ranked the second,that of treatment C the third,that of treatment B was the fourth,and the last one was no irrigation treatment A(CK),and the Fv/F0 value & Fv/Fm value of fluorescence parameters of wheat flags were also improved,and Chl content was improved,too.But the MDA content was decreased.",
        "keywords": [
            "water use efficiency",
            "regulated deficit irrigation",
            "leaf area index",
            "photosynthetic characteristics"
        ],
        "authors": [
            {
                "name": "WANG Yu-hong",
                "org": "Luoyang Academy of Agricultural Sciences,Luoyang,He'nan ,China"
            },
            {
                "name": "YAO Yu-qing",
                "org": "Luoyang Academy of Agricultural Sciences,Luoyang,He'nan ,China"
            },
            {
                "name": "LI Jun-hong",
                "org": "Luoyang Academy of Agricultural Sciences,Luoyang,He'nan ,China"
            },
            {
                "name": "DING Zhi-qiang",
                "org": "Luoyang Academy of Agricultural Sciences,Luoyang,He'nan ,China"
            },
            {
                "name": "LI Shuang-hui",
                "org": "Luoyang Academy of Agricultural Sciences,Luoyang,He'nan ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Luoyang Academy of Agricultural Sciences,Luoyang,He'nan ,China"
            }
        ],
        "venue": "Agricultural Research in the Arid Areas",
        "year": 2008
    },
    "lpeDSJp6": {
        "id": "lpeDSJp6",
        "title": "Effects of Conservation Tillage on Rainfall Runoff,Soil Water Infiltration and Distribution on Loess Sloping Farming in the Western Part of Henan",
        "abstract": "On based site-specific long-term trials from 1999 year to 2007 year,this paper studied effects of subsoiling(ST) with mulching and no-till with mulching(NT) on rainfall,soil water infiltration and distribution on loess dryland sloping(gradient is 8°) farming in the western part of Henan.The results as following:(1) Compared with conventional tillage(CK),ST and NT postponed runoff time,shortened runoff sustained time after the rainfall end.Runoff coefficient with ST and NT treatments decreased 97.49% and 81.20% than that of CK,respectively.In addition,runoff and soil loss quantity with the two conservation tillages decreased more 80% than that of CK.NT was best on soil and water holding in them,but it could also boost significantly more yield in short of water in growth period,in fallow summer and in a whole year,increasing average 3.70% than that of CK.Under ST and NT treatments,which had very little soil and water loss under rainfall rate 123 mm/h and 40 minutes rainfall.(2) Soil water infiltration rate with CK was highest in them at the beginning of rainfall,and then sharply dropped,at 4 minute,was lowest.During stabilization of rainfall infiltration from 3 minute to 60 minute,average infiltration rates with NT and ST were same,0.07 mm/s,1.40 times than that of CK.The change of soil water infiltration rate was least,its steady rate biggest in them.(3) Soil water under NT and ST treatments was higher than that of CK before rainfall.The soil depth where soil water infiltrated after 1 hour the end of rainfall(74.2 mm) was higher than that of CK,by 30～40 cm.Water increases in 160 cm soil under the two conservation tillages was more 2 times than that of CK.",
        "keywords": [
            "sloping dryland",
            "conservational tillage",
            "soil water distribution",
            "soil and water conservation"
        ],
        "authors": [
            {
                "name": "WANG Yu-hong",
                "org": "Luoyang Academy of Agricultural Sciences,Luoyang "
            },
            {
                "name": "CAI Dian-xiong",
                "org": "Institute of Agricultural Resources and Regional Planning,Chinese Academy of Agricultural Sciences,Beijing "
            },
            {
                "name": "YAO Yu-qing",
                "org": "Luoyang Academy of Agricultural Sciences,Luoyang "
            },
            {
                "name": "LV Jun-jie",
                "org": "Luoyang Academy of Agricultural Sciences,Luoyang "
            },
            {
                "name": "LI Jun-hong",
                "org": "Luoyang Academy of Agricultural Sciences,Luoyang "
            },
            {
                "name": "ZHANG Jie",
                "org": "Luoyang Academy of Agricultural Sciences,Luoyang "
            }
        ],
        "venue": "Journal of Soil and Water Conservation",
        "year": 2008
    },
    "gGwKVclo": {
        "id": "gGwKVclo",
        "title": "Soil carbon change and yield increase mechanism of conservation tillage on sloping drylands in semi-humid arid area",
        "abstract": "A long-term field experiment was conducted in the semi-humid areas of western Henan Province to study the changes of soil organic carbon (SOC), soil microbial biomass carbon (SMBC) and yield increase mechanism of wheat. The results show that SOC increases significantly under sub-soiling tillage and no-tillage, especially in cultivated soil layers. SOC (6.79 g·kg-1) is highest under sub-soiling, which is 13.8% higher than that under conventional tillage. SOC under no-tillage is 11.6% higher than conventional tillage, which also drops by 1.4% under reduced tillage. The deeper the soil layer, the lower SOC content is. SMBC content occurs in the following order: no-tillage>sub-soiling>conventional tillage>reduced tillage; while SMBC contents under no-tillage, sub-soiling tillage and reduced tillage are 79.3%, 19.9% and-2.5% higher than that of conventional tillage. Ratio of SMBC to SOC under no-tillage and sub-soiling are 3.11% and 2.04%. Through out the field trial experiments, sub-soiling yields the highest. No-tillage increases wheat yield, except in very rainy years. No-tillage and sub-soiling tillage store more water in the soil and improve accumulation of dry matter during the later growing stage of winter wheat, postpone plant co-senescence in wheat.",
        "keywords": [
            "Semi-humid arid area",
            "Conservation tillage",
            "SMBC/SOC",
            "Soil microbial biomass carbon (SMBC)",
            "Yield increase mechanism",
            "Sloping field",
            "Soil organic carbon (SOC)"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Luoyang Academy of Agricultural Sciences, Luoyang , China"
            },
            {
                "name": "YAO Yu-Qing",
                "org": "Luoyang Academy of Agricultural Sciences, Luoyang , China"
            },
            {
                "name": "JIN Ke",
                "org": "Institute of Agricultural Resources andRegional Planning, Chinese Academy of Agricultural Sciences, Beijing , China"
            },
            {
                "name": "WANG Cong-Hui",
                "org": "Luoyang Academy of Agricultural Sciences, Luoyang , China"
            },
            {
                "name": "WANG Yu-Hong",
                "org": "Luoyang Academy of Agricultural Sciences, Luoyang , China"
            },
            {
                "name": "LI Jun-Hong",
                "org": "Luoyang Academy of Agricultural Sciences, Luoyang , China"
            },
            {
                "name": "DING Zhi-Qiang",
                "org": "Luoyang Academy of Agricultural Sciences, Luoyang , China"
            }
        ],
        "venue": "Chinese Journal of Eco-Agriculture",
        "year": 2008
    },
    "p3my3OS6": {
        "id": "p3my3OS6",
        "title": "Study on long-term site-specific conservation tillage on sloping dryland in the western part of Henan——Ⅰ. Effects of No-till and subsoiling with mulching on growth characteristics and yield of winter wheat",
        "abstract": "Based on long-term site-specific trials from 1999 to 2006,this paper studied the effects of subsoiling(ST) with mulching and no-till with mulching(NT) on yield and growth characteristics of winter wheat.The results were as following: compared with conventional tillage(CK),ST and NT could increase the yield of winter wheat with their application going on,and ST was better than NT.Compared with CK,ST increased yield by 4.88%～20.90%,averaging 8.77% for 7 years.NT decreased yield in early application,but it could boost significantly yield in dry years,with an average increasing rate of 3.70% over CK.Under ST and NT treatments,winter wheat grew more slowly,which behaved as falling of plant height,decreasing of leaves of the main stem,tillers per plant,second roots,weight and leaf area index in early growth period.After jointing,winter wheat developed faster under the two kinds of conservational tillage.Except tillers per plant,the others were beyond that of CK.The maximum filling rate was enhanced under the conservational tillage,delaying last filling slowing and prolonging tilling time,so that 1000-grain weight was improved.",
        "keywords": [
            "yield",
            "sloping dryland",
            "conservational tillage",
            "long-term site-specific trial"
        ],
        "authors": [
            {
                "name": "WANG Yu-hong",
                "org": "Luoyang Academy of Agricultural Sciences,Luoyang,He'nan ,China"
            },
            {
                "name": "CAI Dian-xiong",
                "org": "Institute of Agricultural Resources and Regional Planning,Chinese Academy of Agricultural Sciences,Beijing 10082,China"
            },
            {
                "name": "YAO Yu-qing",
                "org": "Luoyang Academy of Agricultural Sciences,Luoyang,He'nan ,China"
            },
            {
                "name": "WANG Xiao-bin",
                "org": "Institute of Agricultural Resources and Regional Planning,Chinese Academy of Agricultural Sciences,Beijing 10082,China"
            },
            {
                "name": "LI Jun-hong",
                "org": "Luoyang Academy of Agricultural Sciences,Luoyang,He'nan ,China"
            },
            {
                "name": "DING Zhi-qiang",
                "org": "Luoyang Academy of Agricultural Sciences,Luoyang,He'nan ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Luoyang Academy of Agricultural Sciences,Luoyang,He'nan ,China"
            }
        ],
        "venue": "Agricultural Research in the Arid Areas",
        "year": 2009
    },
    "vEVdNwBp": {
        "id": "vEVdNwBp",
        "title": "Benefit Analysis on Conservation Tillage in Farmland under Perennial Orientation Research",
        "abstract": "Eight years continuous orientation researches on typical upland dry land in Luoyang indicated that SB-cover and NT-cover techniques could significantly increase soil capability to rainfall,and the highest increasing extent was over 20 percentage compared to CK.The yield increasing effect of SB-cover treatment was better than that of NT-cover treatment.Compared to CK,both SB-cover and NT-cover could heighten rainfall use efficiency only after 3 years from beginning of this expriment.",
        "keywords": [
            "Conservation tillage",
            "Farmland",
            "Benefit analysis",
            "Orientation research"
        ],
        "authors": [
            {
                "name": "LV Jun-jie",
                "org": ""
            },
            {
                "name": "DING Zhi-qiang",
                "org": ""
            },
            {
                "name": "LI Jun-hong",
                "org": ""
            },
            {
                "name": "WU Jian-feng",
                "org": ""
            },
            {
                "name": "WANG Yu-hong",
                "org": ""
            },
            {
                "name": "ZHANG Jie",
                "org": ""
            },
            {
                "name": "ZHANG Shao-lan",
                "org": ""
            }
        ],
        "venue": "Crop Research",
        "year": 2009
    },
    "2phCL2RQ": {
        "id": "2phCL2RQ",
        "title": "Study on long-term site-specific conservation tillage on sloping dryland in the Western part of Henan——Ⅱ.Effects of no-till and subsoiling with mulching on soil temperature in wheat field",
        "abstract": "On based long-term site-specific trials,this paper studied the effects of conservation tillage(subsoiling tillage with mulching,ST and no-till with mulching,NT) and conventional tillage(CT) on soil temperature on dryland sloping farming in the western part of Henan.Temperature data loggers were used to record the temperature at the depth of 0,5,15 cm and 30 cm under the treatments every 2 hours from Oct.2004 to Sept.2005.The results showed:(1) ST and NT could weaken the change of average soil temperature of 0～30 cm layer every rmonth in a year.The soil temperature under the two conservation tillages was higher from Dec.2004 to Jan.2005,obviously lower from Jun to Sept.2005,compared with CT.(2) ST and NT had the effect that temperature of surface soil was increased in higher temperature,decreased in lower temperature during 24 hour of a day.The effect was weakened with soil layer adding up.At 15 cm layer,soil temperature under ST and NT was lower from winter wheat planting to joiting stage.Furthermore,ST made the temperature higher than that of CK.(3) Winter wheat growth was restrained under the treatments of ST and NT before wheat joiting,which made height fall,tillers,leaves and second roots decrease,dry matter accumulation rate slow down.After that,the items except tillers under the two conservation tillages gradually overtake that of CK.",
        "keywords": [
            "soil temperature",
            "conservation tillage",
            "long-term site-specific trials",
            "conventional tillage"
        ],
        "authors": [
            {
                "name": "WANG Yu-hong",
                "org": "Luoyang Academy of Agricultural Sciences,Luoyang,He'nan ,China"
            },
            {
                "name": "CAI Dian-xiong",
                "org": "Institute of Agricultural Resources and Regional Planning,Chinese Academy of Agricultural Sciences,Beijing 10082,China"
            },
            {
                "name": "YAO Yu-qing",
                "org": "Luoyang Academy of Agricultural Sciences,Luoyang,He'nan ,China"
            },
            {
                "name": "WU Xue-ping",
                "org": "Institute of Agricultural Resources and Regional Planning,Chinese Academy of Agricultural Sciences,Beijing 10082,China"
            },
            {
                "name": "Lü Jun-jie",
                "org": "Luoyang Academy of Agricultural Sciences,Luoyang,He'nan ,China"
            },
            {
                "name": "LI Jun-hong",
                "org": "Luoyang Academy of Agricultural Sciences,Luoyang,He'nan ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Luoyang Academy of Agricultural Sciences,Luoyang,He'nan ,China"
            }
        ],
        "venue": "Agricultural Research in the Arid Areas",
        "year": 2010
    },
    "dgiyP9UB": {
        "id": "dgiyP9UB",
        "title": "Study on site-specific long-term conservation tillage on dry sloping farmland in Western He'nan——Ⅲ.Analysis of conservation tillage on comprehensive benefits",
        "abstract": "This paper analyzed economical benefit,social benefit and environmental benefit of conservation tillage in western part of Henan so that proper tillage treatments can be selected to implement sustaining agricultural development.The research took use of field plots trial,field simulation rainfall trial and demonstration in farm field at the Songzhuang experiment station of Luoyang Dryland Farming Experiment Base of the Chinese Academy of Agricultural Sciences from 1999～2006.Compared with conventional tillage(CK),subsoil tillage with straw stubble mulch(ST) and no-tillage with straw stubble mulch(NT) could decrease production cost by 412 yuan and 562 yuan per hm2,increase wheat yield(average of 7 years) by 8.78% and 3.70%,net income by 888.2 yuan and 762.7 yuan,heighten WUE by 1.0 kg/(mm·hm2) and 0.4 kg/(mm·hm2),and boost rainfall storeage ratio by 15.8% and 12.5%.Under natural rainfall and simulated rainfall experiments,conservation tillage had better effect on soil and water conservation with its implementation time continuing.The effect of ST was better than that of NT.But 2 years later,the effect of NT was little better than that of ST.Soil nutrient kalium loss of the sloping loess farmland was the most,secondly soil nitrogen,while soil phosphorus was the smallest.ST and NT could decrease runoff of nutrient concentration and quantity.",
        "keywords": [
            "dry sloping farmland in Western Henan",
            "conservation tillage",
            "comprehensive benefits"
        ],
        "authors": [
            {
                "name": "WANG Yu-hong",
                "org": "Luoyang Academy of Agricultural Sciences,Luoyang,Henan ,China"
            },
            {
                "name": "YAO Yu-qing",
                "org": "Luoyang Academy of Agricultural Sciences,Luoyang,Henan ,China"
            },
            {
                "name": "CAI Dian-xiong",
                "org": "Institute of Agricultural Resources and Regional Planning,Chinese Academy of Agricultural Sciences,Beijing 10082,China"
            },
            {
                "name": "WANG Xiao-bin",
                "org": "Institute of Agricultural Resources and Regional Planning,Chinese Academy of Agricultural Sciences,Beijing 10082,China"
            },
            {
                "name": "LV Jun-jie",
                "org": "Luoyang Academy of Agricultural Sciences,Luoyang,Henan ,China"
            },
            {
                "name": "LI Jun-hong",
                "org": "Luoyang Academy of Agricultural Sciences,Luoyang,Henan ,China"
            },
            {
                "name": "DING Zhi-qiang",
                "org": "Luoyang Academy of Agricultural Sciences,Luoyang,Henan ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Luoyang Academy of Agricultural Sciences,Luoyang,Henan ,China"
            }
        ],
        "venue": "Agricultural Research in the Arid Areas",
        "year": 2010
    },
    "wYx00Y02": {
        "id": "wYx00Y02",
        "title": "Effects of long-term conservation tillage on soil enzyme activity of sloping dryland and its relation to soil fertility",
        "abstract": "In order to explore soil enzyme activity and its relation to soil fertility under the circumstances of long-term conservation tillage,determination and analysis were conducted of the soil enzyme activity and soil fertility after 7 year conservation tillage in sloping dryland of west Henan Province.The results showed that the activity of soil urease,catalase and invertase increased obviously under sub-soiling tillage and no-tillage,especially the enzyme activity in 0～10 cm soil layer,and the soil urease activity increased most.The correlation analysis of soil enzyme activity showed that there was a positive correlation between urease and the content of organic matter,total P,available P,available K and available N,between invertase and the content of total P and total K,and between catalase and the content of total P.It indicated that soil urease activity can be used as an index of soil fertility,while catalase may play an auxiliary function.",
        "keywords": [
            "nutrients",
            "soil fertility",
            "conservation tillage",
            "enzyme activity",
            "sloping field",
            "correlation analysis",
            "soil"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Luoyang Academy of Agricultural Sciences,Luoyang,He'nan ,China;Luoyang Dryland Farming Experiment Station,CAAS,Luoyang,He'nan ,China"
            },
            {
                "name": "YAO Yu-qing",
                "org": "Luoyang Academy of Agricultural Sciences,Luoyang,He'nan ,China;Luoyang Dryland Farming Experiment Station,CAAS,Luoyang,He'nan ,China"
            },
            {
                "name": "CAI Dian-xiong",
                "org": "Luoyang Dryland Farming Experiment Station,CAAS,Luoyang,He'nan ,China;Institute of Agricultural Resources and Regional Planning,CAAS,Beijing ,China"
            },
            {
                "name": "JIN Ke",
                "org": "Institute of Agricultural Resources and Regional Planning,CAAS,Beijing ,China"
            },
            {
                "name": "LI Jun-hong",
                "org": "Luoyang Academy of Agricultural Sciences,Luoyang,He'nan ,China;Luoyang Dryland Farming Experiment Station,CAAS,Luoyang,He'nan ,China"
            },
            {
                "name": "DING Zhi-qiang",
                "org": "Luoyang Academy of Agricultural Sciences,Luoyang,He'nan ,China;Luoyang Dryland Farming Experiment Station,CAAS,Luoyang,He'nan ,China"
            },
            {
                "name": "SUN Jing-ke",
                "org": "Pingdingshan Collage of Technology,Pingdingshan,He'nan ,China"
            },
            {
                "name": "TAN Zun-she",
                "org": "Luoyang Bureau of Agricultural,Luoyang,He'nan ,China"
            },
            {
                "name": "WU Jian-feng",
                "org": "Luoyang Academy of Agricultural Sciences,Luoyang,He'nan ,China;Luoyang Dryland Farming Experiment Station,CAAS,Luoyang,He'nan ,China"
            },
            {
                "name": "ZHANG Shao-lan",
                "org": "Luoyang Academy of Agricultural Sciences,Luoyang,He'nan ,China"
            }
        ],
        "venue": "Agricultural Research in the Arid Areas",
        "year": 2011
    },
    "nME7fhjc": {
        "id": "nME7fhjc",
        "title": "Effects of irrigation and fertilization coupling on protein and amino acids contents in grains of winter wheat",
        "abstract": "To evaluate effects of different water,nitrogen and phosphorus fertilizers and their interactions on grain quality of winter wheat in semiarid region,the experiment was carried out in rain-sheltered condition in Luoyang,west part of Henan Province during crop season of 2009～2010.Grain protein content and contents of amino acid components were tested.The results indicated that irri-gation,application of nitrogen had significant effects on grain protein and amino acids contents(P≤0.01) of winter wheat.The in-teraction of irrigation and nitrogen fertilization also presented significant effects(P≤0.05 or ≤0.01).No significant effect of P fer-tilization on protein and amino acids contents was observed.Protein and amino acids contents in wheat grains increased with in-creasing nitrogen fertilization rate,but dropped with increasing of irrigation amount.However,as irrigation amount was above 282.0 mm,and nitrogen fertilization rate was above 179.2 kg·hm 2,the changes became less obvious.Protein content decreased as the ni-trogen fertilization rate above 179.2 kg·hm 2.The trend of ETT/ATT(percent of essential amino acids to total amino acids) was con-trary to that of amino acids contents.The contents of protein and amino acids in wheat grains reached the highest in treatment of N105P42W127 with nitrogen fertilization rate of 105 kg(N)·hm 2,phosphorus fertilization rate of 42 kg(P2O5)·hm 2 and irrigation amount during growing season of 127 mm.While ETT/ATT reached the highest in treatment of N30.8P126W282 with nitrogen fertiliza-tion rate of 30.8 kg(N)·hm 2,phosphorus fertilization rate of 126 kg(P2O5)·hm 2 and irrigation amount during growing season of 282 mm.The grain yield increased with the increasing of irrigation,and water use efficiency was higher with high yield.Overall,N179.2P126W282 with nitrogen fertilization rate of 179.2 kg(N)·hm 2,phosphorus fertilization rate of 126 kg(P2O5)·hm 2 and irrigation amount during growing season of 282 mm was the best treatment.",
        "keywords": [
            "Protein content",
            "Phosphorus fertilizer",
            "Nitrogen fertilizer",
            "Irrigation",
            "Amino acid content",
            "Wheat grain"
        ],
        "authors": [
            {
                "name": "ZHENG Zhi-Song",
                "org": "College of Agronomy,Gansu Agricultural University,Lanzhou ,China;Henan Agricultural Broadcasting and Television College,Zhengzhou ,China"
            },
            {
                "name": "WANG Chen-Yang",
                "org": "Henan Agricultural University,Zhengzhou ,China"
            },
            {
                "name": "NIU Jun-Yi",
                "org": "College of Agronomy,Gansu Agricultural University,Lanzhou ,China"
            },
            {
                "name": "ZHANG Mei-Wei",
                "org": "Henan Agricultural University,Zhengzhou ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Luoyang Agriculture Science College,Luoyang ,China"
            },
            {
                "name": "YAO Yu-Qing",
                "org": "Luoyang Agriculture Science College,Luoyang ,China"
            }
        ],
        "venue": "Chinese Journal of Eco-Agriculture",
        "year": 2011
    },
    "LxwNz51O": {
        "id": "LxwNz51O",
        "title": "Effects of water,nitrogen and phosphorus coupling on starch paste properties of winter wheat",
        "abstract": "A field experiment was conducted under rain-shelter conditions in Luoyang(Henan Province) during the 2009-2010 and 2010-2011 cropping seasons by using \"Luohan 2\" winter wheat cultivar.The objective of the experiment was to evaluate the effects of irrigation and nitrogen/phosphorus fertilization on grain quality of winter wheat in the semiarid region of West Henan Province.The experiment was a factorial combination of 5 irrigation,nitrogen and phosphorus application rates,each in 3 replicas.The effects of water,nitrogen and phosphorus application rates and interactions on starch paste parameters of winter wheat were determined.The results showed that the application of nitrogen and phosphorus fertilizers had significant effects on starch paste properties of winter wheat(P≤0.05 or P≤0.01).Main starch viscosity parameters(peak viscosity,initial viscosity and final viscosity) increased sig-nificantly as nitrogen application increased from 0 kg·hm 2 to 105 kg·hm 2,and after peaking at 105 kg·hm 2 decreased with nitrogen application rate.Starch viscosity parameters reached the highest values at phosphorus application rate of 168 kg·hm 2.Irrigation had no significant effect on starch paste properties.However,irrigation and nitrogen interactions significantly influenced some starch paste properties.Overall,combined treatments of nitrogen,phosphorus and water at N105P168W217.5-i.e.,105 kg(N)·hm 2,168 kg(P2O5)·hm 2 and 217.5 mm irrigation-produced the best starch quality.Statistical analysis indicated a significant positive correlation between starch paste properties and grain yield in the 2009-2010 cropping season and not in the 2010-2011 crop season.This suggested that there existed the possibility for improvement of both grain yield and starch paste quality in the region.",
        "keywords": [
            "Phosphorus fertilizer",
            "Nitrogen fertilizer",
            "Irrigation",
            "West Henan Semi-arid region",
            "Irrigation and fertilization interaction",
            "Starch paste property",
            "Wheat grain"
        ],
        "authors": [
            {
                "name": "ZHENG Zhi-Song",
                "org": "College of Agronomy,Gansu Agricultural University,Lanzhou ,China;Henan Agricultural Broadcasting and Television College,Zhengzhou ,China"
            },
            {
                "name": "WANG Chen-Yang",
                "org": "Henan Agricultural University,Zhengzhou ,China"
            },
            {
                "name": "ZHANG Mei-Wei",
                "org": "Henan Agricultural University,Zhengzhou ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Luoyang Academy of Agriculture and Forestry Sciences,Luoyang ,China"
            },
            {
                "name": "YAO Yu-Qing",
                "org": "Luoyang Academy of Agriculture and Forestry Sciences,Luoyang ,China"
            },
            {
                "name": "NIU Jun-Yi",
                "org": "College of Agronomy,Gansu Agricultural University,Lanzhou ,China"
            }
        ],
        "venue": "Chinese Journal of Eco-Agriculture",
        "year": 2012
    },
    "yvuSjqyL": {
        "id": "yvuSjqyL",
        "title": "Synthesis, structure and reactivity of tert-butyldimethylsilylcyclopentadeinyl lanthanide chlorides, including crystal structures of [(C5H4SiMe2But)2Gd (μ-Cl)]2 and",
        "abstract": "Reactions of anhydrous lanthanide trichloride with one or two equivalent of tert-butyldimethylsilylcyclopentadienyl (Cpt) potassium salt in THF afford mono(tert-butyldimethylsilylcyclopentadienyl) lanthanide dichloride complexes Cpt LnCl2(THF) 3 [Ln = Y(1), Er(2)] and bis(tert-butyldimethylsilylcyclopentadienyl)lanthanide chlorides [Cp2 tLn(μ-Cl)]2 [Ln = Gd(3), Er(4), Yb(5)], respectively. DyCl3 reacts with KCpt in THF, followed by the treatment with two equivalents of C5 H5Na to form the mixed-ring complex Cpt Cp2Dy(THF) (6). Reaction of 4 with LiNPr2 i and subsequently with one equivalent of PhNCO in THF give the PhNCO insertion product Cp2 tEr [OC(NPr2 i)NPh](THF) (7). Complex 4 reacts with one equivalent of sodium benzothiazole-2-thiolate (NaSBT) to yield Cp2 tEr(SBT)(THF) (8). Complexes 1-8 have been characterized by elemental analyses, infrared, 1H-NMR and mass spectroscopies. The molecular structures of 3 and 8 were determined by single crystal X-ray diffraction. © 2002 Published by Elsevier Science B.V.",
        "keywords": [
            "Crystal structures",
            "Insertion",
            "Organolanthanide",
            "Substituted cyclopentadienyl"
        ],
        "authors": [
            {
                "name": "Xigeng Zhou",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Lixin Zhang",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "ChunMei Zhang",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Ming Zhu",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Ruifang Cai",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "ZuEn Huang",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Zixiang Huang",
                "org": "State Key Laboratory of Structural Chemistry, Fuzhou(Chinese Academy of Sciences),Fuzhou,China"
            },
            {
                "name": "QiangJin Wu",
                "org": "State Key Laboratory of Structural Chemistry, Fuzhou(Chinese Academy of Sciences),Fuzhou,China"
            }
        ],
        "venue": "Journal of Organometallic Chemistry",
        "year": 2002
    },
    "NiSzPDl7": {
        "id": "NiSzPDl7",
        "title": "Synthesis, structure and reactivity of tert-butyldimethylsilylcyclopentadienyl lanthanide chlorides, including crystal structures of [(C 5H 4SiMe 2Bu t ) 2Gd(μ-Cl)] 2 and (C 5H 4SiMe 2Bu t ) 2Er(SBT)(THF)",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Xi-Geng Zhou",
                "org": "Laboratory of Molecular Catalysis and Innovative Material, Department of Chemistry, Fudan University, Shanghai 200433, People's Republic of China"
            },
            {
                "name": "Li-Xin Zhang",
                "org": "Laboratory of Molecular Catalysis and Innovative Material, Department of Chemistry, Fudan University, Shanghai 200433, People's Republic of China"
            },
            {
                "name": "Chun-Mei Zhang",
                "org": "Laboratory of Molecular Catalysis and Innovative Material, Department of Chemistry, Fudan University, Shanghai 200433, People's Republic of China"
            },
            {
                "name": "Jie Zhang",
                "org": "Laboratory of Molecular Catalysis and Innovative Material, Department of Chemistry, Fudan University, Shanghai 200433, People's Republic of China"
            },
            {
                "name": "Ming Zhu",
                "org": "Laboratory of Molecular Catalysis and Innovative Material, Department of Chemistry, Fudan University, Shanghai 200433, People's Republic of China"
            },
            {
                "name": "Rui-Fang Cai",
                "org": "Laboratory of Molecular Catalysis and Innovative Material, Department of Chemistry, Fudan University, Shanghai 200433, People's Republic of China"
            },
            {
                "name": "Zu-En Huang",
                "org": "Laboratory of Molecular Catalysis and Innovative Material, Department of Chemistry, Fudan University, Shanghai 200433, People's Republic of China"
            },
            {
                "name": "Zi-Xiang Huang",
                "org": "State Key Laboratory of Structural Chemistry, Fuzhou 350002, People's Republic of China"
            },
            {
                "name": "Qiang-Jin Wu",
                "org": "State Key Laboratory of Structural Chemistry, Fuzhou 350002, People's Republic of China"
            }
        ],
        "venue": "Journal of Organometallic Chemistry",
        "year": 2002
    },
    "j3xzmR9R": {
        "id": "j3xzmR9R",
        "title": "Insertion of carbodiimide into the Ln-C σ-bond of organolanthanide complexes. Synthesis, reaction, and characterization of organolanthanide amidinates (C5H5)2Ln[tBuN-..C(n Bu)-..NtBu] (Ln = Er, Gd, Y)",
        "abstract": "The synthesis, structures, and reactivity of new lanthanocene complexes incorporating amidinate ligand [tBuN-..C(nBu)-..NtBu] are described. Treatment of Cp2LnnBu (Ln = Er (1), Y (2), Gd (3)) with N,N′-di-tert-butylcarbodiimide results in monoinsertion of carbodiimide into the Ln-C σ-bond to yield the title compounds Cp2Ln[tBuN-..C(nBu)-..N tBu] (Ln = Er (4), Y (5), Gd (6)). Complexes 4-6 were characterized by elemental analysis and IR and mass spectroscopies. The structures of complexes 4 and 5 were determined through X-ray single-crystal diffraction analysis. It is shown that compound 5 is a fine catalyst for cyclotrimerization of phenyl isocyanate.",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Ruyi Ruan",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "ZeHuai Shao",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Ruifang Cai",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "and linhong weng",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Xigeng Zhou",
                "org": "Fudan University(Fudan University),Shanghai,China"
            }
        ],
        "venue": "Organometallics",
        "year": 2002
    },
    "Fd2E68vB": {
        "id": "Fd2E68vB",
        "title": "Novel Cp2LnX-mediated coupling-cyclization of propargyl bromide: a new construction of the benzene ring skeleton.",
        "abstract": "In the presence of Cp2LnX-HgCl2, the treatment of RC identical to CCH2Br with Mg leads to the formation of benzene derivatives C6H4R2-1,2 (R = H, Ph) in moderate yield, which provides a new method for the construction of the benzene ring skeleton.",
        "keywords": [],
        "authors": [
            {
                "name": "Ruyi Ruan",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Xigeng Zhou",
                "org": ""
            },
            {
                "name": "Ruifang Cai",
                "org": ""
            }
        ],
        "venue": "Chemical communications (Cambridge, England)",
        "year": 2002
    },
    "h8Tsj4ZW": {
        "id": "h8Tsj4ZW",
        "title": "Synthesis, structure and reactivity of tert -butyldimethylsilylcyclopentadienyl lanthanide chlorides, including crystal structures of [(C 5 H 4 SiMe 2 Bu t ) 2 Gd(μ-Cl)] 2 and (C 5 H 4 SiMe 2 Bu t ) 2 Er(SBT)(THF)",
        "abstract": "",
        "keywords": [
            "crystal structures",
            "mass spectroscopy",
            "infrared",
            "potassium",
            "x ray diffraction",
            "insertion",
            "crystal structure",
            "molecular structure",
            "single crystal"
        ],
        "authors": [
            {
                "name": "xigeng zhou",
                "org": "fudan university"
            },
            {
                "name": "lixin zhang",
                "org": "fudan university"
            },
            {
                "name": "chunmei zhang",
                "org": "fudan university"
            },
            {
                "name": "jie zhang",
                "org": "fudan university"
            },
            {
                "name": "ming zhu",
                "org": "fudan university"
            },
            {
                "name": "ruifang cai",
                "org": "fudan university"
            },
            {
                "name": "zuen huang",
                "org": "fudan university"
            },
            {
                "name": "qiangjin wu",
                "org": ""
            }
        ],
        "venue": "Journal of Organometallic Chemistry",
        "year": 2002
    },
    "A2mdt9Ck": {
        "id": "A2mdt9Ck",
        "title": "Synthesis, structure and reactivity of tert-butyldimethylsilylcyclopentadienyl lanthanide chlorides, including crystal structures of [(C5H4SiMe2But)2Gd(μ-Cl)]2 and (C5H4SiMe2But)2Er(SBT)(THF)",
        "abstract": "A series of tert -butyldimethylsilylcyclopentadienyl lanthanide chlorides Cp t LnCl 2 (THF) (Ln=Y, Er) and [Cp t 2 LnCl] 2 (Ln=Gd, Er, Yb) were prepared by the reactions of LnCl 3 with one or two equivalents of Cp t K in THF. Cp t DyCl 2 (THF) 3 reacted with two equivalents of CpNa to form the mixed-ring complex Cp 2 Cp t Dy(THF). Reaction of [Cp t 2 ErCl] 2 with LiNPr i 2 and subsequently with PhNCO in THF gave the PhNCO insertion product Cp t 2 Er[OC(NPr i 2 )NPh](THF). [Cp t 2 ErCl] 2 reacted with benzothiazole-2-thiolate sodium (NaSBT) to yield Cp t 2 Er(SBT)(THF), which was structurally characterized by the X-ray diffraction analysis.",
        "keywords": [
            "Substituted cyclopentadienyl",
            "Insertion",
            "Crystal structures",
            "Organolanthanide"
        ],
        "authors": [
            {
                "name": "Xi-Geng Zhou",
                "org": ""
            },
            {
                "name": "Li-Xin Zhang",
                "org": "Laboratory of Molecular Catalysis and Innovative Material, Department of Chemistry, Fudan University, Shanghai 200433, People's Republic of China"
            },
            {
                "name": "Chun-Mei Zhang",
                "org": "Laboratory of Molecular Catalysis and Innovative Material, Department of Chemistry, Fudan University, Shanghai 200433, People's Republic of China"
            },
            {
                "name": "Jie Zhang",
                "org": "Laboratory of Molecular Catalysis and Innovative Material, Department of Chemistry, Fudan University, Shanghai 200433, People's Republic of China"
            },
            {
                "name": "Ming Zhu",
                "org": "Laboratory of Molecular Catalysis and Innovative Material, Department of Chemistry, Fudan University, Shanghai 200433, People's Republic of China"
            },
            {
                "name": "Rui-Fang Cai",
                "org": "Laboratory of Molecular Catalysis and Innovative Material, Department of Chemistry, Fudan University, Shanghai 200433, People's Republic of China"
            },
            {
                "name": "Zu-En Huang",
                "org": "Laboratory of Molecular Catalysis and Innovative Material, Department of Chemistry, Fudan University, Shanghai 200433, People's Republic of China"
            },
            {
                "name": "Zi-Xiang Huang",
                "org": "State Key Laboratory of Structural Chemistry, Fuzhou 350002, People's Republic of China"
            },
            {
                "name": "Qiang-Jin Wu",
                "org": "State Key Laboratory of Structural Chemistry, Fuzhou 350002, People's Republic of China"
            }
        ],
        "venue": "Journal of Organometallic Chemistry",
        "year": 2002
    },
    "ryG47kYO": {
        "id": "ryG47kYO",
        "title": "Insertion of carbodiimide into the Ln-N σ-bond of organolanthanide complexes. Synthesis and characterization of organolanthanide guanidinates (C5H5)2Ln[iPrN-C (NiPr2)-NiPr] (Ln = Yb, Dy, Gd)",
        "abstract": "The synthesis and structures of three new lanthanide complexes incorporating tetra-substituted guanidinate ligand [i PrN-C(NiPr2)-NiPr] are described. Treatment of Cp2LnNiPr2(THF) (Ln=Yb, Dy, Gd) with N,N′-di-isopropyl-carbodiimide results in mono-insertion of carbodiimide into the Ln-N σ-bond to yield Cp2Ln[iPrN-C(NiPr2)-N iPr] (Ln=Yb(1), Dy(2), Gd(3)), providing an efficient method for the synthesis of organolanthanide guanidinate complexes. It was found that an excess of N,N′-di-isopropyl-carbodiimide did not affect the nature of the final product. Complexes 1-3 were characterized by elemental analysis, IR and mass spectroscopies. Complexes 1 and 2 were determined by the X-ray single crystal diffraction analysis. © 2003 Elsevier Science B.V. All rights reserved.",
        "keywords": [
            "Carbodiimide",
            "Cyclopentadienyl",
            "Insertion",
            "Organolanthanide",
            "Structures"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Ruifang Cai",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Linhong Weng",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Xigeng Zhou",
                "org": "Fudan University(Fudan University),Shanghai,China"
            }
        ],
        "venue": "Journal of Organometallic Chemistry",
        "year": 2003
    },
    "M5O00WYG": {
        "id": "M5O00WYG",
        "title": "Insertion of carbodiimide into the LnN σ-bond of organolanthanide complexes. Synthesis and characterization of organolanthanide guanidinates (C 5 H 5 ) 2 Ln[ i PrNC(N i Pr 2 )∴N i Pr] (Ln=Yb, Dy, Gd)",
        "abstract": "",
        "keywords": [
            "cyclopentadienyl",
            "insertion",
            "mass spectroscopy",
            "single crystal",
            "structures"
        ],
        "authors": [
            {
                "name": "jie zhang",
                "org": "fudan university"
            },
            {
                "name": "ruifang cai",
                "org": "fudan university"
            },
            {
                "name": "linhong weng",
                "org": "fudan university"
            },
            {
                "name": "xigeng zhou",
                "org": "fudan university"
            }
        ],
        "venue": "Journal of Organometallic Chemistry",
        "year": 2003
    },
    "PE5ikoI1": {
        "id": "PE5ikoI1",
        "title": "Insertion of a carbodiimide into the Ln-N σ-bond of organolanthanide complexes. Isomerization and rearrangement of organolanthanides containing guanidinate ligands",
        "abstract": "The reaction of (C5H5)YCl2(THF) 3 with LiNiPr2 and subsequently with 2 equiv of N,Ń-diisopropylcarbodiimide (iPrN=C=NiPr) in THF gave the organoyttrium guanidinates Y[iPrNC(NiPr 2)NiPr]3 (1) and (C5H 5)2Y[iPrNC(NiPr2)N iPr] (2), which may be rationalized by the rearrangement reaction of the diinsertion product (C5H5)Y[iPrNC(N iPr2)N'Pr]2. Treatment of iPrN-C=N iPr with lanthanocene primary amides [(C5H 5)2LnNHR]2 (R = tBu, Ln = Yb, Er, Dy, Y; R = Ph, Ln = Yb) gave the unexpected products (C5H 5)2Yb[RNC(NHiPr)NiPr] (R = tBu, Ln = Yb (3), Er (4), Dy (5), Y(6); R = Ph, Ln = Yb (7)), indicating that a novel isomerization reaction involving a 1,3-hydrogen shift takes place along with the insertion of carbodiimide into the Ln-N a-bond, which provides an efficient synthesis of organolanthanide complexes with asymmetrical guanidinate ligands. All these complexes were characterized by elemental analysis and spectroscopic properties. The structures of complexes 1-5 and 7 were also determined by X-ray diffraction analysis.",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Ruifang Cai",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Linhong Weng",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Xigeng Zhou",
                "org": "Fudan University(Fudan University),Shanghai,China"
            }
        ],
        "venue": "Organometallics",
        "year": 2004
    },
    "ilR0iqQv": {
        "id": "ilR0iqQv",
        "title": "Syntheses, structures and magnetic properties of two novel 3D helical dicyanamide complexes containing polyamine ligand",
        "abstract": "",
        "keywords": [
            "crystal structure",
            "ir spectra",
            "crystal structures",
            "magnetic properties"
        ],
        "authors": [
            {
                "name": "chunmei zhang",
                "org": "fudan university"
            },
            {
                "name": "ruifang cai",
                "org": "fudan university"
            },
            {
                "name": "linhong weng",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": "fudan university"
            },
            {
                "name": "song gao",
                "org": "fudan university"
            },
            {
                "name": "xigeng zhou",
                "org": "fudan university"
            },
            {
                "name": "yanrong li",
                "org": "fudan university"
            },
            {
                "name": "zehuai shao",
                "org": "fudan university"
            },
            {
                "name": "jun luo",
                "org": "fudan university"
            }
        ],
        "venue": "Inorganic Chemistry Communications",
        "year": 2004
    },
    "58R3ekWf": {
        "id": "58R3ekWf",
        "title": "Modification of mesoporous silicate SBA-15 with tris[bis(trimethylsilyl)amido]samarium and its utility in Tishchenko reaction",
        "abstract": "Treatment of mesoporous silicate SBA-15 with Sm[N(SiMe 3 ) 2 ] 3 led to the formation of a novel organolanthanide/inorganic hybrid material [SBA-15]Sm[N(SiMe 3 ) 2 ] x via abstraction of N(SiMe 3 ) 2 by terminal silanol groups and subsequent surface silylation. The hybrid material was characterized by elemental analyses, IR spectroscopy, X-ray diffraction, and nitrogen sorption, indicating a successful tailoring inside the silicate SBA-15 and the maintenance of the well-ordered mesostructure. This hybrid material is a promising heterogeneous catalyst for the Tishchenko reaction, where it is superior to the homogeneous correspondent in deactivation behavior, reusability and relative tolerance to oxygen, particularly in the control of selectivity of mixed Tishchenko reaction due to the steric hindrance and the diffusion control derived from the surface confinement.",
        "keywords": [
            "sba-15",
            "organolanthanide",
            "immobilization",
            "tishchenko reaction",
            "hybrid material",
            "nitrogen",
            "x ray diffraction",
            "ir spectroscopy"
        ],
        "authors": [
            {
                "name": "Yinghua Chen",
                "org": "Department of Chemistry, Molecular Catalysis and Innovative, Material Laboratory, Fudan University, Handan Road 220, Shanghai 200433, People’s Republic of China"
            },
            {
                "name": "Zhenyu Zhu",
                "org": "Department of Chemistry, Molecular Catalysis and Innovative, Material Laboratory, Fudan University, Handan Road 220, Shanghai 200433, People’s Republic of China"
            },
            {
                "name": "Jie Zhang",
                "org": "Department of Chemistry, Molecular Catalysis and Innovative, Material Laboratory, Fudan University, Handan Road 220, Shanghai 200433, People’s Republic of China"
            },
            {
                "name": "Jianzhong Shen",
                "org": "Department of Chemistry, Molecular Catalysis and Innovative, Material Laboratory, Fudan University, Handan Road 220, Shanghai 200433, People’s Republic of China"
            },
            {
                "name": "Xigeng Zhou",
                "org": ""
            }
        ],
        "venue": "Journal of Organometallic Chemistry",
        "year": 2005
    },
    "yLEtoLG2": {
        "id": "yLEtoLG2",
        "title": "Substituent effects on isocyanate insertion into a lanthanide-sulfur bond. unexpected construction of a coordinated thiazolate ring",
        "abstract": "[Cp2Yb(o-H2NC6H4S)] 2·2THF (1) and Cp2Yb(p-H2NC 6H4S)(THF) (2) were prepared in good yields by the protonolysis of Cp3Yb with the corresponding amino-substituted thiophenol in THF at room temperature, respectively. Treatment of [Cp 2Yb(o-H2NC6H4S)]2· 2THF (1) with PhNCO gives the unexpected intermolecular addition/cyclization/ elimination product [(C5H5)2- Yb(μ-η1:η3-OSNC7H4)] 2 (3), while Cp2Yb(p-H2NC6H 4S)(THF) (2) reacts with PhNCO under the same conditions to form the simple insertion product {Cp2Yb[μ-η1: η3-OC(p-H2NC6H4S)NPh]} 2·2THF (4), demonstrating that the neighboring NH2 group participation could lead to unique isocyanate insertion reactivity. The structures of all the complexes were confirmed by X-ray single-crystal diffraction analysis, indicating that complexes 1 and 4 have an unusual intermolecular hydrogen bond interaction involving THF, and a novel intramolecular π-π weak interaction between aromatic rings is also observed in 4.",
        "keywords": [],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Liping Ma",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Ruifang Cai",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Linhong Weng",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Xigeng Zhou",
                "org": "Fudan University(Fudan University),Shanghai,China"
            }
        ],
        "venue": "Organometallics",
        "year": 2005
    },
    "ZCCNwOlh": {
        "id": "ZCCNwOlh",
        "title": "Reactivity of organolanthanide and organolithium complexes containing the guanidinate ligands toward isocyanate or carbodiimide: synthesis and crystal structures.",
        "abstract": "The direct reactions of (C5H5)2LnCl with LiN=C(NMe2)2 proceeded at room temperature in THF under pure nitrogen to yield the lanthanocene guanidinate complexes [(C5H5)2Ln(mu-eta1:eta2-N=C(NMe2)2)]2 (Ln = Gd (1), Er (2)). Treatment of phenyl isocyanate with complexes 1 and 2 results in monoinsertion of phenyl isocyanate into the Ln-N(mu-Gua) bond to yield the corresponding insertion products [(C5H5)2Ln(mu-eta1:eta2-OC(N=C(NMe2)2)NPh)]2 (Ln = Gd (3), Er (4)), presenting the first example of unsaturated organic small molecule insertion into the metal-guanidinate ligand bond. Further investigations indicate that N,N'-diisopropylcarbodiimide does not react with complexes 1 and 2 under the same conditions; however, it readily inserts into the lithium-guanidinate ligand bond of LiN=C(NMe2)2. As a synthon of the insertion product Li[(iPrN)2C(N=C(NMe2)2)], its reaction with (C5H5)2LnCl gives the novel organolanthanide complexes containing the guanidinoacetamidinate ligand, (C5H5)2Ln[(iPrN)2C(N=C(NMe2)2)] (Ln = Yb (5), Er (6), Dy (7)). All complexes were characterized by elemental analysis and spectroscopic properties. The structures of complexes 1, 3, 5 and 7 were determined through X-ray single-crystal diffraction analysis.",
        "keywords": [
            "crystal structure"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Xigeng Zhou",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Ruifang Cai",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Linhong Weng",
                "org": "Fudan University(Fudan University),Shanghai,China"
            }
        ],
        "venue": "Inorganic chemistry",
        "year": 2005
    },
    "EqAcro1l": {
        "id": "EqAcro1l",
        "title": "Facile Transformations of Lanthanocene Alkyls to Lanthanocene Thiolate, Sulfide, and Disulfide Derivatives by Reaction with Elemental Sulfur",
        "abstract": "",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Yanrong Li",
                "org": ""
            },
            {
                "name": "Chengfu Pi",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Xigeng Zhou",
                "org": ""
            },
            {
                "name": "Zhenxia Chen",
                "org": ""
            },
            {
                "name": "Linhong Weng",
                "org": ""
            }
        ],
        "venue": "Organometallics",
        "year": 2005
    },
    "RRbb8mWr": {
        "id": "RRbb8mWr",
        "title": "Synthesis and reactivity of organolanthanide complexes containing phenothiazine ligand toward carbodiimide and isothiocyanate",
        "abstract": "The synthesis and reactivity of new lanthanocene complexes incorporating phenothiazine ligand are described. The reaction of phenothiazine (HPtz) with n BuLi in THF and subsequently with 1 equiv. of (C 5 H 5 ) 2 LnCl(THF) gave the original complexes (C 5 H 5 ) 2 LnPtz(THF) (Ln = Yb( 1 ), Er( 2 ), Dy( 3 ), Y( 4 )). Treatment of complexes 1 – 4 with N , N ′-diisopropylcarbodiimide results in mono-insertion of carbodiimide into the Ln–N(Ptz)-bond to yield the corresponding guanidinates (C 5 H 5 ) 2 Ln[( i PrN) 2 C(Ptz)] (Ln = Yb ( 5 ), Er ( 6 ), Dy ( 7 ), Y( 8 )). Further investigations indicate that phenyl isothiocyanate react with complexes 1 and 4 , giving the correspondent insertion products (C 5 H 5 ) 2 Ln[SC(Ptz)NPh](THF) (Ln = Yb( 9 ), Y( 10 )). All these complexes were characterized by elemental analysis and spectroscopic properties. The structures of complexes 2 , 5 and 9 were also determined by the X-ray single crystal diffraction analysis. All these reactions provide a new strategy for introducing a functional substituent at the nitrogen atom of phenothiazine via forming a new C–N(ring) bond. Keywords Organolanthanide Insertion Phenothiazine Carbodiimide Isothiocyanate 1 Introduction Phenothiazines and Substituted phenothiazines are important biologically active heterocyclic compounds in which nitrogen and sulfur are incorporated in the tricyclic system. They are versatile compounds possessing anticholinergic, antihistamine, and antiemetic activities [1] . The coordination chemistry of metal ions with phenothiazine has been extensively investigated [2] , and confirmed that phenothiazine–metal coordination complexes generally increased their antimutagenic activity, compared to their parent compounds. Recently, the coordination complexes of lanthanide nitrates with promethazine have also been reported [3] . Our recent research interests are in investigating the activity of the lanthanide–ligand bonds of organolanthanide derivates [4] . In the previous work, we studied the reactivity of some organolanthanide complexes containing the aromatic N-heterocyclic ligands toward carbodiimide, isocyanate or isothiocyanate [5] . The accumulated information indicates that the occurrence of the insertion strongly depends on the degree of the steric saturation around the center metal ion and the nature of the ligands. Continuing our recent investigation of the lanthanide–ligand insertion and learning more about the phenothiazine anion as a ligand, we herein report the synthesis of the organolanthanide phenothiazine complexes as well as their reactivity with carbodiimide and isothiocyanate, which provide an alternative strategy for introducing a functional substituent at the nitrogen atom of phenothiazine via forming a new C–N(ring) bond. 2 Results and discussion 2.1 Synthesis and characterization of lanthanocene phenothiazine complexes (C 5 H 5 ) 2 LnPtz(THF) (Ln = Yb( 1 ), Er( 2 ), Dy( 3 ), Y( 4 )) Lanthanocene amides are important organolanthanide complexes, and their synthesis and reactivity have received much attention. The metathesis and metalation reactions are the main routes for preparation of these complexes [6] . Here, we synthesized these organolanthanide phenothiazine complexes (C 5 H 5 ) 2 LnPtz(THF) (Ln = Yb( 1 ), Er( 2 ), Dy( 3 ), Y( 4 )) by the metathesis reaction of (C 5 H 5 ) 2 LnCl(THF) with 1 equiv. of LiPtz in THF at room temperature, as shown in the following reaction equation (1) Complexes 1 – 4 are air- and moisture-sensitive. They are soluble in THF and toluene and slightly soluble in n -hexane. Complexes 1 – 4 have been characterized by elemental analysis, IR and mass spectroscopy or 1 H NMR. In the IR spectra, complexes 1 – 4 exhibit two characterized absorptions at 1580 and 1560 cm −1 , which are attributed to the phenothiazine ligand, and two well-defined bands at 1070 and 880 cm −1 for the coordinated THF. The 1 H NMR of complex 4 also reveals that the solvent molecule THF is coordinated with the centre metal ion Y 3+ in the solution. The crystal structure of 2 has been determinated by X-ray single crystal diffraction analysis. It also is the first crystallographically confirmed rare earth metal–phenothiazine compound. 2 Crystallized from the mixture solvent of THF and n -hexane at −20 °C in the monoclinic system, space group P 2 1 / n . The molecular structure of 2 is shown in Fig. 1 . Selected bond lengths and angles are given in Table 1 . Complex 2 is solvent monomer. The erbium atom is carried two η 5 -cyclopentadienyl rings, one η 1 -phenothiazine ligand and one coordinated THF. The coordination number of the central metal Er 3+ is eight. The Er(1)–N(1) and Er(1)–O(1) distances (2.291(5), 2.349(5) Å) are in the normal ranges [7] . The Er–C(Cp) distances range from 2.622(7) to 2.663(8) Å. The average value of 2.639(7) Å is similar to those found in other trivalent lanthanide complexes, such as [Li(THF) 4 ]{[(C 5 H 5 ) 2 ErH] 3 Cl}, 2.65 Å [8a] and (C 5 H 5 )ErCl 2 (THF) 3 , 2.667 Å [8b] . 2.2 Insertion of N,N′-diisopropylcarbodiimide into the Ln–N bond of complexes 1 – 4 Our recently investigations have indicated that carbodiimide readily insert into the Ln–C or Ln–N-bonds of organolanthanide derivates, yielding the corresponding amidinate or guanidinate complexes [4c,4d,4e,5] . They provide an efficient method to synthesize the organolanthanide amidinate and guanidinate complexes. In order to study the effect of the nature of the organic nitrogen ligand on the insertion and explore the reactivity of complexes 1 – 4 , we first investigate the reaction of 1 – 4 with N ,N′-diisopropylcarbodiimide. As shown in Scheme 1 , when i PrN C N i Pr was added to a THF solution of 1 – 4 at room temperature, respectively, the corresponding guanidinate complexes (C 5 H 5 ) 2 Yb[( i PrN) 2 C(Ptz)] (Ln = Yb( 5 ), Er( 6 ), Dy( 7 ), Y( 8 )) were obtained in moderate yield, indicating that one carbodiimide molecule is inserted into the Ln–N(Ptz) bond. The mass spectra of complexes 5 – 8 display the molecular ion peaks and the insertion fragments of [( i PrN) 2 C(Ptz)]. In IR spectra of these guanidinates, the characterized absorption at ca. 2100 cm −1 for the ν as (N C N) stretch of free carbodiimide is absent, but a new strong band at ca. 1660 cm −1 attributable to the delocalized –NCN– stretching mode is present [9] . The formation of the new ligand [( i PrN) 2 C(Ptz)] and solvent-free monomer structure of 8 have also been confirmed by the 1 H NMR. Complex 5 was further confirmed by the X-ray single crystal structural determination. The X-ray structure analysis results show that 5 ( Fig. 2 , Table 2 ) is a solvent-free monomer with the lanthanide atom bonded to two η 5 -cyclopentadienyl rings and one chelating guanidinate ligand to form distorted tetrahedron geometry. As expected, the coordinated guanidinate group forms essentially a planar four-membered ring with the lanthanide atom within experimental errors. The bond angles around C(11) are consistent with sp 2 hybridization. The cent-Ln-cent (cent = the center of cyclopentadienyl ring) plane relative to the NCNLn plane is approximately perpendicular (88.6°). The C(11)–N(1) and C(11)–N(2) distances of the guanidinate group are approximately equivalent and significantly shorter than the C–N single bond distances, indicating that the π-electrons of the C N double bond in the present structure are delocalized over the N–C–N unit [10] . Consistent with this observation, the Yb–N(1) and Yb–N(2) distances, 2.304(6) and 2.307(7) Å, are intermediate between the values observed for an Yb–N single bond distance and an Yb–N donor bond distances (2.19–2.69 Å) [9,11] , and are comparable to the corresponding values found in (C 5 H 5 ) 2 Yb[( i PrN) 2 C(Cbz)] (Cbz = carbazolate) (Yb–Nav = 2.299(6) Å) [5] . The Yb–C(Cp) distances range from 2.570(11) to 2.600(10) Å, and are in the normal ranges observed for lanthanocene complexes. The average Yb–C(Cp) distance of 2.584(12) Å is similar to those found in other Cp 2 Yb-containing compounds, such as (C 5 H 5 ) 2 Yb(PzMe 2 )(HPzMe 2 ), 2.62(1) Å; [6j] [(C 5 H 5 ) 2 Yb(OCMe C CHMe)] 2 , 2.63(1) Å; [12b] (C 5 H 5 ) 2 Yb(CH 3 )(THF), 2.60(2) Å [12a] . 2.3 Reactions of complexes 1 and 4 with phenyl isothiocyanate In order to gain more insight into the reactivity of complexes 1 and 4 , the reactions of 1 and 4 with phenyl isothiocyanate were also studied. It is found that reaction of complexes 1 and 4 with 1 equiv. of phenyl isothiocyanate result in the formation of the insertion product (C 5 H 5 ) 2 Ln[SC(Ptz)NPh](THF) (Ln = Yb( 9 ), Y( 10 )), respectively ( Scheme 2 ). These compounds have been characterized by standard spectroscopic and analytical techniques. The structure of 9 has also been determinated by X-ray single crystal analysis. X-ray determination indicates that complex 9 has a solvent monomer structure, as shown in Fig. 3 , in which (C 5 H 5 ) 2 Yb fragment connects with one [SC(Ptz))NPh] − unit and one THF molecule. Its coordination geometry is similar to that in complex (C 5 H 5 )Yb(SC(Cbz)NPh) 2 (THF) [5] . Selected bond distances and angles are given in Table 3 . The N(1)–C(17) and S(1)–C(17) bond lengths, 1.327(7) and 1.725(6) Å, are in intermediate values between the corresponding C–N and C–S single- and double-bond distances [13] . These bond parameters indicate substantial electronic delocalization over the S–C–N unit [14] . Consistent with this, the observed Yb–N(1) (2.449(5) Å) bond distance is in agreement with that of the Yb–N(1) (2.515(3) Å) in (C 5 H 5 )Yb(SC(Cbz)NPh) 2 (THF). The Yb(1)–S(1) distance of 2.733(4) Å in 9 is comparable to the corresponding values found in [(CH 3 C 5 H 4 ) 2 Y(SC(NPh 2 )NPh)] 2 (Y–S 2.988(8) Å) [14] , if the difference in ionic radii is considered [15] . Significantly, the distance of N(2)–C(17) (1.395(7) Å) in 9 is shorter than the corresponding value found in 5 (N(3)–C(14) 1.454(10) Å), which maybe indicted that the lone pair electrons of the N(2) atom partially delocalized on the S–C–N unit. The Yb–C(Cp) distances in complex 9 are the normal ranges observed for yetterbocene complexes [13] . 3 Conclusion We synthesized four new organolanthanide complexes containing the phenothiazine ligand and investigated the reactivity of them toward carbodiimide or isothiocyanate. These results indicate that N , N ′-diisopropylcarbodiimide readily mono-insert into the lanthanide–nitrogen bonds of them under mild conditions, giving the corresponding guanidinates. Further study reveals phenyl isothiocyanate also react with complexes 1 and 4 to yield the insertion products. All the reactions provide an alternative synthetic strategy for the modification of the phenothiazine ligand. 3.1 Experimental 3.1.1 General procedure All operations involving air- and moisture-sensitive compounds were carried out under an inert atmosphere of purified argon or nitrogen using standard Schlenk techniques. The solvents of THF, toluene, n -hexane were refluxed and distilled over sodium benzophenone ketyl under nitrogen immediately prior to use. (C 5 H 5 ) 2 LnCl(THF) were prepared by the literature procedure [16] . Phenothiazine, N , N ′-diisopropylcarbodiimide and phenyl isothiocyanate were purchased from Aldrich and were used without purification. Elemental analyses for C, H and N were carried out on a Rapid CHN-O analyzer. Infrared spectra were obtained on a NICOLET FT-IR 360 spectrometer with samples prepared as Nujol mulls. Mass spectra were recorded on a Philips HP5989A instrument operating in EI mode. Crystalline samples of the respective complexes were rapidly introduced by the direct inlet techniques with a source temperature of 200 °C. The values of m / z refer to the isotopes 12 C, 1 H, 14 N, 16 O, 89 Y, 164 Dy, 166 Er and 174 Yb. 1 H NMR data were obtained on a Bruker DMX-500 NMR spectrometer and were referenced to residual aryl protons in C 6 H 6 ( δ 7.16). 3.1.2 Synthesis of (C 5 H 5 ) 2 YbPtz(THF) ( 1 ) A solution of n BuLi (1.60 M, 1.10 mL in cyclohexane) was added dropwise to a 20 ml THF solution of HPtz (0.350 g, 1.76 mmol) at −30 °C. After stirred for 30 min at the low temperature, the mixture solution was slowly warmed to room temperature and stirred for 3 h. The reaction mixture was slowly added dropwise to the THF solution of Cp 2 YbCl (0.598 g, 1.76 mmol) at room temperature and the solution color soon turned from orange to dark green. After stirring for 12 h, the solvent was removed under vacuum and the solid residue was extracted with 30 ml toluene. The extract solution was concentrated and cooled at −20 °C to give dark green powder. Recrystallization of the powder from the mixture solvent of THF and toluene gave 1 as dark green crystals. Yield: 0.788 g (78%). Anal. Calc. for C 26 H 26 NOSYb, M w = 573.61: C, 54.44; H, 4.57; N, 2.44. Found: C, 54.37; H, 4.51; N, 2.50%. IR (Nujol, cm −1 ): 3545 w, 3339 w, 1582 s, 1560 s, 1440 s, 1429 s, 1288 s, 1228 s, 1211 s, 1074 m, 1010 s, 934 m, 875 m, 844 s, 780 s, 757 s, 665 w. EI-MS: m / z [fragment, relative intensity (%)] = 502 (M − THF, 98), 304 (M − THF − L, 84), 199 (L + H, 100), 65 (Cp, 10) [L = Ptz]. 3.1.3 Synthesis of (C 5 H 5 ) 2 ErPtz(THF) ( 2 ) n BuLi (1.60 M, 0.90 mL in cyclohexane) was added to a solution of HPtz (0.306 g, 1.54 mmol) in 30 ml THF at −30 °C. After being stirred for 3 h, the mixture solution was added to the THF solution of Cp 2 ErCl (0.510 g, 1.54 mmol) at room temperature. The reaction mixture was subsequently worked up by the method described above. Pink crystals of 2 were obtained in 72% yield, 0.629 g. Anal. Calc. for C 26 H 26 NOSEr, M w = 567.80: C, 55.00; H, 4.62; N, 2.47. Found: C, 54.91; H, 4.60; N, 2.52%. IR (Nujol, cm −1 ): 3550 w, 3341 w, 1582 s, 11562 s, 1441 s, 1428 s, 1291 s, 1231 s, 1214 s, 1070 m, 1009 s, 934 w, 890 m, 843 s, 785 s, 756 s. EI-MS: m / z [fragment, relative intensity (%)] = 494 (M − THF, 55), 296 (M − THF − L, 100), 199 (L + H, 61), 65 (Cp, 16) [L = Ptz]. 3.1.4 Synthesis of (C 5 H 5 ) 2 DyPtz(THF) ( 3 ) Following the procedure described for 1 , reaction of HPtz (0.382 g, 1.92 mmol) with n BuLi (1.60 M, 1.20 mL in cyclohexane) and subsequently with Cp 2 DyCl (0.633 g, 1.92 mmol) gave 3 as pale yellow crystals. Yield: 0.736 g (68%). Anal. Calc. for C 26 H 26 NOSDy, M w = 563.07: C, 55.46; H, 4.65; N, 2.49. Found: C, 55.42; H, 4.60; N, 2.54%. IR (Nujol, cm −1 ): 3551 w, 3342 w, 1584 s, 1561 s, 1442 s, 1429 s, 1292 s, 1231 s, 1212 s, 1074 m, 1010 s, 933 w, 878 m, 847 s, 783 s, 759 s. EI-MS: m / z [fragment, relative intensity (%)] = 492 (M − THF, 13), 294 (M − THF − L, 100), 199 (L + H, 36), 65 (Cp, 12) [L = Ptz]. 3.1.5 Synthesis of (C 5 H 5 ) 2 YPtz(THF) ( 4 ) Following the procedure described for 1 , reaction of HPtz (0.244 g, 1.23 mmol) with n BuLi (1.60 M, 0.62 mL in cyclohexane) and subsequently with Cp 2 YCl (0.312 g, 1.23 mmol) gave 4 as pale yellow crystals. Yield: 0.433 g (72%). Anal. Calc. for C 26 H 26 NOSY, M w = 489.48: C, 63.80; H, 5.35; N, 2.86. Found: C, 63.71; H, 5.37; N, 2.84%. IR (Nujol, cm −1 ): 3555 w, 3340 w, 1597 s, 1572 s, 1444 s, 11342 s, 1313 s, 1244 s, 1070 m, 1011 s, 926 w, 860 m, 847 s, 793 s, 753 s, 664 w. 1 H NMR: δ 6.56–6.85 (m, 8H, C 12 H 8 NS), 6.10 (s, 10H, C 5 H 5 ), 3.57 (m, 4H, O(C H 2 ) 2 (CH 2 ) 2 ), 1.41 (m, 4H, O(CH 2 ) 2 (C H 2 ) 2 ). EI-MS: m / z [fragment, relative intensity (%)] = 417 (M − THF, 43), 219 (M − THF − L, 67), 199 (L + H, 100), 65 (Cp, 26) [L = Ptz]. 3.1.6 Synthesis of (C 5 H 5 ) 2 Yb[( i PrN) 2 C(Ptz)] ( 5 ) To a 30 mL THF solution of 1 (0.645 g, 1.12 mmol), N , N ′-diisopropylcarbodiimide (0.141 g, 1.12 mmol) was slowly added dropwise at room temperature and stirred for several hours. The dark green solution became yellow-orange. After stirring for overnight, the reaction solution was concentrated by reduced pressure to about 2 mL. Addition of 20 mL of n -hexane resulted in the precipitation of a yellow solid. The resulting mixture was centrifuged, and the solution decanted. The precipitate was dried under vacuum to afford a yellow power. Recrystallization of the powder from the mixture solvent of THF and n -hexane gave 4 as yellow crystals. Yield: 0.457 g (65%). Anal. Calc. for C 29 H 32 N 3 SYb, M w = 627.68: C, 55.49; H, 5.14; N, 6.69. Found: C, 55.44; H, 5.10; N, 6.77. IR (Nujol, cm −1 ): 3366 w, 1663 s, 1597s, 1573 s, 1312 m, 1245 s, 1172 m, 1093 s, 1014 s, 971 s, 772 s, 741 s, 663 w. EI-MS: m / z [fragment, relative intensity (%)] = 628 (M, 5), 502 (M − i PrNCN i Pr, 19), 334 (L, 46), 304 (Cp 2 Yb, 11), 199 (Ptz + H, 20), 65 (Cp, 9) [L = ( i PrN) 2 C(Ptz)]. 3.1.7 Synthesis of (C 5 H 5 ) 2 Er[( i PrN) 2 C(Ptz)] ( 6 ) Following the procedure described for 4 , reaction of 2 (0.534 g, 0.94 mmol) with N , N ′-diisopropylcarbodiimide (0.119 g, 0.94 mmol) gave 5 as pink crystals. Yield: 0.433 g (74%). Anal. Calc. for C 29 H 32 N 3 Ser, M w = 621.92: C, 56.01; H, 5.19; N, 6.76. Found: C, 55.93; H, 5.10; N, 6.81%. IR (Nujol, cm −1 ): 3363 w, 1660 s, 1591s, 1572 s, 1313 m, 1255 s, 1172 m, 1093 s, 1013 s, 924 w, 772 s, 741 s, 658 w. EI-MS: m / z [fragment, relative intensity (%)] = 496 (M − i PrNCN i Pr, 66), 422 (M − Ptz, 40), 296 (Cp 2 Er, 100), 199 (Ptz + H, 52), 66 (Cp + H, 15) [L = ( i PrN) 2 C(Ptz)]. 3.1.8 Synthesis of (C 5 H 5 ) 2 Dy[( i PrN) 2 C(Ptz)] ( 7 ) Following the procedure described for 4 , reaction of 3 (0.574 g, 1.02 mmol) with N , N ′-diisopropylcarbodiimide (0.129 g, 1.02 mmol) gave 6 as pale yellow crystals. Yield: 0.415 g (66%). Anal. Calc. for C 29 H 32 N 3 SDy, M w = 617.16: C, 56.44; H, 5.23; N, 6.81. Found: C, 56.38; H, 5.26; N, 6.88%. IR (Nujol, cm −1 ): 3365 w, 1660 s, 1594s, 1572 s, 1316 m, 1244 s, 1168 m, 1094 s, 1009 s, 952 s, 770 s, 736 s, 684 w. EI-MS: m / z [fragment, relative intensity (%)] = 618 (M, 7), 492 (M − i PrNCN i Pr, 91), 420 (M − Ptz, 36), 294 (Cp 2 Dy, 100), 198 (Ptz, 50), 65 (Cp, 10) [L = ( i PrN) 2 C(Ptz)]. 3.1.9 Synthesis of (C 5 H 5 ) 2 Y[( i PrN) 2 C(Ptz)] ( 8 ) Following the procedure described for 5 , reaction of 4 (0.764 g, 1.56 mmol) with N , N ′-diisopropylcarbodiimide (0.197 g, 1.56 mmol) gave 8 as pale yellow crystals. Yield: 0.534 g (63%). Anal. Calc. for C 29 H 32 N 3 SY, M w = 543.57: C, 64.08; H, 5.93; N, 7.73. Found: C, 63.95; H, 5.86; N, 7.88%. IR (Nujol, cm −1 ): 3399 w, 1659 s, 1595s, 1573 w, 1506 s, 1389 s, 1340 s, 1317s, 1203 m, 1094 s, 1011 s, 953 s, 774 s, 740 s, 681 w. 1 H NMR: δ 6.49–6.76 (m, 8H, C 12 H 8 NS), 6.20 (s, 10H, C 5 H 5 ), 4.06 (m, 1H, CH 3 C H CH 3 ), 3.88 (m, 1H, CH 3 C H CH 3 ), 1.13 (b, 6H, C H 3 CHC H 3 ), 0.96 (b, 6H, C H 3 CHC H 3 ). EI-MS: m / z [fragment, relative intensity (%)] = 543 (M, 44), 417 (M − i PrNCN i Pr, 39), 334 (L, 57), 219 (Cp 2 Y, 61), 199 (Ptz + H, 23), 65 (Cp, 13) [L = ( i PrN) 2 C(Ptz)]. 3.1.10 Synthesis of (C 5 H 5 ) 2 Yb[SC(Ptz)NPh](THF) ( 9 ) To a 20 mL THF solution of 1 (0.711 g, 1.24 mmol), phenyl isocyanate (0.156 g, 1.24 mmol) was slowly added dropwise at −30 °C. After stirred for 30 min at the low temperature, the mixture solution was slowly warmed to room temperature and stirred for several hours. All volatile substances were removed under vacuum to give a yellow powder. Further crystallization by diffusion of n -hexane into the above solution yielded the yellow crystals 7 . Yield: 0.492 g (56%). Anal. Calc. for C 33 H 31 N 2 OS 2 Yb, M w = 708.76: C, 55.92; H, 4.41; N, 3.95. Found: C, 55.89; H, 4.37; N, 3.96%. IR (Nujol, cm −1 ): 3358 w, 1587 s, 1302 m, 1277 s, 1248 s, 1197 m, 1152 s, 1068 s, 1015 s, 898 m, 869 m, 781 s, 759 s, 690 s, 669 w. EI-MS: m / z [fragment, relative intensity (%)] = 637 (M − THF, 4), 502 (M − THF − PhNCS, 49), 439 (M − THF − Ptz, 2), 304 (Cp 2 Yb, 41), 199 (Ptz + H, 85), 135 (PhNCS, 65), 72 (THF, 50), 65 (Cp, 13). 3.1.11 Synthesis of (C 5 H 5 ) 2 Y[SC(Ptz)NPh](THF) ( 10 ) Following the procedure described for 5 , reaction of 4 (0.690 g, 1.41 mmol) with phenyl isothiocyanate (0.168 g, 1.41 mmol) gave 10 as pale yellow crystals. Yield: 0.590 g (67%). Anal. Calc. for C 33 H 31 N 2 OS 2 Y, M w = 624.67: C, 63.45; H, 5.00; N, 4.48. Found: C, 63.37; H, 4.93; N, 4.54%. IR (Nujol, cm −1 ): 3361 w, 3340 w, 1591 s, 1510w, 1361 m, 1279 m, 1250 s, 1142 s, 1069 s, 1016 s, 897 m, 869 m, 760 s, 690 s, 664 w. 1 H NMR: δ 7.00–7.60 (m, 5H, C 6 H 5 ), 6.50–6.89 (m, 8H, C 12 H 8 NS), 3.55 (m, 4H, O(C H 2 ) 2 (CH 2 ) 2 ), 1.37 (m, 4H, O(CH 2 ) 2 (C H 2 ) 2 ). EI-MS: m / z [fragment, relative intensity (%)] = 552 (M − THF, 23), 417 (M − THF − PhNCS, 34), 229 (Cp 2 Y, 56), 199 (Ptz + H, 100), 135 (PhNCS, 89), 72 (THF, 68), 65 (Cp, 24). 3.1.12 X-ray data collection, structure determination and refinement Suitable single crystals of complexes 2 , 5 and 9 were sealed under argon in Lindemann glass capillaries for X-ray structural analysis. Diffraction data were collected on a Bruker SMART Apex CCD diffractometer using graphite-monochromated Mo Kα ( λ = 0.71073 Å) radiation. During the intensity data collection, no significant decay was observed. The intensities were corrected for Lorentz-polarization effects and empirical absorption with sadabs program [17] . The structures were solved by the direct method using the shelxl -97 program [18] . All non-hydrogen atoms were found from the difference Fourier syntheses. The H atoms were included in calculated positions with isotropic thermal parameters related to those of the supporting carbon atoms, but were not included in the refinement. All calculations were performed using the Bruker SMART program. A summary of the crystallographic data and selected experimental information is given in Table 4 . 4 Supplementary data Crystallographic data (excluding structure factors) for the structures reported in this paper have been deposited with the Cambridge Crystallographic Data Centre as supplementary Publication Nos. CCDC-272484 ( 2 ), CCDC-272485 ( 5 ), and CCDC-272486 ( 9 ). Copies of the data can be obtained free of charge on application to CCDC, 12 Union Road, Cambridge CB21EZ, UK (fax: +44 1223 336 033: e-mail: deposit@ccdc.cam.ac.uk ). Acknowledgments We thank the National Natural Science Foundation of China and the Research Funds of Young Teacher of Fudan University for financial support. References [1] A.R. Katritzky A.J. Boulton Advances in Heterocyclic Chemistry vol. 9 1968 Academic Press New York p. 336 [2] (a) B. Keshavan J. Seetharamappa Polyhedron 6 1987 465 (b) R. Kroener M.J. Heeg E. Deutsch Inorg. Chem. 27 1988 558 (c) N.M. Made Gowda L. Zhang Synth. React. Inorg. Met–Org. Chem. 24 1994 831 (d) N.M. Made Gowda R.K. Vallabhaneni I. Gajula S. Ananda J. Mol. Struct. 407 1997 125 (e) B. Keshavan H. Ramalingaiah Transit. Met. Chem. 22 1997 185 (f) B.J. Coe J.A. Harris L.J. Harrington J.C. Jeffery L.H. Rees S. Houbrechts A. Persoons Inorg. Chem. 37 1998 3391 (g) X. Zhang Y. Xie W. Yu Q. Zhao M. Jiang Y. Tian Inorg. Chem. 42 2003 3734 [3] (a) B. Keshavan P.G. Chandrashekara N.M. Made Gowda J. Mol. Struct. 553 2000 193 (b) B. Keshavan P.G. Chandrashekara J. Ind. Chem. Soc. 76 1999 182 [4] (a) J. Zhang X.G. Zhou R.F. Cai L.H. Weng Inorg. Chem. 44 2005 716 (b) J. Zhang L.P. Ma R.F. Cai L.H. Weng X.G. Zhou Organometallics 24 2005 738 (c) J. Zhang R.F. Cai L.H. Weng X.G. Zhou Organometallics 23 2004 3303 (d) J. Zhang R.F. Cai L.H. Weng X.G. Zhou J. Organomet. Chem. 672 2003 94 (e) J. Zhang R.Y. Ruan Z.H. Shao R.F. Cai L.H. Weng X.G. Zhou Organometallics 21 2002 1420 (f) X.G. Zhou L.B. Zhang M. Zhu R.F. Cai L.H. Weng Z.X. Huang Q.J. Wu Organometallics 20 2001 5700 [5] J. Zhang R.F. Cai L.H. Weng X.G. Zhou Organometallics 22 2003 5385 [6] (a) R.E. Maginn S. Manastyrskyj M. Dubeck J. Am. Chem. Soc. 85 1963 672 (b) T.D. Tilley R.A. Andersen Inorg. Chem. 20 1981 3267 (c) J.E. Bercaw D.L. Davies P.T. Wolczanski Organometallics 5 1986 443 (d) K.H. den Hann J.L. de Boer J.H. Teuben A.L. Spek B. Kojic-Prodic G.R. Hays R. Huis Organometallics 5 1986 1726 (e) S.P. Nolan D. Stern T.J. Marks J. Am. Chem. Soc. 111 1989 7844 (f) H. Schumann P.R. Lee J. Loebel Chem. Ber. 122 1989 1897 (g) W.J. Evans R.A. Keyer J.W. Ziller Organometallics 12 1993 2618 (h) M.A. Giardello V.P. Conticello L. Brard M. Sabat A.L. Rheingold C.L. Stern T.J. Marks J. Am. Chem. Soc. 116 1994 10212 (i) L. Mao Q. Shen M. Xue J. Sun Organometallics 15 1997 3711 (j) X.G. Zhou Z.E. Huang R.F. Cai L.B. Zhang L.X. Zhang X.Y. Huang Organometallics 18 1999 4128 [7] H. Schumann P.R. Lee J. Loebel Chem. Ber. 123 1990 1331 [8] (a) W.J. Evans J.H. Meadows A.L. Wayda W.E. Hunter J.L. Atwood J. Am. Chem. Soc. 104 1982 2015 (b) C.S. Day V.W. Day R.D. Ernst S.H. Vollmer Organometallics 1 1982 998 [9] J.D. Wilkins J. Organomet. Chem. 80 1974 349 [10] R. Duchateau A. Meetsma J.H. Teuben Organometallics 15 1996 1656 [11] (a) X.G. Zhou Z.E. Huang R.F. Cai L.X. Zhang X.F. Hou X.J. Feng X.Y. Huang J. Organomet. Chem. 563 1998 101 (b) X.G. Zhou H.Z. Ma X.Y. Huang X.Z. You J. Chem. Soc., Chem. Commun. 1995 2483 (c) W.J. Evans D.K. Drummond L.A. Chamberlain R.J. Doeden S.G. Bott H. Zhang J.L. Atwood J. Am. Chem. Soc. 110 1988 4983 [12] (a) W.J. Evans R. Dominguez T.B. Hanusa Organometallics 5 1986 263 (b) X.G. Zhou Z.Z. Wu Z.S. Jin J. Organomet. Chem. 431 1992 289 [13] G. Hafelinger Chem. Ber. 103 1970 2902 [14] H. Li Y. Yao Q. Shen L. Weng Organometallics 21 2002 2529 [15] A. Zalkin T.J. Henly R.A. Anderson Acta Crystallogr Sect. C 43 1987 233 [16] G. Wilkinson J.M. Birmingham J. Am. Chem. Soc. 78 1956 42 [17] G.M. Sheldrick sadabs , A Program for Empirical Absorption Correction 1998 University of Göttingen Germany [18] G.M. Sheldrick shelxl -97, Program for the Refinement of the Crystal Structure 1997 University of Göttingen Germany",
        "keywords": [
            "carbodiimide",
            "insertion",
            "isothiocyanate",
            "organolanthanide",
            "phenothiazine",
            "single crystal",
            "nitrogen"
        ],
        "authors": [
            {
                "name": "Liping Ma",
                "org": "Department of Chemistry, Fudan University, Handan Road 220, Shanghai 200433, People’s Republic of China"
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Ruifang Cai",
                "org": "Department of Chemistry, Fudan University, Handan Road 220, Shanghai 200433, People’s Republic of China"
            },
            {
                "name": "Zhenxia Chen",
                "org": "Department of Chemistry, Fudan University, Handan Road 220, Shanghai 200433, People’s Republic of China"
            },
            {
                "name": "Linhong Weng",
                "org": "Department of Chemistry, Fudan University, Handan Road 220, Shanghai 200433, People’s Republic of China"
            },
            {
                "name": "Xigeng Zhou",
                "org": "Department of Chemistry, Fudan University, Handan Road 220, Shanghai 200433, People’s Republic of China"
            }
        ],
        "venue": "Journal of Organometallic Chemistry",
        "year": 2005
    },
    "xtqhL18Z": {
        "id": "xtqhL18Z",
        "title": "Synthesis and Crystal Structure of a Cocrystalline Compound of a Rare Earth Metalloporphyrin with Fullerene {[TPPYb(μ-OH)2Yb(THF)TPP]·C60}n",
        "abstract": "",
        "keywords": [
            "cocrystal",
            "fullerenes",
            "metalloporphyrin",
            "ytterbium",
            "crystal structure"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Ruifang Cai",
                "org": ""
            },
            {
                "name": "Minqing Chen",
                "org": ""
            },
            {
                "name": "Linhong Weng",
                "org": ""
            },
            {
                "name": "Xigeng Zhou",
                "org": ""
            }
        ],
        "venue": "European Journal of Inorganic Chemistry",
        "year": 2005
    },
    "9zvL5R67": {
        "id": "9zvL5R67",
        "title": "Unusual modification methods for the ureido ligand of lanthanocene derivatives.",
        "abstract": "(C5H5)2Ln[OC(PzMe2)=NPh](THF) (Ln = Dy (1a), Er (1b), Yb (1c), Y (1d)) were prepared in good yields by the PhNCO insertion into the Ln-N bond of (C(5)H(5))(2)Ln(PzMe(2))(THF) (PzMe(2) = 3,5-dimethylpyrazolate) in THF at room temperature. Treatment of with p-aminothiophenol in THF at room temperature gives unusual ligand-based substitution derivatives {(C5H5)2Ln[mu-eta1:eta3-OC(p-H2NC6H4S)NPh]}2.2THF (Ln = Dy (2a), Er (2b), Yb (2c), Y (2d)), while reaction of 1c with o-aminothiophenol instead of p-aminothiophenol allows the occurrence of a tandem substitution/cyclization/elimination to form unexpected benzothiazole-2-oxide complex [(C5H5)2Yb(mu-eta1:eta3-OSNC7H4)]2 (3c), representing a novel modification method for non-cyclopentadienyl ligands of lanthanocene derivatives. However, complex does not react with benzyl thiol, indicating that the nature of thiols has a profound influence on the substitution reaction. All complexes were characterized by elemental analysis and spectroscopic properties. The X-ray diffraction analysis reveals that and are solvated monomeric structures, while and are centrosymmetric dimeric ones with an unusual intermolecular hydrogen bond interaction involving THF.",
        "keywords": [],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Ruifang Cai",
                "org": ""
            },
            {
                "name": "Linhong Weng",
                "org": ""
            },
            {
                "name": "Xigeng Zhou",
                "org": ""
            }
        ],
        "venue": "Dalton transactions (Cambridge, England : 2003)",
        "year": 2006
    },
    "mssO2eyq": {
        "id": "mssO2eyq",
        "title": "Reactivity of lanthanocene hydroxides toward ketene, isocyanate, lanthanocene alkyl, and triscyclopentadienyllanthanide complexes.",
        "abstract": "The reactivity of [Cp(2)Ln(mu-OH)(THF)]2 (Ln = Y (1), Er (2), Yb (3)) toward PhEtCCO, PhNCO, Cp3Ln, [Cp2Ln(mu-CH3)]2, and the LiCl adduct of Cp2Ln(n)Bu(THF)x was examined. In all cases, OH-centered reactivity is observed: complexes 1-3 react with PhEtCCO to form the O-H addition products [Cp2Ln(mu-eta1:eta2-O2CCHEtPh)]2 (Ln = Yb (5), Er (6), Y (7), respectively, for 1-3), whereas treatment of 1 with PhNCO affords the addition/CpH-elimination/rearrangement product [{Cp2Y(THF)}2(mu-eta2:eta2-O2CNPh)] (8), which contains an unusual PhNCO(2) dianionic ligand. Analogous compound [Cp2Ln(THF)]2(mu-eta2:eta2-O2CNPh) (Ln = Yb (9), Er (10)) and 8 can be obtained in a higher yield by treatment of [Cp2Ln(mu-OH)(THF)]2 with PhNCO followed by reaction with the corresponding Cp3Ln. However, attempts to prepare the corresponding heterobimetallic complex by reacting stoichiometric amounts of [Cp2Y(mu-OH)(THF)]2 with PhNCO followed by treating it with Cp3Yb are unsuccessful. Instead, only rearrangement products 8 and 9 are obtained. Furthermore, the reaction of 3 with [Cp2Yb(mu-CH3)]2 or Cp3Yb forms oxo-bridged compound [Cp2Yb(THF)]2(mu-O) (11), whereas the reaction of [Cp2ErCl]2 with Li(n)Bu followed by treatment with 2 affords unexpected mu-oxo lanthanocene cluster (Cp2Er)3(mu-OH)(mu3-O)(mu-Cl)Li(THF)4 (12). In contrast to 1 and 2, 3 shows a strong tendency to undergo the intermolecular elimination of CpH at room temperature, giving trinuclear species [Cp2Yb(mu-OH)]2[CpYb(THF)](mu3-O) (4). The single-crystal X-ray diffraction structures of 1, 2, and 4-12 are described. All the results offer an interesting contrast to transition- and main-metal hydroxide complexes.",
        "keywords": [],
        "authors": [
            {
                "name": "Chunmei Zhang",
                "org": ""
            },
            {
                "name": "Ruiting Liu",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Zhenxia Chen",
                "org": ""
            },
            {
                "name": "Xigeng Zhou",
                "org": ""
            }
        ],
        "venue": "Inorganic chemistry",
        "year": 2006
    },
    "9cstrxZx": {
        "id": "9cstrxZx",
        "title": "Reactivity of Organolanthanide Derivatives Containing the<i>o</i>-Aminothiophenolate Ligand toward Carbodiimide",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Liping Ma",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Zhengxing Zhang",
                "org": ""
            },
            {
                "name": "Ruifang Cai",
                "org": ""
            },
            {
                "name": "Zhenxia Chen",
                "org": ""
            },
            {
                "name": "Xigeng Zhou",
                "org": ""
            }
        ],
        "venue": "Organometallics",
        "year": 2006
    },
    "gauamziS": {
        "id": "gauamziS",
        "title": "Reactivity of organolanthanide derivatives containing the o-aminothiophenolate ligand toward carbodiimide",
        "abstract": "A series of lanthanocene derivatives containing the o-aminothiophenolate ligand have been synthesized, and their reactivities toward carbodiimide have been investigated. Reaction of N,N′-diisopropylcarbodiimide ( iPrN=C=NiPr) with [Cp2Yb(o-H2NC 6H4S)]2·2THF (Cp = C5H5) (1) yields a centrosymmetric dimer, [Cp(THF)Yb(μ-η3: η1-SC6H4N=C(NHiPr)N iPr)]2 (2), indicating that the adjacent NH2 group can add to the C=N double bonds of carbodiimide and one cyclopentadienyl group is eliminated. [Cp2Dy(o-H2-NC6H 4S)]2·3THF, obtained by protolysis of Cp 3Ln with o-aminothiophenol, reacts with 2 or 1 equiv of iPrN=C=NiPr in THF at room temperature to give the partial amino group addition product CpDy-(THF)[μ-η3: η1-SC6H4N=C(NHiPr)N iPr)](μ-η2:n1-SC6H 4NH2)DyCp2· THF (4). When Cp 3Dy reacts with o-aminothiophenol, and subsequently with iPrN=C=NiPr in toluene at room temperature, we isolated complex 4 and a small amount of [Cp2Dy(o-H2NC 6H4S)]2·2THF (5) and [Cp(THF)Dy(μ-η3:η1-SC6H 4N=C(NHiPr)NiPr)]2 (6). Treatment of 2 equiv of iPrN=C=NiPr with 3 in THF under reflux temperature also gave 4; the residual NH2 group cannot continuously add into the C=N bonds of other carbodiimide molecules. Reaction of Cp 3Er with 2 equiv of o-aminothiophenol and subsequently with 2 equiv of iPrN=C=NiPr in THF at room temperature yields the bis-addition product (C5H5)Er[SC6H 4-NC(NHiPr)2]2 (7). However, when Cp3Er reacts with 2 equiv of o-aminothiophenol, and subsequently with 1 equiv of iPrN=C=NiPr, the organic disulfide ( iPrHN)2CNC6H4SSC6H 4NCCNHiPr)2 (8) can be isolated. These results indicate that the addition of the adjacent amino group into the C=N double bonds of the carbodiimide molecule is strongly affected by the metal ion character and the steric hindrance of the ligands. All of the new compounds have been characterized by elemental analysis and spectroscopic properties. Their structures have also been determined through X-ray single-crystal diffraction analysis. © 2006 American Chemical Society.",
        "keywords": [],
        "authors": [
            {
                "name": "Liping Ma",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Zhengxing Zhang",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Ruifang Cai",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Zhenxia Chen",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Xigeng Zhou",
                "org": "Fudan University(Fudan University),Shanghai,China"
            }
        ],
        "venue": "Organometallics",
        "year": 2006
    },
    "l7rdn9iv": {
        "id": "l7rdn9iv",
        "title": "Multiple N-H bond activation: Synthesis and reactivity of functionalized primary amido ytterbium complexes",
        "abstract": "A series of new functionalized amido complexes of ytterbium, [Cp 2YbNHR]2 (R = 8-quinolyl(Qu) (1a), 2-pyridyl(Py) (1b), 2-aminophenyl (1c), 3-amino-2-pyridyl (1d), and Cp2Yb[NHC 6H4(CH2NH2-2)] (le), have been synthesized by metathesis of Cp2YbCl and the corresponding amido lithium salts. Their reactivity toward carbodiimides has been investigated, in which multiple N-H activation behavior for metal-bound neutral NH2 and anionic nitrogen-containing fragments, a property that is expressed without dissociation from the lanthanide center, is observed. These results provide an alternative mechanistic insight for the metal-mediated mono- and diguanylation of primary amines and elucidate factors that affect the chemo- and regioselectivities of the addition and protonation steps. Reaction of 1a with 2 equiv of RN=C=NR [R = cyclohexyl (Cy), isopropyl (lPr)] leads to the formal insertion of carbodiimide into the N-H bond of the Yb-bonded amido group to yield Cp2Yb[η1:η2-RNC(NHR)NQu] 2 [R = Cy (2a), iPr (2b)]. Interestingly, treatment of 1b with RN=C=NR affords the unexpected products (Cp2-Yb) 2μ-η2:η2-PyNC(NR)2](THF) [R = Cy (3a), iPr (3b)], representing the first example of dianionic guanidinate lanthanide complexes. The reaction of le with 2 equiv of RN=C=NR in THF at room temperature leads to the isolation of the single N-H addition products Cp2Yb[η1:η22-RNC(NHR)NC 6H4-NH2-2] [R = Cy (4a), iPr (4b)] in satisfied yields, while treatment of 1c with 4 equiv of RN=C=NR under the same conditions gives the double N-H addition products Cp2Yb[η 1:η22-RNC(NHR)NC6H4-{NC(NHR) 2-2}] [R = Cy (5a), iPr (5b)], via the intraligand proton transfer from chelating NH2 to the guanidinate group of 4 to give new amido intermediates, followed by a second RN=C=NR insertion into the N-H bond of the resulting amido groups. Complexes 5 can also be obtained by reacting 4 with 1 equiv of RN=C=NR. The double-addition product Cp2Yb[η 1:η2-CyNC(NHCy)NC5H3N{NC(NHCy) 23}] (6) could be obtained as red crystals from the 1:4 reaction between 1d and CyN=C=NCy in 63% yield. Interestingly, 6 can be converted into (Cp2Yb)2[η2:η3-(CyN) 2CNC5H3N{NC(NHCy)2-3}] (7) under reflux in THF and with liberation of a neutral diguanidine, C5H 3N(NC(NHCy)2)-2,3. A preference of the proton transfer to the second carbodiimide insertion into the N-H bond in the formation of 5 and 6 has been confirmed by the fact that treatment of weaker acidic le with an excess of carbodiimides in THF/ toluene, even with prolonged heating, provides only the monoaddition product Cp2Yb[η2:η1- CyNC(NHCy)NC6H4(CH2NH2-2)] [R = Cy (8a), iPr (8b)]. All complexes were characterized by elemental analysis and spectroscopic properties. The structures of all complexes except 2b, 3b, 4a, and 5b were also determined through X-ray crystal diffraction analysis. © 2007 American Chemical Society.",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Chengfu Pi",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Zhengxing Zhang",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Zhen Pang",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Jun Luo",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Zhenxia Chen",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Linhong Weng",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Xigeng Zhou",
                "org": "Fudan University(Fudan University),Shanghai,China"
            }
        ],
        "venue": "Organometallics",
        "year": 2007
    },
    "aSR6awJ2": {
        "id": "aSR6awJ2",
        "title": "Facile construction of novel organolanthanide square-planar macrocycles through addition of carbodiimide to an amino group.",
        "abstract": "The reactivity of lanthanocene derivatives containing the p-aminothiophenolate ligand towards carbodiimide was examined. Reaction of Cp2Ln(p-SC6H4NH2)(THF) with RN=C=NR in THF at room temperature gave four novel organolanthanide guanidinate complexes [Cp2Ln(p-SC6H4N(H)C(NHR)=NR)]4 (R = iPr, Ln = Yb (1a), Er (2a); R = Cy, Ln = Yb (2a), Er (2b)), formed by the addition of the C[double bond, length as m-dash]N double bonds of the carbodiimide molecule to the para-position amino group. Their unique square-planar macrocycle structures have been determined through X-ray single-crystal diffraction analysis. This result provides a potential method for the construction of organolanthanide macrocycles.",
        "keywords": [],
        "authors": [
            {
                "name": "Liping Ma",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Ruifang Cai",
                "org": ""
            },
            {
                "name": "Zhenxia Chen",
                "org": ""
            },
            {
                "name": "Xigeng Zhou",
                "org": ""
            }
        ],
        "venue": "Dalton transactions (Cambridge, England : 2003)",
        "year": 2007
    },
    "K0aF4b4t": {
        "id": "K0aF4b4t",
        "title": "Facile construction of lanthanide metallomacrocycles with the bridging imidazolate and triazolate ligands and their ring expansions.",
        "abstract": "Four novel tri- or tetranuclear organolanthanide metallomacrocycles [Cp2Ln(mu-Im)(THF)3 (Cp = C5H5, Ln = Yb (1), Er (2)], [Cp2Dy(mu-Im)]4(THF)]3 x 2THF (3), and [Cp'2Yb(mu-eta1:eta2-Tz)]4 x 2THF (Cp' = CH3C5H4) (4) have been synthesized through protolysis of Cp3Ln or Cp'3Yb with imidazole or triazole, indicating that both the bridge-ligand size and the lanthanide-ion radii can be applied in the modulation of the metallomacrocycles. Further investigations on the reactivity of complexes 1, 3, and 4 toward phenyl isocyanate reveal that PhNCO inserts readily into the simple bridge Ln-N bonds of 1 and 3 to yield the corresponding insertion products [Cp2Ln(mu-eta1:eta2-OC(Im)NPh)]3 (Ln = Yb (5), Dy (6)) but cannot insert into the Ln-N bond with a mu-eta1:eta2-bonding mode in 4. The novel bridge ligand [OC(Im)NPh] can expand the numbers of the ring members from 12 to 18 in 5 or 16 to 18 in 6. The number of metal atoms in the metallacycles with the ligand [OC(Im)NPh] is independent of the lanthanide-ion size; both trinuclear lanthanide macrocycles are observed in 5 and 6. All of these new complexes have been characterized by elemental analysis and spectroscopic properties, and their structures have also been determined through X-ray single-crystal diffraction analysis.",
        "keywords": [],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Ruifang Cai",
                "org": ""
            },
            {
                "name": "Zhenxia Chen",
                "org": ""
            },
            {
                "name": "Xigeng Zhou",
                "org": ""
            }
        ],
        "venue": "Inorganic chemistry",
        "year": 2007
    },
    "gxsdIt9L": {
        "id": "gxsdIt9L",
        "title": "Synthesis and structural characterizations of organolanthanide complexes with amino-tethered guanidinate ligand (C5H5)2Ln[H2N(CH2)3NC(NHiPr) NiPr)] (Ln=Yb, Y, Er, Dy)",
        "abstract": "Reaction of N , N ′-diisopropylcarbodiimide ( i PrN C N i Pr) with H 2 N(CH 2 ) 3 NH 2 and (C 5 H 5 ) 3 Ln, give (C 5 H 5 ) 2 Ln[H 2 N(CH 2 ) 3 N C(NH i Pr) N i Pr)] in high yields, indicating that the N–H bonds of one NH 2 group readily add to the C N double bonds of carbodiimide and one cyclopentadienyl group is eliminated to construct a novel amino-tethered guanidinate anionic ligand [H 2 N(CH 2 ) 3 N C(NH i Pr)N i Pr)] − . Keywords Addition Guanidinate Carbodiimide Diamine Organolanthanide Recently, nitrogen-based anionic ligands receive considerable attention from the desire to mimic the flexibility and remarkable reactivity of metallocene-based systems [1] . For example, the amidinate and guanidinate ligands have been well established as a versatile and flexible ligand system [2] . An important feature of these species is that their steric bulk and electronic properties can be modified by changing the organic substituents on the nitrogen atoms [3,4] . In metallocene chemistry, an important research field has been the development of cyclopentadienyl ligands to which other donor functionalities have been attached, which provided additional coordination opportunities and in some cases unique and high reactivity in olefin polymerizations [5] . However, little is known about the functional substituents of guanidinate ligands similar to the tethered cyclopentadienyl systems [6] . Organometallic guanidinates were usually synthesized by the metathesis reaction of the corresponding guanidinate salt with metal chlorides [7] . Insertion of carbodiimide into the metal-nitrogen bonds of organometallic amides as another choice strategy to synthesize organometallic guanidinates has also been developed in recent years [8] . However, there are some disadvantages about the two methods: the former has the difficulty of removing the byproducts of MCl (usually alkali metal chlorides) in the manipulations; the latter has low reactivity of the metal-ligand bonds toward carbodiimides. Recently, during the course of our investigations on the reaction of carbodiimides with organolanthanide o - or p -aminothiophenolates, we found that the ortho - or para -position amino groups can add to the C N bonds of carbodiimide molecules to construct the anionic guanidinate or neutral guanidino group [9] . The notable feature prompts us to explore the addition, and expand it as a new method for the construction of novel guanidinate ligand in organolanthanide chemistry. In this contribution, we reported a novel method for construction of the amino-tethered guanidinate anionic ligand in organolanthanide chemistry through addition of diamine with carbodiimide. Addition of one molar equivalent of diamine H 2 N(CH 2 ) 3 NH 2 and N , N ′-diisopropylcarbodiimide ( i PrN C N i Pr) to the THF solution of tri(cyclopentadienyl)lanthanide at room temperature gave the corresponding bis(cyclopentadienyl)lanthanide guanidinates Cp 2 Ln[H 2 N(CH 2 ) 3 N C (NH i Pr)N i Pr)] (Ln = Yb ( 1 ), Y ( 2 ), Er ( 3 ), Dy ( 4 )) in high yields, as shown in Scheme 1 [10] . This result indicates that the N–H bonds of one NH 2 group readily add to the C N double bonds of carbodiimide, and follow with the abstraction of one cyclopentadienyl group to construct the novel guanidinate monoanionic ligand [H 2 N(CH 2 ) 3 N C(NH i Pr)N i Pr)] − . Blank experimental results show that the addition of the diamine toward carbodiimide cannot occur under the same conditions without tris(cyclopentadienyl)lanthanide. It is unsuccessful to obtain the bis-addition products through the elevation temperature and/or increase the quantity of carbodiimide, only one amino group addition products 1 – 4 can be isolated. Furthermore, treatment of 2 equiv. of i PrN C N i Pr with 1 equiv. of H 2 N(CH 2 ) 3 NH 2 and 2 equiv of Cp 3 Yb under the same conditions also gave 1 and residual Cp 3 Yb, the residual NH 2 group cannot further add to the C N bonds of another carbodiimide molecules. Substituted guanidines are one kind of important organic molecules, and represent an essential functionality in many biologically and pharmaceutically relevant compounds [11] . The amines nucleophilic additions to carbodiimides catalyzed by organolanthanide alkyl complexes or Ln(OTf) 3 have been investigated recently [12] . However, these additions only occur under drastic conditions with high temperature (about 80 °C). Our results reveal the addition can take place under the more mild conditions, and provide a potential method for assembling the amino-tethered guanidines from amines and carbodiimide, and for the construction of some new support ligands in organolanthanide chemistry. Obviously, the present N–H bond activation pathway is different from the process of the previous reported N–H bond activation by other organometallic complexes. For example, N–H bond activation in transition-metal chemistry is by oxidative addition of metal ions [13] . N–H bond activation in organolanthanide-catalyzed hydroaminations generally proceed via protolysis of the amino group with the organolanthanide alkyl or amide complexes and subsequently C–C multiple bond insertion into the lanthanide–nitrogen bond [14] . In our study, the N–H bond activation should be the direct addition of the activated N–H bond to the C N bond of carbodiimide molecules, and is also different from the nucleophilic addition of secondary amine toward carbodiimide catalyzed by organolanthanide derivatives. The mechanism of the later is organic amine protolysis, carbodiimide insertion of the lanthanide–nitrogen bond, and ligand replacement [12] . All complexes 1 – 4 are air- and moisture-sensitive. They dissolve readily in THF and toluene, but are sparingly soluble in n -hexane. They have been characterized by elemental analysis and spectroscopic methods [15] . In the mass spectra, all complexes exhibit the molecule ion peak. Complexes 1 – 4 show a characteristic IR absorption band at about 1650 cm −1 attributable to the –N∴C∴N– stretching mode [16] . The solid structures of 1 and 2 were also identified by X-ray single-crystal diffraction analysis [17] . Complexes 1 and 2 crystallize from tetrahydrofuran at −20 °C in the monoclinic system, space group P 2 1 . The molecular structures of 1 and 2 are shown in Fig. 1 The structural analysis results show that 1 and 2 are isostructural. Both are solvent-free monomers with the lanthanide atom bonded to two η 5 -cyclopentadienyl rings, one chelating guanidinate ligand, and a coordinated amine group to form distorted bipyramid geometry. The coordination number of the central metal Ln 3+ is nine. The diffraction analysis results indicate that the amine molecules in 1 and 2 has combined with N , N ′-diisopropylcarbodiimide, forming a novel anionic guanidinate ligand [H 2 N(CH 2 ) 3 N C(NH i Pr)N i Pr)] − . One hydrogen atom of the adjacent amino group shifts to the uncoordinated nitrogen atom, is similar to that of the unsymmetrical guanidinate complexes Cp 2 Ln[RNC(NH i Pr)N i Pr] (R = t Bu, Ln = Yb, Er, Dy; R = Ph, Ln = Yb) [18] . The guanidinate ligand also exhibits delocalized bonding throughout the N 3 C guanidinate core. As expected, the coordinated guanidinate group forms essentially a planar four-membered ring with the lanthanide atom within experimental errors. The bond angles around C(14) are consistent with sp 2 hybridization. The planarity of YbN 2 C ring and nearly equivalent C14–N1 and C14–N3 (1.321(8) and 1.328(9) Å, respectively), Yb1–N1 and Yb1–N2 (2.3833(5) Å and 2.310(5) Å, respectively) bond lengths suggest the existence of a resonance stabilization in the YbN 2 C ring and no hydrogen atom at coordinated nitrogen atom. The distance between the central carbon and uncoordinated nitrogen (C14–N3 1.395(7) Å) is significantly shorter than the expected for C(sp 2 )–N(sp 3 ) single bonds (C–N av , 1.416) [19] , and indicate a stronger p–π conjugation between the lone-pair electron on non-coordinated nitrogen and the N–C–N unit. The Yb–C(Cp) distances range from 2.606(8) to 2.678(8) Å, and are in the normal ranges observed for the lanthanide metallocenes. The average Yb–C(Cp) distance of 2.664(8) Å is similar to those found in other Cp 2 Yb-containing compounds, such as [(C 5 H 5 ) 2 Yb(OCMe C CHMe)] 2 , 2.63(1) Å [20a] ; (C 5 H 5 ) 2 Yb(CH 3 )(THF), 2.60(2) Å [20b] . The structural parameters of 2 [17] are very similar to those for complex 1 , the Y–C(Cp) distances range from 2.629(6) to 2.697(7) Å. The average value of 2.664(7) Å is similar to those found in other trivalent lanthanide complexes, such as [(C 5 H 5 ) 2 Y(μ-CH 3 )] 2 , 2.66(2) Å [21] , and [(C 5 H 5 ) 2 Y( t BuN) 2 C( n Bu)], 2.644(6) Å [16b] . The Y–N distance of 2.338(4) Å and 2.405(5) Å are in the range expected for the Y–N bond interaction with partial single and a donor bond character [22] . The average Y–N distance of 2.371(5) Å is comparable to the corresponding distance in complex 1 , when the differences in the metal ionic radii are considered [23] . In summary, we have demonstrated that a novel method for construction of the amino-tethered guanidinate ligand in organolanthanide chemistry through addition of diamine with carbodiimide. In the presence of Cp 3 Ln, one of NH 2 group of diamine H 2 N(CH 2 ) 3 NH 2 readily add to the C N double bonds of carbodiimide and one cyclopentadienyl group is eliminated to construct a novel amino-tethered guanidinate anionic ligand [H 2 N(CH 2 ) 3 N C(NH i Pr)N i Pr)] − under more mild conditions. No further reaction was found even in the presence of a large excess of carbodiimide with a higher reaction temperature and a longer reaction time. This result provides a potential method for assembling the amino-tethered guanidines from amines and carbodiimide. Acknowledgements We thank the National Natural Science Foundation of China and the Research Funds of Young Teacher of Fudan University for financial support. Appendix A Supplementary material CCDC 641056 and 641055 contains the supplementary crystallographic data for ( 1 ) and ( 2 ). These data can be obtained free of charge via http://www.ccdc.cam.ac.uk/conts/retrieving.html , or from the Cambridge Crystallographic Data Centre, 12 Union Road, Cambridge CB2 1EZ, UK; fax: (+44) 1223-336-033; or e-mail: deposit@ccdc.cam.ac.uk . Supplementary data associated with this article can be found, in the online version, at doi:10.1016/j.inoche.2007.07.013 . Appendix A Supplementary data Supplementary data Experimental section. References [1] (a) Reviews: G.J.P. Britovsek V.C. Gibson D.F. Wass Angew. Chem., Int. Ed. 38 1999 429 (b) N. Marques A. Sella J. Takats Chem. Rev. 102 2002 2137 [2] (a) J. Barker M. Kilner Coord. Chem. Rev. 133 1994 219 (b) P.J. Bailey S. Pace Coord. Chem. Rev. 214 2001 91 [3] (a) S. Dagorne T.A. Guzei M.P. Coles R.F. Jordan J. Am. Chem. Soc. 122 2000 274 (b) R. Duchateau C.T. Wee J.H. Teuben Organometallics 15 1996 2291 (c) R. Duchateau C.T. Wee A. Meetsma J.H. Teuben J. Am. Chem. Soc. 115 1993 4931 (d) D.J. Dick R. Duchateau J.J.H. Edema S. Gambarotta Inorg. Chem. 32 1993 159 (e) F.A. Cotton T. Ren J. Am. Chem. Soc. 114 1992 2237 [4] (a) T.G. Ong G.P.A. Yap D.S. Richeson Organometallics 22 2003 387 (b) F.A. Cotton L.M. Daniels P.L. Huang C. Murillo Inorg. Chem. 41 2002 317 (c) P. Bazinet D. Wood G.P.A. Yap D.S. Richeson Inorg. Chem. 42 2003 6225 (d) A.P. Duncan S.M. Mullins J. Arnold R.G. Bergman Organometallics 20 2001 1808 (e) G.R. Giesbrecht G.D. Whitener J. Arnold Organometallics 19 2000 2809 [5] (a) W.J. Evans J.M. Perotti J.C. Brady J.W. Ziller J. Am. Chem. Soc. 125 2003 5204 (b) V.C. Gibson G.J.P. Britovsek D.F. Wass Angew. Chem., Int. Ed. 38 1999 428 (c) A.A. Trifonov E.N. Kirillov A. Fischer F.T. Edelmann M.N. Bochkarev Chem. Commun. 1999 2203 (d) H.H. Brintzinger N. Schneider M.E. Huttenloch U. Stehling R. Kirsten F. Schaper Organometallics 16 1997 3413 (e) J.E. Bercaw P.J. Shapiro D. Cotter W.P. Schaefer J.A. Labinger J. Am. Chem. Soc. 116 1994 4623 [6] (a) T.G. Ong G.P.A. Yap D.S. Richeson Organometallics 22 2003 387 (b) S. Bambirra M.J.R. Brandsma E.A.C. Brussee A. Meetsma B. Hessen J.H. Teuben Organometallics 19 2000 3197 [7] (a) Z. Lu G.P.A. Yap D.S. Richeson Organometallics 20 2001 706 (b) Y. Zhou G.P.A. Yap D.S. Richeson Organometallics 17 1998 4387 [8] (a) L.P. Ma J. Zhang R.F. Cai Z.X. Chen L.H. Weng X.G. Zhou J. Organomet. Chem. 690 2005 4926 (b) J. Zhang R.F. Cai L.H. Weng X.G. Zhou Organometallics 22 2003 5385 (c) J. Zhang R.F. Cai L.H. Weng X.G. Zhou J. Organomet. Chem. 672 2003 94 (d) G.R. Giesbrecht G.D. Whitener J. Arnold J. Chem. Soc. Dalton Trans. 2001 923 [9] (a) L.P. Ma J. Zhang Z.Z. Zhang R.F. Cai Z.X. Chen X.G. Zhou Organometallics 25 2006 4571 (b) J. Zhang L.P. Ma R.F. Cai L.H. Weng X.G. Zhou Organometallics 24 2005 738 (c) L.P. Ma J. Zhang R.F. Cai Z.X. Chen X.G. Zhou Dalton Trans. 2007 2718 [10] Synthesis : The mixture solution of N , N ’-diisopropylcarbodiimide (0.094 g, 1.26 mmol) and diamine H 2 N(CH 2 ) 3 NH 2 (0.159 g, 1.26 mmol) was added to a 30 mL THF solution of Cp 3 Yb (0.464 g, 1.26 mmol) at room temperature. The solution slowly turned from dark green to orange red over several minutes. After stirred for overnight, the reaction solution was concentrated to ca. 5 mL by reduced pressure. Orange crystals of 1 suitable for X-ray diffraction analysis were obtained after several days at −20 °C. Yield: 0.556 g (88 %). [11] (a) J.C. Manimala E.V. Anslyn Eur. J. Org. Chem. 2002 3909 (b) A. Mori B.D. Cohen A. Lowenthal Guanidines: Historical, Biological, Biochemical and Clinical Aspects of the Natually Occurring Guanidino Compounds 1985 Plenum Press New York [12] (a) W.X. Zhang M. Nishiura Z.M. Hou Synlett 2006 1213 (b) N. Yamamoto M. Isobe Chem. Lett. 1994 2299 [13] (a) A.L. Casalnuovo J.C. Calabrese D. Milstein J. Am. Chem. Soc. 110 1988 6738 (b) A.L. Casalnuovo J.C. Calabrese D. Milstein Inorg. Chem. 26 1988 971 [14] (a) S. Hong T.J. Marks Acc. Chem. Res. 33 2004 673 (b) G.A. Molander J.A.C. Romero Chem. Rev. 102 2002 2161 references therein [15] Selected spectroscopic data : for 1 : C, H, N analysis: calcd for C 20 H 33 N 4 Yb: C 47.80, H 6.62, N 11.15; found: C 47.74, H 6.60, N 11.21%; IR (Nujol): 3377 w, 3322 m, 3264 s, 1649 w,1592 m, 1552 s, 1402 w, 1342 s, 1310 s, 1267 s,1167 m, 1135 m, 1042 m, 1013 s, 940 m, 789 s, 751 s cm −1 ; MS (70 eV): m / z (%): 503 (34) [M]. for 2 : C, H, N analysis: calcd for C 20 H 33 N 4 Y: C 57.41, H 7.95, N 13.39; found: C 57.39, H 7.89, N 13.42%; IR (Nujol): 3377 w, 3322 m, 3266 s, 1648 w,1592 m, 1551 s, 1400 w, 1390 w, 1341 s, 1310 s, 1266 s,1168 m, 1133 m, 1039 m, 1015 s, 940 m, 787 s, 752 s cm −1 ; 1 H NMR (C 6 D 6 ): δ 6.29 (s, 10H, C 5 H 5 ), 3.58 (b, 2H, N H 2 ), 3.23 (s, H, N H i Pr), 2.69–2.83 (m, 4H, C H 2 CH 2 C H 2 ), 2.28–2.33 (m, 2H, CH 2 C H 2 CH 2 ), 1.19–1.20 (d, 6H, CH(C H 3 ) 2 ), 1.40–1.41 (d, 6H, CH(C H 3 ) 2 ); MS (70 eV): m / z (%): 418 (29) [M]. for 3 : C, H, N analysis : calcd for C 20 H 33 N 4 Er: C 48.36, H 6.70, N 11.28; found: C 48.33, H 6.70, N 11.35(%); IR (Nujol): 3376 w, 3322 m, 3265 s, 1648 w, 1590 m, 1551 s, 1401 w, 1341 s, 1309 s, 1268 s,1166 m, 1133 m, 1039 m, 1011 s, 940 m, 786 s, 750 s cm −1 ; MS (70 eV): m / z (%): 495 (16) [M]. for 4 : C, H, N analysis: calcd for C 20 H 33 N 4 Dy: C 48.82, H 6.76, N 11.39; found: C 48.77, H 6.72, N 11.49%; IR (Nujol): 3377 w, 3321 m, 3266 s, 1650 w, 1591 m, 1551 s, 1400 w, 1339 s, 1311 s, 1266 s,1167 m, 1134 m, 1041 m, 1009 s, 939 m, 786 s, 751 s cm −1 ; MS (70 eV): m / z (%): 493 (22) [M]. [16] (a) J.D. Wilkins J. Organomet. Chem. 80 1974 349 (b) J. Zhang R.Y. Ruan Z.H. Shao R.F. Cai L.H. Weng X.G. Zhou Organometallics 21 2002 1420 [17] Crystallographic data : for 1 : C 20 H 33 N 4 Yb, M w = 502.54, orthorhombic, space group P /2(1)2(1)2(1), a = 8.207(3) Å, b = 8.599(3) Å, c = 29.180(11) Å, V = 2059.3(14) Å 3 , Z = 4, D c = 1.621 g cm −3 , μ (Mo Kα) = 4.551 mm −1 , F (0 0 0) = 1004, 2 θ max = 54.00°. 10,160 reflections measured, of which 4421 were unique ( R int = 0.0506). Final R 1 = 0.0362 with wR 2 = 0.0825 for 4421 observed reflections with I > 2 σ ( I ). For 2 : C 20 H 33 N 4 Y, M w = 418.41, orthorhombic, space group P /2(1)2(1)2(1), a = 8.222(6) Å, b = 8.582(6) Å, c = 29.268(19) Å, V = 2065(2) Å 3 , Z = 4, D c = 1.346 g cm −3 , μ (Mo Kα) = 2.834 mm −1 , F (000) = 880, 2 θ max = 50.02°. 8665 reflections measured, of which 3634 were unique ( R int = 0.0755). Final R 1 = 0.0549 with wR 2 = 0.1003 for 3634 observed reflections with I > 2 σ ( I ). [18] J. Zhang R.F. Cai L.H. Weng X.G. Zhou Organometallics 23 2004 3303 [19] D.R. Lide Handbook of Chemistry and Physics 1996 CRC press Boca. Raton [20] (a) X.G. Zhou Z.Z. Wu Z.S. Jin J. Organomet. Chem. 431 1992 289 (b) W.J. Evans R. Dominguez T.B. Hanusa Organometallics 5 1986 263 [21] J. Holton M.F. Lappert D.R. Ballard R. Pearce J.L. Atwood W.E. Hunter J. Chem. Soc. Dalton trans. 1979 54 [22] W.J. Evans J.H. Meadows W.E. Hunter T.L. Atwood J. Am. Chem. Soc. 106 1984 1291 [23] R.D. Shannon Acta Crystal. A32 1976 751",
        "keywords": [],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Ruifang Cai",
                "org": "Department of Chemistry, Fudan University, Shanghai 200433, People’s Republic of China"
            },
            {
                "name": "Linhong Weng",
                "org": "Department of Chemistry, Fudan University, Shanghai 200433, People’s Republic of China"
            },
            {
                "name": "Xigeng Zhou",
                "org": ""
            }
        ],
        "venue": "Inorganic Chemistry Communications",
        "year": 2007
    },
    "qEWyPWER": {
        "id": "qEWyPWER",
        "title": "Synthesis and structural characterizations of organolanthanide complexes with amino-tethered guanidinate ligand (C 5 H 5 ) 2 Ln[H 2 N(CH 2 ) 3 N C(NH i Pr) N i Pr)] (Ln=Yb, Y, Er, Dy)",
        "abstract": "",
        "keywords": [
            "addition"
        ],
        "authors": [
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "ruifang cai",
                "org": ""
            },
            {
                "name": "linhong weng",
                "org": ""
            },
            {
                "name": "xigeng zhou",
                "org": ""
            }
        ],
        "venue": "Inorganic Chemistry Communications",
        "year": 2007
    },
    "noQcqdMh": {
        "id": "noQcqdMh",
        "title": "Synthesis and structural characterizations of organolanthanide complexes with amino-tethered guanidinate ligand (C5H5)2Ln[H2N(CH2)3N{double bond, long}C(NHiPr) NiPr)] (Ln = Yb, Y, Er, Dy)",
        "abstract": "Reaction of N,N′-diisopropylcarbodiimide (iPrN{double bond, long}C{double bond, long}NiPr) with H2N(CH2)3NH2 and (C5H5)3Ln, give (C5H5)2Ln[H2N(CH2)3N{double bond, long}C(NHiPr) NiPr)] in high yields, indicating that the N-H bonds of one NH2 group readily add to the C{double bond, long}N double bonds of carbodiimide and one cyclopentadienyl group is eliminated to construct a novel amino-tethered guanidinate anionic ligand [H2N(CH2)3N{double bond, long} C(NHiPr)NiPr)]-. © 2007.",
        "keywords": [
            "Addition",
            "Carbodiimide",
            "Diamine",
            "Guanidinate",
            "Organolanthanide"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Ruifang Cai",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Linhong Weng",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Xigeng Zhou",
                "org": "Fudan University(Fudan University),Shanghai,China"
            }
        ],
        "venue": "Inorganic Chemistry Communications",
        "year": 2007
    },
    "eqcLnsen": {
        "id": "eqcLnsen",
        "title": "Facile construction of a novel aminoquinazolinate anionic ligand through organolanthanide-mediated intermolecular nucleophilic addition/cyclization of anthranilonitrile.",
        "abstract": "Compounds Cp 2Ln[kappa (3)-(4-NH(C 8N 2H 4)(2-NH 2C 6H 4)] [Cp = C 5H 5; Ln = Er ( 1), Y ( 2)] were synthesized by the reaction of Cp 2LnN (i) Pr 2(THF) with anthranilonitrile, indicating a novel organolanthanide-mediated intermolecular nucleophilic addition/cyclization of anthranilonitrile. To trap the intermediate I, a probe reaction of Cp 2ErN (i) Pr 2(THF) with anthranilonitrile and carbodiimide has also been investigated.",
        "keywords": [],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Yanan Han",
                "org": ""
            },
            {
                "name": "Fuyan Han",
                "org": ""
            },
            {
                "name": "Zhenxia Chen",
                "org": ""
            },
            {
                "name": "Linhong Weng",
                "org": ""
            },
            {
                "name": "Xigeng Zhou",
                "org": ""
            }
        ],
        "venue": "Inorganic chemistry",
        "year": 2008
    },
    "vWxPSZ0D": {
        "id": "vWxPSZ0D",
        "title": "Synthesis of mixed Cp/tpMe2 lanthanide complexes from lanthanocene precursors and their structures and reactivities",
        "abstract": "Reaction of Cp2LnCI with 1 equiv of KTpMe2 in toluene gives the mixed TpMe2/Cp lanthanide complexes Cp 2Ln(TpMe2) (Ln = Yb (1a), Er (1b), Dy (1c)), while unexpected complexes CpLn(TpMe2)CI(THF) (Ln = Yb (2a), Er (2b-THF), Dy (2c), Y (2d)) are obtained when the reactions are carried out in THF. Complex 2b can also be formed by the reaction of CpErCI2(THF)3 with 1 equiv of KTpMe2 in THF. Moreover, complex 1a can also be obtained from the reaction of Cp3Yb and KTpMe2. The results not only represent an efficient and versatile method for the synthesis of mixed Cp/TpMe2 lanthanide complexes but also provide new insight into the reactivity of Cp2LnCI. Furthermore, the reactivities of complexes 1a-c toward proton-donating reagents are examined. It has been found that 1b reacts with benzotriazole (C6H4NHN2) in THF to yield a lanthanide metallomacroeyelic complex [(TpMe2)CpEr(μ- N3C6H4)]3 (3), while the reaction of 1a with 1 equiv of 2-aminopyridine in THF gives an unexpected oxide complex [(TpMe2)Yb(2-HNC5H4N)]2(μ-O) (4). Presumably, the oxide ligand of compound 4 results from adventitious water. In addition, treatment of 1c with 2 equiv of 3,5-dimethylpyrazole yields a completely Cp-abstracted product (TpMe2)Dy(PzMe2) 2(THF) (5), which can also be directly obtained from a three-component reaction of Cp2DyCI, KTpMe2, and 3,5-dimethylpyrazole in THF. These results further indicate that the new mixed TpMe2/Cp lanthanide complexes are practical and versatile precursors for the synthesis of poly(pyrazolyl)borate lanthanide derivatives. All new compounds have been characterized by elemental analysis and spectroscopic methods. The structures of complexes 1a,b and 2-5 have also been determined through single-crystal X-ray diffraction analysis. © 2009 American Chemical Society.",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Fuyan Han",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Yanan Han",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Zhengxing Zhang",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Zhenxia Chen",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Linhong Weng",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Xigeng Zhou",
                "org": "Fudan University(Fudan University),Shanghai,China"
            }
        ],
        "venue": "Inorganic Chemistry",
        "year": 2009
    },
    "klRNPfOi": {
        "id": "klRNPfOi",
        "title": "Investigations on organolanthanide derivatives with the hydrazonido ( -NHN=CPh2) ligand: synthesis, crystal structure, and reactivity",
        "abstract": "Two organolanthanide complexes with the benzophenone hydrazonido(l-) ligand, [Cp2Yb(MNHN=CPh2)]2 (1) and Cp 2Er[η2-NHN=CPh2](THF) (2), were synthesized by abstraction of cyclopentadienyl from CpaLn with 1 equiv of benzophenone hydrazone in THF. Reaction of 1 and 2 with phenyl isocyanate gives Ln-N bond insertion with the 1,3-H migration products Cp2Ln[η-OC (NHPh)NN=CPh2)(HMPA) (Ln = Yb (3), Er (4)). However, 1 and 2 react with PhNCS to give Ln-N bond insertion without the 1,3-H migration products Cp2Ln[η2-SC(NHN=CPh2)NPh)(HMPA) (Ln = Yb (5), Er (6)) under the same conditions. PhCN inserts into the Er-N bond of 2 with 1,3-hydrogen migration to form the organolanthanide heterometallacycles Cp2ErV-NHC(Ph)NN=CPh2] (7). However, 'BuNC does not insert into the Er-N bond of 2 under the same conditions, and treatment of 2 with 'BuNC leads to the isolation of the solvent-free dimer [Cp2Er(μ- η1η 2-NHN=CPh2)]2 (2'). All new compounds have been characterized through X-ray single-crystai diffraction analysis. © 2009 American Chemical Society.",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Yanan Han",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Fuyan Han",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Zhengxing Zhang",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Linhong Weng",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Xigeng Zhou",
                "org": "Fudan University(Fudan University),Shanghai,China"
            }
        ],
        "venue": "Organometallics",
        "year": 2009
    },
    "3YzMXd5p": {
        "id": "3YzMXd5p",
        "title": "Synthesis and structures of titanium and yttrium complexes with N,N'-tetramethylguanidinate ligands: different reactivity of the M-N bonds toward phenyl isocyanate.",
        "abstract": "A salt elimination reaction of bis(cyclopentadienyl)titanium dichloride (C(5)H(5))(2)TiCl(2) with one equiv. of N,N'-tetramethylguanidinate lithium [LiN[double bond, length as m-dash]C(NMe(2))(2)] proceeded in THF at room temperature to yield a bis(cyclopentadienyl)titanium mono-guanidinate chloride (C(5)H(5))(2)TiCl(N[double bond, length as m-dash]C(NMe(2))(2)) (). However, treatment of two equiv. of LiN[double bond, length as m-dash]C(NMe(2))(2) with (C(5)H(5))(2)TiCl(2) under the same conditions resulted in the elimination of one cyclopentadienyl ring to form an unexpected mono(cyclopentadienyl)titanium bis(guanidinate) chloride (C(5)H(5))TiCl[N[double bond, length as m-dash]C(NMe(2))(2)](2) (), in which only one Ti-Cl bond is broken, with the other Ti-Cl bond retained. Reaction of [(C(5)H(5))(2)YCl](2) with LiN[double bond, length as m-dash]C(NMe(2))(2) gave the corresponding product {(C(5)H(5))(2)Y[mu-eta(1):eta(2)-N[double bond, length as m-dash]C(NMe(2))(2)]}(2) (). On further investigations on the reactivity of toward phenyl isocyanate, we found phenyl isocyanate only inserts into the Y-N(mu-Gua) bonds of to yield [(C(5)H(5))(2)Y(mu-eta(1):eta(2)-OC(N[double bond, length as m-dash]C(NMe(2))(2))NPh)](2) (). Complexes were characterized by elemental analysis and spectroscopic properties and their solid-state structures were determined by X-ray single-crystal diffraction.",
        "keywords": [
            "titanium"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Fuyan Han",
                "org": ""
            },
            {
                "name": "Yanan Han",
                "org": ""
            },
            {
                "name": "Zhenxia Chen",
                "org": ""
            },
            {
                "name": "Xigeng Zhou",
                "org": ""
            }
        ],
        "venue": "Dalton transactions (Cambridge, England : 2003)",
        "year": 2009
    },
    "jrcWbbA7": {
        "id": "jrcWbbA7",
        "title": "Synthesis of mixed Cp/Tp(Me2) lanthanide complexes from lanthanocene precursors and their structures and reactivities.",
        "abstract": "Reaction of Cp(2)LnCl with 1 equiv of KTp(Me2) in toluene gives the mixed Tp(Me2)/Cp lanthanide complexes Cp(2)Ln(Tp(Me2)) (Ln = Yb (1a), Er (1b), Dy (1c)), while unexpected complexes CpLn(Tp(Me2))Cl(THF) (Ln = Yb (2a), Er (2b.THF), Dy (2c), Y (2d)) are obtained when the reactions are carried out in THF. Complex 2b can also be formed by the reaction of CpErCl(2)(THF)(3) with 1 equiv of KTp(Me2) in THF. Moreover, complex 1a can also be obtained from the reaction of Cp(3)Yb and KTp(Me2). The results not only represent an efficient and versatile method for the synthesis of mixed Cp/Tp(Me2) lanthanide complexes but also provide new insight into the reactivity of Cp(2)LnCl. Furthermore, the reactivities of complexes 1a-c toward proton-donating reagents are examined. It has been found that 1b reacts with benzotriazole (C(6)H(4)NHN(2)) in THF to yield a lanthanide metallomacrocyclic complex [(Tp(Me2))CpEr(mu-N(3)C(6)H(4))](3) (3), while the reaction of 1a with 1 equiv of 2-aminopyridine in THF gives an unexpected oxide complex [(Tp(Me2))Yb(2-HNC(5)H(4)N)](2)(mu-O) (4). Presumably, the oxide ligand of compound 4 results from adventitious water. In addition, treatment of 1c with 2 equiv of 3,5-dimethylpyrazole yields a completely Cp-abstracted product (Tp(Me2))Dy(Pz(Me2))(2)(THF) (5), which can also be directly obtained from a three-component reaction of Cp(2)DyCl, KTp(Me2), and 3,5-dimethylpyrazole in THF. These results further indicate that the new mixed Tp(Me2)/Cp lanthanide complexes are practical and versatile precursors for the synthesis of poly(pyrazolyl)borate lanthanide derivatives. All new compounds have been characterized by elemental analysis and spectroscopic methods. The structures of complexes 1a,b and 2-5 have also been determined through single-crystal X-ray diffraction analysis.",
        "keywords": [
            "database",
            "chemical",
            "material",
            "chemical engineering",
            "chemistry"
        ],
        "authors": [
            {
                "name": "Fuyan Han",
                "org": "Department of Chemistry, Fudan University, Shanghai 200433, People's Republic of China."
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Yanan Han",
                "org": ""
            },
            {
                "name": "Zhengxing Zhang",
                "org": ""
            },
            {
                "name": "Zhenxia Chen",
                "org": ""
            },
            {
                "name": "Linhong Weng",
                "org": ""
            },
            {
                "name": "Xigeng Zhou",
                "org": ""
            }
        ],
        "venue": "Inorganic chemistry",
        "year": 2009
    },
    "MepM7WjA": {
        "id": "MepM7WjA",
        "title": "Investigations on Organolanthanide Derivatives with the Hydrazonido (<sup>−</sup>NHN═CPh<sub>2</sub>) Ligand: Synthesis, Crystal Structure, and Reactivity",
        "abstract": "",
        "keywords": [
            "crystal structure"
        ],
        "authors": [
            {
                "name": "Yanan Han",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Fuyan Han",
                "org": ""
            },
            {
                "name": "Zhengxing Zhang",
                "org": ""
            },
            {
                "name": "Linhong Weng",
                "org": ""
            },
            {
                "name": "Xigeng Zhou",
                "org": ""
            }
        ],
        "venue": "Organometallics",
        "year": 2009
    },
    "YcdNsw87": {
        "id": "YcdNsw87",
        "title": "Facile construction of the guanidine substituent or guanidinate anionic ligand through addition of the adjacent amino group to carbodiimide.",
        "abstract": "The reaction of N,N'-dicyclohexylcarbodiimide (DCCI) with [Cp(2)Yb(o-H(2)NC(6)H(4)S)](2) (Cp = C(5)H(5)) () forms the monomer product Cp(2)Yb[SC(6)H(4)N[double bond, length as m-dash]C(NHCy)(2)] (), indicating that the adjacent NH(2) group can add to the C[double bond, length as m-dash]N double bonds of carbodiimide to construct a neutral guanidine group. When DCCI reacts with [Cp(2)Y(o-H(2)NC(6)H(4)S)](2).2THF (), a dimer product [CpY(mu-eta(2):eta(1)-SC(6)H(4)N[double bond, length as m-dash]C(NHCy)NCy)(THF)](2) () was isolated, through the amino group addition and cyclopentadienyl elimination. Interestingly, on treatment of with one or two equivalent of (i)PrN[double bond, length as m-dash]C[double bond, length as m-dash]N(i)Pr at the same conditions gave an amino group partial addition product CpY(THF)[mu-eta(2):eta(1)-SC(6)H(4)N[double bond, length as m-dash]C(NH(i)Pr)N(i)Pr)](mu-eta(2):eta(1)-SC(6)H(4)NH(2))YCp(2).THF (), where only one NH(2) group can add to the C[double bond, length as m-dash]N double bonds of carbodiimide molecule, another one is remained. However, when we extended this reaction to the gadolinium complex, a novel co-crystalline compound {Cp(2)Gd[SC(6)H(4)N[double bond, length as m-dash]C(NHCy)(2)]}.{CpGd(THF)[mu-eta(2):eta(1)-SC(6)H(4)N[double bond, length as m-dash]C(NHCy)NCy)][mu-eta(2):eta(1)-SC(6)H(4)NH(2)]GdCp(2).THF} () was obtained from the reaction of [Cp(2)Gd(o-H(2)NC(6)H(4)S)](2) () with DCCI. In order to investigate the sequence of addition and the elimination of the cyclopentadienyl group, a deprotonation reaction of the addition product has also been studied. Reaction of CpYb[SC(6)H(4)NC(NH(i)Pr)(2)](2)(THF) (), formed by reaction of Cp(3)Yb with two equivalent of o-aminothiophenol, and subsequently with 2 equiv. of (i)PrN[double bond, length as m-dash]C[double bond, length as m-dash]N(i)Pr, with one equiv. of Cp(3)Yb gave a cyclopentadienyl elimination product [CpYb(mu-eta(2):eta(1)-SC(6)H(4)N[double bond, length as m-dash]C(NH(i)Pr)N(i)Pr)(THF)](2) (). This result reveals that addition of the NH(2) group to carbodiimide is prior to the elimination of cyclopentadienyl group. All of new compounds have been characterized by elemental analysis and spectroscopic properties. The solid-state structures of complexes , and were determined by single-crystal X-ray diffraction.",
        "keywords": [],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Liping Ma",
                "org": ""
            },
            {
                "name": "Yanan Han",
                "org": ""
            },
            {
                "name": "Fuyan Han Zhengxing Zhang",
                "org": ""
            },
            {
                "name": "Ruifang Cai",
                "org": ""
            },
            {
                "name": "Zhenxia Chen",
                "org": ""
            },
            {
                "name": "Xigeng Zhou",
                "org": ""
            }
        ],
        "venue": "Dalton transactions (Cambridge, England : 2003)",
        "year": 2009
    },
    "4pbF8btr": {
        "id": "4pbF8btr",
        "title": "ChemInform Abstract: Novel Cp2LnX-Mediated Coupling-Cyclization of Propargyl Bromide: A New Construction of the Benzene Ring Skeleton.",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Ruyi Ruan",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Xigeng Zhou",
                "org": ""
            },
            {
                "name": "Ruifang Cai",
                "org": ""
            }
        ],
        "venue": "Cheminform",
        "year": 2010
    },
    "iQ3QXQeW": {
        "id": "iQ3QXQeW",
        "title": "γ-Deprotonation of Anionic Bis(trimethylsilyl)amidolanthanide Complexes with a Countered [(Tp<sup>Me2</sup>)<sub>2</sub>Ln]<sup>+</sup>Cation",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Fuyan Han",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Weiyin Yi",
                "org": ""
            },
            {
                "name": "Zhengxing Zhang",
                "org": ""
            },
            {
                "name": "Jingyi Yu",
                "org": ""
            },
            {
                "name": "Linhong Weng",
                "org": ""
            },
            {
                "name": "Xigeng Zhou",
                "org": ""
            }
        ],
        "venue": "Inorganic Chemistry",
        "year": 2010
    },
    "jPuAcULr": {
        "id": "jPuAcULr",
        "title": "Recent advances in reaction of organolanthanides containing the N-H bonds with unsaturated organic small molecules",
        "abstract": "This article is intended to provide an overview on recent progress in the reaction chemistry of organolanthanide complexes with the nitrogen-hydrogen bonds toward a series of unsaturated organic small molecules. The synthesis, stoichiometric and catalytic reactions of these complexes are described. © 2010 Académie des sciences. Published by Elsevier Masson SAS. All rights reserved.",
        "keywords": [
            "Metallocenes Rare earths Nitrogen Insertion N ligands"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Xigeng Zhou",
                "org": "Fudan University(Fudan University),Shanghai,China"
            }
        ],
        "venue": "Comptes rendus - Chimie",
        "year": 2010
    },
    "ScNxAJDY": {
        "id": "ScNxAJDY",
        "title": "γ-Deprotonation of anionic bis(trimethylsilyl)amidolanthanide complexes with a countered [(TpMe2)2Ln]+ Cation",
        "abstract": "TpMe2LnCl2 (1) reacts with 2 equiv of KN(SiMe3)2 in tetrahydroturan at room temperature to yield the ligand redistribution/y- deprotonation products [(TpMe2)2Ln]+[((Me 3Si)2N)2Ln(CH2)SiMe 2N(SiMe3)]- [Ln = Er (2), Y (3)]. Complex 2 can also be obtained by reacting [(Me3Si)2N]2ErCl with KTpMe2. However, 1 reacts with 1.5 and 1 equiv of KN(SiMe 3)2 to yield [(TpMe2)2Er] +[((Me3Si)2N)3ErCl (4) and [(Tp Me2)2Er]+{[(Me3Si) 2N)TpMe2ErCl]2(μ-Cl)2K} (5), respectively. Furthermore, it is found that 2 reacts with 2 equiv of CyN=C=NCy (Cy = cyclohexyl) to give the tandem HN(SiMe3)2 elimination and Ln-C insertion product (TpMe2)Er[(CyN) 2CCH2SiMe2N(SiMe3)] (6) in 71% isolated yield. The results reveal that the γ-deprotonation degree of advancement increases with an increase of the steric hindrance around the central metal ion. All new complexes have been characterized by elemental analysis and spectroscopic properties, and their solid-state structures have also been determined through single-crystal X-ray diffraction analysis. © 2010 American Chemical Society.",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Fuyan Han",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Weiyin Yi",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Zhengxing Zhang",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Jingyi Yu",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Linhong Weng",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Xigeng Zhou",
                "org": "Fudan University(Fudan University),Shanghai,China"
            }
        ],
        "venue": "Inorganic Chemistry",
        "year": 2010
    },
    "aMDbK9rU": {
        "id": "aMDbK9rU",
        "title": "Insertion of ketenimines into the ln-c σ-bond of organolanthanides: A new strategy for synthesis of lanthanide 1-azaallyl complexes",
        "abstract": "Treatment of [Cp2Ln(μ-Me)]2 and Cp2LnPh with PhRC - C - NtBu gives the insertion products Cp 2Ln[tBuNC(R-)CRPh] (R = Ph, R- = Me, Ln = Y (1-Y), Er (1-Er), Yb (1-Yb); R = Ph, R- = Ph, Ln = Y (2-Y), Er (2-Er), Yb (2-Yb); R = H, R-= Me, Ln = Y (3-Y), Er (3-Er), Yb (3-Yb); R = H, R- = Ph, Ln = Y (4-Y), Er (4-Er), Yb (4-Yb)), which represents the first example of ketenimine insertion into a lanthanide-carbon bond and provides an efficient method for the synthesis of organometallic complexes with the 1-azaallyl ligands. It is found that an excess of ketenimine does not affect the nature of the final complexes, with only a monoinsertion product being observed. All these complexes are characterized by elemental analysis and spectroscopic properties. The structures of these complexes have also been determined through X-ray single-crystal diffraction analysis, revealing a novel bonding mode of aryl-substituted azaallyls to a metal. © 2010 American Chemical Society.",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Zhengxing Zhang",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Xiuli Bu",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Ruiting Liu",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Xigeng Zhou",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Linhong Weng",
                "org": "Fudan University(Fudan University),Shanghai,China"
            }
        ],
        "venue": "Organometallics",
        "year": 2010
    },
    "mYh1ztcr": {
        "id": "mYh1ztcr",
        "title": "Promoting Security in Electronic Marketplaces through the Modeling of Trust",
        "abstract": "In this paper, we introduce two methods that serve to of- fer increased security for buying and selling agents in electronic mar- ketplaces. The flrst method operates in an environment where buying agents may consult other buying agents to acquire ratings of the trust- worthiness of sellers. Seller security is promoted by ofiering rewards to buyers who have been considered trustworthy by large numbers of other buyers in the marketplace. We include experimental evidence to demon- strate that honest buyers will gain greater proflt. The second method is aimed at buyers who are independently selecting sellers with whom to do business. Sellers can only ofier goods for sale if they have established su-cient trust units, called trunits. They lose these units when buyers are unsatisfled with the sales made. We demonstrate how this system promotes buyer security in the marketplace, as sellers who do not cheat will derive greater proflt. We conclude with some general remarks about the importance of modeling trust in electronic markets, not only to fa- cilitate the selection of trustworthy partners but also to provide a level of security to buying and selling agents.",
        "keywords": [],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Reid Kerr",
                "org": ""
            },
            {
                "name": "Robin Cohen",
                "org": ""
            },
            {
                "name": "J. Zhang",
                "org": ""
            },
            {
                "name": "R. Kerr",
                "org": ""
            },
            {
                "name": "R. Cohen",
                "org": ""
            }
        ],
        "venue": "",
        "year": 0
    },
    "zk3w4b0I": {
        "id": "zk3w4b0I",
        "title": "Towards More Effective E-Marketplaces: A Novel Incentive Mechanism",
        "abstract": "In the context of electronic commerce, the problem of unfair ratings arises when modeling the trustworthiness of a selling agent relies (partially) on propagation of ratings provided by buying agents that have personal experience with the seller. Extreme diversity of open and dynamic electronic market- places causes difficulties in handling unfair ratings in trust management systems. To ease this problem, we propose a novel incentive mechanism for eliciting fair ratings of sellers from buyers. In our mechanism, buyers model other buyers, using an approach that combines both private and public rep- utation values. In addition, however, sellers model the repu- tation of buyers. Reputable buyers provide fair ratings of sell- ers, and are likely considered trustworthy by many other buy- ers. In marketplaces operating with our mechanism, sellers will offer more attractive products to satisfy reputable buyers, in order to build their reputation. In consequence, our mech- anism creates incentives for buyers to provide fair ratings of sellers, leading to more effective e-marketplaces where hon- est buyers and sellers can gain more profit.",
        "keywords": [],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Robin Cohen",
                "org": ""
            }
        ],
        "venue": "",
        "year": 0
    },
    "9qqePvRH": {
        "id": "9qqePvRH",
        "title": "A Comprehensive Approach for Sharing Semantic Web Trust Ratings",
        "abstract": "",
        "keywords": [
            "semantic web",
            "web of trust"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Robin Cohen",
                "org": ""
            }
        ],
        "venue": "Computational Intelligence",
        "year": 2007
    },
    "iiqjziwo": {
        "id": "iiqjziwo",
        "title": "Engendering Trust in Buying and Selling Agents by Discouraging the Reporting of Unfair Ratings.",
        "abstract": "",
        "keywords": [
            "satisfiability",
            "profitability"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Robin Cohen",
                "org": ""
            }
        ],
        "venue": "AAAI Spring Symposium: Interaction Challenges for Intelligent Assistants",
        "year": 2007
    },
    "zelkOGv4": {
        "id": "zelkOGv4",
        "title": "A Detailed Comparison of Probabilistic Approaches for Coping with Unfair Ratings in Trust and Reputation Systems",
        "abstract": "The unfair rating problem exists when a buying agent models the trustworthiness of selling agents by also relying on ratings of the sellers from other buyers. Different probabilistic approaches have been proposed to cope with this issue. In this paper, we first summarize these approaches and provide a detailed categorization of them. This includes our own \"personalized\" approach for addressing this problem. Based on the implication of such analysis, we then focus on experimental comparison of our approach with two key models in a framework that simulates a dynamic electronic marketplace environment. We specifically examine different scenarios, including ones where the majority of buyers are dishonest, buyers lack personal experience with sellers, sellers may vary their behavior, and buyers may provide a large number of ratings. Our study provides the basis for deciding which approach is most appropriate to employ, in which scenario.",
        "keywords": [
            "detailed categorization",
            "probabilistic approaches",
            "different scenario",
            "trust systems",
            "buying agent model",
            "personal experience",
            "reputation systems",
            "selling agents",
            "detailed comparison",
            "large number",
            "unfair rating problem",
            "experimental comparison",
            "unfair ratings",
            "dynamic electronic marketplace environment",
            "electronic commerce",
            "buying agent",
            "different probabilistic approach",
            "key model",
            "bayesian methods",
            "probability density function",
            "probabilistic logic",
            "prediction algorithms",
            "servers"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Murat Sensoy",
                "org": ""
            },
            {
                "name": "Robin Cohen",
                "org": ""
            }
        ],
        "venue": "PST",
        "year": 2008
    },
    "73XVHEp6": {
        "id": "73XVHEp6",
        "title": "POYRAZ: Context-Aware Service Selection under Deception",
        "abstract": "",
        "keywords": [
            "semantic web",
            "electronic commerce"
        ],
        "authors": [
            {
                "name": "Murat Sensoy",
                "org": "bogazici university"
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Pinar Yolum",
                "org": "bogazici university"
            },
            {
                "name": "Robin Cohen",
                "org": ""
            }
        ],
        "venue": "Computational Intelligence",
        "year": 2009
    },
    "ShCuXtmR": {
        "id": "ShCuXtmR",
        "title": "Mechanism Design on Coursework Grading to Create Incentives for Student Learning",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "julita vassileva",
                "org": ""
            },
            {
                "name": "ralph deters",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2010
    },
    "n3rAi1YB": {
        "id": "n3rAi1YB",
        "title": "A Framework of User-Driven Data Analytics in the Cloud for Course Management",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "william chandra tjhi",
                "org": ""
            },
            {
                "name": "bu sung lee",
                "org": ""
            },
            {
                "name": "kee khoon lee",
                "org": ""
            },
            {
                "name": "julita vassileva",
                "org": ""
            },
            {
                "name": "chee kit looi",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2010
    },
    "e5BOEnZO": {
        "id": "e5BOEnZO",
        "title": "Secure and Efficient Trust Opinion Aggregation for Vehicular Ad-Hoc Networks",
        "abstract": "",
        "keywords": [
            "digital signatures",
            "comparative analysis",
            "silicon",
            "quality of information",
            "ad hoc networks",
            "vehicular ad hoc network",
            "public key"
        ],
        "authors": [
            {
                "name": "Chen Chen",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Robin Cohen",
                "org": ""
            },
            {
                "name": "Pin-Han Ho",
                "org": ""
            }
        ],
        "venue": "VTC Fall",
        "year": 2010
    },
    "OtxDDbj5": {
        "id": "OtxDDbj5",
        "title": "A Trust Modeling Framework for Message Propagation and Evaluation in VANETs",
        "abstract": "In this paper, we present a trust-based message propagation and evaluation framework in vehicular ad-hoc networks where peers share information regarding road condition or safety and others provide opinions about whether the information can be trusted. More specifically, our trust-based message propagation model collects and propagates peers' opinions in an efficient, secure and scalable way by dynamically controlling information dissemination. The trust-based message evaluation model allows peers to evaluate the information in a distributed and collaborative fashion by taking into account others' opinions. Experimental results demonstrate that our proposed framework promotes network scalability and system effectiveness in information evaluation under the pervasive presence of false information, which are the two essentially important factors for the popularization of vehicular networks.",
        "keywords": [
            "ad hoc networks",
            "mobile radio",
            "road safety",
            "telecommunication security",
            "information dissemination",
            "road condition",
            "trust modeling",
            "trust-based message propagation model",
            "vehicular ad hoc networks",
            "computational modeling",
            "lead",
            "scalability",
            "vehicular ad hoc network"
        ],
        "authors": [
            {
                "name": "Chen Chen",
                "org": "Sch. of Comput. Eng., Nanyang Technol. Univ., Singapore, Singapore|c|"
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Cohen, R.",
                "org": ""
            },
            {
                "name": "Pin-Han Ho",
                "org": ""
            }
        ],
        "venue": "Information Technology Convergence and Services",
        "year": 2010
    },
    "uOqbLZGw": {
        "id": "uOqbLZGw",
        "title": "Leveraging a Social Network of Trust for Promoting Honesty in E-Marketplaces",
        "abstract": "\n In this paper, we examine a trust-based framework for promoting honesty in e-marketplaces that relies on buyers forming social\n networks to share reputation ratings of sellers and sellers rewarding the buyers that are most respected within their social\n networks. We explore how sellers reason about expected future profit when offering particular rewards for buyers. We theoretically\n prove that in a marketplace operating with our mechanism: i) buyers will be better off honestly reporting seller ratings and\n ii) sellers are better off being honest, to earn better profit. Experiments confirm the robustness of the approach, in dynamically\n changing environments. With rational agents preferring to be honest, the buyer and seller strategies as specified constitute\n an effective approach for the design of e-marketplaces.\n \n ",
        "keywords": [
            "rational agent",
            "social network",
            "profitability"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Nanyang Technological University School of Computer Engineering Singapore"
            },
            {
                "name": "Robin Cohen",
                "org": "University of Waterloo School of Computer Science Canada"
            },
            {
                "name": "Kate Larson",
                "org": "University of Waterloo School of Computer Science Canada"
            }
        ],
        "venue": "IFIPTM",
        "year": 2010
    },
    "oVgv7iVQ": {
        "id": "oVgv7iVQ",
        "title": "Intelligent Agents in Mobile Vehicular Ad-Hoc Networks: Leveraging Trust Modeling Based on Direct Experience with Incentives for Honesty",
        "abstract": "In this paper we introduce a multi-faceted trust model of use for the application of ad-hoc vehicular networks (VANETs) – scenarios where agents representing drivers exchange information with other drivers regarding road and traffic conditions. We argue that there is a need to model trust in various dimensions and that combining these elements effectively can assist agents in making transportation decisions. We then introduce two new elements to our proposed model: i) distinguishing direct and indirect reports that are shared ii) employing a penalty for misleading reports, to promote honesty. We demonstrate how these two elements together serve to increase the value of the trust model, through a series of experiments of simulated traffic. In brief, we present a framework to facilitate the effective sharing of information in VANET environments between agents representing the vehicles.",
        "keywords": [
            "ad hoc networks",
            "mobile agents",
            "mobile radio",
            "telecommunication computing",
            "telecommunication security",
            "vehicles",
            "VANET",
            "ad-hoc vehicular networks",
            "intelligent agents",
            "mobile vehicular ad-hoc networks",
            "trust modeling",
            "Information exchange",
            "Traffic management",
            "Trust modeling",
            "VANET"
        ],
        "authors": [
            {
                "name": "Umar Farooq Minhas",
                "org": "David R. Cheriton Sch. of Comput. Sci., Univ. of Waterloo, Waterloo, ON, Canada|c|"
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Thomas Tran",
                "org": ""
            },
            {
                "name": "Robin Cohen",
                "org": ""
            }
        ],
        "venue": "WI-IAT), 2010 IEEE/WIC/ACM International Conference",
        "year": 2010
    },
    "RXYfbsgP": {
        "id": "RXYfbsgP",
        "title": "Towards effective recommendation of social data across social networking sites",
        "abstract": "Users of Social Networking Sites (SNSs) like Facebook, MySpace, LinkedIn, or Twitter, are often overwhelmed by the huge amount of social data (friends' updates and other activities). We propose using machine learning techniques to learn preferences of users and generate personalized recommendations. We apply four different machine learning techniques on previously rated activities and friends to generate personalized recommendations for activities that may be interesting to each user. We also use different non-textual and textual features to represent activities. The evaluation results show that good performance can be achieved when both non-textual and textual features are used, thus helping users deal with cognitive overload.",
        "keywords": [
            "different non-textual",
            "textual feature",
            "social networking site",
            "social data",
            "personalized recommendation",
            "evaluation result",
            "towards effective recommendation",
            "good performance",
            "huge amount",
            "cognitive overload",
            "social networking sites",
            "different machine",
            "users deal",
            "machine learning"
        ],
        "authors": [
            {
                "name": "Yuan Wang",
                "org": "Department of Computer Science, University of Saskatchewan, Canada"
            },
            {
                "name": "Jie Zhang",
                "org": "School of Computer Engineering, Nanyang Technological University, Singapore"
            },
            {
                "name": "Julita Vassileva",
                "org": "Department of Computer Science, University of Saskatchewan, Canada"
            }
        ],
        "venue": "AIMSA",
        "year": 2010
    },
    "jOZTwfkZ": {
        "id": "jOZTwfkZ",
        "title": "Bayesian credibility modeling for personalized recommendation in participatory media",
        "abstract": "In this paper, we focus on the challenge that users face in processing messages on the web posted in participatory media settings, such as blogs It is desirable to recommend to users a restricted set of messages that may be most valuable to them Credibility of a message is an important criteria to judge its value In our approach, theories developed in sociology, political science and information science are used to design a model for evaluating the credibility of messages that is user-specific and that is sensitive to the social network in which the user resides To recommend new messages to users, we employ Bayesian learning, built on past user behaviour, integrating new concepts of context and completeness of messages inspired from the strength of weak ties hypothesis, from social network theory We are able to demonstrate that our method is effective in providing the most credible messages to users and significantly enhances the performance of collaborative filtering recommendation, through a user study on the digg.com dataset.",
        "keywords": [
            "social network",
            "new message",
            "bayesian learning",
            "personalized recommendation",
            "past user behaviour",
            "bayesian credibility modeling",
            "social network theory",
            "user study",
            "user resides",
            "information science",
            "participatory media",
            "new concept",
            "political science",
            "collaborative filtering"
        ],
        "authors": [
            {
                "name": "Aaditeshwar Seth",
                "org": "Department of Computer Science and Engineering, IIT, Delhi, India"
            },
            {
                "name": "Jie Zhang",
                "org": "School of Computer Engineering, Nanyang Technological University, Singapore"
            },
            {
                "name": "Robin Cohen",
                "org": "School of Computer Science, University of Waterloo, Canada"
            }
        ],
        "venue": "UMAP",
        "year": 2010
    },
    "OzzIOYbf": {
        "id": "OzzIOYbf",
        "title": "Asymmetric pareto-adaptive scheme for multiobjective optimization",
        "abstract": "A core challenge of Multiobjective Evolutionary Algorithms (MOEAs) is to attain evenly distributed Pareto optimal solutions along the Pareto front. In this paper, we propose a novel asymmetric Pareto-adaptive (apa ) scheme for the identification of well distributed Pareto optimal solutions based on the geometrical characteristics of the Pareto front. The apa scheme applies to problem with symmetric and asymmetric Pareto fronts. Evaluation on multiobjective problems with Pareto fronts of different forms confirms that apa improves both convergence and diversity of the classical decomposition-based (MOEA/D) and Pareto dominance-based MOEAs (paε -MyDE).",
        "keywords": [
            "asymmetric pareto-adaptive scheme",
            "pareto optimal solution",
            "pareto front",
            "geometrical characteristic",
            "multiobjective evolutionary algorithms",
            "apa scheme",
            "novel asymmetric pareto-adaptive",
            "asymmetric pareto front",
            "different form",
            "multiobjective optimization",
            "pareto dominance-based moeas",
            "core challenge"
        ],
        "authors": [
            {
                "name": "Siwei Jiang",
                "org": "School of Computer Engineering, Nanyang Technology University, Singapore"
            },
            {
                "name": "Jie Zhang",
                "org": "School of Computer Engineering, Nanyang Technology University, Singapore"
            },
            {
                "name": "Yew Soon Ong",
                "org": "School of Computer Engineering, Nanyang Technology University, Singapore"
            }
        ],
        "venue": "Australasian Conference on Artificial Intelligence",
        "year": 2011
    },
    "PGaTdHoZ": {
        "id": "PGaTdHoZ",
        "title": "iCLUB: an integrated clustering-based approach to improve the robustness of reputation systems",
        "abstract": "The problem of unfair testimonies has to be addressed effectively to improve the robustness of reputation systems. We propose an integrated CLUstering-Based approach called iCLUB to filter unfair testimonies for reputation systems using multi-nominal testimonies, in multiagent-based electronic commerce. It adopts clustering and considers buying agents' local and global knowledge about selling agents. Experimental evaluation demonstrates promising results of our approach in filtering various types of unfair testimonies.",
        "keywords": [
            "integrated CLUstering-Based approach",
            "reputation system",
            "multiagent-based electronic commerce",
            "multi-nominal testimony",
            "integrated clustering-based approach",
            "various type",
            "experimental evaluation",
            "global knowledge",
            "unfair testimony"
        ],
        "authors": [
            {
                "name": "Siyuan Liu",
                "org": "Nanyang Technological University, Singapore"
            },
            {
                "name": "Jie Zhang",
                "org": "Nanyang Technological University, Singapore"
            },
            {
                "name": "Chunyan Miao",
                "org": "Nanyang Technological University, Singapore"
            },
            {
                "name": "Yin-Leng Theng",
                "org": "Nanyang Technological University, Singapore"
            },
            {
                "name": "Alex C. Kot",
                "org": "Nanyang Technological University, Singapore"
            }
        ],
        "venue": "AAMAS",
        "year": 2011
    },
    "12qkRm4p": {
        "id": "12qkRm4p",
        "title": "IntRank: Interaction Ranking-Based Trustworthy Friend Recommendation",
        "abstract": "Social networks are fundamental to virtual communities (e.g., forums, blogs) and virtual communities benefit from well-established social networks. As making friends with other members is a common way to establish social relationships and people need to decide whom they should trust when making friends, friend recommendation has received considerable attention in virtual communities. Towards this goal, we first formulate hypotheses on factors that influence trust and the probability of establishing friendships from various interaction attributes in virtual communities. Through experiments on real interaction and friendship data, we validate the proposed hypotheses and propose a novel interaction ranking-based trustworthy friend recommendation model called IntRank for recommending trustworthy friends to community members. Different from traditional friend recommendation mechanisms, IntRank is built on the foundation of carefully verified interaction attributes that influence trust and friendship probability in virtual communities. It is able to effectively recommend trustworthy friends as confirmed by the performance evaluation results.",
        "keywords": [],
        "authors": [
            {
                "name": "Lizi Zhang",
                "org": ""
            },
            {
                "name": "Hui Fang",
                "org": ""
            },
            {
                "name": "Wee Keong Ng",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            }
        ],
        "venue": "IEEE International Conference on Trust, Security and Privacy in Computing and Communications",
        "year": 2011
    },
    "VdAP7AVd": {
        "id": "VdAP7AVd",
        "title": "Improving PGP Web of Trust through the Expansion of Trusted Neighborhood",
        "abstract": "PGP Web of Trust where users can sign digital signatures on public key certificates of other users has been successfully applied in securing emails and files transmitted over the Internet. However, its rigorous restrictions on utilizable trust relationships and acceptable signatures limit its performance. In this paper, we first make some modification and extension to PGP Web of Trust by relaxing those constraints. In addition, we propose a novel method to further expand trusted neighborhood of users by merging the signatures of the trusted neighbors and finding the similar users based on the merged signature set. Confirmed by the experiments carried out in different simulated real-life scenarios, our method applied to both the modified and extended PGP methods can improve their performance. With the expansion of trusted neighborhood, the performance of the original PGP Web of Trust is also improved considerably.",
        "keywords": [
            "merged signature set",
            "different simulated real-life scenario",
            "improving pgp web",
            "novel method",
            "rigorous restriction",
            "original pgp web",
            "public key certificate",
            "acceptable signature",
            "extended pgp method",
            "trusted neighborhood",
            "pgp web",
            "digital signature",
            "web of trust",
            "public key",
            "merging",
            "web services",
            "internet",
            "mathematical model",
            "visualization",
            "domain knowledge",
            "natural language processing",
            "computer model",
            "iron",
            "digital signatures",
            "information retrieval",
            "public key cryptography"
        ],
        "authors": [
            {
                "name": "Guibing Guo",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Julita Vassileva",
                "org": ""
            }
        ],
        "venue": "Web Intelligence",
        "year": 2011
    },
    "IJOLHHla": {
        "id": "IJOLHHla",
        "title": "Improving PGP Web of Trust through the Expansion of Trusted Neighborhood",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "julita vassileva",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "guibing guo",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2011
    },
    "Cntn5G24": {
        "id": "Cntn5G24",
        "title": "Multiobjective optimization by decomposition with Pareto-adaptive weight vectors.",
        "abstract": "MOEA/D is a recently proposed methodology of Multiobjective Evolution Algorithms that decomposes multiobjective problems into a number of scalar subproblems and optimizes them simultaneously. However, classical MOEA/D uses same weight vectors for different shapes of Pareto front. We propose a novel method called Pareto-adaptive weight vectors (pa) to automatically adjust the weight vectors by the geometrical characteristics of Pareto front. Evaluation on different multiobjective problems confirms that the new algorithm obtains higher hypervolume, better convergence and more evenly distributed solutions than classical MOEA/D and NSGA-II. © 2011 IEEE.",
        "keywords": [
            "genetics",
            "multiobjective optimization",
            "evolutionary computation",
            "algorithm design"
        ],
        "authors": [
            {
                "name": "Siwei Jiang",
                "org": ""
            },
            {
                "name": "Zhihua Cai",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Yew-Soon Ong",
                "org": ""
            }
        ],
        "venue": "ICNC",
        "year": 2011
    },
    "imcabr9E": {
        "id": "imcabr9E",
        "title": "Improving the use of advisor networks for multi-agent trust modelling",
        "abstract": "This paper provides an approach for improving the trust modelling of users when a social network of advisors is employed (for example when advisors are recommending the most trustworthy service providers). We present three important improvements to trust modelling, two directly relating to the size of the network (through either the use of a threshold or by setting a maximum network size) and a third (advisor referrals) which focuses on ensuring that the advisors have attained an appropriate level of expertise, for the advice that they provide. Experimental results confirm the value of our methods when choosing parameters in a principled manner, leading to improvements in the accuracy of trust modelling (shown in the context of electronic marketplaces). In all, this research provides insights into how to set the size and composition of social networks, in order to effectively integrate the advice of peers when modelling the trust of users.",
        "keywords": [
            "multi-agent systems",
            "security of data",
            "social networking (online)",
            "advisor networks",
            "electronic marketplaces",
            "multiagent trust modelling",
            "social networks",
            "trustworthy service providers",
            "E-Commerce applications",
            "Multi-Agent Systems",
            "Social Networks",
            "Trust Modelling"
        ],
        "authors": [
            {
                "name": "Joshua Gorner",
                "org": "David R. Cheriton Sch. of Comput. Sci., Univ. of Waterloo, Waterloo, ON, Canada|c|"
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Robin Cohen",
                "org": ""
            }
        ],
        "venue": "Privacy, Security and Trust",
        "year": 2011
    },
    "B3tJFp9D": {
        "id": "B3tJFp9D",
        "title": "Trust Management and Admission Control for Host-Based Collaborative Intrusion Detection",
        "abstract": "The accuracy of detecting an intrusion within a network of intrusion detection systems (IDSes) depends on the efficiency of collaboration between member IDSes. The security itself within this network is an additional concern that needs to be addressed. In this paper, we present a trust-based framework for secure and effective collaboration within an intrusion detection network (IDN). In particular, we design a trust model that allows each IDS to evaluate the trustworthiness of other IDSes based on its personal experience. We also propose an admission control algorithm for the IDS to manage the acquaintances it approaches for advice about intrusions. We discuss the effectiveness of our approach in protecting the IDN against common attacks. Additionally, experimental results demonstrate that our system yields significant improvement in detecting intrusions. The trust model further improves the robustness of the collaborative system against malicious attacks. The experimental results also support that our admission control algorithm is effective and fair, and creates incentives for collaboration.",
        "keywords": [
            "Security",
            "Intrusion detection systems",
            "Acquaintance management",
            "Collaboration networks",
            "Peer-to-peer networks",
            "Insider attack",
            "Robustness"
        ],
        "authors": [
            {
                "name": "Carol Fung",
                "org": "David R. Cheriton School of Computer Science, University of Waterloo, Waterloo, Canada"
            },
            {
                "name": "Jie Zhang",
                "org": "School of Computer Engineering, Nanyang Technological University, Singapore, Singapore 639798"
            },
            {
                "name": "Issam Aib",
                "org": "David R. Cheriton School of Computer Science, University of Waterloo, Waterloo, Canada"
            },
            {
                "name": "Raouf Boutaba",
                "org": "David R. Cheriton School of Computer Science, University of Waterloo, Waterloo, Canada"
            }
        ],
        "venue": "J. Network Syst. Manage.",
        "year": 2011
    },
    "kA58FCxr": {
        "id": "kA58FCxr",
        "title": "Design of a multiagent-based e-marketplace to secure service trading on the internet",
        "abstract": "Electronic marketplaces are not always easily regulated using traditional legal systems. As a result, suitable dispute prevention and resolution mechanisms for electronic marketplaces are of interest to design. In this paper, we design a multiagent-based e-marketplace where participants represented by autonomous software agents may be egocentric, strategic and even malicious. Our marketplace focuses on trading arbitrable and replicatable services, such as computational resources and data storage, over the Internet. We propose a novel dispute prevention and resolution mechanism that is theoretically proven to be able to induce good conduct for marketplace participants. Our marketplace also features cost-effectiveness, robustness and budget balance.",
        "keywords": [
            "novel dispute prevention",
            "marketplace participant",
            "electronic marketplace",
            "computational resource",
            "suitable dispute prevention",
            "autonomous software agent",
            "resolution mechanism",
            "good conduct",
            "multiagent-based e-marketplace",
            "budget balance",
            "data storage",
            "service trading"
        ],
        "authors": [
            {
                "name": "Qin Li",
                "org": "University of London"
            },
            {
                "name": "Keith M. Martin",
                "org": "University of London"
            },
            {
                "name": "Jie Zhang",
                "org": "Nanyang Technological University Singapore"
            }
        ],
        "venue": "Proceedings of the 13th International Conference on Electronic Commerce",
        "year": 2011
    },
    "cnWpm9Xd": {
        "id": "cnWpm9Xd",
        "title": "Design of a reputation system based on dynamic coalition formation",
        "abstract": "Reputation systems bear some challenging problems where buyers have different subjectivity in evaluating their experience with sellers and they may not have incentives to share their experience. In this paper, we propose a novel reputation system based on dynamic coalition formation where buyers with similar subjectivity and rich experience will be awarded virtual credits for helping others find trustworthy sellers to successfully conduct business. Our theoretical analysis confirms that the coalitions formed in this way are stable.",
        "keywords": [
            "reputation system",
            "different subjectivity",
            "dynamic coalition formation",
            "virtual credit",
            "similar subjectivity",
            "challenging problem",
            "rich experience",
            "novel reputation system",
            "trustworthy seller",
            "theoretical analysis"
        ],
        "authors": [
            {
                "name": "Yuan Liu",
                "org": "School of Computer Engineering, Nanyang Technological University, Singapore"
            },
            {
                "name": "Jie Zhang",
                "org": "School of Computer Engineering, Nanyang Technological University, Singapore"
            },
            {
                "name": "Quanyan Zhu",
                "org": "Department of Electrical and Computer Engineering, UIUC"
            }
        ],
        "venue": "SocInfo",
        "year": 2011
    },
    "pM4g15d6": {
        "id": "pM4g15d6",
        "title": "Collaborative Approaches to Complementing Qualitative Preferences of Agents for Effective Service Selection",
        "abstract": "Incomplete preferences of agents may render service selection ineffective. We address this problem by proposing a set of collaborative approaches to complementing agents' incomplete preferences in a qualitative way. For an agent, the approaches first find its similar agents, and then base the similar agents' qualitative preferences to complement this agent's missing preferences. We analyze and compare these approaches and provide experimental results to justify our arguments. We also compare our approach with the classic collaborative filtering and show the competitive advantages of our approach in service selection. Our work thus serves as an important step towards effective service selection.",
        "keywords": [
            "qualitative preference",
            "complementing agent",
            "collaborative approaches",
            "effective service selection",
            "collaborative approach",
            "complementing qualitative preferences",
            "incomplete preference",
            "competitive advantage",
            "service selection",
            "similar agent",
            "classic collaborative",
            "collaboration",
            "groupware",
            "mathematical model",
            "collaborative filtering",
            "clustering algorithms"
        ],
        "authors": [
            {
                "name": "Hongbing Wang",
                "org": "Southeast University(Southeast University,Southeast Univ),Nanjing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Nanyang Technological University School of Computer Engineering(Nanyang Technological University),Singapore City,Singapore"
            },
            {
                "name": "Yangyu Tang",
                "org": "Southeast University(Southeast University,Southeast Univ),Nanjing,China"
            },
            {
                "name": "Shizhi Shao",
                "org": "Southeast University(Southeast University,Southeast Univ),Nanjing,China"
            }
        ],
        "venue": "ICTAI",
        "year": 2011
    },
    "DQgNsFTR": {
        "id": "DQgNsFTR",
        "title": "Extensive experimental validation of a personalized approach for coping with unfair ratings in reputation systems",
        "abstract": "The unfair rating problem exists when a buying agent models the trustworthiness of selling agents by also relying on ratings of the sellers from other buyers in electronic marketplaces, that is in a reputation system. In this article, we first analyze the capabilities of existing approaches for coping with unfair ratings in different challenging scenarios, including ones where the majority of buyers are dishonest, buyers lack personal experience with sellers, sellers may vary their behavior, and buyers may provide a large number of ratings. We then present a personalized modeling approach (PMA) that has all these capabilities. Our approach allows a buyer to model both the private reputation and public reputation of other buyers to determine whether these buyers' ratings are fair. More importantly, in this work, we focus on experimental comparison of our approach with two key models in a simulated dynamic e-marketplace environment. We specifically examine the above mentioned scenarios to confirm our analysis and to demonstrate the capabilities of our approach. Our study thus provides the extensive experimental support for the personalized approach that can be effectively employed by reputation systems to cope with unfair ratings.",
        "keywords": [
            "reputation system",
            "unfair rating problem",
            "public reputation",
            "personalized approach",
            "extensive experimental support",
            "experimental comparison",
            "personalized modeling approach",
            "private reputation",
            "unfair rating",
            "extensive experimental validation",
            "buying agent model",
            "multi agent systems"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Nanyang Technological University, School of Computer Engineering"
            }
        ],
        "venue": "JTAER",
        "year": 2011
    },
    "jMfMlS2Q": {
        "id": "jMfMlS2Q",
        "title": "Trust, reputation and user modeling",
        "abstract": "The Trust, Reputation and User Modeling (TRUM) workshop (http://madmuc.usask.ca/WS-TRUM/) pursued the following objectives: To bring researchers together from the communities of trust and reputation modeling and user modeling; To initiate and facilitate discussions on the new trends in trust, reputation and user modeling, and to move the trends forward; To provide a forum for cutting-age research. Eleven papers were submitted to the workshop. Each submitted paper was carefully reviewed by at least 3 committee members. Finally, seven papers were accepted, including four full papers (12 pages), 2 short papers (8 pages), and 1 poster paper (3 pages + a poster). These high quality papers provide thoughtful discussions on different issues of trust and reputation modeling. They also touch upon the different aspects of user modeling, reflecting the strong connections between trust / reputation modeling and user modeling. All seven accepted papers were invited the postworkshop proceedings and six of them were submitted.",
        "keywords": [
            "high quality paper",
            "different aspect",
            "user modeling",
            "different issue",
            "eleven paper",
            "short paper",
            "accepted paper",
            "reputation modeling",
            "poster paper",
            "full paper"
        ],
        "authors": [
            {
                "name": "Julita Vassileva",
                "org": "University of Saskatchewan, Canada"
            },
            {
                "name": "Jie Zhang",
                "org": "Nanyang Technological University, Singapore"
            }
        ],
        "venue": "UMAP Workshops",
        "year": 2011
    },
    "asbKWbqY": {
        "id": "asbKWbqY",
        "title": "Handling subjective user feedback for reputation computation in virtual reality",
        "abstract": "As the interest in virtual reality is growing both from academia and industry, its new application areas emerge, one of which is the virtual marketplaces. We have previously proposed that buyers may share their experience with sellers in virtual marketplaces by exchanging their feedback. The feedback is composed of terms describing merchandise based on the users' five senses. However, some of these terms (e.g., soft) may be subjective and have different semantics for different buyers. Thus, alignment of the feedback containing subjective terms becomes an indispensable step before using exchanged feedback for reputation computations. In this paper, we propose a novel approach to align subjectivity in user feedback for reputation computation in virtual marketplaces. We demonstrate how sensory data in virtual reality can be exploited to handle subjectivity and describe how the aligned feedback can be used in seller reputation computation.",
        "keywords": [
            "subjective term",
            "seller reputation computation",
            "different semantics",
            "subjective user feedback",
            "new application area",
            "indispensable step",
            "virtual reality",
            "reputation computation",
            "virtual marketplace",
            "user feedback",
            "different buyer"
        ],
        "authors": [
            {
                "name": "Hui Fang",
                "org": "Institute for Media Innovation & School of Computer Engineering, Nanyang Technological University, Singapore"
            },
            {
                "name": "Murat Şensoy",
                "org": "Department of Computing Science, University of Aberdeen, United Kingdom"
            },
            {
                "name": "Jie Zhang",
                "org": "Institute for Media Innovation & School of Computer Engineering, Nanyang Technological University, Singapore"
            },
            {
                "name": "Nadia Magnenat Thalmann",
                "org": "Institute for Media Innovation & School of Computer Engineering, Nanyang Technological University, Singapore"
            }
        ],
        "venue": "UMAP Workshops",
        "year": 2011
    },
    "pxSSkibO": {
        "id": "pxSSkibO",
        "title": "The influence of interaction attributes on trust in virtual communities",
        "abstract": "In virtual communities (e.g., forums, blogs), modeling the trust of community members is an effective way to help members make decisions about whose information is more valuable. Towards this goal, we first formulate hypotheses on how various interaction attributes influence trust in virtual communities, and validate these hypotheses through experiments on real data. The influential attributes are then used to develop a trust ranking-based recommendation model called TruRank for recommending the most trustworthy community members. Contrary to traditional recommender systems that rely heavily on subjective manual feedback, our model is built on the foundation of carefully verified objective interaction attributes in virtual communities.",
        "keywords": [
            "community member",
            "trustworthy community member",
            "virtual community",
            "trust ranking-based recommendation model",
            "various interaction",
            "influential attribute",
            "objective interaction attribute",
            "subjective manual feedback",
            "influence trust",
            "recommender system",
            "trust"
        ],
        "authors": [
            {
                "name": "Lizi Zhang",
                "org": "School of Computer Engineering, Nanyang Technological University, Singapore"
            },
            {
                "name": "Cheun Pin Tan",
                "org": "School of Computer Engineering, Nanyang Technological University, Singapore"
            },
            {
                "name": "Siyi Li",
                "org": "School of Computer Engineering, Nanyang Technological University, Singapore"
            },
            {
                "name": "Hui Fang",
                "org": "School of Computer Engineering, Nanyang Technological University, Singapore"
            },
            {
                "name": "Pramodh Rai",
                "org": "School of Computer Engineering, Nanyang Technological University, Singapore"
            },
            {
                "name": "Yao Chen",
                "org": "School of Computer Engineering, Nanyang Technological University, Singapore"
            },
            {
                "name": "Rohit Luthra",
                "org": "School of Computer Engineering, Nanyang Technological University, Singapore"
            },
            {
                "name": "Wee Keong Ng",
                "org": "School of Computer Engineering, Nanyang Technological University, Singapore"
            },
            {
                "name": "Jie Zhang",
                "org": "School of Computer Engineering, Nanyang Technological University, Singapore"
            }
        ],
        "venue": "UMAP Workshops",
        "year": 2011
    },
    "OrqW2tYa": {
        "id": "OrqW2tYa",
        "title": "Service Selection Based on Similarity Measurement for Conditional Qualitative Preference.",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Hongbing Wang",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Hualan Wang",
                "org": ""
            },
            {
                "name": "Yangyu Tang",
                "org": ""
            },
            {
                "name": "Guibing Guo",
                "org": ""
            }
        ],
        "venue": "Web Intelligence",
        "year": 2012
    },
    "juItcVGC": {
        "id": "juItcVGC",
        "title": "WCP-Nets: a weighted extension to CP-Nets for web service selection",
        "abstract": "User preference often plays a key role in personalized applications such as web service selection. CP-nets is a compact and intuitive formalism for representing and reasoning with conditional preferences. However, the original CP-nets does not support fine-grained preferences, which results in the inability to compare certain preference combinations (service patterns). In this paper, we propose a weighted extension to CP-nets called WCP-nets by allowing users to specify the relative importance (weights) between attribute values and between attributes. Both linear and nonlinear methods are proposed to adjust the attribute weights when conflicts between users' explicit preferences and their actual behaviors of service selection occur. Experimental results based on two real datasets show that our method can effectively enhance the expressiveness of user preference and select more accurate services than other counterparts.",
        "keywords": [
            "weighted extension",
            "user preference",
            "fine-grained preference",
            "original cp-nets",
            "explicit preference",
            "web service selection",
            "conditional preference",
            "certain preference combination",
            "service selection",
            "accurate service",
            "service pattern"
        ],
        "authors": [
            {
                "name": "Hongbing Wang",
                "org": "School of Computer Science and Engineering, Southeast University, Nanjing, China"
            },
            {
                "name": "Jie Zhang",
                "org": "School of Computer Engineering, Nanyang Technological University, Singapore"
            },
            {
                "name": "Wenlong Sun",
                "org": "School of Computer Science and Engineering, Southeast University, Nanjing, China"
            },
            {
                "name": "Hongye Song",
                "org": "School of Computer Science and Engineering, Southeast University, Nanjing, China"
            },
            {
                "name": "Guibing Guo",
                "org": "School of Computer Engineering, Nanyang Technological University, Singapore"
            },
            {
                "name": "Xiang Zhou",
                "org": "School of Computer Science and Engineering, Southeast University, Nanjing, China"
            }
        ],
        "venue": "ICSOC",
        "year": 2012
    },
    "XGEGf4Ea": {
        "id": "XGEGf4Ea",
        "title": "A Context-Aware Framework for Detecting Unfair Ratings in an Unknown Real Environment",
        "abstract": "Reputation systems are highly prone to unfair rating attacks. Though many approaches for detecting unfair ratings have been proposed so far, their performance is often affected by the environment where they are applied. For a given unknown real environment, it is difficult to choose the most suitable approach for detecting unfair ratings as the ground truth data necessary to evaluate the accuracy of the detection approaches remains unknown. In this paper, we propose a novel Context-AwaRE (CARE) framework, to choose the most suitable unfair rating detection approach for a given unknown real environment. The framework first identifies simulated environments, closely similar to that of the unknown environment. The detection approaches performing well in the most similar simulated environments are then chosen as the suitable ones for the unknown real environment. Detailed experiments illustrate that the CARE framework can choose the most suitable detection approach to accurately distinguish fair and unfair ratings for any given unknown environment.",
        "keywords": [
            "care framework",
            "unknown real environment",
            "suitable approach",
            "unfair rating attacks",
            "unfair rating",
            "simulated environment",
            "suitable unfair rating detection",
            "reputation systems",
            "detection approach",
            "similar simulated environment",
            "ubiquitous computing",
            "unfair rating attack",
            "unfair rating detection",
            "suitable detection approach",
            "context-aware framework",
            "detecting unfair ratings",
            "unknown environment",
            "security of data",
            "web intelligence",
            "latent dirichlet allocation"
        ],
        "authors": [
            {
                "name": "Cheng Wan",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Athirai A. Irissappane",
                "org": ""
            }
        ],
        "venue": "Web Intelligence",
        "year": 2012
    },
    "vgoUXjNq": {
        "id": "vgoUXjNq",
        "title": "SARC: Subjectivity Alignment for Reputation Computation (Extended Abstract)",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "hui fang",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "nadia magnenat thalmann",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2012
    },
    "FJZWQOP2": {
        "id": "FJZWQOP2",
        "title": "A simple but effective method to incorporate trusted neighbors in recommender systems",
        "abstract": "Providing high quality recommendations is important for online systems to assist users who face a vast number of choices in making effective selection decisions. Collaborative filtering is a widely accepted technique to provide recommendations based on ratings of similar users. But it suffers from several issues like data sparsity and cold start. To address these issues, in this paper, we propose a simple but effective method, namely \"Merge\", to incorporate social trust information (i.e. trusted neighbors explicitly specified by users) in providing recommendations. More specifically, ratings of a user's trusted neighbors are merged to represent the preference of the user and to find similar other users for generating recommendations. Experimental results based on three real data sets demonstrate that our method is more effective than other approaches, both in accuracy and coverage of recommendations.",
        "keywords": [
            "accepted technique",
            "effective selection decision",
            "cold start",
            "effective method",
            "recommender system",
            "online system",
            "data sparsity",
            "high quality recommendation",
            "similar user",
            "collaborative filtering"
        ],
        "authors": [
            {
                "name": "Guibing Guo",
                "org": "School of Computer Engineering, Nanyang Technological University, Singapore"
            },
            {
                "name": "Jie Zhang",
                "org": "School of Computer Engineering, Nanyang Technological University, Singapore"
            },
            {
                "name": "Daniel Thalmann",
                "org": "School of Computer Engineering, Nanyang Technological University, Singapore"
            }
        ],
        "venue": "UMAP",
        "year": 2012
    },
    "9RP1kXG2": {
        "id": "9RP1kXG2",
        "title": "Robustness of Trust Models and Combinations for Handling Unfair Ratings.",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Lizi Zhang",
                "org": ""
            },
            {
                "name": "Siwei Jiang",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Wee Keong Ng",
                "org": ""
            }
        ],
        "venue": "IFIPTM",
        "year": 2012
    },
    "y8Bg8u1x": {
        "id": "y8Bg8u1x",
        "title": "Towards a comprehensive testbed to evaluate the robustness of reputation systems against unfair rating attack.",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Athirai Aravazhi Irissappane",
                "org": ""
            },
            {
                "name": "Siwei Jiang",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            }
        ],
        "venue": "UMAP Workshops",
        "year": 2012
    },
    "DifBFgEc": {
        "id": "DifBFgEc",
        "title": "A framework for modeling trustworthiness of users in mobile vehicular ad-hoc networks and its validation through simulated traffic flow",
        "abstract": "In this paper, we present an approach for modeling user trustworthiness when traffic information is exchanged between vehicles in transportation environments. Our multi-faceted approach to trust modeling combines priority-based, role-based and experience-based trust, integrated with a majority consensus model influenced by time and location, for effective route planning. The proposed representation for the user model is outlined in detail (integrating ontological and propositional elements) and the algorithm for updating trust values is presented as well. This trust modeling framework is validated in detail through an extensive simulation testbed that models vehicle route planning. We are able to show decreased average path time for vehicles when all facets of our trust model are employed in unison. Included is an interesting confirmation of the value of distinguishing direct and indirect observations of users.",
        "keywords": [
            "trust value",
            "trust modeling framework",
            "mobile vehicular ad-hoc network",
            "average path time",
            "models vehicle route planning",
            "simulated traffic flow",
            "majority consensus model",
            "trust model",
            "experience-based trust",
            "multi-faceted approach",
            "effective route planning",
            "user model",
            "vehicle routing",
            "vehicular ad hoc network",
            "traffic flow",
            "matrix factorization"
        ],
        "authors": [
            {
                "name": "John Finnson",
                "org": "U. Waterloo, Canada"
            },
            {
                "name": "Jie Zhang",
                "org": "Nanyang Tech. U., Singapore"
            },
            {
                "name": "Thomas Tran",
                "org": "U. Ottawa, Canada"
            },
            {
                "name": "Umar Farooq Minhas",
                "org": "U. Waterloo, Canada"
            },
            {
                "name": "Robin Cohen",
                "org": "U. Waterloo, Canada"
            }
        ],
        "venue": "UMAP",
        "year": 2012
    },
    "nE8Ivsdm": {
        "id": "nE8Ivsdm",
        "title": "Combining Trust Modeling And Mechanism Design For Promoting Honesty In E-Marketplaces",
        "abstract": "In this paper, we propose a novel incentive mechanism for promoting honesty in electronic marketplaces that is based on trust modeling. In our mechanism, buyers model other buyers and select the most trustworthy ones as their neighbors to form a social network which can be used to ask advice about sellers. In addition, however, sellers model the reputation of buyers based on the social network. Reputable buyers provide truthful ratings for sellers, and are likely to be neighbors of many other buyers. Sellers will provide more attractive products to reputable buyer to build their own reputation. We theoretically prove that a marketplace operating with our mechanism leads to greater profit both for honest buyers and honest sellers. We emphasize the value of our approach through a series of illustrative examples and in direct contrast to other frameworks for addressing agent trustworthiness. In all, we offer an effective approach for the design of e-marketplaces that is attractive to users, through its promotion of honesty. © 2012 Wiley Periodicals, Inc.",
        "keywords": [
            "social network",
            "honest seller",
            "effective approach",
            "novel incentive mechanism",
            "sellers model",
            "wiley periodicals",
            "honest buyer",
            "combining trust modeling",
            "own reputation",
            "mechanism design",
            "attractive product",
            "reputable buyer",
            "promoting honesty"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "<span> <sup>1</sup> <i>School of Computer Engineering, Nanyang Technological University, Singapore</i> </span> <span><sup>2</sup><i>School of Computer Science, University  ..."
            },
            {
                "name": "Robin Cohen",
                "org": "<span> <sup>1</sup> <i>School of Computer Engineering, Nanyang Technological University, Singapore</i> </span> <span><sup>2</sup><i>School of Computer Science, University  ..."
            },
            {
                "name": "Kate Larson",
                "org": "<span> <sup>1</sup> <i>School of Computer Engineering, Nanyang Technological University, Singapore</i> </span> <span><sup>2</sup><i>School of Computer Science, University  ..."
            }
        ],
        "venue": "Computational Intelligence",
        "year": 2012
    },
    "s02dR9z1": {
        "id": "s02dR9z1",
        "title": "Reasoning about user trustworthiness with non-binary advice from peers.",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "John Finnson",
                "org": ""
            },
            {
                "name": "Robin Cohen",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Thomas T. Tran",
                "org": ""
            },
            {
                "name": "Umar Farooq Minhas",
                "org": ""
            }
        ],
        "venue": "UMAP Workshops",
        "year": 2012
    },
    "BMq93L1E": {
        "id": "BMq93L1E",
        "title": "Trust Management for VANETs: Challenges, Desired Properties and Future Directions",
        "abstract": "An increasingly large number of cars are being equipped with GPS and Wi-Fi devices, forming vehicular ad-hoc networks VANETs and enabling vehicle to vehicle communication with the goal of providing increased passenger and road safety. However, dishonest peers vehicles in a VANET may send out false information to maximize their own utility. Given the dire consequences of acting on false information in this context, there is a serious need to establish trust among peers. This article first discusses the challenges for trust management caused by the important characteristics of VANET environments, and identifies desired properties that effective trust management should incorporate in order to address the challenges. The author then surveys and evaluates existing trust models in VANETs, and points out that none of the trust models has achieved all the properties. Finally, the author proposes some important future directions for research towards effective trust management for VANETs.",
        "keywords": [
            "important characteristic",
            "vehicular ad-hoc networks vanets",
            "desired properties",
            "dishonest peers vehicle",
            "effective trust management",
            "future directions",
            "trust management",
            "enabling vehicle",
            "vanet environment",
            "trust model",
            "false information",
            "important future direction",
            "vehicular ad hoc network"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Nanyang Technological University, Singapore"
            }
        ],
        "venue": "IJDST",
        "year": 2012
    },
    "XRPmPUne": {
        "id": "XRPmPUne",
        "title": "SARC: subjectivity alignment for reputation computation",
        "abstract": "Current deployed reputation systems simply aggregate numerical ratings provided by buyers, but overlook the buyers' subjectivity difference in evaluating the transactions with a seller. To address this problem, we propose a subjectivity alignment approach for reputation computation (SARC).",
        "keywords": [
            "reputation system",
            "subjectivity difference",
            "reputation computation",
            "subjectivity alignment approach",
            "aggregate numerical rating",
            "bayesian learning"
        ],
        "authors": [
            {
                "name": "Hui Fang",
                "org": "Nanyang Technological University, Singapore"
            },
            {
                "name": "Jie Zhang",
                "org": "Nanyang Technological University, Singapore"
            },
            {
                "name": "Murat Şensoy",
                "org": "University of Aberdeen, United Kingdom"
            },
            {
                "name": "Nadia M. Thalmann",
                "org": "Nanyang Technological University, Singapore"
            }
        ],
        "venue": "AAMAS",
        "year": 2012
    },
    "Z5rVZrKH": {
        "id": "Z5rVZrKH",
        "title": "Design of an incentive mechanism to promote honesty in e-marketplaces with limited inventory",
        "abstract": "In e-marketplaces with limited inventory where buyers' demand is larger than sellers' supply, promoting honesty raises new challenges: sellers may behave dishonestly because they can sell out all products without the necessity of gaining high reputation; buyers may provide untruthful ratings to mislead other buyers in order to have a higher chance to obtain the limited products. In this paper, we propose a novel incentive mechanism to promote honesty in such e-marketplaces. More specifically, our mechanism models both buyer and seller honesty. It offers higher prices to the products provided by honest sellers so that the sellers can gain more profit. Honest buyers also have a higher chance to do business with honest sellers and are able to gain more utility. Theoretical analysis and experimental results show that our mechanism promotes both buyer and seller honesty. Finally, we address the re-entry problem by imposing membership fees on new sellers. We show that the membership fee can discourage sellers from re-entry both in theoretical analysis and experimental validation.",
        "keywords": [
            "novel incentive mechanism",
            "honest seller",
            "honest buyer",
            "higher price",
            "higher chance",
            "mechanism model",
            "limited inventory",
            "seller honesty",
            "theoretical analysis",
            "membership fee",
            "profitability"
        ],
        "authors": [
            {
                "name": "Yuan Liu",
                "org": "Nanyang Technological University, Singapore"
            },
            {
                "name": "Jie Zhang",
                "org": "Nanyang Technological University, Singapore"
            },
            {
                "name": "Qin Li",
                "org": "Nanyang Technological University, Singapore"
            }
        ],
        "venue": "ICEC",
        "year": 2012
    },
    "FaawnqeC": {
        "id": "FaawnqeC",
        "title": "A multiagent evolutionary framework based on trust for multiobjective optimization",
        "abstract": "In an Evolutionary Algorithm (EA) for optimization problems, candidate solutions to the problems are individuals in a population. They produce offsprings by taking evolutionary operators with user-specific control parameters. The challenge is then how to effectively select evolutionary operators and adjust control parameters from generation to generation and on different problems. We propose a novel multiagent evolutionary framework based on trust where each solution is represented as an intelligent agent, and evolutionary operators and control parameters are represented as services. Agents select services in each generation based on trust that measures the competency or suitability of the services for solving particular problems. Multiobjective Optimization Problems (MOPs) are used to showcase the value of our framework. Experimental studies on 35 benchmark MOPs show that our framework significantly improves the performance of the state-of-the-art EAs.",
        "keywords": [
            "user-specific control parameter",
            "candidate solution",
            "agents select service",
            "evolutionary operator",
            "control parameter",
            "benchmark mops",
            "multiobjective optimization problems",
            "evolutionary algorithm",
            "different problem",
            "novel multiagent evolutionary framework",
            "multiobjective optimization",
            "multiagent systems"
        ],
        "authors": [
            {
                "name": "Siwei Jiang",
                "org": "Nanyang Technological University, Singapore"
            },
            {
                "name": "Jie Zhang",
                "org": "Nanyang Technological University, Singapore"
            },
            {
                "name": "Yew Soon Ong",
                "org": "Nanyang Technological University, Singapore"
            }
        ],
        "venue": "AAMAS",
        "year": 2012
    },
    "QNw3Fr4s": {
        "id": "QNw3Fr4s",
        "title": "Personalized Recommendation of Integrated Social Data across Social Networking Sites",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "yuan wang",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "julita vassileva",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2013
    },
    "72eoOVCC": {
        "id": "72eoOVCC",
        "title": "Towards effective online review systems in the Chinese context: A cross-cultural empirical study.",
        "abstract": "Online reviews, as one kind of quality indicator of products or service, are becoming increasingly important in influencing purchase decisions of prospective consumers on electronic commerce websites. With the fast growth of the Chinese e-commerce industry, it is thus indispensable to design effective online review systems for e-commerce websites in the Chinese context, by taking into account cultural factors. In this paper, we conduct two empirical studies on online reviews. Firstly, we study how culture differences across countries (i.e.; China and the USA) impact the way in which consumers provide online reviews. Secondly, we investigate the impact of online reviews on product sales in the Chinese context, and show that directly copying the ideas of successful online review systems in the USA will deteriorate the effectiveness of the systems in China. Finally, we propose several suggestions for the development of effective online review systems in the Chinese context based on the results of our two empirical studies and the findings in previous studies. © 2013 Elsevier B.V. © 2013 Published by Elsevier B.V.",
        "keywords": [
            "cross-cultural study",
            "electronic commerce",
            "empirical analysis",
            "national culture difference",
            "online review system"
        ],
        "authors": [
            {
                "name": "Hui Fang",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Yang Bao",
                "org": ""
            },
            {
                "name": "Qinghua Zhu",
                "org": ""
            }
        ],
        "venue": "Electronic Commerce Research and Applications",
        "year": 2013
    },
    "zOBEwKbG": {
        "id": "zOBEwKbG",
        "title": "TRUM 2013: The Role and Importance of Trust in User Modelling",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "surya nepal",
                "org": ""
            },
            {
                "name": "cecile paris",
                "org": ""
            },
            {
                "name": "julita vassileva",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2013
    },
    "x6941q31": {
        "id": "x6941q31",
        "title": "A novel Bayesian similarity measure for recommender systems",
        "abstract": "Collaborative filtering, a widely-used user-centric recommendation technique, predicts an item's rating by aggregating its ratings from similar users. User similarity is usually calculated by cosine similarity or Pearson correlation coefficient. However, both of them consider only the direction of rating vectors, and suffer from a range of drawbacks. To solve these issues, we propose a novel Bayesian similarity measure based on the Dirichlet distribution, taking into consideration both the direction and length of rating vectors. Further, our principled method reduces correlation due to chance. Experimental results on six real-world data sets show that our method achieves superior accuracy.",
        "keywords": [
            "novel bayesian similarity measure",
            "dirichlet distribution",
            "recommender system",
            "principled method",
            "user similarity",
            "pearson correlation coefficient",
            "rating vector",
            "cosine similarity",
            "real-world data set",
            "similar user"
        ],
        "authors": [
            {
                "name": "Guibing Guo",
                "org": "Nanyang Technological University, Singapore"
            },
            {
                "name": "Jie Zhang",
                "org": "Nanyang Technological University, Singapore"
            },
            {
                "name": "Neil Yorke-Smith",
                "org": "American University of Beirut, Lebanon, and University of Cambridge, UK and Nanyang Technological University, Singapore"
            }
        ],
        "venue": "IJCAI",
        "year": 2013
    },
    "MBwkUkxP": {
        "id": "MBwkUkxP",
        "title": "Towards a Comprehensive Testbed to Evaluate the Robustness of Reputation Systems against Unfair Rating Attacks",
        "abstract": "",
        "keywords": [
            "robustness",
            "testbed"
        ],
        "authors": [
            {
                "name": "siwei jiang",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2013
    },
    "xsIHyKQj": {
        "id": "xsIHyKQj",
        "title": "SocConnect: A personalized social network aggregator and recommender",
        "abstract": "Users of Social Networking Sites (SNSs) like Facebook, LinkedIn or Twitter, are facing two problems: (1) it is difficult for them to keep track of their social friendships and friends' social activities scattered across different SNSs; and (2) they are often overwhelmed by the huge amount of social data (friends' updates and other activities). To address these two problems, we propose a user-centric system called ''SocConnect'' (Social Connect) for aggregating social data from different SNSs and allowing users to create personalized social and semantic contexts for their social data. Users can blend and group friends on different SNSs, and rate the friends and their activities as favourite, neutral or disliked. SocConnect then provides personalized recommendation of friends' activities that may be interesting to each user, using machine learning techniques. A prototype is also implemented to demonstrate these functionalities of SocConnect. Evaluation on real users confirms that users generally like the proposed functionalities of our system, and machine learning can be effectively applied to provide personalized recommendation of friends' activities and help users deal with cognitive overload.",
        "keywords": [
            "proposed functionalities",
            "personalized recommendation",
            "social data",
            "machine learning",
            "different snss",
            "social networking sites",
            "social activity",
            "social connect",
            "users deal",
            "social friendship",
            "personalized social network aggregator"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "School of Computer Engineering, Nanyang Technological University, Singapore"
            },
            {
                "name": "Yuan Wang",
                "org": "Department of Computer Science, University of Saskatchewan, Canada"
            },
            {
                "name": "Julita Vassileva",
                "org": "Department of Computer Science, University of Saskatchewan, Canada"
            }
        ],
        "venue": "Inf. Process. Manage.",
        "year": 2013
    },
    "90jbL6pP": {
        "id": "90jbL6pP",
        "title": "Qualitative preference-based service selection for multiple agents",
        "abstract": "Service selection is one of the important problems in applications of multi-agent systems. A qualitative way is desirable for service selection according to agents' preferences on non-functional Quality of Service QoS attributes of services. However, it is challenging when the decision has to be made for multiple agents with preferences on attributes that may be incomplete. In this paper, first use a qualitative graphical representation tool called CP-nets to describe preference relations in a relatively compact, intuitive and structured manner. We then propose a preference reasoning algorithm to construct a derivation tree from a CP-net for each agent and then generate all service patterns for this agent. The Rank semantic is used together with the Lex semantic to provide the ordering of different service patterns. After that, we merge ranked service patterns for all agents and select a set of services that satisfy these agents the most. Finally, we also propose a semantic validation algorithm to show the satisfactory degree of the best service patterns according to other voting semantics. Experimental results indicate that this method can always obtain optimal outcomes which closely satisfy all agents, within acceptable execution time.",
        "keywords": [
            "lex semantic",
            "qualitative preference-based service selection",
            "different service pattern",
            "rank semantic",
            "preference relation",
            "best service pattern",
            "preference reasoning algorithm",
            "multiple agent",
            "semantic validation algorithm",
            "service selection",
            "service pattern"
        ],
        "authors": [
            {
                "name": "Hongbing Wang",
                "org": "School of Science and Engineering, Southeast University, China"
            },
            {
                "name": "Jie Zhang",
                "org": "School of Computer Engineering, Nanyang Technological University, Singapore. E-mail: zhangj@ntu.edu.sg"
            },
            {
                "name": "Cheng Wan",
                "org": "School of Science and Engineering, Southeast University, China and Department of Healthcare Informatics, Nanjing Medical University, China"
            },
            {
                "name": "Shizhi Shao",
                "org": "School of Science and Engineering, Southeast University, China"
            },
            {
                "name": "Robin Cohen",
                "org": "School of Computer Science, University of Waterloo, Canada. E-mail: rcohen@cs.uwaterloo.ca"
            }
        ],
        "venue": "Web Intelligence and Agent Systems",
        "year": 2013
    },
    "cFk6qDgQ": {
        "id": "cFk6qDgQ",
        "title": "Trust modeling for message relay control and local action decision making in VANETs",
        "abstract": "In this paper, we present a trust-modeling framework for message propagation and evaluation in vehicular ad hoc networks. In the framework, peers share information regarding road condition or safety, and others provide opinions about whether the information can be trusted. More specifically, our trust-based message propagation model collects and propagates peers' opinions in an efficient, secure, and scalable way by dynamically controlling information dissemination. The trust-based message evaluation model allows peers to derive a local action decision about whether to follow the information by evaluating the information in a distributed and collaborative fashion while taking into account others' opinions. Experimental results demonstrate that our proposed trust-modeling framework promotes network scalability and system effectiveness, which are the two essentially important factors for the popularization of vehicular ad hoc networks, in information propagation and evaluation under the pervasive presence of false information. In particular, we clarify how our relay control serves to decrease the number of inappropriate actions taken on the basis of malicious information and enables honest peers to produce a greater number of deliveries within the network. Copyright © 2012 John Wiley & Sons, Ltd.",
        "keywords": [
            "trust management",
            "vehicular ad hoc networks",
            "road safety and congestion",
            "message relay control",
            "local action decision making"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "School of Computer Engineering, Nanyang Technological University, Singapore, Singapore"
            },
            {
                "name": "Chen Chen",
                "org": "David R. Cheriton School of Computer Science, University of Waterloo, Waterloo, Canada"
            },
            {
                "name": "Robin Cohen",
                "org": "David R. Cheriton School of Computer Science, University of Waterloo, Waterloo, Canada"
            }
        ],
        "venue": "Security and Communication Networks",
        "year": 2013
    },
    "5Uesw8Kp": {
        "id": "5Uesw8Kp",
        "title": "Prior ratings: a new information source for recommender systems in e-commerce",
        "abstract": "Lack of motivation to provide ratings and eligibility to rate generally only after purchase restrain the effectiveness of recommender systems and contribute to the well-known data sparsity and cold start problems. This paper proposes a new information source for recommender systems, called prior ratings. Prior ratings are based on users' experiences of virtual products in a mediated environment, and they can be submitted prior to purchase. A conceptual model of prior ratings is proposed, integrating the environmental factor presence whose effects on product evaluation have not been studied previously. A user study conducted in website and virtual store modalities demonstrates the validity of the conceptual model, in that users are more willing and confident to provide prior ratings in virtual environments.",
        "keywords": [
            "prior rating",
            "cold start problem",
            "virtual environment",
            "new information source",
            "recommender system",
            "mediated environment",
            "virtual store modality",
            "environmental factor presence",
            "conceptual model",
            "virtual product",
            "recommender systems",
            "cold start"
        ],
        "authors": [
            {
                "name": "Guibing Guo",
                "org": "Nanyang Technological University, Singapore, Singapore"
            },
            {
                "name": "Jie Zhang",
                "org": "Nanyang Technological University, Singapore, Singapore"
            },
            {
                "name": "Daniel Thalmann",
                "org": "Nanyang Technological University,, Singapore, Singapore"
            },
            {
                "name": "Neil Yorke-Smith",
                "org": "American University of Beirut, and University of Cambridge, Beirut, and Cambridge, United Kingdom"
            }
        ],
        "venue": "RecSys",
        "year": 2013
    },
    "aL7Bik27": {
        "id": "aL7Bik27",
        "title": "A framework to choose trust models for different e-marketplace environments",
        "abstract": "Many trust models have been proposed to evaluate seller trustworthiness in multiagent e-marketplaces. Their performance varies highly depending on environments where they are applied. However, it is challenging to choose suitable models for environments where ground truth about seller trustworthiness is unknown (called unknown environments). We propose a novel framework to choose suitable trust models for unknown environments, based on the intuition that if a model performs well in one environment, it will do so in another similar environment. Specifically, for an unknown environment, we identify a similar simulated environment (with known ground truth) where the trust model performing the best will be chosen as the suitable solution. Evaluation results confirm the effectiveness of our framework in choosing suitable trust models for different environments.",
        "keywords": [
            "similar simulated environment",
            "similar environment",
            "suitable model",
            "ground truth",
            "unknown environment",
            "different e-marketplace environment",
            "suitable trust model",
            "suitable solution",
            "different environment",
            "seller trustworthiness",
            "trust model"
        ],
        "authors": [
            {
                "name": "Athirai A. Irissappane",
                "org": "School of Computer Engineering, Nanyang Technological University, Singapore"
            },
            {
                "name": "Siwei Jiang",
                "org": "School of Computer Engineering, Nanyang Technological University, Singapore"
            },
            {
                "name": "Jie Zhang",
                "org": "School of Computer Engineering, Nanyang Technological University, Singapore"
            }
        ],
        "venue": "IJCAI",
        "year": 2013
    },
    "YIgje95Q": {
        "id": "YIgje95Q",
        "title": "A framework for trust modeling in multiagent electronic marketplaces with buying advisors to consider varying seller behavior and the limiting of seller bids",
        "abstract": "In this article, we present a framework of use in electronic marketplaces that allows buying agents to model the trustworthiness of selling agents in an effective way, making use of seller ratings provided by other buying agents known as advisors. The trustworthiness of the advisors is also modeled, using an approach that combines both personal and public knowledge and allows the relative weighting to be adjusted over time. Through a series of experiments that simulate e-marketplaces, including ones where sellers may vary their behavior over time, we are able to demonstrate that our proposed framework delivers effective seller recommendations to buyers, resulting in important buyer profit. We also propose limiting seller bids as a method for promoting seller honesty, thus facilitating successful selection of sellers by buyers, and demonstrate the value of this approach through experimental results. Overall, this research is focused on the technological aspects of electronic commerce and specifically on technology that would be used to manage trust.",
        "keywords": [
            "seller bid",
            "electronic marketplace",
            "seller rating",
            "multiagent electronic marketplace",
            "important buyer profit",
            "effective seller recommendation",
            "trust modeling",
            "varying seller behavior",
            "proposed framework",
            "buying agent",
            "seller honesty",
            "electronic commerce",
            "social networks",
            "multiagent systems"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Nanyang Technological University, Singapore"
            },
            {
                "name": "Robin Cohen",
                "org": "University of Waterloo, Canada"
            }
        ],
        "venue": "ACM TIST",
        "year": 2013
    },
    "TLNgP85f": {
        "id": "TLNgP85f",
        "title": "Improving trust modeling through the limit of advisor network size and use of referrals",
        "abstract": "This paper explores potential improvements to the trust modeling of agents in multi-agent systems when a social network of advisors is employed as part of the trust modeling, and in particular, examines means of optimizing the number of advisors that should be maintained in the social network. We propose three such improvements, two directly relating to the limit of advisor network size by either setting a maximum size for a buyer's advisor network or setting a minimum trustworthiness threshold for agents to be accepted into that advisor network, and a third which uses an advisor referral system in combination with one of the first two network-limiting techniques. We provide experimental results in defence of our approach for two distinct trust modeling systems, and show how these optimizations can improve, sometimes significantly, the accuracy of different trust models (in the context of electronic marketplaces). We believe that the proposed techniques will be very useful for trust researchers seeking to improve the accuracy of their own trust models by setting the size and composition of advisor networks.",
        "keywords": [
            "advisor network size",
            "social network",
            "advisor network",
            "distinct trust modeling system",
            "advisor referral system",
            "improving trust modeling",
            "own trust model",
            "maximum size",
            "different trust model",
            "trust modeling",
            "trust researcher",
            "multi agent systems"
        ],
        "authors": [
            {
                "name": "Joshua Gorner",
                "org": "School of Computer Science, University of Waterloo, Canada"
            },
            {
                "name": "Jie Zhang",
                "org": "School of Computer Engineering, Nanyang Technological University, Singapore"
            },
            {
                "name": "Robin Cohen",
                "org": "School of Computer Science, University of Waterloo, Canada"
            }
        ],
        "venue": "Electronic Commerce Research and Applications",
        "year": 2013
    },
    "0mArd6JJ": {
        "id": "0mArd6JJ",
        "title": "Misleading opinions provided by advisors: dishonesty or subjectivity",
        "abstract": "It is indispensable for users to evaluate the trustworthiness of other users (referred to as advisors), to cope with possible misleading opinions provided by them. Advisors' misleading opinions may be induced by their dishonesty, subjectivity difference with users, or both. Existing approaches do not well distinguish the two different causes. In this paper, we propose a novel probabilistic graphical trust model to separately consider these two factors, involving three types of latent variables: benevolence, integrity and competence of advisors, trust propensity of users, and subjectivity difference between users and advisors. Experimental results on real datasets demonstrate that our method advances state-of-the-art approaches to a large extent.",
        "keywords": [
            "trust propensity",
            "method advances state-of-the-art approach",
            "possible misleading opinion",
            "subjectivity difference",
            "novel probabilistic graphical trust",
            "large extent",
            "latent variable",
            "different cause",
            "misleading opinion"
        ],
        "authors": [
            {
                "name": "Hui Fang",
                "org": "School of Computer Engineering, Nanyang Technological University, Singapore"
            },
            {
                "name": "Yang Bao",
                "org": "School of Computing, National University of Singapore, Singapore"
            },
            {
                "name": "Jie Zhang",
                "org": "School of Computer Engineering, Nanyang Technological University, Singapore"
            }
        ],
        "venue": "IJCAI",
        "year": 2013
    },
    "PMI1xjfG": {
        "id": "PMI1xjfG",
        "title": "An evolutionary model for constructing robust trust networks",
        "abstract": "In reputation systems for multiagent-based e-marketplaces, buying agents model the reputation of selling agents based on ratings shared by other buyers (called advisors). With the existence of unfair rating attacks from dishonest advisors, the effectiveness of reputation systems thus heavily relies on whether buyers can accurately determine which advisors to include in trust networks and their trustworthiness. In this paper, we propose a novel multiagent evolutionary trust model (MET) where each buyer evolves its trust network. In each generation, each buyer acquires trust network information from its advisors and generates a candidate trust network using evolutionary operators. Only trust networks providing more accurate seller reputation estimation shall survive to the next generation. Experimental results demonstrate MET is more robust than the state-of-the-art trust models against various unfair rating attacks.",
        "keywords": [
            "state-of-the-art trust model",
            "reputation system",
            "trust network information",
            "novel multiagent evolutionary trust",
            "accurate seller reputation estimation",
            "trust network",
            "evolutionary operator",
            "candidate trust network",
            "agents model",
            "evolutionary model",
            "robust trust network",
            "next generation"
        ],
        "authors": [
            {
                "name": "Siwei Jiang",
                "org": "School of Computer Engineering, Nanyang Technological University, Singapore, 639798, Singapore, Singapore"
            },
            {
                "name": "Jie Zhang",
                "org": "School of Computer Engineering, Nanyang Technological University, Singapore, 639798, Singapore, Singapore"
            },
            {
                "name": "Yew-Soon Ong",
                "org": "School of Computer Engineering, Nanyang Technological University, Singapore, 639798, Singapore, Singapore"
            }
        ],
        "venue": "AAMAS",
        "year": 2013
    },
    "DRlFNrbt": {
        "id": "DRlFNrbt",
        "title": "Robustness evaluation of incentive mechanisms",
        "abstract": "A general assumption for incentive mechanisms is that all agents are rational and seek to maximize their utility. When some agents are irrational and launch various attacks, these mechanisms may fail to work. To address the issue of evaluating the robustness of incentive mechanisms, we propose a robustness metric in this paper. It is inspired by the studies of the evolutionary game theory and defined as the maximum percentage of irrational agents existing in the system while it is still better off for rational agents to perform desired strategies. Then a simulation framework is designed to measure the robustness of incentive mechanisms, and is verified to be able to produce the same results as those by theoretical analysis. Finally, we demonstrate the usage of our simulation framework in evaluating and comparing the robustness of two incentive mechanisms where irrational agents adopt different attacking strategics.",
        "keywords": [
            "incentive mechanism",
            "simulation framework",
            "irrational agent",
            "general assumption",
            "maximum percentage",
            "rational agent",
            "various attack",
            "different attacking strategics",
            "robustness evaluation",
            "theoretical analysis",
            "evolutionary game theory",
            "mechanism design",
            "robustness"
        ],
        "authors": [
            {
                "name": "Yuan Liu",
                "org": "Nanyang Technological University, Singapore, Singapore"
            },
            {
                "name": "Jie Zhang",
                "org": "Nanyang Technological University, Singapore, Singapore"
            }
        ],
        "venue": "AAMAS",
        "year": 2013
    },
    "4SysDDAe": {
        "id": "4SysDDAe",
        "title": "A trust model stemmed from the diffusion theory for opinion evaluation",
        "abstract": "In open online communities, everyone can freely express opinions about other entities. As the quality of opinions may vary, it is important for users to evaluate opinions in order to determine how much to rely on. In this paper, we propose a novel trust model stemmed from the diffusion theory in social science (called DiffTrust), to evaluate the opinions of users (referred to as advisors) by modeling their trustworthiness. Specifically, an advisor's trust building among users is considered as a diffusion process. Her trustworthiness perceived by a specific user is influenced by four important factors including the advisor's characteristics directly observed by the user, susceptibility of the user, the contagious influence of other users already having a certain level of trust on the advisor and the environment. DiffTrust also emphasizes on the dynamics of trust. Experimental results based on four real datasets verify the effectiveness of our model in comparison with state-of-the-art approaches.",
        "keywords": [
            "open online community",
            "specific user",
            "important factor",
            "novel trust model",
            "contagious influence",
            "diffusion theory",
            "diffusion process",
            "trust building",
            "opinion evaluation",
            "certain level",
            "intelligent agent"
        ],
        "authors": [
            {
                "name": "Hui Fang",
                "org": "Nanyang Technological University, Singapore, Singapore"
            },
            {
                "name": "Jie Zhang",
                "org": "Nanyang Technological University, Singapore, Singapore"
            },
            {
                "name": "Nadia Magnenat Thalmann",
                "org": "Nanyang Technological University, Singapore, Singapore"
            }
        ],
        "venue": "AAMAS",
        "year": 2013
    },
    "PITBmfRc": {
        "id": "PITBmfRc",
        "title": "A Simple and Fast Hypervolume Indicator-Based Multiobjective Evolutionary Algorithm",
        "abstract": "To find diversified solutions converging to true Pareto fronts (PFs), hypervolume (HV) indicator-based algorithms have been established as effective approaches in multiobjective evolutionary algorithms (MOEAs). However, the bottleneck of HV indicator-based MOEAs is the high time complexity for measuring the exact HV contributions of different solutions. To cope with this problem, in this paper, a simple and fast hypervolume indicator-based MOEA (FV-MOEA) is proposed to quickly update the exact HV contributions of different solutions. The core idea of FV-MOEA is that the HV contribution of a solution is only associated with partial solutions rather than the whole solution set. Thus, the time cost of FV-MOEA can be greatly reduced by deleting irrelevant solutions. Experimental studies on 44 benchmark multiobjective optimization problems with 2-5 objectives in platform jMetal demonstrate that FV-MOEA not only reports higher hypervolumes than the five classical MOEAs (nondominated sorting genetic algorithm II (NSGAII), strength Pareto evolutionary algorithm 2 (SPEA2), multiobjective evolutionary algorithm based on decomposition (MOEA/D), indicator-based evolutionary algorithm, and S-metric selection based evolutionary multiobjective optimization algorithm (SMS-EMOA)), but also obtains significant speedup compared to other HV indicator-based MOEAs.",
        "keywords": [
            "multiobjective evolutionary algorithms (moeas)",
            "scalarizing function-based",
            "hypervolume (hv)",
            "indicator-based",
            "jmetal",
            "pareto dominance-based",
            "statistics",
            "time complexity",
            "sociology",
            "vectors",
            "evolutionary computation"
        ],
        "authors": [
            {
                "name": "Jiang Siwei",
                "org": "Singapore Institute of Manufacturing Technology, Singapore 638075.|c|"
            },
            {
                "name": "Zhang Jie",
                "org": ""
            },
            {
                "name": "Ong Yew-Soon",
                "org": ""
            },
            {
                "name": "Allan N. Zhang",
                "org": ""
            },
            {
                "name": "Tan Puay Siew",
                "org": ""
            }
        ],
        "venue": "Cybernetics, IEEE Transactions  ",
        "year": 2014
    },
    "8zWQSMEO": {
        "id": "8zWQSMEO",
        "title": "A biclustering-based approach to filter dishonest advisors in multi-criteria e-marketplaces",
        "abstract": "In this paper, we propose a biclustering-based approach to identify dishonest advisors (who provide misleading opinions about sellers), while evaluating seller trustworthiness on multiple criteria. It considers correlation between advisors' ratings to various criteria and trust transitivity to accurately filter the dishonest advisors. Evaluation results demonstrate the robustness of our approach against various types of unfair rating attacks.",
        "keywords": [
            "multi-criteria e-marketplaces",
            "biclustering-based approach",
            "dishonest advisor",
            "various type",
            "seller trustworthiness",
            "evaluation result",
            "unfair rating attack",
            "trust transitivity",
            "multiple criterion",
            "misleading opinion",
            "various criterion"
        ],
        "authors": [
            {
                "name": "Athirai A. Irissappane",
                "org": "Nanyang Technological University, Singapore, Singapore"
            },
            {
                "name": "Siwei Jiang",
                "org": "Nanyang Technological University, Singapore, Singapore"
            },
            {
                "name": "Jie Zhang",
                "org": "Nanyang Technological University, Singapore, Singapore"
            }
        ],
        "venue": "AAMAS",
        "year": 2014
    },
    "xSlNs8ts": {
        "id": "xSlNs8ts",
        "title": "A practical robustness measure of incentive mechanisms.",
        "abstract": "In this abstract, we propose a general robustness definition for a desired equilibrium and a practical robustness measure against a non-equilibrium strategy, inspired by the studies of evolutionary game theory. We also propose a framework to quantitatively evaluate the robustness and provide theoretical analysis of the framework.",
        "keywords": [
            "practical robustness measure",
            "non-equilibrium strategy",
            "theoretical analysis",
            "evolutionary game theory",
            "general robustness definition",
            "incentive mechanism"
        ],
        "authors": [
            {
                "name": "Yuan Liu",
                "org": "School of Computer Engineering, Nanyang Technological University, Singapore, Singapore"
            },
            {
                "name": "Jie Zhang",
                "org": "School of Computer Engineering, Nanyang Technological University, Singapore, Singapore"
            },
            {
                "name": "Bo An",
                "org": "School of Computer Engineering, Nanyang Technological University, Singapore, Singapore"
            },
            {
                "name": "Sandip Sen",
                "org": "Department of Mathematical and Computer Sciences, The University of Tulsa, USA, USA"
            }
        ],
        "venue": "AAMAS",
        "year": 2014
    },
    "kDdHLAEL": {
        "id": "kDdHLAEL",
        "title": "A testbed to evaluate the robustness of reputation systems in e-marketplaces",
        "abstract": "Existing testbeds to evaluate reputation systems are mainly simulation based and are not flexible to perform robustness evaluations against unfair rating attacks. In this paper, we present a novel comprehensive testbed, which can evaluate reputation systems using both simulations and real data. The testbed incorporates sophisticated deception models and unfair rating attack models, and introduces several performance metrics to fully test and compare the effectiveness and robustness of different reputation systems.",
        "keywords": [
            "reputation system",
            "different reputation system",
            "robustness evaluation",
            "unfair rating attack model",
            "unfair rating attack",
            "sophisticated deception model",
            "performance metrics"
        ],
        "authors": [
            {
                "name": "Athirai A. Irissappane",
                "org": "Nanyang Technological University, Singapore, Singapore"
            },
            {
                "name": "Jie Zhang",
                "org": "Nanyang Technological University, Singapore, Singapore"
            }
        ],
        "venue": "AAMAS",
        "year": 2014
    },
    "t3YZEnFS": {
        "id": "t3YZEnFS",
        "title": "ETAF: An extended trust antecedents framework for trust prediction",
        "abstract": "Trust is one source of information that has been widely adopted to personalize online services for users, such as in product recommendations. However, trust information is usually very sparse or unavailable for most online systems. To narrow this gap, we propose a principled approach that predicts implicit trust from users' interactions, by extending a well-known trust antecedents framework. Specifically, we consider both local and global trustworthiness of target users, and form a personalized trust metric by further taking into account the active user's propensity to trust. Experimental results on two real-world datasets show that our approach works better than contemporary counterparts in terms of trust ranking performance when direct user interactions are limited.",
        "keywords": [
            "etaf",
            "user ratings",
            "trust ranking performance",
            "trust prediction",
            "personalized trust metric",
            "user interactions",
            "product recommendations",
            "user interfaces",
            "global trustworthiness",
            "direct user interactions",
            "trust antecedents framework",
            "extended trust antecedents framework",
            "local trustworthiness",
            "active user propensity",
            "real-world datasets",
            "security of data",
            "computational modeling",
            "measurement",
            "support vector machines"
        ],
        "authors": [
            {
                "name": "Guibing Guo",
                "org": "Nanyang Technological University, Singapore"
            },
            {
                "name": "Jie Zhang",
                "org": "Nanyang Technological University, Singapore"
            },
            {
                "name": "Daniel Thalmann",
                "org": "Nanyang Technological University, Singapore"
            },
            {
                "name": "Neil Yorke-Smith",
                "org": "American University of Beirut, Lebanon and University of Cambridge, UK"
            }
        ],
        "venue": "ASONAM",
        "year": 2014
    },
    "YsWWGVev": {
        "id": "YsWWGVev",
        "title": "From ratings to trust: an empirical study of implicit trust in recommender systems",
        "abstract": "Trust has been extensively studied and its effectiveness demonstrated in recommender systems. Due to the lack of explicit trust information in most systems, many trust metric approaches have been proposed to infer implicit trust from user ratings. However, previous works have not compared these different approaches, and oftentimes focus only on the performance of predictive item ratings. In this paper, we first analyse five kinds of trust metrics in light of the properties of trust. We conduct an empirical study to explore the ability of trust metrics to distinguish explicit trust from implicit trust and to generate accurate predictions. Experimental results on two real-world data sets show that existing trust metrics cannot provide satisfying performance, and indicate that future metrics should be designed more carefully.",
        "keywords": [
            "experimentation",
            "similarity",
            "recommender systems",
            "complexity measures",
            "general",
            "ratings",
            "trust metrics",
            "performance measures"
        ],
        "authors": [
            {
                "name": "Guibing Guo",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Daniel Thalmann",
                "org": ""
            },
            {
                "name": "Anirban Basu",
                "org": ""
            },
            {
                "name": "Neil Yorke-Smith",
                "org": ""
            }
        ],
        "venue": "SAC",
        "year": 2014
    },
    "Q0QIwJ08": {
        "id": "Q0QIwJ08",
        "title": "Consistencies and contradictions of performance metrics in multiobjective optimization.",
        "abstract": "An important consideration of multiobjective optimization (MOO) is the quantitative metrics used for defining the optimality of different solution sets, which is also the basic principle for the design and evaluation of MOO algorithms. Although a plethora of performance metrics have been proposed in the MOO context, there has been a lack of insights on the relationships between metrics. In this paper, we first group the major MOO metrics proposed to date according to four core performance criteria considered in the literature, namely, capacity, convergence, diversity, and convergence-diversity. Then, a comprehensive study is conducted to investigate the relationships among representative group metrics, including generational distance, ϵ-indicator (I(1)ϵ+), spread (∆), generalized spread (∆∗), inverted generational distance, and hypervolume. Experimental results indicated that these six metrics show high consistencies when Pareto fronts (PFs) are convex, whereas they show certain contradictions on concave PFs.",
        "keywords": [],
        "authors": [
            {
                "name": "Siwei Jiang",
                "org": "Sch. of Comput. Eng., Nanyang Technol. Univ., Singapore, Singapore|c|"
            },
            {
                "name": "Yew-Soon Ong",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Liang Feng",
                "org": ""
            }
        ],
        "venue": "IEEE T. Cybernetics",
        "year": 2014
    },
    "IZQBhFNd": {
        "id": "IZQBhFNd",
        "title": "Merging trust in collaborative filtering to alleviate data sparsity and cold start",
        "abstract": "Providing high quality recommendations is important for e-commerce systems to assist users in making effective selection decisions from a plethora of choices. Collaborative filtering is a widely accepted technique to generate recommendations based on the ratings of like-minded users. However, it suffers from several inherent issues such as data sparsity and cold start. To address these problems, we propose a novel method called ''Merge'' to incorporate social trust information (i.e., trusted neighbors explicitly specified by users) in providing recommendations. Specifically, ratings of a user's trusted neighbors are merged to complement and represent the preferences of the user and to find other users with similar preferences (i.e., similar users). In addition, the quality of merged ratings is measured by the confidence considering the number of ratings and the ratio of conflicts between positive and negative opinions. Further, the rating confidence is incorporated into the computation of user similarity. The prediction for a given item is generated by aggregating the ratings of similar users. Experimental results based on three real-world data sets demonstrate that our method outperforms other counterparts both in terms of accuracy and coverage.",
        "keywords": [
            "merging trust",
            "novel method",
            "like-minded user",
            "cold start",
            "merged rating",
            "user similarity",
            "similar preference",
            "data sparsity",
            "real-world data set",
            "high quality recommendation",
            "similar user",
            "rating confidence",
            "recommender systems",
            "collaborative filtering"
        ],
        "authors": [
            {
                "name": "Guibing Guo",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Daniel Thalmann",
                "org": ""
            }
        ],
        "venue": "Knowl.-Based Syst.",
        "year": 2014
    },
    "0ie7nTFV": {
        "id": "0ie7nTFV",
        "title": "A SUPER-AGENT-BASED FRAMEWORK FOR REPUTATION MANAGEMENT AND COMMUNITY FORMATION IN DECENTRALIZED SYSTEMS: A SUPER-AGENT FRAMEWORK FOR DECENTRALIZED SYSTEMS",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "julita vassileva",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "yao wang",
                "org": ""
            }
        ],
        "venue": "computational intelligence",
        "year": 2014
    },
    "qnSBvd38": {
        "id": "qnSBvd38",
        "title": "SocialTrust: Adaptive Trust Oriented Incentive Mechanism for Social Commerce",
        "abstract": "In the absence of legal authorities and enforcement mechanisms in open e-marketplaces, it is extremely challenging for a user to validate the quality of opinions (i.e. Ratings and reviews) of products or services provided by other users (referred as advisers). Rationally, advisers tend to be reluctant to share their truthful experience with others. In this paper, we propose an adaptive incentive mechanism, where advisers are motivated to share their actual experiences with their trustworthy peers (friends/neighbors in the social network) in e-marketplaces (social commerce context), and malicious users will be eventually evacuated from the systems. Experimental results demonstrate the effectiveness of our mechanism in promoting the honesty of users in sharing their past experiences.",
        "keywords": [
            "trust, reputation systems, electronic commerce, incentive mechanism",
            "electronic commerce",
            "trust",
            "quality of service",
            "measurement",
            "servers",
            "business"
        ],
        "authors": [
            {
                "name": "Zeinab Noorian",
                "org": ""
            },
            {
                "name": "Mohsen Mohkami",
                "org": ""
            },
            {
                "name": "Yuan Liu",
                "org": ""
            },
            {
                "name": "Hui Fang",
                "org": ""
            },
            {
                "name": "Julita Vassileva",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            }
        ],
        "venue": "WI-IAT",
        "year": 2014
    },
    "cHerWwI6": {
        "id": "cHerWwI6",
        "title": "Leveraging prior ratings for recommender systems in e-commerce.",
        "abstract": "",
        "keywords": [
            "recommender systems",
            "cold start"
        ],
        "authors": [
            {
                "name": "Guibing Guo",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Daniel Thalmann",
                "org": ""
            },
            {
                "name": "Neil Yorke-Smith",
                "org": ""
            }
        ],
        "venue": "Electronic Commerce Research and Applications",
        "year": 2014
    },
    "eECLM5fC": {
        "id": "eECLM5fC",
        "title": "A Biclustering-Based Approach to Filter Dishonest Advisors in Multi-Criteria E-Marketplaces (Extended Abstract)",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "athirai a irissappane",
                "org": ""
            },
            {
                "name": "siwei jiang",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2014
    },
    "KpCYIyjX": {
        "id": "KpCYIyjX",
        "title": "An incentive mechanism designed for e-marketplaces with limited inventory.",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Yuan Liu",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            }
        ],
        "venue": "Electronic Commerce Research and Applications",
        "year": 2014
    },
    "msxWBHgf": {
        "id": "msxWBHgf",
        "title": "A trust-based framework for vehicular travel with non-binary reports and its validation via an extensive simulation testbed",
        "abstract": "In this paper, we offer an algorithm for intelligent decision making about travel path planning in mobile vehicular ad-hoc networks (VANETs), for scenarios where agents representing vehicles exchange reports about traffic. One challenge that arises is how best to model the trustworthiness of those traffic reports. To this end, we outline an algorithm for effectively soliciting, receiving and analyzing the trustworthiness of these reports, to drive a vehicle’s decision about the path to follow. Distinct from earlier work, we clarify the need for specifying the conditions under which reports are exchanged and for processing non-binary reports, culminating in a proposed algorithm to achieve that processing, as part of the trust modeling and path planning. To validate our approach we then offer a detailed evaluation framework that achieves large scale simulation of traffic, travel and reporting of information, confirming the value of our proposed approach by demonstrating the average speed of vehicles which follow our algorithm (compared to ones that do not). This experimental framework is promoted as a significant contribution towards the goal of evaluating trust algorithms for intelligent decision making in traffic scenarios.",
        "keywords": [
            "Multi-faceted trust modeling",
            " Multiagent systems",
            " VANET",
            " Vehicle routing",
            " Traffic control"
        ],
        "authors": [
            {
                "name": "robin cohen",
                "org": "david r cheriton school of computer science"
            },
            {
                "name": "jie zhang",
                "org": "nanyang technological university"
            },
            {
                "name": "john finnson",
                "org": "david r cheriton school of computer science"
            },
            {
                "name": "thomas tran",
                "org": "university of ottawa"
            },
            {
                "name": "umar farooq minhas",
                "org": "david r cheriton school of computer science"
            }
        ],
        "venue": "",
        "year": 2014
    },
    "YFZ0Z7mX": {
        "id": "YFZ0Z7mX",
        "title": "A POMDP based approach to optimally select sellers in electronic marketplaces",
        "abstract": "Selecting a seller in e-markets is a tedious task that we might want to delegate to an agent. Many approaches to constructing such agents have been proposed, building upon different foundations (decision theory, trust modeling) and making use of different information (direct experience with sellers, reputation of sellers, trustworthiness of other buyers called advisors, etc.). In this paper, we propose the SALE POMDP, a new approach based on the decision-theoretic framework of POMDPs. It enables optimal trade-offs of information gaining and exploiting actions, with the ultimate goal of maximizing buyer satisfaction. A unique feature of the model is that it allows querying advisors about the trustworthiness of other advisors. We represent the model as a factored POMDP, thereby enabling the use of computationally more efficient solution methods. Evaluation on the ART testbed demonstrates that SALE POMDP balances the cost of obtaining and benefit of more information more effectively, leading to more earnings, than traditional trust models. Experiments also show that it is more robust to deceptive advisors than a previous POMDP based approach, and that the factored formulation allows the solution of reasonably large instances of seller selection problems.",
        "keywords": [
            "factored pomdp",
            "efficient solution method",
            "select seller",
            "previous pomdp",
            "seller selection problem",
            "factored formulation",
            "electronic marketplace",
            "different foundation",
            "sale pomdp",
            "different information",
            "traditional trust model",
            "new approach"
        ],
        "authors": [
            {
                "name": "Athirai A. Irissappane",
                "org": "Nanyang Technological University, Singapore, Singapore"
            },
            {
                "name": "Frans A. Oliehoek",
                "org": "University of Amsterdam & Maastricht University, Amsterdam, Netherlands"
            },
            {
                "name": "Jie Zhang",
                "org": "Nanyang Technological University, Singapore, Singapore"
            }
        ],
        "venue": "AAMAS",
        "year": 2014
    },
    "AbLD1hPJ": {
        "id": "AbLD1hPJ",
        "title": "Subjectivity grouping: learning from users' rating behavior",
        "abstract": "Considering opinions of other users (called advisors) has become increasingly important for each user in open and dynamic online environments. However, users might be subjectively different or strategically dishonest. Previous approaches on this problem generally suffer from the issue of limited (especially shared) historic experience when tracking each individual advisor's behavior. In this paper, instead, we model each advisor as part of groups by proposing a two-layered clustering approach. Specifically, in the first layer, the agent of each user clusters her advisors into different subjectivity groups and dishonest types, with respect to their rating behavior. In the second layer, each advisor is assigned to groups with respective membership degrees. Finally, each agent adopts an alignment approach to help its user align advisors' ratings to the ones of her own. Experimental results on both simulations and real data verify that our approach can better help users utilize ratings provided by advisors in opinion evaluation and recommender systems.",
        "keywords": [
            "different subjectivity group",
            "dynamic online environment",
            "two-layered clustering approach",
            "rating behavior",
            "alignment approach",
            "dishonest type",
            "previous approach",
            "individual advisor",
            "user cluster",
            "user align advisor",
            "subjectivity grouping"
        ],
        "authors": [
            {
                "name": "Hui Fang",
                "org": "Nanyang Technological University, Singapore, Singapore"
            },
            {
                "name": "Jie Zhang",
                "org": "Nanyang Technological University, Singapore, Singapore"
            },
            {
                "name": "Nadia Magnenat Thalmann",
                "org": "Nanyang Technological University, Singapore, Singapore"
            }
        ],
        "venue": "AAMAS",
        "year": 2014
    },
    "NTKztWKR": {
        "id": "NTKztWKR",
        "title": "An extensive model checking framework for multi-agent systems",
        "abstract": "In this work, we propose a novel probabilistic modeling language PML-MAS to capture the stochastic characteristics of multi-agent systems (MASs). Moreover, we design a model checking framework for MAS, which is highly extensible. It provides powerful modeling editor, interactive simulator and automatic verifier for MASs. In addition, it can support various MAS model languages via extracting their semantic models and verification algorithms.",
        "keywords": [
            "semantic model",
            "automatic verifier",
            "interactive simulator",
            "model checking framework",
            "stochastic characteristic",
            "multi-agent system",
            "verification algorithm",
            "powerful modeling editor",
            "various mas model language",
            "extensive model checking framework",
            "novel probabilistic modeling language"
        ],
        "authors": [
            {
                "name": "Songzheng Song",
                "org": "Nanyang Technological University, Singapore, Singapore"
            },
            {
                "name": "Yang Liu",
                "org": "Nanyang Technological University, Singapore, Singapore"
            },
            {
                "name": "Jie Zhang",
                "org": "Nanyang Technological University, Singapore, Singapore"
            },
            {
                "name": "Jun Sun",
                "org": "Singapore University of Technology and Design, Singapore, Singapore"
            }
        ],
        "venue": "AAMAS",
        "year": 2014
    },
    "5CQOc5vy": {
        "id": "5CQOc5vy",
        "title": "Leveraging Decomposed Trust in Probabilistic Matrix Factorization for Effective Recommendation.",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Hui Fang",
                "org": "nanyang technological university"
            },
            {
                "name": "Yang Bao",
                "org": "nanyang technological university"
            },
            {
                "name": "Jie Zhang",
                "org": "nanyang technological university"
            }
        ],
        "venue": "AAAI",
        "year": 2014
    },
    "gsAoowzD": {
        "id": "gsAoowzD",
        "title": "TopicMF: Simultaneously Exploiting Ratings and Reviews for Recommendation.",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Yang Bao",
                "org": "nanyang technological university"
            },
            {
                "name": "Hui Fang",
                "org": "nanyang technological university"
            },
            {
                "name": "Jie Zhang",
                "org": "nanyang technological university"
            }
        ],
        "venue": "AAAI",
        "year": 2014
    },
    "aY8nLHgp": {
        "id": "aY8nLHgp",
        "title": "RepRev: Mitigating the Negative Effects of Misreported Ratings.",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Yuan Liu",
                "org": "nanyang technological university"
            },
            {
                "name": "Siyuan Liu",
                "org": "nanyang technological university"
            },
            {
                "name": "Jie Zhang",
                "org": "nanyang technological university"
            },
            {
                "name": "Hui Fang",
                "org": "nanyang technological university"
            },
            {
                "name": "Han Yu",
                "org": "nanyang technological university"
            },
            {
                "name": "Chunyan Miao",
                "org": "nanyang technological university"
            }
        ],
        "venue": "AAAI",
        "year": 2014
    },
    "hCM9T5ow": {
        "id": "hCM9T5ow",
        "title": "A pheromone-based traffic management model for vehicle re-routing and traffic light control.",
        "abstract": "We propose a pheromone-based traffic management model, which simultaneously optimizes vehicle re-routing and traffic light control. Specifically, each car agent deposits multiple digital pheromone on its route. The road infrastructure agents fuse the pheromone to forecast traffic conditions. Once a congested road is predicted, we adopt a proactive vehicle re-routing algorithm for assigning alternative routes to cars before they enter the congested road. At the same time, the traffic light control agents use an online strategy for assigning long time duration of green traffic lights to the roads with a large amount of pheromone. Experimental results confirm its superiority in alleviating traffic congestion.",
        "keywords": [
            "traffic congestion",
            "long time duration",
            "vehicle re-routing",
            "pheromone-based traffic management model",
            "multiple digital pheromone",
            "traffic condition",
            "road infrastructure agents fuse",
            "traffic light control agent",
            "congested road",
            "green traffic light",
            "traffic light control"
        ],
        "authors": [
            {
                "name": "Siwei Jiang",
                "org": "Nanyang Technological University, Singapore, 639798, Singapore, Singapore"
            },
            {
                "name": "Jie Zhang",
                "org": "Nanyang Technological University, Singapore, 639798, singapore, Singapore"
            },
            {
                "name": "Yew-Soon Ong",
                "org": "Nanyang Technological University, Singapore, 639798, Singapore, Singapore"
            }
        ],
        "venue": "AAMAS",
        "year": 2014
    },
    "4jeYdRI4": {
        "id": "4jeYdRI4",
        "title": "An Agent-based Simulation System for Dynamic Project Scheduling and Online Disruption Resolving",
        "abstract": "This work proposes an agent-based simulation system to address challenges in resource constrained multi project scheduling for a technology intensive industrial product development programme. The system aims at helping users develop robust programme schedules by taking care of intra- and inter- dependencies between projects, potential knock-on effect of unpredictable events, and resource constraints. With the interactive graphic user interface embedded in the system, users are enabled to investigate project process, evaluate modified programme schedule and conduct various what-if analysis.",
        "keywords": [],
        "authors": [
            {
                "name": "Hui Xi",
                "org": "RollsRoyce Singapore Pte Ltd, Singapore, Singapore"
            },
            {
                "name": "Chi Keong Goh",
                "org": "RollsRoyce Singapore Pte Ltd, Singapore, Singapore"
            },
            {
                "name": "Partha Sarathi Dutta",
                "org": "RollsRoyce Singapore Pte Ltd, Singapore, Singapore"
            },
            {
                "name": "Meng Sha",
                "org": "Nanyang Technological University, Singapore, Singapore"
            },
            {
                "name": "Jie Zhang",
                "org": "Nanyang Technological University, Singapore, Singapore"
            }
        ],
        "venue": "Autonomous Agents and Multi-Agent Systems",
        "year": 2015
    },
    "srZ4MTi0": {
        "id": "srZ4MTi0",
        "title": "Automated Agent Behavior Construction for Protocol-Based Multiagent Systems.",
        "abstract": "In this paper we study automated construction of an agent's behavior for a protocol-based multiagent system, where the exact behaviors of the other agents are unknown. This uncertainty makes it challenging to develop an optimal agent behavior that complies with the system protocol, while ensuring achievement of the agent's temporal goals. To solve this problem, we develop an automated method that uses graph search and model checking techniques to construct the optimal agent behavior with respect to a labeled transition systems model of a protocol and linear temporal logic specification of the agent's goals. We show that our algorithm is sound, complete and optimal. We also conducted computational experiments to evaluate the scalability of our method.",
        "keywords": [],
        "authors": [
            {
                "name": "Akin Günay",
                "org": ""
            },
            {
                "name": "Yang Liu",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Partha Sarathi Dutta",
                "org": ""
            }
        ],
        "venue": "WI-IAT",
        "year": 2015
    },
    "hyJyYvLP": {
        "id": "hyJyYvLP",
        "title": "An Agent-based Simulation System for Dynamic Project Scheduling and Online Disruption Resolving (Extended Abstract)",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "hui xi",
                "org": ""
            },
            {
                "name": "chi keong goh",
                "org": ""
            },
            {
                "name": "sarathi dutta",
                "org": ""
            },
            {
                "name": "meng sha",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2015
    },
    "SdAvEHME": {
        "id": "SdAvEHME",
        "title": "LibRec: A Java Library for Recommender Systems.",
        "abstract": "The large array of recommendation algorithms proposed over the years brings a challenge in reproducing and comparing their performance. This paper introduces an open-source Java library that implements a suite of state-of-the-art algorithms as well as a series of evaluation metrics. We empirically find that LibRec performs faster than other such libraries, while achieving competitive evaluative performance.",
        "keywords": [],
        "authors": [
            {
                "name": "Guibing Guo",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Zhu Sun",
                "org": ""
            },
            {
                "name": "Neil Yorke-Smith",
                "org": ""
            }
        ],
        "venue": "UMAP Workshops",
        "year": 2015
    },
    "8X6D2jXx": {
        "id": "8X6D2jXx",
        "title": "The Fallacy of Endogenous Discounting of Trust Recommendations",
        "abstract": "Recommendations are widely used in recommender systems, reputation systems, and trust-based security systems. Some existing reputation systems and trust-based security systems use the flawed notion of endogenous discounting. Endogenous discounting is the idea that claims deviating from prior expectations should be ignored or discounted, which introduces confirmation bias. To show the fallacy of endogenous discounting, we construct a semantic meta-model that captures the key notions surrounding recommendations. We prove that any model covered by the meta-model can be formulated in a divide-and-conquer fashion. We show how divide-and-conquer clashes with endogenous discounting. Lastly, we discuss the implications on existing work that applies endogenous discounting, and provide suggestions for future work.",
        "keywords": [],
        "authors": [
            {
                "name": "Tim Muller",
                "org": "Nanyang Technological University, Singapore, Singapore"
            },
            {
                "name": "Yang Liu",
                "org": "Nanyang Technological University, Singapore, Singapore"
            },
            {
                "name": "Jie Zhang",
                "org": "Nanyang Technological University, Singapore, Singapore"
            }
        ],
        "venue": "Autonomous Agents and Multi-Agent Systems",
        "year": 2015
    },
    "DTlVuV99": {
        "id": "DTlVuV99",
        "title": "Optical characteristics analysis and simulation of grating light valve",
        "abstract": "The grating light valve (GLV), and optical modulator based on microelectromechanical systems (MEMS), with the changeable components mobile ribbons on its surface, can serve as a diffractive grating, and be used in projection and display fields. The optical performance of GLV is analyzed in details and simulated with interference and diffraction theory. All these indicate that when the GLV is in on state, the mobile ribbons should drop a quarter of the incident wavelength. When the reflectivity of the air gap is different, the effect of the duty ratio on the optical properties is different. The best matching value of duty ratio and reflectivity is presented.",
        "keywords": [
            "Diffraction and gratings",
            "Grating light valve",
            "Microelectromechanical systems"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            },
            {
                "name": "Shanglian Huang",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            },
            {
                "name": "Hongqiao Fu",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            },
            {
                "name": "Xu Yan",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            },
            {
                "name": "Weimin Chen",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            }
        ],
        "venue": "Guangxue Xuebao/Acta Optica Sinica",
        "year": 2005
    },
    "0XbGJpEY": {
        "id": "0XbGJpEY",
        "title": "Study on the magnetic excitation circuit for measuring the cable tension based on magneto-elastic effect in steel cable",
        "abstract": "The principle of cable tension measurement based on magneto-elastic effect for steel cable is introduced. The magnetic circuit structure with double excitation and double circle is put forward. According to the theory of magnetic conductance, the magnetic circuit is theoretically analyzed, and the selection of magnetization mode and magnetic intensity is discussed in details. The structure design of the magnetic circuit was carried out. With the magnetization mode of pulse direct current and the magnetic intensity corresponding to the maximum permeability of the cable, experiments were processed. Experimental results indicate that the structure design of the magnetic circuit is reasonable and reliable. The repeat measurement accuracy is better than 0.5%.",
        "keywords": [
            "Cable tension",
            "Magnetic circuit",
            "Magneto-elastic effect",
            "Permeability"
        ],
        "authors": [
            {
                "name": "Dedong Tang",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            },
            {
                "name": "Shanglian Huang",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            },
            {
                "name": "Weimin Chen",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            }
        ],
        "venue": "Yi Qi Yi Biao Xue Bao/Chinese Journal of Scientific Instrument",
        "year": 2006
    },
    "3pHOhMW0": {
        "id": "3pHOhMW0",
        "title": "Geometrical parameters measurement of contact lens with a novel imaging method",
        "abstract": "An imaging method to measure the geometrical parameters of contact lens is put forward. In imaging method, contact lens is projected into an enlarged image with a projecting lens. An imaging sensor is used to acquire the enlarged image, and a single board computer is adopted to process the image and to do the calculation of parameters. In addition, a glass ring emerged in the liquid was introduced to hold contact lens without any distortion or dehydration. An example of system is provided. With the system, the thickness t can be measured directly, and fore radius r_1 and retral radius r_2 can be calculated with the help of h_1 and h_2 and d_1 and d_2.With an imaging system of 20 times magnification, and a 512 pixels CCD linear imaging sensor of a 50 μm pixel spacing,the system has a resolution of 5 μm, which is much higher than the accuracy requirement of measurement 0.01millimeter.",
        "keywords": [
            "Contact lens",
            "Geometrical parameter",
            "Imaging"
        ],
        "authors": [
            {
                "name": "Weimin Chen",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            }
        ],
        "venue": "Guangzi Xuebao/Acta Photonica Sinica",
        "year": 2006
    },
    "5jfaKjzf": {
        "id": "5jfaKjzf",
        "title": "Optimization and analysis for structural parameters of grating moving light modulator",
        "abstract": "The proposed grating moving light modulator is based on micro-electromechanical system, the diffraction grating is provided by the deformed part on its surface, movable grating, and the two working states, on and off, are realized by controlling the displacement of movable grating. Detailed theoretical analysis and simulation for the optical properties of grating moving light modulator at working state are carried out, and the effects of duty ratio, length, frame length perpendicular to the grating period direction, grating stake width and period number of the movable grating on the working performance of grating moving light modulator are discussed with emphasis. The result shows that, the modulator is off when the distance between the movable grating and the mirror is half of the wavelength of incident light, and when the above distance is shortened to a quarter of the wavelength, the modulator is on. For the optimal contrast, it requires that, the stake width is half of the grating period and the length of the movable grating is integral times of the grating period. When the latter condition is not fulfilled, a high contrast can be obtained with short frame, narrow stake and large period number.",
        "keywords": [
            "Diffraction",
            "Fourier optics",
            "Grating",
            "Light modulator",
            "Micro electro mechanical system"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            },
            {
                "name": "Shanglian Huang",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            },
            {
                "name": "Xu Yan",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            },
            {
                "name": "Weimin Chen",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            },
            {
                "name": "Zhihai Zhang",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            },
            {
                "name": "Hongqiao Fu",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            }
        ],
        "venue": "Guangxue Xuebao/Acta Optica Sinica",
        "year": 2006
    },
    "plMU23HR": {
        "id": "plMU23HR",
        "title": "A Wavelength Scanning Method for Measuring Micro Distance of Grating Moving Light Modulator",
        "abstract": "Grating moving light modulator (GMLM) is a novel MEMS-based movable diffraction grating, which light modulation is completed by changing micro distance between the upper surface of the movable grating and the reflecting surface of the underlying fixed reflector. The micro distance is a key factor to GMLM performance and it is difficult and expensive to measure with a common approach. A novel method adopting wavelength scanning is put forward and analyzed. Multi-peak method is developed to improve measurement accuracy by k multiple. Experiments with U-4100 spectrophotometer are carried on, which indicates that such method is available and experiment results are approaching theory analysis. Comparing with the result measured by WYKO white light interferometer, the error of demodulated result is about 1%. More important, because of wavelength accounted to calculate micro distance, measurement accuracy is up to nanometer level.",
        "keywords": [
            "peak wavelength",
            "grating",
            "grating moving light modulator",
            "wavelength scanning",
            "diffraction"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "the Key Laboratory of Optoelectronic Technology and Systems of the Education Ministry, Chongqing University, Chongqing ,China"
            },
            {
                "name": "HUANG Shang-lian",
                "org": "the Key Laboratory of Optoelectronic Technology and Systems of the Education Ministry, Chongqing University, Chongqing ,China"
            },
            {
                "name": "ZHANG Zhi-hai",
                "org": "the Key Laboratory of Optoelectronic Technology and Systems of the Education Ministry, Chongqing University, Chongqing ,China"
            },
            {
                "name": "SUN Ji-yong",
                "org": "the Key Laboratory of Optoelectronic Technology and Systems of the Education Ministry, Chongqing University, Chongqing ,China"
            }
        ],
        "venue": "Chinese Journal of Sensors and Actuators",
        "year": 2006
    },
    "G704cYbw": {
        "id": "G704cYbw",
        "title": "Optical characteristic analysis of grating moving light modulator",
        "abstract": "This paper presents a novel grating moving light modulator based on Micro Optical Electromechanical System(MOEMS) technology and introduces its structure,operation principle and fabrication process.The device can be used in projection display etc.The relationship between optical characteristics and geometrical parameters of this device is established through optical analysis,optimization and simulation,and the ±1~(st) order diffraction efficiency η and contrast V are theoretically 37.0% and 625 respectively for e=0.5,d=6 μm,L=39 μm,w=36 μm,w_0=1.5 μm and e,d,L,w and w_0 are occupation ratio,grating constant,length,width and margin of the movable grating respectively,the gap between the movable grating and the underlying reflector are 0.65 μm and 0.78 μm respectively in on and off states,and the single pixel size of the device is 51 μm×51 μm.",
        "keywords": [
            "grating diffraction",
            "optical analysis",
            "spatial light modulator",
            "simulation",
            "Micro Optical Electromechanical System(MOMES)"
        ],
        "authors": [
            {
                "name": "HUANG Shang-lian",
                "org": "Key Laboratory of Optoelectronic Technology and System of Ministry of Education,Chongqing University,Chongqing ,China"
            },
            {
                "name": "YAN Xu",
                "org": "Key Laboratory of Optoelectronic Technology and System of Ministry of Education,Chongqing University,Chongqing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Key Laboratory of Optoelectronic Technology and System of Ministry of Education,Chongqing University,Chongqing ,China"
            },
            {
                "name": "ZHANG Zhi-hai",
                "org": "Key Laboratory of Optoelectronic Technology and System of Ministry of Education,Chongqing University,Chongqing ,China"
            },
            {
                "name": "FU Hong-qiao",
                "org": "Key Laboratory of Optoelectronic Technology and System of Ministry of Education,Chongqing University,Chongqing ,China"
            }
        ],
        "venue": "Optics and Precision Engineering",
        "year": 2006
    },
    "xSpmNFCt": {
        "id": "xSpmNFCt",
        "title": "Optical performance analysis and simulation of reflector moving grating light modulator",
        "abstract": "A novel spatial light modulator called reflector moving grating light modulator is proposed. Each pixel mostly consists of a fixed grating and a movable reflector. The optical performance of this modulator is a key parameter, so it is necessary to analyze the optical performance. With scalar diffraction theory, its optical performance is analyzed in details. Meanwhile, computer simulation is carried on, and the influence of several key parameters on the diffraction efficiency and contrast ratio is presented. All these results indicate that the height between the fixed grating and movable reflector must be controlled at λ0 in off state, 5 λ0/4 in on state respectively, and the occupation ratio of the fixed grating has an important influence on the optical performance whose optimized value is 0.5. The contrast ratio at different wavelength width is given out, wider wavelength, worse contrast ratio.",
        "keywords": [
            "Contrast ratio",
            "Diffraction and Grating\\Light modulator",
            "Diffraction efficiency"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            },
            {
                "name": "Shanglian Huang",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            },
            {
                "name": "Xu Yan",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            },
            {
                "name": "Yi Wu",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            },
            {
                "name": "Zhihai Zhang",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            }
        ],
        "venue": "Guangzi Xuebao/Acta Photonica Sinica",
        "year": 2006
    },
    "nPkzXVzL": {
        "id": "nPkzXVzL",
        "title": "Electromechanical characteristics analysis and simulation of grating light modulator",
        "abstract": "In this paper, a 27um×27um novel grating light modulator supported by cantilevers has been presented, and it can be fabricated using silicon surface-micromachining technology. The structure and basic operation principle of grating light modulator is introduced. The structure is composed of grating plate, address electrode and four cantilevers, the grating plate, which is supported by four cantilevers placed around, is overhung about one wavelength of incidence light from the underlying address electrode, it is actuated like a piston by electrostatic force, and piston-type motion of grating can be used to modulate phase of incident light., therefore, the grating light modulator array is a potential device for projection displays and relevant devices for its intrinsic characteristics. Mechanics model is developed for deducing the deformation equation, the relationship between the electromechanical characteristics of the device and the geometrical parameters and material performance is analyzed, such as pull-in voltage, resonance frequency and step response time. Electromechanical coupled simulation is done by Coventorware, then, more reasonable geometrical parameters are obtained for fabricated in the next step.",
        "keywords": [
            "electromechanical characteristics",
            "grating light modulator",
            "moems",
            "projection display device",
            "mechanics",
            "silicon",
            "surface micromachining",
            "displays",
            "resonant frequency",
            "electrodes",
            "electrostatic force"
        ],
        "authors": [
            {
                "name": "Yan Xu",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            },
            {
                "name": "Huang Shanglian",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            },
            {
                "name": "Zhang Jie",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            },
            {
                "name": "Zhang Zhihai",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            }
        ],
        "venue": "Proceedings of SPIE - The International Society for Optical Engineering",
        "year": 2006
    },
    "jAvbPdGM": {
        "id": "jAvbPdGM",
        "title": "The Influence of Support Structure Pattern to the Flatness of Reflector Moving Grating Light Modulator",
        "abstract": "To improve the operating efficiency, a novel optical light modulator, called reflector moving grating light modulator (RMGLM), is presented. It consists of a fixed grating plate, address electrode, support structure, and a movable reflector, piston-type motion of the reflector can be used to modulate the phase of incident light. The RMGLM optical performance is theoretically analyzed with Fourier optics. The flatness of movable reflector which is influenced by support structure pattern, is extraordinary important. To gain optimized flatness, several support structure patterns are presented and compared. The mechanic models of all structures are analyzed. Meanwhile, simulations of the movable reflector surface shape using CoventorWare are carried on. The influence of different parameter for each support structure pattern model is given by data and figures. With optimal characteristic dimension based on homologous aerofoil configuration support structure pattern, the flatness can be higher than 98%, which is available for RMGLM operation",
        "keywords": [
            "Fourier transform optics",
            "diffraction gratings",
            "micro-optomechanical devices",
            "optical modulation",
            "phase modulation",
            "CoventorWare",
            "Fourier optics",
            "address electrode",
            "aerofoil",
            "flatness",
            "reflector moving grating light modulator",
            "support structure pattern"
        ],
        "authors": [
            {
                "name": "Zhang jie",
                "org": "Key Lab. of Optoelectron. Technol. & Syst., Chongqing Univ.|c|"
            },
            {
                "name": "Huang Shanglian",
                "org": ""
            },
            {
                "name": "Yan xu",
                "org": ""
            },
            {
                "name": "Han lei",
                "org": ""
            }
        ],
        "venue": "Zhuhai",
        "year": 2006
    },
    "iOQj6mwp": {
        "id": "iOQj6mwp",
        "title": "Experiments and structural optimization of micro-electro-mechanical system-based grating moving light modulator",
        "abstract": "The experimental research for micro-electro-mechanical system (MEMS)-based grating moving light modulator (GMLM) is important for its further applications. Interference optical signal processing system with GMLM module was carried on, with He-Ne laser as light source, filter placed on the frequency spectrum plane, and microscope and CCD placed on the imaging plane and used for magnifying and recording imaging. The laser beam from He-Ne laser was incident on the GMLM as parallel light after passing a beam expander and a collimating lens, the GMLM is placed on the input plane of the interference optical signal processing system and the result is consistent to theoretical result. The optimization of GMLM model was achieved, the grating frame and cantilevers are processed as non-reflective, and as a result the total reflective surface composed of the movable grating and the nether mirror is integer multiple of grating period. The optimized model was theoretically analyzed in details by scalar diffraction theory, with optical efficiency of 81.06%, filling factor of 74.67% and contrast ratio higher than 5000:1 in the condition of grating period of 8μm, duty ratio of 0.5, grating frame of 2μm, and period number of 6.",
        "keywords": [
            "Coherent optical information processing",
            "Grating",
            "Information optics",
            "Light modulator"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            },
            {
                "name": "Shanglian Huang",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            },
            {
                "name": "Zhihai Zhang",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            },
            {
                "name": "Jiyong Sun",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            },
            {
                "name": "Lingna Shi",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            },
            {
                "name": "Yong Zhu",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            }
        ],
        "venue": "Guangxue Xuebao/Acta Optica Sinica",
        "year": 2007
    },
    "hgsnJuWl": {
        "id": "hgsnJuWl",
        "title": "Signal Processing Analysis of Grating Moving Light Modulator Based on MEMS",
        "abstract": "Fourier optics is adopted to analyze the distribution in the imaging plane,using two different filters in frequency spectrum plane.The analysis indicates that collecting 1st order spectrum can get even dark field,but uneven bright field according to the influence of frame and crab-cantilevers,and collecting 0th order spectrum can not only get uneven dark field,but also uneven bright field.In order to get higher even brightness field in imaging field, grating period should be double grating width and reduce the frame and crab-cantilevers size.",
        "keywords": [
            "Diffraction",
            "Fourier optics",
            "Grating",
            "Grating moving light modulator",
            "Signal processing"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "The Key Laboratory of Optoelectronic Technology and Systems of the Education Ministry,Chongqing University,Chongqing ,China"
            },
            {
                "name": "Shanglian Huang",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            },
            {
                "name": "ZHANG Zhi-hai",
                "org": "The Key Laboratory of Optoelectronic Technology and Systems of the Education Ministry,Chongqing University,Chongqing ,China"
            },
            {
                "name": "Jiyong Sun",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            },
            {
                "name": "SHI Ling-na",
                "org": "The Key Laboratory of Optoelectronic Technology and Systems of the Education Ministry,Chongqing University,Chongqing ,China"
            }
        ],
        "venue": "Acta Photonica Sinica",
        "year": 2007
    },
    "4KD45HVR": {
        "id": "4KD45HVR",
        "title": "Cable Tension in Situ Measurement Based on the Magneto-elastic Effect for the Cable Bridges",
        "abstract": "Aimed at the in situ detection for the cable tension of the large band cable bridges,a new in situ measurement method of cable tension based on magneto-elastic effect is introduced,it's measurement principle is described,the structure of magnetic circuit is analyzed,the effect of the magnetic intensity and temperature on measurement is studied,the experiment system is designed.Confirmed the magnetic intensity and the temperature effect curve is optimized by experiment,finally,the experiment of pulling tension is carried on,the experiment results indicated that this method is feasible,it's repetition is better than 0.2%.",
        "keywords": [
            "Cable bridge",
            "magneto-elastic effect",
            "cable tension",
            "permeability"
        ],
        "authors": [
            {
                "name": "Tang Dedong",
                "org": "Key Lab.For Optoelectronic Tech.and Systems of MOE,Dept.of Optoelectronic Eng.Chongqing University,Chongqing ,China;Logistic Engineer Institute,Chongqing ,China"
            },
            {
                "name": "Huang Shanglian",
                "org": "Key Lab.For Optoelectronic Tech.and Systems of MOE,Dept.of Optoelectronic Eng.Chongqing University,Chongqing ,China"
            },
            {
                "name": "Chen Weimin",
                "org": "Key Lab.For Optoelectronic Tech.and Systems of MOE,Dept.of Optoelectronic Eng.Chongqing University,Chongqing ,China"
            },
            {
                "name": "Liao Changrong",
                "org": "Key Lab.For Optoelectronic Tech.and Systems of MOE,Dept.of Optoelectronic Eng.Chongqing University,Chongqing ,China"
            },
            {
                "name": "Zhang Jie",
                "org": "Key Lab.For Optoelectronic Tech.and Systems of MOE,Dept.of Optoelectronic Eng.Chongqing University,Chongqing ,China"
            }
        ],
        "venue": "Modern Scientific Instruments",
        "year": 2007
    },
    "K0s9rR1x": {
        "id": "K0s9rR1x",
        "title": "The Optimum Grayscale Algorithm Based on Human Visual Characteristics",
        "abstract": "The gray modulation method is introduced in this paper,in which the flaw of the mainstream gray modulation is analyzed.According to the human visual characteristics an advanced algorithm based on the optimum mathematic model is put forward.The feasibility of the algorithm is proved by FPGA hardware and VHDL program.Simulations and analysis indicate that such optimum algorithm can produce better output that fits to the ideal curve.Compared with the former,it improves the peak flicker frequency up to 32 times at 256 grayscale,achieves better color performance,reduces the visible flicker,and enhances the stability of dynamic image.",
        "keywords": [
            "grayscale",
            "optimum model",
            "DLP",
            "MOEMS",
            "PWM",
            "display",
            "algorithm"
        ],
        "authors": [
            {
                "name": "HAN Lei",
                "org": "Key Lab of Optoelectronic Technology and System of MOE,Chongqing University,Chongqing ,China"
            },
            {
                "name": "HUANG Shang-lian",
                "org": "Key Lab of Optoelectronic Technology and System of MOE,Chongqing University,Chongqing ,China"
            },
            {
                "name": "ZHANG Zhi-hai",
                "org": "Key Lab of Optoelectronic Technology and System of MOE,Chongqing University,Chongqing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Key Lab of Optoelectronic Technology and System of MOE,Chongqing University,Chongqing ,China"
            },
            {
                "name": "WU Yi",
                "org": "Key Lab of Optoelectronic Technology and System of MOE,Chongqing University,Chongqing ,China"
            }
        ],
        "venue": "Video Engineering",
        "year": 2007
    },
    "B4mO1Ek4": {
        "id": "B4mO1Ek4",
        "title": "Influence of crab-cantilever on performance of grating moving light modulator",
        "abstract": "The light modulator based on Micro-opto-electro-mechanical System(MEMS) has already become a research focus in projection display field.The structure of Grating Moving Light Modulator(GMLM) supported by four crab-cantilevers is composed of reflection plate,address electrode,four crab-cantilevers and grating plate.In this paper,the influence of crab-cantilevers on GMLM performance was analyzed.The diffraction intensity of GMLM was discussed with Fourier optics,while the grating period number was odd and even integer.Especially,the influence of frame and four crab-cantilevers on GMLM performance was analyzed in detail.The result indicates that frame and crab-cantilever size should be reduced in design for obtaining a higher constrast ratio.Moreover, the relationship between contrast ratio and important structure parameter is shown in figures.",
        "keywords": [
            "diffraction grating",
            "MEMS",
            "grating moving light modulator",
            "Fourier optics"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Key Laboratory of Optoelectronic Technology and Systems,Ministry of Education,Chongqing University,Chongqing ,China"
            },
            {
                "name": "HUANG Shang-lian",
                "org": "Key Laboratory of Optoelectronic Technology and Systems,Ministry of Education,Chongqing University,Chongqing ,China"
            },
            {
                "name": "ZHANG Zhi-hai",
                "org": "Key Laboratory of Optoelectronic Technology and Systems,Ministry of Education,Chongqing University,Chongqing ,China"
            },
            {
                "name": "SUN Ji-yong",
                "org": "Key Laboratory of Optoelectronic Technology and Systems,Ministry of Education,Chongqing University,Chongqing ,China"
            },
            {
                "name": "FU Hong-qiao",
                "org": "Key Laboratory of Optoelectronic Technology and Systems,Ministry of Education,Chongqing University,Chongqing ,China"
            }
        ],
        "venue": "Optics and Precision Engineering",
        "year": 2007
    },
    "Ik0rcr3Y": {
        "id": "Ik0rcr3Y",
        "title": "Experiments of micro-distance measurement for GMLM with spectrum analysis method",
        "abstract": "Projection display devices are undergoing a period of multi-development, and with the maturation of MEMS technology, which leads to MEMS-based light modulators for display applications, have become one of the research focuses. The structure of MEMS-based grating moving light modulator (GMLM) is composed of the reflection plate, address electrode and four cantilevers, and movable grating plate, which is supported by four crab-cantilevers placed around, and is actuated like a piston by electrostatic force. The piston-type motion of grating can be used to modulate the phase of incident light. The micro-distance between the upper surface of movable grating and underlying reflector is a key parameter and is important to GMLM performance. Traditional measurement method such as step-machine would destroy the device; while a high accuracy and non-contact measurement machine called KYKO White Light Interferometer is expensive. In the present paper, the GMLM optical principle using scalar diffraction theory was in details analyzed. A novel non-contact wavelength scanning spectrum analysis method was put forward to measure the distance between the upper surface of movable grating and underlying reflector. The U-4100 spectrophotometer was adopted to gain spectrum information; while the spectrum analysis method using peak wavelength position was introduced to calculate the micro distance. The measurement result is consistent to theoretical result. The micro-distance is 1.131 3 microm using such non-contact wavelength scanning spectrum analysis method, while it is 1.240 0 microm with WYKO White Light Interferometer. The relative error was lower than 1%, compared with the results measured by WYKO White Light Interferometer, and the method has good repetition ability and is cheap with RMB50 Yuan each time. Furthermore, measuring pull-in voltage, resonance frequency and micro distance in MEMS-based diffraction and interference devices was proposed completely based on such non-contact wavelength scanning spectrum analysis method.",
        "keywords": [
            "Light modulator",
            "MEMS",
            "Micro distance",
            "Spectrum"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            },
            {
                "name": "Shang-Lian Huang",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            },
            {
                "name": "Zhi-Hai Zhang",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            },
            {
                "name": "Ji-Yong Sun",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            },
            {
                "name": "Ling-Na Shi",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            },
            {
                "name": "Yong Zhu",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            }
        ],
        "venue": "Guang Pu Xue Yu Guang Pu Fen Xi/Spectroscopy and Spectral Analysis",
        "year": 2008
    },
    "76G1Y18O": {
        "id": "76G1Y18O",
        "title": "Analysis and simulation for mechanical characteristics of grating movable light modulator",
        "abstract": "GMLM(grating movable light modulator)is a novel light modulator based on MOEMS technology.Incident light is modulated by a movable grating,which is operated by electrostatic force.Due to its fast switching speed and characteristic of two-dimensional array,it can be used in the fields of display and printing.The electrical and mechanical model of GMLM was established,then mechanical characteristics of GMLM were analyzed by applying mechanics theory and principle of virtual work,and the approximate solution of load-deflection characteristic was gained.Mechanical characteristics of GMLM were also simulated by FEM(finite element method)software-CoventorWare.Simulations show that the theoretical analysis data and the simulation results are highly coincident in the range of deflection that the device needs,the average error is below 5%.",
        "keywords": [
            "Deflection equation",
            "FEM simulation",
            "Light modulator",
            "Mechanical characteristic",
            "MEMS"
        ],
        "authors": [
            {
                "name": "Han Lei",
                "org": "Key Lab of Optoelectronic Technology and System of MOE,Chongqing University,Chongqing ,China"
            },
            {
                "name": "Huang Shanglian",
                "org": "Key Lab of Optoelectronic Technology and System of MOE,Chongqing University,Chongqing ,China"
            },
            {
                "name": "Zhang Jie",
                "org": "Key Lab of Optoelectronic Technology and System of MOE,Chongqing University,Chongqing ,China"
            },
            {
                "name": "He Xuefeng",
                "org": "Key Lab of Optoelectronic Technology and System of MOE,Chongqing University,Chongqing ,China"
            },
            {
                "name": "Wu Yi",
                "org": "Key Lab of Optoelectronic Technology and System of MOE,Chongqing University,Chongqing ,China"
            }
        ],
        "venue": "Chinese Journal of Scientific Instrument",
        "year": 2008
    },
    "dN7J4N98": {
        "id": "dN7J4N98",
        "title": "Effect of Trapped Charges on GMLM Pull-Out Voltage",
        "abstract": "A grating moving light modulator (GMLM) modulates light energy by changing the distance of the movable grating and the underlying fixed reflector.The dielectric material SiO2 provides trap sites for charges both in the volume and the surface in high electric field,which will affect GMLM driving characteristic.With Gauss theory,the electrodynamic model is set up.The distribution of trapped charges and the relationship between the displacement of movable grating and applied voltage are analyzed in detail An experimental scheme is designed.The experiment indicates that increasing the applied voltage achieves the same displacement due to the influence of trapped charges,a longer charge time,and a bigger offset voltage,which is consistent with theoretical analysis.",
        "keywords": [
            "pull-out voltage",
            "grating",
            "trapped charges"
        ],
        "authors": [
            {
                "name": "Zhang Jie",
                "org": "Key Laboratory for Opto-Eletronic Technology & System,Education Ministry of China,Opto-Electronic Engineering Department,Chongqing University,Chongqing ,China"
            },
            {
                "name": "Huang Shanglian",
                "org": "Key Laboratory for Opto-Eletronic Technology & System,Education Ministry of China,Opto-Electronic Engineering Department,Chongqing University,Chongqing ,China"
            },
            {
                "name": "Sun Jiyong",
                "org": "Key Laboratory for Opto-Eletronic Technology & System,Education Ministry of China,Opto-Electronic Engineering Department,Chongqing University,Chongqing ,China"
            },
            {
                "name": "Zhang Zhihai",
                "org": "Key Laboratory for Opto-Eletronic Technology & System,Education Ministry of China,Opto-Electronic Engineering Department,Chongqing University,Chongqing ,China"
            },
            {
                "name": "Zhu Yong",
                "org": "Key Laboratory for Opto-Eletronic Technology & System,Education Ministry of China,Opto-Electronic Engineering Department,Chongqing University,Chongqing ,China"
            }
        ],
        "venue": "Journal of Semiconductors",
        "year": 2008
    },
    "UOUmfqqz": {
        "id": "UOUmfqqz",
        "title": "Analysis and measurement of pull-in voltage of grating moving light modulator based on MOEMS",
        "abstract": "A novel Grating Moving Light Modulator(GMLM)based on MOEMS is introduced.It can form 2D array modulator.The spring and parallel-plate capacitance model of GMLM is analysed;the equation of pull-in voltage is given.Moreover,considering the fringing field effect in electrostatic actuators,an improved equation is deduced. Experiment result is shown,which coincides with the theoretical result.The error between theoretical result and measurement one is only 4.3%。",
        "keywords": [
            "fringing field effect",
            "MOEMS",
            "grating moving light modulator",
            "pull-in voltage"
        ],
        "authors": [
            {
                "name": "Zhang Zhihai",
                "org": " The Key Laboratory for Opto-eletronic Technology & System under Ministry of Education, Chongqing University,Chongqing ,China 2 National Key Laboratory of Fundamental Science of Micro/Nano-Device and System Technology, Chongqing University,Chongqing ,China"
            },
            {
                "name": "Zhang Jie",
                "org": " The Key Laboratory for Opto-eletronic Technology & System under Ministry of Education, Chongqing University,Chongqing ,China 2 National Key Laboratory of Fundamental Science of Micro/Nano-Device and System Technology, Chongqing University,Chongqing ,China"
            },
            {
                "name": "Jin Zhu",
                "org": " The Key Laboratory for Opto-eletronic Technology & System under Ministry of Education, Chongqing University,Chongqing ,China 2 National Key Laboratory of Fundamental Science of Micro/Nano-Device and System Technology, Chongqing University,Chongqing ,China"
            },
            {
                "name": "Wang Ning",
                "org": " The Key Laboratory for Opto-eletronic Technology & System under Ministry of Education, Chongqing University,Chongqing ,China 2 National Key Laboratory of Fundamental Science of Micro/Nano-Device and System Technology, Chongqing University,Chongqing ,China"
            }
        ],
        "venue": "Chinese Journal of Scientific Instrument",
        "year": 2009
    },
    "U0POdtWx": {
        "id": "U0POdtWx",
        "title": "Experiments of a grating light modulator for projection display applications",
        "abstract": "A micromechanical optical modulator called a grating light modulator (GLM) with electrostatic actuation, fabricated by the conventional process, is described. The GLM is operated by the interaction of a stationary reflector and a movable sliding grating. The GLM is a micromechanical phase grating. The phase difference is determined by the slide of the movable part (upper grating), allowing different diffraction patterns of reflected light. In addition, 100% modulation in the first/zero order can act as an optical switch and produce bright or dark pixels in a projection display system. Built using microelec- tromechanical system technology, and designed to be manufactured using mainstream integrated circuit fabrication technology, a 256-pixel GLM array is fabricated. We also describe projection display applications of a GLM as a high efficiency spatial light modulator. The optimized display system with a GLM is theoretically discussed in detail. The single-color and three-color experimental results indicate that the GLM technology has characteristics that make it suitable for projection display applications. © 2009 Optical Society of America.",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            },
            {
                "name": "Yong Zhu",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            },
            {
                "name": "Jiyong Sun",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            },
            {
                "name": "Ning Wang",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            },
            {
                "name": "Wei Wei",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            }
        ],
        "venue": "Applied Optics",
        "year": 2009
    },
    "kZVgLRON": {
        "id": "kZVgLRON",
        "title": "Analysis and Experiments on Multi-Color Projection Scheme Based on Grating Light Modulator",
        "abstract": "A multi-color projection scheme based on single grating light modulator (GLM) using three-color lasers as light source is proposed. First, the principle of color display is explained. Second, red, green and blue laser composing standard D65 white light source is analyzed by colorimetry theory, considering three important indicators, displaying reduction degree of color, displaying brightness and output power of laser. The laser light source is analyzed and optimized. The result indicates that the combination of the lasers with wavelengths of 635, 532 and 457 nm is the best optimal project. The experiment system is set up, and the color projection experiment based on static grating light modulators is carried out by collecting the ±1st order diffraction light. Red, green, blue and white projection pattern is obtained through the experiment, which preliminarily proves the validity of this color projection scheme.",
        "keywords": [
            "micro-electro-mechanical systems",
            "grating light modulator",
            "projection",
            "colorimetry",
            "multi-color"
        ],
        "authors": [
            {
                "name": "Wei Wei",
                "org": "Key Laboratory of Opto-Electronic Technology and Systems, Ministry of Education,Chongqing University, Chongqing , China"
            },
            {
                "name": "Chen Weimin",
                "org": "Key Laboratory of Opto-Electronic Technology and Systems, Ministry of Education,Chongqing University, Chongqing , China"
            },
            {
                "name": "Wang Ning",
                "org": "Key Laboratory of Opto-Electronic Technology and Systems, Ministry of Education,Chongqing University, Chongqing , China"
            },
            {
                "name": "Qin Yi",
                "org": " Optoelectronic Engineering Department, Chongqing University, Chongqing , China"
            },
            {
                "name": "Shi Lingna",
                "org": " Optoelectronic Engineering Department, Chongqing University, Chongqing , China"
            },
            {
                "name": "Zhang Jie",
                "org": "Key Laboratory of Opto-Electronic Technology and Systems, Ministry of Education,Chongqing University, Chongqing , China"
            }
        ],
        "venue": "Laser & Optoelectronics Progress",
        "year": 2010
    },
    "zPHba7SO": {
        "id": "zPHba7SO",
        "title": "A novel near-infrared spectra detection system based on MEMS grating light modulators]",
        "abstract": "A novel near-infrared spectrum detection system based on grating light modulators is proposed in the present paper. A new spectrum detection method that combines MEMS grating light modulators with a single near infrared detector is applied in the system, which can avoid using costly near infrared detector array. Firstly, the optical structure of the spectra detection system was designed. Secondly, the spectra detection principle of this system was addressed in detail that with a series of voltages actuated on the grating light modulators array, the optical energy of each wavelength is reflected onto the single near-infrared detector by corresponding grating light modulator pixel orderly and the transmission spectra can be acquired after a scanning period. Finally, the grating light modulators array device was fabricated by surface micromachining processing and a near-infrared spectra detection system was set up to test the key parameters such as resolving power, wavelength accuracy, system stability and response characteristics of grating light modulators. The experimental results illuminated that the spectrum range of this spectra detection system is from 1 320 to 1 400 nm, the resolving power is below 10 nm, the wavelength accuracy is within 1 nm, the stability of the system is below 0.5% and the response frequency is 5 kHz. The results of theory analysis and experiments demonstrated the feasibility of the spectra detection system. It could give theoretical and experimental guidance to the design and fabrication of miniature near-infrared spectrometer based on grating light modulators.",
        "keywords": [
            "mems",
            "near-infrared",
            "grating light modulator",
            "spectra detection system"
        ],
        "authors": [
            {
                "name": "Wei Wei",
                "org": " College of Optoelectronic Engineering,Chongqing University and Key Laboratory for Optoelectronic Technology & System,Ministry of Education,Chongqing ,China"
            },
            {
                "name": "Shang-Lian Huang",
                "org": " College of Optoelectronic Engineering,Chongqing University and Key Laboratory for Optoelectronic Technology & System,Ministry of Education,Chongqing ,China"
            },
            {
                "name": "Wei-Min Chen",
                "org": " College of Optoelectronic Engineering,Chongqing University and Key Laboratory for Optoelectronic Technology & System,Ministry of Education,Chongqing ,China"
            },
            {
                "name": "Ning Wang",
                "org": " College of Optoelectronic Engineering,Chongqing University and Key Laboratory for Optoelectronic Technology & System,Ministry of Education,Chongqing ,China"
            },
            {
                "name": "Jie Zhang",
                "org": " College of Optoelectronic Engineering,Chongqing University and Key Laboratory for Optoelectronic Technology & System,Ministry of Education,Chongqing ,China"
            },
            {
                "name": "Yong Zhu",
                "org": " College of Optoelectronic Engineering,Chongqing University and Key Laboratory for Optoelectronic Technology & System,Ministry of Education,Chongqing ,China"
            }
        ],
        "venue": "Guang pu xue yu guang pu fen xi = Guang pu",
        "year": 2010
    },
    "dUVqU20j": {
        "id": "dUVqU20j",
        "title": "The principle and analysis of micro-fourier transform spectrometer based on MEMS micro-mirror",
        "abstract": "The present paper puts forward a novel micro-Fourier transform infrared spectrometer based on programmable MEMS micro-mirror. This design uses a MEMS micro-mirror and a slantwise reflector to replace the moving mirror system on traditional spectrometer. This paper analyzes the operating principle of this spectrometer and gives the simulation result to prove the feasibility of this method. The results show that the spectral resolution is less than 5 nm in near-infrared wave band, the wave-length accuracy is approximately 1 nm and the sampling period of this spectrometer is approximately 50 ms. This method can use Hadamard transform to improve the SNR.",
        "keywords": [
            "Fourier transform",
            "MEMS",
            "Spectrum"
        ],
        "authors": [
            {
                "name": "Jian-Jun Chen",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            },
            {
                "name": "Yong Zhu",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            },
            {
                "name": "Bo Liu",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            },
            {
                "name": "Wei Wei",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            },
            {
                "name": "Ning Wang",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            }
        ],
        "venue": "Guang Pu Xue Yu Guang Pu Fen Xi/Spectroscopy and Spectral Analysis",
        "year": 2012
    },
    "w1rSdGj9": {
        "id": "w1rSdGj9",
        "title": "An open path trace gas detection sensor system based on quartz enhanced photoacoustic spectroscopy",
        "abstract": "To overcome such disadvantages as large volume, low real-time and inability to detect trace gas in narrow space in the conventional quartz enhanced photoacoustic spectroscopy (QEPAS) system, a trace gas detection sensor system based on fiber lead open path QEPAS is investigated. The laser source is led to the central of two pins of the tuning fork (TF) by a fiber to realize the detection in narrow space. The experiment for detection of water vapour in the open environment was carried out to evaluate the sensitivity and stability of the system. A normalized noise equivalent absorption coefficient 7.15×10-7 cm-1·W/Hz1/2 is achieved, which is about 5 times higher than that of conventional focus mode. The system has such advantages: small size, hard real-time, without sample sampling, and applied to the detection of trace gases in the open environment.",
        "keywords": [
            "Gas sensing",
            "Open path",
            "Photoacoustic spectroscopy",
            "Quartz tuning fork"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            },
            {
                "name": "Yong Zhu",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            },
            {
                "name": "Wei Wei",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            },
            {
                "name": "Cheng Lin",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            },
            {
                "name": "Li Tian",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            },
            {
                "name": "Zuwen Xu",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            }
        ],
        "venue": "Chinese Journal of Sensors and Actuators",
        "year": 2013
    },
    "r3c0vI0o": {
        "id": "r3c0vI0o",
        "title": "Quartz-enhanced photoacoustic spectroscopy trace gas detection system based on the Fabry-Perot demodulation",
        "abstract": "An all-optical quartz-enhanced photoacoustic spectroscopy system, based on the F-P demodulation, for trace gas detection in the open environment was proposed. In quartz-enhanced photoacoustic spectroscopy (QEPAS), an optical fiber Fabry-Perot method was used to replace the conventional electronic demodulation method. The photoacoustic signal was obtained by demodulating the variation of the Fabry-Perot cavity between the quartz tuning fork side and the fiber face. An experimental system was setup. The experiment for detection of water vapour in the open environment was carried on. A normalized noise equivalent absorption coefficient of 2.80 x 10(-7) cm(-1) x W x Hz(-1/2) was achieved. The result demonstrated that the sensitivity of the all-optical quartz-enhanced photoacoustic spectroscopy system is about 2.6 times higher than that of the conventional QEPAS system. The all-optical quartz-enhanced photoacoustic spectroscopy system is immune to electromagnetic interference, safe in flammable and explosive gas detection, suitable for high temperature and high humidity environments and realizable for long distance, multi-point and network sensing.",
        "keywords": [
            "Fabry-Perot demodulation",
            "Photoacoustic spectroscopy",
            "Quartz-enhanced",
            "Trace gas detection"
        ],
        "authors": [
            {
                "name": "Cheng Lin",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            },
            {
                "name": "Yong Zhu",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            },
            {
                "name": "Wei Wei",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            },
            {
                "name": "Li Tian",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            },
            {
                "name": "Zu-Wen Xu",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            }
        ],
        "venue": "Guang Pu Xue Yu Guang Pu Fen Xi/Spectroscopy and Spectral Analysis",
        "year": 2013
    },
    "YAZCepyC": {
        "id": "YAZCepyC",
        "title": "Experimental study of Fourier transform spectrometer based on MEMS micro-mirror",
        "abstract": "We propose a new Fourier transform spectrometer based on programmable microelectromechanical systems(MEMS) micro-mirror and an improved Michelson interferometer.The principle of the spectrometer is theoretically analyzed.A signal acquisition unit and an experimental set-up are designed.The spectrum of the polychromatic light source is obtained at a slantwise reflector angle of 0.238°.The spectrum is analyzed by this system within the near infrared.The experimental results show that the spectral accuracy is less than 3 nm,and the signal-to-noise ratio(SNR) is 18 dB.The spectral resolution is less than 16 nm.",
        "keywords": [
            "spectrometers",
            "spectroscopy"
        ],
        "authors": [
            {
                "name": "Jianjun Chen",
                "org": " College of Optoelectronic Engineering,Chongqing University,Chongqing ,China"
            },
            {
                "name": "Yong Zhu",
                "org": " College of Optoelectronic Engineering,Chongqing University,Chongqing ,China"
            },
            {
                "name": "Bo Liu",
                "org": " College of Optoelectronic Engineering,Chongqing University,Chongqing ,China"
            },
            {
                "name": "Wei Wei",
                "org": " College of Optoelectronic Engineering,Chongqing University,Chongqing ,China"
            },
            {
                "name": "Ning Wang",
                "org": " College of Optoelectronic Engineering,Chongqing University,Chongqing ,China"
            },
            {
                "name": "Jie Zhang",
                "org": " College of Optoelectronic Engineering,Chongqing University,Chongqing ,China"
            }
        ],
        "venue": "中国光学快报(英文版)",
        "year": 2013
    },
    "6sucyS6O": {
        "id": "6sucyS6O",
        "title": "Analysis of Tolerance of Tilting Mirror and Experiment in Novel Fourier Transform Spectrometer",
        "abstract": "Equipped with a tilt mirror and micro-mirror replacing the moving mirror,a novel Fourier transform spectrometer is proposed based on programmable Micro-Electro-Mechanical Systems(MEMS) micro-mirror.Firstly,the working principle and the tolerance of the tilting mirror is analyzed systematically and validated experimentally.Theory results show that the limited tilt angle is 0.52° and the spectrum resolution is 8 nm in the near infrared region;while the limited tilt angle is 0.183°,the spectrum resolution is 3 nm in the visible region.Experimental measurement shows that the spectra can be reconstructed accurately in the tolerance of the tilting mirror with central wavelength 488 nm laser soure and polychromatic light soure,while distorted badly out of the tolerance range.",
        "keywords": [
            "Micro-Electro-Mechanical Systems(MEMS)",
            "Spectrum",
            "Fourier transform"
        ],
        "authors": [
            {
                "name": "LIU Bo",
                "org": "College of Optoelectronic Engineering,Chongqing University,Chongqing ,China"
            },
            {
                "name": "ZHU Yong",
                "org": "College of Optoelectronic Engineering,Chongqing University,Chongqing ,China"
            },
            {
                "name": "CHEN Jian-jun",
                "org": "College of Optoelectronic Engineering,Chongqing University,Chongqing ,China"
            },
            {
                "name": "WEI Wei",
                "org": "College of Optoelectronic Engineering,Chongqing University,Chongqing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "College of Optoelectronic Engineering,Chongqing University,Chongqing ,China"
            },
            {
                "name": "WANG Ning",
                "org": "College of Optoelectronic Engineering,Chongqing University,Chongqing ,China"
            }
        ],
        "venue": "Acta Photonica Sinica",
        "year": 2013
    },
    "vcnh2tfw": {
        "id": "vcnh2tfw",
        "title": "Light-induced vibration characteristics of free-standing carbon nanotube films fabricated by vacuum filtration",
        "abstract": "",
        "keywords": [
            "carbon nanotubes",
            "filtration",
            "surfaces",
            "fabry perot interferometer",
            "wavelengths",
            "absorptivity",
            "quantum entanglement",
            "membranes",
            "spectra",
            "films",
            "simulation"
        ],
        "authors": [
            {
                "name": "junying li",
                "org": ""
            },
            {
                "name": "yong zhu",
                "org": ""
            },
            {
                "name": "xin wang",
                "org": ""
            },
            {
                "name": "ning wang",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            }
        ],
        "venue": "Journal of Applied Physics",
        "year": 2014
    },
    "sR7H5Ecx": {
        "id": "sR7H5Ecx",
        "title": "Experimental Study of a Fourier Transform Spectrometer Based on Scanning Micro-Electromechanical Mirrors",
        "abstract": "",
        "keywords": [
            "infrared",
            "mems"
        ],
        "authors": [
            {
                "name": "jianjun chen",
                "org": ""
            },
            {
                "name": "yong zhu",
                "org": ""
            },
            {
                "name": "wei wei",
                "org": ""
            },
            {
                "name": "yang li",
                "org": ""
            },
            {
                "name": "yining yang",
                "org": ""
            },
            {
                "name": "ning wang",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            }
        ],
        "venue": "Spectroscopy Letters",
        "year": 2014
    },
    "mWHkHdHq": {
        "id": "mWHkHdHq",
        "title": "Three-dimensional multi-walled carbon nanotube arrays coated by gold-sol as a surface-enhanced Raman scattering substrate.",
        "abstract": "We demonstrated a three-dimensional (3D) surface-enhanced Raman scattering (SERS) substrate consisting of large area carbon nanotube (CNT) arrays coated by gold-sol nanoparticles. A low-cost, simple process is used to prepare Au-decorated 3D CNT arrays. The SERS enhancement from the 3D CNT arrays, and two-dimensional (2D) CNT films substrates coated by different size gold-sol nanoparticles, was experimentally verified with Rhodamine 6G as the probe analyte. The experiments showed that the 3D CNT arrays substrate has a higher Raman enhancement compared with 2D CNT arrays substrate and planar glass substrate, due to the large specific surface area of CNT arrays and more gold nanoparticles on the CNT arrays sidewalls, which contribute the electromagnetic field and Raman intensity. Meanwhile, the 3D structure could enhance the excitation light trapping in CNT arrays, consequently increasing the light interaction with Au nanoparticles.",
        "keywords": [],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Tuo Fan",
                "org": ""
            },
            {
                "name": "Xiaolei Zhang",
                "org": ""
            },
            {
                "name": "Chunhong Lai",
                "org": ""
            },
            {
                "name": "Yong Zhu",
                "org": ""
            }
        ],
        "venue": "Applied optics",
        "year": 2014
    },
    "B48IcCRL": {
        "id": "B48IcCRL",
        "title": "Study on modification of single-walled carbon nanotubes on the surface of monocrystalline silicon solar cells.",
        "abstract": "Modification of single-walled carbon nanotubes (SWNTs) on the surface of monocrystalline silicon solar cells was investigated. The modification was realized by dropping a well-distributed mixture of SWNTs and ethanol with different dosages on the surface of monocrystalline silicon solar cells in the same effective area. The experimental results showed that the increasing rates of conversion efficiency, short-circuit current, and fill factor were 4.37%, 2.18%, and 2.11%, respectively; the open circuit voltage and series resistance decreased by 0.11% and 9.37% compared with the bare solar cell without an antireflection (AR) layer, when the modification reached the best state by dropping a 0.5 mL mixture solution with a concentration of 0.08  g/L. With the energy-band diagrams of the heterojunction and p-n junction, the principles of the modification of SWNTs on monocrystalline silicon solar cells and the reasons for the change of electrical parameters were analyzed theoretically. Through experiments and theoretical analyses, the modification of SWNTs on solar cells is a potential and effective way to improve the performance of solar cells.",
        "keywords": [
            "nanomaterials",
            "silicon",
            "photovoltaic"
        ],
        "authors": [
            {
                "name": "Tiancheng Gong",
                "org": ""
            },
            {
                "name": "Yong Zhu",
                "org": ""
            },
            {
                "name": "Wenbin Xie",
                "org": ""
            },
            {
                "name": "Ning Wang",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Wenjie Ren",
                "org": ""
            }
        ],
        "venue": "Applied optics",
        "year": 2014
    },
    "FNm3rkoo": {
        "id": "FNm3rkoo",
        "title": "A phase error correction method for the new Fourier transforms spectrometer]",
        "abstract": "To decrease the distortion of the recovered spectrum, improve the quantity of the recovered spectrum and decrease the influence of the phase error of the new spectrum detection system based on MEMS (micro-electro-mechanical systems) micro-mirrors, a new phase error correction method for this system is proposed in the present paper. The source of phase error of the spectrum detection system based on MEMS micro-mirrors is analyzed firstly. The analyzed result indicated that the phase error of the new spectral Fourier transform detection system is the zero drift of the optical path difference, and the phase error can be corrected by Zero-crossing sampling which is realized by improving the structure of the interferometer system and Mertz product The spectrum detection system is set up and the phase error correction method is verified by this system. The experiment result is show that the quantity of the recovered spectrum of the spectrum detection is improved obviously by using the improved interferometer system and Mertz product, and the recovered spectrum has no negative peaks and the side lobes is suppressed markedly. This correction method can reduce the influence caused by phase error to the system performance well and improve the spectral detection performance effectively. In this paper, the origin of the system phase error based on the new MEMS micromirror Fourier transform spectroscopy detection system is analyzed, and the phase error correction method is proposed. This method can improve the performance of the spectrum detection system.",
        "keywords": [],
        "authors": [
            {
                "name": "Ning Wang",
                "org": ""
            },
            {
                "name": "Tian-Cheng Gong",
                "org": ""
            },
            {
                "name": "Jian-Jun Chen",
                "org": ""
            },
            {
                "name": "Yang Li",
                "org": ""
            },
            {
                "name": "Yi-Ning Yang",
                "org": ""
            },
            {
                "name": "Yong Zhu",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Wei-Min Chen",
                "org": ""
            }
        ],
        "venue": "Guang pu xue yu guang pu fen xi = Guang pu",
        "year": 2014
    },
    "NpFKv1m8": {
        "id": "NpFKv1m8",
        "title": "Study on surface-enhanced Raman scattering substrates structured with hybrid Ag nanoparticles and few-layer graphene",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "tiancheng gong",
                "org": ""
            },
            {
                "name": "yong zhu",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "wenjie ren",
                "org": ""
            },
            {
                "name": "jiamin quan",
                "org": ""
            },
            {
                "name": "ning wang",
                "org": ""
            }
        ],
        "venue": "Carbon",
        "year": 2015
    },
    "BjWuebnA": {
        "id": "BjWuebnA",
        "title": "Study on single-walled carbon nanotube thin film photoelectric device]",
        "abstract": "The single-walled carbon nanotube film photoelectric device was invented, and it can generate net photocurrent under bias voltage when it is illuminated by the laser. The influences of bias voltage, laser power and illuminating position on the net photocurrent were investigated. The experimental results showed that when the center of the film was illuminated, the photocurrent increased with the applied bias, but tended to saturate as the laser power increased. As the voltage and the laser power reached 0. 2 V and 22. 7 mW respectively, the photocurrent reached 0. 24 µA. When the voltage was removed, the photocurrent varied with the laser illuminating position on the film and its value was distributed symmetrically about the center of the device. The photocurrent reached maximum and almost zero respectively when the laser illuminated on two ends and the center of the film. Analysis proposes that the net photocurrent can be generated due to internal photoelectric effect when the device is under voltage and the laser illuminates on the center of the film. It can be also generated due to photo-thermoelectric effect when the device is under no voltage and the laser illuminates on the film, and the relation between the net photocurrent and the illuminating position was derived according to the nature of thermoelectric power of single-walled carbon nanotubes with the established temperature model, which coincides with experimental result. Two effects are the reasons for the generation and variety of the net photocurrent and they superimpose to form the result of the net photocurrent when the device is under general conditions of voltage and laser illuminating position. The device has potential applications in the areas of photovoltaic device and optical sensor for its characteristic.",
        "keywords": [],
        "authors": [
            {
                "name": "Wen-bin Xie",
                "org": ""
            },
            {
                "name": "Yong Zhu",
                "org": ""
            },
            {
                "name": "Tian-cheng Gong",
                "org": ""
            },
            {
                "name": "Yu-lin Chen",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            }
        ],
        "venue": "Guang pu xue yu guang pu fen xi = Guang pu",
        "year": 2015
    },
    "9xReffMv": {
        "id": "9xReffMv",
        "title": "Surface-enhanced Raman scattering activities of carbon nanotubes decorated with silver nanoparticles.",
        "abstract": "We synthesized a carbon nanotube (CNT) loaded with silver nanoparticles (AgNPs) composite as an effective surface enhanced Raman scattering (SERS) substrate via a low-cost, simple citrate reduction method. The hybrid materials were confirmed by scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDS), X-ray diffraction (XRD), ultraviolet-visible (UV-vis) spectrophotometer and Raman spectroscopy. Rhodamine 6G (R6G) was used as the probe analyte. The experimental results indicated that the detection concentration level was down to 10(-14) M. Additionally, we discussed the uniformity by conducting SERS position mapping within an area of 5 μm × 5 μm; meanwhile, we performed time-course SERS mapping experiments to study the evaporation process of probe molecules of the prepared samples. Finally, we simulated the electromagnetic field distribution based on SEM images (obtained the ratio of surface area to the area of silver particles) by the finite difference time domain (FDTD) method. ",
        "keywords": "",
        "authors": [
            {
                "name": "Xiaolei Zhang",
                "org": "The Key Laboratory of Optoelectronic Technology & System, Education Ministry of China, Chongqing University, 400044, China. zhangjie@cqu.edu.cn."
            },
            {
                "name": "Jie Zhang",
                "org": "The Key Laboratory of Optoelectronic Technology & System, Education Ministry of China, Chongqing University,,China"
            },
            {
                "name": "Jiamin Quan",
                "org": "The Key Laboratory of Optoelectronic Technology & System, Education Ministry of China, Chongqing University,,China"
            },
            {
                "name": "Ning Wang",
                "org": "The Key Laboratory of Optoelectronic Technology & System, Education Ministry of China, Chongqing University,,China"
            },
            {
                "name": "Yong Zhu",
                "org": "The Key Laboratory of Optoelectronic Technology & System, Education Ministry of China, Chongqing University,,China"
            }
        ],
        "venue": "The Analyst",
        "year": 2016
    },
    "KlQSEBpr": {
        "id": "KlQSEBpr",
        "title": "Preparation of graphene-Ag nanoparticles hybrids and their SERS activities",
        "abstract": "Abstract   Surface-enhanced Raman scattering (SERS) substrates based on graphene and Ag nanoparticles hybrid structures with low cost, high uniformity were prepared by a standard process of immobilization of silver nanoparticles with 3-aminopropyltrimethoxysilane (APTMS). Thermal annealing was used for removing residual APTMS and adjusting the morphology of silver nanoparticles, and the effectiveness of this method was verified experimentally. The influence of annealing temperature, dipping duration, and APTMS volume on the distribution of Ag nanoparticles and Raman enhancement was investigated experimentally and analyzed in detail. Our samples were prepared under the preparation conditions of 10%  ν / ν  APTMS, dipping time of 48 h, annealing temperature of 450 °C, duration of 30 min, and Ar flow rate of 40 sccm. SERS activities with enhancement of 10 7  and relative standard deviation of  −6  M and 10 −7  M.",
        "keywords": "",
        "authors": [
            {
                "name": "Xinyu Wang",
                "org": "The Key Laboratory of Optoelectronic Technology & System, Education Ministry of China, Chongqing University, 400044, China"
            },
            {
                "name": "Ning Wang",
                "org": "The Key Laboratory of Optoelectronic Technology & System, Education Ministry of China, Chongqing University, 400044, China"
            },
            {
                "name": "Tiancheng Gong",
                "org": "The Key Laboratory of Optoelectronic Technology & System, Education Ministry of China, Chongqing University, 400044, China"
            },
            {
                "name": "Yong Zhu",
                "org": "The Key Laboratory of Optoelectronic Technology & System, Education Ministry of China, Chongqing University, 400044, China"
            },
            {
                "name": "Jie Zhang",
                "org": "The Key Laboratory of Optoelectronic Technology & System, Education Ministry of China, Chongqing University, 400044, China"
            }
        ],
        "venue": "Applied Surface Science",
        "year": 2016
    },
    "Yz2TSaiO": {
        "id": "Yz2TSaiO",
        "title": "Optical properties and surface-enhanced Raman scattering of hybrid structures with Ag nanoparticles and graphene",
        "abstract": "Abstract   Two kinds of surface-enhanced Raman scattering (SERS) substrates structured with hybrid of Ag nanoparticles (AgNPs) and graphene (GE) were synthesized, namely GE underneath AgNPs (AgNPs-GE) and GE covered AgNPs (GE-AgNPs). They provide a platform to make a comparative study on the optical properties and SERS effects of the hybrid structures as well as on the interactions between AgNPs and GE. The localized surface plasmon resonance (LSPR) of AgNPs exhibits a ∼24/∼16 nm red-shift and a ∼24/∼17 nm broadening at the presence of GE underneath/covered AgNPs. The Raman intensity of GE underneath (covered) AgNPs is enhanced by 7.15/4.76 folds at G peak due to the SERS effects and plasmonic coupling, and the position of G peak is upshifted by 5.69/5.21 cm −1 , 2D peak is upshifted/downshifted by 2.33/9.75 cm −1 , which is caused by strain and doping effects. A “vector decomposition method” was used to decompose the total values of position into the variations induced by strain and doping. Through experiments and analyses, we demonstrated that for AgNPs-GE, compressive strain is the primary cause and the secondary is n-type doping. For GE-AgNPs, n-type doping is the primary cause and the secondary is tensile strain.",
        "keywords": "",
        "authors": [
            {
                "name": "Tiancheng Gong",
                "org": "The Key Laboratory of Optoelectronic Technology & System, Education Ministry of China, Chongqing University, 400044, China"
            },
            {
                "name": "Jie Zhang",
                "org": "The Key Laboratory of Optoelectronic Technology & System, Education Ministry of China, Chongqing University, 400044, China"
            },
            {
                "name": "Yong Zhu",
                "org": "College of Opto-electronic Engineering, Chongqing University, 400044, China"
            },
            {
                "name": "Xinyu Wang",
                "org": "The Key Laboratory of Optoelectronic Technology & System, Education Ministry of China, Chongqing University, 400044, China"
            },
            {
                "name": "Xiaolei Zhang",
                "org": "The Key Laboratory of Optoelectronic Technology & System, Education Ministry of China, Chongqing University, 400044, China"
            },
            {
                "name": "Jing Zhang",
                "org": "The Key Laboratory of Optoelectronic Technology & System, Education Ministry of China, Chongqing University, 400044, China"
            }
        ],
        "venue": "Carbon",
        "year": 2016
    },
    "l4SOMr2c": {
        "id": "l4SOMr2c",
        "title": "ZnO/graphene/Ag composite as recyclable surface-enhanced Raman scattering substrates.",
        "abstract": "Surface-enhanced Raman scattering active substrates based on ZnO/Ag and ZnO/graphene/Ag were prepared via synthesis of ZnO nanorod arrays through the ZnO seed layers, followed by deposition of Ag nanoparticles onto ZnO and ZnO/graphene surfaces using photocatalytic deposition. The hybrid structures were confirmed by scanning electron microscopy and Raman spectroscopy. Rhodamine 6G (R6G) was used as the probe analyte. The experimental results indicated that the detection concentration level was 10<sup>-7</sup>  M with an enhancement factor of about 1.6×10<sup>5</sup>. Additionally, the photocatalytic properties of ZnO/Ag and ZnO/graphene/Ag were exploited to recycle these substrates through UV-assisted cleaning.",
        "keywords": "",
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Key Laboratory for Optoelectronic Technology & Systems, Educational Ministry of China, Chongqing University, Chongqing 400044, China"
            },
            {
                "name": "Xiaolei Zhang",
                "org": "Key Laboratory for Optoelectronic Technology & Systems, Educational Ministry of China, Chongqing University, Chongqing 400044, China"
            },
            {
                "name": "Yimin Ding",
                "org": "Key Laboratory for Optoelectronic Technology & Systems, Educational Ministry of China, Chongqing University, Chongqing 400044, China"
            },
            {
                "name": "Yong Zhu",
                "org": "Key Laboratory for Optoelectronic Technology & Systems, Educational Ministry of China, Chongqing University, Chongqing 400044, China"
            }
        ],
        "venue": "Applied optics",
        "year": 2016
    },
    "2f0r2BXS": {
        "id": "2f0r2BXS",
        "title": "Surface-enhanced Raman scattering properties of multi-walled carbon nanotubes arrays-Ag nanoparticles",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "xiaolei zhang",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "simeng chen",
                "org": ""
            },
            {
                "name": "tiancheng gong",
                "org": ""
            },
            {
                "name": "yong zhu",
                "org": ""
            }
        ],
        "venue": "Carbon",
        "year": 2016
    },
    "urJvRUP6": {
        "id": "urJvRUP6",
        "title": "Tapered Fiber Probe Modified by Ag Nanoparticles for SERS Detection",
        "abstract": "A tapered optical fiber fabricated by a simple chemical etching method and modified with Ag nanoparticles (AgNPs) by chemical deposition was evaluated for surface-enhanced Raman scattering (SERS). The fiber probe was used for SERS measurements in both direct and remote scattering modes, yielding desired performance in both scattering configurations. The state of the obtained AgNPs made a significant contribution to the high sensitivity of SERS to Rhodamine 6G (R6G) molecules (down to a concentration of 10 M), and the substrate had an analyst enhancement factor (AEF) on the order of ∼10. Meanwhile, the SERS intensity during the evaporation process was investigated, showing a good stability at the later stage of the evaporation process. The fiber SERS probes demonstrated good reproducibility with the average relative standard deviation (RSD) values being less than 0.2 for the major Raman peaks.",
        "keywords": [
            "Raman scattering",
            "Surface-enhanced Raman scattering",
            "Optical fiber",
            "Nanoparticles"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "The Key Laboratory of Optoelectronic Technology & System, Education Ministry of China,Chongqing University,Chongqing,China"
            },
            {
                "name": "Simeng Chen",
                "org": "The Key Laboratory of Optoelectronic Technology & System, Education Ministry of China,Chongqing University,Chongqing,China"
            },
            {
                "name": "Tianchen Gong",
                "org": "The Key Laboratory of Optoelectronic Technology & System, Education Ministry of China,Chongqing University,Chongqing,China"
            },
            {
                "name": "Xiaolei Zhang",
                "org": "The Key Laboratory of Optoelectronic Technology & System, Education Ministry of China,Chongqing University,Chongqing,China"
            },
            {
                "name": "Yong Zhu",
                "org": "The Key Laboratory of Optoelectronic Technology & System, Education Ministry of China,Chongqing University,Chongqing,China"
            }
        ],
        "venue": "Plasmonics",
        "year": 2016
    },
    "jbaqafWL": {
        "id": "jbaqafWL",
        "title": "Construction and expression of GST and carbon skeleton of amatoxins fusion gene",
        "abstract": "The primer, AT Forl, AT For2 and AT Back, are designed and synthesized for adding-PCR that is used to construct the fusion GST-AT gene. Depending on two-time adding-PCR amplification and the insertion of coding sequence of octapeptide carbon skeleton into the 3' terminus of GST gene, the authors get the masculine recon, pGAT-1, confirmed by sequence determination and analysis, whose ORF is read-through. After IPTG induction and partial purification, SDS-PAGE electrophoresis is employed to detect the gene expression. The expressions of total bacterial proteins are about 21.3%, 22.5%, 19. 32%, 21.73% in E. coli BL21, DH5α, JM109 and Topl0 strains, respectively. Considering the quantity of induced total bacteria, the E. coli BL21 is the best one among the four recipient strains. This article supplies an academic foundation for producing biological active amatoxins.",
        "keywords": [
            "Adding-PCR",
            "Amatoxins",
            "Fusion gene",
            "Glutathione-S-transferase"
        ],
        "authors": [
            {
                "name": "Jian Zhao",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Mei Cao",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "RuoTong Hou",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Yaofeng Chen",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "ZhiRong Yang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            }
        ],
        "venue": "High Technology Letters",
        "year": 2004
    },
    "ZgH5Zo6Z": {
        "id": "ZgH5Zo6Z",
        "title": "Plant regeneration via somatic embryogenesis of Elymus sibiricus cv. 'chuancao No. 2'",
        "abstract": "The mature seeds, mesocotyls, and young leaf tips of Elymus sibiricus L. cv. 'chuancao No. 2' were cultured on Murashige and Skoog (MS) medium supplemented with 5.0 mg/L 2,4-dichlorophenoxyacetic acid (2,4-D) and 0.05 mg/L kinetin in the dark at 26°C, the calluses were produced. The rate of callus regeneration depended on the explants source and plant growth regulators. Plants regenerated from whitish-yellow-coloured compact nodular callus formed after subculturing for 8 weeks. Higher frequency (54%) of shoot differentiation was obtained from the embryo tissues of mature seed than from either mesocotyls (24%) or young leaf tip tissues (6%) when these calluses from different types of explants were cultured on plant regeneration medium containing half strength MS salts supplemented with 0.1 mg/L kinetin, 1.5 mg/L 2,4-D and 20 g/L sucrose. The green plants were rooted within 6 weeks in the root regeneration medium, and over 97% of these soil-established plants were obtained in the greenhouse when potted in a sand and peat mixture medium. © Springer 2006.",
        "keywords": [
            "callus regeneration",
            "elymus sibiricus l. cv. 'chuancao no. 2'",
            "explants",
            "embryos",
            "somatic embryogenesis"
        ],
        "authors": [
            {
                "name": "Daxu X. Li",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Jian Zhao",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Yizheng Zhang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Fei Chen",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Jingqiu Zhu",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Shujun Liu",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "ZhiRong Yang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            }
        ],
        "venue": "Plant Cell, Tissue and Organ Culture",
        "year": 2006
    },
    "xdWAis3N": {
        "id": "xdWAis3N",
        "title": "Transformation of embryogenic calli of Siberian wildrye grass (Elymus sibiricus L. cv. Chuancao No.2) mediated by agrobacterium",
        "abstract": "Formation of embryogenic calli of Siberian wildrye grass (Elymus sibiricus L. cv. Chuancao No.2) was induced from mature seeds as explants, and proliferated on MS medium containing 2,4-D 5.0 mg/L and KT 0.05 mg/L. An effective and stable callus regeneration system was established by optimizing the culture conditions (Tables 1, 2 and Fig.2). After the calli were subcultured 8 weeks, selected the whitish-yellow-coloured compact nodular calli that transformed with plasmid pCAMBIA1304 carrying hygromycin resistance gene (hptII) and Pseudomonas pseudoalcaligenes insecticidal protein gene (ppIP), which was mediated by an Agrobacterium strain EHA105. Resistant plants were obtained after hygromycin selection (Figs.3, 4). Some important factors that affect the transformation efficiency were studied, which included selection pressure, time of embryogenic calli proliferation, OD value of Agrobacterium suspension, temperature, medium and time of co-cultivation, and concentration of antibiotics used for suppressing the overgrowth of Agrobacterium in the course of transformation plant regeneration. This research is the first successful genetic transformation of Elymus sibiricus L. cv. Chuancao No.2 mediated by Agrobacterium.",
        "keywords": [
            "Agrobacterium-medialed transformation",
            "Callus regeneration",
            "Elymus sibiricus L. cv. Chuancao No.2",
            "ppIP"
        ],
        "authors": [
            {
                "name": "Daxu X. Li",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Jian Zhao",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Yi Zhang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Lì Lì",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "LIU Su-Jun",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Fei Chen",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "YANG Zhi-Rong",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            }
        ],
        "venue": "Zhi wu sheng li yu fen zi sheng wu xue xue bao = Journal of plant physiology and molecular biology",
        "year": 2006
    },
    "QYMgv0Bg": {
        "id": "QYMgv0Bg",
        "title": "Genetic diversity of nine populations of the black goat (Capra hircus) in Sichuan, PR China.",
        "abstract": "Sixteen polymorphic primers screened from 100 random primers were selected to analyze the randomly amplified polymorphic DNA (RAPD) of 540 domesticated black goats (Capra hircas) from 9 different geographical populations in Sichuan Province of China. After the test, 170 entirely repeatable RAPD markers representing goat polymorphisms were obtained from the 16 polymorphic primers, the lengths of the markers ranging from 0.1 to 2.5 kb. The genetic distance among the black goat populations ranges from 0.1051 to 0.2978. The similarity coefficient (0.9002) between Jintang and Lezhi black goats was the highest in the 9 populations, followed by the coefficient (0.8953) between Jialing and Yinshan goats, while that between Jiangan and Huili goats was found to be the lowest (0.7424). The coefficient of differentiation among population genes (Gst) was 0.2766, indicating a comparatively low degree of differentiation among the black goat populations. A UPGMA dendrogram constructed from similarity coefficients showed that the two populations from Huili and Baiyu, which are found mostly on the Western Sichuan plateau and in mountainous areas, clustered together, and the other seven populations formed another group. It can also be clearly seen that the Huili and Baiyu populations are very special, and must have been closely related in the past, even though their link with the other populations is quite weak as a result of genetic communication. The results of the experiment offer some crucial scientific data useful for the breeding of black goats.",
        "keywords": [
            "genetic diversity",
            "population",
            "cluster analysis",
            "heterozygosis",
            "black goat",
            "genetic distance"
        ],
        "authors": [
            {
                "name": "Li Li",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Jing-qiu Zhu",
                "org": ""
            },
            {
                "name": "Song Gu",
                "org": ""
            },
            {
                "name": "Qun Sun",
                "org": ""
            },
            {
                "name": "Guang-ming Zhou",
                "org": ""
            },
            {
                "name": "Chang-xiu Fu",
                "org": ""
            },
            {
                "name": "Qiang Li",
                "org": ""
            },
            {
                "name": "Lin-yu Chen",
                "org": ""
            },
            {
                "name": "Da-xu Li",
                "org": ""
            },
            {
                "name": "Su-jun Liu",
                "org": ""
            },
            {
                "name": "Zhi-rong Yang",
                "org": ""
            }
        ],
        "venue": "Zoological science",
        "year": 2006
    },
    "PDbbspkO": {
        "id": "PDbbspkO",
        "title": "Anticancer activity and quantitative analysis of flavone of Cirsium japonicum DC.",
        "abstract": "Cirsium japonicum DC, a traditional Chinese medicine, has been widely used as an antihemorrhagic and diuretic agent. The objective of this study was to perform quantitative analysis of flavone by reversed-phase HPLC and examine the anticancer activity of C. japonicum DC in the S180 and H22 mice. Cirsium japonicum DC was separated and purified with several chromatography techniques and two flavone compounds, pectolinarin and 5,7-dihydroxy-6,4'-dimethoxyflavone, were isolated. The content of these two compounds in the methanol, ethanol, and aqueous extractions respectively was determined by HPLC as follows: pectolinarin 1.87%, 1.65%, 1.27%; 5,7-dihydroxy-6,4'-dimethoxyflavone: 0.515%, 0.42%, 0.221%. Furthermore, the effect of the two flavones on the anticancer activity in S180 and H22 mice was studied. Our research shows that these two flavones greatly inhibit cancer cell growth. The rate of inhibiting S180 mice was 55.77% at 50 mg kg( - 1), and the rate of life lengthening was 99.13% at 50 mg kg( - 1) in H22 mice.",
        "keywords": [
            "pectolinarin",
            "5",
            "4-dimethoxyflavone",
            "cirsium japonicum dc",
            "rt-hplc",
            "aerial part",
            "7-dihydroxy-6",
            "traditional chinese medicine",
            "cell growth",
            "quantitative analysis"
        ],
        "authors": [
            {
                "name": "Sujun Liu",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Daxu Li",
                "org": ""
            },
            {
                "name": "Wei Liu",
                "org": ""
            },
            {
                "name": "Xun Luo",
                "org": ""
            },
            {
                "name": "Rongxian Zhang",
                "org": ""
            },
            {
                "name": "Li Li",
                "org": ""
            },
            {
                "name": "Jian Zhao",
                "org": ""
            }
        ],
        "venue": "Natural product research",
        "year": 2007
    },
    "ZoDz9gvy": {
        "id": "ZoDz9gvy",
        "title": "Genotypic analysis of multidrug-resistant Mycobacterium tuberculosis isolates recovered from central China.",
        "abstract": "DNA sequencing analysis was used to investigate genetic alterations in the rpoB, katG, and inhA regulatory region and embB in 66 Mycobacterium tuberculosis isolates recovered from Central China. Of the 36 multidrug-resistant isolates, 33 (92%) had mutations in the amplified region\n of rpoB. The most frequent mutation (58%, 19/36) was S531L (TCG→TTG). At least one mutation was found in the katG and inhA regulatory region in 83% (30/36) of the multidrug-resistant isolates, and mutations at katG codon 315 were identified in 78% (28/36). Alterations at embB306 may not confer resistance to EMB, and embB306 mutants were more frequently accompanied by rpoB mutations (100%, 16/16) than by katG 315 mutations (75%, 12/16). Our results show that geographic variation in the molecular genetic mechanism is responsible\n for drug resistance in multidrug-resistant M. tuberculosis. This observation will facilitate the development of a rapid molecular drug resistance screening approach for drug-resistant\n M. tuberculosis.\n ",
        "keywords": [
            "mutation",
            "multidrug resistant",
            "mycobacterium tuberculosis",
            "sequence",
            "gene",
            "dna sequence analysis",
            "drug resistance",
            "multidrug resistance",
            "molecular genetics",
            "genetics"
        ],
        "authors": [
            {
                "name": "Shu-Lin Zhang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Hua Qi",
                "org": "Zhengzhou University(Zhengzhou University),Zhengzhou,China"
            },
            {
                "name": "Dun-Lian Qiu",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Da-Xu Li",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Chang-Mei Du",
                "org": "Henan Chest Hospital(Henan Chest Hospital,Central Laboratory of Henan Provincial Chest Hospital,Henan Tumour Hospital,Henan Provincial Chest Hospital),Zhengzhou,China"
            },
            {
                "name": "Guo-Bin Wang",
                "org": "Henan Chest Hospital(Henan Chest Hospital,Central Laboratory of Henan Provincial Chest Hospital,Henan Tumour Hospital,Henan Provincial Chest Hospital),Zhengzhou,China"
            },
            {
                "name": "Zhi-Rong Yang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Qun Sun",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            }
        ],
        "venue": "Biochemical genetics",
        "year": 2007
    },
    "BSBtCGxF": {
        "id": "BSBtCGxF",
        "title": "Agrobacterium-mediated genetic transformation of Elymus breviaristatus with Pseudomonas pseudoalcaligenes insecticidal protein gene",
        "abstract": "An efficient and repeatable protocol for generating transgenic Elymus breviaristatus plants was first established by Agrobacterium-mediated transformation: calli of Elymus breviaristatus were induced from mature seeds, and proliferated on callus induction and maintenance medium containing kinetin 0.05 mg/l and 2, 4-D 8.0 mg/l under dim-light condition (10-20 μmol/m 2s,16 h light) at 26°C. The calli produced were used for transformation mediated by Agrobacterium tumefaciens, EHA105, which carries the binary vector pCAMBIA 1304-ppip, coding for the Pseudomonas pseudoalcaligenes insecticidal protein gene (ppip) and hygromycin phosphotransferase II gene (hptII). The calli transformed were selected and grown in the presence of 60 mg/l hygromycin. Approximately 90 transgenic plants were produced, and transformation frequency of the calli reached 10.52%. The presence of ppip gene in the genomic DNA of regenerated plants was detected by means of PCR and Southern-blot analysis, and the expression of the transgenes was verified by reverse transcription-PCR. Approximately 90% of the tested plants appeared to have only one or two copies of the T-DNA inserts. Verification of anti-grasshoppers activity shows the mortality of grasshoppers reached 16.73%. These results indicated that Agrobacterium-mediated transformation in our condition was effective for transferring foreign genes into Elymus breviaristatus. © 2007 Springer Science+Business Media B.V.",
        "keywords": [
            "agrobacterium-mediated transformation",
            "callus regeneration",
            "mature embryo",
            "ppip gene",
            "transgenic plant",
            "genomic dna",
            "genetic transformation",
            "reverse transcription pcr",
            "embryos"
        ],
        "authors": [
            {
                "name": "Daxu X. Li",
                "org": "Sichuan Grassland Science Academy(Sichuan Grassland Science Academy,Sichuan Academy of Grassland Science),Chengdu,China"
            },
            {
                "name": "Qun Sun",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Min Huang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Shiqie Bai",
                "org": "Sichuan Grassland Science Academy(Sichuan Grassland Science Academy,Sichuan Academy of Grassland Science),Chengdu,China"
            },
            {
                "name": "Linyong Zheng",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Jian Zhao",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "DunLian Qiu",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Lì Lì",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "ZhiRong Yang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Minghong You",
                "org": "Sichuan Grassland Science Academy(Sichuan Grassland Science Academy,Sichuan Academy of Grassland Science),Chengdu,China"
            },
            {
                "name": "Gang Liu",
                "org": "Sichuan Grassland Science Academy(Sichuan Grassland Science Academy,Sichuan Academy of Grassland Science),Chengdu,China"
            },
            {
                "name": "Yu Zhang",
                "org": "Sichuan Grassland Science Academy(Sichuan Grassland Science Academy,Sichuan Academy of Grassland Science),Chengdu,China"
            },
            {
                "name": "Changbing Zhang",
                "org": "Sichuan Grassland Science Academy(Sichuan Grassland Science Academy,Sichuan Academy of Grassland Science),Chengdu,China"
            },
            {
                "name": "Shaocai Li",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            }
        ],
        "venue": "Plant Cell, Tissue and Organ Culture",
        "year": 2007
    },
    "Csj1vMAX": {
        "id": "Csj1vMAX",
        "title": "<i>Agrobacterium</i>–mediated genetic transformation of <i>Elymus breviaristatus</i> with <i>Pseudomonas pseudoalcaligenes</i> insecticidal protein gene",
        "abstract": "An efficient and repeatable protocol for generating transgenic Elymus breviaristatus plants was first established by Agrobacterium-mediated transformation: calli of Elymus breviaristatus were induced from mature seeds, and proliferated on callus induction and maintenance medium containing kinetin 0.05 mg/l\n and 2, 4-D 8.0 mg/l under dim-light condition (10–20 μmol/m2s,16 h light) at 26°C. The calli produced were used for transformation mediated by Agrobacterium tumefaciens, EHA105, which carries the binary vector pCAMBIA 1304-ppip, coding for the Pseudomonas pseudoalcaligenes insecticidal protein gene (ppip) and hygromycin phosphotransferase II gene (hptII). The calli transformed were selected and grown in the presence of 60 mg/l hygromycin. Approximately 90 transgenic plants\n were produced, and transformation frequency of the calli reached 10.52%. The presence of ppip gene in the genomic DNA of regenerated plants was detected by means of PCR and Southern-blot analysis, and the expression\n of the transgenes was verified by reverse transcription-PCR. Approximately 90% of the tested plants appeared to have only\n one or two copies of the T-DNA inserts. Verification of anti-grasshoppers activity shows the mortality of grasshoppers reached\n 16.73%. These results indicated that Agrobacterium-mediated transformation in our condition was effective for transferring foreign genes into Elymus breviaristatus.",
        "keywords": [
            "breviaristatus. keywords agrobacterium-mediated transformationcallus regenerationmature embryo � ppip genetransgenic plant"
        ],
        "authors": [
            {
                "name": "Daxu Li",
                "org": "Sichuan Academy of Grassland Science, 611731 Chengdu, P.R. China"
            },
            {
                "name": "Qun Sun",
                "org": "College of Life Sciences, Key Laboratory of Bio-resources and Eco-environment, The Ministry of Education, Sichuan University, 610064 Chengdu, P.R. China"
            },
            {
                "name": "Min Huang",
                "org": "College of Life Sciences, Key Laboratory of Bio-resources and Eco-environment, The Ministry of Education, Sichuan University, 610064 Chengdu, P.R. China"
            },
            {
                "name": "Jie Zhang",
                "org": "College of Life Sciences, Key Laboratory of Bio-resources and Eco-environment, The Ministry of Education, Sichuan University, 610064 Chengdu, P.R. China"
            },
            {
                "name": "Shiqie Bai",
                "org": "Sichuan Academy of Grassland Science, 611731 Chengdu, P.R. China"
            },
            {
                "name": "Linyong Zheng",
                "org": "College of Life Sciences, Key Laboratory of Bio-resources and Eco-environment, The Ministry of Education, Sichuan University, 610064 Chengdu, P.R. China"
            },
            {
                "name": "Jian Zhao",
                "org": "College of Life Sciences, Key Laboratory of Bio-resources and Eco-environment, The Ministry of Education, Sichuan University, 610064 Chengdu, P.R. China"
            },
            {
                "name": "Dunlian Qiu",
                "org": "College of Life Sciences, Key Laboratory of Bio-resources and Eco-environment, The Ministry of Education, Sichuan University, 610064 Chengdu, P.R. China"
            },
            {
                "name": "Li Li",
                "org": "College of Life Sciences, Key Laboratory of Bio-resources and Eco-environment, The Ministry of Education, Sichuan University, 610064 Chengdu, P.R. China"
            },
            {
                "name": "Zhirong Yang",
                "org": "College of Life Sciences, Key Laboratory of Bio-resources and Eco-environment, The Ministry of Education, Sichuan University, 610064 Chengdu, P.R. China"
            },
            {
                "name": "Minghong You",
                "org": "Sichuan Academy of Grassland Science, 611731 Chengdu, P.R. China"
            },
            {
                "name": "Gang Liu",
                "org": "Sichuan Academy of Grassland Science, 611731 Chengdu, P.R. China"
            },
            {
                "name": "Yu Zhang",
                "org": "Sichuan Academy of Grassland Science, 611731 Chengdu, P.R. China"
            },
            {
                "name": "Changbing Zhang",
                "org": "Sichuan Academy of Grassland Science, 611731 Chengdu, P.R. China"
            },
            {
                "name": "Shaocai Li",
                "org": "College of Life Sciences, Key Laboratory of Bio-resources and Eco-environment, The Ministry of Education, Sichuan University, 610064 Chengdu, P.R. China"
            }
        ],
        "venue": "Plant Cell Tissue and Organ Culture",
        "year": 2007
    },
    "Ye1SAgAO": {
        "id": "Ye1SAgAO",
        "title": "Community of extremely halophilic bacteria in historic Dagong Brine Well in southwestern China",
        "abstract": "The Dagong Brine Well, the earliest man-made brine well in record, located in Zigong, Sichuan, China, had the construction\n and facilities mainly made of bamboo, wood and stone that are eroded easily by halophiles colonizing in the brine of the well.\n To better preserve this historic placemark, we initiated an investigation on the microbial community and the diversity of\n the halophilic bacteria in the brine of Dagong well for the first time. A total of 112 aerobic halophile strains were isolated\n and characterized according to their phenotype, cellular fatty acids composition and 16S rRNA. Furthermore, the intra specific\n phylogeny of closely related strains was also screened by PCR fragment length polymorphism of 16S–23S ribosomal RNA intergenic\n spacer regions (ISR). The result showed that the halophilic isolates found in current study were closely related to the following\n genera: Planococcus, Halomonas, Halobacillus, Oceanobacillus and Virgibacillus, a lineage of the domain Bacteria. Halomonas and Halobacillus were the dominant genera as represents 27% and 40% of the total isolates, respectively. The distribution of other genera\n was as follows: Oceanobacillus (18%), Virgibacillus (10%) and Planococcus (5%). The ISR analysis disclosed variation of banding pattern in some isolates related to Oceanobacillus and Halobacillus which was observed with phenotypic and physiological characterizations as well. It was clear that these halophiles have adapted\n to the special man-made hypersaline environment by the basic physiological evolution during phylogenesis and thus resulted\n in phenotypic and genotypic diversity in the Dagong Brine Well.",
        "keywords": [
            "16s-23s rrna isr � 16s rrna � dagong brine wellextremely halophilic bacteria � microbial diversity",
            "polymorphism",
            "ribosomal rna",
            "microbial community"
        ],
        "authors": [
            {
                "name": "Wenliang Xiang",
                "org": "Sichuan University College of Life Sciences, Key Laboratory of Bio-resource and Bio-control Chengdu Sichuan 610064 People’s Republic of China"
            },
            {
                "name": "Jianhua Guo",
                "org": "Sichuan University College of Life Sciences, Key Laboratory of Bio-resource and Bio-control Chengdu Sichuan 610064 People’s Republic of China"
            },
            {
                "name": "Wei Feng",
                "org": "Sichuan University College of Life Sciences, Key Laboratory of Bio-resource and Bio-control Chengdu Sichuan 610064 People’s Republic of China"
            },
            {
                "name": "Min Huang",
                "org": "Sichuan University College of Life Sciences, Key Laboratory of Bio-resource and Bio-control Chengdu Sichuan 610064 People’s Republic of China"
            },
            {
                "name": "Hao Chen",
                "org": "Institute of Atomic Energy Chengdu Sichuan 610066 People’s Republic of China"
            },
            {
                "name": "Jian Zhao",
                "org": "Sichuan University College of Life Sciences, Key Laboratory of Bio-resource and Bio-control Chengdu Sichuan 610064 People’s Republic of China"
            },
            {
                "name": "Jie Zhang",
                "org": "Sichuan University College of Life Sciences, Key Laboratory of Bio-resource and Bio-control Chengdu Sichuan 610064 People’s Republic of China"
            },
            {
                "name": "Zhirong Yang",
                "org": "Sichuan University College of Life Sciences, Key Laboratory of Bio-resource and Bio-control Chengdu Sichuan 610064 People’s Republic of China"
            },
            {
                "name": "Qun Sun",
                "org": "Sichuan University College of Life Sciences, Key Laboratory of Bio-resource and Bio-control Chengdu Sichuan 610064 People’s Republic of China"
            }
        ],
        "venue": "World Journal of Microbiology & Biotechnology",
        "year": 2008
    },
    "UX8vAdvq": {
        "id": "UX8vAdvq",
        "title": "Molecular Characterization of Drug-Resistant Mycobacterium tuberculosis Isolates from Sichuan Province in China",
        "abstract": "SUMMARY: Tuberculosis is still a severe public health issue in eastern Asia, and Sichuan is the key area for tuberculosis control in China. To determine the phenotypic and mutation patterns of drug resistance in Myco- bacterium tuberculosis isolates from Sichuan, the drug susceptibility of 198 clinical isolates was examined. Among these isolates, 76 drug-resistant and 20 susceptible isolates were analyzed for the rpoB, embB, and katG and inhA regulatory regions. These are the mutations believed to associate with rifampin (RIF), ethambutol (EMB), and isoniazid (INH) resistance, respectively. Of the 60 RIF-resistant isolates, 54 (90.0%) carried muta- tions on the amplified fragment of the rpoB gene, and the most common one (64.8%, 35/54) was at codon 531. Two new mutation patterns were recognized: one isolate harbored three mutations at codons 511, 516, and 518, and the other carried the dual mutation GAC↑ACC at codon 516. A total of 30 INH-resistant isolates (60.0%, 30/50) had mutations at codon 315, whereas 4 (8.0%) had mutations at the inhA regulatory region. Among the 46 EMB-resistant isolates, 22 harbored the Met306 mutation. The results showed geographical variation in the mutation types of drug-resistant genes in M. tuberculosis isolates from Sichuan; this finding is valuable for the development of targeted and rapid molecular diagnostic methods suitable for specific regions.",
        "keywords": [],
        "authors": [
            {
                "name": "Jian-Hua Guo",
                "org": "College of Life Sciences|Sichuan University|College of Bioengineer|Xihua University"
            },
            {
                "name": "Wen-Liang Xiang",
                "org": "College of Life Sciences|Sichuan University|College of Bioengineer|Xihua University"
            },
            {
                "name": "Qing-Rong Zhao",
                "org": "Chengdu Antituberculosis Hospital"
            },
            {
                "name": "Tao Luo",
                "org": "Chengdu Antituberculosis Hospital"
            },
            {
                "name": "Min Huang",
                "org": "College of Life Sciences|Sichuan University|College of Bioengineer|Xihua University"
            },
            {
                "name": "Jie Zhang",
                "org": "College of Life Sciences|Sichuan University|College of Bioengineer|Xihua University"
            },
            {
                "name": "Jian Zhao",
                "org": "College of Life Sciences|Sichuan University|College of Bioengineer|Xihua University"
            },
            {
                "name": "Zhi-Rong Yang",
                "org": "College of Life Sciences|Sichuan University|College of Bioengineer|Xihua University"
            },
            {
                "name": "Qun Sun",
                "org": "College of Life Sciences|Sichuan University|College of Bioengineer|Xihua University"
            }
        ],
        "venue": "Japanese Journal of Infectious Diseases",
        "year": 2008
    },
    "rOYapzcx": {
        "id": "rOYapzcx",
        "title": "Cloning of the gene encoding an insecticidal protein in pseudomonas pseudoalcaligenes",
        "abstract": "Pseudomonas pseudoalcaligenes strain PPA (first isolated from yellow-spined bamboo locust, Ceracris kiangsu, in 1991) is an effective biological control agent for locust. Escherichia coli DH5á was transformed using a partial Sau3AI digest of P. pseudoalcaligenes chromosomal DNA ligated with pUC19 vector cut by BamHI. The resulting genomic library was screened using an oligodeoxynucleotide probe derived from the N-terminal sequence of the purified insecticidal protein. Five positive clones were obtained after two rounds of screening. The 1.4 kb BamHI-KpnI fragment of the smallest clone (pSC1) contained the N terminal sequence of the insecticidal protein. Further sequencing identified an open reading frame encoding a polypeptide of 276 amino acid residues that is thought to contain a signal peptide of 22 amino acids and a mature protein of 254 amino acids. The calculated molecular weight of 26.7 kDa for the putative mature protein is close to that of the native insecticidal protein. The insecticidal protein lacked significant identity with toxic proteins from other bacteria upon comparison of amino acid sequences. A BamHI-KpnI fragment was cloned into pT7-6. A novel protein was expressed in E. coli BL21 (DE3) and its western blot similar to natural toxin.",
        "keywords": [
            "gene cloning",
            "insecticidal protein",
            "locust",
            "pseudomonas pseudoalcaligenes",
            "dna sequencing",
            "dna cloning",
            "open reading frames",
            "genes",
            "amino acid",
            "biological control",
            "n terminal",
            "signal peptide",
            "molecular weight",
            "open reading frame",
            "escherichia coli",
            "amino acid sequence",
            "genomic library"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Jian Zhao",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Daxu X. Li",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Sujun Liu",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Lì Lì",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Qun Sun",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Ming Huang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "ZhiRong Yang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            }
        ],
        "venue": "Annals of Microbiology",
        "year": 2009
    },
    "CZkx6hNj": {
        "id": "CZkx6hNj",
        "title": "Effect of the untranslated region and signal peptide sequence of the insecticidal gene from Pseudomonas pseudoalcaligenes on the activity of its expression products in tobacco",
        "abstract": "The 3′ untranslated region (3′UTR) and the signal peptide sequence (SPS) are important factors affecting protein transcription and translation. To investigate the effect of the 3′UTR and SPS on the activity of expression products of Pseudomonas pseudoalcaligenes insecticidal protein gene (ppip), the ppip constructs containing 3′UTR or SPS were cloned by PCR and then transformed into tobacco. The insecticidal proteins obtained in the different ppip-transformed tobacco strains were analyzed by SDS-PAGE and verified by Western blot analysis. The insecticidal activity of crude proteins expressed by different ppip constructs was determined by calculating the average mortality of larvae. Crude protein expressed by ppip with the SPS caused mean mortality of second and third instar larvae of 18.34% whereas for those without the SPS mean mortality was 71.67%. Constructs containing the 3′UTR had no significant effect on the mortality of larvae. This first report about the effect of 3′UTR and SPS on the ppip product is helpful for effective genetic engineering of insecticidal plants. © 2008 Springer Science+Business Media B.V.",
        "keywords": [
            "insecticidal activity",
            "pseudomonas pseudoalcaligenes insecticidal protein gene",
            "signal peptide sequence",
            "tobacco transformation",
            "untranslated region",
            "Insecticidal activity",
            "Pseudomonas pseudoalcaligenes insecticidal protein gene",
            "Signal peptide sequence",
            "Tobacco transformation",
            "Untranslated region"
        ],
        "authors": [
            {
                "name": "Min Huang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Daxu X. Li",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Wen-Liang Xiang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Hao Chen",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Jian-Hua Guo",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Jian Zhao",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Zhi-Rong Yang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Qun Sun",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            }
        ],
        "venue": "World Journal of Microbiology and Biotechnology",
        "year": 2009
    },
    "sesPm1k7": {
        "id": "sesPm1k7",
        "title": "Structure characterization of polysaccharide isolated from the fruiting bodies of Tricholoma matsutake",
        "abstract": "A novel heteropolysaccharide was isolated from the fruiting bodies of Tricholoma matsutake through DEAE–cellulose column and Sephadex G-100 column. The T. matsutake polysaccharide (TMP-A) had a molecular weight of 8.89 × 10 4 Da and was mainly composed of 4-D-Glc:4,6-D-Glc:3-D-Gal:T-D-Xyl and with the ratio of 7:1:1:1. The structural features of TMP-A were investigated by a combination of total hydrolysis, methylation analysis, gas chromatography–mass spectrometry (GC–MS), scanning electron microscope (SEM), infrared (IR) spectra, nuclear magnetic resonance (NMR) spectroscopy and dynamical analysis of the atomic force microscope (AFM) studies. The results indicated that TMP-A had a backbone of 1,4-β-glucopyranos which branches at O-6 composed of an (1 → 3)-α-galactopyranose residue and terminated with α-xylopyranose residue. Chain conformation study showed that the polysaccharide took random coil compact conformation. Keywords Monosaccharide component Polysaccharide structure GC–MS 13 C and 1 H NMR Tricholoma matsutake 1 Introduction Oxidation is essential to many organisms for the production of energy to fuel biological processes. However, the uncontrolled production of superoxide anion free radicals is involved in onset of many diseases such as cancer, atherosclerosis and degenerative processes ( Mau, Tsai, Tseng, & Huang, 2005 ). Plant polysaccharides have shown strong antioxidant properties and can be used as a novel potential antioxidant ( Hu, Xu, & Hu, 2003; Ramarahnam, Osawa, Ochi, & Kawaishi, 1995; Wang & Luo, 2007 ). In addition, polysaccharides extracted from mushrooms, such as Lentinus edodes , Ganoderma tsugae and Cordyceps sinensis , have also exhibited antioxidant properties by their free radical scavenging ability ( Chen, Xie, Nie, Li, & Wang, 2008; Chen, Zhong, Zeng, & Ge, 2008; Dong & Yao, 2008; Tseng, Yang, & Mau, 2008; Yu, Yin, Yang, & Liu, 2008 ). Such natural antioxidants may be effective to protect humans from free radicals damage and many chronic diseases ( Kinsella, Frankel, German, & Kanner, 1993 ). Tricholoma matsutake is a kind of fungi belonging to Subgenus Tricholoma . As a traditional edible fungus in oriental countries, it has been used for the prevention and treatment of diseases for several thousand years ( Gong, Su, Chen, Feng, & Cao, 2002; Gurein et al., 2003; Hur, Park, Kang, & Joo, 2004 ). As an extract from the fruiting bodies of T. matsutake , polysaccharides (TMP) have shown strong anti-tumor bioactive properties ( Gao, 1997; Liu, 2001; Mikio et al., 1999; Shung, 2004 ). The determination of the structure of polysaccharides is necessary to establish a fundamental guide for assessing the bioactivity and pharmacological mechanism in vivo/in vitro. In this work, we reported a novel water-soluble polysaccharide was extracted and purified from the fruiting bodies of T. matsutake using a DEAE-cellulose column chromatography and a Sephadex G-100 column chromatography. Its chemical structures were further characterized and our results provided a basis for future pharmacological studies. 2 Materials and methods 2.1 Chemicals The fruiting bodies of T. matsutake were collected in Xiaojing country of Sichuan province, China, and were authenticated by Prof Sao-rong Ge (College of Life Sciences, Sichuan University, Chengdu, China). At the same time, a voucher specimen had been preserved in Key Laboratory for Biological Resource and Ecological Environment of Education Ministry, College of Life Sciences, Sichuan University. DEAE-Cellulose 52 and Sephadex G-100 were purchased from Sigma–Aldrich (Mainland, China). Monosaccharide standards, Dextran T-500, T-110, T-70, T-40, and T-10, were purchased from Beijing Biodee Biotechnology Co., Ltd. (Beijing, China). All other reagents used were of analytical grade. 2.2 Extraction of polysaccharides from T. matsutake The fruiting bodies (200 g) of T. matsutake were soaked with 95% EtOH for 6 h to remove lipids by filtration. Then the residue was dried and extracted with boiling water for three times (6 h for each). The filtrate was concentrated, dialyzed (MWCO 5000, Sigma), and centrifuged to remove insoluble material and small molecular compounds. Then the supernatant was added with 3 volumes of 95% EtOH to precipitate crude polysaccharides. The precipitate was recovered by centrifugation and washed successively with absolute EtOH, followed by drying in vacuo at 45 °C, yielding the crude T. matsutake polysaccharide (TMP) (32.8 g, recovery 16.4%). Sevag method ( Staub, 1965 ) was used for the deproteination of TMP, 30% H 2 O 2 for decoloration, respectively. 2.3 Purity and fractionation of polysaccharides The resulting polysaccharide solution was dialyzed, concentrated and lyophilized. TMP (8 g) was subjected to a DEAE–cellulose column (Tris–HCl, pH 7.0, 4.5 cm × 50 cm, Cl − ) and eluted stepwise with 0, 0.1, 0.2, 0.3, 0.4, 0.5 and 1.0 M NaCl. The eluate was monitored by the phenol–sulfuric acid method ( Dubois, Gillis, Hamilton, Rebers, & Smith, 1956 ). The 0 M NaCl eluation was concentrated, dialyzed, and lyophilized. Then the resulting polysaccharide was purified on a Sephadex G-100 column (2.6 cm × 60 cm) and eluted with 0 M NaCl. The resulting T. matsutake polysaccharide, named TMP-A, was obtained by the above processes and the yield rate of TMP-A was 0.22% (0.432 g) for the starting material. 2.4 Measurement of molecular weight of TMP-A High performance gel permeation chromatography (HPGPC) was carried out to measure molecular weight. The column was calibrated with standard T-series Dextran (T-500, T-110, T-70, T-40 and T-10). The data were processed with Waters GPC (Millennium32 software). 2.5 Monosaccharide composition analysis The polysaccharide TMP-A (5.0 mg) was hydrolyzed with 2 M trifluoroacetic acid at 110 °C for 6 h on the mechanism of acid-catalyzed hydrolysis ( Nelson & Cox, 2004; Yu et al., 2009 ). Excess acid was removed by co-distillation with Methanol after the hydrolysis was completed. One part of the hydrolysate (1.0 mg) was used for thin layer chromatography analysis as described previously ( Liu, Dong, & Fang, 2001; Partridge, 1949; Zhang, 1999 ), and the other (1.0 mg) was dissolved in pyridine (0.2 mL). The derivatization reaction was initiated by addition of hexamethyl-disilazane (0.2 mL) and trimethyl chloro-silicane (0.2 mL) according to the method described by Dong, Zhang, Lin, and Fang (1995) and Guentas et al. (2001) . The resulting supernatant was examined by GC–MS at a temperature program of 50–230 °C with a rate of 2 °C/min ( Chen, Xie, et al., 2008; Chen, Zhong, et al., 2008; Needs & Selvendran, 1993 ). 2.6 Methylation analysis The polysaccharide, TMP-A (10 mg), was methylated according to the Hakomori method ( Hakomori, 1964 ). After being methylated completely, the permethylated polysaccharide was depolymerized with 90% aqueous formic acid (3 mL) for 10 h at 100 °C in a sealed tube. The methylated sugars were derivatized using the method described by Dong et al. (1995) and analyzed by GC–MS. 2.7 UV and infrared (IR) spectra analysis TMP-A was tested in UV from 200 nm to 600 nm. And Infrared analysis of the samples was obtained by grinding a mixture of polysaccharide with dry KBr and then pressing in a mold. Spectra were run in the 4000–400 cm −1 region ( Kumar, Joo, Choi, Koo, & Chang, 2004 ). 2.8 Nuclear magnetic resonance (NMR) experiment 1 H NMR spectra and 13 C NMR spectra were recorded on a Varian Unity INOVA 400/45 in D 2 O with tetramethylsilane as internal standard. 2.9 Atomic force micrograph (AFM) The normal sample preparation procedure consisted of spreading of a dilute (25 μg/mL) polymer solution onto a freshly cleaved mica surface and successive air-drying under ambient pressure, temperature, and humidity ( Kirby, Gunning, & Morris, 1995; Michela, Meredith, Paola, Neil, & Rizzo, 2009 ). The atomic force microscopy was operated in the tapping-mode ( Gunning et al., 2003; Morri, Gunning, Kirby, Round, & Waldron, 1997 ). 3 Results and discussion 3.1 Extraction, purity and composition of polysaccharides The crude polysaccharide, named TMP, was obtained from the fruiting bodies of T. matsutake with a yield of 16.4%. After fractionation on DEAE-Cellulose 52 and Sephadex G-100 column chromatography, 432 mg of TMP-A was obtained from the 0 M NaCl eluate and detected by the phenol–sulfuric acid assay ( Dubois et al., 1956 ). The homogeneity of the polysaccharide was elucidated by the following tests: TMP-A was eluted from gel-filtration chromatography on Sephadex G-100 column and was also detected by the phenol–sulfuric acid assay as a single peak ( Fig. 1 ). The amber-coloured crystal TMP-A were shown by SEM in Fig. 2 . No absorption at 280 nm and 260 nm in UV absorption spectra of TMP-A demonstrated the absence of protein and nucleic acid in this polysaccharide and it had the same optical rotation: [ α ] D 20 – 1.648° (c0.5, water), in different low concentration of ethanol using HK7-SGW-1 automatic optical polarimeter at room temperature. Weight-average molecular weight was around 8.89 × 10 4 Da. The Rf values of hydrolyzed sample monosaccharide using TLC were 0.272, 0.538, 0.156, respectively, which were the same as the standard monosaccharide (Glucose, Galactose, Xylose). The color of monosaccharides (Glc, Gal) were shown clearly as blue and Xyl as brown-green. The three monosaccharides, D-Glc, D-Xyl and D-Gal were also identified using the hydrolysate of TMP-A by GC–MS and their ratios were 8:1:1. TMP-A was supposed to contain the D-configuration monosaccharide according to GC–MS analysis. 3.2 Structure elucidation of TMP-A The intensity of bands around 3408.22 cm −1 in the IR spectrum ( Fig. 3 ) was due to the hydroxyl stretching vibration of the polysaccharide and as expected they were broad. The bands in the region of 2923.62 cm −1 were due to C–H stretching vibration and the bands in the region of 1643.29 cm −1 were due to associated water ( Cao et al., 2006; Park, 1971 ). Two strong absorption bands at 1075.03 cm −1 , 1041.64 cm −1 in the range of 1200–1000 cm −1 suggested that the monosaccharide of TMP-A had a pyrnaose-ring ( Barker, Bourne, Stacey, & Whiffen, 1954; Cui et al., 2008 ) ( Fig. 3 ). The absorption at 875.43 cm −1 indicated that TMP-A had β-glycopyranosidic linkages, which was also indicated by the anomeric proton signals at δ 4.660 in the 1 H NMR (400 MHz) ( Chakraborty, Mondal, Pramanik, Rout, & Islam, 2004; Kim et al., 2000 ). Moreover, the characteristic absorptions at 799.73 cm −1 indicated α-configurations existing in the polysaccharide ( Wu & Tu, 2005 ), which was in good agreement with the anomeric proton signals at δ 5.263, δ 5.182 and δ 5.107 in the 1 H NMR (400 MHz) spectrum. The resonances in the region of 98–106 ppm in the 13 C NMR (200 MHz) spectrum of TMP-A were attributed to the anomeric carbon atoms of glucopyranose (Glc p ), galactopyranose (Gal p ) and xylopyranose (Xyl p ) ( Wang, Liang, & Zhang, 2001; Wang, Luo, & Liang, 2004; Zhao, Kan, Li, & Chen, 2005 ). In the anomeric carbon region, signals at δ 105.2 could be attributed to C-1 of →4)-β-D-Glc p -(1→; δ 105.4 to C-1 of →4,6)-β-D-Glc p -(1→; δ 100.7 to C-1 of →3)-α-D-Gal p -(1→; δ 104.1 to C-1 of α.-D-Xyl p -(1→, respectively ( Fig. 4 ). All the assignment of the carbon atoms signals was shown in Table 1 . After methylation by the modified method ( Hakomori, 1964 ) for four times, the methylated polysaccharide was depolymerized and converted into partially methylated ramifications. The analysis of the methylated monosaccharide was conducted by GC–MS. The information in MS showed that fragment ion peaks were consistent with data of D-configuration monosaccharide fragment ions peaks which can be concluded that the glucose, galactose and xylose residues were D configuration. Methylation analysis for TMP-A proved that the glucose residues were 2,3-bis-substituted and 2,3,6-tri-subsituted, respectively, the galactose residues were 2,4,6-tri-subsituted, and the xylose residue was 2,3,4-tri-subsituted (see Table 2 and Fig. 5 ). Both results of monosaccharide composition analysis and methylated linkage analysis of TMP-A indicated that (1 → 4)-linked-glucose was the largest amounts residue of the polysaccharide structure, and the branched residue was (1 → 4,6)-linked-glucose revealing that (1 → 4)-linked-glucose should be possible to form the backbone structure. The relative amounts of (1 → 4,6)-linked-glucose indicated that approximate branch ratios could theoretically be 12.5%, namely on average one branching point for each eight residues of backbone. Residues of branch structure were (1 → 3)-linked-galactose and terminated with α-xylopyranose residue, which also get from those data of monosaccharide composition analysis and methylated linkage analysis. It is concluded that a repeating unit of TMP-A has a backbone of (1 → 4)-β- d -glucose residues which branches at O-6 based and the branch was supposed to be the composition of an (1 → 3)-α- d -galactose residue and one terminated with α- d -xylose residue. The predicted structure of the novel polysaccharide TMP-A was shown in Fig. 5 . The topographical AFM planar image of TMP-A deposited from a 25 μg/mL water solution was shown in Fig. 6 a . Only spherical lumps can be seen which was in good agreement with the measurement performed by SEM ( Fig. 2 b) and the diameter and height of the lumps ranged from 20 nm to 56 nm ( Fig. 6 a). The heights of the spherical structures were much higher than that of a single polysaccharide chain (about 0.1–1 nm), suggesting that molecular aggregation was involved ( Fig. 6 b). We can see that irregularly shaped large structures were formed together like worm from AFM cubic image of TMP-A ( Fig. 6 b), which suggested that TMP-A could take random coil compact conformation. The conformation might be related to its side chains ( Marit, Gjertrud, Pawel, Berit, & Bjϕrn, 2003; Wang et al., 2010 ). 4 Conclusions According to the results above, it was concluded that the highly purified novel polysaccharide obtained from T. matsutake is a heteropolysaccharide namely TMP-A. The present study also showed that TMP-A consisted of three monosaccharides, namely D-Glc, D-Xyl and D-Gal and their ratios were 8:1:1 by GC–MS. Structure study demonstrated that TMP-A had a backbone of (1 → 4)-β-glucopyranose residues which branches at O-6 and the branches were composed of an (1 → 3)-α-galactopyranose residue and terminated with α-xylopyranose residue. Chain conformation study showed that the polysaccharide took random coil compact conformation. Further work is necessary to reveal detailed pharmacological effects of TMP-A including antioxidant, anticancer properties and degenerative processes with aging, etc. Acknowledgements The authors thank Pr. Pu Su (Department of Chemistry of Medicinal Natural Products and Key Laboratory of Drug Targeting of Education Ministry PRC, West China College of Pharmacy, Sichuan University) for helpful assistance in NMR experiments. This project was supported by Chinese National Programs of High Technology Research and Development ( 2007AA021506 ) and the 11th Five Years Key Programs for Science and Technology Development of China ( 2007BAD81B04 ). References Barker et al., 1954 S.A. Barker E.J. Bourne M. Stacey D.H. Whiffen Infra-red spectra of carbohydrates. Part I. Some derivatives of D-glucopyranose Journal of the Chemical Society – Chemical Communications 1954 171 176 Cao et al., 2006 W. Cao X.Q. Li L. Liu M.C. Wang H.T. Fan C. Li Structural analysis of water-soluble glucans from the root of Angelica sinensis (Oliv.) diels Carbohydrate Research 341 2006 1870 1877 Chakraborty et al., 2004 I. Chakraborty S. Mondal M. Pramanik D. Rout S.S. 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Zhang Studies on the structure of JS1 – The water soluble polysaccharide isolated by alkaline from Hippophae rhamnoides L Chemical Journal of Chinese University 22 2001 1688 1690 Wang et al., 2004 Z.J. Wang D.H. Luo Z.Y. Liang Structure of polysaccharides from the fruiting body of Hericium erinaceus Pers Carbohydrate Polymers 57 2004 241 247 Wang and Luo, 2007 Z.J. Wang D.H. Luo Antioxidant activities of different fractions of polysaccharide purified from Gynostemma pentaphyllum Makino Carbohydrate Polymers 68 2007 54 58 Wang et al., 2010 Y.F. Wang Y.H. Peng X.L. Wei Z.W. Yang J.B. Xiao Z.Y. Jin Sulfation of tea polysaccharides: Synthesis, characterization and hypoglycemic activity International Journal of Biological Macromolecules 46 2010 270 274 Wu and Tu, 2005 X.M. Wu P.F. Tu Isolation and characterization of a-(1→6)-glucans from Cistanche deserticola Journal of Asian Natural Products Research 7 2005 823 828 Yu et al., 2008 Z.H. Yu L.H. Yin Q. Yang Y. Liu Effect of Lentinus edodes polysaccharide on oxidative stress,immunity activity and oral ulceration of rats stimulated by phenol Carbohydrate Polymers 10 2008 1016 1020 Yu et al., 2009 R.M. Yu Y. Yin W. Yang W.L. Ma L. Yang X.J. Chen Structural elucidation and biological activity of a novel polysaccharide by alkaline extraction from cultured Cordyceps militaris Carbohydrate Polymers 75 2009 166 171 Zhang, 1999 W.J. Zhang Technology of biochemical research on polysaccharides 1999 Zhejiang University Press Hangzhou pp. 35–40 Zhao et al., 2005 G.H. Zhao J.Q. Kan Z.X. Li Z.D. Chen Structural features and immunological activity of a polysaccharide from Dioscorea opposita Thunb roots Carbohydrate Polymers 61 2005 125 131",
        "keywords": [
            "13c and 1h nmr",
            "gc-ms",
            "monosaccharide component",
            "polysaccharide structure",
            "tricholoma matsutake",
            "ir spectra",
            "gas chromatography mass spectrometry",
            "nmr spectroscopy",
            "atomic force microscope",
            "gc ms",
            "scanning electron microscope",
            "nuclear magnetic resonance",
            "molecular weight",
            "dynamic analysis",
            "infrared"
        ],
        "authors": [
            {
                "name": "Xiang Ding",
                "org": ""
            },
            {
                "name": "Su Feng",
                "org": ""
            },
            {
                "name": "Mei Cao",
                "org": ""
            },
            {
                "name": "Mao-tao Li",
                "org": "Key Laboratory of Biological Resource and Ecological Environment of the Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610064, PR China"
            },
            {
                "name": "Jie Tang",
                "org": "Key Laboratory of Biological Resource and Ecological Environment of the Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610064, PR China"
            },
            {
                "name": "Chun-xiao Guo",
                "org": "Key Laboratory of Biological Resource and Ecological Environment of the Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610064, PR China"
            },
            {
                "name": "Jie Zhang",
                "org": "Key Laboratory of Biological Resource and Ecological Environment of the Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610064, PR China"
            },
            {
                "name": "Qun Sun",
                "org": "Key Laboratory of Biological Resource and Ecological Environment of the Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610064, PR China"
            },
            {
                "name": "Zhi-rong Yang",
                "org": "Key Laboratory of Biological Resource and Ecological Environment of the Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610064, PR China"
            },
            {
                "name": "Jian Zhao",
                "org": ""
            }
        ],
        "venue": "Carbohydrate Polymers",
        "year": 2010
    },
    "GtG82LCf": {
        "id": "GtG82LCf",
        "title": "Structure elucidation and antioxidant activity of a novel polysaccharide isolated from Tricholoma matsutake.",
        "abstract": "In this study, structural features of Tricholoma matsutake polysaccharide (TMP-A) were investigated by a combination of infrared (IR) spectra, gas chromatography-mass spectrometry (GC-MS), nuclear magnetic resonance (NMR) spectroscopy. The results indicated that TMP-A had a backbone of 1,4-beta-d-glucopyranose residue which branches at O-6 based on the experimental results. The branches were mainly composed of an (1-->3)-alpha-d-galactopyranose residue, and terminated with alpha-d-xylopyranose residue. The antioxidant activity of TMP-A was evaluated with several biochemical methods, including DPPH(-) radical scavenging, hydrogen peroxide scavenging, superoxide anion radical scavenging. The results indicated that TMP-A showed strong antioxidant. In the in vitro antioxidant assay by MTT method, TMP-A could attenuate PC12 cell damage significantly caused by hydrogen peroxide.",
        "keywords": [
            "antioxidant assay",
            "polysaccharide structure",
            "tricholoma matsutake",
            "hydrogen peroxide",
            "gas chromatography mass spectrometry",
            "ir spectra",
            "infrared",
            "nuclear magnetic resonance",
            "nmr spectroscopy",
            "structure elucidation"
        ],
        "authors": [
            {
                "name": "Xiang Ding",
                "org": ""
            },
            {
                "name": "Jie Tang",
                "org": ""
            },
            {
                "name": "Mei Cao",
                "org": ""
            },
            {
                "name": "Chun-Xiao Guo",
                "org": "Key Laboratory of Biological Resource and Ecological Environment of the Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610064, PR China"
            },
            {
                "name": "Xia Zhang",
                "org": "Key Laboratory of Biological Resource and Ecological Environment of the Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610064, PR China"
            },
            {
                "name": "Jing Zhong",
                "org": "Key Laboratory of Biological Resource and Ecological Environment of the Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610064, PR China"
            },
            {
                "name": "Jie Zhang",
                "org": "Key Laboratory of Biological Resource and Ecological Environment of the Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610064, PR China"
            },
            {
                "name": "Qun Sun",
                "org": "Key Laboratory of Biological Resource and Ecological Environment of the Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610064, PR China"
            },
            {
                "name": "Su Feng",
                "org": "Key Laboratory of Biological Resource and Ecological Environment of the Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610064, PR China"
            },
            {
                "name": "Zhi-Rong Yang",
                "org": "Key Laboratory of Biological Resource and Ecological Environment of the Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610064, PR China"
            },
            {
                "name": "Jian Zhao",
                "org": ""
            }
        ],
        "venue": "International journal of biological macromolecules",
        "year": 2010
    },
    "53X1VVUJ": {
        "id": "53X1VVUJ",
        "title": "Screening a novel Na+/H+ antiporter gene from a metagenomic library of halophiles colonizing in the Dagong Ancient Brine Well in China.",
        "abstract": "Metagenomic DNA libraries constructed from the Dagong Ancient Brine Well were screened for genes with Na(+)/H(+) antiporter activity on the antiporter-deficient Escherichia coli KNabc strain. One clone with a stable Na(+)-resistant phenotype was obtained and its Na(+)/H(+) antiporter gene was sequenced and designated as m-nha. The deduced amino acid sequence of M-Nha protein consists of 523 residues with a calculated molecular weight of 58 147 Da and a pI of 5.50, which is homologous with NhaH from Halobacillus dabanensis D-8(T) (92%) and Halobacillus aidingensis AD-6(T) (86%), and with Nhe2 from Bacillus sp. NRRL B-14911 (64%). It had a hydropathy profile with 10 putative transmembrane domains and a long carboxyl terminal hydrophilic tail of 140 amino acid residues, similar to Nhap from Synechocystis sp. and Aphanothece halophytica, as well as NhaG from Bacillus subtilis. The m-nha gene in the antiporter-negative mutant E. coli KNabc conferred resistance to Na(+) and the ability to grow under alkaline conditions. The difference in amino acid sequence and the putative secondary structure suggested that the m-nha isolated from the Dagong Ancient Brine Well in this study was a novel Na(+)/H(+) antiporter gene.",
        "keywords": [
            "dagong ancient brine well",
            "halophiles",
            "metagenomic library",
            "na+/h+ antiporter gene"
        ],
        "authors": [
            {
                "name": "Wenliang Xiang",
                "org": "Xihua University(Xihua University),Chengdu,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Lin Li",
                "org": "Xihua University(Xihua University),Chengdu,China"
            },
            {
                "name": "Huazhong Liang",
                "org": "Xihua University(Xihua University),Chengdu,China"
            },
            {
                "name": "Hai Luo",
                "org": "Xihua University(Xihua University),Chengdu,China"
            },
            {
                "name": "Jian Zhao",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Zhirong Yang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Qun Sun",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            }
        ],
        "venue": "FEMS microbiology letters",
        "year": 2010
    },
    "A9HD62ZL": {
        "id": "A9HD62ZL",
        "title": "Screening for bacteriocin-producing lactic acid bacteria from kurut, a traditional naturally-fermented yak milk from Qinghai–Tibet plateau",
        "abstract": "The objective of this study was to screen the bacteriocin-producing lactic acid bacteria (LAB) strains from kurut collected from six regions in Qinghai–Tibet Plateau. Upon the elimination of the effects of organic acids and hydrogen peroxide on tested microorganisms, 5 strains, among a total of 256 presumptive LAB strains screened, belonging to the species of Lactobacillus casei (strains T1, T11 and S9), Lactobacillus lactis (strain S2), and Leuconostoc lactis (strain T14), showed inhibition activities against both Staphylococcus aureus and Escherichia aerogenes . The inhibition activities were destroyed after treated with proteinase K, pepsin and trypsin separately, suggesting the proteinaceous nature of the antimicrobial compounds produced from the strains. The bacteriocins from strains T1 and T14 remained stable for 20 min at 121 °C and after 2 h of incubation at pH values between 3.0 and 11.0, compared with those from strains S2 and T11 that were stable during pH 3.0–6.0, and that from strain S9 stable between pH 3.0 and 9.0. Bacteriocins produced from strains S2, S9 and T11 were resistant to heating treatment at 100 °C for 20 min. Bacteriocins did not adhere to the surface of the producer cells. The results suggest that the extracellular bacteriocins produced from special LAB strains from kurut, of high antibacterial activity, as well as high thermal and pH stability, may be applied to dairy products manufactory to inhibit the growth of spoilage and pathogens during fermentation.",
        "keywords": [
            "hydrogen peroxide",
            "heat treatment"
        ],
        "authors": [
            {
                "name": "Fan Luo",
                "org": "College of Life Sciences & Technique, Southwest University for Nationalities, No. 16, South 4th Section 1st Ring Road, Chengdu, Sichuan 610061, P.R. China"
            },
            {
                "name": "Su Feng",
                "org": "College of Life Sciences, Sichuan University, 29 Wanjiang Rd., Chengdu, Sichuan 610064, P.R. China"
            },
            {
                "name": "Qun Sun",
                "org": "College of Life Sciences, Sichuan University, 29 Wanjiang Rd., Chengdu, Sichuan 610064, P.R. China"
            },
            {
                "name": "Wenliang Xiang",
                "org": "College of Bioengineering, XiHua University, 999 Jinzhou Rd., Chengdu, Sichuan 610039, P.R.China"
            },
            {
                "name": "Jian Zhao",
                "org": "College of Life Sciences, Sichuan University, 29 Wanjiang Rd., Chengdu, Sichuan 610064, P.R. China"
            },
            {
                "name": "Jie Zhang",
                "org": "College of Life Sciences, Sichuan University, 29 Wanjiang Rd., Chengdu, Sichuan 610064, P.R. China"
            },
            {
                "name": "Zhirong Yang",
                "org": ""
            }
        ],
        "venue": "Food Control",
        "year": 2011
    },
    "6uIl5lA7": {
        "id": "6uIl5lA7",
        "title": "Composition and antioxidant activity of water-soluble polysaccharides from Tuber indicum.",
        "abstract": "Crude water-soluble Chinese truffle Tuber indicum polysaccharide (TIP) was extracted from the fruiting bodies with water and then successively purified by DEAE-cellulose 52 and Sephadex G-100 column chromatography, yielding two major polysaccharide fractions: TIP1-1 and TIP2-1. High-performance gel permeation chromatography analysis showed that the average molecular sizes of TIP1-1 and TIP2-1 were approximately 1.75×10(4) Da and 5.73×10(3) Da, respectively. Monosaccharide component analysis by gas chromatography indicated that TIP1-1 was composed of mannose, glucose, galactose, and rhamannose in the respective molar ratio of 3.93:1.24:0.75:1.26 and that TIP2-1 contained mannose, glucose, and arabinose in the respective molar ratio of 5.27:1.44:0.43. The antioxidant activity analyses revealed that TIP1-1 and TIP2-1 possessed considerable antioxidant activity. Compared with TIP1-1, which has a higher molecular weight and contains no uronic acid, TIP2-1 exhibited a protective effect on PC12 cells injured by H(2)O(2) and a higher scavenging activity against free radicals. The relative effects of the lower molecular size, the presence of uronic acid, and the antioxidant activity of TIP2-1 appear to be significant. Accordingly, the Chinese truffle T. indicum might serve as an effective antioxidative healthcare food and source of natural antioxidants.",
        "keywords": [
            "antioxidant activity",
            "polysaccharide composition",
            "tuber indicum"
        ],
        "authors": [
            {
                "name": "Qiang Luo",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Liang Yan",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Yuanlin Tang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Xiang Ding",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Zhirong Yang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Qun Sun",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            }
        ],
        "venue": "Journal of medicinal food",
        "year": 2011
    },
    "jploTBIn": {
        "id": "jploTBIn",
        "title": "Purification and anticancer activity investigation of pentacyclic triterpenoids from the leaves of Sinojackia sarcocarpa L.Q. Luo by high-speed counter-current chromatography.",
        "abstract": "Sinojackia sarcocarpa L.Q. Luo has high aesthetic value, which is clinically used to treat diseases such as the variations of arthritis, thromboangiitis obliterans, angina pectoris as well as many other diseases. Pentacyclic triterpenoids are the main pharmacological effective compounds. High-speed counter-current chromatography method was performed on a Midi-DE centrifuge at 25°C. The solvent system was n-hexane-ethylacetate-methanol-water (10:5:3:1, v/v). Peak fractions were collected according to the elution profile for subsequent high-performance liquid chromatography analysis. The structure identification was performed by ultraviolet, infrared, mass spectrometry, (1)H-NMR and (13)C-NMR. Compound 2α,3α,19β,23β-tetrahydroxyurs-12-en-28-oic acid and 2α,3α,23β-trihydroxyurs-12-en-28-oic acid were purified from the plant of Styracaceaen genius for the first time, whose purities were 96.57% and 97.33%, respectively. Compared with the same dose of oral 5-fluorouracil with 57.6% inhibition rate, the S(180) tumour inhibition rates of 20 mg kg(-1)d(-1) two compounds were 59.5% and 48.9%, respectively.",
        "keywords": [
            "high-speed counter-current chromatography",
            "pentacyclic triterpenoids",
            "s 180",
            "sinojackia sarcocarpa l.q. luo",
            "high performance liquid chromatography",
            "infrared",
            "mass spectrometry"
        ],
        "authors": [
            {
                "name": "Sujun Liu",
                "org": "Leshan Teachers College(Leshan Teachers College,Leshan Teacher's College),Leshan,China"
            },
            {
                "name": "Mei Cao",
                "org": "Sichuan Provincial Eople's Hospital(Sichuan Provincial Eople's Hospital),Chengdu,China"
            },
            {
                "name": "Daxu Li",
                "org": "Sichuan Academy of Grassland Science(Sichuan Academy of Grassland Sciences,Sichuan Academy of Grassland Science,Academy of Sichuan Grass Science),Chengdu,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Su Feng",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Yuanyang Nie",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Liang Yan",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Dan Zhang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Yan Zhang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Zhirong Yang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Jian Zhao",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            }
        ],
        "venue": "Natural product research",
        "year": 2011
    },
    "wjeF1JKA": {
        "id": "wjeF1JKA",
        "title": "Effects of wetland degradation on bacterial community in the Zoige Wetland of Qinghai-Tibetan Plateau (China).",
        "abstract": "Wetland degradation makes significant impacts on soil, and bacterial communities in soil are likely to respond to these impacts. The purpose of this study was to investigate the impacts of soil property, soil type and soil depth on bacterial community in different stages of soil degradation in the Zoige Wetland. Microbial biomass carbon was estimated from chloroform fumigation-extraction. Bacterial communities were evaluated by cluster and principal component analysis of DGGE banding patterns and sequencing of partial 16S rDNA PCR amplicons. Experimental results showed that microbial biomass carbon decreased with the soil types (Peat soil > Swamp soil > Meadow soil > Sandy soil) and declined with soil depths (0-20 > 20-40 > 40-60 cm). Bacterial community was affected by soil type more primarily than by soil depth. In addition, the microbial biomass carbon was strongly correlated with soil water content, soil organic carbon and total nitrogen. Sequence analysis of DGGE bands indicated that bacterial phyla of α-Proteobacteria, γ-Proteobacteria, Bacteroidetes, Flavobacterium and Unidentified bacterium predominantly existed in the soil. All these results suggest that specific changes in soil property, soil type and soil depth affected soil bacterial community both quantitatively and qualitatively.",
        "keywords": [
            "bacterial communitymicrobial biomass carbonsoil propertysoil typesoil depthpcr-dgge"
        ],
        "authors": [
            {
                "name": "Jie Tang",
                "org": "Key Laboratory of Biological Resource and Ecological Environment of the Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, 610064 PR, China"
            },
            {
                "name": "Xiang Ding",
                "org": "Key Laboratory of Biological Resource and Ecological Environment of the Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, 610064 PR, China"
            },
            {
                "name": "Liming Wang",
                "org": "Key Laboratory of Biological Resource and Ecological Environment of the Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, 610064 PR, China"
            },
            {
                "name": "Qingrui Xu",
                "org": "Key Laboratory of Biological Resource and Ecological Environment of the Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, 610064 PR, China"
            },
            {
                "name": "Zhirong Yang",
                "org": "Key Laboratory of Biological Resource and Ecological Environment of the Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, 610064 PR, China"
            },
            {
                "name": "Jian Zhao",
                "org": "Key Laboratory of Biological Resource and Ecological Environment of the Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, 610064 PR, China"
            },
            {
                "name": "Qun Sun",
                "org": "Key Laboratory of Biological Resource and Ecological Environment of the Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, 610064 PR, China"
            },
            {
                "name": "Su Feng",
                "org": "Key Laboratory of Biological Resource and Ecological Environment of the Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, 610064 PR, China"
            },
            {
                "name": "Jie Zhang",
                "org": "Key Laboratory of Biological Resource and Ecological Environment of the Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, 610064 PR, China"
            }
        ],
        "venue": "World journal of microbiology & biotechnology",
        "year": 2012
    },
    "oLw64EK2": {
        "id": "oLw64EK2",
        "title": "Formation, evolution and environmental changes of the Gyirong Basin and uplift of the Himalaya",
        "abstract": "During the period from 7.0 to 1.7 Ma B. P., the Gyirong Basin formed in the Late Miocene was filled with more than 300m of fluvio-lacustrine sediments. Since 1.7Ma B.P., the Himalaya has been strongly rising and the basin dissected by the river on the southern slope of the Himalaya had finished its sedimentary history. Based on the data on sedimentology, magnetostratigraphy, paleontology and oxygen and carbon isotope, the tectonic and climatic events since the Late Miocene are reconstructed. It is pointed out that the Himalaya uplift commenced before 7.0Ma B.P., but the strong uplift took place during 2.0-1.7 and after 0.8Ma B.P., the most important climatic events took place between 5.7 and 2.5Ma B.P., the climatic cycles in the glacial and interglalcial periods began at 1.7Ma B.P. and was strengthened after 0.8Ma B.P.",
        "keywords": [
            "gyirong basin",
            "late cenozoic",
            "tectonic and climatic events",
            "the himalaya"
        ],
        "authors": [
            {
                "name": "Fubao Wang",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Shengfeng Li",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Xuhui Shen",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Ge Yan",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            }
        ],
        "venue": "Science in China, Series D: Earth Sciences",
        "year": 1996
    },
    "ycVnKmyA": {
        "id": "ycVnKmyA",
        "title": "Oasis-desert landscape heterogeneity and spatial scaling of Fukang transect in Xinjiang, China",
        "abstract": "Based on aerial images the GIS technique supported by ARC/INFO software was used to analyze the oasis-desert landscape heterogeneity and its dynamics of Fukang transect with spatial scale change, using landscape structural indices to reveal and compare the structural characteristics of oasis-desert landscape heterogeneity, which was useful to study the dynamics process of landscape heterogeneity through time from different aspect in arid area, which was useful to study the dynamics process of landscape heterogeneity. The results show that oasis-desert landscape in studied area was controlled by the combination of environment heterogeneity, human dimension and activities, and natural vegetation succession. The mutation, contrast and heterogeneity of ecological interface between oasis and desert ecosystem increased. Rare natural or non-regional mosaic of patch show obvious sensitivity to spatial scale, the change ratios of theirs area and perimeter are greater than large patch. With the disturbance of moderate scale more small patchiness combines into more large patchiness. But more patchiness of mosaic will vanish with violent disturbances or isolations of scales. At the same time it has proved that the analysis of landscape heterogeneity is quite effective research means in ecology to measure and quantify the relationship, interaction and response between the structure and function, patterns and processes of oasis-desert ecosystem.",
        "keywords": [
            "ecosystem",
            "landscape heterogeneity",
            "oasis-desert",
            "patch",
            "spatial scaling",
            "ecosystems",
            "interfaces",
            "spatial scale",
            "ecology",
            "geographic information systems"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Xinjiang University(Xinjiang University),Urumqi,China"
            },
            {
                "name": "Xiaoling Pan",
                "org": "Xinjiang University(Xinjiang University),Urumqi,China"
            },
            {
                "name": "QingDong Shi",
                "org": "Xinjiang University(Xinjiang University),Urumqi,China"
            },
            {
                "name": "Guanghui Lü",
                "org": "Xinjiang University(Xinjiang University),Urumqi,China"
            }
        ],
        "venue": "Proceedings of SPIE - The International Society for Optical Engineering",
        "year": 2003
    },
    "81xAHi20": {
        "id": "81xAHi20",
        "title": "Responses of net primary productivity (NPP) in Xinjiang to climatic changes from 1981 to 2000",
        "abstract": "In the last several decades, the responses of vegetation to global changes at regional and global scales have been studied with many mathematical models primarily driven by point meteorological observations. In this study, the net primary productivity (NPP) of Xinjiang, China is simulated using the GLObal Production Efficiency Model (GLO-PEM) which is a semi-mechanistic model of plant photosynthesis and respiration and driven entirely by satellite observations. With the available satellite observation data acquired from NOAA's Advanced Very High Resolution Radiometer (AVHRR), the seasonal and inter-annual changes of NPP in the Xinjiang area are analyzed for the time period of 20 years from 1981 to 2000. Large spatial variability of NPP is found in this area. The temporal trends of NPP in different regions of the area differed significantly. However, for the whole area the mean annual NPP decreased in the 1980s and increased in the 1990s. Seasonal variations of NPP are large and inter-annual changes are moderate. The correlations between the simulated NPP and the precipitation and temperature suggested that precipitation and temperature played major roles in the variations of NPP.",
        "keywords": [
            "CEVSA model",
            "GLO-PEM model",
            "NPP",
            "Precipitation",
            "Temperature"
        ],
        "authors": [
            {
                "name": "Wei Gao",
                "org": "Colorado State University(Colorado State University),Fort Collins,United States"
            },
            {
                "name": "Zhiqiang Gao",
                "org": "Institute of Geographical Sciences and Natural Resources Research Chinese Academy of Sciences(Chinese Academy of Sciences,CAS),Beijing,China"
            },
            {
                "name": "Xiaoling Pan",
                "org": "Xinjiang University(Xinjiang University),Urumqi,China"
            },
            {
                "name": "James R. Slusser",
                "org": "Colorado State University(Colorado State University),Fort Collins,United States"
            },
            {
                "name": "Mingkui Cao",
                "org": "University of Maryland(University of Maryland),College Park,United States"
            },
            {
                "name": "Jiaguo Qi",
                "org": "Michigan State University(Michigan State University),East Lansing,United States"
            },
            {
                "name": "Jie Zhang",
                "org": "Xinjiang University(Xinjiang University),Urumqi,China"
            },
            {
                "name": "Xiwu Zhan",
                "org": "NASA Goddard Space Flight Center(NASA Goddard Space Flight Center,NASA/Goddard Space Flight Center),Greenbelt,United States"
            },
            {
                "name": "Yingjun Ma",
                "org": "Xinjiang Ctr. of Rsrc./Environment(Xinjiang Ctr. of Rsrc./Environment,Xinjiang Ctr. of Environ. Meteorol.,Xinjiang Resource and Environment Center),Urumqi,China"
            }
        ],
        "venue": "Proceedings of SPIE - The International Society for Optical Engineering",
        "year": 2003
    },
    "hGDbVdHd": {
        "id": "hGDbVdHd",
        "title": "Landscape Heterogeneity and Net Primary Productivity (NPP) of Mountain-Oasis-Desert Ecosystems in Western China",
        "abstract": "This study was conducted to develop an appropriate assessment technique to define impact of mountain-desert-oasis ecosystem on net primary productivity (NPP) in northern foothills of Tianshan Mountains. Geographic Information System (GIS) was used to estimate land use/land cover of the mountain, desert and oasis zones. An ecological process model was used to estimate NPP by using data entirely derived from satellite. The results show that landscape heterogeneity was important factor to affect NPP values in mountain-desert-oasis ecosystem. Simulated results indicated a total annual NPP of 1.5081×10 14g C for selected transect in 2002. There was 32.67% of total NPP which came from oasis areas, 28.16% from alpine meadows areas, 9.15% from forests area. Mean NPP values over the selected transect was 150.29 g C m -2 year -1 in 2002. However, NPP values varied greatly with different geography and season.",
        "keywords": [
            "desert",
            "gis",
            "heterogeneity",
            "land use/land cover",
            "landscape structure",
            "net primary productivity",
            "oasis",
            "remote sensing",
            "seasonality",
            "geographic information system",
            "process model",
            "ecosystems",
            "geographic information systems",
            "geography",
            "satellites"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Xinjiang University(Xinjiang University),Urumqi,China"
            },
            {
                "name": "Xiaoling Pan",
                "org": "Intl. Ctr. D.A.-R.S.D.A./S.-A.L.(Intl. Ctr. D.A.-R.S.D.A./S.-A.L.),Urumqi,China"
            },
            {
                "name": "Zhiqiang Gao",
                "org": "Intl. Ctr. D.A.-R.S.D.A./S.-A.L.(Intl. Ctr. D.A.-R.S.D.A./S.-A.L.),Urumqi,China"
            },
            {
                "name": "Wei Gao",
                "org": "Intl. Ctr. D.A.-R.S.D.A./S.-A.L.(Intl. Ctr. D.A.-R.S.D.A./S.-A.L.),Urumqi,China"
            },
            {
                "name": "Suling Zhao",
                "org": "Intl. Ctr. D.A.-R.S.D.A./S.-A.L.(Intl. Ctr. D.A.-R.S.D.A./S.-A.L.),Urumqi,China"
            },
            {
                "name": "QingDong Shi",
                "org": "Intl. Ctr. D.A.-R.S.D.A./S.-A.L.(Intl. Ctr. D.A.-R.S.D.A./S.-A.L.),Urumqi,China"
            },
            {
                "name": "Guanghui Lv",
                "org": "Intl. Ctr. D.A.-R.S.D.A./S.-A.L.(Intl. Ctr. D.A.-R.S.D.A./S.-A.L.),Urumqi,China"
            }
        ],
        "venue": "Proceedings of SPIE - The International Society for Optical Engineering",
        "year": 2003
    },
    "bXQJEO0d": {
        "id": "bXQJEO0d",
        "title": "Progress report of research on eco-environmental evolution, control and adjustment for arid land in Western China",
        "abstract": "Since we started the National Key Project of Fundamental Research (China), \"The research on eco-environmental evolution, control and adjustment for arid land in Western China\", four years ago we have made a number of important progresses. These progresses include many research fields: the palaeoclimate rebuilding and environmental change; the development process and driving forces of oases; the water-salt balance and main hydrology processes of oases; the oasis ecosystem's structure, ecological process and stability; the coupling mechanism of three major ecosystems of mountain, oasis, and desert; the ecological landscape patterns' evolution and its responses climate change; the ecological environmental effects of large industrial (construction) projects; the cause and spatial-temporal distribution of desertification; the establishment of experimental demonstration bases of ecological recovery and rebuilding; and adjustment and control of ecosystem and management models.",
        "keywords": [
            "arid land",
            "ecosystem",
            "environment",
            "evolution and control",
            "climate change",
            "desertification",
            "water",
            "ecosystems",
            "development process",
            "hydrology",
            "environmental change"
        ],
        "authors": [
            {
                "name": "Xiaoling Pan",
                "org": "Xinjiang University(Xinjiang University),Urumqi,China"
            },
            {
                "name": "Wei Gao",
                "org": "Colorado State University(Colorado State University),Fort Collins,United States"
            },
            {
                "name": "Yingjun Ma",
                "org": "Xinjiang Rsrc./Environment Center(Xinjiang Rsrc./Environment Center),Urumqi,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Xinjiang University(Xinjiang University),Urumqi,China"
            },
            {
                "name": "Qifeng Lu",
                "org": "Nanjing University of Information Science and Technology(Nanjing University of Information Science and Technology ^),Nanjing,China"
            },
            {
                "name": "Guanghui Lv",
                "org": "Xinjiang University(Xinjiang University),Urumqi,China"
            },
            {
                "name": "Weiqing Li",
                "org": "Intl. Ctr. D.A.-R.S.D.A./S.-A.L.(Intl. Ctr. D.A.-R.S.D.A./S.-A.L.),Urumqi,China"
            },
            {
                "name": "QingDong Shi",
                "org": "Xinjiang University(Xinjiang University),Urumqi,China"
            }
        ],
        "venue": "Proceedings of SPIE - The International Society for Optical Engineering",
        "year": 2003
    },
    "C68vDmkG": {
        "id": "C68vDmkG",
        "title": "Preliminary study on the relationship between temporal and spatial evolution of ecological landscape pattern and climate change in Xinjiang, China",
        "abstract": "Fractional vegetation cover data (FVC) based on the annual maximum NOAA/AVHRR NDVI (Advanced Very High Resolution Radiometer normalized difference vegetation index) data and the ground meteorological data have been used to analyze the relationship between the temporal and spatial evolution of ecological landscape pattern and climate change in Xinjiang autonomous region, China from 1982 to 1993. It is found that during this period, the averaged oasis cropland or low-damp forest-shrub meadow area occupies 7.50% of the whole region, desert dune/barren desert 25.70%; temperate semi-arbor desert 21.70%; temperate shrub and semi-shrub desert 8.36%; alpine subalpine desert steppe 7.71%; temperate gramineous and ruderal steppe 7.63%; mountain forest steppe 2.13%; high-cold barren 8.93%; high-cold low semi-shrub desert 9.08%; water/ice 1.26%. Compared with the 30-year (1961-1990) climatology, the 12-year averaged annual surface air temperature and precipitation over the whole region increase by 0.28 °C and 23.6 mm respectively. The maximum increase of precipitation does not occur over the mountain region; instead it occurs over the region with a concentrated distribution of oases, suggesting the positive role of oases in adjusting regional climate. The area of temporal steppe also increases with the increase of precipitation and temperature. Together, these results demonstrate that, during the 12-year period, the condition of vegetation cover has been improved and large-scale desertification does not occur in Xinjiang.",
        "keywords": [
            "climate change",
            "desert",
            "ecological landscape",
            "fvc",
            "oasis",
            "response",
            "xinjiang",
            "water",
            "normalized difference vegetation index",
            "desertification",
            "climatology"
        ],
        "authors": [
            {
                "name": "Xiaoling Pan",
                "org": "Xinjiang University(Xinjiang University),Urumqi,China"
            },
            {
                "name": "Xubin Zeng",
                "org": "University of Arizona(University of Arizona),Tucson,United States"
            },
            {
                "name": "Jie Zhang",
                "org": "Xinjiang University(Xinjiang University),Urumqi,China"
            },
            {
                "name": "QingDong Shi",
                "org": "Xinjiang University(Xinjiang University),Urumqi,China"
            },
            {
                "name": "Qing He",
                "org": "Xinjiang Meteorological Bureau(Xinjiang Institute of Meteorology,Environmental Meteorological Center of Xinjiang,Xinjiang Meteorological Bureau),Urumqi,China"
            },
            {
                "name": "Qincheng Chao",
                "org": "National Climate Center Beijing(National Climate Center),Beijing,China"
            },
            {
                "name": "Jiping Chao",
                "org": "National Climate Center Beijing(National Climate Center),Beijing,China"
            }
        ],
        "venue": "Proceedings of SPIE - The International Society for Optical Engineering",
        "year": 2003
    },
    "ObOKWZlO": {
        "id": "ObOKWZlO",
        "title": "Rates and patterns of change in two contrasting oasis agricultural landscapes in Xinjiang, China",
        "abstract": "We used Landsat TM imagery and GIS to quantify the rates and patterns of landscape change of two different oasis ecosystems transects - Fukang oasis and Yutian oasis in Xinjiang Uygur autonomous region, P. R. China. Human dimension is a major disturbance agent throughout the area and desert-oasis ecotone is also important. Maximum likelihood classification of satellite imagery identified landscape class types and changes among the landscape mosaics in two transects. Rate and pattern of the spatial and temporal of landscape change in two oases agricultural landscapes were detected at class and landscape level. The resulting landscape changes have a multitude of consequences; for agricultural production, landscape aesthetics, recreational and amenity values of the landscape, and for biodiversity.Results show that further intensification of the intensively managed landscape has led to an increasingly homogeneous, large-scale landscape featuring fewer boundaries. In contrast, reduced management in the oasis-farm system has resulted in an increasingly heterogeneous, small-scale landscape. The main pattern and key factors of dynamic changes of oasis-desert heterogeneity with frequent human's activities especially land use were discussed. Because land use changes are triggered by socioeconomic forces in two oases, a through comprehension of historical change will enhance our capability to predict future landscape dynamics and devise effective landscape management strategies.",
        "keywords": [
            "landscape",
            "oasis agriculture",
            "pattern and process",
            "agriculture",
            "land use",
            "ecosystems",
            "agricultural production",
            "land use change",
            "geographic information systems"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Xinjiang University(Xinjiang University),Urumqi,China"
            },
            {
                "name": "Xiaoling Pan",
                "org": "Xinjiang University(Xinjiang University),Urumqi,China"
            },
            {
                "name": "QingDong Shi",
                "org": "Xinjiang University(Xinjiang University),Urumqi,China"
            },
            {
                "name": "Guanghui Lv",
                "org": "Xinjiang University(Xinjiang University),Urumqi,China"
            }
        ],
        "venue": "Proceedings of SPIE - The International Society for Optical Engineering",
        "year": 2003
    },
    "GgRFwWAb": {
        "id": "GgRFwWAb",
        "title": "Vegetation evolution in arid land of western China",
        "abstract": "NDVI (Normalized Difference Vegetation Index) values range from -1.0 to +1.0, -areas with NDVI < 0 rarely contain any vegetation, while NDVI >0.6, vegetation cover reaches 100%. The FVC (Fractional Vegetation Cover) values range from 0 to +1.0. Above this threshold the fractional vegetation cover increases approximately as the square of the NDVI, and reaches 100% at an upper NDVI threshold, which is considerably less than 1.0. In arid and semi-arid regions, FVC is superior to NDVI. In this article we got the classification rules by using the resolution 1km FVC combining with DEM (Digital Elevation Model) to classify the vegetation types in arid parts of western China. This classification system was used to classify all FVC images of the resolution 8km*8km from 1982a to 2000a, in this way, we got the classification maps of vegetation for every year. From these classification maps we calculated three majority maps from 1982-1989a, 1990-1995a and 1996-2000a. Supported by software ARC/INFO allowed us to identify whether cells were degraded or improved after comparing-every cell value at same location in three serial maps and then getting the evolution map of vegetation. The main results are as follows: 1) the vegetation in all of arid west China has increased; 2) the vegetation was increased and the rate is higher than in all study area; cells showing improvement in mountainous areas are almost equal to cells showing degradations) there were two types of improvement patches; the oasis patch increases around old oases and the plain sparse desert patch has also increased; 4) degradation patches appear more frequently in the lower reaches of the Tarim River, in all reaches of Cherchen River, the Jungger basin and to the south of Alxa Right County of Inner Mongolia; 5) in mountainous areas, most of the improvement cells took place in the south of the Tianshan mountains and Pamir high plain, degradation cells are located on the slope of the north Kunlun mountains as a long narrow region and big patch assembled in the Aljin Mountains and the north slope of the Qilian Mountains.",
        "keywords": [
            "arid land in western china",
            "evolution of vegetation",
            "fractional vegetation cover",
            "remote sensing",
            "vegetation evolvement vegetation classification",
            "classification system",
            "normalized difference vegetation index",
            "digital elevation model"
        ],
        "authors": [
            {
                "name": "QingDong Shi",
                "org": "Nanjing University of Information Science and Technology(Nanjing University of Information Science and Technology ^),Nanjing,China"
            },
            {
                "name": "Guanhui Lu",
                "org": "Xinjiang University(Xinjiang University),Urumqi,China"
            },
            {
                "name": "Jidong Xiao",
                "org": "Xinjiang Meteorological Bureau(Xinjiang Institute of Meteorology,Environmental Meteorological Center of Xinjiang,Xinjiang Meteorological Bureau),Urumqi,China"
            },
            {
                "name": "Xiaoling Pan",
                "org": "Xinjiang University(Xinjiang University),Urumqi,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Xinjiang University(Xinjiang University),Urumqi,China"
            },
            {
                "name": "Liangnian Ji",
                "org": "Xinjiang Meteorological Bureau(Xinjiang Institute of Meteorology,Environmental Meteorological Center of Xinjiang,Xinjiang Meteorological Bureau),Urumqi,China"
            },
            {
                "name": "Shunli Chang",
                "org": "Xinjiang University(Xinjiang University),Urumqi,China"
            }
        ],
        "venue": "Proceedings of SPIE - The International Society for Optical Engineering",
        "year": 2003
    },
    "wSw1ff9H": {
        "id": "wSw1ff9H",
        "title": "Carbon uptake and change in net primary productivity of oasis-desert ecosystem in arid western China with remote sensing technique",
        "abstract": "Arid and semi-arid ecosystems exhibit a spatially complex biogeophysical structure. According to arid western special climate-vegetation\n characters, the fractional cover of photosynthetic vegetation (PV), non-photosynthetic vegetation (NPV), bare soil and water\n are unmixed, using the remote sensing spectral mixture analysis. We try the method to unmix the canopy funation structure\n of arid land cover in order to avoid the differentiation of regional vegetation system and the disturbance of environmental\n background. We developed a modified production efficiency model NPP-PEM appropriate for the arid area at regional scale based\n on the concept of radiation use efficiency. This model refer to the GLO-PEM and CASA model was driven with remotely sensed\n observations, and calculates not just the conversion efficiency of absorbed photosynthetically active radiation but also the\n carbon fluxes that determine net primary productivity (NPP). We apply and validate the model in the Kaxger and Yarkant river\n basins in arid western China. The NPP of the study area in 1992 and 1998 was estimated based on the NPP-PEM model. The results\n show that the improved PEM model, considering the photosynthetical activation of heterogeneous functional vegetation, is in\n good agreement with field measurements and the existing literature. An accurate agreement (R\n 2 = 0.85, P<0.001) between the estimates and the ground-based measurement was obtained. The spatial distribution of mountain-oasis-desert\n ecosystem shows an obvious heterogeneous carbon uptake. The results are applicable to arid ecosystem studies ranging from\n characterizing carbon cycle, carbon flux over arid areas to monitoring change in mountain-oasis-desert productivity, stress\n and management.",
        "keywords": [
            "net primary productivity",
            "kaxger",
            "desert",
            "spectral mixture analysis",
            "arid western area",
            "oasis",
            "npp-pem",
            "carbon cycle",
            "remote sensing",
            "conversion efficiency",
            "net primary production",
            "river basin",
            "production efficiency"
        ],
        "authors": [
            {
                "name": "zhang",
                "org": "nanjing university"
            },
            {
                "name": "jie",
                "org": "xinjiang university"
            },
            {
                "name": "pan",
                "org": ""
            },
            {
                "name": "xiaoling",
                "org": "xinjiang university"
            },
            {
                "name": "gao",
                "org": "xinjiang university"
            },
            {
                "name": "zhiqiang",
                "org": "nanjing university"
            },
            {
                "name": "shi",
                "org": "nanjing university"
            },
            {
                "name": "qingdong",
                "org": "nanjing university"
            },
            {
                "name": "lv",
                "org": "nanjing university"
            },
            {
                "name": "guanghui",
                "org": "nanjing university"
            }
        ],
        "venue": "Journal of Geographical Sciences",
        "year": 2006
    },
    "HGGUf2Z0": {
        "id": "HGGUf2Z0",
        "title": "Study on the combined application of laparoscopic cholecystectomy and endoscopic sphincterotomy in treatment of cholecystolithiasis and secondary choledocholithiasis",
        "abstract": "Objective To study the therapeutic effects of combined use of laparoscopic cholecystetomy and endoscopic sphincterotomy for cholecystolithiasis with secondary choledocholithiasis.Methods Thirty-five patients were diagnosed as cholecystolithiasis with secondary choledocholithiasis by B-ultrasonography and magnetic resonance cholangiopancreatography.Of them,in 28 cases,laparoscopic cholecystetomy was performed first,and ERCP and endoscopic sphincterotomy were done one week later;in 7 cases,endoscopic sphincterotomy were performed before laparoscopic cholecystectomy.Results The outcome of all the thirty-five cases was satisfactory without severe complications or conversion into open procedure.Conclusions The method of combined laparoscopic cholecystomy and endoscopic sphincterotomy,for cholecystolithiasis with secondy choledocholithiasis,especially for cases in whom the diameter of the common bile duct stone is ≤1cm,can give good therapeutic results and has advantages of minimal invasiveness,few complications and quick recovery.",
        "keywords": [
            "Choledocholithiasis/surg",
            "Cholelithiasis/surg",
            "Endoscpic Sphincterotomy",
            "Laparoscopy",
            "Cholecystomy"
        ],
        "authors": [
            {
                "name": "TIAN Da-guang",
                "org": "Department of Hepatobiliopancreas Surgery,the Second Affiliated Hospital,Kunming Medical College,Kunming ,China"
            },
            {
                "name": "HUANG Jie",
                "org": "Department of Hepatobiliopancreas Surgery,the Second Affiliated Hospital,Kunming Medical College,Kunming ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Hepatobiliopancreas Surgery,the Second Affiliated Hospital,Kunming Medical College,Kunming ,China"
            },
            {
                "name": "RAN Jiang-hua",
                "org": "Department of Hepatobiliopancreas Surgery,the Second Affiliated Hospital,Kunming Medical College,Kunming ,China"
            },
            {
                "name": "WEI Xiao-ping",
                "org": "Department of Hepatobiliopancreas Surgery,the Second Affiliated Hospital,Kunming Medical College,Kunming ,China"
            },
            {
                "name": "DONG Guo-hai",
                "org": "the Second Department of Surgery,Yun Nan Provincial Police General Hospital,Kunming ,China"
            }
        ],
        "venue": "Chinese Journal of General Surgery",
        "year": 2006
    },
    "HSF18fl6": {
        "id": "HSF18fl6",
        "title": "Experimental Study of pcDNA3/AFP/TK/Angio Fusion Gene Targeting Therapy for Human Primary Liver Cancer",
        "abstract": "Objective To study the effects of pcDNA3/AFP/TK/Angio fusion gene targeting therapy for human primary liver cancer in nude mice implanted with SMMC-7721. Methods Human liver cancer cell line SMMC-7721 was implanted subcutaneously in nude mice to establish experiment model. Animals bearing liver cancer were randomly divided into five groups: control group, vector group, GCV (ganciclovir) group, pcDNA3/TK/Angio group; pcDNA3/AFP/TK/Angio group. Different plasmids were directly injected into tumors and GCV was intraperitoneally administrated simultaneously according to different groups. The growth of tumors was observed and the pathology was examined as well. Serum AFP level was measured by radioimmunology, the ultrastructural change of tumor cells was studied by using electron microscopy, the expressions of MVD and VEGF were respectively detected with immunohistochemistry and the cell apoptosis in situ was detected by TUNEL. Results The success rate to establish subcutaneous implanted liver cancer model in nude mice was 100%. The tumor volume, serum AFP level, VEGF and MVD expressions of pcDNA3/TK/Angio group and pcDNA3/AFP/TK/Angio group were lower than those in control group, vector group and GCV group (P<0.05) and more apoptosis cells could be observed. While the tumor volume, serum AFP level, VEGF and MVD expressions of pcDNA3/AFP/TK/Angio group was lower than those in pcDNA3/TK/Angio group (P<0.05); and apoptosis index was higher than that of the latter (P<0.05). Conclusion pcDNA3/AFP/TK/Angio fusion gene inhibits the growth of tumor remarkably and becomes a promising new biological agent to treat human primary liver cancer.",
        "keywords": [
            "Primary liver cancer Gene therapy Target Fusion gene Angiostatin gene Suicide gene"
        ],
        "authors": [
            {
                "name": "SHENG Qin-song",
                "org": ". Department of Hepatobiliary Surgery, The Second Affiliated Hospital of Kunming Medical College, Kunming , China"
            },
            {
                "name": "WANG Lin",
                "org": ". Department of Hepatobiliary Surgery, The Second Affiliated Hospital of Kunming Medical College, Kunming , China"
            },
            {
                "name": "REN Feng",
                "org": ". Department of Hepatobiliary Surgery, The Second Affiliated Hospital of Kunming Medical College, Kunming , China"
            },
            {
                "name": "LU Yong-gang",
                "org": ". Department of Hepatobiliary Surgery, The Second Affiliated Hospital of Kunming Medical College, Kunming , China"
            },
            {
                "name": "ZOU Hao",
                "org": ". Department of Hepatobiliary Surgery, The Second Affiliated Hospital of Kunming Medical College, Kunming , China"
            },
            {
                "name": "XIAO Shu-feng",
                "org": ". Department of Hepatobiliary Surgery, The Second Affiliated Hospital of Kunming Medical College, Kunming , China"
            },
            {
                "name": "TANG Bo",
                "org": ". Department of Hepatobiliary Surgery, The Second Affiliated Hospital of Kunming Medical College, Kunming , China"
            },
            {
                "name": "HUANG Jie",
                "org": ". Department of Hepatobiliary Surgery, The Second Affiliated Hospital of Kunming Medical College, Kunming , China"
            },
            {
                "name": "ZHANG Jie",
                "org": ". Department of Hepatobiliary Surgery, The Second Affiliated Hospital of Kunming Medical College, Kunming , China"
            }
        ],
        "venue": "Chinese Journal of Bases and Clinics in General Surgery",
        "year": 2007
    },
    "NL3XBUVq": {
        "id": "NL3XBUVq",
        "title": "The Application Value of Choledochfiberscope in Treatment of the Residual Bile Duct Stones after Operation",
        "abstract": "Objective To summarize the experiences of the application of choledochfiberscope in the treatment of residual bile duct stones after operation.Methods Retrospective analyses of the effects of choledochfiberscope on 60 patients with residual bile duct stones after operation were carried out in our hospitals from Jan.2005 to Jan.2006.Results Stones were removed completely in the 60 cases,including successful 51 cases in the first attempt(85.0%)and 9 cases in the second attempt(15.0%).The biggest stone was 3.5cm×2.5cm×2.0cm.NO serious complications occurred.Conclusion The method of choledochfiberscope can be efficient in removing the residual bile duct stones after operation.The procedure is a safe way to treat residual stones and deserves clinical application.",
        "keywords": [
            "Residual bile duct stones",
            "Treatment",
            "Choledochfiberscope"
        ],
        "authors": [
            {
                "name": "HUANG Jie",
                "org": ")%%#1%%#Dept.of Hepatobilairy Surgery,The 2nd Affiliated Hospital of Kunming Medical College,Kunming "
            },
            {
                "name": "TIAN Da-guang",
                "org": ")%%#1%%#Dept.of Hepatobilairy Surgery,The 2nd Affiliated Hospital of Kunming Medical College,Kunming "
            },
            {
                "name": "ZHANG Jie",
                "org": ")%%#1%%#Dept.of Hepatobilairy Surgery,The 2nd Affiliated Hospital of Kunming Medical College,Kunming "
            },
            {
                "name": "WEI Xiao-ping",
                "org": ")%%#1%%#Dept.of Hepatobilairy Surgery,The 2nd Affiliated Hospital of Kunming Medical College,Kunming "
            },
            {
                "name": "DONG Guo-hai",
                "org": "Dept.of Surgery,Police Armed Hospital of Yunnan,Kunming ,China)"
            }
        ],
        "venue": "Journal of Kunming Medical College",
        "year": 2007
    },
    "sipeWKMK": {
        "id": "sipeWKMK",
        "title": "Therapeutic effects of gemcitabine regional artery perfusion combined with systemic chemotherapy for late-stage cancer of pancreas",
        "abstract": "Objective To evaluate the therapeutic effects of gemcitabine regional artery perfusion combined with systemic chemotherapy for late-stage cancer of pancreas.Methods Thirteen cases of late-stage cancer of pancreas proven by operation and pathology were treated with 5-FU+MMC as a combined system chemotherapy, and use of gemcitabine for regional artery perfusion chemotherapy.Results Among the 13 patients who could be evaluated for therapeutic effect, four cases had partial response (PR), six cases had (SD), three cases were PD, and the effective rate of the clinical benifical-reflected evaluation was 76.9%, pain releive rate 75.0% the median survival time was 6.3 months. None of the patients have had serious toxious side-effects.Conclusions The gemcitabine regional artery perfusion combined with systemic chemotherapy can relieve the cancer pain of patients with late-stage cancer of pancreas, improve their general condition, increase the survival quality of life, prolong the survival time. The drug tolerance of the patients is good.",
        "keywords": [
            "Regonal",
            "Perfusion",
            "Pancreatic Neoplasms/drug ther",
            "Chemotherapy",
            "Gemcitabine/ther uses"
        ],
        "authors": [
            {
                "name": "HUANG Jie",
                "org": "Department of Hepatobilairy Surgery,the Second Affiliated Hospital,Kunming Medical College,Kunming ,China"
            },
            {
                "name": "TIAN Da-guang",
                "org": "Department of Hepatobilairy Surgery,the Second Affiliated Hospital,Kunming Medical College,Kunming ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Hepatobilairy Surgery,the Second Affiliated Hospital,Kunming Medical College,Kunming ,China"
            },
            {
                "name": "LI Tie-han",
                "org": "Department of Hepatobilairy Surgery,the Second Affiliated Hospital,Kunming Medical College,Kunming ,China"
            },
            {
                "name": "WEI Xiao-ping",
                "org": "Department of Hepatobilairy Surgery,the Second Affiliated Hospital,Kunming Medical College,Kunming ,China"
            },
            {
                "name": "LI Chun-man",
                "org": "Department of Hepatobilairy Surgery,the Second Affiliated Hospital,Kunming Medical College,Kunming ,China"
            },
            {
                "name": "HU Ming-dao",
                "org": "Department of Hepatobilairy Surgery,the Second Affiliated Hospital,Kunming Medical College,Kunming ,China"
            }
        ],
        "venue": "Chinese Journal of General Surgery",
        "year": 2007
    },
    "MHGA7FqT": {
        "id": "MHGA7FqT",
        "title": "The combination of direct digital radiography and electrohydraulic shockwave lithotripsy in treatment of residual bile duct stones",
        "abstract": "Objective To summaize the experience of application of direct digital radiography and electrohydraulic shockwave lithotripsy in treatment of residual bile duct stones.Methods A retrospective analysis of clinical records of 60 patients with residual bile duct stones treated in our hospital from 2003 to 2006 was made.Results In 59(95.9%) of 60 cases the stones were removed completely,including successful removal in one time of application of this method in 57 Patients(95.0 %),and 2 applications in 2 Patients ﹙3.3 %).One case with bile duct stone complicated with dile duct cancer was unsuccessful.The biggest stone was 3.5 cm×2.5 cm×2.0 cm.No serious complications occurred and changed to operation.The 59 cases were followed up for 6 mo to l yr,and all had a successful outcome.Conclusions The method of combination of direct digital radiography and electrohydraulic shockwave lithotripsy in treatment of postoperative residual bile duct stones after operation can facilitate removal of residual bile duct stones.The procedure is a safe way of treating residual stones.",
        "keywords": [
            "Electrohydraulic Shockwave Lithotripsy",
            "Direct Digital Radiography",
            "Residual Bile Duct Stones",
            "Cholelithiasis/ther"
        ],
        "authors": [
            {
                "name": "TIAN Da-guang",
                "org": "(Department of Hepatobiliopancreatic Surgery,the Second Affiliated Hospital,Kunming Medical College,Kunming ,China)"
            },
            {
                "name": "ZHU Quan-sheng",
                "org": "(Department of Hepatobiliopancreatic Surgery,the Second Affiliated Hospital,Kunming Medical College,Kunming ,China)"
            },
            {
                "name": "HUANG Jie",
                "org": "(Department of Hepatobiliopancreatic Surgery,the Second Affiliated Hospital,Kunming Medical College,Kunming ,China)"
            },
            {
                "name": "ZHANG Jie",
                "org": "(Department of Hepatobiliopancreatic Surgery,the Second Affiliated Hospital,Kunming Medical College,Kunming ,China)"
            },
            {
                "name": "LI Tie-han",
                "org": "(Department of Hepatobiliopancreatic Surgery,the Second Affiliated Hospital,Kunming Medical College,Kunming ,China)"
            },
            {
                "name": "WEI Xiao-ping",
                "org": "(Department of Hepatobiliopancreatic Surgery,the Second Affiliated Hospital,Kunming Medical College,Kunming ,China)"
            },
            {
                "name": "HU Ming-dao",
                "org": "(Department of Hepatobiliopancreatic Surgery,the Second Affiliated Hospital,Kunming Medical College,Kunming ,China)"
            },
            {
                "name": "LI Wen",
                "org": "(Department of Hepatobiliopancreatic Surgery,the Second Affiliated Hospital,Kunming Medical College,Kunming ,China)"
            }
        ],
        "venue": "Chinese Journal of General Surgery",
        "year": 2007
    },
    "BpLJraok": {
        "id": "BpLJraok",
        "title": "Analysis of the Death Factors in 87 Cases of Abdominal Operations",
        "abstract": "Objective To explore the Death Factors of Abdominal Operations so as to summarize the clinical prevention and cure experience. Methods Retrospective analyses of 87 death Cases of Abdominal Operations from 2000 to 2008.Results Pulmonary infection is in 18(20.7%) after 87 Cases of Abdominal Operations,while the Respiration and circulation failure was 23(26.4%),liver and renal failure was 11(12.6%),MOF was 38(48.7%)and others were 15 cases.The complications of respiration and circulation system were happened commonly and the postoperative mortality was highly in elderly patients and emergency operation.Conclusion To enhance the pulmonary function evaluation and monitor, ameliorate patient conditions and strengthen integrate control in Perioperative management were very important in clinical practice.",
        "keywords": [
            "Abdominal surgery",
            "Mortality",
            "Respiration and circulation failure"
        ],
        "authors": [
            {
                "name": "MA Jun-feng",
                "org": "Second Affiliated Hospital of Kunming Medical College,Yunnan Kunming ,China"
            },
            {
                "name": "TANG Bo",
                "org": "Second Affiliated Hospital of Kunming Medical College,Yunnan Kunming ,China"
            },
            {
                "name": "Li Tie-han",
                "org": "Second Affiliated Hospital of Kunming Medical College,Yunnan Kunming ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Second Affiliated Hospital of Kunming Medical College,Yunnan Kunming ,China"
            }
        ],
        "venue": "China Healthcare Frontiers",
        "year": 2008
    },
    "2zfMUZWC": {
        "id": "2zfMUZWC",
        "title": "Several Factors of Influencing Eat Orthotopic Liver Transplantation Model",
        "abstract": "Objective To improve the surgical technique of establishing a reliable rat model of orthotopic liver transplantation through analyzing and summarizing the cause of the rates of success and long term survival of the model.Methods 60 cases of orthotopic liver transplantations in rats were performed using modified Kamada’s two-cuff technique.Results The general successful rate was 90.0%(54/60).one-week survival rates was 81.7% (49/60).Conclusions The key for improving success and long term survival rate in rat liver transplantation is to master the meticulous surgical performance and can adopt to some effective steps to remedy.",
        "keywords": [
            "Rat",
            "Model",
            "Liver transplantation"
        ],
        "authors": [
            {
                "name": "TANG Bo",
                "org": "Dept. of Hepatobiliary Surgery,The 2nd Affiliated Hospital of Kunming Medical University,Kunmig Yunnan ,China "
            },
            {
                "name": "XIAO Shu-feng",
                "org": "Dept. of Hepatobiliary Surgery,The 2nd Affiliated Hospital of Kunming Medical University,Kunmig Yunnan ,China "
            },
            {
                "name": "TIAN Da-guang",
                "org": "Dept. of Hepatobiliary Surgery,The 2nd Affiliated Hospital of Kunming Medical University,Kunmig Yunnan ,China "
            },
            {
                "name": "LI Yong-zhi",
                "org": "Dept. of Hepatobiliary Surgery,The 2nd Affiliated Hospital of Kunming Medical University,Kunmig Yunnan ,China "
            },
            {
                "name": "LI Han-yu",
                "org": "Dept. of Hepatobiliary Surgery,The 2nd Affiliated Hospital of Kunming Medical University,Kunmig Yunnan ,China "
            },
            {
                "name": "ZHANG Jie",
                "org": "Dept. of Hepatobiliary Surgery,The 2nd Affiliated Hospital of Kunming Medical University,Kunmig Yunnan ,China "
            }
        ],
        "venue": "Journal of Kunming Medical University",
        "year": 2008
    },
    "eNNJpEcl": {
        "id": "eNNJpEcl",
        "title": "Relationship Between Acute Rejection and Expression of Perforin mRNA after Rat Liver Grafts",
        "abstract": "Objective To explore the relationship between acute rejection and expression levels of perforin mRNA in peripheral blood and bile after rat liver transplantation so as to look for a kind of noninvasive method to diagnose acute rejection.Methods Rat orthotopic liver transplantation model with biliary extra-drainage was established.They were divided into 4 groups: blank control group(n=20),isograft group(n=30),allograft plus cyclosporine A(CsA) group(n=30) and allograft group(n=30).Semi-quantatative RT-PCR was used to measure the expressions of perforin mRNA in bile and peripheral blood and the pathological changes of the graft were observed on postoperative days of 1,3,5,7 and 10.Results Blank control group and isograft group showed no expression of perforin mRNA in peripheral blood.The expression of perforin mRNA of peripheral blood in allograft group could be detected on day 3 after transplantation and it gradually elevated on day 5 and remained in high level during 7-11 days.In allograft plus CsA group perforin mRNA of peripheral blood continuously expressed in a low level,and the level at the same time points was significantly different compared with allograft group(P<0.05).The expression of perforin mRNA in peripheral blood was analogous with the severity degree of histologic damage.The expression of perforin mRNA can not be found in bile.Conclusion The expression of perforin mRNA in the peripheral blood offers a sensitive and noninvasive means of monitoring acute rejection.",
        "keywords": [
            "Rat",
            "Perforin",
            "Acut rejection",
            "Liver transplantation"
        ],
        "authors": [
            {
                "name": "TANG Bo",
                "org": ".1.Department of Hepatobiliopancreatology Surgery,The Second Affiliated Hospital of Kunming Medical College,Kunming ,China"
            },
            {
                "name": "XIAO Shu-feng",
                "org": "The Organ Transplantation Center of 303 Hospital of Chinese People's Liberation Army,Nanning ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": ".1.Department of Hepatobiliopancreatology Surgery,The Second Affiliated Hospital of Kunming Medical College,Kunming ,China"
            },
            {
                "name": "TIAN Da-guang",
                "org": ".1.Department of Hepatobiliopancreatology Surgery,The Second Affiliated Hospital of Kunming Medical College,Kunming ,China"
            },
            {
                "name": "TANG Ji-hong",
                "org": ".1.Department of Hepatobiliopancreatology Surgery,The Second Affiliated Hospital of Kunming Medical College,Kunming ,China"
            },
            {
                "name": "ZHU Hong",
                "org": ".1.Department of Hepatobiliopancreatology Surgery,The Second Affiliated Hospital of Kunming Medical College,Kunming ,China"
            },
            {
                "name": "LI Tie-han",
                "org": ".1.Department of Hepatobiliopancreatology Surgery,The Second Affiliated Hospital of Kunming Medical College,Kunming ,China"
            },
            {
                "name": "MA Jun-feng",
                "org": ".1.Department of Hepatobiliopancreatology Surgery,The Second Affiliated Hospital of Kunming Medical College,Kunming ,China"
            }
        ],
        "venue": "Chinese Journal of Bases and Clinics in General Surgery",
        "year": 2009
    },
    "HJOMR1o0": {
        "id": "HJOMR1o0",
        "title": "Comparison of surgical outcomes of laparoscopic exploration of common duct and traditional choledochotomy in treatment of cholelithiasis and cholithiasis",
        "abstract": "【Objective】To compare the surgical outcomes of laparoscopic exploration of common bile duct and traditional choledochotomy in treatment of cholelithiasis and cholithiasis.【Methods】 50 patients with cholecystolithiasis and secondary common bile duct stones from February 2005 to October 2006 were treated with surgical operation.Divided into two group:laparoscopic exploration of common bile duct group and traditional choledochotomy group.The surgical time,recovery,complication were observed after operation.【Results】30 patients in LCBDE' group,20 patients in traditional choledochotomic group.The operation time between the two groups had no significant difference.Compared with traditional choledochotomy group,LCBDE' group had lesser Pethidine' dosis,shorter recovery time of instestinal tract function,lower hospital cost and few complication(P <0.05).【Conclusion】Laparoscopic exploration of common bile duct in treating cholelithiasis and cholithiasis is safe and feasible with availed effect of minimal invasivenss.",
        "keywords": [
            "common bile duct exploration",
            "common bile duct calculi",
            "laparoscopy",
            "cholelithiasis"
        ],
        "authors": [
            {
                "name": "TIAN Daguang",
                "org": "1.Department of Hepatobiliary Surgery,2.Department of Minimally Invasive Abdominal Surgery,The Second Affiliated Hospital of Kunming Medicine College,Kuming,Yunnan ,P.R.China"
            },
            {
                "name": "HUANG Jie",
                "org": "1.Department of Hepatobiliary Surgery,2.Department of Minimally Invasive Abdominal Surgery,The Second Affiliated Hospital of Kunming Medicine College,Kuming,Yunnan ,P.R.China"
            },
            {
                "name": "ZHANG Jie",
                "org": "1.Department of Hepatobiliary Surgery,2.Department of Minimally Invasive Abdominal Surgery,The Second Affiliated Hospital of Kunming Medicine College,Kuming,Yunnan ,P.R.China"
            },
            {
                "name": "WEI Xiaoping",
                "org": "1.Department of Hepatobiliary Surgery,2.Department of Minimally Invasive Abdominal Surgery,The Second Affiliated Hospital of Kunming Medicine College,Kuming,Yunnan ,P.R.China"
            },
            {
                "name": "ZHU Hong",
                "org": "1.Department of Hepatobiliary Surgery,2.Department of Minimally Invasive Abdominal Surgery,The Second Affiliated Hospital of Kunming Medicine College,Kuming,Yunnan ,P.R.China"
            },
            {
                "name": "HU Mingdao",
                "org": "1.Department of Hepatobiliary Surgery,2.Department of Minimally Invasive Abdominal Surgery,The Second Affiliated Hospital of Kunming Medicine College,Kuming,Yunnan ,P.R.China"
            }
        ],
        "venue": "China Journal of Endoscopy",
        "year": 2009
    },
    "WPmWkAqw": {
        "id": "WPmWkAqw",
        "title": "Surgical Technique of Rapid Procurement and Back-table Procedures of Liver Graft of Pig",
        "abstract": "Objective To explore the method of rapid harvesting and back-table procedure of liver graft.Methods Twenty-six cases of liver grafts' harvesting and back-table procedure from January to June 2008 were analyzed retrospectively.Orthotopic abdominal aorta and superior mesentery vein perfusion with inferior vena cava drainage were applied in the method.Liver grafts were preserved and trimmed in 4 ℃ UW fluid.Results The time of procurement of liver graft was 10 min in average,no warm ischemia time of liver graft.The cold ischemia time was(2.11±0.26)hours.The time of back-table procedures were from 26 to 90 minutes and 46 minutes in average.Conclusions Harvesting and trimming of liver graft is the first and chief step of liver transplantation.The method of rapid procurement of liver graft can insure the quality of liver graft and the perfect donor operation.",
        "keywords": [
            "Pig",
            "Harvesting of liver graft",
            "Procurement of liver graft",
            "Liver transplantation"
        ],
        "authors": [
            {
                "name": "HUANG Jie",
                "org": "Dept.of Surgery,The 2nd Affiliated Hospital of Kunming Medical University,Kunming Yunnan ,China"
            },
            {
                "name": "YANG Da-kuan",
                "org": "Dept.of Surgery,The 2nd Affiliated Hospital of Kunming Medical University,Kunming Yunnan ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Dept.of Surgery,The 2nd Affiliated Hospital of Kunming Medical University,Kunming Yunnan ,China"
            },
            {
                "name": "TIAN Da-guang",
                "org": "Dept.of Surgery,The 2nd Affiliated Hospital of Kunming Medical University,Kunming Yunnan ,China"
            }
        ],
        "venue": "Journal of Kunming Medical University",
        "year": 2009
    },
    "4JyZffCP": {
        "id": "4JyZffCP",
        "title": "Establishment and Improvement of Rabbit Model of Partial Pancreas Transplantation from Living- related Donors",
        "abstract": "Objective To establish and improve the rabbit model of partial pancreas transplantation from living-related donors.Methods Donor surgery:The body,tail of pancreas and the spleen were taken out in the donor rabbit by splenic artery perfusion,ending donor surgery.Recipient surgery: The splenic vein was anastomosed with recipient’s splenic vein while the splenic artery was anastomosed with recipient’s splenic artery.Results 16 cases of pancreas transplantation were performed on rabbit,the successful rate of surgery for living donor was 100%,and the successful rate of the receptor was 94%(15/16),the blood glucose in recipients that survived over 3 d turned to normal range basically.Conclusion The rabbit model of partial pancreas transplantation from living-related donors we established and improved is useful for relevant research in pancreas transplantation.",
        "keywords": [
            "Transplantation",
            "Model",
            "Pancreas",
            "Rabbit"
        ],
        "authors": [
            {
                "name": "LI Han-yu",
                "org": ")%%#1%%# Dept.of Hepatobiliary Surgery,The 2nd Affiliated Hospital of Kunming Medical University,Kunming Yunnan "
            },
            {
                "name": "XIAO Shu-feng",
                "org": " Dept.of Organ Transplantation,303 Hospital of PLA,Nanning Guangxi ,China)"
            },
            {
                "name": "ZHU Hong",
                "org": ")%%#1%%# Dept.of Hepatobiliary Surgery,The 2nd Affiliated Hospital of Kunming Medical University,Kunming Yunnan "
            },
            {
                "name": "LI Yong-zhi",
                "org": ")%%#1%%# Dept.of Hepatobiliary Surgery,The 2nd Affiliated Hospital of Kunming Medical University,Kunming Yunnan "
            },
            {
                "name": "TANG Bo",
                "org": ")%%#1%%# Dept.of Hepatobiliary Surgery,The 2nd Affiliated Hospital of Kunming Medical University,Kunming Yunnan "
            },
            {
                "name": "ZHANG Jie",
                "org": ")%%#1%%# Dept.of Hepatobiliary Surgery,The 2nd Affiliated Hospital of Kunming Medical University,Kunming Yunnan "
            }
        ],
        "venue": "Journal of Kunming Medical University",
        "year": 2009
    },
    "iekRdQug": {
        "id": "iekRdQug",
        "title": "The Prevention of Hepatitis B Reinfection and Recurrence after Liver Transplantation",
        "abstract": "Objective To explore the strategy for prevention of HBV recurrence and reinfection in patients with hepatitis B related liver diseases after liver transplantation.Methods 37 cases took Lamivudine before operation,hepatitis B immunoglobulin during operation,and both after operation,then we observed the results for 1 year post operation.Result A follow-up of 1 year showed that the reinfection rate of HBV was 16.2% and the recurrence rate of that was 5.4%.Conclusion HBIg and small dose lamivudine are effective to prevent HBV reinfection and recurrence in post-liver transplantation patients.",
        "keywords": [
            "Hepatitis B",
            "Hepatitis B immuoglobulin",
            "Lamivudine",
            "Liver transplantation"
        ],
        "authors": [
            {
                "name": "ZHU Hong",
                "org": ")%%#1%%#Dept.of Hepatobiliary Surgery,The 2nd Affiliated Hospital of Kunming Medical University,Kunming Yunnan "
            },
            {
                "name": "XIAO Shu-feng",
                "org": "Dept.of Organ Transplantation,303 Hospital of PLA,Giamgxo Nanning ,China)"
            },
            {
                "name": "LI Han-yu",
                "org": ")%%#1%%#Dept.of Hepatobiliary Surgery,The 2nd Affiliated Hospital of Kunming Medical University,Kunming Yunnan "
            },
            {
                "name": "LI Yong-zhi",
                "org": ")%%#1%%#Dept.of Hepatobiliary Surgery,The 2nd Affiliated Hospital of Kunming Medical University,Kunming Yunnan "
            },
            {
                "name": "TIAN Da-guang",
                "org": ")%%#1%%#Dept.of Hepatobiliary Surgery,The 2nd Affiliated Hospital of Kunming Medical University,Kunming Yunnan "
            },
            {
                "name": "ZHANG Jie",
                "org": ")%%#1%%#Dept.of Hepatobiliary Surgery,The 2nd Affiliated Hospital of Kunming Medical University,Kunming Yunnan "
            }
        ],
        "venue": "Journal of Kunming Medical University",
        "year": 2009
    },
    "nmHV7vMi": {
        "id": "nmHV7vMi",
        "title": "Research Advancement of Perforin and Granzyme B in Graft Rejection",
        "abstract": "The perforin and granzyme B are glucoproteins which are stored and secreted by the endochylema granules of cytotoxic effector cells and natural cell.The effector cells can bring about lethal effect to target cells.Perforin generates pores in target-cell membranes and causes cell death or produces a marked synergistic effect with granzyme B to induce apoptosis.The perforin and granzyme B could have a significant impact on adjusting immune response,and were correlated to viral infection,tumor and graft rejection.This paper reviews the present study status quo of the perforin and granzyme B in graft rejection.",
        "keywords": [
            "Perforin",
            "Reject reaction",
            "Cytotoxic T lymphocyte",
            "Granzyme"
        ],
        "authors": [
            {
                "name": "TANG Bo",
                "org": "Department of Hepatobiliary Surgery,the Second Affiliated Hospital of Kunming Medical College,Kunming ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Hepatobiliary Surgery,the Second Affiliated Hospital of Kunming Medical College,Kunming ,China"
            }
        ],
        "venue": "Medical Recapitulate",
        "year": 2009
    },
    "dMS8y3gJ": {
        "id": "dMS8y3gJ",
        "title": "Establishment of Canine Model of Simultaneous Pancreas- kidney Transplantation in 12 Pairs of Animals",
        "abstract": "Objective To establish canine model of the simultaneous pancreas-kidney transplantation(SPK),and to observe treatment about type 1 diabetic nephropathy.Methods 24 pairs of canine were divided into donors and recipients group randomly.Donor’s multiple organs were cut,including the whole pancreas,segment of duodenum,kidneys and spleen.Left lobe of pancreas was resected in recipients to establish the model of diabetes 1.The portal vein and abdominal aorta of donor was joined by end-to-side anastomosis to the right sleeve chip external iliac artery and vein respectively,the left renal arteriovenous was performed the end-to-side anastomosis between the left external iliac artery and vein of receptor respectively,duodenum and bladder anastomosis,didn’t carry out the the anti-rejection treatment was not used,the levels of blood glucose and urine amylase were measured in perioperative period,also histopathological examination was performed.Results 12 cases of recipients received pancreatoduodenal allotransplantation,2 cases died in each group(donor and recipient groups) for the accident of intraoperative anesthesia.The success rate of operation in recipients was 91.7%.Complications happened in 4 cases,including anastomotic artery thrombosis(16.7%) in 2 cases,vascular of graft torsion(8.3%) in 1 cases and duodenal necrosis(8.3%) in 1 cases.Among 10 recipients,function of endocrine and exocrine was basically normal,but rejection occurred gradually in graft kidney,duodenum and pancreas from 3 to 7 postoperative days,finally graft dysfunction caused recipients to did.Conclusion SPK model of canines is a feasible treatment to diabetic nephropathy,and a good surgical technique is the basic requirement of a successful SPK transplantation,technical complications and rejection are the main reasons for graft dysfunction.",
        "keywords": [
            "Type 1 diabetes",
            "SPK",
            "Canine",
            "Diabetic nephropath",
            "Animal model"
        ],
        "authors": [
            {
                "name": "ZHU Hong",
                "org": ")%%#1%%# Dept.of Hepatobiliary Surgery,The 2nd Affiliated Hospital of Kunming Medical University,Kunming Yunnan "
            },
            {
                "name": "LI Han-yu",
                "org": ")%%#1%%# Dept.of Hepatobiliary Surgery,The 2nd Affiliated Hospital of Kunming Medical University,Kunming Yunnan "
            },
            {
                "name": "LI Yong-zhi",
                "org": ")%%#1%%# Dept.of Hepatobiliary Surgery,The 2nd Affiliated Hospital of Kunming Medical University,Kunming Yunnan "
            },
            {
                "name": "XIAO Shu-feng",
                "org": " The Center of Organ Transplantation 303 Hospital of PLA,Nanning Guanxi ,China)"
            },
            {
                "name": "TANG Bo",
                "org": ")%%#1%%# Dept.of Hepatobiliary Surgery,The 2nd Affiliated Hospital of Kunming Medical University,Kunming Yunnan "
            },
            {
                "name": "ZHANG Jie",
                "org": ")%%#1%%# Dept.of Hepatobiliary Surgery,The 2nd Affiliated Hospital of Kunming Medical University,Kunming Yunnan "
            }
        ],
        "venue": "Journal of Kunming Medical University",
        "year": 2009
    },
    "G4qRgkNa": {
        "id": "G4qRgkNa",
        "title": "The Expression of FGF-20 and its Clinical Significance in the Tissues from Colorectal Cancer",
        "abstract": "Objective To explore the expression of FGF-20 and its clinical significance in the tissues from colorectal cancer.Methods The expression of FGF-20 was detected by Immunohistochemistry in 45 colorectal cancer tissues and 20 normal colorectal tissues.Results The expression rate of FGF-20 in the colorectal tissues was 77.78%,which was significantly higher than that in the normal colorectal tissues of 15% (P<0.01). The expression of FGF-20 in colorectal cancer was significantly correlated with the depth of invasion,lymph node metastasis and clinical stage (P<0.05)Conclusion FGF-20 may play an important role in the tumorigenesis and development of colorectal cancer. It might be a therapeutic target and a new prognostic factor in the patients with colorectal cancer.",
        "keywords": [
            "Fibroblast growth factor-20",
            "Colorectal cancer",
            "Immunohistochemistry"
        ],
        "authors": [
            {
                "name": "LIU Ping",
                "org": ",et al. Department of Colorectal Oncology,the Third Affiliated Hospital of Kunming Medical College,Tumor Hospital of Yunnan Province,Kunming,"
            },
            {
                "name": "LI Yun-feng",
                "org": ",et al. Department of Colorectal Oncology,the Third Affiliated Hospital of Kunming Medical College,Tumor Hospital of Yunnan Province,Kunming,"
            },
            {
                "name": "ZHANG Jie",
                "org": ",et al. Department of Colorectal Oncology,the Third Affiliated Hospital of Kunming Medical College,Tumor Hospital of Yunnan Province,Kunming,"
            }
        ],
        "venue": "The Practical Journal of Cancer",
        "year": 2009
    },
    "qJKvzVAp": {
        "id": "qJKvzVAp",
        "title": "Value of Thyroid Stimulating Hormone Inhibition Therapy in Differentiated Thyroid Carcinoma",
        "abstract": "Objective To investigate the value of thyroid stimulating hormone(TSH)inhibition therapy in postoperative patients with differentiated thyroid carcinoma.Methods One hundred and six patients with differentiated thyroid carcinoma after total or near-total thyroidectomy were divided into two groups:TSH inhibition therapy group and thyroid hormone replacement therapy group.The non-recurrence and(or)non-metastasis rate in two groups was analyzed retrospectively by Wilcoxon statistical analysis.Results The non-recurrence and(or)non-metastasis rate of 3-,5-and 10-year in TSH inhibition therapy group were 98.31%,92.41% and 75.45% respectively,and were higher than those(93.57%,84.18% and 52.06% respectively)in thyroid hormone replacement therapy group(P=0.046 5).Conclusion TSH inhibition therapy after total or near-total thyroidectomy may be an essential treatment for differentiated thyroid carcinoma patients.",
        "keywords": [
            "Recurrence rate",
            "Metastasis rate",
            "Thyroid stimulating hormone inhibition therapy",
            "Thyroid hormone replacement therapy",
            "Differentiated thyroid carcinoma"
        ],
        "authors": [
            {
                "name": "MA Jun-feng",
                "org": ".1.Department of Tumor,The Second Affiliated Hospital of Kunming Medical College,Kunming ,China"
            },
            {
                "name": "TANG Bo",
                "org": "Department of General Surgery,The Second Affiliated Hospital of Kunming Medical College,Kunming ,China"
            },
            {
                "name": "LI Tie-han",
                "org": "Department of General Surgery,The Second Affiliated Hospital of Kunming Medical College,Kunming ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of General Surgery,The Second Affiliated Hospital of Kunming Medical College,Kunming ,China"
            }
        ],
        "venue": "Chinese Journal of Bases and Clinics in General Surgery",
        "year": 2009
    },
    "iBTxStff": {
        "id": "iBTxStff",
        "title": "Effects of HGF and SAM on liver regeneration and liver function in cirrhotic rats after hepatectomy",
        "abstract": "Objective To comparatively investigate the protective effect of HGF and SAM on liver regeneration and liver function in cirrhotic rats after hepatectomy.Methods Liver cirrhosis of the rat was successfully induced by injection of CCL4.Then 30% partial hepatectomy was performed in all rats.Cirrhotic rats were divided into 4 groups,namely,cirrhotic group(normal saline 5 mL/d IM,n=16),HGF group(HGF 0.65 mg/(100 g·d) peritoneal injection,n=16),SAM group(SAM 20 mg/(kg·d) IM,n=16)and HGF+SAM group(HGF 0.65 mg/(100g·d),SAM 20 mg/(kg·d),n=16).Animals were sacrificed on the 15th post-operative day to take samples for detection of liver function(AST,ALT,ALB and TB).Liver tissues were also observed under light microscope and electron microscope.Results In HGF group,SAM group and HGF+SAM group,valus of AST,ALT and TB were decreased significantly as with cirrhotic group(P<0.05),and concentrations of ALB were increased significantly(P<0.05).Conclusions The study suggests that the liver function and regeneration of cirrhotic rats have impaired after partial hepatectomy.However HGF and SAM have the efficacy of enhancing liver regeneration and improving liver function.",
        "keywords": [
            "Hepatectomy",
            "SAM",
            "Liver Cirrhosis",
            "HGF",
            "Liver Regeneration"
        ],
        "authors": [
            {
                "name": "ZHU Hong",
                "org": "the First Department of Hepato-Biliary-Pancreatic Surgery,The Second Affiliated Hospital,Kunming Medical College,Kunming ,China"
            },
            {
                "name": "XIAO Shufeng",
                "org": "the First Department of Hepato-Biliary-Pancreatic Surgery,The Second Affiliated Hospital,Kunming Medical College,Kunming ,China"
            },
            {
                "name": "TIAN Daguang",
                "org": "the First Department of Hepato-Biliary-Pancreatic Surgery,The Second Affiliated Hospital,Kunming Medical College,Kunming ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "the First Department of Hepato-Biliary-Pancreatic Surgery,The Second Affiliated Hospital,Kunming Medical College,Kunming ,China"
            },
            {
                "name": "TANG Bo",
                "org": "the First Department of Hepato-Biliary-Pancreatic Surgery,The Second Affiliated Hospital,Kunming Medical College,Kunming ,China"
            },
            {
                "name": "LI Hanyu",
                "org": "the First Department of Hepato-Biliary-Pancreatic Surgery,The Second Affiliated Hospital,Kunming Medical College,Kunming ,China"
            },
            {
                "name": "LI Yongzhi",
                "org": "the First Department of Hepato-Biliary-Pancreatic Surgery,The Second Affiliated Hospital,Kunming Medical College,Kunming ,China"
            }
        ],
        "venue": "Chinese Journal of General Surgery",
        "year": 2009
    },
    "RV6MOECa": {
        "id": "RV6MOECa",
        "title": "The Operation Curve of Anatomic Hepatectomy with Glissonean Pedicle Transection Method for Hepatic Resection",
        "abstract": "Objective To study the operation curve of Glissonean pedicle transection method for hepatic resection,and provide experiences for its clinic application.Mehods From February 2009 to December 2010,a retrospective study was done on 31 cases with Glissonean pedicle transection method for hepatic resection.The curves of operative time-consuming,the volume of intraoperative blood loss,the volume of blood transfusion and liver function were analyzed with the accumulating cases.Results A negative correlation was found between the above indexes and accumulating cases.These indexes were better and better for every 10 cases from the first case to the thirtieth case.The radical tumor resection rate was 81.8% for 31 cases.The actuarial survival rates after18 months was 100% in radical resection cases,the recurrence rate was 4.5%,and the survival rates was 90.9% for overall 31 cases.The liver enzymologic indexes for cases with malignant and benigh tumor recovered to normal levels in 2 weeks,and AFP levels of HCC patients recovered to normal levels in 3 weeks after operation.Conclusion Glissonean pedicle transection method for hepatic resection,based on the reasonable three segments of liver anatomy,is safe and effective in dealing with liver tumor and the top-ten cases are most important for mastering Glissonean pedicle transection method for hepatic resection.",
        "keywords": [
            "Anatomic liver resection",
            "Glissonean pedicle transection method for hepatic resection",
            "Operation curve"
        ],
        "authors": [
            {
                "name": "TANG Ji-hong",
                "org": ")%%#1%%#Dept.of The 1st Hepatobiliary Surgery,Tthe 2nd Affiliated Hospital of Kunming Medical University,Kunming Yunnan "
            },
            {
                "name": "FU bi-mang",
                "org": ")%%#1%%#Dept.of The 1st Hepatobiliary Surgery,Tthe 2nd Affiliated Hospital of Kunming Medical University,Kunming Yunnan "
            },
            {
                "name": "Tang Bo",
                "org": ")%%#1%%#Dept.of The 1st Hepatobiliary Surgery,Tthe 2nd Affiliated Hospital of Kunming Medical University,Kunming Yunnan "
            },
            {
                "name": "Li Han-yu",
                "org": "Dept.of Hepatobiliary Surgery,The 4th Affiliated Hospital of Kunming Medical University,Kunming Yunnan ,China)"
            },
            {
                "name": "Zhu Hong",
                "org": ")%%#1%%#Dept.of The 1st Hepatobiliary Surgery,Tthe 2nd Affiliated Hospital of Kunming Medical University,Kunming Yunnan "
            },
            {
                "name": "ZHANG Jie",
                "org": ")%%#1%%#Dept.of The 1st Hepatobiliary Surgery,Tthe 2nd Affiliated Hospital of Kunming Medical University,Kunming Yunnan "
            }
        ],
        "venue": "Journal of Kunming Medical University",
        "year": 2010
    },
    "OD1USnW7": {
        "id": "OD1USnW7",
        "title": "The diagnosis and treatment of portal vein thrombosis after splenectomy",
        "abstract": "Objective To study the etiological factors and the treatment methods of portal vein thrombosis (PVT) and mesenteric venous thrombosis (MVT) after splenectomy. Methods Clinical materials of 12 patients with PVT and MVT after splenectomy were analyzed retrospectively. Results Venous thrombosis occurred in 12 of 280 post-splenectomy patients (4.3%) including nine patients with PVT(4.3%)and three patients with MVT(1.1%). All of the PVT patients had leukocytosis,increase platelet count,positive D-dimer and abnormal thromboplastic function. PVT and MVT were discovered with color ultrasonography,CT,and MRI in nine patients,with superior mesenteric artery angiography in one case,and at exploratory laparotomy because of acute intestinal obstruction in two cases. Nine patients were cured by anti-coagulation and thrombolytic therapy. Two MVT cases had small intestinal necrosis underwent intestioal resection and anastomosis,postoperative systemic anticoagulation and thrombolytic therapy,and were cured. One case of acute PVT thrombosis with progression to intrahepatic portal vein,died of liver failure. Conclusions Post-splenectomy portal system thrombosis is related with many factors. Early diagnosis and prompt anticoagulant therapy has an important impact on prognosis. If results of non-operative therapy are not satisfactory,prompt surgical therapy is advocated.",
        "keywords": [
            "Splenectomy/adv eff",
            "Mesenteric Vein Thrombosis/ther",
            "Portal Vein Thrombosis/ther"
        ],
        "authors": [
            {
                "name": "LI Tiehan",
                "org": "Department of Hepatobiliary & Pancreatic Surgery,the Second Affiliated Hospital,Kunming Medical College,Kunming ,China"
            },
            {
                "name": "TANG Bo",
                "org": "Department of Hepatobiliary & Pancreatic Surgery,the Second Affiliated Hospital,Kunming Medical College,Kunming ,China"
            },
            {
                "name": "TANG Jihong",
                "org": "Department of Hepatobiliary & Pancreatic Surgery,the Second Affiliated Hospital,Kunming Medical College,Kunming ,China"
            },
            {
                "name": "FU Bimang",
                "org": "Department of Hepatobiliary & Pancreatic Surgery,the Second Affiliated Hospital,Kunming Medical College,Kunming ,China"
            },
            {
                "name": "MA Junfeng",
                "org": "Department of Hepatobiliary & Pancreatic Surgery,the Second Affiliated Hospital,Kunming Medical College,Kunming ,China"
            },
            {
                "name": "ZHU Hong",
                "org": "Department of Hepatobiliary & Pancreatic Surgery,the Second Affiliated Hospital,Kunming Medical College,Kunming ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Hepatobiliary & Pancreatic Surgery,the Second Affiliated Hospital,Kunming Medical College,Kunming ,China"
            }
        ],
        "venue": "Chinese Journal of General Surgery",
        "year": 2010
    },
    "et8iWTf5": {
        "id": "et8iWTf5",
        "title": "Evaluation of the clinical effect of the routine hepatectomy after the estabitishment of model of simulating hepatectomy with 256 iCT images",
        "abstract": "Objective To study the effect and feasibility of accurate liver resection guided by model of liver three dimensional reconstruction(3D) and model of simulating hepatectomy with iCT images.Methods Forty-seven patients suffered from liver cancer and undergone liver resection,hospitalized from Jun.2008 to Dec.2009 were divided into iCT group(n=23) and routine group(n=24).Pre-operation,the volume and morphous of total liver were reconstructed with 3D using images of iCT in iCT group patients,and simulating hepatectomy models were built according the principle of liver segments dissection.Liver resection practice was guided by the 3D images and simulating hepatectomy models.Patients in routine group underwent liver resection with two-dimension images.Results Compared with routine group,the volume of intraoperative blood loss,blood transfusion,and operative duration,in iCT group were remarkably less than that in routine group(P<0.05),the rate of blood transfusion was not different(P>0.05) between two groups.Recovery of ALT post-operation in iCT group was more better than that in routine group(P<0.05),while the recovery of alpha-fetoprotein(AFP) and total bilirubin(TB) were not different remarkably between the two groups(P>0.05).Patients were followed up from 3~18(12.6±2.3)months.Survival rate of iCT group(100%) was significant higher than that in routine group(78.3%)(P=0.000);while carcinoma recurrence rate in iCT group(18.1%) was more less than that in routine group(47.8%)(P=0.035).Conclusion Liver resection for the treatment of hepatocellular carcinoma(HCC),guided by 3D reconstruction and simulating hepatectomy model,will promote the clinic treating effect of HCC.",
        "keywords": [
            "accurate liver resection",
            "three dimension(3D) reconstruction",
            "intelligent CT(iCT)",
            "simulating hepatectomy model"
        ],
        "authors": [
            {
                "name": "TANG Ji-hong",
                "org": "urgery Department,the Second Affiliated Hospital of Kunming Medical University,Kunming "
            },
            {
                "name": "FU Bi-mang",
                "org": "urgery Department,the Second Affiliated Hospital of Kunming Medical University,Kunming "
            },
            {
                "name": "ZHANG Jie",
                "org": "urgery Department,the Second Affiliated Hospital of Kunming Medical University,Kunming "
            },
            {
                "name": "y S",
                "org": "urgery Department,the Second Affiliated Hospital of Kunming Medical University,Kunming "
            }
        ],
        "venue": "Journal of Hepatopancreatobiliary Surgery",
        "year": 2010
    },
    "aw1cW8UW": {
        "id": "aw1cW8UW",
        "title": "Effect of Alanl-glutamine on Postoperative Immunofunction of Critically Surgical Patients",
        "abstract": "Objective To investigate the effect of alanyl-glutamine (Ala-Gln) on the postoperative immune function of critically surgical patients.Methods Fifty-four critically surgical patients with APACHE Ⅱ score>12 were randomly divided into treatment group and control group.All patients in the two groups were treated with with routine surgical treatment combined with parenteral nutrition and observed for 7 days.Patients in the control group were given general parenteral nutrition (PN) and patients in the treatment group were treated with L-glutamine as substrate parenteral nutrition support immunization.The albumin (ALB),prealbumin (PAB),and transferrin (TRF),as well as IgG,IgA,and IgMand the T-lymphocyte subsets CD3,CD4,and CD8 of patients in the two groups were detected before operation and 7 days after postoperative nutritional support.Results The ALB,PAB,and TRF of patients in the treatment group were significantly increased 7 days after nutritional support with alanyl-glutamine (P <0.05),while the ALB,PAB and TRF of patients in the control group had no no significant difference before and after nutritional support (P>0.05).The increase of PAB in the treatment group was significantly higher than that in the control group (P<0.05).The IgA,IgG and IgM of patients in the treatment group after nutritional support were higher than the control group and before nutritional support (P<0.05).The T-lymphocyte subsets CD4 percentage and CD4/CD8 values of patients in the treatment group after nutritional support were higher than before nutritional support and the control group (P<0.05). Conclusion The strenghthed parenteral nutrient of Ala-Gln can increase the postoperative immunoglobulin and number of lymphocytes of critically surgical patients,thus improve the immunofunction of the surgical patients.",
        "keywords": [
            "Glutamine",
            "Immune regulation",
            "Surgical procedures"
        ],
        "authors": [
            {
                "name": "YE Ji-yun",
                "org": ") %%#1%%# Yunnan Medical College,Kunming Yunnan "
            },
            {
                "name": "HUANG Jie",
                "org": " Dept. of Hepato-biliary Surgery,The 2nd Affiliated Hospital of Kunming Medical University,Kunming Yunnan ,China)"
            },
            {
                "name": "TIAN Da-guang",
                "org": " Dept. of Hepato-biliary Surgery,The 2nd Affiliated Hospital of Kunming Medical University,Kunming Yunnan ,China)"
            },
            {
                "name": "ZHANG Jie",
                "org": " Dept. of Hepato-biliary Surgery,The 2nd Affiliated Hospital of Kunming Medical University,Kunming Yunnan ,China)"
            }
        ],
        "venue": "Journal of Kunming Medical University",
        "year": 2010
    },
    "b9eGhMX6": {
        "id": "b9eGhMX6",
        "title": "Three-dimensional CT angiography for preoperative evaluation of patients undergoing hepatic resection using the Glissonean pedicle transection method",
        "abstract": "AIM:To investigate the use of three-dimensional CT angiography for preoperative evaluation of patients undergoing hepatic resection using the Glissonean pedicle transection method.METHODS:The image data for 23 patients undergoing CT angiography with a Philips 256-slice Intelligent CT Scanner were analyzed with Philips brilliance software.Three-dimensional and maximum intensity projection(MIP)image reconstruction was performed.Based on the reconstructed data,liver segment resection models were developed to evaluate the possibility of preoperative virtual liver segment resection.RESULTS:Based on three-dimensional reconstruction data,the average liver volume and weight,excluding the portal vein and hepatic vein,were 1 219 mL ± 191 mL and 1 451 g ± 227 g,respectively.The portal vein could be divided into four types:I,II,III and IV.Patients with types I and II portal vein were fit for hepatic resection using the Glissonean pedicle transection method.There is no significant difference in the weight of resected liver between virtual and actual hepatectomy(P > 0.05).CONCLUSION:Three-dimensional CT angiography is a good strategy for preoperative evaluation of patients undergoing hepatic resection using the Glissonean pedicle transection method.",
        "keywords": [
            "Glissonean pedicle transaction method for hepatic resection",
            "Liver volume",
            "Portal vein",
            "Philips 256-slice Intelligent CT Scanner",
            "Three-dimensional reconstruction"
        ],
        "authors": [
            {
                "name": "Ji-Hong Tang",
                "org": ",Department of Organ Transplantation,the First Affiliated Hospital of Sun Yat-sen University,Guangzhou ,Guangdong Province,China"
            },
            {
                "name": "Bi-Mang Fu",
                "org": ",Department of Organ Transplantation,the First Affiliated Hospital of Sun Yat-sen University,Guangzhou ,Guangdong Province,China"
            },
            {
                "name": "Hong Zhu",
                "org": ",Department of Organ Transplantation,the First Affiliated Hospital of Sun Yat-sen University,Guangzhou ,Guangdong Province,China"
            },
            {
                "name": "Bo Tang",
                "org": ",Department of Organ Transplantation,the First Affiliated Hospital of Sun Yat-sen University,Guangzhou ,Guangdong Province,China"
            },
            {
                "name": "Yong Sun",
                "org": ",Department of Organ Transplantation,the First Affiliated Hospital of Sun Yat-sen University,Guangzhou ,Guangdong Province,China"
            },
            {
                "name": "Jie Zhang",
                "org": ",Department of Organ Transplantation,the First Affiliated Hospital of Sun Yat-sen University,Guangzhou ,Guangdong Province,China"
            },
            {
                "name": "Da-Kuan Yang",
                "org": ",Department of Organ Transplantation,the First Affiliated Hospital of Sun Yat-sen University,Guangzhou ,Guangdong Province,China"
            },
            {
                "name": "Xiao-Shun He",
                "org": ",Department of Organ Transplantation,the First Affiliated Hospital of Sun Yat-sen University,Guangzhou ,Guangdong Province,China"
            }
        ],
        "venue": "World Chinese Journal of Digestology",
        "year": 2010
    },
    "RDkqYHgt": {
        "id": "RDkqYHgt",
        "title": "Establishment and Evaluation of A Modified Piggyback Orthotopic Liver Transplantation Model",
        "abstract": "Objective To establish a stable and replicable large animal model of liver transplantation.Methods Forty Adult male Japanese white rabbits,weighing(3.0±0.5)kg,the donor rabbits were randomly divided into 2 groups,A group:graft preservation time was less than 2 hours,B group:graft preservation was time more than 4 hours.The rabbit liver transplantation was completed according to allograft piggyback.Results The surgical success rate was 85.0%.The median survival time of rabbist in A group was 16.0 days;but that of rabbist in B group was 6.4 days.Conclusion Rabbit improved piggyback liver transplantation model is a stable model which is easily copied and is a large ideal animal model of liver transplantation.",
        "keywords": [
            "Model",
            "Rabbit",
            "Piggyback",
            "Liver transplantation"
        ],
        "authors": [
            {
                "name": "ZHU Hong",
                "org": "Dept.of Hepatobiliaropancreatic Surgery,The Institute of Organtrans Plantation,The 2nd Affiliated Hospital of Kunming Medical University,Kunming Yunnan ,China"
            },
            {
                "name": "YANG Da-kuan",
                "org": "Dept.of Hepatobiliaropancreatic Surgery,The Institute of Organtrans Plantation,The 2nd Affiliated Hospital of Kunming Medical University,Kunming Yunnan ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Dept.of Hepatobiliaropancreatic Surgery,The Institute of Organtrans Plantation,The 2nd Affiliated Hospital of Kunming Medical University,Kunming Yunnan ,China"
            },
            {
                "name": "TIAN Da-guang",
                "org": "Dept.of Hepatobiliaropancreatic Surgery,The Institute of Organtrans Plantation,The 2nd Affiliated Hospital of Kunming Medical University,Kunming Yunnan ,China"
            },
            {
                "name": "YU Sheng-feng",
                "org": "Dept.of Hepatobiliaropancreatic Surgery,The Institute of Organtrans Plantation,The 2nd Affiliated Hospital of Kunming Medical University,Kunming Yunnan ,China"
            },
            {
                "name": "TANG Bo",
                "org": "Dept.of Hepatobiliaropancreatic Surgery,The Institute of Organtrans Plantation,The 2nd Affiliated Hospital of Kunming Medical University,Kunming Yunnan ,China"
            }
        ],
        "venue": "Journal of Kunming Medical University",
        "year": 2011
    },
    "uvBuIZYF": {
        "id": "uvBuIZYF",
        "title": "Clinical effects of anatomic hepatectomy with Cavitron ultrasonic surgical aspirator using optimized parameter settings",
        "abstract": "AIM:To evaluate the clinical effects of anatomic hepatectomy with Cavitron ultrasonic surgical aspirator(CUSA)using optimized parameter settings.METHODS:Thirty-one patients with spaceoccupying lesions of the liver who underwent hepatectomy with CUSA were divided into two groups:patients using recommended parameters for CUSA(control group,n=10)and those using optimized parameters(optimization group,n=21).Total blood loss,blood transfusion,operative time,and recovery of liver func-tion after operation were compared between the two groups.RESULTS:All the patients recovered in 4 weeks after operation.Radical treatment was achieved in 90%of patients using recommended parameters and in 87.5%of those using optimized ones,with no significant different between the two groups.Total blood loss,blood transfusion,operative time,and recovery of liver function after operation were better in the optimization group than in the control group(3.8 h±0.8 h vs 6.2 h± 1.9 h;1 150 mL±460 mL vs 2 900 mL±510 mL;530 mL±300 mL vs 1 760 mL±1 700 mL,all P< 0.05).The mean amount of abdominal drainage in 24 h after operation was not remarkably different between the two groups.CONCLUSION:Using optimized parameters for CUSA can improve the clinical effects and efficiency of anatomic hepatectomy for patients with space-occupying lesions of the liver.",
        "keywords": [
            "Optimized parameter settings",
            "Cavitron ultrasonic surgical aspirator",
            "Anatomical hepatectomy",
            "Efficiency of hepatectomy"
        ],
        "authors": [
            {
                "name": "Ji-Hong Tang",
                "org": ",Department of Hepatobiliary Surgery,the Fourth Affiliated Hospital of Kunming Medical University,Kunming ,Yunnan Province,China"
            },
            {
                "name": "Bi-Mang Fu",
                "org": ",Department of Hepatobiliary Surgery,the Fourth Affiliated Hospital of Kunming Medical University,Kunming ,Yunnan Province,China"
            },
            {
                "name": "Bo Tang",
                "org": ",Department of Hepatobiliary Surgery,the Fourth Affiliated Hospital of Kunming Medical University,Kunming ,Yunnan Province,China"
            },
            {
                "name": "Han-Yu Li",
                "org": ",Department of Hepatobiliary Surgery,the Fourth Affiliated Hospital of Kunming Medical University,Kunming ,Yunnan Province,China"
            },
            {
                "name": "Hong Zhu",
                "org": ",Department of Hepatobiliary Surgery,the Fourth Affiliated Hospital of Kunming Medical University,Kunming ,Yunnan Province,China"
            },
            {
                "name": "TieHan Li",
                "org": ",Department of Hepatobiliary Surgery,the Fourth Affiliated Hospital of Kunming Medical University,Kunming ,Yunnan Province,China"
            },
            {
                "name": "Feng Liu",
                "org": ",Department of Hepatobiliary Surgery,the Fourth Affiliated Hospital of Kunming Medical University,Kunming ,Yunnan Province,China"
            },
            {
                "name": "Jie Zhang",
                "org": ",Department of Hepatobiliary Surgery,the Fourth Affiliated Hospital of Kunming Medical University,Kunming ,Yunnan Province,China"
            }
        ],
        "venue": "World Chinese Journal of Digestology",
        "year": 2011
    },
    "cd0llmFk": {
        "id": "cd0llmFk",
        "title": "Research Progress in Quantitative Liver Function Tests",
        "abstract": "Liver functional reserve and routine quantitative evaluation of liver function are clinically implicated in patients scheduled for liver surgery.At present,a variety of routine quantitative liver function tests are in place,including arterial blood ketone body ratio test,indocyanine green test,oral glucose tolerance test,glucagon loading test,lidocaine metabolism test,and tryptophan tolerance test.This article briefly reviews preoperative and postoperative liver function evaluations and contributing factors.",
        "keywords": [
            "Quantitative test",
            "Liver function",
            "Contributing factor"
        ],
        "authors": [
            {
                "name": "YU Sheng-feng",
                "org": "Department of Hepatobiliary Surgery,the Second Affiliated Hospital of Kunming Medical College,Kunming ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Hepatobiliary Surgery,the Second Affiliated Hospital of Kunming Medical College,Kunming ,China"
            },
            {
                "name": "FU Bi-mang",
                "org": "Department of Hepatobiliary Surgery,the Second Affiliated Hospital of Kunming Medical College,Kunming ,China"
            }
        ],
        "venue": "Medical Recapitulate",
        "year": 2011
    },
    "hIkCEqq9": {
        "id": "hIkCEqq9",
        "title": "Investigating Optimal Types of Iatrogenic Bile Duct Injury——A Retrospective Analysis of Clinical Treatment With 52 Cases",
        "abstract": "Objective To analyze the types and treatment of iatrogenic bile duct injury in order to summarize the clinical experience of treating iatrogenic bile duct injury.Methods Bile duct injury were divided into Ⅰ,Ⅱ,Ⅲ and Ⅳ types optimized by authors according to published papers.Based on this optimal types,the clinical treating experiences of 52 patients suffered from iatrogenic bile duct injury were investigated retrospectively.Results Common bile duct and common hepatic duct were the most injuring location,and the injuring rate was 50.0% and 30.8%,respectively.The most injuring type(Ⅰ)was sharp instrument injury which wounds was ≤ 2 mm,followed by the type(Ⅲ)which bile defect was ≥1/3 of bile duct circumference,and the injuring rate was 40.4% and 42.3%,respectively.Bile duct injury incidence was not significant deviation between LC and OC.However,the most bile injure in OC was type Ⅰand the rate was 54.2%;while the most injuring type in LC was type Ⅲ and the was 59.1%.Conclusion The optimal bile duct injury types are feasible and practical for guiding treatment of iatrogenic bile duct injury.",
        "keywords": [
            "Investigation",
            "Retrospective analysis.",
            "Iatrogenic bile duct injury",
            "Optimal types"
        ],
        "authors": [
            {
                "name": "FU Bi-mang",
                "org": "The 1st Department of Hepatobiliary Surgery,The 2nd Affiliated Hospital of Kunming Medical University,Kunming Yunnan ,China"
            },
            {
                "name": "TANG Ji-hong",
                "org": "The 1st Department of Hepatobiliary Surgery,The 2nd Affiliated Hospital of Kunming Medical University,Kunming Yunnan ,China"
            },
            {
                "name": "TANG Bo",
                "org": "The 1st Department of Hepatobiliary Surgery,The 2nd Affiliated Hospital of Kunming Medical University,Kunming Yunnan ,China"
            },
            {
                "name": "DONG Li-ying",
                "org": "The 1st Department of Hepatobiliary Surgery,The 2nd Affiliated Hospital of Kunming Medical University,Kunming Yunnan ,China"
            },
            {
                "name": "HU Ming-dao",
                "org": "The 1st Department of Hepatobiliary Surgery,The 2nd Affiliated Hospital of Kunming Medical University,Kunming Yunnan ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "The 1st Department of Hepatobiliary Surgery,The 2nd Affiliated Hospital of Kunming Medical University,Kunming Yunnan ,China"
            }
        ],
        "venue": "Journal of Kunming Medical University",
        "year": 2011
    },
    "oOgcGOGZ": {
        "id": "oOgcGOGZ",
        "title": "Hepatic functional reserve in patients with chronic hepatic injury: Evaluation by MELD scoring system",
        "abstract": "Objective To explore the value of MELD scoring system in assessing hepatic functional reserve in patients with chronic hepatic injury.Methods Retrospective analysis of the preoperative MELD scores of 38 patients with chronic hepatic injury undergoing liver transplantation was made,the quantitative values of liver fibrosis by computer-assisted digital image analysis was evaluated after operation,and the correlation between the MELD score and the percentage of liver fibrosis was analyzed.Results A positive linear correlation was found between MELD score and the percentage of hepatic fibrosis in patients with chronic hepatic injury.In the Child-Pugh A,B and C groups,the MELD score had significant difference(P<0.01).Conclusions MELD scoring system can be used to predict the hepatic functional reserve in patients with chronic hepatic injury.",
        "keywords": [
            "MELD Scoring Systems",
            "Hepatic Functional Reserve",
            "Chronic Hepatic Injury",
            "Liver/pathol"
        ],
        "authors": [
            {
                "name": "HUANG Jie",
                "org": "Department of Minimal Invasive Surgery,the Second Affiliated Hospital,Kunming Medical College,Kunming ,China"
            },
            {
                "name": "SUN Min",
                "org": "Department of Minimal Invasive Surgery,the Second Affiliated Hospital,Kunming Medical College,Kunming ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Minimal Invasive Surgery,the Second Affiliated Hospital,Kunming Medical College,Kunming ,China"
            }
        ],
        "venue": "Chinese Journal of General Surgery",
        "year": 2011
    },
    "5SjZ0fHE": {
        "id": "5SjZ0fHE",
        "title": "Using 256 Slice Intelligent CT Angiography of Portal Vein System with Three Dimensional Reconstruction to Guide Glissonean Pedicle Transection Method for Hepatic Resection",
        "abstract": "Purpose To study the anatomic types of intrahepatic portal veinsusing 256 slice Intelligent CT Angiography and to provide a roadmap for hepatic resection. Materials and Methods Based on three-phase liver imaging in 163 patients using Philips 256 Slice Intelligent CT scanner and Philips Brilliance Workspace Portal software, three-dimensional (3D) reconstruction of liver volume and portal vein was performed.The portal veins were classified according to the requirement of Glissonean pedicle transection method for hepatic resection. Results Portal veins could be classified into 4 types: regular (typeⅠ, 41.7%); left-middle-right (typeⅡ, 47.3%) withsimilarleft, middle and right branches; left-right (typeⅢ, 9.8%) showing equal left and right branches and special (typeⅣ, 1.2%). The diameters of main portal vein among the four types showed no statistical difference (P>0.05). Diameters of the first class branches in type II portal veinswere not statistically different (P>0.05); while in typeⅠ,the right branch of the first class branches was significantly bigger than the left branch (P<0.05), but the diameter of right anterior hepatic lobe and left main portal vein showed no statistical difference (P>0.05). The volume of the left, middle and right hepatic lobes in each type accounted for about 1/3 of total liver volume. Conclusion Glissonean pedicle transection method for hepatic resection is preferred in about 89% of patients with types I and II portal veins.For 11% of patients, the risk of vascular injuries is high.",
        "keywords": [
            "regional",
            "three-dimensional",
            "Hepatectomy",
            "X-ray computed",
            "Tomography",
            "Imaging",
            "Anatomy"
        ],
        "authors": [
            {
                "name": "FU Bimang",
                "org": " Department of Radiological Medicine, the Second Affiliated Hospital of Kunming Medical College, Kunming, Yunnan "
            },
            {
                "name": "TANG Jihong",
                "org": " Department of Radiological Medicine, the Second Affiliated Hospital of Kunming Medical College, Kunming, Yunnan "
            },
            {
                "name": "SUN Yong",
                "org": " Department of Radiological Medicine, the Second Affiliated Hospital of Kunming Medical College, Kunming, Yunnan "
            },
            {
                "name": "ZHANG Jie",
                "org": " Department of Radiological Medicine, the Second Affiliated Hospital of Kunming Medical College, Kunming, Yunnan "
            },
            {
                "name": "HU Mingdao",
                "org": " Department of Radiological Medicine, the Second Affiliated Hospital of Kunming Medical College, Kunming, Yunnan "
            },
            {
                "name": "YANG Dakuan",
                "org": " Department of Radiological Medicine, the Second Affiliated Hospital of Kunming Medical College, Kunming, Yunnan "
            },
            {
                "name": "HE Xiaoshun",
                "org": " Department of Radiological Medicine, the Second Affiliated Hospital of Kunming Medical College, Kunming, Yunnan "
            },
            {
                "name": "HUANG Jiefu",
                "org": " Department of Radiological Medicine, the Second Affiliated Hospital of Kunming Medical College, Kunming, Yunnan "
            }
        ],
        "venue": "Chinese Journal of Medical Imaging",
        "year": 2011
    },
    "oVNOdFUe": {
        "id": "oVNOdFUe",
        "title": "Monitoring of liver cell metabolism in early transplantation with the multi parameter system biosensor neurotrend-7",
        "abstract": "BACKGROUND:At present, various monitoring equipments have been used in graft early monitoring, but there is no way to continuous monitoring transplant liver cell metabolic changes to reflect the graft internal environment changes. OBJECTIVE:To explore continuous monitoring of liver cell metabolism with multi parameter system biosensor (Neurotrend-7), and to provide the basis for the liver hypofunction after transplantation in early stage. METHODS:A total of 24 healthy, adult, male, New Zealand, White rabbits were divided into 3 groups:control group, experimental group 1, and experimental group 2. Control group (n=4):They were treated with buried oxygen metabolism monitoring sensor of liver tissue when abdomen was opened, and abdomen was closed, after the specimen drawn. Multi parameter system biosensor probe was inserted into liver after liver transplantation between experimental group 1 and experimental group 2. Ten cases of rabbits underwent the liver transplantation, for the liver retention time was lesser than 2 hours in experimental group 1; 4 cases of rabbits underwent the liver transplantation, for the liver retention time was more than 4 hours in experimental group 2. Before transplantation and 1, 3, 5 days after transplantation, the changes of the pH, PCO2, and PO2 value in liver tissue were continually monitored, and PaO2, PaCO2, and arterial blood gas (ABG) pH value were measured. At the same time, the liver tissue cut in the corresponding points was observed under the optical microscope and electron microscope. RESULTS AND CONCLUSION:PO2 value of liver tissue in experimental group 2 was significantly lower than that in experimental group 1 (P < 0.05), and gradually decreased with the time. However, PCO2 value of liver tissue in experimental group 2 at each time was significantly higher than that in experimental group 1 (P < 0.05), and gradually increased with the time. PH value of liver tissue in experimental group 2 at each time was lower than that in experimental group 1 (P < 0.05). It is indicated that liver function is serious adverse and transplant is non-function. The PO2 and PaO2 were positive correlation;however, PCO2 and PaCO2 were not obvious relevance. Also, the pH value and ABG pH value were not obvious relevance. Changes are similar to the histology inspection. It suggested that multi parameter system biosensor (Neurotrend-7) can discover liver hypofunction after transplantation at early stage and observes its evolution rule, to guide early prevention and the treatment in clinic, it also can provides the accurate data for clinical application in the liver surgery and organ transplantation field.",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Tang Ji-hong",
                "org": "Kunming Medical College(Kunming Medical College),Kunming,China"
            },
            {
                "name": "Bo Tang",
                "org": "Kunming Medical College(Kunming Medical College),Kunming,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Kunming Medical College(Kunming Medical College),Kunming,China"
            },
            {
                "name": "Yang Da-kuan",
                "org": "Kunming Medical College(Kunming Medical College),Kunming,China"
            },
            {
                "name": "Da Guang Tian",
                "org": "Kunming Medical College(Kunming Medical College),Kunming,China"
            },
            {
                "name": "Fu Bi-mang",
                "org": "Kunming Medical College(Kunming Medical College),Kunming,China"
            },
            {
                "name": "Li Han-yu",
                "org": "Second People's Hospital of Yunnan Province(The Second People's Hospital of Yunnan Province,Second People's Hospital of Yunnan Province),Kunming,China"
            },
            {
                "name": "Yu Sheng-feng",
                "org": "Kunming Medical College(Kunming Medical College),Kunming,China"
            },
            {
                "name": "Hong Zhu",
                "org": "Kunming Medical College(Kunming Medical College),Kunming,China"
            }
        ],
        "venue": "Journal of Clinical Rehabilitative Tissue Engineering Research",
        "year": 2011
    },
    "k0CAKu7V": {
        "id": "k0CAKu7V",
        "title": "Progress of BSE and nvCJD researches",
        "abstract": "Prions are transmissible protein particles whicharefree of nucleic acids,and can causethe deposition of dena-tured proteinin mammalian central nervous system.Prions replicate themselvesthrough conformational change fromcellu-lar form(PrPC)to scrapieform(PrPSc).Thetwo proteins with different conformation,PrPCand PrPSc,are encoded bythesame gene.Such a modificationinvolvesthe secondary andtertiarystructure of the protein while the amino acid sequenceremains unchanged.The author reviews many aspects of bovine spongiformencephalopathy(BSE)and newvariant Creu-tzfeldt-Jakob disease(nvCJD) covering etology,structure,diagnosis and prevention as well as treatment.",
        "keywords": [
            "BSE",
            "structure",
            "prion",
            "nvCJD"
        ],
        "authors": [
            {
                "name": "CHEN Hao-tai",
                "org": "The Key Laboratory of Animal Virology of the Ministry of Agriculture,Lanzhou Veterinary Research Institute,Chinese Acedemyof Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "The Key Laboratory of Animal Virology of the Ministry of Agriculture,Lanzhou Veterinary Research Institute,Chinese Acedemyof Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "LIU Yong-sheng",
                "org": "The Key Laboratory of Animal Virology of the Ministry of Agriculture,Lanzhou Veterinary Research Institute,Chinese Acedemyof Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "WU Run",
                "org": "The Key Laboratory of Animal Virology of the Ministry of Agriculture,Lanzhou Veterinary Research Institute,Chinese Acedemyof Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "LIU Xiang-tao",
                "org": "The Key Laboratory of Animal Virology of the Ministry of Agriculture,Lanzhou Veterinary Research Institute,Chinese Acedemyof Agricultural Sciences,Lanzhou ,China"
            }
        ],
        "venue": "Basic Medical Sciences and Clinics",
        "year": 2005
    },
    "KbhHJXOP": {
        "id": "KbhHJXOP",
        "title": "Cloning and prokaryotic expression of human prion gene",
        "abstract": "The open reading frame (ORF) of prion protein gene,Prnp,was amplified by PCR using total DNA extracted from human blood as template. The PCR product was ligated with pMD-18T vector and then transformed into E. coli JM109. The recombinant plasmid was sequenced and analyzed with Blast software. It shared 99.6 % homology at their nucleotide level and 99.8 % identity at deduced amino acid level with the corresponding sequences deposited in Genbank. The gene encoding mature human prion protein was cloned into pET-30a(+) vector and then transformed by electroporation into E. coli BL21(DE3) competent cells. The expected protein was expressed in E. coli BL21(DE3) harboring the recombinant plasmid pET-homPrP induced by 1.0 mmol/L IPTG at 37 ℃. The expressed fusion protein was purified by Ni—NTA affinity resin according to the manufacture's directions. SDS—PAGE analysis showed that the fusion protein accounted for 20 %-25 % of the total bacterial proteins and accumulated as inclusion bodies. Western blotting demonstrated that the fusion protein could be recognized by the anti-PrP monoclonal antibody and used as antigen for preparing the monoclonal antibody against PrP.",
        "keywords": [
            "clone",
            "prion protein gene",
            "prokaryotic expression",
            "human"
        ],
        "authors": [
            {
                "name": "JIANG Hai-xia",
                "org": " College of Veterinary Medicine,Gansu Agricultural University,Lanzhou  Key Laboratory of Animal Virology,Ministry of Agriculture State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "LIU Yong-sheng",
                "org": " College of Veterinary Medicine,Gansu Agricultural University,Lanzhou  Key Laboratory of Animal Virology,Ministry of Agriculture State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "YANG Xiao-pu",
                "org": " College of Veterinary Medicine,Gansu Agricultural University,Lanzhou  Key Laboratory of Animal Virology,Ministry of Agriculture State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "CHEN Hao-tai",
                "org": " College of Veterinary Medicine,Gansu Agricultural University,Lanzhou  Key Laboratory of Animal Virology,Ministry of Agriculture State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "ZHU Xiao-ling",
                "org": " College of Veterinary Medicine,Gansu Agricultural University,Lanzhou  Key Laboratory of Animal Virology,Ministry of Agriculture State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": " College of Veterinary Medicine,Gansu Agricultural University,Lanzhou  Key Laboratory of Animal Virology,Ministry of Agriculture State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "XIE Qing-ge",
                "org": " College of Veterinary Medicine,Gansu Agricultural University,Lanzhou  Key Laboratory of Animal Virology,Ministry of Agriculture State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            }
        ],
        "venue": "Journal of Gansu Agricultural University",
        "year": 2006
    },
    "zoSUhoWX": {
        "id": "zoSUhoWX",
        "title": "Expression of Human Mature Prion-like Protein Doppel in Escherichia coli",
        "abstract": "HomDpl,the encoding gene of human mature prion-like protein Dopple,was amplified by PCR with the plasmid HoPrnd-T including the ORF of the human Prnd gene as a template.Then HomDpl was inserted into the EcoRⅠ-XhoⅠsite of pGEX-6P-1 vector to generate recombinant expression plasmid pGEX-homDpl.The pGEX-homDpl plasmid was transformed into host strain E.coli BL21(DE3) through electroporation.1.0 mmol/L IPTG was used to induce the recombinant E.coli to express homDpl protein.SDS-PAGE analysis demonstrated that homDpl protein was overexpressed in E.coli.",
        "keywords": [
            "expression",
            "mature prion-like protein Dopple",
            "Escherichia coli",
            "human"
        ],
        "authors": [
            {
                "name": "LU Wei",
                "org": ""
            },
            {
                "name": "ZHANG Jie",
                "org": "Key Laboratory of Animal Virology,Ministry of Agriculture,State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou,Gansu,,China"
            },
            {
                "name": "LIU Yong-sheng",
                "org": "Key Laboratory of Animal Virology,Ministry of Agriculture,State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou,Gansu,,China"
            },
            {
                "name": "WEI Guang-sen",
                "org": "Key Laboratory of Animal Virology,Ministry of Agriculture,State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou,Gansu,,China"
            }
        ],
        "venue": "Progress in Veterinary Medicine",
        "year": 2006
    },
    "HtMhILXp": {
        "id": "HtMhILXp",
        "title": "Cloning and analysis of prion protein genes from three mammals",
        "abstract": "Prion protein(PrP) genes of Qinchuan cattle,native born sheep of Gansu Province and Han nationality human being were amplified by PCR with the genome DNAs extracted from blood as templates,respectively,and analyzed with molecular biological softwares.The mammalian Prnp genes existed in a single extron and shared 99.0% homologies with the corresponding genes reported in GenBank.The homology in nucleotide sequence between bovine and ovine Prnp genes was 97.3%,and the similarity in deduced amino acids was 96.5%.The human Prnp gene shared 86.7% sequence identity with that of the cattle and shared 87.1% homology with the ovine Prnp gene.The deduced amino acids from Prnp genes shared 90.0% homologies between human and cattle or sheep.All the three Prnp genes had G-C-rich(element.) The PrP protein encoded by the Prnp genes comprised N-terminal signal,mature protein and C-terminal region attached by GPⅠ anchor.Genotype analysis showed that Qinchuan cattle and native born sheep probably had risk to be affected by spongiform encephalopathy.",
        "keywords": [
            "spongiform encephalopathy",
            "Prnp gene",
            "human being",
            "cellular prion protein(PrP~(c))",
            "sheep",
            "Qinchuan cattle",
            "scrapie prion protein(PrP~(sc))"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Key Laboratory of Animal Virology,Ministry of Agriculture/State Key Laboratory of Veterinary Etiological Biology/Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "LIU Yong-sheng",
                "org": "Key Laboratory of Animal Virology,Ministry of Agriculture/State Key Laboratory of Veterinary Etiological Biology/Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "CHEN Hao-tai",
                "org": "Key Laboratory of Animal Virology,Ministry of Agriculture/State Key Laboratory of Veterinary Etiological Biology/Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "JIANG Hai-xia",
                "org": "Key Laboratory of Animal Virology,Ministry of Agriculture/State Key Laboratory of Veterinary Etiological Biology/Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China;College of Veterinary Medicine,Gansu Agricultural University,Lanzhou ,China"
            },
            {
                "name": "LU Wei",
                "org": "College of Animal Science and Veterinary Medicine/Shenyang Agricultural University,Shenyang ,China"
            },
            {
                "name": "ZHU Xiao-ling",
                "org": "Key Laboratory of Animal Virology,Ministry of Agriculture/State Key Laboratory of Veterinary Etiological Biology/Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China;College of Veterinary Medicine,Gansu Agricultural University,Lanzhou ,China"
            },
            {
                "name": "XIE Qing-ge",
                "org": "Key Laboratory of Animal Virology,Ministry of Agriculture/State Key Laboratory of Veterinary Etiological Biology/Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            }
        ],
        "venue": "Veterinary Science in China",
        "year": 2006
    },
    "RgaImvH3": {
        "id": "RgaImvH3",
        "title": "Prokaryotic expression and bioactivity analysis of the Listeria monocytogenes listeriolysin O",
        "abstract": "The hlyA of Listeria monocytogenes was amplified by PCR and ligated with pMD18-T vector.The recombinant plasmid obtained was certified by PCR,restriction endonucleases analysis and sequencing.A prokaryotic expression plasmid, named pGEX-hlyA was constructed subsequently.After induced by IPTG,the expression product was tested by SDS-PAGE and Western blot.The result showed that 82 Ku fusion protein was recognized by positive serum against Listeria monocytogenes,and the protein could lyse swine red cell.The above results suggest that the Listeria monocytogenes hlyA was successfully expressed in E.coli,providing a solid foundation to develop indirect ELISA for diagnosis of this disease.",
        "keywords": [
            "expression",
            "Listeria monocytogenes hlyA",
            "bioactivity analysis"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Key Laboratory of Veterinary Parasitology of Gansu Province,State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute of Chinese Academy of Agricaltural Sciences,Lanzhou ,China;Energy Research Institute of Shandong Academy of Sciences,Ji'nan ,China"
            },
            {
                "name": "LUO Xue-nong",
                "org": "Key Laboratory of Veterinary Parasitology of Gansu Province,State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute of Chinese Academy of Agricaltural Sciences,Lanzhou ,China"
            },
            {
                "name": "ZHENG Ya-dong",
                "org": "Key Laboratory of Veterinary Parasitology of Gansu Province,State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute of Chinese Academy of Agricaltural Sciences,Lanzhou ,China"
            },
            {
                "name": "LI Hui",
                "org": "Key Laboratory of Veterinary Parasitology of Gansu Province,State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute of Chinese Academy of Agricaltural Sciences,Lanzhou ,China"
            },
            {
                "name": "FU Xiao-ping",
                "org": "College of Veterinary Medicine,Gansu Agricultural University,Lanzhou ,China"
            },
            {
                "name": "ZHU Xiao-ling",
                "org": "College of Veterinary Medicine,Gansu Agricultural University,Lanzhou ,China;Animal Sciences and Veterinary Medicine Institute of Shandong Academy of Agricultureal Sciences,Ji'nan ,China"
            }
        ],
        "venue": "Chinese Journal of Preventive Veterinary Medicine",
        "year": 2007
    },
    "e2ymDusn": {
        "id": "e2ymDusn",
        "title": "Isolation and identification of Listeria monocytogenes in sheep",
        "abstract": "Listeria monocytogenes(LM),as the important member of the genus Listeria,is a zoonotic and food-borne pathogen,and the disease is of significance in public health.In this study,the pathogen separated from sheep brain issues possibly infected by LM was primarily identified using biochemical and virulence and other conventional indentification methods.Parts of conserved nucleotide fragments of hlyA gene was amplified by PCR,and in view of the complete homology in nucleotide sequence of the hlyA gene in this study and that previously reported in the GenBank,the pathogen was finally determined as LM.The study provided an important reference method for specifically diagnosing and detecting LM.",
        "keywords": [
            "Listeria monocytogenes",
            "PCR identification",
            "sheep"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "College of Veterinary Medicine,Gansu Agricultural University,Lanzhou ,China;Key Laboratory of Veterinary Parasitology of Gansu Province,State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,CAAS,Lanzhou ,China;Energy Research Institute of Shandong Academy of Sciences,Jinan ,China"
            },
            {
                "name": "LI Hui",
                "org": "Key Laboratory of Veterinary Parasitology of Gansu Province,State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,CAAS,Lanzhou ,China"
            },
            {
                "name": "SUN Xiao-lin",
                "org": "College of Veterinary Medicine,Gansu Agricultural University,Lanzhou ,China;Key Laboratory of Veterinary Parasitology of Gansu Province,State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,CAAS,Lanzhou ,China"
            },
            {
                "name": "LUO Xue-nong",
                "org": "Key Laboratory of Veterinary Parasitology of Gansu Province,State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,CAAS,Lanzhou ,China"
            },
            {
                "name": "ZHENG Ya-dong",
                "org": "Key Laboratory of Veterinary Parasitology of Gansu Province,State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,CAAS,Lanzhou ,China"
            },
            {
                "name": "FU Xiao-ping",
                "org": "College of Veterinary Medicine,Gansu Agricultural University,Lanzhou ,China"
            }
        ],
        "venue": "Journal of Gansu Agricultural University",
        "year": 2007
    },
    "UeyjyjNv": {
        "id": "UeyjyjNv",
        "title": "Cloning and expression of bovine prion protein 27-30 gene",
        "abstract": "A 420 bp PrP~(27-30) gene fragment of the bovine Prop gene was amplified by PCR from plasmid BoPrnp-T containing the ORF of bovine Prnp gene.The PCR product was cloned into pPIC9K vector to produce recombinant plasmid pPIC9K-boPrP~(27-30) and transformed into E.coli JM109.The pPIC9K-boPrP~(27-30) was linearized with SalⅠand then transfected into Pichia Pastoris GS115 by electroporation.A recombinant strain GS115/pPIC9K-boPrP~(27-30) was obtained by G418 selection.Expression of the recombinant PrP was induced with 1.0% methanol and the expression products were identified by SDS-PAGE and Western blot analysis.The results demonstrated that bovine PrP~(27-30) gene was successfully expressed in Pichia Pastoris as a 27 Ku protein that could be specifically recognized by monoclonal antibody SAF-70.",
        "keywords": [
            "expression",
            "bovine PrP27~(27-30) gene",
            "cloning"
        ],
        "authors": [
            {
                "name": "LU Wei",
                "org": "Key Laboratory of Animal Virology,Ministry of Agriculture,State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China;Shenyang Agricultural University,Shenyang ,China"
            },
            {
                "name": "ZHANG Peng",
                "org": "Center for Animal Disease Control and Prevention of Liaoning Province,Shenyang ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Key Laboratory of Animal Virology,Ministry of Agriculture,State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "LIU Yong-sheng",
                "org": "Key Laboratory of Animal Virology,Ministry of Agriculture,State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "WEI Guang-sen",
                "org": "Key Laboratory of Animal Virology,Ministry of Agriculture,State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "CHEN Hao-tai",
                "org": "Key Laboratory of Animal Virology,Ministry of Agriculture,State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "JIANG Hai-xia",
                "org": "Gansu Agricutural University,Lanzhou ,China"
            },
            {
                "name": "ZHU Xiao-ling",
                "org": "Gansu Agricutural University,Lanzhou ,China"
            }
        ],
        "venue": "Chinese Journal of Preventive Veterinary Medicine",
        "year": 2007
    },
    "iB8eY7On": {
        "id": "iB8eY7On",
        "title": "Progress in conformation and property of prion proteins",
        "abstract": "Prion proteins including the cellular isoform of prion protein(PrPc) and the scrapie isoform of prion protein(PrPsc) were reviewed in the aspects of conformational characteristics,and properties of prion and its mutants.PrPsc was changed to PrPc through conformational change.PrP three-dimensional structures from different species have a similar globular domain from the 125 to 228 residues and a N-terminal flexibly disordered \"tail\".The globular domain contains three alpha-helices comprising the residues 144-154,173-194,200-228 and a short anti-parallel beta-sheet comprising the residues 128-131 and 161-164,but they were different in the structure and surface charge distribution.",
        "keywords": [
            "prion protein",
            "property",
            "conformation"
        ],
        "authors": [
            {
                "name": "CHEN Hao-tai",
                "org": "State Key Laboratory of Veterinary Etiological Biology/Key Laboratory of Animal Virology of the Ministry of Agriculture/Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "LIU Yong-sheng",
                "org": "State Key Laboratory of Veterinary Etiological Biology/Key Laboratory of Animal Virology of the Ministry of Agriculture/Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "State Key Laboratory of Veterinary Etiological Biology/Key Laboratory of Animal Virology of the Ministry of Agriculture/Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "WU Run",
                "org": "College of Veterinary Medicine,Gansu Agricultural University,Lanzhou ,China"
            },
            {
                "name": "LIU Xiang-tao",
                "org": "State Key Laboratory of Veterinary Etiological Biology/Key Laboratory of Animal Virology of the Ministry of Agriculture/Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            }
        ],
        "venue": "Veterinary Science in China",
        "year": 2007
    },
    "w4dpF72E": {
        "id": "w4dpF72E",
        "title": "Cloning and analysis of bovine,ovine and human dopple genes",
        "abstract": "The mammalian dopple gene Prnds from Qinchuan cattle,sheep native to Gansu province and The Han people were amplified by PCR,sequenced and analyzed with molecular biological softwares.The results showed that the mammalian Prnds existed in a single extron and shared high homologies with the corresponding genes deposited in GenBank.The nucleotide homology between bovine and ovine Prnd was 96.8 % and the similarity in deduced amino acids was 93.3 %.The human Prnd shared 80 % sequence identity with the bovine and ovine Prnd and its deduced amino acids shared 76.3 % homology with that of cattle and sheep.The primary structure analysis showed that dopple protein comprised a N-terminal signal,mature protein and C-terminal region attached by a GPI anchor.The secondary structure prediction showed that dopple protein had three α-helices and two β-strands.This study provided valuable information of mammalian dopple genes in China,and laid foundation for further studies on the gene structure and function.",
        "keywords": [
            "transmissible spongiform encephalopathy(TSE)",
            "dopple gene(Prnd)",
            "prion protein(PrP)",
            "Prion protein gene(Prnp)",
            "dopple(Dpl)"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "State Key Laboratory on Veterinary Etiology,Key Laborotary of Animal Virology of Ministry of Agriculture,Lanzhou Veterinary Research Institute of Chinese Academy Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "ZHANG Peng",
                "org": "Center for Animal Disease Control and Prevention of Liaoning Province,Shenyang ,China"
            },
            {
                "name": "LIU Yong-sheng",
                "org": "State Key Laboratory on Veterinary Etiology,Key Laborotary of Animal Virology of Ministry of Agriculture,Lanzhou Veterinary Research Institute of Chinese Academy Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "CHEN Hao-tai",
                "org": "State Key Laboratory on Veterinary Etiology,Key Laborotary of Animal Virology of Ministry of Agriculture,Lanzhou Veterinary Research Institute of Chinese Academy Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "JIANG Hai-xia",
                "org": "State Key Laboratory on Veterinary Etiology,Key Laborotary of Animal Virology of Ministry of Agriculture,Lanzhou Veterinary Research Institute of Chinese Academy Agricultural Sciences,Lanzhou ,China;College of Veterinary Medicine,Gansu Agricultural University,Lanzhou ,China"
            },
            {
                "name": "LU Wei",
                "org": "Shenyang Agricultural University,Shenyang ,China"
            },
            {
                "name": "ZHU Xiao-ling",
                "org": "State Key Laboratory on Veterinary Etiology,Key Laborotary of Animal Virology of Ministry of Agriculture,Lanzhou Veterinary Research Institute of Chinese Academy Agricultural Sciences,Lanzhou ,China;Shenyang Agricultural University,Shenyang ,China"
            },
            {
                "name": "XIE Qing-ge",
                "org": "State Key Laboratory on Veterinary Etiology,Key Laborotary of Animal Virology of Ministry of Agriculture,Lanzhou Veterinary Research Institute of Chinese Academy Agricultural Sciences,Lanzhou ,China"
            }
        ],
        "venue": "Chinese Journal of Preventive Veterinary Medicine",
        "year": 2007
    },
    "WokWf5jm": {
        "id": "WokWf5jm",
        "title": "Dissection on Genetic Diversiy of Foot-and-Mouth Disease Virus Genomes",
        "abstract": "【Objective】The purpose of this study is to clarify the structural features of foot-and-mouth disease virus (FMDV) genomes, relationships of the sequence variations with its structure-function, and molecular phylogeny among FMDV. 【Method】 The identity analysis and multiple alignment of 184 FMDV genome sequences were undertaken, respectively, by using the DNAstar and Clustalx packages. 【Result】 FMDV genome sequences showed the entire ORFs size range from 6 963 to 7 120 nt, which could encode PrPs with 2 320 to 2 339 aa. The homology of these nucleotide and amino acid sequences were greater than or equal to 77.6% and greater than or equal to 78.3% among seven distinct serotypes, respectively. The data reveal novel highly conserved genomic regions, indicating variability as well as novel viral genomic motifs with likely biological relevance. 【Conclusion】 These results suggest that more FMDV genome diversity may exist in nature than is currently indicated by serology or sequence analysis.",
        "keywords": [
            "Genetic diversity",
            "FMDV"
        ],
        "authors": [
            {
                "name": "CHEN Hao-tai",
                "org": "Key Laboratory of Animal Virology of Ministry of Agriculture/State Key Laboratory of Veterinary Etiological Biology/Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences/Key Laboratory of Grazing Animal Diseases of Ministry of Agriculture, Lanzhou "
            },
            {
                "name": "ZHANG Jie",
                "org": "Key Laboratory of Animal Virology of Ministry of Agriculture/State Key Laboratory of Veterinary Etiological Biology/Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences/Key Laboratory of Grazing Animal Diseases of Ministry of Agriculture, Lanzhou "
            },
            {
                "name": "SUN De-hui",
                "org": "Key Laboratory of Animal Virology of Ministry of Agriculture/State Key Laboratory of Veterinary Etiological Biology/Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences/Key Laboratory of Grazing Animal Diseases of Ministry of Agriculture, Lanzhou "
            },
            {
                "name": "MA Li-na",
                "org": "Key Laboratory of Animal Virology of Ministry of Agriculture/State Key Laboratory of Veterinary Etiological Biology/Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences/Key Laboratory of Grazing Animal Diseases of Ministry of Agriculture, Lanzhou "
            },
            {
                "name": "LIU Xiang-tao",
                "org": "Key Laboratory of Animal Virology of Ministry of Agriculture/State Key Laboratory of Veterinary Etiological Biology/Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences/Key Laboratory of Grazing Animal Diseases of Ministry of Agriculture, Lanzhou "
            },
            {
                "name": "LIU Yong-sheng",
                "org": "Key Laboratory of Animal Virology of Ministry of Agriculture/State Key Laboratory of Veterinary Etiological Biology/Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences/Key Laboratory of Grazing Animal Diseases of Ministry of Agriculture, Lanzhou "
            }
        ],
        "venue": "Scientia Agricultura Sinica",
        "year": 2008
    },
    "fSW7NeWT": {
        "id": "fSW7NeWT",
        "title": "Expression of doppel(Dpl) gene in human,cattle and sheep and preparation of bovine Dpl antisera",
        "abstract": "The prion-like protein doppel(Dpl) is closely related with the function of prion.An experiment was carried out to prepare the Dpl antisera for specific detection of the recombinant Dpl and the Dpl from animal tissues.The Dpl antisera would be uesed to study DPl function and its relationship with PrP.According to the sequence analysis of cloned Dpl gene in human,cattle and sheep,their mature Dpl encoding region were cloned into pET-30a(+) and those recombinant expression vectors were constructed,respectively.The recombinant plasmids were transformed into E.coli BL21(DE3)pLysS and IPTG was used to induce the expression of recombinant Dpl.The four Chinchilla rabbits were immunized with the purified bovine fused Dpl and antisera was prepared.SDS-PAGE analysis indicated that three different fused protein were overexpressed in E.coli.The fused protein was purified with Ni-NTA resin and gel-elution.ELISA and West-blot analysis indicated the rabbit antisera against bovine Dpl could react specificly with fused Dpl of human,cattle and sheep,and natural Dpl in testicle tissue of cattle and sheep.Dpl antisera could not react with fused PrP of human,cattle and sheep.These results indicated that the cattle Dpl antisera could be used to detect and study on the Dpl in human,cattle and sheep.",
        "keywords": [
            "transmissible spongiform encephalopathy(TSE)",
            "antisera",
            "gene expression",
            "prion protein(PrP)",
            "doppel(Dpl)"
        ],
        "authors": [
            {
                "name": "LIU Yong-sheng",
                "org": "Key Laboratory of Animal Virology of Ministry of Agriculture/State Key Laboratory of Veterinary Etiological Biology/Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "TANG Jiang-shan",
                "org": "Key Laboratory of Animal Virology of Ministry of Agriculture/State Key Laboratory of Veterinary Etiological Biology/Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "LU Wei",
                "org": "Key Laboratory of Animal Virology of Ministry of Agriculture/State Key Laboratory of Veterinary Etiological Biology/Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "CHEN Hao-tai",
                "org": "Key Laboratory of Animal Virology of Ministry of Agriculture/State Key Laboratory of Veterinary Etiological Biology/Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "SUN De-hui",
                "org": "Key Laboratory of Animal Virology of Ministry of Agriculture/State Key Laboratory of Veterinary Etiological Biology/Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "CAI Xue-peng",
                "org": "Key Laboratory of Animal Virology of Ministry of Agriculture/State Key Laboratory of Veterinary Etiological Biology/Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Key Laboratory of Animal Virology of Ministry of Agriculture/State Key Laboratory of Veterinary Etiological Biology/Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            }
        ],
        "venue": "Journal of China Agricultural University",
        "year": 2008
    },
    "6ooDnA4R": {
        "id": "6ooDnA4R",
        "title": "Isolation and Identification of Haemophilus paragallinarum",
        "abstract": "Haemophilus paragallinarum(HPG) is causative agent of Infectious Coryza(IC).In recent years,it has been proved that the occurrence of the disease in Beijing,Shanxi,Sichuan and other regions.In order to understand the prevalence of conditions of the disease in Shandong Province,6 strains of bacteria were isolated from 20 suspected Infectious Coryza chickens in vivo from five farms in Dezhou region of Shandong Province,and identified as Haemophilus paragallinarum by the bacterial culturing,biochemical tests,sequencing of 16S rDNA gene,chicken embryo inoculation test.Slide agglutination test and Dot-ELISA,Hemagglutination test confirmed that bacteria isolated from six strains are A-type.Thus for the future of infectious coryza of",
        "keywords": [
            "chickem embrgo imoculation test",
            "haemophilus paragallinrum",
            "isolation and identification",
            "drug sensitive test",
            "haemophilus parasuis",
            "serotyping",
            "16s rrna",
            "epidemiology",
            "disease prevalence"
        ],
        "authors": [
            {
                "name": "MA Yan-ping",
                "org": "State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Gansu Lanzhou ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Gansu Lanzhou ,China"
            },
            {
                "name": "CHEN Hao-tai",
                "org": "State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Gansu Lanzhou ,China"
            },
            {
                "name": "MA Li-na",
                "org": "State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Gansu Lanzhou ,China"
            },
            {
                "name": "DING Yao-zhong",
                "org": "State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Gansu Lanzhou ,China"
            },
            {
                "name": "YANG Sheng-hai",
                "org": "State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Gansu Lanzhou ,China"
            },
            {
                "name": "LIU Yong-sheng",
                "org": "State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Gansu Lanzhou ,China"
            }
        ],
        "venue": "Southwest China Journal of Agricultural Sciences",
        "year": 2009
    },
    "cCJvkday": {
        "id": "cCJvkday",
        "title": "Influence of Pathogenic Microorganisms in Sewage on Public Health Security and Their Control Strategy",
        "abstract": "From the point of view of pathogenic microorganisms,the article summarized the research progress in the influence of pathogenic microorganisms in sewage on public health security in the world,including the examination method of pathogenic microorganisms,the factors influential to the prevailing and distribution of the pathogens,improvement of quality evaluation indexes of sewage treatment.",
        "keywords": [
            "Zoonosis",
            "Water environment",
            "Pathogenic microorganism",
            "Biology safety"
        ],
        "authors": [
            {
                "name": "LIU Yong-sheng",
                "org": "State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            }
        ],
        "venue": "Acta Agriculturae Jiangxi",
        "year": 2009
    },
    "bzfJcP7p": {
        "id": "bzfJcP7p",
        "title": "Cloning and Construction of Eukaryotic Expression Vector of HN Gene of Newcastle Disease Virus Roakin Strain",
        "abstract": "To clone The HN gene of Newcastle disease virus(NDV) Roakin strain and construct a eukaryotic expression vector which can be expressed in Chinese Hamster Ovary Cells CHO/dhfr-.The HN gene of Newcastle disease virus(NDV) Roakin strain was amplified by RT-PCR and cloned into pMD18-T vector and sequenced.The HN gene of the virus and dhfr gene was cloned into high efficient eukaryotic vector pCI-neo.PCR amplification,restriction emzyme digestion and sequencing analysis was applied to identify the recombinant expression plasmids.The sequence homology of HN cloned with the HN(AY289000)on GenBank was 99.8%;Mammalian recombinant expression plasmid pCI-HN-D was constructed.Recombinant expression plasmid pCI-HN-D harboring dhfr gene and HN gene of NDV has been successfully constructed and lay the foundation of high-level expression of HN protein of NDV in mammalian cell CHO/dhfr-.",
        "keywords": [
            "dhfr gene",
            "Eukaryotic expression vector",
            "HN gene",
            "NDV"
        ],
        "authors": [
            {
                "name": "ZHANG Jile",
                "org": "College of Veterinary Medicine,Northwest A&F University,Yangling Shaanxi ,China;Key Laboratory of Animal Virology of,Ministry of Agriculture/ State Key Laboratory of Veterinary Etiological Biology/ Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou Gansu ,China"
            },
            {
                "name": "CHEN Haotai",
                "org": "Key Laboratory of Animal Virology of,Ministry of Agriculture/ State Key Laboratory of Veterinary Etiological Biology/ Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou Gansu ,China"
            },
            {
                "name": "DING Yaozhong",
                "org": "Key Laboratory of Animal Virology of,Ministry of Agriculture/ State Key Laboratory of Veterinary Etiological Biology/ Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou Gansu ,China"
            },
            {
                "name": "SUN Dehui",
                "org": "Key Laboratory of Animal Virology of,Ministry of Agriculture/ State Key Laboratory of Veterinary Etiological Biology/ Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou Gansu ,China"
            },
            {
                "name": "MA Lina",
                "org": "Key Laboratory of Animal Virology of,Ministry of Agriculture/ State Key Laboratory of Veterinary Etiological Biology/ Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou Gansu ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Key Laboratory of Animal Virology of,Ministry of Agriculture/ State Key Laboratory of Veterinary Etiological Biology/ Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou Gansu ,China"
            },
            {
                "name": "JIN Lei",
                "org": "Key Laboratory of Animal Virology of,Ministry of Agriculture/ State Key Laboratory of Veterinary Etiological Biology/ Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou Gansu ,China"
            },
            {
                "name": "GAO Yunying",
                "org": "College of Veterinary Medicine,Northwest A&F University,Yangling Shaanxi ,China"
            },
            {
                "name": "LIU Yongsheng",
                "org": "Key Laboratory of Animal Virology of,Ministry of Agriculture/ State Key Laboratory of Veterinary Etiological Biology/ Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou Gansu ,China"
            }
        ],
        "venue": "Acta Agriculturae Boreali-Occidentalis Sinica",
        "year": 2009
    },
    "zyDye5Qg": {
        "id": "zyDye5Qg",
        "title": "Research Progress in Streptococcus suis and Its Inspection Technology",
        "abstract": "Streptococcus suis is the zoonosis which is caused by the Gram-positive facultative anaerobic cocci.The author summarized the research advance in the infectious factors and inspection technology of Streptococcus suis.",
        "keywords": [
            "Inspection technology",
            "Streptococcus suis",
            "Gene chip"
        ],
        "authors": [
            {
                "name": "DING Xiao-long",
                "org": "Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Key Laboratory of Animal Virology of Ministry of Agriculture,State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China;China Agricultural Vet Biology Science and Technology Co.Ltd.,Lanzhou ,China"
            },
            {
                "name": "DING Yao-zhong",
                "org": "Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Key Laboratory of Animal Virology of Ministry of Agriculture,State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "CHENG Fang-zhen",
                "org": "China Agricultural Vet Biology Science and Technology Co.Ltd.,Lanzhou ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Key Laboratory of Animal Virology of Ministry of Agriculture,State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            }
        ],
        "venue": "Acta Agriculturae Jiangxi",
        "year": 2009
    },
    "qy7Myhw1": {
        "id": "qy7Myhw1",
        "title": "Development of Synthetical Peptide Vaccine of Foot and Mouth Disease",
        "abstract": "The research and development of synthetic peptide vaccine of FMD was reviewed in this paper.Vaccination is an effective measure of prevention for foot and mouth disease(FMD).With development of molecular biology and immunology,new type vaccines of FMD would be developed.",
        "keywords": [
            "synthetical peptide vaccine",
            "FMD"
        ],
        "authors": [
            {
                "name": "Ma Lina",
                "org": "Key Laboratory of Grazing Animal Diseases of Ministry of Agriculture,Key Laboratory of Animal Virology of Ministry of Agriculture,State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou "
            },
            {
                "name": "Liu Yongsheng",
                "org": "Key Laboratory of Grazing Animal Diseases of Ministry of Agriculture,Key Laboratory of Animal Virology of Ministry of Agriculture,State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou "
            },
            {
                "name": "Chen Haotai",
                "org": "Key Laboratory of Grazing Animal Diseases of Ministry of Agriculture,Key Laboratory of Animal Virology of Ministry of Agriculture,State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou "
            },
            {
                "name": "Zhang Jie",
                "org": "Key Laboratory of Grazing Animal Diseases of Ministry of Agriculture,Key Laboratory of Animal Virology of Ministry of Agriculture,State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou "
            }
        ],
        "venue": "Chinese Agricultural Science Bulletin",
        "year": 2009
    },
    "59icYyne": {
        "id": "59icYyne",
        "title": "Foot and Mouth Diseases (FMD) and Advances in Inspection Technology in FMD",
        "abstract": "Foot-and-mouth diseases(FMD) including seven main blood serums, which has listed one of the most important infectious disease by OIE and our Government. Recent years, it frequently breaks out, and seriously threat Animal Production and human -self security, because it has many subtype, strong antigenic variation microorganism and wide host range. FMD's ecological and common healthy meaning already acquired mankinds highly concern, The Paper has summarized the infection mechanism and some diagnosis and control measures of FMD.",
        "keywords": [
            "gene chip",
            "Foot and mouth diseases (FMD)",
            "inspection technology",
            "biosensor"
        ],
        "authors": [
            {
                "name": "Ding Yaozhong",
                "org": "Key Laboratory of Veterinary Public Health of Ministry of Agriculture, Key Laboratory of Animal Virology of Ministry of Agriculture, State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou "
            },
            {
                "name": "Zhang Jie",
                "org": "Key Laboratory of Veterinary Public Health of Ministry of Agriculture, Key Laboratory of Animal Virology of Ministry of Agriculture, State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou "
            },
            {
                "name": "Chen Haotai",
                "org": "Key Laboratory of Veterinary Public Health of Ministry of Agriculture, Key Laboratory of Animal Virology of Ministry of Agriculture, State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou "
            },
            {
                "name": "Ma Yanping",
                "org": "Key Laboratory of Veterinary Public Health of Ministry of Agriculture, Key Laboratory of Animal Virology of Ministry of Agriculture, State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou "
            },
            {
                "name": "Liu Yongsheng",
                "org": "Key Laboratory of Veterinary Public Health of Ministry of Agriculture, Key Laboratory of Animal Virology of Ministry of Agriculture, State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou "
            }
        ],
        "venue": "Chinese Agricultural Science Bulletin",
        "year": 2009
    },
    "AswYwN30": {
        "id": "AswYwN30",
        "title": "Research Progress on Detection of Porcine Reproductive and Respiratory Syndrome",
        "abstract": "Porcine reproductive and respiratory syndrome(PRRS) is viral pestilence,obstacling to breeding sows and piglets serious respiratory symptoms and high mortality.Its incidence and prevalence of the pig farming industry cause enormous economic losses,it has become more serious viral disease.Timely and accurate detection of the disease in order to take corresponding measures are the key to the success of disease control.This article reviews the serum study,etiology,molecular biology,etc.to clarify the porcine reproductive and respiratory syndrome detection technology,in order to veterinary clinical diagnosis and treatment.",
        "keywords": [
            "serum study",
            "porcine reproductive and respiratory syndrome",
            "etiology",
            "molecular biology"
        ],
        "authors": [
            {
                "name": "Ma Yanping",
                "org": "State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,Key Laboratory of Veterinary Public Health of Ministry of Agriculture, Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou "
            },
            {
                "name": "Zhang Jie",
                "org": "State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,Key Laboratory of Veterinary Public Health of Ministry of Agriculture, Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou "
            },
            {
                "name": "Chen Haotai",
                "org": "State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,Key Laboratory of Veterinary Public Health of Ministry of Agriculture, Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou "
            },
            {
                "name": "Ding Yaozhong",
                "org": "State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,Key Laboratory of Veterinary Public Health of Ministry of Agriculture, Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou "
            },
            {
                "name": "Liu Yongsheng",
                "org": "State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,Key Laboratory of Veterinary Public Health of Ministry of Agriculture, Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou "
            }
        ],
        "venue": "Chinese Agricultural Science Bulletin",
        "year": 2009
    },
    "7ZLejmKJ": {
        "id": "7ZLejmKJ",
        "title": "Study on metabolic pathway of L-lactic acid fermentation from xylose by microorganism",
        "abstract": "Xylose is widespread in forest and agricultural residues.Xylose can be fermented to L-lactic acid which is an effective exploitation of renewable materials.In this paper,different xylose metabolic pathways of various microorganisms were summarized,based on which the key enzymes and their functions were analyzed.Finally,application and progress of metabolic engineering in fermenting L-lactic acid from xylose were briefly introduced.",
        "keywords": [
            "L-lactic acid",
            "xylose",
            "metabolic engineering"
        ],
        "authors": [
            {
                "name": "FU Xiao-fen",
                "org": "Institute of Agri-Food Science and Technology,Chinese Academy of Agricultural Sciences,Beijing ,China"
            },
            {
                "name": "JIANG Jun-ping",
                "org": "Institute of Agri-Food Science and Technology,Chinese Academy of Agricultural Sciences,Beijing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Institute of Agri-Food Science and Technology,Chinese Academy of Agricultural Sciences,Beijing ,China"
            },
            {
                "name": "GONG Xiao",
                "org": "College of Food Science,Southwest University,Chongqing ,China"
            }
        ],
        "venue": "Science and Technology of Food Industry",
        "year": 2009
    },
    "RQP5vytl": {
        "id": "RQP5vytl",
        "title": "Research Progress on Detection of Haemophilus parasuis",
        "abstract": "Haemophilus parasuis is the causative agent of polyserositis in pigs, a mostly fatal disease on upper respiratory tract of pigs. It is also the pathogen of Glssers,diseases. In recent years, it has become one of severe bacterial diseases which endanger the raise of pigs. Detection of the disease exactly and timely is the key to prevent the disease successfully. This article summarizes the research progresses of Haemophilus parasuis in aspects of serology, etiology and molecular biology, so as to provide some reference for the clinical practice of veterinary medicine.",
        "keywords": [
            "Molecular biology",
            "Etiology",
            "Detection",
            "Haemophilus parasuis",
            "Serology"
        ],
        "authors": [
            {
                "name": "MA Yan-ping",
                "org": "State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Animal Virology of Ministry of Agriculture, Key Laboratory of Veterinary Public Health of Ministry of Agriculture, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou , Gansu, China"
            },
            {
                "name": "LIU Yong-sheng",
                "org": "State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Animal Virology of Ministry of Agriculture, Key Laboratory of Veterinary Public Health of Ministry of Agriculture, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou , Gansu, China"
            },
            {
                "name": "ZHANG Jie",
                "org": "State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Animal Virology of Ministry of Agriculture, Key Laboratory of Veterinary Public Health of Ministry of Agriculture, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou , Gansu, China"
            }
        ],
        "venue": "Progress in Modern Biomedicine",
        "year": 2009
    },
    "If57Wxtx": {
        "id": "If57Wxtx",
        "title": "Research and application of biosensor in public health surveillance",
        "abstract": "The sensors have rapid development as one kind of higher technology and newer technology the examination method and attracted the extensive interest of Chinese and foreign scholars,and becomed the key researched and the developedmed new technology,many scholars have interested that the multi-domain development's potential and the prospect of biosensor.The method had advantages of Sensitive,convenient,simple,rapid and the economical practical characteristic,and used in industry,agriculture,environmental monitoring and biomedicine. This article abstracted the research and application of sensors development in public health monitor forecasted.",
        "keywords": [
            "Biosensor",
            "Public health surveillance",
            "Research and application"
        ],
        "authors": [
            {
                "name": "Ding Yaozhong",
                "org": "2. lanzhou jiaotong university bowen college, lanzhuoo "
            },
            {
                "name": "Zhang Jie",
                "org": "2. lanzhou jiaotong university bowen college, lanzhuoo "
            },
            {
                "name": "Wei Gang",
                "org": "2. lanzhou jiaotong university bowen college, lanzhuoo "
            },
            {
                "name": "Liu Yongsheng",
                "org": "2. lanzhou jiaotong university bowen college, lanzhuoo "
            }
        ],
        "venue": "Modern Instruments",
        "year": 2009
    },
    "oGeUQ36j": {
        "id": "oGeUQ36j",
        "title": "Research Advances in Application of RNA Interference Technique",
        "abstract": "RNA interference(RNAi) refers to high-efficient and specific degradation phenomenon of homologous mRNA induced by double-stranded RNA in the highly conserved evolutionary course.RNAi technology has rapidly developed in the biomedicine research,it has played an important role in identifying unknown genes,tumour,antiviral infection and so on.This thesis sums up the action mechanism of RNAi,the carrier,the application situation and the prospects in mammal.",
        "keywords": [
            "Mechanism",
            "Mediated vector",
            "Gene silence",
            "Application",
            "RNAi"
        ],
        "authors": [
            {
                "name": "WANG Meng",
                "org": "State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "MA Yan-ping",
                "org": "State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "CHEN Hao-tai",
                "org": "State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "MA Li-na",
                "org": "State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "DING Yao-zhong",
                "org": "State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "YANG Sheng-hai",
                "org": "State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "LIU Yong-sheng",
                "org": "State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            }
        ],
        "venue": "Acta Agriculturae Jiangxi",
        "year": 2009
    },
    "zfjXLWKH": {
        "id": "zfjXLWKH",
        "title": "The Principles and Appliances of the Methods of Detecting the Protein Interactions in Heterogeneous System",
        "abstract": "The accomplishments of the genome sequencing do not explain the nature of life.Scientists are finding that all cell function involves protein interactions and some of disease is due to the change of protein interactions,so the study of protein interactions is of importance.At present,there are many practical and mature technologies for the detection of protein-protein interaction.The methods of detecting the protein interactions in heterogeneous system include Yeast two-hybrid system,Mammalian two-hybrid system,Bacterial two-hybrid system and Co-Immunoprecipitation.The principles and appliances of these methods are stated in this paper.",
        "keywords": [
            "methods",
            "protein",
            "heterogeneous system",
            "interaction"
        ],
        "authors": [
            {
                "name": "Ma Yanping",
                "org": "State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou "
            },
            {
                "name": "Liu Yongsheng",
                "org": "State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou "
            },
            {
                "name": "Zhang Jie",
                "org": "State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou "
            }
        ],
        "venue": "Chinese Agricultural Science Bulletin",
        "year": 2009
    },
    "gYeGkici": {
        "id": "gYeGkici",
        "title": "Research Progress in Genetic Engineering Vaccine of Foot-and-mouth Disease",
        "abstract": "The paper introduced the current status of outbreak of foot-and-mouth disease and the research and application of the vaccine of this disease in the world,and emphatically summarized the research progresses in various genetic engineering vaccines of foot-and-mouth disease.",
        "keywords": [
            "Molecular biology",
            "Genetic engineering vaccine",
            "Progress",
            "Foot-and-mouth disease"
        ],
        "authors": [
            {
                "name": "YANG Sheng-hai",
                "org": "Key Laboratory of Animal Virology,Ministry of Agriculture;China Agricultural Veterinarian Biological Science and Technology Co.Ltd.,Lanzhou ,China"
            },
            {
                "name": "YIN Hong",
                "org": "Key Laboratory of Animal Virology,Ministry of Agriculture"
            },
            {
                "name": "ZHANG Jie",
                "org": "Key Laboratory of Animal Virology,Ministry of Agriculture"
            },
            {
                "name": "LIU Yong-sheng",
                "org": "Key Laboratory of Animal Virology,Ministry of Agriculture"
            },
            {
                "name": "CHEN Hao-tai",
                "org": "Key Laboratory of Animal Virology,Ministry of Agriculture"
            },
            {
                "name": "MA Li-na",
                "org": "Key Laboratory of Animal Virology,Ministry of Agriculture"
            },
            {
                "name": "MA Yan-ping",
                "org": "Key Laboratory of Animal Virology,Ministry of Agriculture"
            },
            {
                "name": "DING Yao-zhong",
                "org": "Key Laboratory of Animal Virology,Ministry of Agriculture"
            }
        ],
        "venue": "Acta Agriculturae Jiangxi",
        "year": 2009
    },
    "szxhx8Lq": {
        "id": "szxhx8Lq",
        "title": "Research and Application of Riboswitches",
        "abstract": "Riboswitches are defined as a class of the mRNA components at mRNA3'-or the 5'-UTR which can be combined with small molecule metabolites to control gene transcription and translation.Riboswitches,which come from an RNA-based primitive world,are of catholic concern.This thesis sums up the mechanism of action and application of riboswitches.",
        "keywords": [
            "riboswitches",
            "small molecule metabolites",
            "regulate"
        ],
        "authors": [
            {
                "name": "Wang Meng",
                "org": "Key laboratory of Veterinary Public Health of Agriculture,Key Laboratory of Animal Virology of Ministry of Agriculture,State Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou "
            },
            {
                "name": "Ma Yanping",
                "org": "Key laboratory of Veterinary Public Health of Agriculture,Key Laboratory of Animal Virology of Ministry of Agriculture,State Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou "
            },
            {
                "name": "Liu Yongsheng",
                "org": "Key laboratory of Veterinary Public Health of Agriculture,Key Laboratory of Animal Virology of Ministry of Agriculture,State Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou "
            },
            {
                "name": "Zhang Jie",
                "org": "Key laboratory of Veterinary Public Health of Agriculture,Key Laboratory of Animal Virology of Ministry of Agriculture,State Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou "
            }
        ],
        "venue": "Chinese Agricultural Science Bulletin",
        "year": 2009
    },
    "iR0TXR7q": {
        "id": "iR0TXR7q",
        "title": "Research progress regarding function of cellular prion protein PrP~C and lipid raft protein flotillin",
        "abstract": "The prion protein and the lipid raft proteins are the current emphases.The normal cellular prion protein,PrP C,may lead to the occurrence of the spongiform encephalopathy by its transconformation PrP Sc,the scrapie prion protein.However,the mechanism of how PrP C convert to PrP Sc is unclear until now.PrP C is an important signal transduction protein,triggering a serial of signal transduction events.The flotillins belongs to the newly-named SPFH(stomatin/prohibitin/flotillin/HflK/C)protein family,and it is an important marker protein for lipid raft.Flotillins not only provides membrane platform for protein interaction acting as a scaffolding proteins,but also an important signaling protein participating numerous vital processes of the cell during assembly of the multiprotein complex and signal transduction.Flotillins can interact with PrP C and provide a platform for the transmembrane signal transduction of PrP C and the transconformation from PrP C to PrP Sc.This paper reviewed the research progress in recent 5 years regarding the function of PrP C and flotillins,especially the concern of the signal transduction.",
        "keywords": [
            "lipid raft protein",
            "spongiform encephalopathy",
            "flotillin/reggies",
            "signal transduction",
            "cellular prion protein(PrP C)"
        ],
        "authors": [
            {
                "name": "LIU Yong-sheng",
                "org": "Key Laboratory of Veterinary Public Health of Ministry of Agriculture/Key Laboratory of Animal Virology of Ministry of Agriculture/State Key Laboratory of Veterinary Etiological Biology/Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Key Laboratory of Veterinary Public Health of Ministry of Agriculture/Key Laboratory of Animal Virology of Ministry of Agriculture/State Key Laboratory of Veterinary Etiological Biology/Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "MA Li-na",
                "org": "Key Laboratory of Veterinary Public Health of Ministry of Agriculture/Key Laboratory of Animal Virology of Ministry of Agriculture/State Key Laboratory of Veterinary Etiological Biology/Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "CHEN Hao-tai",
                "org": "Key Laboratory of Veterinary Public Health of Ministry of Agriculture/Key Laboratory of Animal Virology of Ministry of Agriculture/State Key Laboratory of Veterinary Etiological Biology/Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            }
        ],
        "venue": "Journal of China Agricultural University",
        "year": 2009
    },
    "FWPVjfYT": {
        "id": "FWPVjfYT",
        "title": "Progress of Porcine circovirus Type 2(PCV2) and Its Diagnosis Technology",
        "abstract": "Porcine circovirus type 2(PCV2) belongs to family Circoviridae with 2 serotypes PCV1 and PCV2.The PCV1 widely exists in pig without pathogenicity,but the PCV2 could induce a series of pig synthetic diseases directly or indirectly,such as porcine reproductive and respiratory syndrome virus(PRRSV),postweaning multisystemic wasting syndrome(PMWS),porcine respiratory disease complex(PRDC),porcine dermatitis and nephropathy syndrome(PDNS).In order to understand pathogenic factors of PCV2 and set up a rapid identification and diagnosis technique,this paper summarizes studies of PCV2,its relative pathogenic factors and current diagnosis technology,which is expected to provide a reference for study on occurrence and diagnosis of PCV2.",
        "keywords": [
            "porcine dermatitis and nephropathy syndrome(pdns)",
            "porcine circovirus type 2(pcv2)",
            "postweaning multisystemic wasting syndrome(pmws)",
            "diagnosis technology",
            "diagnosis",
            "pathogenicity"
        ],
        "authors": [
            {
                "name": "DING Yao-zhong",
                "org": "Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences"
            },
            {
                "name": "LIU Yong-sheng",
                "org": "State Key Laboratory of Veterinary Etiological Biology"
            },
            {
                "name": "ZHANG Jie",
                "org": "Key Laboratory of Animal Virology of Ministry of Agriculture"
            }
        ],
        "venue": "Guizhou Agricultural Sciences",
        "year": 2009
    },
    "ISbuBPos": {
        "id": "ISbuBPos",
        "title": "Expression of HN gene of Newcastle disease virus in CHO/dhf cells",
        "abstract": "To stably express hemagglutinin-neuramidinase(HN) gene of Newcastle disease virus(NDV) in CHO/dhf cells,the HN and dhfr gene were cloned into high efficient eukaryotic vector pCI-neo,respectively.Then the recombinant plasmid was purified and transfected into CHO/dhf cells using Lipofectamine 2000,and the stable expressive cells were selected by methotrexate.The HN protein was detected by Western-blot and indirect immunofluorescence analysis.The results showed that the HN protein was expressed successfully.",
        "keywords": [
            "expression",
            "newcastle disease virus",
            "hn gene",
            "dhfr",
            "cho/dhf cell",
            "recombination",
            "genes",
            "plasmids",
            "sialidase",
            "gene expression",
            "recombinant proteins",
            "transfection",
            "dna cloning"
        ],
        "authors": [
            {
                "name": "ZHANG Ji-le",
                "org": "Key Laboratory of Animal Virology of the Ministry of Agriculture/State Key Laboratory of Veterinary Etiological Biology/Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "CHEN Hao-tai",
                "org": "Key Laboratory of Animal Virology of the Ministry of Agriculture/State Key Laboratory of Veterinary Etiological Biology/Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Key Laboratory of Animal Virology of the Ministry of Agriculture/State Key Laboratory of Veterinary Etiological Biology/Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "MA Li-na",
                "org": "Key Laboratory of Animal Virology of the Ministry of Agriculture/State Key Laboratory of Veterinary Etiological Biology/Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "JIN Lei",
                "org": "Key Laboratory of Animal Virology of the Ministry of Agriculture/State Key Laboratory of Veterinary Etiological Biology/Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "LIU Yong-sheng",
                "org": "Key Laboratory of Animal Virology of the Ministry of Agriculture/State Key Laboratory of Veterinary Etiological Biology/Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            }
        ],
        "venue": "Chinese Veterinary Science",
        "year": 2009
    },
    "77AeFdxp": {
        "id": "77AeFdxp",
        "title": "Research Progress in Immunity of Animal Alimentary Canal Mucosa",
        "abstract": "In this thesis,the composition of animal alimentary canal mucosa immune system is introduced,and the mechanism of the immunity of animal alimentary canal mucosa and the influential factors are expounded.",
        "keywords": [
            "Mucosa vaccine",
            "Mechanism of immunity",
            "Alimentary canal",
            "Immunity of mucosa"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "LIU Yong-sheng",
                "org": "State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            }
        ],
        "venue": "Acta Agriculturae Jiangxi",
        "year": 2009
    },
    "fRYti76X": {
        "id": "fRYti76X",
        "title": "Research Progress in Pathogenic Mechanism of Avian Influenza Virus",
        "abstract": "Avian Influenza Virus(AIV) belongs to Orthomyxoviridae,it can be classified into various subtypes on the basis of antigenic differences between the two surface glycoproteins: hemagglutinin and neuraminidase.As a consequence this virus has inflicted great economic damage to the poultry industry.This article sums up the research progress in the molecular structure and pathogenic mechanism of AIV.",
        "keywords": [
            "Molecular structure",
            "Avian influenza virus",
            "Pathogenic mechanism"
        ],
        "authors": [
            {
                "name": "YANG Sheng-hai",
                "org": "Key Laboratory of Animal Virology,Ministry of Agriculture,State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China;China Agricultural Veterinarian Biology Science and Technology Co.Ltd.,Lanzhou ,China"
            },
            {
                "name": "YIN Hong",
                "org": "Key Laboratory of Animal Virology,Ministry of Agriculture,State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "LIU Yong-sheng",
                "org": "Key Laboratory of Animal Virology,Ministry of Agriculture,State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "CHEN Hao-tai",
                "org": "Key Laboratory of Animal Virology,Ministry of Agriculture,State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "MA Li-na",
                "org": "Key Laboratory of Animal Virology,Ministry of Agriculture,State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "MA Yan-ping",
                "org": "Key Laboratory of Animal Virology,Ministry of Agriculture,State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "DING Yao-zhong",
                "org": "Key Laboratory of Animal Virology,Ministry of Agriculture,State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Key Laboratory of Animal Virology,Ministry of Agriculture,State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            }
        ],
        "venue": "Acta Agriculturae Jiangxi",
        "year": 2009
    },
    "OVFrb0o1": {
        "id": "OVFrb0o1",
        "title": "Stable Expression of Bovine Prion Protein in CHO/dhfr-cells",
        "abstract": "The target genes from T-vector were connected with dhfr co-amplified gene of eukaryotic vector and constructed pCI-PrP102.Purified recombinant plasmids were transferred into CHO/dhfr-cell through liposome,and obtained the stable expression of the cell strains after MTX screening,and indirect immunity fluorescence analysis detected the expression of the goal protein.",
        "keywords": [
            "Stable expression",
            "Bovine prion protein",
            "CHO/dhfr-cell"
        ],
        "authors": [
            {
                "name": "DING Yao-zhong",
                "org": "Gansu Agricultural University,Lanzhou ,China;Key Laboratory of Veterinary Public Health,Ministry of Agriculture"
            },
            {
                "name": "ZHANG Jie",
                "org": "Key Laboratory of Veterinary Public Health,Ministry of Agriculture"
            },
            {
                "name": "LIU Yong-sheng",
                "org": "Key Laboratory of Veterinary Public Health,Ministry of Agriculture"
            },
            {
                "name": "CHEN Hao-tai",
                "org": "Key Laboratory of Veterinary Public Health,Ministry of Agriculture"
            },
            {
                "name": "ZENG Qiao-ying",
                "org": "Gansu Agricultural University,Lanzhou ,China"
            },
            {
                "name": "MA Li-na",
                "org": "Key Laboratory of Veterinary Public Health,Ministry of Agriculture"
            },
            {
                "name": "MA Yan-ping",
                "org": "Key Laboratory of Veterinary Public Health,Ministry of Agriculture"
            },
            {
                "name": "YANG Sheng-hai",
                "org": "Key Laboratory of Veterinary Public Health,Ministry of Agriculture"
            }
        ],
        "venue": "Acta Agriculturae Jiangxi",
        "year": 2009
    },
    "BmpHlFU2": {
        "id": "BmpHlFU2",
        "title": "Molecular beacon technology and its application in biology",
        "abstract": "The investigation range of life science had reached the scale of nanometer and the level of single cell, single molecule.How to obtain the useful biochemical information on this scale is the new trend in all the research field.Novel molecular probe for real time and in vivo detection has been the focuses in the research field of biochemistry. This article is tell about the overview of molecular beacon and its use in molecular biology.",
        "keywords": [
            "Fluorescence probes",
            "Detection",
            "Molecular beacon"
        ],
        "authors": [
            {
                "name": "Yang Shenghai",
                "org": " Key Laboratory of Animal Virolog of, Ministry of Agriculture/State Key Laboratory of VeterinaryEtiological Biology/Lanzhou Veterinary Research Institute, Chinese Academy ofAgricul tural Sciences,Lanzhou ; China Agricultural Veterinarian Biolgy Science and Technology Co.Ltd., Lanzhou "
            },
            {
                "name": "Yin Hong",
                "org": " Key Laboratory of Animal Virolog of, Ministry of Agriculture/State Key Laboratory of VeterinaryEtiological Biology/Lanzhou Veterinary Research Institute, Chinese Academy ofAgricul tural Sciences,Lanzhou "
            },
            {
                "name": "Liu Yongsheng",
                "org": " Key Laboratory of Animal Virolog of, Ministry of Agriculture/State Key Laboratory of VeterinaryEtiological Biology/Lanzhou Veterinary Research Institute, Chinese Academy ofAgricul tural Sciences,Lanzhou "
            },
            {
                "name": "Chen Haotai",
                "org": " Key Laboratory of Animal Virolog of, Ministry of Agriculture/State Key Laboratory of VeterinaryEtiological Biology/Lanzhou Veterinary Research Institute, Chinese Academy ofAgricul tural Sciences,Lanzhou "
            },
            {
                "name": "Zhang Jie",
                "org": " Key Laboratory of Animal Virolog of, Ministry of Agriculture/State Key Laboratory of VeterinaryEtiological Biology/Lanzhou Veterinary Research Institute, Chinese Academy ofAgricul tural Sciences,Lanzhou "
            }
        ],
        "venue": "Modern Instruments",
        "year": 2009
    },
    "9JzEHJAQ": {
        "id": "9JzEHJAQ",
        "title": "Research Progress in Application of Transposon",
        "abstract": "Transposon is the basic unit of self-replication and shift in DNA,it exists in all fields of biology,transposon and its related technology are the powerful weapons for studying the function of the genome in the post-genome era.This article reviews the classification of transposon,the transposable mechanism of transposon,as well as the application and developmental prospects of transposon.",
        "keywords": [
            "Transposon",
            "Classification",
            "Application",
            "Transposable mechanism"
        ],
        "authors": [
            {
                "name": "MA Yan-ping",
                "org": "State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "LIU Yong-sheng",
                "org": "State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "DING Yao-zhong",
                "org": "State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "YANG Sheng-hai",
                "org": "State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            }
        ],
        "venue": "Acta Agriculturae Jiangxi",
        "year": 2009
    },
    "3Y0MJvzS": {
        "id": "3Y0MJvzS",
        "title": "Applications of Sensors in Detection of Pathogenic Bacteria",
        "abstract": "The immun-biosensor has characteristic of sensitiy, fleetness and economic ways which have applied in the industry, agriculture, environmental monitoring and biomedicine. This paper show that the immunity biosensor applicated in the S.aureu, the E.coli, V.parahaemolyticus and so on, and its developed in the future.",
        "keywords": [
            "microorganism",
            "detection",
            "immunity biosensor",
            "bacterium"
        ],
        "authors": [
            {
                "name": "Zhang Jie",
                "org": "Key Laboratory of Veterinary Public Health of Ministry of Agriculture, Key Laboratory of Animal Virology of Ministry of Agriculture, State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences,Lanzhou "
            },
            {
                "name": "Liu Yongsheng",
                "org": "Key Laboratory of Veterinary Public Health of Ministry of Agriculture, Key Laboratory of Animal Virology of Ministry of Agriculture, State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences,Lanzhou "
            }
        ],
        "venue": "Chinese Agricultural Science Bulletin",
        "year": 2010
    },
    "CtoR7Txk": {
        "id": "CtoR7Txk",
        "title": "Advances in the common identification methods of bacterial biofilm",
        "abstract": "The common identification methods for bacterial biofilm,including the glass tube method,silver staining,scanning electron microscopy,transmission electron microscopy,confocal laser scanning microscopy,and microtitre plate method,were reviewed in the aspects of the main steps and precautions,and the achievement of the biofilm research.The advantages and disadvantages of these methods were elucidated,and then the suggestions were proposed for offsetting the disadvantages of the methods.",
        "keywords": [
            "scanning electron microscope",
            "biofilm",
            "transmission electron microscope",
            "identification method"
        ],
        "authors": [
            {
                "name": "HU Jin-song",
                "org": "Key Laboratory of Veterinary Public Health of the Ministry of Agriculture/Key Laboratory of Animal Virology of the Ministry of Agriculture/State Key Laboratory of Veterinary Etiological Biology/Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China;Animal Biological Technological Center,Sichuan Agricultural University,Ya’an ,China"
            },
            {
                "name": "CHEN Hao-tai",
                "org": "Key Laboratory of Veterinary Public Health of the Ministry of Agriculture/Key Laboratory of Animal Virology of the Ministry of Agriculture/State Key Laboratory of Veterinary Etiological Biology/Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Key Laboratory of Veterinary Public Health of the Ministry of Agriculture/Key Laboratory of Animal Virology of the Ministry of Agriculture/State Key Laboratory of Veterinary Etiological Biology/Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "LIU Yong-sheng",
                "org": "Key Laboratory of Veterinary Public Health of the Ministry of Agriculture/Key Laboratory of Animal Virology of the Ministry of Agriculture/State Key Laboratory of Veterinary Etiological Biology/Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "XU Zhi-wen",
                "org": "Animal Biological Technological Center,Sichuan Agricultural University,Ya’an ,China"
            },
            {
                "name": "ZHU Ling",
                "org": "Animal Biological Technological Center,Sichuan Agricultural University,Ya’an ,China"
            },
            {
                "name": "XU Kai",
                "org": "Animal Biological Technological Center,Sichuan Agricultural University,Ya’an ,China"
            },
            {
                "name": "NIAN Yang-yang",
                "org": "Animal Biological Technological Center,Sichuan Agricultural University,Ya’an ,China"
            },
            {
                "name": "GU Feng",
                "org": "Animal Biological Technological Center,Sichuan Agricultural University,Ya’an ,China"
            }
        ],
        "venue": "Chinese Veterinary Science",
        "year": 2010
    },
    "sMjFc9zK": {
        "id": "sMjFc9zK",
        "title": "Progress in DNA Vaccine of Porcine Reproductive and Respiratory Syndrome",
        "abstract": "Porcine reproductive and respiratory syndrome is one of the most threatening important diseases, which causes serious economic loss of swine industry every year. There is not an effective measure to prevent PRRS today. Vaccine inoculation is the main method to prevent and control the disease. The focus of the vaccine research is genetic engineering vaccine. Especially, the DNA vaccine not only induces humoral immunity, but also stimulates high level of cellular immunity response. It is easy to manufacture and store up. Currently, preliminary results have been achieved in the research of DNA vaccine for PRRS. The progress in DNA vaccine of PRRS is summarized below.",
        "keywords": [
            "prevention",
            "DNA vaccine",
            "porcine reproductive and respiratory syndrome (PRRS)"
        ],
        "authors": [
            {
                "name": "Zhang Yiqiang",
                "org": " State Laboratory of Veterinary Etiological Biology , Key Laboratory of Animal Virology of Ministry of Agriculture , Key laboratory of Veterinary Public Health of Ministry of Agriculture , Lanzhou Veterinary Research Institute , Chinese Academy of Agricultural Sciences , Lanzhou "
            },
            {
                "name": "Wang Meng",
                "org": " State Laboratory of Veterinary Etiological Biology , Key Laboratory of Animal Virology of Ministry of Agriculture , Key laboratory of Veterinary Public Health of Ministry of Agriculture , Lanzhou Veterinary Research Institute , Chinese Academy of Agricultural Sciences , Lanzhou "
            },
            {
                "name": "Liu Yongsheng",
                "org": " State Laboratory of Veterinary Etiological Biology , Key Laboratory of Animal Virology of Ministry of Agriculture , Key laboratory of Veterinary Public Health of Ministry of Agriculture , Lanzhou Veterinary Research Institute , Chinese Academy of Agricultural Sciences , Lanzhou "
            },
            {
                "name": "Zhang Jie",
                "org": " State Laboratory of Veterinary Etiological Biology , Key Laboratory of Animal Virology of Ministry of Agriculture , Key laboratory of Veterinary Public Health of Ministry of Agriculture , Lanzhou Veterinary Research Institute , Chinese Academy of Agricultural Sciences , Lanzhou "
            }
        ],
        "venue": "Chinese Agricultural Science Bulletin",
        "year": 2010
    },
    "gABHDp9b": {
        "id": "gABHDp9b",
        "title": "Research Progress on Application of DNA Chip in Animal Medicine",
        "abstract": "With the increase of genome ’s numbers,DNA Chip technology gained widely application.Its merit of integration,miniaturization,and automation advantages supply a powerful tool in the field of biology,medicine,chemistry and other research.This article overview DNA chip technology from gene expression spectrum research,identification of pathogenic microbial detection,bacterial typing,genetic mutations and polymorphism detection,pathogenic microbial genomics research in animal medicine application progress,and the principle of DNA chip technology are reviewed.",
        "keywords": [
            "principle",
            "application",
            "animal medicine",
            "DNA Chip",
            "classification"
        ],
        "authors": [
            {
                "name": "Ma Yanping",
                "org": "State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou "
            },
            {
                "name": "Chen Haotai",
                "org": "State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou "
            },
            {
                "name": "Ma Lina",
                "org": "State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou "
            },
            {
                "name": "Zhou Jianhua",
                "org": "State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou "
            },
            {
                "name": "Zhang Jie",
                "org": "State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou "
            },
            {
                "name": "Ding Yaozhong",
                "org": "State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou "
            },
            {
                "name": "Wang Meng",
                "org": "State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou "
            },
            {
                "name": "Liu Yongsheng",
                "org": "State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou "
            }
        ],
        "venue": "Chinese Agricultural Science Bulletin",
        "year": 2010
    },
    "FGHKHkgt": {
        "id": "FGHKHkgt",
        "title": "Foot and Mouth Disease Virus Proteins and Apoptosis",
        "abstract": "Foot and mouth disease virus(FMDV) can induce or prevent the apoptosis of the host cell according to oneself needs in the process of infecting cells,so as to create the best living environment and to escape the attack from the host cells in a certain extent to obtain the maximize viability.This paper reviewed the different roles of the FMDV proteins in regulating host cell apoptosis homeostasis,and discussed the mechanism of FMDV persistence infection.",
        "keywords": [
            "TNF",
            "PKR",
            "eIF4G",
            "apoptosis"
        ],
        "authors": [
            {
                "name": "Wang Meng",
                "org": "Key laboratory of Veterinary Public Health of Agriculture,Key Laboratory of Animal Virology of Ministry of Agriculture,State Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou "
            },
            {
                "name": "Liu Yongsheng",
                "org": "Key laboratory of Veterinary Public Health of Agriculture,Key Laboratory of Animal Virology of Ministry of Agriculture,State Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou "
            },
            {
                "name": "Zhang Jie",
                "org": "Key laboratory of Veterinary Public Health of Agriculture,Key Laboratory of Animal Virology of Ministry of Agriculture,State Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou "
            }
        ],
        "venue": "Chinese Agricultural Science Bulletin",
        "year": 2010
    },
    "cLCOzJuW": {
        "id": "cLCOzJuW",
        "title": "Expression of Bovine Prion Protein in COS-7 Cell",
        "abstract": "In order to detect the expression of recombinant protein pCI-PrP27-30 in COS-7 cell,pCI-PrP27-30 was transferred into COS-7 cell,then stable cell line was obtained using G418 screening.Three kinds of techniques of indirect immunofluorescence assay,indirect enzyme linked immunosorbent assay and Western blot assay were used in detection of recombinant protein pCI-PrP27-30 expression in COS-7.The results showed that the expression was got successful.",
        "keywords": [
            "COS-7",
            "bovine prion protein(boprp)",
            "indirect immunofluorescence assay"
        ],
        "authors": [
            {
                "name": "DING Yao-zhong",
                "org": "Key Laboratory of Veterinary Public Health,Ministry of Agriculture,Key Laboratory of Animal Virology,Ministry of Agriculture,State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Key Laboratory of Veterinary Public Health,Ministry of Agriculture,Key Laboratory of Animal Virology,Ministry of Agriculture,State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "LIU Yong-sheng",
                "org": "Key Laboratory of Veterinary Public Health,Ministry of Agriculture,Key Laboratory of Animal Virology,Ministry of Agriculture,State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "CHEN Hao-tai",
                "org": "Key Laboratory of Veterinary Public Health,Ministry of Agriculture,Key Laboratory of Animal Virology,Ministry of Agriculture,State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "MA Li-na",
                "org": "Key Laboratory of Veterinary Public Health,Ministry of Agriculture,Key Laboratory of Animal Virology,Ministry of Agriculture,State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "MA Yan-ping",
                "org": "Key Laboratory of Veterinary Public Health,Ministry of Agriculture,Key Laboratory of Animal Virology,Ministry of Agriculture,State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "YANG Sheng-hai",
                "org": "Key Laboratory of Veterinary Public Health,Ministry of Agriculture,Key Laboratory of Animal Virology,Ministry of Agriculture,State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "WANG Meng",
                "org": "Key Laboratory of Veterinary Public Health,Ministry of Agriculture,Key Laboratory of Animal Virology,Ministry of Agriculture,State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "YIN Hong",
                "org": "Key Laboratory of Veterinary Public Health,Ministry of Agriculture,Key Laboratory of Animal Virology,Ministry of Agriculture,State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            }
        ],
        "venue": "Jiangsu Journal of Agricultural Sciences",
        "year": 2010
    },
    "SfZmDmaj": {
        "id": "SfZmDmaj",
        "title": "Research Progress and Application of the Structural Proteins of Porcine Reproductive and Respiratory Syndrome (PRRS) Virus",
        "abstract": "Porcine reproductive and respiratory syndrome virus (PRRSV) is a positive-strand RNA virus that belongs to the Arteriviridae family. The genomic RNA is approximately 15 kb. The genome encodes the RNA replicase (ORF1a and ORF1b), the glycoprotein (GP2 to GP5), the integral membrane protein M (ORF6), and the nucleocapsid protein N (ORF7). Each of the PRRSV structural proteins has a distinct role in virus infection, immune response etc. This thesis sums up the research and application of the structural proteins of porcine reproductive and respiratory syndrome (PRRS) virus.",
        "keywords": [
            "heterodimers",
            "minor structural protein",
            "immunogenicity",
            "glycoprotein"
        ],
        "authors": [
            {
                "name": "Wang Meng",
                "org": " Key laboratory of Veterinary Public Health of Agriculture , Key Laboratory of Animal Virology of Ministry of Agriculture , State Laboratory of Veterinary Etiological Biology , Lanzhou Veterinary Research Institute , Chinese Academy of Agricultural Sciences , Lanzhou "
            },
            {
                "name": "Liu Yongsheng",
                "org": " Key laboratory of Veterinary Public Health of Agriculture , Key Laboratory of Animal Virology of Ministry of Agriculture , State Laboratory of Veterinary Etiological Biology , Lanzhou Veterinary Research Institute , Chinese Academy of Agricultural Sciences , Lanzhou "
            },
            {
                "name": "Zhang Jie",
                "org": " Key laboratory of Veterinary Public Health of Agriculture , Key Laboratory of Animal Virology of Ministry of Agriculture , State Laboratory of Veterinary Etiological Biology , Lanzhou Veterinary Research Institute , Chinese Academy of Agricultural Sciences , Lanzhou "
            }
        ],
        "venue": "Chinese Agricultural Science Bulletin",
        "year": 2010
    },
    "0DypBqbg": {
        "id": "0DypBqbg",
        "title": "Advances in Research of Interferon-gamma",
        "abstract": "Interferon-gamma(IFN-γ)secreted by T lymphocytes and natural killer(NK)cells is an anti-viral and anti-tumor proliferation and immunoregulatory cytokine.It has powerful regulatory effects on immune system,and it is a necessary element in playing immune functions,scavenging pathogens in vivo.Therefore,IFN-γ plays more important roles in diagnosis,treatment of clinical diseases and in detecting immune efficacy of vaccines.It is one of the research focuses in the modern molecular biology,immunology and clinical medicine.This article summarized interferon-gamma briefly in following aspects,including production,structural characteristic,biological activity and physiological mechanism.",
        "keywords": [
            "Interferon-gamma Structural characteristic Biological activity"
        ],
        "authors": [
            {
                "name": "Yang Shenghai",
                "org": "Key Laboratory of Animal Virolog of Ministry of Agriculture,State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricul tural Sciences,Lanzhou ;China Agricultural Veterinarian Biolgy Science and Technology Co.Ltd.,Lanzhou "
            },
            {
                "name": "Yin Hong",
                "org": "Key Laboratory of Animal Virolog of Ministry of Agriculture,State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricul tural Sciences,Lanzhou "
            },
            {
                "name": "Liu Yongsheng",
                "org": "Key Laboratory of Animal Virolog of Ministry of Agriculture,State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricul tural Sciences,Lanzhou "
            },
            {
                "name": "Zhang Jie",
                "org": "Key Laboratory of Animal Virolog of Ministry of Agriculture,State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricul tural Sciences,Lanzhou "
            }
        ],
        "venue": "Biotechnology Bulletin",
        "year": 2010
    },
    "Hn7i5zHx": {
        "id": "Hn7i5zHx",
        "title": "Swine Influenza and Advances in Biological Characteristics of Swine Influenza",
        "abstract": "Swine Influenza (I) is the Zoonosis which causeed by the Influenza A virus,resently,has listed one of the most important infectious disease by OIE and Every Government,and threat of human being,s safety and production of animals.Meanwhile,which has many subtype,strong antigenic variation microorganism and wide host range.SIV's ecological and public hygienics significance already acquired mankind's highly concern,The Paper has summarized the biological characteristics and explored possible pathogenesis of SIV.",
        "keywords": [
            "swine Influenza",
            "biological characteristics",
            "influenza A virus"
        ],
        "authors": [
            {
                "name": "Ding Yaozhong",
                "org": "Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Lanzhou "
            },
            {
                "name": "Liu Yongsheng",
                "org": "Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Lanzhou "
            },
            {
                "name": "Chen Haotai",
                "org": "Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Lanzhou "
            },
            {
                "name": "Zhang Jie",
                "org": "Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Lanzhou "
            }
        ],
        "venue": "Chinese Agricultural Science Bulletin",
        "year": 2010
    },
    "BZMiMFsE": {
        "id": "BZMiMFsE",
        "title": "Detection and expression of recombinant protein PrP102-242 in COS-1 cells",
        "abstract": "To detect the expression of product of recombinant protein PrP102-242 in COS-1 cells,purified recombinant protein of PrP102-242 were transfected into COS-1 cells,to obtain stable cell lines using different concentration of G418.After that,the expression of recombinant protein PrP102-242 in COS-1 were detected by using indirect immunity fluorescence assay(in-IFA),indirect enzyme linked immunosorbent assay(in-ELISA)and Western blot assay.The result showed that expression of pCIp264 in COS-1 were detected by using in-ELISA,IFA and Western blot.",
        "keywords": [
            "indirect immunofluorescence",
            "COS-1",
            "prion protein(PrP)"
        ],
        "authors": [
            {
                "name": "DING Yao-zhong",
                "org": "Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Key Laboratory of Animal Virology of Ministry of Agriculture,Lanzhou ,China"
            },
            {
                "name": "LIU Yong-sheng",
                "org": "Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Key Laboratory of Animal Virology of Ministry of Agriculture,Lanzhou ,China"
            },
            {
                "name": "CHEN Hao-tai",
                "org": "Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Key Laboratory of Animal Virology of Ministry of Agriculture,Lanzhou ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Key Laboratory of Animal Virology of Ministry of Agriculture,Lanzhou ,China"
            }
        ],
        "venue": "Chinese Journal of Zoonoses",
        "year": 2010
    },
    "zGfpl2uS": {
        "id": "zGfpl2uS",
        "title": "Codon usage of the polyprotein coding sequence in foot and mouth disease virus serotype A and serotype O",
        "abstract": "Fifty five genes coding for polyproteins in foot and mouth disease virus (FMDV) serotype A and serotype O had been analyzed in term of variance analysis,in which 27 genes coding for polyproteins belonged to serotype A,the rest coding for polyproteins of serotype O. It had been observed that codon usage in different codons (including GCC,GCG,AGA,CGG,GGC,GGU,CAC,CAU,AUA,AUU,CUG,CCC,AGC,UCU,ACA,ACC,ACG,ACU) was significantly different. However,by analysis of the relative amino acid usage,it was found that only Ala,Arg,Leu,Phe,Ser were significant at the amino acid usage. These results indicate that the codon usage provides more informations than the amino acid usage. In addition,through analysis of the general pattern of codon usage between serotype A and serotype O,the comparison of the two serotypes with large amount of codons shows that the codon usage of two serotypes may be correspondent to tRNA abundance. Also these results put concept of \"relative synonymous codon usage\" (RSCU) into a novel perspective to mutation of FMDV. The internal connectivity of synonymous codons indicates that all synonymous codons may take part in some selection mechanisms.",
        "keywords": [
            "variance analysis",
            "foot and mouth disease virus",
            "codon usage",
            "relative synonymous codon usage",
            "relative amino acid usage"
        ],
        "authors": [
            {
                "name": "ZHOU Jian-hua",
                "org": "Chinese Academy of Agriculture Science,State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,National FMD Reference Laboratory,Lanzhou ,China"
            },
            {
                "name": "LIU Yong-sheng",
                "org": "Chinese Academy of Agriculture Science,State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,National FMD Reference Laboratory,Lanzhou ,China"
            },
            {
                "name": "CHEN Hao-tai",
                "org": "Chinese Academy of Agriculture Science,State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,National FMD Reference Laboratory,Lanzhou ,China"
            },
            {
                "name": "MA Li-na",
                "org": "Chinese Academy of Agriculture Science,State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,National FMD Reference Laboratory,Lanzhou ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Chinese Academy of Agriculture Science,State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,National FMD Reference Laboratory,Lanzhou ,China"
            }
        ],
        "venue": "Chinese Journal of Zoonoses",
        "year": 2010
    },
    "ciTg4dbc": {
        "id": "ciTg4dbc",
        "title": "Application of Reverse Genetics Manipulation in the Research of Porcine Reproductive and Respiratory Syndrome",
        "abstract": "Porcine reproductive and respiratory syndrome (PRRS),caused by porcine reproductive and respiratory syndrome virus (PRRSV),is considered one of the most important contagious diseases in swine industry today and responsible for significant economic losses worldwide.Reverse genetics manipulation has been used extensively in variety of fields of life science for several decades,which supported us a powerful method to explore organisms.This paper mainly summarized the application and perspective of reverse genetics manipulation in the research of PRRS,including virus rescue,vaccines development,molecular etiology diagnosis and so on.",
        "keywords": [
            "PRRS",
            "applications",
            "RNA virus",
            "reverse genetics manipulation",
            "virus rescue"
        ],
        "authors": [
            {
                "name": "Gu Yuanxing",
                "org": "Key laboratory of Veterinary Public Health of Agriculture,Key Laboratory of Animal Virology of Ministry of Agriculture,State Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou "
            },
            {
                "name": "Wang Meng",
                "org": "Key laboratory of Veterinary Public Health of Agriculture,Key Laboratory of Animal Virology of Ministry of Agriculture,State Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou "
            },
            {
                "name": "Liu Yongsheng",
                "org": "Key laboratory of Veterinary Public Health of Agriculture,Key Laboratory of Animal Virology of Ministry of Agriculture,State Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou "
            },
            {
                "name": "Zhang Jie",
                "org": "Key laboratory of Veterinary Public Health of Agriculture,Key Laboratory of Animal Virology of Ministry of Agriculture,State Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou "
            }
        ],
        "venue": "Chinese Agricultural Science Bulletin",
        "year": 2011
    },
    "x0WAKdCO": {
        "id": "x0WAKdCO",
        "title": "Detection of foot-and-mouth disease virus rna by reverse transcription loop-mediated isothermal amplification",
        "abstract": "A reverse transcription loop-mediated isothermal amplification (RT-LAMP) assay was developed for foot-and-mouth disease virus (FMDV) RNA. The amplification was able to finish in 45 min under isothermal condition at 64°C by employing a set of four primers targeting FMDV 2B. The assay showed higher sensitivity than RT-PCR. No cross reactivity was observed from other RNA viruses including classical swine fever virus, swine vesicular disease, porcine reproductive and respiratory syndrome virus, Japanese encephalitis virus. Furthermore, the assay correctly detected 84 FMDV positive samples but not 65 FMDV negative specimens. The result indicated the potential usefulness of the technique as a simple and rapid procedure for the detection of FMDV infection.",
        "keywords": [
            "sensitivity"
        ],
        "authors": [
            {
                "name": "Hao-tai Chen",
                "org": "State Key Laboratory of Veterinary Etiologic Biology,National Foot-and-Mouth Disease Reference Laboratory of China, Key laboratory of Animal Virology of Ministry of Agriculture, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences,,Lanzhou,P.R.China"
            },
            {
                "name": "zhang jie",
                "org": "State Key Laboratory of Veterinary Etiologic Biology,National Foot-and-Mouth Disease Reference Laboratory of China, Key laboratory of Animal Virology of Ministry of Agriculture, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences,,Lanzhou,P.R.China"
            },
            {
                "name": "Yong-sheng Liu",
                "org": "State Key Laboratory of Veterinary Etiologic Biology,National Foot-and-Mouth Disease Reference Laboratory of China, Key laboratory of Animal Virology of Ministry of Agriculture, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences,,Lanzhou,P.R.China"
            },
            {
                "name": "Xiang-tao Liu",
                "org": "State Key Laboratory of Veterinary Etiologic Biology,National Foot-and-Mouth Disease Reference Laboratory of China, Key laboratory of Animal Virology of Ministry of Agriculture, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences,,Lanzhou,P.R.China"
            }
        ],
        "venue": "Virology journal",
        "year": 2011
    },
    "sNxdwUob": {
        "id": "sNxdwUob",
        "title": "Advances in the Application of DNA Chip in Animal Medicine",
        "abstract": "Accompanying with the increasingly saturated genome figures,DNA chip has been widely applied.Thanks to its advantages of integration,miniaturization and automation,DNA chip becomes a powerful research tool in various research fields including biology,medicine and chemistry.This article overviews the application of DNA chip technology in animal medicine from gene expression spectrum research,pathogenic microbial detection,bacterial typing,genetic mutations and polymorphism detection,pathogenic microbial genomics research,as well as its principle and classification.",
        "keywords": [
            "principle",
            "dna chip",
            "classification",
            "application",
            "animal medicine",
            "livestock",
            "dna",
            "genomics",
            "genetic analysis",
            "genes",
            "gene expression"
        ],
        "authors": [
            {
                "name": "ma yanping",
                "org": ""
            },
            {
                "name": "chen haotai",
                "org": ""
            },
            {
                "name": "ma lina",
                "org": ""
            },
            {
                "name": "zhou jianhua",
                "org": ""
            },
            {
                "name": "zhang jie",
                "org": ""
            },
            {
                "name": "ding yaozhong",
                "org": ""
            },
            {
                "name": "wang meng",
                "org": ""
            },
            {
                "name": "liu wenqian",
                "org": ""
            },
            {
                "name": "liu yongsheng",
                "org": ""
            }
        ],
        "venue": "农业科学与技术(英文版)",
        "year": 2011
    },
    "qRRzmBYQ": {
        "id": "qRRzmBYQ",
        "title": "Sequence analysis of luxS gene of Haemophilus parasuis and homology modeling of 3D structure of the deduced protein",
        "abstract": "Haemophilus parasuis luxS gene was amplified by PCR,the purified PCR product(510 bp) was cloned into pMD18-T vector and transformed into competent cell E.coil DH5α,the positive recombinant plasmid was sequenced.The nucleotide and amino acid sequences were compared with the full-length sequence of the other five referred bacterial strains available on GenBank,identity was higher than 70%.The characteristics of deduced protein were predicted by ExPAsy software.The homology modeling of 3D structure was done by SWISS-Model of Swiss-PDB viewer.The Ramachandram Plot showed that the structure of modeled luxS protein was reasonable.",
        "keywords": [
            "luxS",
            "homology modeling",
            "Haemophilus parasuis",
            "sequence analysis"
        ],
        "authors": [
            {
                "name": "MA Yan-ping",
                "org": "State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China;Guangdong Public Laboratory of Veterinary Public Health,Institute of Veterinary Medicine,Guangdong Academy of Agricultural Sciences,Guangzhou ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "CHEN Hao-tai",
                "org": "State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "MA Li-na",
                "org": "State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "ZHAO Na",
                "org": "State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "DING Yao-zhong",
                "org": "State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "WANG Meng",
                "org": "State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "LIU Yong-sheng",
                "org": "State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture,Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            }
        ],
        "venue": "Chinese Journal of Veterinary Science",
        "year": 2011
    },
    "1OzXy6vq": {
        "id": "1OzXy6vq",
        "title": "Construction of truncated mutants of gene encoding bovine doppel and their expression in E.coli",
        "abstract": "Several monoclonal antibody(Mab) against bovine doppel(DPL) have been prepared by our laboratory.In order to identify the epitopes recognized by these Mabs,truncated mutants of genes encoding bovine DPL were developed through gene cloning and the corresponding recombinant proteins were generated by their expression in E.coli.The prepared fusion proteins could provide materials for the analysis of epitopes of the Mabs.Primers for cloning 9 truncated mutants were designed.The truncated mutants were cloned by polymerase chain reaction(PCR) and then transformed into E.coli DH5α after ligation with prokaryotic expression vector pET-30a(+).The recombinant plasmids identified by double-enzyme digestion and sequencing were introduced into host strain E.coli JM109 and E.coli BL21 and then induced to express with isoproplyl-β-D-thiogalactoside(IPTG).The molecular weight,relative expression level and reaction to polyclonal antibody against DPL of the fusion proteins were detected by SDS-PAGE,Western blot and indirect ELISA.9 truncated mutants of gene encoding bovine DPL were successfully constructed.6 out of 9 mutants were expressed at high level in E.coli with the induction of IPTG and could well react to the specific antibody againt DPL.The work would lay a material foundation for the analysis of epitopes recognized by the Mab prepared by our laboratory.",
        "keywords": [
            "bovine doppel",
            "Western blot",
            "ELISA",
            "truncated mutants"
        ],
        "authors": [
            {
                "name": "YANG Sheng-hai",
                "org": "Key Laboratory of Animal Virology of Ministry of Agriculture,State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China;China Agricultural Veterinarian Biology Science and Technology Co.Ltd.,Lanzhou ,China"
            },
            {
                "name": "YIN Hong",
                "org": "Key Laboratory of Animal Virology of Ministry of Agriculture,State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "LIU Yong-sheng",
                "org": "Key Laboratory of Animal Virology of Ministry of Agriculture,State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "MA Yan-ping",
                "org": "Key Laboratory of Animal Virology of Ministry of Agriculture,State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "DING Yao-zhong",
                "org": "Key Laboratory of Animal Virology of Ministry of Agriculture,State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "SUN Cai-qin",
                "org": "China Agricultural Veterinarian Biology Science and Technology Co.Ltd.,Lanzhou ,China"
            },
            {
                "name": "DING Xiao-li",
                "org": "Jiangsu Animal Husbandry and Veterinary College,Taizhou,Jiangsu ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Key Laboratory of Animal Virology of Ministry of Agriculture,State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            }
        ],
        "venue": "Chinese Journal of Veterinary Science",
        "year": 2011
    },
    "ijmMyi6k": {
        "id": "ijmMyi6k",
        "title": "The Application Prospects of Ovine Adenovirus287 Vector",
        "abstract": "Ovine adenovirus 287 has a unique genome organization with a length of 29 576bp.The genome is characterized distinctively by a high A/T content(66.4%),the lack of a typical El region,and a long redundant sequence.Three nonessential regions of the viral genome,where 6.3kb foreign genes can be inserted theoretically,have been identified.OAdV287 also has unique fiber and penton,where lacks the integrin-binding domain in penton or any other capsid protein.OAdV287 can infect a wide range of human and animal cell lines,but failing to replicate in non-ovine cell lines.In addition,OAdV287 vector can circumvent the pre-existing human adenoviruses immunity,and so have an efficient transfection.Currently,OAdV287 has become one of the research focuses among the animal adenoviruses vectors.",
        "keywords": [
            "Ovine adenovirus Genome structure Gene vector Applications"
        ],
        "authors": [
            {
                "name": "GU Yuan-xing",
                "org": "Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "WANG Meng",
                "org": "Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "LIU Yong-sheng",
                "org": "Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            }
        ],
        "venue": "China Biotechnology",
        "year": 2011
    },
    "YrLRIs4B": {
        "id": "YrLRIs4B",
        "title": "Experimental animal models of BALB / c mice infected with Streptococcus suis",
        "abstract": "Mice were infected with living Streptococcus suis by celiac injection and the clinical symptoms were observe.The cadavers of the infected mice were anatomized to observe the pathologic changes through pathologic section preparation.According to the results of the cultural characteristics,biochemistry properties and PCR verification,the strain was identified to be Streptococcus suis.Then the mice were died from the infection of Streptococcus suis.All organs and tissues of the mice presented typical septicemic pathologic changes,proving that mouse could be a good material for study of Streptococcus suis.",
        "keywords": [
            "BALB/c mice model",
            "Streptococcus suis",
            "pathological changes"
        ],
        "authors": [
            {
                "name": "ZHANG Yi-qiang",
                "org": "State Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture, Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences,Lanzhou ,China;Laboratory of Animal Quarantine,College of Animal Medical,Sichuan Agricultural University,Ya'an Sichuan ,China"
            },
            {
                "name": "LIU Yong-sheng",
                "org": "State Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture, Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "WANG Yin",
                "org": "Laboratory of Animal Quarantine,College of Animal Medical,Sichuan Agricultural University,Ya'an Sichuan ,China"
            },
            {
                "name": "YAO Xue-ping",
                "org": "Laboratory of Animal Quarantine,College of Animal Medical,Sichuan Agricultural University,Ya'an Sichuan ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "State Laboratory of Veterinary Etiological Biology,Key Laboratory of Animal Virology of Ministry of Agriculture, Key Laboratory of Veterinary Public Health of Ministry of Agriculture,Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            }
        ],
        "venue": "Chinese Journal of Zoonoses",
        "year": 2011
    },
    "JnZ1cl2R": {
        "id": "JnZ1cl2R",
        "title": "Research advances on flotillins.",
        "abstract": "The proteins of flotillin-1 and flotillin-2 were originally discovered in axon regeneration of goldfish retinal ganglion cells. They are generally used as marker proteins of lipid rafts and considered to be scaffolding proteins of lipid microdomains. Although they are ubiquitously expressed and well-conserved from fly to man, their exact functions remain controversial. In this review, we summarize the structure of flotillins and some functions of them, such as regulating axon regeneration, endocytosis, T cell activation, insulin signaling, membrane protein recruitment, roles in the progression of some diseases and so on.",
        "keywords": [
            "signal transduction",
            "virology",
            "membrane proteins"
        ],
        "authors": [
            {
                "name": "Feng Zhao",
                "org": "State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, 730046 Gansu, P.R. China."
            },
            {
                "name": "Jie Zhang",
                "org": "State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences,Lanzhou,P.R. China"
            },
            {
                "name": "Yong-Sheng Liu",
                "org": "State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences,Lanzhou,P.R. China"
            },
            {
                "name": "Li Li",
                "org": "The People's Government of Huaikou Town in Jintang County of Chengdu City,Chengdu,P.R. China"
            },
            {
                "name": "Ya-Li He",
                "org": "School of Public Health, Lanzhou university,Lanzhou,P.R. China"
            }
        ],
        "venue": "Virology journal",
        "year": 2011
    },
    "WxhVbfV7": {
        "id": "WxhVbfV7",
        "title": "Advance in marker protein of lipid raft flotillin-1",
        "abstract": "This article reviews the structure of gene and protein of flotillin-1 confirmed as a marker protein of lipid raft and its physiological functions in order to provide references for study on the relationship between flotillin-1 and some neurodegenerative diseases.",
        "keywords": [
            "flotillin-1",
            "signal transduction",
            "lipid raft"
        ],
        "authors": [
            {
                "name": "ZHAO Feng",
                "org": "State Key Laboratory of Veterinary Etiological Biology/Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "State Key Laboratory of Veterinary Etiological Biology/Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            }
        ],
        "venue": "Chinese Veterinary Science",
        "year": 2011
    },
    "g03bQKF3": {
        "id": "g03bQKF3",
        "title": "Advances in Treatment of Theileriosis by Artesunate",
        "abstract": "Artesunate is a derivative of antimalarial drug artemisinin,and was used in the veterinary clinic for the treatment of theileriosis of cattle,sheep and double buds piroplasmosis,the characteristics of pharmacokinetics of artesunate on different animals,the therapeutic effect of the clinical treatment of theileriosis,and the dangers of animal husbandry in China in the past two decades were reviewed.",
        "keywords": [
            "clinical treatment",
            "theileriosis",
            "artesunate",
            "clinical symptom"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Lanzhou Institute of Animal Science and Veterinary Pharmaceutics / Key Open Laboratory of New Veterinary Medicine Engineering,Chinese Academy of Agricultural Sciences,Lanzhou ,China;Faculty of Veterinary Medicine,Gansu Agricultural University,Lanzhou ,China"
            },
            {
                "name": "ZHANG Ji-yu",
                "org": "Lanzhou Institute of Animal Science and Veterinary Pharmaceutics / Key Open Laboratory of New Veterinary Medicine Engineering,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "LI Bing",
                "org": "Lanzhou Institute of Animal Science and Veterinary Pharmaceutics / Key Open Laboratory of New Veterinary Medicine Engineering,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "ZHOU Xu-zheng",
                "org": "Lanzhou Institute of Animal Science and Veterinary Pharmaceutics / Key Open Laboratory of New Veterinary Medicine Engineering,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            }
        ],
        "venue": "Hubei Agricultural Sciences",
        "year": 2011
    },
    "JSXoVLxz": {
        "id": "JSXoVLxz",
        "title": "Progress in entry mediators of porcine reproductive and respiratory syndrome virus",
        "abstract": "In order to explore the pathway of porcine reproductive and respiratory syndrome virus(PRRSV) invading into target cells,PRRSV cell tropism and biology function of entry mediators(heparan sulphate,sialoadhesin,CD163 and so on) were summarized.A general model of the entry process in porcine alveolar macrophage was proposed.",
        "keywords": [
            "sialoadhesin",
            "receptor",
            "porcine reproductive and respiratory syndrome virus",
            "heparan sulphate",
            "CD163"
        ],
        "authors": [
            {
                "name": "ZHANG Yi-qiang",
                "org": "Key Laboratory of Veterinary Public Health of the Ministry of Agriculture/Key Laboratory of Animal Virology of the Ministry of Agriculture/State Key Laboratory of Veterinary Etiological Biology/Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China;College of Veterinary Medicine,Sichuan Agricultural University,Ya'an ,China"
            },
            {
                "name": "LIU Yong-sheng",
                "org": "Key Laboratory of Veterinary Public Health of the Ministry of Agriculture/Key Laboratory of Animal Virology of the Ministry of Agriculture/State Key Laboratory of Veterinary Etiological Biology/Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            },
            {
                "name": "WANG Yin",
                "org": "College of Veterinary Medicine,Sichuan Agricultural University,Ya'an ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Key Laboratory of Veterinary Public Health of the Ministry of Agriculture/Key Laboratory of Animal Virology of the Ministry of Agriculture/State Key Laboratory of Veterinary Etiological Biology/Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou ,China"
            }
        ],
        "venue": "Chinese Veterinary Science",
        "year": 2011
    },
    "NDzhUkyp": {
        "id": "NDzhUkyp",
        "title": "Serotonin transporter gene polymorphism in irritable bowel syndrome]",
        "abstract": "To investigate the association of serotonin transporter (SERT) gene polymorphism with irritable bowel syndrome (IBS).The VNTRs and 5-HTTLPR polymorphism of SERT gene was assessed with polymerase chain reaction in 81 patients with IBS and 48 healthy subjects(HS).Compared with HS, IBS patients have a greater frequency of STin2.12/10 genotype in VNTRs region and a smaller frequency of STin2.12/12 genotype, however no significant difference was found in polymorphism of this region among the patients with C-IBS, D-IBS and A-IBS. We also found that the 5-HTTLPR allele L/L genotype occurred with greater frequency in C-IBS patients than in other two subgroups, whereas the L/S genotype occurred with smaller frequency in C-IBS. The frequency of association between 12/12 genotype and L/L genotype (12/12-L/L) in C-IBS was significantly higher than those in A-IBS and HS.The presence of STin2.12/10 genotype may be correlated with IBS. The presence of L/L genotype and 12/12-L/L genotype association in IBS patients carries an increased risk of C-IBS, whereas the presence of the L/S genotype carries an increased risk of D-IBS and A-IBS.",
        "keywords": [],
        "authors": [
            {
                "name": "Bang-mao Wang",
                "org": "Department of Gastroenterology, Tianjin Medical University Hospital, Tianjin 300052, China. bmwang@mail.zlnet.com.cn"
            },
            {
                "name": "Yu-ming Wang",
                "org": ""
            },
            {
                "name": "Wei-ming Zhang",
                "org": ""
            },
            {
                "name": "Qing-yu Zhang",
                "org": ""
            },
            {
                "name": "Wen-tian Liu",
                "org": ""
            },
            {
                "name": "Kui Jiang",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            }
        ],
        "venue": "Zhonghua nei ke za zhi",
        "year": 2004
    },
    "aj6iNi3k": {
        "id": "aj6iNi3k",
        "title": "Expression of COX-2 in Barrett's esophagus and esophageal adenocarcinoma and its significance",
        "abstract": "AIM: To explore the significance of cyclooxygenase-2 (COX-2) expression and prostaglandin E2 (PGE2) level in human Barrett's esophagus (BE) and esophageal adenocarcinoma (EAC). METHODS: The expression of COX-2 mRNA, the distribution of COX-2 protein, and the content of PGE2 were detected in the endoscopic biopsies of from BE (n = 16), EAC (n = 17), and normal controls (n=20) by reverse transcription polymerase chain reaction (RT-PCR), immunohistochemistry, and radioimmunoassay (RIA), respectively. RESULTS: The positive rate of COX-2 mRNA was 87.50% (14/16) and 88.24% (15/17) in BE and EAC patients, respectively, which were significantly higher than that in the normal controls (25%, P<0.01). Furthermore, COX-2 protein was expressed in the epithelial cytoplasm of BE patients (81.25%, 13/16) and the plasm of cancer cells in EAC patients (76.47%, 13/17), which were significantly higher than that in the normal controls (20.00%, 4/20). The contents of PGE2 (ng/g) in BE (541.41±34.30) and EAC patients (559.22±37.77) were also significantly higher than those in the normal controls (357.10±37.58) (P<0.05). No significant difference was found between BE and EAC patients in COX-2 mRNA, protein expression and PGE2 content (P>0.05). CONCLUSION: COX-2 mRNA and its protein are over-expressed, and the level of PGE2 is increased in BE and EAC group. COX-2 and PGE2 may be involved in the development of Barrett's esophagus and esophageal adenocarcinoma.",
        "keywords": [
            "Cyclooxygenase-2",
            "Barrett's esophagus",
            "Prostaglandin E2",
            "Esophageal adenocarcinoma"
        ],
        "authors": [
            {
                "name": "Xin-Juan Liu",
                "org": ", Department of Gastroenterology, General Hospital of Tianjin Medical University, Tianjin , China"
            },
            {
                "name": "Bang-Mao Wang",
                "org": ", Department of Gastroenterology, General Hospital of Tianjin Medical University, Tianjin , China"
            },
            {
                "name": "Xue-Yan Yan",
                "org": ", Department of Gastroenterology, General Hospital of Tianjin Medical University, Tianjin , China"
            },
            {
                "name": "Zong-Shun L",
                "org": ", Department of Gastroenterology, General Hospital of Tianjin Medical University, Tianjin , China"
            },
            {
                "name": "Jie Zhang",
                "org": ", Department of Gastroenterology, General Hospital of Tianjin Medical University, Tianjin , China"
            }
        ],
        "venue": "orld Chinese Journal of Digestology",
        "year": 2005
    },
    "5HW3sGX8": {
        "id": "5HW3sGX8",
        "title": "Determination of 9-nitro-camptothecin in human plasma by HPLC",
        "abstract": "OBJECTIVE To establish an HPLC method for the determination of 9-nitro-camptothecin in human plasma.METHODS A kromasil C 18 column was used as analytical column.The mobile phase consisted of methanol and phosphate buffer solution(48∶52,pH 2.5).The flow rate was 1.0 mL·min -1 and the column temprature was at 30 ℃.Detection wavelength was at 370 nm.Camptothecin was used as internal standard.Plasma samples were prepared with solid phase extraction assay.RESULTS A linear calibration curve of 9-nitro-camptothecin in plasma was obtained in the concentration range of 5 to 1 000 μg·L -1(r= 0.999 9).The absolute recovery was between 83.5%- 114.4% and the relative recovery is between 84.0%- 104.9%.The intra- and inter-run precision was measured to be below 15%.CONCLUSION The method is shown to be convenient and accurate,and suitable for clinical pharmacokinetic study of 9-nitro-camptothecin.",
        "keywords": [
            "HPLC",
            "solid phase extraction",
            "9-nitro-camptothecin(9-NC)"
        ],
        "authors": [
            {
                "name": "YAN Zhao",
                "org": "State Institution of Drug Clinical Trial,Tianjin Cancer Hospital of Tianjin Medical University,Tianjin ,China"
            },
            {
                "name": "WANG Hua-qing",
                "org": "State Institution of Drug Clinical Trial,Tianjin Cancer Hospital of Tianjin Medical University,Tianjin ,China"
            },
            {
                "name": "ZHANG Rong-rong",
                "org": "Tianjin Medical University,Tianjin ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Tianjin Medical University,Tianjin ,China"
            },
            {
                "name": "HAO Xi-shan",
                "org": "State Institution of Drug Clinical Trial,Tianjin Cancer Hospital of Tianjin Medical University,Tianjin ,China"
            }
        ],
        "venue": "Chinese Journal of Hospital Pharmacy",
        "year": 2006
    },
    "AWMv8TSP": {
        "id": "AWMv8TSP",
        "title": "Expression of human β-defensin 2(hBD-2) in Helicobacter pylori induced gastritis",
        "abstract": "Objective: To detect the expression of human β-defensin 2(hBD-2) in Helicobacter pylori induced gastritis and to evaluate the antibacterial role of hBD-2 against H. pylori infection in gastric mucosa. Methods: Biopsied gastric mucosa specimens from H. pylori positive(n = 10) and H. pylori negative(n = 8) individuals were used. H. pylori was detected by urease test and histological examination. Expression of hBD-2 were examined by reverse transcription- polymerase chain reaction (RT-PCR). Results: Eighty percent of H. pylori positive specimens expressed a high level of hBD-2 mRNA while 25% H. pylori negative specimens expressed hBD-2 mRNA. Conclusion: H. pylori infection induced the expression of hBD-2 in gastric mucosa. It is suggested that hBD-2 plays an antibacterial role in H. pylori induced gastritis.",
        "keywords": [
            "Gastritis",
            "Helicobacter pylori",
            "Human β-defensin 2"
        ],
        "authors": [
            {
                "name": "Kui Jiang",
                "org": "Tianjin Medical University(Tianjin Medical University),Tianjin,China"
            },
            {
                "name": "WANG Bang-mao",
                "org": "Tianjin Medical University(Tianjin Medical University),Tianjin,China"
            },
            {
                "name": "LIU Xin-juan",
                "org": "Tianjin Medical University(Tianjin Medical University),Tianjin,China"
            },
            {
                "name": "YAN Xue-yan",
                "org": "Tianjin Medical University(Tianjin Medical University),Tianjin,China"
            },
            {
                "name": "Qing Ma",
                "org": "Tianjin Medical University(Tianjin Medical University),Tianjin,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Tianjin Medical University(Tianjin Medical University),Tianjin,China"
            }
        ],
        "venue": "Chinese Journal of Microbiology and Immunology",
        "year": 2006
    },
    "Okcz0Exw": {
        "id": "Okcz0Exw",
        "title": "The utility of capsule endoscopy in the diagnosis of obscure gastrointestinal bleeding of the elderly",
        "abstract": "Objective To evaluate the effectiveness of M2A capsule endoscopy in the diagnosis of obscure gastrointestinal bleeding of elder patients. Methods Capsule endoscopy was used in 27 elderly patients, who were suspected of small bowel bleeding because of obscure gastrointestinal bleeding. About 20 of the 27 patients underwent gastroscopy, colonoscopy or air-baricum double contrast examination, but none of the examinations confirmed the bleeding sites, whereas the other 5 patients didn't receive any examination because of their intolerance. Results M2A capsule endoscopy disclosed the sites of small bowel disorders in 20 out of the 27 patients, the positive rate was about 74. 1%. The pathological findings consisted of angiodysplasia in 6 cases, mutipolypi in the intestine in 4, and 1 of them was diagnosed rare Cronkhite-Canada syndrome, prominency in the intestine in 4, single or multiple ulcers in the intestine in 7, diffuse mucosa lesion in the intestine in 9 and diverticulum in 1, arteriolar bleeding in gastric in 2, gastric mucosa erosion or ulcer in 5, whereas 7 patients were in negative findings. There were 12 patients in whom appeared at least 2 sites of pathological changes. Conclusions This study demonstrates that capsule endoscopy provides an excellent visualization way for the small intestines, especially when the elder patients suffers obscure gastrointestinal bleeding. It is safe and usefull for evaluating the suspected small bowel bleeding.",
        "keywords": [
            "Gastrointestinal hemorrhage",
            "digestive system",
            "Endoscopy"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": ",LIU Wen-tian. Department of Gastroenterology,Tian jin Medical University General Hospital,Tianjin ,China"
            },
            {
                "name": "WANG Bang-mao",
                "org": ",LIU Wen-tian. Department of Gastroenterology,Tian jin Medical University General Hospital,Tianjin ,China"
            },
            {
                "name": "CAO Xiao-cang",
                "org": ",LIU Wen-tian. Department of Gastroenterology,Tian jin Medical University General Hospital,Tianjin ,China"
            }
        ],
        "venue": "Chinese Journal of Geriatrics",
        "year": 2006
    },
    "c7jNoY4L": {
        "id": "c7jNoY4L",
        "title": "Expression of Cdx2 and MUC2 in reflux esophagitis barrett's esophagus and esophageal adenocarcinoma",
        "abstract": "Objective In order to investigate the relationship among reflux esophagitis,Barrett's e- sophagus and esophageal adenocarcinomas,the expressions of Cdx2 and MUC2 gene were studied.Methods Using immunohistochemistry,the expressions of the Cdx2 and MUC2 were detected in the esophageal mu- cosa of 30 patients with reflux esophagitis,18 patients with Barrett's esophagus and 25 patients with esopha- geal adenocareinoma.Results The positive rate and staining intensity of Cdx2 and MUC2 expressions in re- flux esophagitis,Barrett's esophagus and esophageal adenocarcinoma were significantly higher than those in normal esophageal mucosa(P<0.05).Cdx2 was expressed in 26.7% patients with reflux esophagitis, 66.7% patients with Barrett's esophagus,and 28% patients with esophageal adenocarcinoma,whereas,it was negative in the normal esophageal mucosa.Expression of Cdx2 in Barrett's esophagus was significantly higher than that in reflux esophagitis(P<0.05).Expression of Cdx2 in esophageal adenocarcinoma was lower than that in Barrett's esophagus significantly(P<0.05).MUC2 expression was negative in the normal esophageal mucosa and reflux esophagitis,while it was positive in 61.1% patients with Barrett's esophagus,and in 24% patients with esophageal adenocarcinoma.The expression of MUC2 in esophageal adeuocarcinoma was signifi- cantly lower than that in Barrett's esophagus(P<0.05).The expression of Cdx2 had a similar pattern with MUC2.Conclusion Cdx2 is a trigger of intestinal metaplasia,while MUC2 is a later event of intestinal met- aplasia.This study on the expression of Cdx2 and MUC2 in the three kinds of esophageal lesion deduces that there is a close relationship among them.",
        "keywords": [
            "MUC2",
            "Cdx2",
            "Barrett'sesophagus",
            "Esophagitisreflux",
            "Esophagealcancer"
        ],
        "authors": [
            {
                "name": "LI Shu",
                "org": " FANG We-li. Department of Gastroenterology,General Hospital of Tianjin Medical University,Tianjin ,China"
            },
            {
                "name": "WANG Bang-mao",
                "org": " FANG We-li. Department of Gastroenterology,General Hospital of Tianjin Medical University,Tianjin ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": " FANG We-li. Department of Gastroenterology,General Hospital of Tianjin Medical University,Tianjin ,China"
            }
        ],
        "venue": "Chinese Journal of Digestive Endoscopy",
        "year": 2006
    },
    "fvRCCfaO": {
        "id": "fvRCCfaO",
        "title": "Expression of cyclooxygenase-2 in esophageal carcinoma",
        "abstract": "Objective To study the significance of cyclooxygenase_2 (COX-2) expression in human adenocarcinoma (EAC) and squamous cell carcinoma of esophagus (SCC), and explore the role of COX-2 in the prevention of esophagus cancer.Methods Using RT-PCR, immunohistochemistry and RIA, the expression of COX-2 mRNA, the distribution of COX-2 protein and the content of PGE_2 were investigated in endoscopy biopsies of 17 EAC and 22 SCC.Results COX-2 mRNA was positive in 88.24% of EAC and 72.73% of SCC, while in 25% of normal control (P<0.01). No significant differences of COX-2 mRNA were found between EAC and SCC. Further more, immunohistochemical staining for COX-2 expression was positive in the cytoplasm of EAC (76.47%) and SCC (72.73%). No significant differences of COX-2 expression were found between EAC and SCC. Mean PGE_2 levels were significantly higher in EAC(559.22±37.77) and SCC (563.52±41.12)compared with control(357.10±37.58)(P<0.05). No significant differences of PGE_2 levels were found between EAC and SCC.Conclusion Overexpression of COX-2 and its mRNA in EAC and SCC. PGE_2 levels were higher in EAC and SCC.",
        "keywords": [
            "COX-2",
            "Esophageal adenocarcinoma",
            "Squamous cell carcinomas"
        ],
        "authors": [
            {
                "name": "WANG Bangmao",
                "org": " General Hospital of Tianjin University,Tianjin ,China"
            },
            {
                "name": "LIU Xinjuan",
                "org": " General Hospital of Tianjin University,Tianjin ,China"
            },
            {
                "name": "YAN Xueyan",
                "org": " General Hospital of Tianjin University,Tianjin ,China"
            },
            {
                "name": "JIANG Kui",
                "org": " General Hospital of Tianjin University,Tianjin ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": " General Hospital of Tianjin University,Tianjin ,China"
            }
        ],
        "venue": "Chinese Journal of Gastroenterology and Hepatology",
        "year": 2006
    },
    "ouN6Ytjq": {
        "id": "ouN6Ytjq",
        "title": "Clinical analysis of 32 Chinese patients of Cronkhite-Canada syndrome.",
        "abstract": "Objective To update the knowledge of Cronkhite-Canada syndrome(CCS)by analysis of clinical charac- ters of Chinese patients.Methods Clinical data of 32 chinese patients of CCS in recent 20 years were reviewed.Re-. sults The characters of CCS were gastrointestinal polyposis with ectodermal symptomatology.Diarrhea,bellyache, weight loss,anaemia and edema were common features.Cancer was reported in 2 patients.Some patients had symptom- atic response to combination therapy.There may be racial or regional differences in CCS susceptibility but nation or folk detail information was concerned in neither Chinese nor other English language lecture.Novel appliance casted light on CCS,such as 99mTc-HSA scan,double-balloon enterscopy and WCE.Conclusion There is resemblance between Chinese and European or Japanese patients.Novel appliance,case report standardization and sharing database could promote the understanding of rare CCS.",
        "keywords": [
            "Diagnosis",
            "Therapy",
            "Clinical analysis",
            "Cronkhite-Canada syndrome",
            "Chinese"
        ],
        "authors": [
            {
                "name": "Wang Bangmao",
                "org": ".Departments of Gastroenterology of Tianjin Medical University Hospital Tianjin Medical University,Tianjin ,China"
            },
            {
                "name": "Zhang Jie",
                "org": ".Departments of Gastroenterology of Tianjin Medical University Hospital Tianjin Medical University,Tianjin ,China"
            },
            {
                "name": "Naixia Huang",
                "org": ".Departments of Gastroenterology of Tianjin Medical University Hospital Tianjin Medical University,Tianjin ,China"
            }
        ],
        "venue": "Chinese Journal of Practical Internal Medicine",
        "year": 2006
    },
    "X5ci22mB": {
        "id": "X5ci22mB",
        "title": "Application of Capsule Endoscopy in the diagnosis of gastrointestinal diseases",
        "abstract": "Objective To assess the capsule endoscopy in the diagnosis of gastrointestinal diseases, especially in the small intestine diseases.Methods 74 patients received examination by M2A capsule en- doscopy from February 2004 to February 2006.They were 53 patients had been checked by gastroscopy and colonoscopy,but the results were negative in 41 patients,and 12 patients left had chronic gastritis or gastric polypi or colonic polypi.In all 53 patients,30 of them were obscure gastrointestinal bleeding and 23 were abdominal pain or diarrhea.Results 23 of the 30 patients with obscure gastrointestinal bleeding (76.67%) were diagnosed intestinal lesion.The diseases included intestinal Crohn's disease 5,angiodysplasia 6,intes- tinal mucosa erosion 11,intestine apophysis 5 in which 3 of them were intestinal tumor approved by surgical operations,Cronkhite-Canada syndrome 1 and intestinal diverticulum 1.In the 23 patients who suffered from abdominal pain or diarrhea,15 of 23 (65.22%) were diagnosed small intestine diseases by capsule endos- copy,including intestinal mueosa erosion 8,single or multiple little ulcers in the end of ileum 7,multipolypi in small intestine 5.Some of the patients had more than 2 kinds of lesions.In 21 healthy people,only 1 per- son had multipolypoid,2 of them had inflammation in the small intestines,8 of them had gastric diseases, and the other 10 persons were completely normal.In all suspected small intestinal disease patients,the diag- nostic positive rate was 71.69% (38/53) by M2A capsule endoscopy.The diagnostic positive rate of M2A capsule endoscopy in the patients with obscure gastrointestinal bleeding was slightly higher than that in the patients with abdominal pain,but the trend was not significant.In the patients with obscure gastrointestinal bleeding,the gastric empty time,intestinal transit time and the total time of the M2A stayed in alimentary tract were significantly shorter than that in control group.The images of M2A capsule endoscopy were clear, and nobody felt uncomfortable or had complications during the processes.All of the capsules were discharged successfully in one week.Conclusion M2A capsule endoscopy with its high diagnostic rates and salty may be a good method in the diagnosis of small intestinal diseases,especially in the patients with obscure gastro- intestinal bleeding.",
        "keywords": [
            "Diagnosis",
            "Small intestinal diseases",
            "Gastrointestinal bleeding",
            "Capsule endoscopy"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": " LIU Wen-tian Department of Gastroenterology,TianJin Medcial University General Hospital,TianJin ,China"
            },
            {
                "name": "WANG Bang-mao",
                "org": " LIU Wen-tian Department of Gastroenterology,TianJin Medcial University General Hospital,TianJin ,China"
            },
            {
                "name": "YAN Xue-yan",
                "org": " LIU Wen-tian Department of Gastroenterology,TianJin Medcial University General Hospital,TianJin ,China"
            }
        ],
        "venue": "Chinese Journal of Digestive Endoscopy",
        "year": 2007
    },
    "TyHGsdsv": {
        "id": "TyHGsdsv",
        "title": "Immunological Mechanism of Chronic Gastritis in Graves' Disease Patients with Hyperthyroidism",
        "abstract": "Objective: To explore the expression of TSH-β and TSH-R genes in the stomach and duodenum in Graves' disease with hyperthyroidism. Methods: The cDNA of TSH-β and TSH-R gene fragments were successfully derived from gastric and duodenum tissues of Graves' disease patients with hyperthyroidism (the experimental group) by reverse transcript - polymerase chain reaction, and patients with only chronic gastritis were in control group. The TSH-R positive cells were detected in the gastric and duodenum tissues by immunohistochemistry. The number of the positive cells were counted in both Graves' disease patients with hyperthyroidism and the controls. Results: mRNAs of TSH-β and TSH-R gene were expressed in the gastric and duodenum tissues of patients with or without Graves' disease. The TSH-β gene expressed in the two sites of the patients with hyperthyroidism were significantly lower than those in the controls, whereas the TSH-R genes expression in the gastric and duodenum seemed to be significantly more than that in the controls. The TSH-R positive cells in the stomach and duodenum in patients with Graves' disease were remarkably more than that in the controls. Conclusion: The gastrointestinal abnormalities in patients with Graves' disease may be related with the local autoimmune injuries and endocrinopathy. Our study will pave a way for the further investigation on the correlation between Graves' disease and chronic gastritis.",
        "keywords": [
            "thyrotropin stromal cells immunohistochemistry gastritis chronic disease",
            "beta subunit receptors",
            "Graves' disease thyrotropin"
        ],
        "authors": [
            {
                "name": "Zhang Jie",
                "org": " Department of Gastroenterology, Tianjin Medical University General Hospital, Tianjin, , China."
            },
            {
                "name": "Wang Bangmao",
                "org": " Department of Gastroenterology, Tianjin Medical University General Hospital, Tianjin, , China."
            },
            {
                "name": "Lü Zongshun",
                "org": " Department of Gastroenterology, Tianjin Medical University General Hospital, Tianjin, , China."
            },
            {
                "name": "Qiu Mingcai",
                "org": " Department of Gastroenterology, Tianjin Medical University General Hospital, Tianjin, , China."
            }
        ],
        "venue": "Tianjin Medical Journal",
        "year": 2007
    },
    "vLafKoYv": {
        "id": "vLafKoYv",
        "title": "The Diagnostic Effect of Capsule Endoscopy in Obscure Gastrointestinal Bleeding",
        "abstract": "Objective:To evaluate the effectiveness of M2A capsule endoscopy in patients with obscure gastrointestinal bleeding,especially in intestinal hemorrhage.Methods:From February 2004 to March 2007,Given(M2A) capsule endoscopy system was used in 86 patients,who were suspected of small bowel bleeding.The patients were 7 to 85 years old,most of them(69/86) underwent gastroscopy,colonoscopy or air-baricum double contract examination,but all of them were negative.The others(17/86) didn't receive any examinations because of their intolerance.Result:About 71 of the 86 patients were found the bleeding sites in gastric mucosa,small intestine or colon by capsule endoscopy,the total diagnostic rate is 82.56%(71/86).Among the patients,approximately 44.19% persons were found disorder in gastric(38/86).The disorders include arteriolar bleeding in gastric 6,gastric mucosa erosion or ulcer 19,prominence or polipi in gastric 13.It disclosed small bowel pathologic findings in 62 out of 86 patients(72.09%).The findings consisted of angiodysplasia 12,mutipolypi in the intestine 8,and 1 of them was diagnosed Cronkhite-Canada syndrome,prominence in the intestine 11,single or multiple ulcers in the intestine 13,whatever 7 of them were diagnosed intestinal Crohn's disease,diffuse mucosa lesion in the intestine 27 and diverticulum 4.In addition,there were 4 patients were detected prominency in colon 4,whereas 15 patients were not found any change in their gastrointestinal tracts.It was the true that about 26 patients appeared 2 sites or more then 2 sites pathological changes.Conclusion:This study demonstrated that capsule endoscopy provided an excellent visualization way for the intestines,especially when the patients suffered obscure gastrointestinal bleeding.It was safety and usefulness for evaluating suspected small bowel bleeding.",
        "keywords": [
            "Small intestinal disease",
            "Obscure gastrointestinal bleeding",
            "Capsule endoscopy"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": " LIU Wen-tian Department of Gastroenterology,TianJin Medcial University General Hospital "
            },
            {
                "name": "WANG Bang-mao",
                "org": " LIU Wen-tian Department of Gastroenterology,TianJin Medcial University General Hospital "
            },
            {
                "name": "CAO Xiao-cang",
                "org": " LIU Wen-tian Department of Gastroenterology,TianJin Medcial University General Hospital "
            }
        ],
        "venue": "Digestive Disease and Endoscopy",
        "year": 2007
    },
    "gFqu9niU": {
        "id": "gFqu9niU",
        "title": "Expression of ghrelin in antrum mucosa of Helicobacter pylori-positive patients with chronic gastritis",
        "abstract": "Objective To detect the expression of ghrelin in the antrum mucosa of Helicobacter pylori(Hp) positive patients with chronic gastritis.Methods The gastric antrum mucosa specimens of Hp positive(n=10) and Hp negative(n=8) patients with chronic gastritis were obtained by gastroscopy.The presence of Hp was assured by rapid urease test and histology.Expression of ghrelin mRNA was detected by reverse transcription polymerase chain reaction(RT-PCR).Results Among 18 cases,Hp positive was in 10 cases,Hp negative was in 8 cases.Among 10 Hp positive cases,7 cases had a high level mRNA of ghrelin.However,a low level mRNA of ghrelin was found in 3 cases among 8 Hp negative cases(P=0.004).Conclusion The expression of a high level ghrelin mRNA was found in the antrum mucosa of Hp-positive patients with chronic gastritis,which suggested that ghrelin plays a role in gastrointestinal disfunction in the patients with chronic gastritis.",
        "keywords": [
            "ghrelin",
            "gastritis",
            "helicobacter pylori"
        ],
        "authors": [
            {
                "name": "ZHENG Zhong-qing",
                "org": "Department of Gastrointestinal Medicine,General Hospital,Tianjin Medical University,Tianjin,,China"
            },
            {
                "name": "WANG Bang-mao",
                "org": "Department of Gastrointestinal Medicine,General Hospital,Tianjin Medical University,Tianjin,,China"
            },
            {
                "name": "MA Qing",
                "org": "Department of Gastrointestinal Medicine,General Hospital,Tianjin Medical University,Tianjin,,China"
            },
            {
                "name": "JIANG Kui",
                "org": "Department of Gastrointestinal Medicine,General Hospital,Tianjin Medical University,Tianjin,,China"
            },
            {
                "name": "LIU Xin-juan",
                "org": "Department of Gastrointestinal Medicine,General Hospital,Tianjin Medical University,Tianjin,,China"
            },
            {
                "name": "YAN Xueyan",
                "org": "Department of Gastrointestinal Medicine,General Hospital,Tianjin Medical University,Tianjin,,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Gastrointestinal Medicine,General Hospital,Tianjin Medical University,Tianjin,,China"
            }
        ],
        "venue": "Clinical Focus",
        "year": 2007
    },
    "rzewkT7M": {
        "id": "rzewkT7M",
        "title": "TSH-βand TSH receptor gene expressions in ileum and colon of patients with Graves′disease accompanied by diarrhea",
        "abstract": "Objective To explore the pathogenesis of diarrhea in Graves′disease.Methods TSH-βand TSH receptor(TSHR)gene expressions of ileum and colon tissues were assayed in patients with Graves′disease accompanied by diarrhea(GD group)and in irritable bowel syndrome-diarrhea dominating patients(IBS-D group) by RT-PCR,and TSHR positive cells were detected in both ileum and colon tissues by immunohistoehemistry. Results Both TSH-βand TSHR genes were expressed in ileum and colon tissues of patients in 2 groups.Moreover, the TSH-βgene expression of colon in GD group(0.137±0.012)was significantly lower than that in IBS-D group(0.209±0.015,P<0.05);whereas the TSHR gene expression of colon in GD group(0.251±0.017) was significantly higher than that in IBS-D group(0.181±0.012,P<0.05);meanwhile,the expressions of TSH-βand TSHR genes of the ileum in GD group(0.109±0.012 and 0.142±0.015)did not show difference from those in 1BS-D group(0.124±0.010 and 0.096±0.005).The number of TSHR positive cells in the ileum showed no difference between two groups(44±6/Hp vs 42±7/Hp),whereas the number of TSHR positive cells in the colon showed remarkably difference between two groups[(83±8)/Hp vs(56±9)/Hp,P<0.05]. Conclusion TSH-βand TSHR gene express in ileum and colon of two groups,suggesting that the bowel symptoms in patients with Graves′disease are related with the local endocrine and autoimmune abnormalities.",
        "keywords": [
            "Diarrhea",
            "thyrotropin",
            "Receptors",
            "Thyrotropin",
            "Hyperthyroidism"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": " L1ANG Dong-chun Department of Internal Medicine,Tianjin Medical University General Hospital,Tianjin ,China"
            },
            {
                "name": "WANG Bang-mao",
                "org": " L1ANG Dong-chun Department of Internal Medicine,Tianjin Medical University General Hospital,Tianjin ,China"
            },
            {
                "name": "QIU Ming-cai",
                "org": " L1ANG Dong-chun Department of Internal Medicine,Tianjin Medical University General Hospital,Tianjin ,China"
            }
        ],
        "venue": "Chinese Journal of Endocrinology and Metabolism",
        "year": 2007
    },
    "FiITmiEa": {
        "id": "FiITmiEa",
        "title": "Study on the Distribution of Ursolic Acid Phospholipid Nanoparticle Injection in Mice",
        "abstract": "Objective:To investigate the distribution of Ursolic Acid Phospholipid Nanoparticles(UA-PL-NP) in mice.Methods:Kunming mice were injected UA-PL-NA through caudal veins,and the plasma and the main tissues of these mice were collected at 5 min,1 h and 4 h after injection,respectively.RP-HPLC method was used to determine the concentrations of UA in the plasma and the main tissues.Results:(1) UA mainly distributed in liver and gastrointestinal tissues.(2) A linear increase was noted with increasing concentrations of UA in the main tissues.(3) UA concentration decreased rapidly in gas-trointestinal tissue,and only an extremely low concentration was remained at 4 h after injection.UA concentration in liver in-creased constantly after injection,and even at 4 h after injection,it maintained a high level [(52.15±18.61) mg·kg-1].Conclu-sion:UA-PL-NP distributes quickly in liver and gastrointestinal tissues on the early stage of injection.After administration,UA concentration in gastrointestinal tissues releases into blood and the redistribution reaches balance.In this way,a high-concentration of UA maintains in liver tissue.UA-PL-NP has a good hepatic targeting distribution characteristic in mice.",
        "keywords": [
            "URSOLIC ACID phospholipids nanostructures pharmacokinetics chromatography",
            "high pressure liquid mice"
        ],
        "authors": [
            {
                "name": "LI Wen",
                "org": " Tianjin Medical University Cancer Institute & Hospital,Tianjin ,China"
            },
            {
                "name": "YAN Zhao",
                "org": " Tianjin Medical University Cancer Institute & Hospital,Tianjin ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": " Tianjin Medical University Cancer Institute & Hospital,Tianjin ,China"
            },
            {
                "name": "MIAO Wei",
                "org": " Tianjin Medical University Cancer Institute & Hospital,Tianjin ,China"
            },
            {
                "name": "ZHAO Guochen",
                "org": " Tianjin Medical University Cancer Institute & Hospital,Tianjin ,China"
            },
            {
                "name": "YI Yimu",
                "org": " Tianjin Medical University Cancer Institute & Hospital,Tianjin ,China"
            }
        ],
        "venue": "Tianjin Medical Journal",
        "year": 2008
    },
    "8Pamuz4o": {
        "id": "8Pamuz4o",
        "title": "Autoimmune hepatitis with lymphadenectasis: a study of 14 cases",
        "abstract": "Objective To analyze the clinical features of patients with lymphadenectasis and to discuss the possible mechanism.Methods One hundred and fourteen cases with autoimmune hepatitis were collected and analyzed retrospectively in Tianjin Medical University General Hospital from Jan,2000 to Jan,2008.Results They were divided into two groups:group A didn't complicated with lymphadenectasis,while group B complicated with lymphadenectasis.Patients of group B were more easily to develop into cirrhosis than those of group A(57/100 vs 12/14,P<0.05).There was statistical significance in leucocytes and platelets of these 2 groups(P<0.05).Conclusion AIH can complicate with lymphadenectasis,which appeare cirrhosis and hypersplenia more easily and it may be with unfavorable prognosis.",
        "keywords": [
            "Cirrhosis",
            "Hypersplenia",
            "Autoimmune hepatitis",
            "Lymphadenectasis"
        ],
        "authors": [
            {
                "name": "GONG Yanxia",
                "org": "Department of Gastroenterology,Tianjin Medical University General Hospital,Tianjin ,China"
            },
            {
                "name": "WANG Bangmao",
                "org": "Department of Gastroenterology,Tianjin Medical University General Hospital,Tianjin ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Gastroenterology,Tianjin Medical University General Hospital,Tianjin ,China"
            },
            {
                "name": "JIANG Kui",
                "org": "Department of Gastroenterology,Tianjin Medical University General Hospital,Tianjin ,China"
            },
            {
                "name": "WANG Tao",
                "org": "Department of Gastroenterology,Tianjin Medical University General Hospital,Tianjin ,China"
            },
            {
                "name": "YU Qingxiang",
                "org": "Department of Gastroenterology,Tianjin Medical University General Hospital,Tianjin ,China"
            },
            {
                "name": "FANG Weili",
                "org": "Department of Gastroenterology,Tianjin Medical University General Hospital,Tianjin ,China"
            }
        ],
        "venue": "Chinese Journal of Gastroenterology and Hepatology",
        "year": 2008
    },
    "vFFDGhuf": {
        "id": "vFFDGhuf",
        "title": "Mallory-Weiss syndrome: a clinical analysis of 78 cases",
        "abstract": "AIM:To investigate the clinical characteristic,gastroscopic manifestation and treatment of Mallory-Weiss syndrome(MWS).METHODS:We retrospectively analyzed the clinical data of 78 MWS patients admitted to hospital from March 2003 to April 2008.RESULTS:MWS was estimated to account for 6.13%of patients with upper gastrointestinal bleeding.Vomiting after alcohol drinking was the main etiology.Under gastroscope,all tears were longitudinal and common in cardia.The manifestation was correlated with the intervals from pathogenesis to gastroscopic examination(P <0.05),but not associated with H pylori infection and patients'age.Eight of 78 cases were treated with endoscopic hemostasis and hemorrhage did not relapse;among the 70 cases with medical treatment,only 1 case was found with recurrence of bleeding,but after treatment with endoscopic hemostasis,the bleeding was stopped.CONCLUSION:Both conservative and endo-scopic treatment have favorable efficacy in stop-ping the bleeding of MWS,and the latter can be performed when the former was of no effect.",
        "keywords": [
            "Gastroscopy",
            "Mallory-weiss syndrome",
            "Treatment"
        ],
        "authors": [
            {
                "name": "Er-Yan Yuan",
                "org": ",Department of Gastroenterology,General Hospital of Tianjin Medical Uni-versity,Tianjin ,China"
            },
            {
                "name": "Jie Zhang",
                "org": ",Department of Gastroenterology,General Hospital of Tianjin Medical Uni-versity,Tianjin ,China"
            },
            {
                "name": "Zong-Shun Lv",
                "org": ",Department of Gastroenterology,General Hospital of Tianjin Medical Uni-versity,Tianjin ,China"
            }
        ],
        "venue": "World Chinese Journal of Digestology",
        "year": 2008
    },
    "qXn58jIZ": {
        "id": "qXn58jIZ",
        "title": "Inhibition of siRNA Targeting MMP-9 on Ivasion and Migration of Human SGC7901 Gastric Adenocarcinoma Cells",
        "abstract": "Objective:To investigate the effect of MMP-9 siRNA on MMP-9 expression of human SGC7901 gastric adenocarcinoma cells and the inhibition effect on SGC7901 cell invasion and migration thereof.Methods:To design and synthesize siRNA targeting MMP-9,then transfect it into SGC7901 gastric adenocarcinoma cells with oligofectamine.The realtime PCR and Western blotting were used to observe the expression of MMP-9 mRNA and the protein.The Matrgel 3D growth experiment and transwell experiment were used to detect the invasion ability of cells.The Matrgel 2D growth experiment and scratch experiment were used to detect the migration ability of SGC7901 cells.Results:Real-time PCR and Western blotting assay indicated that the expressions of MMP-9 mRNA and the protein in SGC7901 cells interfered by MMP-9 siRNA were significantly lower than those of other two groups.The invasion and migration ability of SGC7901 cells were also degraded after siRNA interference of MMP-9 gene.Conclusion:The targeting RNA interference not only degraded the expression of MMP-9 mRNA and protein,but also inhibited the invasion and migration ability of SGC7901 cells.",
        "keywords": [
            "stomach neoplasms adenocarcinoma RNA interference gelatinases neoplasm invasiveness"
        ],
        "authors": [
            {
                "name": "ZHAO Fengjuan",
                "org": " Department of Gastroenterology,General Hospital of Tianjin Medical University,Tianjin ,China"
            },
            {
                "name": "CUI Xiaowei",
                "org": " Department of Gastroenterology,General Hospital of Tianjin Medical University,Tianjin ,China"
            },
            {
                "name": "LIU Jian",
                "org": " Department of Gastroenterology,General Hospital of Tianjin Medical University,Tianjin ,China"
            },
            {
                "name": "SONG Xiaomei",
                "org": " Department of Gastroenterology,General Hospital of Tianjin Medical University,Tianjin ,China"
            },
            {
                "name": "KANG Chunsheng",
                "org": " Department of Gastroenterology,General Hospital of Tianjin Medical University,Tianjin ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": " Department of Gastroenterology,General Hospital of Tianjin Medical University,Tianjin ,China"
            },
            {
                "name": "ZHANG Qingyu",
                "org": " Department of Gastroenterology,General Hospital of Tianjin Medical University,Tianjin ,China"
            }
        ],
        "venue": "Tianjin Medical Journal",
        "year": 2009
    },
    "H3VX7LrV": {
        "id": "H3VX7LrV",
        "title": "Influential factors of the abradability of dental materials",
        "abstract": "Dental prosthetic restorations replace natural teeth with occlusal function for years in vivo, and the process of chewing is the wear of themselves and natural teeth. The abrasion resistance is the important factor when one chooses dental restorative materials. As the complexity of process of chewing and the oral environment, many factors effect abradability. The main influential factors of abrasion resistance are reviewed in this article.",
        "keywords": [
            "abradability",
            "influential factors",
            "dental materials"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Dept. of Prosthodontics, Hospital of Stomatology, Tianjin Medical University, Tianjin , China"
            },
            {
                "name": "LI Chang-yi",
                "org": "Dept. of Prosthodontics, Hospital of Stomatology, Tianjin Medical University, Tianjin , China"
            }
        ],
        "venue": "International Journal of Stomatology",
        "year": 2009
    },
    "FYGp0syj": {
        "id": "FYGp0syj",
        "title": "The study of Survivin in gastrointestinal tumor",
        "abstract": "There is no identified reason for tumor growth,the balance between cell proliferation and apoptosis is correlated with tumor genesis and development. Survivin,a newly discovered member of the inhibitor of apoptosis protein family,is undetectable or found at very low levels in normal differentiated tissues whereas increased expression has been observed in embryonic tissue and most human malignancies; it inhibits the cell apoptosis,thus facilitates the growth of these cells,it also regulates the cell division and plays a central role in tumor formation. Survivin may be a new target for tumor treatment. This article reviewed survivin on its structure,function and gastrointestinal tumor investigation.",
        "keywords": [
            "Survivin",
            "Apoptosis",
            "Tumor"
        ],
        "authors": [
            {
                "name": "YUAN Eryan",
                "org": " Department of Gastroenterology,General Hospital of Tianjin Medical University,Tianjin ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": " Department of Gastroenterology,General Hospital of Tianjin Medical University,Tianjin ,China"
            },
            {
                "name": "LV Zongshun",
                "org": " Department of Gastroenterology,General Hospital of Tianjin Medical University,Tianjin ,China"
            }
        ],
        "venue": "Chinese Journal of Gastroenterology and Hepatology",
        "year": 2009
    },
    "EMiDX3r5": {
        "id": "EMiDX3r5",
        "title": "Influence of loading on friction and wear properties of pure titanium used in dentistry",
        "abstract": "Objective To study the influence of load on friction and wear properties of pure Titanium (Ti). Methods Two-body wear test was done on pure Ti by a MMV-1 vertical universal friction and wear testing machine in 37℃ with artificial saliva as lubricant, using steatite as the grinding material. Test loads were set as 20, 50 and 100 N. Dynamic friction coefficient was recorded, wear surface morphology was observed with electron microscope, debris element analysis was carried out by XRD and quality wear loss was measured by electronic balance. Results As loads increased, the wear loss and friction coefficient of the pure Ti increased. Under 20, 50 and 100 N loads, the dominant wear form was abrasive wear, adhesion wear accompanied with abrasive wear, and adhesion wear respectively. Conclusions The increase of loads enlarges the wear loss of pure Ti and changes its dominant wear form. Serious adhesion wear occurs under high loading conditions and the lifetime of pure Ti would therefore be shortened.",
        "keywords": [
            "Loading",
            "Wear resistance",
            "Friction and wear test"
        ],
        "authors": [
            {
                "name": "HU Xin",
                "org": ".Stomatological Hospital, Tianjin Medical University, Tianjin , China"
            },
            {
                "name": "ZHANG Jie",
                "org": ".Stomatological Hospital, Tianjin Medical University, Tianjin , China"
            },
            {
                "name": "LIANG Chun-yong",
                "org": ".Stomatological Hospital, Tianjin Medical University, Tianjin , China"
            },
            {
                "name": "LIU Ya-lin",
                "org": ".Stomatological Hospital, Tianjin Medical University, Tianjin , China"
            }
        ],
        "venue": "Chinese Journal of Stomatological Research(Electronic Version)",
        "year": 2009
    },
    "tkjoKcqs": {
        "id": "tkjoKcqs",
        "title": "A meta-analysis of extraintestinal manifestations of inflammatory bowel disease in Mainland China",
        "abstract": "A I M:To summarize the extraintestinal manifestations of inflammatory bowel disease (IBD)in Mainland China to facilitate prompt and accurate diagnosis of this disease. METHODS:IBD-related medical literature over the past 30 years was collected by retrospectively searching the Chinese Database of Biology and Medicine(CBM,1979-01/2008-01).The data concerning the extraintestinal manifestations of IBD were recorded,pooled and statistically analyzed. RESULTS:A total of 169 articles were retrieved, in which 14,963 cases of ulcerative colitis and 3,659 cases of Crohn’s disease were reported.Diverse extraintestinal manifestations were found in approximately 15%of ulcerative colitis patients and 31%of Crohn’s disease patients. CONCLUSION:Besides alimentary tract in-volvement,inflammatory bowel disease often involves multiple organs simultaneously.This may lead to misdiagnosis and bring difficulties to the clinical diagnosis of the disease.",
        "keywords": [
            "Extraintestinal manifestations",
            "Inflammatory bowel disease",
            "Crohn’s disease",
            "Ulcerative colitis",
            "Meta-analysis"
        ],
        "authors": [
            {
                "name": "Lian-Peng Zheng",
                "org": ",Department of Gastroenterology,Tianjin Medical University General Hospital,Tianjin , China"
            },
            {
                "name": "Zong-Shun Lv",
                "org": ",Department of Gastroenterology,Tianjin Medical University General Hospital,Tianjin , China"
            },
            {
                "name": "Jie Zhang",
                "org": ",Department of Gastroenterology,Tianjin Medical University General Hospital,Tianjin , China"
            },
            {
                "name": "Xiao-Cang Cao",
                "org": ",Department of Gastroenterology,Tianjin Medical University General Hospital,Tianjin , China"
            },
            {
                "name": "Xu-Lin Wang",
                "org": ",Department of Gastroenterology,Tianjin Medical University General Hospital,Tianjin , China"
            }
        ],
        "venue": "World Chinese Journal of Digestology",
        "year": 2009
    },
    "Uuz7VtZi": {
        "id": "Uuz7VtZi",
        "title": "Inhibitory effect of adenovirus-mediated short hairpin RNA targeting P85 and Akt1 on growth of human gastric adenocarcinoma cell]",
        "abstract": "To construct a short hairpin RNA(shRNA) adenovirus vector targeting P85 and protein kinase B1 (PKB1/Akt1) and study its effects on the growth of SGC-7901 human gastric adenocarcinoma cells.P85 and Akt1 shRNA expression frames were subcloned to pGSadeno adenovirus vector with homologous recombination technology to construct pGSadeno-P85 + Akt1 (rAd5-P + A) vector. After screening and amplification, the recombinant adenovirus vector was digested with PacI and transfected into SGC-7901 cells and then its titer and transfection efficiency were detected with fluorescent microscope. P85 and Akt1 mRNA protein expression was identified with real-time PCR and Western blot. The proliferative activity of tumor cells was evaluated with MTT assay and flow cytometry in vitro. rAd5-HK and rAd5-P + A mediated by adenovirus were injected into the established subcutaneous SGC-7901 gastric adenocarcinoma in nude mice. During the observation period of 21 days, tumor volume was measured every 3 days to further testify the anti-tumor effect of rAd5-P + A on the SGC-7901 gastric adenocarcinoma cells and cell in situ apoptosis was detected with TUNEL assay.The adenovirus vector rAd5-P + A was successfully constructed and it dramatically downregulated P85 and Akt1 mRNA expression in SGC-7901 gastric adenocarcinoma cells. Compared with a control group of SGC-7901 cells and cells transfected with general adenovirus rAd5-HK as control, P85 and Akt1 protein expression 48 h and 72 h after rAd5-P + A transfection was decreased by 57.5% and 63.7%, 67.8% and 75.6% with statistical significance (P = 0.005, P = 0.003). Cell proliferative activity in rAd5-P + A transfected cells was suppressed from the second day (P < 0.001) and the decreased P85 and Akt1 expression was accompanied by 5.9% -7.1% decrease of S phase fraction and 12.1% - 13.7% increase of G0/G1 phase. The tumor volume of rAd5-P + A treated group was smaller than that of the control and rAd5-HK group with statistical significance (F = 9.871, P = 0.025). Moreover, rAd5-P + A could induce cell in situ apoptosis.Adenovirus-mediated targeting P85 and Akt1 shRNA can inhibit the growth of SGC-7901 human gastric adenocarcinoma cells and this may provide a new strategy of combination gene therapy in gastric adenocarcinoma.",
        "keywords": [],
        "authors": [
            {
                "name": "Jing Zhang",
                "org": "Department of Gastroenterology, Tianjin Medical University General Hospital, Tianjin 300052, China."
            },
            {
                "name": "Yan-Chao Fu",
                "org": ""
            },
            {
                "name": "Chun-Sheng Kang",
                "org": ""
            },
            {
                "name": "Qing-Yu Zhang",
                "org": ""
            },
            {
                "name": "Tao Wang",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            }
        ],
        "venue": "Zhonghua nei ke za zhi",
        "year": 2009
    },
    "YX33SivO": {
        "id": "YX33SivO",
        "title": "Eosinophilic gastroenteritis:a clinical study of 24 cases",
        "abstract": "AIM:To investigate the clinical characteristics,diagnosis,therapy and prognosis of eosinophilic gastroenteritis(EG).METHODS:A total of 24 patients diagnosed as EG were studied.The data concerning the medical history,clinical manifestations,laboratory tests,endoscopic test,pathological examination,therapy and follow-up in these patients were analyzed.RESULTS:About 37.5% of EG patients had a history of allergic diseases,and the development of EG was associated with allergy in 25% of patients.The most common clinical presentation in EG patients was abdominal pain(87.5%).Increased peripheral eosinophil count [(4.59 ± 3.69) ×109/L] was noted in 83.3% of EG patients.En-doscopic examination revealed duodenal edema and erosion.Eosinophilic infiltration in the mucosa was confirmed by biopsy.Ascitic fluid was an exudate with eosinophils.Steroid therapy could relieve symptoms and eosinophilia in a week.EG recurrence might occur,but prognosis was good.CONCLUSION:Increased peripheral eosinophil count and allergy history provide a cue to the diagnosis of EG.Increased eosinophil counts in the gastrointestinal mucosa and ascites are key to the diagnosis of EG.Steroid therapy is better than diet therapy for the disease.EG has a good prognosis.",
        "keywords": [
            "Diagnosis",
            "Eosinophilic gastroenteritis",
            "Therapy",
            "Clinical manifestation",
            "Eosinophil"
        ],
        "authors": [
            {
                "name": "Jing Li",
                "org": ",Department of Gastroenterology,Tianjin Medical University General Hospital,Tianjin ,China"
            },
            {
                "name": "Bang-Mao Wang",
                "org": ",Department of Gastroenterology,Tianjin Medical University General Hospital,Tianjin ,China"
            },
            {
                "name": "Jie Zhang",
                "org": ",Department of Gastroenterology,Tianjin Medical University General Hospital,Tianjin ,China"
            },
            {
                "name": "Kui Jiang",
                "org": ",Department of Gastroenterology,Tianjin Medical University General Hospital,Tianjin ,China"
            },
            {
                "name": "Wei-Li Fang",
                "org": ",Department of Gastroenterology,Tianjin Medical University General Hospital,Tianjin ,China"
            },
            {
                "name": "Jing Cheng",
                "org": ",Department of Gastroenterology,Tianjin Medical University General Hospital,Tianjin ,China"
            },
            {
                "name": "Yang Shen",
                "org": ",Department of Gastroenterology,Tianjin Medical University General Hospital,Tianjin ,China"
            },
            {
                "name": "Shuai Su",
                "org": ",Department of Gastroenterology,Tianjin Medical University General Hospital,Tianjin ,China"
            }
        ],
        "venue": "World Chinese Journal of Digestology",
        "year": 2009
    },
    "bj51lF2x": {
        "id": "bj51lF2x",
        "title": "The predictive value of end-stage liver disease model for spontaneous bacterial peritonitis in cirrhotic patients with ascites]",
        "abstract": "Spontaneous bacterial peritonitis (SBP) is a severe complication in cirrhotics with ascites. Early identification of high-risk patients is crucial for prognostic improvement. We aimed to investigate the predictive value of model for end-stage liver disease (MELD) score at admission in predicting incidence rate of SBP in cirrhotic patients with ascites, so as to evaluate its use in early diagnosis and prognosis of this complication.A retrospective study enrolling 254 consecutive patients with cirrhosis and ascites between June 2003 and June 2006 was carried out. The data collected included the age, sex, etiology of liver disease, serum creatinine, total bilirubin, prothrombin time with international normalized ratio and ascitic fluid analysis of the patients. The patients were graded with MELD formula into 4 groups (MELD < or = 9, 10-19, 20-29, MELD > or = 30). The incidence rate of SBP was compared in the 4 groups according to the MELD score. The predictive accuracy in patients with and without SBP was evaluated with receiver operating characteristic (ROC) curve.SBP developed in 65 (26%) patients during hospitalization. The clinical characteristics were similar between the patients with and without SBP. The mean MELD score for patients with SBP was 23 and for those without was 14 (P < 0.01). Patients with 10-19 had an odds ratio of 1.44 (P > 0.05) for SBP, as compared with patients with MELD < or = 9. The frequency of spontaneous bacterial peritonitis was higher in the patients with MELD > or = 20 than those with MELD < or = 19. The incidence rate of SBP with MELD < or = 19, 20-29 and MELD > or = 30 were 12.5%, 52.38%, and 66.67% respectively. Patients with MELD > or = 30 had an odds ratio of 14 (95% CI 5.41-36.20) for SBP, as compared with patients with MELD < or = 19. Patients with 20-29 had an odds ratio of 7.7 (95% CI 4.17-14.20) for SBP, as compared with patients with MELD < or = 19. Area under curve (AUC) of MELD was 0.774 (95% CI 0.689-0.855).The cirrhotic patients with complicating ascites with higher MELD score have a greater risk of SBP. High MELD score might be an useful predictor of SBP in cirrhotic patients with ascites.",
        "keywords": [],
        "authors": [
            {
                "name": "Xin Wang",
                "org": "Department of Gastroenterology, General Hospital, Tianjin Medical University, Tianjin 300052, China."
            },
            {
                "name": "Bang-Mao Wang",
                "org": ""
            },
            {
                "name": "Kui Jiang",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Wei-Li Fang",
                "org": ""
            },
            {
                "name": "Tao Wang",
                "org": ""
            },
            {
                "name": "Xin-Yuan Li",
                "org": ""
            }
        ],
        "venue": "Zhonghua nei ke za zhi",
        "year": 2009
    },
    "DdGbJS8X": {
        "id": "DdGbJS8X",
        "title": "Wear resistance of three kinds of filling materials for posterior teeth versus the dental enamel",
        "abstract": "BACKGROUND:Currently,the test methods and conclusions of studies on wear resistance of AgHg alloys and resins materials for posterior teeth vary a lot,especially the selection of the wearing materials and their matching performance with the dental enamel. OBJECTIVE:To investigate the bio-tribological properties of the normally-used filling materials for posterior teeth and their matching performance with the dental enamel. DESIGN,TIME AND SETTING:A comparative observation was performed in the Oral Biomaterials Laboratory of Tianjin Medical University Affiliated Stomatology Hospital from July to December in 2008. MATERIALS:FiltekTMP60 and FiltekTMZ350 light-cured composite resins were supplied by Minnesota Mining & Manufacturing Company(American corporation);AgHg alloys were provided by Shanghai Dental Materials Factory;steatite ceramics were perchased from Haimen Tianbu High Frequency Ceramic Factory. METHODS:A loading wear test was done under an artificial saliva lubrication environment by MMV-1 vertical universal friction and wear testing machine. The performance of FiltekTMP60,FiltekTMZ350 composite resins and AgHg alloys in wear pairs were tested,with steatite ceramics used as the wearing materials and the natural enamel as the controls. MAIN OUTCOME MEASURES:Volume wear loss,dynamic frictional coefficient and surface electronic morphology. RESULTS:Volume wear loss followed by ascending was AgHg alloys,dental enamel,FiltekTMZ350,FiltekTMP60(P < 0.05) . Volume wear loss of steatite ceramics followed by ascending was FiltekTMP60,FiltekTMZ350,dental enamel,AgHg alloys(P < 0.05) . The volume wear loss of FiltekTMZ350 and its wearing materials was the closest to that of the dental enamel. The main wear mechanism underlying the dental enamel and composite resins was abrasive wear accompanied wtih adhesive wear,and that of AgHg alloys was chiefly abrasive wear. Trend of dynamic frictional coefficient was similar among enamel,P60 and Z350. AgHg alloys had got the highest stable frictional coefficient. CONCLUSION:The frictional characteristics of the dental enamel and composite resins are similar. The Z350 shows the closest wear resistance to the dental enamel and,accordingly,can avoid the excessive wear of human teeth as a filling material.",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Xu Cheng-wen",
                "org": "Tianjin Medical University Affiliated Stomatology Hospital,Tianjin ,China;Bohai Oil Hospital,Tianjin ,China"
            },
            {
                "name": "Li Chang-yi",
                "org": "Tianjin Medical University Affiliated Stomatology Hospital,Tianjin ,China"
            },
            {
                "name": "Zhang Jie",
                "org": "Tianjin Medical University Affiliated Stomatology Hospital,Tianjin ,China"
            },
            {
                "name": "Liang Chun-yong",
                "org": "School of Materials Science and Engineering,Hebei University of Technology,Tianjin ,China"
            },
            {
                "name": "Hu Xin",
                "org": "Tianjin Medical University Affiliated Stomatology Hospital,Tianjin ,China"
            }
        ],
        "venue": "Journal of Clinical Rehabilitative Tissue Engineering Research",
        "year": 2009
    },
    "7ekBhl6P": {
        "id": "7ekBhl6P",
        "title": "Clinic analysis of multiple primary carcinomas in 20 cases with gastrointestinal system.",
        "abstract": "",
        "keywords": [
            "therapy.",
            "diagnosis",
            "multiple primary carcinomas"
        ],
        "authors": [
            {
                "name": "YE Zhen",
                "org": ".Department of Gastroenterology,Tianjin Medcial University General Hospital,Tianjin ,China"
            },
            {
                "name": "WANG Bang-mao",
                "org": ".Department of Gastroenterology,Tianjin Medcial University General Hospital,Tianjin ,China"
            },
            {
                "name": "ZHAO Xing-hui",
                "org": ".Department of Gastroenterology,Tianjin Medcial University General Hospital,Tianjin ,China"
            },
            {
                "name": "JIANG Kui",
                "org": ".Department of Gastroenterology,Tianjin Medcial University General Hospital,Tianjin ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": ".Department of Gastroenterology,Tianjin Medcial University General Hospital,Tianjin ,China"
            },
            {
                "name": "FANG Wei-li",
                "org": ".Department of Gastroenterology,Tianjin Medcial University General Hospital,Tianjin ,China"
            }
        ],
        "venue": "Chinese Journal of Practical Internal Medicine",
        "year": 2009
    },
    "vVUyo8om": {
        "id": "vVUyo8om",
        "title": "Compapative study on friction and abrasive resistance of resin teeth and natural enamel",
        "abstract": "Objective: To test and compare the friction properties and abrasive resistance of natural enamel and resin teeth. Methods: A loading friction and wear test was done by a pin-plate two-body wear device through in vitro simulation of oral environment. Dynamic friction coefficient was recorded, wear surface morphology was observed with electron microscope, and quality wear loss was detected. Results: Similarchanges in the friction coefficients of resin teeth and enamel, the stable friction coefficient of enamel was 0.90~1.00, ENDURATM TEETH was 0.38, BAYER TEETH was 0.47.Volume wear loss followed by ascending wear were dental enamel, ENDURATM TEETH,BAYER TEETH (P<0.05) ,Volume wear loss of steatite ceramics followed by ascending wear were BAYER TEETH,ENDURATM TEETH, enamel (P<0.05) .Resin teeth wear mechanism was mainly abrasive wear, enamel was fatigue wear. Conclusions: Stable friction coefficient of two resin teeth were much lower than that of natural enamel, wear properties were worse than that of enamel, wear resistance of ENDURATM TEETH was better than that of BAYER TEETH.",
        "keywords": [
            "friction and wear test",
            "friction property",
            "enamel",
            "resin teeth",
            "abrasive resistance"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Stomatological Hospital, TianJin Medical University, TianJin ,China"
            },
            {
                "name": "HU Xin",
                "org": "Stomatological Hospital, TianJin Medical University, TianJin ,China"
            },
            {
                "name": "LIANG Chun-yong",
                "org": "Stomatological Hospital, TianJin Medical University, TianJin ,China"
            },
            {
                "name": "LIU Ya-lin",
                "org": "Stomatological Hospital, TianJin Medical University, TianJin ,China"
            }
        ],
        "venue": "Chinese Journal of Geriatric Dentistry",
        "year": 2009
    },
    "TfyTawfe": {
        "id": "TfyTawfe",
        "title": "OMOM capsule endoscopy in diagnosis of unexplained abdominal pain",
        "abstract": "Objective To understand the domestic OMOM capsule endoscopy in patients with chronic abdominal pain of intestinal diseases in the clinical diagnostic value.Methods Feb.2008-Jan.2010,the OMOM capsule endoscopy produced by Chongqing Jinshan Science and Technology Group was used in 67 patients with chronic abdominal pain(named abdominal pain group) and 46 persons without any symptoms(named healthy people group).All the patients with chronic abdominal pain had been examined with repeated gastroscopy and colonoscopy,but were not found the causes for the abdominal pain.Results For small intestinal mucosa in abdominal pain group,the diagnostic positive rate was 68.7%(46/67),significantly higher than that in healthy people group 21.7%(10/46);about 21 cases suffered from non-specific inflammation of the small intestine in the 46 patients with small intestinal lesions in the abdominal pain group,then followed by single or multiple small bowel polyps in 12 cases.Ileum and jejunum single or multiple small ulcers in 11 cases,with the clinical histories,they were diagnosed small bowel Crohn disease.Small intestinal tumor occurred in 6 cases.About 25.7%(17/67) patients in the abdominal pain group showed absolutely normal small intestine whereas 11 cases were intestinal lymphoid hyperplasia.In abdominal pain patients,OMOM capsule transit time in the small intestine(243.9±61.9) min was significantly longer in healthy people group(215.3±52.9) min(P<0.05);capsule probe time through the stomach(42.6± 18.9) min and the time excreted from the body(83.9±27.4) h respectively were longer,compared with healthy people group(40.6±13.4) min and(74.3±19.1) h,but no significant difference existed(both P>0.05).Conclusion Domestic OMOM capsule endoscopy for small intestinal lesions has higher positive rate,and more security without the pain,and it has good clinical value,especially for patients with unexplained chronic abdominal pain.",
        "keywords": [
            "capsule endoscopy",
            "diagnosis",
            "abdominal pain",
            "intestinal disease"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": " Department of Gastroenterology,Tianjin Medical University General Hospital,Tianjin ,China"
            },
            {
                "name": "WANG Bang-mao",
                "org": " Department of Gastroenterology,Tianjin Medical University General Hospital,Tianjin ,China"
            },
            {
                "name": "ZHANG Qing-yu",
                "org": " Department of Gastroenterology,Tianjin Medical University General Hospital,Tianjin ,China"
            },
            {
                "name": "LIN Rui",
                "org": " Department of Gastroenterology,Tianjin Medical University General Hospital,Tianjin ,China"
            },
            {
                "name": "PIAO Mei-yu",
                "org": " Department of Gastroenterology,Tianjin Medical University General Hospital,Tianjin ,China"
            },
            {
                "name": "CHANG Yi-xiang",
                "org": " Department of Gastroenterology,Tianjin Medical University General Hospital,Tianjin ,China"
            }
        ],
        "venue": "Clinical Focus",
        "year": 2010
    },
    "KnRvZ0PU": {
        "id": "KnRvZ0PU",
        "title": "The effect of Akt1 and Akt2 gene transfection on growth of human gastric epithelial cell GES-1",
        "abstract": "Objective To observe the effects of Akt1 and Akt2 genes transfection on the growth of human gastric epithelial GES-1 cells. Methods The plasmids of p-LXSN-Akt1 which contained the whole Akt1 gene sequence(Akt1 group) and p-LXSN-Akt2 which contained the whole Akt2 gene sequence(Akt2 group) were used to transfect human gastric epithelial GES-1 cells with lipofectamine,the GES-1 cells which were transfected by the empty vector p-LXSN were used as the black vector group,and the no transfected ones were used as the control group. Then the positive cell clones were selected with antibiotics G418. The protein expressions of Akt1,Akt2 and Cyclin D1 in the GES-1 cells were measured by Western blotting analysis;MTT method was applied to detect the proliferation activity of GES-1 cells;the effect of Akt1 and Akt2 genes transfection on the cells cycle of the GES-1 cells was tested by flow cytometry(FCM) . Results Cell modes which expressed Akt1 gene(Akt1 group) and which expressed Akt2 gene(Akt2 group) were obtained. Akt1 group: ①The relative expressions of Akt1 protein(0.96 ± 0.05) were respectively 2.03 ± 0.22 times of the black vector group(0.47 ± 0.02) and 1.48 ± 0.19 times of the control group(0.64 ± 0.03) (all P < 0.01) ,the relative expressions of Cyclin D1 protein(0.74 ± 0.01) were respectively 2.57 ± 0.05 times of black vector group(0.29 ± 0.01) and 3.44 ± 0.04 times of the control group(0.22 ± 0.01) (all P < 0.01);②Compared with the black vector group and control group,the absorbance(A490) values in the first 1,2 days were no significant differences,but there were statistically significant differences(all P < 0.01) in the first 3 to 6 days;③Compared with the black vector group and control group,S phase cells were increased by approximately 20.00% and 21.10%,G2 phase cells were reduced by approximately 20.80% and 15.48%(all P < 0.01) . Akt2 group: ①The relative expression of Akt2 protein(0.95 ± 0.01) were 1.53 ± 0.04 times of the black vector group(0.62 ± 0.02) and 1.69 ± 0.01 times of the control group(0.56 ± 0.01) (all P < 0.01) ,compared with the black vector group(0.29 ± 0.01) and the control group(0.22 ± 0.01) ,the relative expression of Cyclin D1 protein(0.31 ± 0.02) was no significant differences;②Compared with the black vector group and the control group,the A490 values of the first 1 to 6 days were no significant differences;③Compared with the black vector group and control group,S phase cells were no significant differences.Conclusion Akt1 gene transfection could increase the proportion of S-phase cells and enhance the proliferation ability of the GES-1 cells,but the effects of Akt2 gene was not obvious.",
        "keywords": [
            "Gastric mucosa",
            "Cyclin D1",
            "Gene transfer techniques"
        ],
        "authors": [
            {
                "name": "XIE Jia-bei",
                "org": ")"
            },
            {
                "name": "ZHANG Qing-yu",
                "org": ")"
            },
            {
                "name": "KANG Chun-sheng",
                "org": ")"
            },
            {
                "name": "HAN Jing",
                "org": ")"
            },
            {
                "name": "WANG Tao",
                "org": ")"
            },
            {
                "name": "ZHANG Jie",
                "org": ")"
            }
        ],
        "venue": "Chinese Medicinal Biotechnology",
        "year": 2010
    },
    "1ou1IbjK": {
        "id": "1ou1IbjK",
        "title": "Relationship between refractory ulcerative colitis and cytomegalovirus infection",
        "abstract": "AIM:To explore the relationship between refractory ulcerative colitis(UC) and cytomegalovirus(CMV)infection. METHODS:Seventy-six patients with inflammatory bowel disease(IBD)diagnosed at Tianjin General Hospital from July 2000 to February 2009 were included in the study.According to the use of corticosteroid or not and therapeutic effect,these patients were divided into two groups:effective group and refractory group. Cytomegalovirus(CMV)infection of the colon was evaluated by immunohistochemistry. RESULTS:Eleven patients,including three males and eight females,were positive for CMV, while sixty-five patients,including forty males and twenty-five females,were negative for CMV.Of CMV-positive patients,nine belonged to the refractory group,and two belonged to the effective group.The percentage of CMV-positive patients was significantly higher in the refractory group than in the effective group(P<0.05).CMV-positive patients often suffered from high fever,cervical lymphadenopathy,and splenomegaly.No significant difference was noted in endoscopic and pathological manifestations in patients between the effective group and refractory group.Despite diverse clinical manifestations,abdominal pain and diarrhea were main ones observed in this study.Two CMV-positive patients underwent colectomy due to the occurrence of complication. CONCLUSION:Refractory inflammatory bowel disease is related to CMV infection.The course of IBD may become more complicated in the presence of CMV infection.It remains to be investigated whether antiviral therapy can improve the sensitivity to corticosteroid therapy in IBD patients with CMV infection.",
        "keywords": [
            "Ulcerative colitis",
            "Antiviral therapy",
            "Cytomegalovirus",
            "Refractory inflammatory bowel disease"
        ],
        "authors": [
            {
                "name": "Tian-Tian Li",
                "org": ",Department of Gastroenterology,Tianjin Medical University General Hospital,Tianjin ,China"
            },
            {
                "name": "Zong-Shun Lv",
                "org": ",Department of Gastroenterology,Tianjin Medical University General Hospital,Tianjin ,China"
            },
            {
                "name": "Bang-Mao Wang",
                "org": ",Department of Gastroenterology,Tianjin Medical University General Hospital,Tianjin ,China"
            },
            {
                "name": "Jie Zhang",
                "org": ",Department of Gastroenterology,Tianjin Medical University General Hospital,Tianjin ,China"
            }
        ],
        "venue": "World Chinese Journal of Digestology",
        "year": 2010
    },
    "5hY17JeE": {
        "id": "5hY17JeE",
        "title": "Advances in studies on Lipinski’s five rules",
        "abstract": "Lipinski’s rule is one of the common rules for drug molecular design and compound screening. This review summarizes the applications of theses rules in oral and non-oral drugs, on where their shortcomings in non-oral drugs and their prospect in oral drugs are pointed out simultaneously for the purpose of its being comprehended correctly and being used efficiently.",
        "keywords": [
            "Lipinski’s rules",
            "oral drug",
            "drug likeness",
            "non-oral drug",
            "drug design"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": " Tianjin Medical University, Tianjin , China"
            },
            {
                "name": "TAN Chu-bing",
                "org": " Tianjin Drug Discovery Center, Tianjin Institude of Pharmaceutical Research, Tianjin , China"
            },
            {
                "name": "XU Wei-ren",
                "org": " Tianjin Drug Discovery Center, Tianjin Institude of Pharmaceutical Research, Tianjin , China"
            }
        ],
        "venue": "Drug Evaluation Research",
        "year": 2011
    },
    "lhokdKBe": {
        "id": "lhokdKBe",
        "title": "Psychological alterations and autonomic nervous dysfunction in patients with irritable bowel syndrome",
        "abstract": "AIM: To examine the psychological alterations and autonomic nervous dysfunction in patients with irritable bowel syndrome (IBS). METHODS: Twenty-three patients with diarrhea-predominant IBS (IBS-D), 22 patients with constipation-predominant IBS (IBS-C), and 30 healthy people were included in the study. Orthostatic testing was used to analyze the shortrange frequency domain of heart rate variability (ratio of low to high frequency power, LF/HF) and to evaluate psychological alterations and autonomic nervous dysfunction in these patients. Psychological symptoms were measured with the SCL-90 scale. RESULTS: Psychological alterations, such as depression, anxiety, phobia, compulsion and hypersensitivity, were more obvious in IBS patients than in controls (depression: 2.61 ± 0.62 vs 1.39 ± 0.44; anxiety: 2.28 ± 0.54 vs 1.41 ± 0.51, both P < 0.05). There were a more significant increase in the LF/HF and a more significant decrease in the high frequency power in IBS-D patients than in IBS-C patients and normal controls (13.00 nu ± 0.70 nu vs 33.34 nu ± 2.40 nu, 42.20 nu ± 1.37 nu; 4.14 ± 0.30 vs 1.93 ± 0.23, 1.33 ± 0.04, all P < 0.05). CONCLUSION: Psychological alterations and autonomic nervous dysfunction were noted in patients with IBS, especially in IBS-D patients.",
        "keywords": [
            "Parasympathetic nervous system",
            "Orthostatic testing",
            "Sympathetic nervous system",
            "Psychological alteration",
            "Heart rate variability",
            "Irritable bowel syndrome"
        ],
        "authors": [
            {
                "name": "Yuan-Yuan Chang",
                "org": ", Department of Gastroenterology, Tianjin Medical University General Hospital, Tianjin , China"
            },
            {
                "name": "Bang-Mao Wang",
                "org": ", Department of Gastroenterology, Tianjin Medical University General Hospital, Tianjin , China"
            },
            {
                "name": "Yu-Ming Wang",
                "org": ", Department of Gastroenterology, Tianjin Medical University General Hospital, Tianjin , China"
            },
            {
                "name": "Jie Zhang",
                "org": ", Department of Gastroenterology, Tianjin Medical University General Hospital, Tianjin , China"
            },
            {
                "name": "Shuai Su",
                "org": ", Department of Gastroenterology, Tianjin Medical University General Hospital, Tianjin , China"
            }
        ],
        "venue": "World Chinese Journal of Digestology",
        "year": 2011
    },
    "vflwmZnn": {
        "id": "vflwmZnn",
        "title": "Effects of Akt1 and Akt2 Gene Transfection on Invasion and Migration of Human Gastric Epithelial Cell GES-1",
        "abstract": "Objective: To observe the effects of protein kinase B1 (Akt1) and Akt2 gene transfection on invasion and migration of human gastric epithelial cell line GES-1. Methods: The plasmid of p-LXSN-Akt1, which contained the whole Akt1 gene sequence, and p-LXSN-Akt2, which contained the whole Akt2 gene sequence, were used to transfect GES-1 cells with lipofectamine. The GES-1 cells, which were transfected by the empty vector p-LXSN, were the black vector, and the no transfected ones were the control. And then the positive cell clones were selected with antibiotics G418. The protein expressions of Akt1, Akt2 and MMP-2 were measured by Western blotting analysis. Transwell assay was used to analyze the invasion and metastasis capability. The expression of F-actin was detected by immunofluorescence. Results: The GES-1 cell models expressed Akt1 gene (Akt1 group) and Akt2 gene (Akt2 group) were obtained. The protein expressions of MMP-2 were significantly increased in Akt1 and Akt2 groups compared with those of the black vector group and control group (P < 0.01). Transwell assay showed that there was a significantly increased cell invasion of GES-1 cells in Akt1 and Akt2 groups (P <0.01). The expression of F-actin was increased correspondingly in Akt1 and Akt2 groups detected by immunofluorescence. Conclusion: Akt1 and Akt2 gene could increase cell invasion and migration, leading to malignant transformation of GES-1 cells.",
        "keywords": [
            "protein-serine-threonine kinases gastric mucosa epithelial cells cell line matrix metalloproteinase 9 actins neoplasm metastasis"
        ],
        "authors": [
            {
                "name": "XIE Jiabei",
                "org": " General Hospital of Tianjin Medical University, Tianjin ,China"
            },
            {
                "name": "ZHANG Qingyu",
                "org": " General Hospital of Tianjin Medical University, Tianjin ,China"
            },
            {
                "name": "KANG Chunsheng",
                "org": " General Hospital of Tianjin Medical University, Tianjin ,China"
            },
            {
                "name": "HAN Jing",
                "org": " General Hospital of Tianjin Medical University, Tianjin ,China"
            },
            {
                "name": "WANG Tao",
                "org": " General Hospital of Tianjin Medical University, Tianjin ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": " General Hospital of Tianjin Medical University, Tianjin ,China"
            }
        ],
        "venue": "Tianjin Medical Journal",
        "year": 2011
    },
    "s2q2qQhc": {
        "id": "s2q2qQhc",
        "title": "Value of capsule endoscopy and double-balloon endoscopy in the diagnosis of small bowel tumors and Crohn’s disease: an analysis of 316 cases",
        "abstract": "AIM: To evaluate the value of capsule endoscopy and double-balloon endoscopy in the diagnosis of small bowel tumors and Crohn’s disease.METHODS: A total of 316 patients who were suspected of having small bowel diseases were collected in this study.Of these patients,178 underwent capsule endoscopy,138 underwent double-balloon endoscopy,and 32 underwent both examinations.The detectable rates and diagnosis rates of small bowel tumors and Crohn’s disease achieved using the two methods were compared.RESULTS: The detectable rate and diagnosis rate of small bowel tumors in patients undergoing capsule endoscopy were 4.5% (8/178) and 1.1% (2/178),respectively.The detectable rate and diagnosis rate of small bowel tumors in patients undergoing double-balloon endoscopy were 18.1% (25/138) and 15.2% (21/138),respectively.There are significant differences in the detectable rate and diagnosis rate of small bowel tumors between patients undergoing capsule endoscopy and those undergoing double balloon endoscopy (both P < 0.01).The detectable rate and diagnosis rate of Crohn’s disease in patients undergoing capsule endoscopy were 3.4% (6/178) and 1.7% (3/178),respectively.The detectable rate and diagnosis rate of Crohn’s disease in patients undergoing double-balloon endoscopy were 15.9% (22/138) and 10.1% (14/138),respectively.There are significant differences in the detectable rate and diagnosis rate of Crohn’s disease between patients undergoing capsule endoscopy and those undergoing double-balloon endoscopy (both P < 0.01).Of 32 patients who underwent both capsule endoscopy and double-balloon endoscopy,5 patients were diagnosed with small bowel tumors by double-balloon endoscopy and confirmed by pathological examination,1 was found with small bowel tumors by capsule endoscopy,and 3 were diagnosed with Crohn’s disease by both capsule endoscopy and double-balloon endoscopy.CONCLUSION: Double balloon endoscopy is superior to capsule endoscopy in the diagnosis of small bowel tumors and Crohn’s disease.Combination of capsule endoscopy and double-balloon endoscopy can improve diagnosis and reduce misdiagnosis of small intestinal diseases.",
        "keywords": [
            "Double-balloon endoscopy",
            "Crohn’s disease",
            "Capsule endoscopy",
            "Small bowel tumors"
        ],
        "authors": [
            {
                "name": "Fei Chen",
                "org": ",Department of Gastroenterology,Tianjin Medical University General Hospital,Tianjin ,China"
            },
            {
                "name": "Jie Zhang",
                "org": ",Department of Gastroenterology,Tianjin Medical University General Hospital,Tianjin ,China"
            },
            {
                "name": "Zhong-Qing Zheng",
                "org": ",Department of Gastroenterology,Tianjin Medical University General Hospital,Tianjin ,China"
            },
            {
                "name": "Bang-Mao Wang",
                "org": ",Department of Gastroenterology,Tianjin Medical University General Hospital,Tianjin ,China"
            },
            {
                "name": "Zong-Shun Lv",
                "org": ",Department of Gastroenterology,Tianjin Medical University General Hospital,Tianjin ,China"
            }
        ],
        "venue": "World Chinese Journal of Digestology",
        "year": 2011
    },
    "HI9uI8dg": {
        "id": "HI9uI8dg",
        "title": "The Study of Relationship between Plasma Chemerin and Inflammation in Patients of Type 2 Diabetes Mellitus with Nonalcoholic Fatty Liver Disease",
        "abstract": "Objective:To investigate the relationship between plasma chemerin and inflammation in patients of type 2 diabetes mellitus(T2DM) with nonalcoholic fatty liver disease(NAFLD).Methods:The plasma levels of chemerin were detected by enzyme-linked immunosorbent asssy(ELISA) in all subjects of group A(T2DM with NAFLD),group B(T2DM without NAFLD) and group C(nomal group).At the same time the levels of blood glucose,blood lipids,glycated hemoglobin(HbA1c),fasting insulin(FINS),visceral adipose tissue,high-sensitivity C-reactive protein(hs-CRP),tumor necrosis factor(TNF)-α and interleukin 6(IL-6) were detected in three groups.The homeostasis model assessment for insulin resistance(HOMA-IR) was calculated and the relationship between plasma chemerin and inflammation was analyzed.Results:The plasma levels of chemerin were(130.87±33.84) μg/L,(115.97±21.82) μg/L and(87.01±9.63) μg/L in group A,group B and group C respectively.The plasma level of chemerin was significantly higher in group A and group B compared with that of control,and which was higher in group A than that of group B(P < 0.01).The plasma chemerin level in T2DM with NAFLD was positively correlated with waist circumference,low density lipoprotein cholesterol(LDL-C),visceral adipose tissue,TNF-α and IL-6.Multiple stepwise regression analysis showed that visceral adipose tissue,TNF-α and IL-6 were independent related factors in influencing the level of plasma chemerin.Conclusion:Chemerin may play an important role in the inflammatory reaction of T2DM with NAFLD.",
        "keywords": [
            "diabetes mellitus",
            "type 2 fatty liver blood glucose lipids insulin resistance adipokines inflammation chemerin"
        ],
        "authors": [
            {
                "name": "JIN Errong",
                "org": " The Third Central Clinical Medical College of Tianjin Medical University,Tianjin ,China"
            },
            {
                "name": "WANG Lu",
                "org": " The Third Central Clinical Medical College of Tianjin Medical University,Tianjin ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": " The Third Central Clinical Medical College of Tianjin Medical University,Tianjin ,China"
            },
            {
                "name": "DI Fusheng",
                "org": " The Third Central Clinical Medical College of Tianjin Medical University,Tianjin ,China"
            },
            {
                "name": "LIU Cong",
                "org": " The Third Central Clinical Medical College of Tianjin Medical University,Tianjin ,China"
            },
            {
                "name": "HONG Yanqing",
                "org": " The Third Central Clinical Medical College of Tianjin Medical University,Tianjin ,China"
            }
        ],
        "venue": "Tianjin Medical Journal",
        "year": 2011
    },
    "pbOl4zXc": {
        "id": "pbOl4zXc",
        "title": "Relationship between Plasma Vaspin and Metabolic Index in Diabetic Patients with Fatty Liver",
        "abstract": "Objective: To investigate the relationship between the serum vaspin and the metabolic index in nonalcoholic fatty liver disease (NAFLD) patients with type2 diabetes mellitus (T2DM). Methods: The level of the serum vaspin was assayed by enzyme-linked immunosorbent assay (ELISA) in patients of T2DM with NAFLD (group A), T2DM without NAFLD(group B)and normal control group(group NC). The energy metabolism indexes were detected by indirect calorimetry. The clinical data were also detected. Results: The level of serum vaspin was significantly increased in group B than that of group A and group NC (P < 0.01). The respiratory quotient (RQ) and oxidation of carbohydrate were significantly lower in group A and group B than that of group NC. Levels of 24 hr urine nitrogen, real resting energy expenditure (REE), REE/body weight and the oxidation of fat were significantly higher in group A and group B than those of group NC (P < 0.05 or P < 0.01), but there was no significant difference between group A and group B (P > 0.05). The level of serum vaspin was positively correlated with body weight, body mass index (BMI), REE and gender; meanwhile, it was negatively correlated with RQ in group A. The level of serum vaspin was positively correlated with BMI, waist-to-hip ratio (WHR), fasting blood glucose (FBG), fasting insulin (FINS), homeostasis model assessment of insulin resistance (HOMA-IR), real REE, real REE/body weight and triacylglycerol (TG), while it was negatively correlated with RQ in group B. The concentration of vaspin, 92.4 μg/L could predict the risk of T2DM with fatty liver. Conclusion: The level of serum vaspin was closely related with the substance and energy metabolism, which could be used to predict the risk of type 2 diabetes mellitus with fatty liver.",
        "keywords": [
            "diabetes mellitus",
            "type 2 fatty liver basal metabolism respiration oxygen consumption Vaspin"
        ],
        "authors": [
            {
                "name": "YU Hongyan",
                "org": " The Third Central Clinical Medical College of Tianjin Medical University, Tianjin , China"
            },
            {
                "name": "DI Fusheng",
                "org": " The Third Central Clinical Medical College of Tianjin Medical University, Tianjin , China"
            },
            {
                "name": "WANG Lu",
                "org": " The Third Central Clinical Medical College of Tianjin Medical University, Tianjin , China"
            },
            {
                "name": "LI Qiang",
                "org": " The Third Central Clinical Medical College of Tianjin Medical University, Tianjin , China"
            },
            {
                "name": "JIA Guoyu",
                "org": " The Third Central Clinical Medical College of Tianjin Medical University, Tianjin , China"
            },
            {
                "name": "ZHANG Jie",
                "org": " The Third Central Clinical Medical College of Tianjin Medical University, Tianjin , China"
            },
            {
                "name": "LI Xuefen",
                "org": " The Third Central Clinical Medical College of Tianjin Medical University, Tianjin , China"
            }
        ],
        "venue": "Tianjin Medical Journal",
        "year": 2012
    },
    "SiY01glM": {
        "id": "SiY01glM",
        "title": "MiR-200a Inhibits the Proliferative and Invasive Ability of Human Gastric Cancer Cell Line in vitro Through β-catenin/TCF-4 Signaling Pathway",
        "abstract": "Objective:To explore the effect of miR-200a on the proliferative and invasive activities of gastric carcinoma cell line SGC7901 through p-catenin/TCF-4 signaling.Methods:miR-200a mimics were synthesized chemically and transfected into human gastric cancer cell line SGC7901 by Lipofectamine 2000.Real-time PCR was subsequently performed to detect the transfection effect. The expression of target protein was detected by immunofluorescence assay and Western blot.pTopFlash/pFopFlash luciferase vectors were used as a measure of P-catenin/TCF complex activity.Finally,scratch test,transwell cell invasion,MTT,and flow cytometry were used to detect the migratory,invasive,and proliferative activity of the tumor cells.Results:The location ofβ-catenin in cells shifted from the nucleus to the cytoplasm when the miR-200a expression increased.At the same time,TCF-4 decreased in the nucleus.The transfection induced a 2.27-fold increase in the luciferase activity of TopFlash luciferase vector,but did not affect the FopFlash luciferase vector.The proliferation rate,as well as migratory and invasive abilities of SGC7901,were obviously decreased when miR-200a expression was upregulated,and the miR-200a mimics led to G_0/G_1-phase entry.Conclusion:Over-expression of miR-200a could suppress the activity of the P-catenin/TCF-4 pathway,consequently inhibiting the proliferation and migratory as well as invasive ability of gastric carcinoma cells.",
        "keywords": [
            "MiRNA-200a",
            "β-catenin/TCF-4",
            "Invasion",
            "Gastric carcinoma"
        ],
        "authors": [
            {
                "name": "Juan SU",
                "org": " Department of Gastroenterology,General Hospital of Tianjin Medical University,Tianjin ,China"
            },
            {
                "name": "Qingyu ZHANG",
                "org": " Department of Gastroenterology,General Hospital of Tianjin Medical University,Tianjin ,China"
            },
            {
                "name": "Chunsheng KANG",
                "org": " Department of Gastroenterology,General Hospital of Tianjin Medical University,Tianjin ,China"
            },
            {
                "name": "Anling ZHANG",
                "org": " Department of Gastroenterology,General Hospital of Tianjin Medical University,Tianjin ,China"
            },
            {
                "name": "Tao WANG",
                "org": " Department of Gastroenterology,General Hospital of Tianjin Medical University,Tianjin ,China"
            },
            {
                "name": "Jie ZHANG",
                "org": " Department of Gastroenterology,General Hospital of Tianjin Medical University,Tianjin ,China"
            }
        ],
        "venue": "Chinese Journal of Clinical Oncology",
        "year": 2012
    },
    "Y4MORl4j": {
        "id": "Y4MORl4j",
        "title": "Advances in study on Nrf2/ARE signal pathway and its relevant drugs",
        "abstract": "Nrf2/antioxidant-response-element(ARE) signal pathway is vital in the regulation of cellular oxidative stress response,and the downstream anti-oxidant proteins and phase Ⅱ detoxification enzyme,which were regulated by Nrf2/ARE pathway,play the important roles in the cellular defense protection.Nrf2/ARE pathway plays a key role in the anti-inflammatory,antitumor,neuroprotective,and anti-apoptotic effects.Drugs targeted on Nrf2 are expected to be used in the treatment of several diseases such as multiple sclerosis,diabetes,neurodegenerative diseases,and tumors;Some new drugs such as dimethyl fumarate and Bardoxolone have advanced into late clinical phase.This paper introduces the relationship between Nrf2/ARE pathway and diseases as well as the development of drugs targeted on it.",
        "keywords": [
            "transcription factor",
            "dimethyl fumarate",
            "Nrf2/ARE pathway",
            "Bardoxolone",
            "anti-oxidation"
        ],
        "authors": [
            {
                "name": "PAN Xiao-fei",
                "org": "Tianjin Institute of Pharmaceutical Research,Tianjin ,China;School of Pharmacy,Tianjin Medical University,Tianjin ,China"
            },
            {
                "name": "TAN Chu-bing",
                "org": "Tianjin Institute of Pharmaceutical Research,Tianjin ,China"
            },
            {
                "name": "SHI Li-li",
                "org": "Tianjin Institute of Pharmaceutical Research,Tianjin ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Tianjin Institute of Pharmaceutical Research,Tianjin ,China;School of Pharmacy,Tianjin Medical University,Tianjin ,China"
            },
            {
                "name": "XU Wei-ren",
                "org": "Tianjin Institute of Pharmaceutical Research,Tianjin ,China"
            },
            {
                "name": "TANG Li-da",
                "org": "Tianjin Institute of Pharmaceutical Research,Tianjin ,China"
            }
        ],
        "venue": "Drug Evaluation Research",
        "year": 2013
    },
    "ssBN6yEt": {
        "id": "ssBN6yEt",
        "title": "Study of ultrasonography manifestations in patients with autoimmune hepatitis",
        "abstract": "Objective To analyze ultrasonography manifestations in patients with autoimmune hepatitis,and to discuss the mechanism.Methods 51 patients with autoimmune hepatitis were collected in Tianjin Medical University Hospital from Jan.2000 to May.2008.Then the ultrasonography manifestations were analyzed.Results Ultrasonography manifestations of autoimmune hepatitis were as follows:(1) the liver: the configuration's asymmetry,density's decrease,hepatocirrhosis,cancer and so on;(2) the gallbladdder: thickening of gallbladder wall and edema of the gallbladder fossa,bilestone and so on;(3) splenomegaly;(4) enlargement of abdominal lymph nodes;⑤ ascites and so on.Conclusion Autoimmune hepatitis can demonstrate several abnormal findings involving the liver,gallbladder,lymph nodes,spleen etc.The enlargement of abdominal lymph node is commom in patients with autoimmune hepatitis.",
        "keywords": [
            "Mechanism",
            "Liver",
            "Lymph node",
            "Autoimmune hepatictis",
            "Ultrasonography"
        ],
        "authors": [
            {
                "name": "GONG Yanxia",
                "org": "Department of Gastroenterology,Tianjin Nankai Hospital,Tianjin "
            },
            {
                "name": "WANG Bangmao",
                "org": "Department of Gastroenterology,Tianjin Medical University General Hospital,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Gastroenterology,Tianjin Medical University General Hospital,China"
            },
            {
                "name": "TANG Yanping",
                "org": "Department of Gastroenterology,Tianjin Nankai Hospital,Tianjin "
            }
        ],
        "venue": "Chinese Journal of Gastroenterology and Hepatology",
        "year": 2013
    },
    "DlXuXq2U": {
        "id": "DlXuXq2U",
        "title": "DEVELOPMENT AND APPLICATION OF CLAY-FREE DRILLING FLUID",
        "abstract": "Aiming at the geologic and drilling features of North Shaan oil/gas field, a kind of clay-free drilling fluid is developed. It is composed by several organic and inorganic materials. Its density is about 1.01-1.05 g/cm~3, the funnel viscosity is about 26-30 seconds and the pH value is about 7-9. The formula of the drilling fluid has been optimized and the performance has been systematically tested. The research results show the drilling fluid has great function of borehole-wall protection and sloughing prevention. It can be easily operated and safely applied. So it fully meets the needs of drilling task in this area. By using this drilling fluid, the wells are easily made regular and the drilling speed can reach 10-18 m/h. Besides that, the bit life can be extended 20%-30% longer and the cost of drilling fluid is reduced than that using the average drilling fluid under the same condition.",
        "keywords": [
            "North Shaan oilfield",
            "sloughing prevention",
            "well drilling",
            "borehole wall protection",
            "clay-free drilling fluid"
        ],
        "authors": [
            {
                "name": "You Yuan",
                "org": "College of Chemistry & Chemical Engineering, Xi'an Shiyou University"
            },
            {
                "name": "Zhang Jie",
                "org": "College of Chemistry & Chemical Engineering, Xi'an Shiyou University"
            },
            {
                "name": "Zhao Xiangyang",
                "org": "College of Chemistry & Chemical Engineering, Xi'an Shiyou University"
            }
        ],
        "venue": "Natural Gas Industry",
        "year": 2006
    },
    "P3Uhtfa1": {
        "id": "P3Uhtfa1",
        "title": "Rheological properties of xanthan gum solution in drilling fluid",
        "abstract": "In this paper, the rheological properties of low-concentration water solution of Xanthan gum are evaluated at different concentrations, different pH values, temperatures and shear rates, and the rheologic model is set up. The results show that at a given shear rate, the higher concentration induces higher viscosity and stronger nonnewtonianism; the higher temperature will bring the lower viscosity, the viscosity will get back to 70%-80% of the original when the temperature returns to the original; the viscosity reaches the highest when pH is kept within 6-7; and when the shear rate is 1-100 s-1 ,the viscosity will decrease very sharply in contrast to slow viscosity decrease when the shear rate is within 100-500 s-1. The rheological model complies with the Herschel-Bulkley Equation, and the system has prominent shear-thinning effects, with indistinctive thixotro-py. In petroleum drilling, the low-concentration (0. 1%-0. 7%, mass fraction) XC solution can meet the needs of viscosity picking-up, filtration reduction, and flow pattern improvement.",
        "keywords": [
            "Concentration",
            "Drilling",
            "Drilling fluid",
            "Rheological properties",
            "Water-soluble glue solution",
            "Xanthan gum"
        ],
        "authors": [
            {
                "name": "ZHAO Xiang-yang",
                "org": "Xi'an Shiyou University(Xi'an Shiyou University ^),Xi An,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Xi'an Shiyou University(Xi'an Shiyou University ^),Xi An,China"
            },
            {
                "name": "Yuan You",
                "org": "Xi'an Shiyou University(Xi'an Shiyou University ^),Xi An,China"
            }
        ],
        "venue": "Natural Gas Industry",
        "year": 2007
    },
    "ZEjIrjZa": {
        "id": "ZEjIrjZa",
        "title": "Electronic Commerce And Guard",
        "abstract": "The electronic commerce product following computer technology and networking development. The electronic commerce is one of Internet application main domains and is the more and more important management pattern. The article introduced the electronic commerce elementary knowledge and the advanced idea, And has analyzed the security technology emphatically in the electronic commerce application.",
        "keywords": [
            "Security",
            "Guard",
            "Electronic commerce"
        ],
        "authors": [
            {
                "name": "ZHU Zhan-li",
                "org": "Xi'an Shiyou University,Xi'an ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Xi'an Shiyou University,Xi'an ,China"
            }
        ],
        "venue": "Computer Knowledge and Technology(Academic Exchange)",
        "year": 2007
    },
    "zZrToaem": {
        "id": "zZrToaem",
        "title": "The XML Security Technology and E-Commerce",
        "abstract": "XML is a data standard and Its structure, interoperability, scalability and easyexchange feature have been widely used in many industries. XML for the realization safe and highly effective E-Commerce provided one kindof open standard. It solved some of the weaknesses of traditional data exchange, and lead small and medium-sized enterprises into E-Commerce. XML Security technology can ensure the integrity, authenticity and non-repudiation of data transmission. It can also make up for the deficiencies of the traditional security technologies. And XML Signature and XML Encryption is the foundation of a series of standard of the secure Web Services. Therefore, Ensure the safety of XML data will play a vital role in the entire Web development.",
        "keywords": [
            "Encryption",
            "XML-Security",
            "E-commerce"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Xi'an Shiyou University Computer College,Xi'an ,China"
            },
            {
                "name": "ZHU Zhan-li",
                "org": "Xi'an Shiyou University Computer College,Xi'an ,China"
            }
        ],
        "venue": "Computer Knowledge and Technology(Academic Exchange)",
        "year": 2007
    },
    "P599cniD": {
        "id": "P599cniD",
        "title": "THE CONDITIONS OF CARBOXYMETHYLATION OF FENUGREEK GUM",
        "abstract": "Using Fenugreek Gum pieces as feed stock,the technological conditions for preparation of carboxymethyl Fenumgreek Gum are optimized,and the optimal reaction conditions are determined by a series of orthogonal trials and single-fact test.The influence of experimental factors on apparent viscosity of Carboxymethylation Fenugreek Gum solution is investigated.The results indicate that the optimal reaction condition is as follow: NaOH concentration is 0.15mol/L,the ratio of NaOH∶sodium chloroacetate is 1 ∶1.25,the alkalization pretreatment time is 45min,the reaction temperature is 50℃ and the reaction time is 4h.The water insoluble substance content is reduced from 35.8% to 7.9% and the apparent viscosity of Carboxymethylated Fenumgreek Gum is evidently enhanced,which can provide guidance for the industrializition of Carboxymethylated Fenumgreek Gum production.",
        "keywords": [
            "carboxymethylation",
            "modification",
            "alkalization",
            "Fenugreek Gum",
            "apparent viscosity"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "College of Chemistry and Chemical Engineering,Xi′an Shiyou University,Xi′an Shaanxi ,China"
            },
            {
                "name": "GAO Fei",
                "org": "College of Chemistry and Chemical Engineering,Xi′an Shiyou University,Xi′an Shaanxi ,China"
            },
            {
                "name": "HU Qi",
                "org": "College of Chemistry and Chemical Engineering,Xi′an Shiyou University,Xi′an Shaanxi ,China"
            }
        ],
        "venue": "Journal of Southwest Petroleum University(Science & Technology Edition)",
        "year": 2008
    },
    "dESkyD2u": {
        "id": "dESkyD2u",
        "title": "STABILITY OF HETEROPOLYGLYCOSIDE WATER BASE DRILLING FLUID",
        "abstract": "Argillaceous rheological property and penetrability of clay have been decided by zeta-potential,which is conducted by the mobile surface of clay particle and electroneutrality media of solution.The change of property of zeta-potential of clay particle is the basis of that of the argillaceous rheological property.Different amount of heteropolyglycoside has been added into 4% bentonite drilling fluid to combine potassium polyacrylate and lignosulfonate respectively to measure the parameters of argillaceous rheological property.In addition,zeta-potential of heteropolyglycoside drilling fluid clay has been measured by electrophoretic method.The results show that the drilling fluid has excellent stability and argillaceous rheological property when the conditions are as follows:2%—6% addition of heteropolyglycoside,combination of 3% SJ and 0.1%—0.5% lignosulfonate or 0.1% potassium polyacrylate.",
        "keywords": [
            "bentonite",
            "lab tset",
            "heteropolyglycoside",
            "stability",
            "zeta-potential",
            "water base drilling fluid"
        ],
        "authors": [
            {
                "name": "HU Qi",
                "org": "Xi'an Shiyou University"
            },
            {
                "name": "ZHANG Jie",
                "org": "Xi'an Shiyou University"
            },
            {
                "name": "GAO Fei",
                "org": "Xi'an Shiyou University"
            }
        ],
        "venue": "Natural Gas Industry",
        "year": 2008
    },
    "9qGjWOdm": {
        "id": "9qGjWOdm",
        "title": "Microwave-assisted Synthesis of [(Bis-carboxymethyl-amino)-methyl]-phenol Compounds",
        "abstract": "[(Bis-carboxymethyl-amino)-methyl]-phenol compounds were synthesized under microwave irradiation.Compared with the conventional synthesis,the reaction time was greatly saved,and the yields were relative high.",
        "keywords": [
            "microwave [(bis-carboxymethyl-amino)-methyl]-phenol Mannich"
        ],
        "authors": [
            {
                "name": "TANG Ying",
                "org": "College of Chemistry and Chemical Engineering,Xi'an ShiYou University,Xi'an,,P.R.China"
            },
            {
                "name": "MA Chao",
                "org": "College of Chemistry and Chemical Engineering,Xi'an ShiYou University,Xi'an,,P.R.China"
            },
            {
                "name": "ZHANG Jie",
                "org": "College of Chemistry and Chemical Engineering,Xi'an ShiYou University,Xi'an,,P.R.China"
            },
            {
                "name": "CHEN Gang",
                "org": "College of Chemistry and Chemical Engineering,Xi'an ShiYou University,Xi'an,,P.R.China"
            }
        ],
        "venue": "Science Technology and Engineering",
        "year": 2009
    },
    "Qa4UaZAE": {
        "id": "Qa4UaZAE",
        "title": "RESEARCH ON H2S ABSORBENT-PCC IN DRILLING FLUID",
        "abstract": "In this study,H2S absorbability of 5 different phenolic compounds in water-base drilling fluid has been tested by experiments.Through the collocation of phenolic compound and carbohydrates,a new-type H2S absorbent-PCC with better absorbability has been developed.Testing result shows 1967.24mg/L H2S will be absorbed when the content of PCC in water-base drilling fluid is 4000mg/L.",
        "keywords": [
            "phenolic compound",
            "carbohydrates",
            "absorbent",
            "H2S",
            "drilling fluid"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "School of Chemistry and Chemical Engineering,Xi'an Shiyou University"
            },
            {
                "name": "LI Shugang",
                "org": "School of Chemistry and Chemical Engineering,Xi'an Shiyou University"
            }
        ],
        "venue": "Natural Gas Exploration and Development",
        "year": 2009
    },
    "zlPe6yTo": {
        "id": "zlPe6yTo",
        "title": "Laboratory research on improved water-based clear fracturing fluid",
        "abstract": "To avoid the defect of current clear fracturing fluid such as poor property at high temperature and high cost of application,an improved water-based clear fracturing fluid is developed,which consist of main agent CTAB,temperature control agent Na2S2O3,clay inhibitor KCl.The performance is tested through laboratory experiments.Results show that the shear and high temperature resistance of the improved clear fracturing fluid are better.It also has high proppant-carrying capacity in the alkali environment blow 85 ℃,when it contacts with diesel oil or crude oil,it can gelout in two hours without residue left.The break raffinate is compatible with the formation water and crud oil.",
        "keywords": [
            "compatibility",
            "temperature stability",
            "improvement",
            "clear fracturing fluid",
            "evaluation"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "The Department of Chemistry and Chemical Engineering,Xi'an Shiyou University,Xi'an ,China"
            },
            {
                "name": "CAO Yi",
                "org": "The Department of Chemistry and Chemical Engineering,Xi'an Shiyou University,Xi'an ,China"
            }
        ],
        "venue": "Oil Drilling & Production Technology",
        "year": 2009
    },
    "61DJyEVa": {
        "id": "61DJyEVa",
        "title": "Compatibility evaluation between polysaccharides and silicate drilling fluids",
        "abstract": "In order to expand the application of silicate drilling fluids, polysaccharides of HV-CMC, XC, and SJ are used to study their compatibility with silicate drilling fluids. The experimental results show their appropriate doses in silicate fluids are 0.3%, 0.1% and 0.6% respectively. HV-CMC and XC are both thickening additives and filtration reducers. While SJ is a thinning additive in addition to a filtration reducer. The different kinds and doses of polysaccharides have little effects on inhibition of silicate drilling fluids. The working temperature limits of HV-CMC, XC and SJ in silicate fluids are 160℃, 120℃ and 80℃ respectively. This study results will provide additional effective additives to regulate the rheology and filtration of silicate drilling fluids in order for reservoir protection.",
        "keywords": [
            "compatibility",
            "reservoir",
            "polysaccharide",
            "silicate drilling fluid",
            "horizontal well",
            "environmental protection"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Xi'an Shiyou University, Xi'an ,China"
            },
            {
                "name": "YANG He-wei",
                "org": "Xi'an Shiyou University, Xi'an ,China"
            }
        ],
        "venue": "Natural Gas Industry",
        "year": 2009
    },
    "XIKb1ACk": {
        "id": "XIKb1ACk",
        "title": "The indoor research of solid free drilling fluids(Ⅰ)",
        "abstract": "The impact of tackifier,fluid loss additive,reservoir protection agents and weighting agents on the fluid viscosity funnel by Marsh funnel.The initial formula of solid free drilling fluid was chosen as:1%～3%tackifier,1%～3%fluid loss additive,1%～3%reservoir protection agents and appropriate dose of weighting agents.In consideration of the influence of viscosity,shear and filtration performance,the result of L_(25)(5~6)orthogonal experiment gave the optimized formula:2%tackifier,2%fluid loss additive,2%reservoir protection agents, appropriate dose of weighting agents.The properties study showed the gel strength was slight, the apparent viscosity was 42.1 mPa·s,yield point was 1.3 Pa,lubrication coefficient was 0.0787,API filtration rate was 5.5 mL and HTHP filtration rate was 14.2 mL.",
        "keywords": [
            "drilling fluids",
            "funnel viscosity",
            "solid free",
            "orthogonal experiment"
        ],
        "authors": [
            {
                "name": "DENG Qiang",
                "org": "College of Chemistry and Chemical Engineering,Xi'an Shiyou University,Xi'an Shanxi, ,China"
            },
            {
                "name": "CHEN Gang",
                "org": "College of Chemistry and Chemical Engineering,Xi'an Shiyou University,Xi'an Shanxi, ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "College of Chemistry and Chemical Engineering,Xi'an Shiyou University,Xi'an Shanxi, ,China"
            },
            {
                "name": "JU Jianfeng",
                "org": "College of Chemistry and Chemical Engineering,Xi'an Shiyou University,Xi'an Shanxi, ,China"
            }
        ],
        "venue": "Petrochemical Industry Application",
        "year": 2010
    },
    "2qNI1Fga": {
        "id": "2qNI1Fga",
        "title": "The indoor research of solid free drilling fluids(Ⅱ)",
        "abstract": "With the optimized formula by orthogonal experiment,the solid free drilling fluids were prepared and screened on temperature resistance,compatibility with oil field water, corrosion,core damage and resistance of the clay's hydration expansion.It was found the drilling fluids can resistant the temperature of 90℃,and it is compatible to the oil field water,its rate of corrosion is less than 0.025 mm/a,and the rate of core damage is less than 30%,it can also resistant the clay's hydration expansion effectively.",
        "keywords": [
            "drilling fluids",
            "funnel viscosity",
            "properties",
            "solid free"
        ],
        "authors": [
            {
                "name": "CHEN Gang",
                "org": "College of Chemistry and Chemical Engineering,Xi'an Shiyou University,Xi'an Shanxi, ,China"
            },
            {
                "name": "DENG Qiang",
                "org": "College of Chemistry and Chemical Engineering,Xi'an Shiyou University,Xi'an Shanxi, ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "College of Chemistry and Chemical Engineering,Xi'an Shiyou University,Xi'an Shanxi, ,China"
            }
        ],
        "venue": "Petrochemical Industry Application",
        "year": 2010
    },
    "RClMhaCC": {
        "id": "RClMhaCC",
        "title": "An evaluation of high-temperature inhibition behavior of heteropolysaccharide drilling fluids",
        "abstract": "The purpose of this study is to improve the high-temperature performance of the inhibitor of the heteropolysaccharide drilling fluid SJ,which is evaluated by drill cuttings recycling recovery rate experiment,linear shale expansion rate experiment,mud ball soaking test,and plotting of curves of rheologic parameters and filtration vs.SJ fluid dose.The study shows when the dose of SJ is added to WBM by 1-6%,the SJ fluid will have good properties like shale inhibition,rheology and filtration,and can work normally at temperatures up to 140℃.The inhibition mechanism of the SJ fluid includes such aspects as continuous semipermeable membrane,filtration reduction by gel-soft grains packing,and silicon locking of shell to avoid hydration,etc.This study recommends a new inhibitor for WBM used to drill through reservoirs without damage.",
        "keywords": [
            "Deep well",
            "Evaluation",
            "Heteropolysaccharide",
            "High temperature",
            "High-temperature inhibition",
            "Reservoir protection",
            "Water-based drilling fluid"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Xi'an Shiyou University(Xi'an Shiyou University ^),Xi An,China"
            },
            {
                "name": "Gang Guo",
                "org": "Xi'an Shiyou University(Xi'an Shiyou University ^),Xi An,China"
            }
        ],
        "venue": "Natural Gas Industry",
        "year": 2010
    },
    "7Nb10QI6": {
        "id": "7Nb10QI6",
        "title": "SYNTHESIS OF ALUMINUM CITRATE AND PREPARATION OF HPAM/AL CITRATE WEAK GEL SYSTEM",
        "abstract": "The effect of the synthesis conditions of aluminum citrate on the viscosity of HPAM/Al citrate weak gel system were investigated,including temperature,reaction time,pH and the mol ratio of citric acid to aluminum chloride,and it was found that the optimal reaction conditions were that the temperature is 80℃,the reaction time is 3h,the pH is 7.0,and the mol ratio of citric acid to aluminum chloride is 1:2.0.The HPAM/Al citrate weak gel was prepared by using oilfield sewage with different methods,and it was found that pre-crosslinked HPAM/Al citrate diluted using oilfield sewage would give the similar weak gel performance to the system prepared using tap water.",
        "keywords": [
            "aluminum citrate",
            "oilfield sewage",
            "viscosity",
            "HPAM/Al citrate weak gel system",
            "synthesis"
        ],
        "authors": [
            {
                "name": "CHEN Gang",
                "org": "College of Chemistry and Chemical Engineering,Xi'an Shiyou University"
            },
            {
                "name": "TANG Ying",
                "org": "College of Chemistry and Chemical Engineering,Xi'an Shiyou University"
            },
            {
                "name": "ZHANG Jie",
                "org": "College of Chemistry and Chemical Engineering,Xi'an Shiyou University"
            },
            {
                "name": "XU Jiaye",
                "org": "College of Chemistry and Chemical Engineering,Xi'an Shiyou University"
            }
        ],
        "venue": "Drilling & Production Technology",
        "year": 2010
    },
    "G7QsIlFk": {
        "id": "G7QsIlFk",
        "title": "Use of differential scanning calorimetry in optimization of crude oil paraffin formulation",
        "abstract": "Based on the advantages of DSC that determined parameters fast, accurately and informatively, this paper analyzed eight different parameters of crude oil wax from Qingxi of Yumen Oil Field and the wax precipitation point, wax content, hydrocarbons and length of carbon chain distribution and degree of branching and other parameters were obtained. With these data, the single-dosage of paraffin remover was prepared and the optimized oil-based paraffin remover composed of calcium petroleum sulfonate, fatty alcohol ethoxylates (JFC), mixed alcohol and so on was found. The diversification of wax thermal characteristics in crude oil by DSC before and after adding the paraffin remover were analyzed. In addition, the wax dissolving rate was determined by the indoor static wax dissolving method, and the results showed that the most effective paraffin removal effect could be up to 0.455 6 h-1 (40 °C), with the addition of 150 mg/L paraffin remover to the crude oil.",
        "keywords": [
            "Calcium petroleum sulfonate",
            "Differential scanning calorimetry",
            "Formular",
            "Mixed alcohol",
            "Optimize",
            "Paraffin rmover",
            "Polyoxyethylene alkyl ether"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Xi'an Shiyou University(Xi'an Shiyou University ^),Xi An,China"
            },
            {
                "name": "Yan Sun",
                "org": "Xi'an Shiyou University(Xi'an Shiyou University ^),Xi An,China"
            },
            {
                "name": "Gang Chen",
                "org": "Xi'an Shiyou University(Xi'an Shiyou University ^),Xi An,China"
            },
            {
                "name": "Zuchao Meng",
                "org": "Xi'an Shiyou University(Xi'an Shiyou University ^),Xi An,China"
            },
            {
                "name": "Naiwang Yang",
                "org": "Xi'an Shiyou University(Xi'an Shiyou University ^),Xi An,China"
            }
        ],
        "venue": "Speciality Petrochemicals",
        "year": 2011
    },
    "QJRLEUUn": {
        "id": "QJRLEUUn",
        "title": "ADVANCES IN STABILITY AND DETERGENCE OF METHANOL-GASOLINE BLENDS",
        "abstract": "The effect of temperature,methanol content,water content and gasoline composition on the stability of the methanol-gasoline blends and the domestic development of blending agents are reviewed.Deposited species in gasoline engine and the effect on its formation are introduced.In addition,the influence of methanol-gasoline blends on the efficiency and function of salable detergents are discussed.Finally,some suggestions are given: the systematic laboratory analysis on blending agents of methanol-gasoline blends is necessary,as well as the feasibility studies of methanol blending with various gasoline,and screening out or researching and finding special detergents for methanol-gasoline blends is also important and necessary.",
        "keywords": [
            "detergence",
            "methanol-gasoline blends",
            "stability",
            "deposits",
            "blending agents"
        ],
        "authors": [
            {
                "name": "Zhang Jie",
                "org": "Xi'an Shiyou University,Xi'an ,Shaanxi,China"
            },
            {
                "name": "Yang Chengcheng",
                "org": "Xi'an Shiyou University,Xi'an ,Shaanxi,China"
            },
            {
                "name": "Tang Ying",
                "org": "Xi'an Shiyou University,Xi'an ,Shaanxi,China"
            }
        ],
        "venue": "Speciality Petrochemicals",
        "year": 2011
    },
    "5849fD7n": {
        "id": "5849fD7n",
        "title": "Study of cross-linking modification for SP tree gum and its application as mud additives",
        "abstract": "To improve the water solubility and viscosity of tree gum(SP) solution,a new material(SP-1) was developed with SP tree gum as main agent and epichlorohydrin as crosslinker.It was analyzed by the means of DSC curves which showed the phase transformation temperature of SP and SP-1 appeared at 159 ℃ and 156.17 ℃ respectively,indicating the decrease of the hydroxyl amount of SP-1 from that of SP.The optimum reaction conditions were determined by the orthogonally designed experiment and the error analysis.The optimal conditions were found as follows,the mass ratio of the crosslinking agent to SP as 56.40 g/100 g,the pH as 10 and the temperature as 50 ℃.The experiment results showed that comparing to SP,SP-1 have better water solubility,with the viscosity enhancing ratio as 116.7% and the filtration reduction ratio as 30%.While in drilling fluids,the viscosity enhancing ratio of SP-1 was 160% and the filtration reduction ratio was 53.2%.When the aging temperature range between 30 ℃ and 120 ℃,the temperature had a slight effect on rheological properties of SP-1 based drilling fluids,and the API reduction kept below 15 mL.The mud ball immersing experiment results show that SP-1 has an excellent inhibitive to hydration and swell of the mud and shale.",
        "keywords": [
            "crosslinking",
            "epichlorohydrin",
            "water base drilling fluids",
            "tree gum",
            "orthogonal experiment"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "College of Chemistry and Chemical Engineering,Xi'an Shiyou University,Xi'an ,China"
            },
            {
                "name": "ZHANG Yunyue",
                "org": "College of Chemistry and Chemical Engineering,Xi'an Shiyou University,Xi'an ,China"
            },
            {
                "name": "CHEN Gang",
                "org": "College of Chemistry and Chemical Engineering,Xi'an Shiyou University,Xi'an ,China"
            }
        ],
        "venue": "Oil Drilling & Production Technology",
        "year": 2011
    },
    "LbtLLdcE": {
        "id": "LbtLLdcE",
        "title": "Preparation and performance evaluation of ammonia-oxidized lignin as drilling fluids additive",
        "abstract": "To further improve temperature resistance and filtration reduction of lignin derivatives in drilling fluids,ammonia-oxidized lignin was prepared with the lignosulphonates.The influences of reaction conditions,such as temperature,pH,and content of oxidizer and ammoniation agent,on the performance of ammonia-oxidized lignin in drilling fluids were investigated.The results showed that the product not only can enhance dynamic sheer force and reduce filtration at room temperature,but also can reduce dynamic sheer force and filtration at high temperature.After aging for 16 hours at 180 ℃,the ammonia-oxidized lignin enhanced the fluid loss reduction rate to 11.4%.Compared with lignosulphonates,the ammonia-oxidized lignin has weaker function of reducing the dynamic sheer force but higher temperature resistance.",
        "keywords": [
            "drilling fluids agent",
            "ammonia-oxidized",
            "lignin",
            "performance evaluation"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "College of Chemistry and Chemical Engineering,Xi’an Shiyou University,Xi’an ,China"
            },
            {
                "name": "YANG Naiwang",
                "org": "College of Chemistry and Chemical Engineering,Xi’an Shiyou University,Xi’an ,China"
            },
            {
                "name": "CHEN Gang",
                "org": "College of Chemistry and Chemical Engineering,Xi’an Shiyou University,Xi’an ,China"
            },
            {
                "name": "SUN Yan",
                "org": "College of Chemistry and Chemical Engineering,Xi’an Shiyou University,Xi’an ,China"
            }
        ],
        "venue": "Oil Drilling & Production Technology",
        "year": 2011
    },
    "d85ARFKE": {
        "id": "d85ARFKE",
        "title": "Synthesis,structure and catalysis study on degradation reaction of PAM of 2-(N,N-biscarboxymethyl)aminomethyl-4-chloro-phenol Cu(Ⅱ)",
        "abstract": "A complex,2-(N,N-biscarboxymethyl)aminomethyl-4-chloro-phenol Cu(Ⅱ),was synthesized using di-sodium 2-(N,N-biscarboxymethyl)aminomethyl-4-chloro-phenol and CuCl2 in water.The crystal structure was characterized by single crystal X-ray diffraction analysis.The result indicates that the copper ion is penta-coordinated.There are two kinds of molecules with different conformation in the crystal,which are fixed by intermolecular hydrogen bonding of carboxyl and phenolic hydroxyl group and form the 1-D supramolecular structure.The result of catalysis study showed that the complex could catalyze the oxidative degradation of PAM by H2O2,and the molar weight can be reduced to 1.66×105 from 6.1×106.",
        "keywords": [
            "PAM",
            "catalysis",
            "single crystal",
            "2-(N",
            "N-biscarboxymethyl)aminomethyl-4-chloro-phenol Cu(Ⅱ)"
        ],
        "authors": [
            {
                "name": "CHEN Gang",
                "org": "College of Chemistry and Chemical Engineering,Xi'an Shiyou University,Xi'an,,China"
            },
            {
                "name": "TANG Ying",
                "org": "College of Chemistry and Chemical Engineering,Xi'an Shiyou University,Xi'an,,China"
            },
            {
                "name": "GU Xue-fan",
                "org": "College of Chemistry and Chemical Engineering,Xi'an Shiyou University,Xi'an,,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "College of Chemistry and Chemical Engineering,Xi'an Shiyou University,Xi'an,,China"
            }
        ],
        "venue": "Chemical Research and Application",
        "year": 2011
    },
    "whWAFaA2": {
        "id": "whWAFaA2",
        "title": "Treatment of oilfield sludge by ammoniated lignin",
        "abstract": "The ammoniated lignin was applied for treatment of oilfield sludge.The treatment performance was evaluated by detecting the calcium content,the loosen degree and water content of the treated oilfield sludge.Results showed that ammoniated lignin presented perfect performance in oilfield sludge treatment;it could reduce the content of replaceable Ca2+ and increase the content of complex calcium in oilfield sludge.Ammoniated lignin could also rise the loosen degree and water content of oilfield sludge significantly.",
        "keywords": [
            "loosen degree",
            "oilfield sludge",
            "ammoniated lignin"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "College of Chemistry and Chemical Engineering,Xi'an Shiyou University,Xi'an Shanxi "
            },
            {
                "name": "SUN Yan",
                "org": "College of Chemistry and Chemical Engineering,Xi'an Shiyou University,Xi'an Shanxi "
            },
            {
                "name": "HUANG Jianli",
                "org": "College of Chemistry and Chemical Engineering,Xi'an Shiyou University,Xi'an Shanxi "
            },
            {
                "name": "CHEN Gang",
                "org": "College of Chemistry and Chemical Engineering,Xi'an Shiyou University,Xi'an Shanxi "
            },
            {
                "name": "QIN Fangling",
                "org": "College of Chemistry and Chemical Engineering,Xi'an Shiyou University,Xi'an Shanxi "
            }
        ],
        "venue": "Environmental Pollution & Control",
        "year": 2011
    },
    "GxKjHpa0": {
        "id": "GxKjHpa0",
        "title": "The orthogonal experiment for optimizing the formulation of a solid-free drilling fluid",
        "abstract": "A series solid-free drilling fluid were prepared by using PAM,KCl,NaCl,CMC, KOH and K -HPAN as treatment agents in this work.The amounts of added treatment reagent were optimized by orthogonal experimental method,and their effects on the properties of obtained drilling fluid were analyzed in detail.It was found from the results that the solid-free drilling fluid with the formulation of KCl:NaCl:PAM:CMC:KPAN:KOH = 3:9: 2:2:2:2 had maximum conductivity,the formulation of KCl:NaCl:PAM:CMC:KPAN: KOH = 3:9:2:2:2:0.5 had best viscosity and the best filtrate reduction was presented in KCl:NaCl:PAM:CMC:KPAN:KOH = 0:3:0:2:2:0.5.",
        "keywords": [
            "solid-free drilling fluid",
            "range analysis",
            "orthogonal experiment"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "College of Chemistry and Chemical Engineering,Xi'an Shiyou University, Xi'an Shanxi ,China"
            },
            {
                "name": "CHEN Gang",
                "org": "College of Chemistry and Chemical Engineering,Xi'an Shiyou University, Xi'an Shanxi ,China"
            }
        ],
        "venue": "Petrochemical Industry Application",
        "year": 2011
    },
    "PETC0Y8o": {
        "id": "PETC0Y8o",
        "title": "Preparation and Properties Screening of Polysaccharide-Lignin as Mud Additives",
        "abstract": "In this paper,a series of lignin Mannich base(LM) was synthesized from lignin(LS),amine and formaldehyde in the first step,and then polysaccharide-lignins(SL) were prepared by the reaction between LM and polysaccharide.The products were characterized by IR,and the properties as mud additives were probed.The results showed that most of the SL could improve the viscosity of the drilling fluid(DF)under room temperature,dilute the DF,and improve the plastic viscosity and the ratio of dynamic shear force value to plastic viscosity after the high temperature treatment at 180℃ for 24 hours.Moreover,most of them could reduce the filtration of the DF.The values of PV,YP,AV and G of the dissoluble SL treated fluid were higher than that of the blank sample,and lower than that of the soluble SL treated fluid.The ratio of dynamic shear force value to plastic viscosity of the dissoluble SL treated fluid increased compared with that of the LS and SJ treated fluid.The dissoluble SL1-2(synthesized from dimethylamine and other materials)could improve the filtration property of the DF obviously,the filtration loss being only 12.7 mL after measured at 180℃ for 24 hours.",
        "keywords": [
            "polysaccharide",
            "drilling fluid additive",
            "reactions",
            "lignin"
        ],
        "authors": [
            {
                "name": "CHEN Gang",
                "org": "College of Chemistry and Chemical Engineering,Xi'an Shiyou University,Xi'an,shannxi ,P R of China"
            },
            {
                "name": "ZHANG Jie",
                "org": "College of Chemistry and Chemical Engineering,Xi'an Shiyou University,Xi'an,shannxi ,P R of China"
            },
            {
                "name": "ZHANG Li",
                "org": "College of Chemistry and Chemical Engineering,Xi'an Shiyou University,Xi'an,shannxi ,P R of China"
            },
            {
                "name": "YANG Nai-Wang",
                "org": "College of Chemistry and Chemical Engineering,Xi'an Shiyou University,Xi'an,shannxi ,P R of China"
            }
        ],
        "venue": "Oilfield Chemistry",
        "year": 2011
    },
    "cn97oSGe": {
        "id": "cn97oSGe",
        "title": "A New Analysis Method for Crude Oil—TGA Method and Its Application",
        "abstract": "A new simple method for rapidly determination the composition of crude oil by thermalgravimetric analysis(TGA) was established.The fractions of crude oil could be determined by analyzing the TGA curve of crude oil sample without considering the chemical nature of various crude oils and their flowability.The results showed that the relative proportions of various compositions in crude oil were in corresponding with its loss-in-weight ratio at different temperature range.Based on it,the optimum carbon number in viscosity reducer could be confirmed and the formulas of paraffin inhibitor and paraffin remover were screened.Furthermore,residue ratio obtained from TGA curve indicated the content of non-oleaginous in the samples,which had great effect on the performance of paraffin inhabitation and removing.And the effect enlarged with increasing content of non-oleaginous in crude oil.",
        "keywords": [
            "paraffin remover",
            "thermalgravimetric analysis curve",
            "composition of crude oil",
            "viscosity reducer",
            "paraffin inhibitor"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "College of Chemistry and Chemical Engineering,Xi'an Shiyou University,Xi'an,Shaanxi ,P R of China"
            },
            {
                "name": "TANG Ying",
                "org": "College of Chemistry and Chemical Engineering,Xi'an Shiyou University,Xi'an,Shaanxi ,P R of China"
            },
            {
                "name": "SUN Wen-Juan",
                "org": "College of Chemistry and Chemical Engineering,Ningxia University,Yinchuan,Ningxia ,P R of China"
            }
        ],
        "venue": "Oilfield Chemistry",
        "year": 2012
    },
    "zgq84097": {
        "id": "zgq84097",
        "title": "EFFECT OF ACETATE ESTER ON THE PHASE STABILITY OF METHANOL-STRAIGHT-RUN GASOLINE BLENDS",
        "abstract": "Effect of a series of acetate ester co-solvents on the phase stability of methanol-straight-run(SR) gasoline blends was studied by testing the phase separate temperature of these blends.Results show that methyl acetate,ethyl acetate,propyl acetate,butyl acetate,amyl acetate and isoamyl acetate all have positive effect on the phase stability of a series of methanol-SR gasoline blends with various blending ratios(M15,M30,M50 and M65) in the temperature range of-27 ℃ to 36 ℃,and this effect enhances with the increase of carbon number in the oxyalkyl of acetate ester.The effect of alkoxy isomerization on the phase stability of methanol-SR gasoline blends was studied by comparing the phase stabilities of these blends containing butyl acetate,amyl acetate and isoamyl acetate respectively.",
        "keywords": [
            "Acetate ester",
            "Methanol straight run gasoline",
            "Phase stability",
            "Solubilizing effect"
        ],
        "authors": [
            {
                "name": "Zhang Jie",
                "org": "School of Chemistry and Chemical Engineering,Xi'an Shiyou University,Xi'an"
            },
            {
                "name": "Yang Chengcheng",
                "org": "School of Chemistry and Chemical Engineering,Xi'an Shiyou University,Xi'an"
            },
            {
                "name": "Chen Gang",
                "org": "School of Chemistry and Chemical Engineering,Xi'an Shiyou University,Xi'an"
            },
            {
                "name": "Tang Ying",
                "org": "School of Chemistry and Chemical Engineering,Xi'an Shiyou University,Xi'an"
            }
        ],
        "venue": "Petroleum Processing and Petrochemicals",
        "year": 2012
    },
    "aoDInGPT": {
        "id": "aoDInGPT",
        "title": "New bactericide derived from Isatin for treating oilfield reinjection water.",
        "abstract": "Isatin, an extract from Strobilanthes cusia (Nees) Kuntze, was the base for synthesizing derivatives that were screened for antibacterial activity against oilfield water-borne bacteria. The bacterial groups are sulfate reducing, iron and total. The derivatives were characterized by spectrums and they showed good to moderate activity against sulfate reducing bacteria.",
        "keywords": [
            "bioinformatics",
            "text mining",
            "biomedical research"
        ],
        "authors": [
            {
                "name": "Gang Chen",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650204, People's Republic of China. haoxj@mail.kib.ac.cn."
            },
            {
                "name": "Hui-Jun Su",
                "org": ""
            },
            {
                "name": "Min Zhang",
                "org": ""
            },
            {
                "name": "Fang Huo",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Xiao-Jiang Hao",
                "org": ""
            },
            {
                "name": "Jing-Rui Zhao",
                "org": ""
            }
        ],
        "venue": "Chemistry Central journal",
        "year": 2012
    },
    "JXBd22EA": {
        "id": "JXBd22EA",
        "title": "Study on Removing Sulphide From Drilling Fluid by Oxidation",
        "abstract": "Desulfuration efficiency of H2O2,K2S2O8 and(NH4)2S2O8 for drilling fluid were studied.Effects of Fe2+,its feeding mode and H2O2 dosage on the desulfuration efficiency of H2O2 were analyzed.The results show that when the Fe2+ and H2O2 are added in turn and the molar ratio of H2O2 to Na2S is 2︰1,the desulfuration efficiency reaches to 55%;The desulfuration efficiencies of K2S2O8 and(NH4)2S2O8 are higher than that of H2O2,and the highest desulfuration efficiency of K2S2O8 is 86%.",
        "keywords": [
            "Drilling fluid",
            "Desulfuration efficiency",
            "Oxidant"
        ],
        "authors": [
            {
                "name": "MENG Xiang-jiao",
                "org": "College of Chemistry and Chemical Engineering,Xi′an Shiyou University,Shannxi Xi′an ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "College of Chemistry and Chemical Engineering,Xi′an Shiyou University,Shannxi Xi′an ,China"
            },
            {
                "name": "CHEN Gang",
                "org": "College of Chemistry and Chemical Engineering,Xi′an Shiyou University,Shannxi Xi′an ,China"
            }
        ],
        "venue": "Contemporary Chemical Industry",
        "year": 2012
    },
    "aDXSmtu8": {
        "id": "aDXSmtu8",
        "title": "STUDY ON THE EFFECT OF n-ALKANOL ON THE PHASE STABILITY OF METHANOL-STRAIGHT-RUN GASOLINE BLENDS",
        "abstract": "Effects of a series of n-alkanol additives on the phase stability of methanol-straight-run gasoline blends were studied by testing phase separate temperature of these blends and analyzing linear regression equation of curves related with n-alkanol amount-phase separate temperature.Results show that the positive effects of C4—C10 n-alkanol on the phase stability of methanol-straight-run gasoline blends are better than that of low carbon number alcohol.Those effects are relative to HLB values of n-alkanol and the volume fraction of methanol(MVF) in the system.The most effective additive to maintain a stable system for M15 and M85 blends(MVF of 15% and 85%,respectively,following the same) is n-hexanol,so does n-decanol for M30,M50 and M65 blends.Under medium MVFs,for blends with same MVF,its phase stability can be improved with the decrease of n-alkanol HLB value;for blends with high MVF or low MVF,there is always an optimum n-alkanol HLB value to maintain a stable system.For systems adding the same n-alkanol,with the increase of MVF in the blends,the phase stability of the system weakens gradually.",
        "keywords": [
            "methanol-straight-run gasoline blends",
            "linear regression",
            "phase stability",
            "HLB value"
        ],
        "authors": [
            {
                "name": "Zhang Jie",
                "org": "School of Chemistry and Chemical Engineering,Xi'an Shiyou University,Xi'an"
            },
            {
                "name": "Yang Chengcheng",
                "org": "School of Chemistry and Chemical Engineering,Xi'an Shiyou University,Xi'an"
            },
            {
                "name": "Tang Ying",
                "org": "School of Chemistry and Chemical Engineering,Xi'an Shiyou University,Xi'an"
            },
            {
                "name": "Chen Gang",
                "org": "School of Chemistry and Chemical Engineering,Xi'an Shiyou University,Xi'an"
            }
        ],
        "venue": "Petroleum Processing and Petrochemicals",
        "year": 2012
    },
    "5r2yj2oU": {
        "id": "5r2yj2oU",
        "title": "THE EFFECT OF n-ALKANOL ON THE PHASE STABILITY OF METHANOL-GASOLINE SYSTEM",
        "abstract": "The experiment on the phase stability was conducted to investigate the effects on the phase stability of methanol-gasoline system when a series of n-alkanol were used as cosolvent.The effects of n-alkanol to the phase separation temperature have been analyzed by using linear regression method. From the results,it can be seen that the n-alkanol of C_3-C_8 had good assistant dissolve effect to methanol-gasoline system of M15(It indicates that the volume fraction of methanol in the methanolgasoline system is 15%),M30,M35,M50,M65 and M85 within the experimental temperature range—25-40℃.Both the structure of n-alkanol and methanol ratio had a significant impact on the phase stability.The codissolve effect was greatly enhanced with the increasing of carbon numbers in the alcohol, and the best codissolve performance was obtained when carbon number was more than five. The relationship between the amount of n-alkanol and phase separation temperature was linear when the ratio of methanol to gasoline is certain.R~2,the curve correlation coefficient,is usually higher than 0.99.The blends phase stability was enhanced with the decrease of HLB value of n-alkanol.",
        "keywords": [
            "methanol-gasoline",
            "linear regression",
            "phase stability",
            "n-alkanol"
        ],
        "authors": [
            {
                "name": "Yang Changchun",
                "org": "School of Chemistry and Chemical Engineering,Xi'an Shiyou University, Xi'an ,Shaanxi,China"
            },
            {
                "name": "Zhang Jie",
                "org": "School of Chemistry and Chemical Engineering,Xi'an Shiyou University, Xi'an ,Shaanxi,China"
            },
            {
                "name": "Tang Ying",
                "org": "School of Chemistry and Chemical Engineering,Xi'an Shiyou University, Xi'an ,Shaanxi,China"
            },
            {
                "name": "Yang Chengcheng",
                "org": "School of Chemistry and Chemical Engineering,Xi'an Shiyou University, Xi'an ,Shaanxi,China"
            }
        ],
        "venue": "Speciality Petrochemicals",
        "year": 2012
    },
    "BOrRc6I7": {
        "id": "BOrRc6I7",
        "title": "Study of influence factors on the measurement of spinning drop interfacial tension",
        "abstract": "The interfacial tension of the crude oil,aromatic,alkanes,cyclohexane with different concentrations of SDBS,SDS were studied by using rotating low interfacial tension tester. Balanced time,speed,working temperature have impact on interfacial tension.The influence of various oil phase to the interfacial tension has also be discussed.The results showed that: The stable interfacial tension can be obtained after 20 min and increase rotation speed beyond the L/D limitation lead to deviation of interfacial tension to a higher value,On contrary, increasing instrument temperature causes the interfacial tension decrease.",
        "keywords": [
            "concentration",
            "surfactant",
            "speed",
            "rotation time",
            "interfacial tension",
            "temperature"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "College of Chemistry and Chemical Engineering,Xi'an Shiyou University, Xi'an Shanxi ,China"
            },
            {
                "name": "YANG Changchun",
                "org": "College of Chemistry and Chemical Engineering,Xi'an Shiyou University, Xi'an Shanxi ,China"
            },
            {
                "name": "TANG Ying",
                "org": "College of Chemistry and Chemical Engineering,Xi'an Shiyou University, Xi'an Shanxi ,China"
            },
            {
                "name": "ZHAO Jingrui",
                "org": "Shaanxi Haian Industrial Co.,Ltd. Xi'an Shanxi ,China"
            }
        ],
        "venue": "Petrochemical Industry Application",
        "year": 2012
    },
    "Sa7m96PD": {
        "id": "Sa7m96PD",
        "title": "PREPARATION OF NITRATION-OXIDATION LIGNOSULFONATE AND THE PERFORMANCE IN DRILLING FLUID",
        "abstract": "Nitration-oxidation lignosulfonate (NOLS) was synthesized with lignosulfonate as raw material, and the synthesis conditions were optimized. The product was characterized by IR and the performance in drilling fluid was evaluated. The results showed that NOLS, prepared under 0-15℃ with 10-15% nitric acid, could improve the viscosity under room temperature, decrease the viscosity under high temperature, reduce the filtration and inhibit the swelling of clay more effectively than lignosulfonate.",
        "keywords": [
            "nitro-oxide lignosulfonate",
            "drilling fluid additive",
            "performance"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "College of Chemistry and Chemical Engineering, Xi'an Shiyou University"
            },
            {
                "name": "CHEN Gang",
                "org": "College of Chemistry and Chemical Engineering, Xi'an Shiyou University"
            },
            {
                "name": "YANG Naiwang",
                "org": "College of Chemistry and Chemical Engineering, Xi'an Shiyou University"
            },
            {
                "name": "ZHANG Li",
                "org": "College of Chemistry and Chemical Engineering, Xi'an Shiyou University"
            },
            {
                "name": "WU Junjie",
                "org": "College of Chemistry and Chemical Engineering, Xi'an Shiyou University"
            }
        ],
        "venue": "Drilling & Production Technology",
        "year": 2012
    },
    "gQ9x3Zid": {
        "id": "gQ9x3Zid",
        "title": "Research progress and clinical vtility of the ischemia-modified albumin",
        "abstract": "The ischemia-modified albumin(IMA) forms after the human serum albumin experiences ischmia/reperfusion,which is a novel marker for myocardial ischemia.IMA exhibits a reduced capacity to bind to certain transition metals,such as cobalt.It can be measured by the Albumin Cobalt Binding test in serum.Several clinical researches suggested that IMA is an ideal biomarker for myocardial ischemia and an important assay for diagnosis of acute coronary syndromes.",
        "keywords": [
            "Myocardial ischemia",
            "Ischemia-modified albumin"
        ],
        "authors": [
            {
                "name": "QIAO Rui",
                "org": "Clinical Laboratory,the Third Hospital of Peking University,Beijing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Clinical Laboratory,the Third Hospital of Peking University,Beijing ,China"
            }
        ],
        "venue": "Journal of Medical Postgraduates",
        "year": 2006
    },
    "v2dxGrIa": {
        "id": "v2dxGrIa",
        "title": "Effects of midazolam on muscarinic receptor of brain in healthy and scopolamine-treated rats]",
        "abstract": "To investigate the recent and permanent effects of pretreatment with midazolam on muscarinic receptor of brain in healthy and scopolamine-treated rats.(1) In recent effect group, thirty-eight male SD rats were randomly divided into 4 groups: control group (Con, n=9), midazolam group (Mid, n=9), scopolamine group (Sco, n=10), midazolam+scopolamine group (Mid+sco, n=10). On the 1st, 2nd, and 3rd days, Mid group and Mid+sco groups were treated with intraperitoneal injection of 50 mg/kg midazolam per day while Con group and Sco group were treated with intraperitoneal injection of the same voluminal physiological saline per day. On the 4th, 5th, and 6th days, Scopolamine 0.8 mg/kg intraperitoneal injection per day was administered in Sco group and Mid+sco group while same voluminal physiological saline was administered in Con group and Mid group. (2) In permanent effect group, thirty-six male SD rats were randomly divided into 4 groups: control group (Con, n=9), midazolam group (Mid, n=9), scopolamine group (Sco, n=9), midazolam+scopolamine group (Mid+sco, n=9). On the 1st, 2nd, and 3rd days, Mid group and Mid+sco group were treated with intraperitoneal injection of 50 mg/kg midazolam per day while Con group and Sco group were treated with intraperitoneal injection of the same voluminal physiological saline per day. On the 10th, 11th, and 12th days, Scopolamine 0.8 mg/kg intraperitoneal injection per day was administered in Sco group and Mid+sco group while the same voluminal physiological saline was administered in Con group and Mid group. (3)Then the rats was decapitated and the cerebra cortex and hippocampus were removed. The binding capacity of muscarinic receptor with [3H] QNB were determined. Bmax and Kd of muscarinic receptor in hippocampus were determined by Scatchard analysis in recent effect group.(1) In recent effect group: the binding capacity of muscarinic receptor in hippocampus was significantly higher in Con group than in Mid group, Sco group and Mid+sco group (P<0.01), which was also higher in Mid group than in Sco group (P<0.05) and Mid+sco group (P<0.01), higher in sco group than in Mid+sco group (P<0.01). Kd of muscarinic receptor in hippocampus in Sco group and Mid group were higher than in Con group and Mid+sco group (P<0.01). Bmax of muscarinic receptor in hippocampus was significantly higher in Con group than in Mid group (P<0.05), Sco group and Mid+sco group (P<0.01), which was also higher in Mid group than in Sco group and Mid+sco group (P<0.01), higher in sco group than in Mid+sco group (P<0.05). There was no significant difference of the binding capacity of muscarinic receptor in cortex. (2) In permanent effect group: the binding capacity of muscarinic receptor in hippocampus was significantly higher in Con group and Mid group than in Sco group and Mid+sco group (P<0.01). There was no significant difference of the binding capacity of muscarinic receptor in cortex.Pretreatment with intraperitoneal injection of 50 mg/kg midazolam for three days had no effect on muscarinic receptor of cortex, but could induce the binding capacity of muscarinic receptor with [3H] QNB and change the density and affinity of muscarinic receptor in hippocampus in healthy and scopolamine-treated rats, yet the changes were not permanent.",
        "keywords": [
            "scopolamine",
            "muscarinic",
            "midazolam",
            "receptor"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Department of Anesthesiology, Peking University First Hospital, Beijing ,China"
            },
            {
                "name": "Xin-min Wu",
                "org": "Department of Anesthesiology, Peking University First Hospital, Beijing ,China"
            },
            {
                "name": "Ping-ping Zuo",
                "org": " Institute of Materia Medica, Chinese Academy of Medical Sciences"
            }
        ],
        "venue": "Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences",
        "year": 2006
    },
    "GVfeX7aa": {
        "id": "GVfeX7aa",
        "title": "Urogenital Mycoplasma Infection and Antibiotic Susceptibility",
        "abstract": "OBJECTIVE To investigate urogenital mycoplasma infection and its drug sensitivity in Beijing from Jul 2002 to Jun 2005. METHODS Mycoplasma were isolated and their antibiotic susceptibility was detected with Mycoplasma IST 2 Reagent Box from France. RESULTS Among 1806 cases 673 cases were with positive mycoplasma,accounting for 37.3% of the total.From them,Ureaplasma urealyticum(Uu) was positive in 541 cases(80.4%),higher than Uu combined with Mycoplasma hominis(Mh) infection(107 cases,15.9%) or Mh alone infection(25 cases,3.7%).The result of drug sensitivity test showed that Uu,Mh and Uu+Mh isolated from both sexes had different drug resistance.The most sensitive and stable antibiotics were josamycin(the rate of sensitivity was 98.7%) and pristinamycin(the rate of sensitivity 92.6%),the next was doxycyline(the rate of sensitivity was 91.8%).It seemed increasing sensitivity trend for tetracycline and erythromycin.The lowest rate of sensitivity was to ofloxacin and ciprofloxacin. CONCLUSIONS It is important to enhance the detection of drug resistance of mycoplasma,guide the drug use and prevent from producing antibiotic resistance.If antibiotic susceptibility testing of mycoplasma can not be tested,josamycin may be selected as the first choice to treat mycoplasma infection.",
        "keywords": [
            "Ureaplasma urealyticum",
            "Drug sensitivity",
            "Antibiotics",
            "Urogenital tract",
            "Mycoplasma hominis"
        ],
        "authors": [
            {
                "name": "YANG Yi",
                "org": "Peking University Third Hospital,Beijing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Peking University Third Hospital,Beijing ,China"
            },
            {
                "name": "ZHANG Xiao-wei",
                "org": "Peking University Third Hospital,Beijing ,China"
            },
            {
                "name": "LIU Zhen-ying",
                "org": "Peking University Third Hospital,Beijing ,China"
            }
        ],
        "venue": "Chinese Journal of Nosocomiology",
        "year": 2006
    },
    "dVE09cJb": {
        "id": "dVE09cJb",
        "title": "Evaluating the level serum NT-proBNP of patients with acute myocardial infarction for cardiac function",
        "abstract": "Objective To get an insight into the serum N-terminal brain natriuretic peptide(NT-proBNP) levels,cardiac functions and left ventricular reconstruction of patients with acute myocardial infarction(AMI) with no severe complications who perform early rehabilitation exercises.Methods 54 cases of AMI patients with no severe complications were divided into 2 groups,with 29 in exercises group(exercises plus medication)and 25 in control group(medication only).Electrochemiluminescence was adopted to detect the NT-proBNP level at the 3rd day following AMI,with echocardiography performed to assess the heart structurally and functionally.Both tests were repeated after 3rd month to evaluate the changes dynamically.Results Results(1)It was found that in the exercises group,the level of NT-proBNP decreased significantly from 1076.00(666.50-1723.50) ng/L at the 3rd day to 211.00(141.75-374.00) ng/L 3rd month after onset(P<0.05),whereas it decreased from 573.00(231.00-1059.50) ng/L to 462.10(218.30-1042.00) ng/L in the control group,with no significant changes.At the end of the 3rd month,significant difference was seen between the two groups(P<0.01).(2)The left ventricular end-diastolic diameter(LVDd) of patients in exercises group increased from(50.63±4.89)mm of the 3rd day to(50.78±4.10)mm 3rd month after AMI onset,with no obvious changes,but significant augment from(50.31±4.27)mm to(51.85±4.37)mm was observed in the control group.There was significant difference in LVDd between both groups(P<0.01) 3rd month later.(3)In the exercises group,LVEF increased significantly from(55±9)% to(60±8)%(P<0.05),while in the control group there was no significant change in left ventricular emission blood fraction(LVEF),which reduced from(53±9)% to(52±8)%.After 3rd month,significant difference was observed in LVEF between the two groups(P<0.05).Conclusion Rehabilitation exercises of AMI patients with no severe complications in the early stages of the disease contribute to reducing the level of serum NT-proBNP,increasing LVEF and possibly decreasing left ventricular reconstruction at the same time with recorded safety and feasibility.",
        "keywords": [
            "N-terminal brain natriuretic peptide(NT-proBNP)",
            "exercises group",
            "left ventricular end-diastolic diameter(LVDd)",
            "left ventricular emission blood fraction(LVEF)"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Department of Laboratory Medicine,Peking University Third Hospital,Beijing ,China"
            },
            {
                "name": "HU Xiao-zhou",
                "org": "Department of Laboratory Medicine,Peking University Third Hospital,Beijing ,China"
            },
            {
                "name": "LI Zhen-rong",
                "org": "Department of Laboratory Medicine,Peking University Third Hospital,Beijing ,China"
            }
        ],
        "venue": "Chinese Journal of Laboratory Diagnosis",
        "year": 2006
    },
    "fA5OfzNf": {
        "id": "fA5OfzNf",
        "title": "Understandings in writing the textbook of laboratory diagnostics",
        "abstract": "This article reviewed the contents of laboratory diagnostics part of Diagnostics(version 1～6)written under the supervise of the Ministry of Health,introduced the features of these five versions and stated the factors that should be considered when writing this textbook: ①Focus on \"3-basis \"culture.②Reflect the new advance of the branch field.③Improve bilingual teaching.④Complete the contents and the composing form.⑤Textbook writing should emphasize on different specialty students.",
        "keywords": [
            "Textbook",
            "Analysis",
            "Laboratory diagnostics",
            "Development"
        ],
        "authors": [
            {
                "name": "WANG Xiao-lin",
                "org": ".Department of Clinical Laboratory,The Third Hospital,Peking University,Beijing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": ".Department of Clinical Laboratory,The Third Hospital,Peking University,Beijing ,China"
            }
        ],
        "venue": "Chinese Journal of Medical Education",
        "year": 2006
    },
    "DwiBRL3i": {
        "id": "DwiBRL3i",
        "title": "The predictive value for serum levels of N-terminal pro-brain natriuretic peptide and high sensitivity C-reactive protein in left ventricular remodeling after acute myocardial infarction",
        "abstract": "Objectives This study was designed to observe the correlation of the levels of serum N-terminal pro-brain natriuretic peptide(NT-proBNP) and high sensitivity C-reactive protein(hs-CRP) between the 3rd day after acute myocardial infarction(AMI) and after 3 months of left ventricular remodeling(LV remodeling) and to establish the predictive levels of NT-proBNP,hs-CRP for LV remodeling after AMI.Methods The blood samples from 106 patients with the first AMI and echocardiography were examined on the 3rd day and after 3 month.LV remodeling was estimated by the changes of left ventricular end-diastolic volume(LVEDV) during the 3rd day and after 3 month.Based on the change of LV remodeling,the 106 patients were divided into two groups:LV remodeling group(defined as the change rate of LVEDV more than 20%) and non-LV remodeling group.Results The correlation coefficients of the change of LVEDV were 0.706 for serum NT-pro BNP and 0.596 for hs-CRP.With a cutoff value of 0.20,the area under the ROC curve(AUCs) was(0.892) for NT-proBNP and 0.825 for hs-CRP.There was no statistically difference between NT-proBNP and hs-CRP.The ROC plot indicated that NT-proBNP was superior to hs-CRP for predicting LV remodeling.Conclusion The level of serum NT-proBNP appropriately reflects LV remodeling after AMI and shows more efficacious than the level of serum hs-CRP.The level of serum NT-proBNP on the 3rd day after AMI and LV remodeling were positively correlated with the level after 3 months.",
        "keywords": [
            "N-terminal pro-brain natriuretic peptide(NT-proBNP)",
            "left ventricular remodeling(LV remodeling)",
            "ROC curve",
            "high sensitivity C-reactive protein(hs-CRP)",
            "acute myocardial infarction(AMI)"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Department of Laboratory Medicine,The Third Hospital,Peking University,Beijing, China"
            },
            {
                "name": "JIA keke",
                "org": "Department of Laboratory Medicine,The Third Hospital,Peking University,Beijing, China"
            },
            {
                "name": "HU xiaozhou",
                "org": "Department of Laboratory Medicine,The Third Hospital,Peking University,Beijing, China"
            },
            {
                "name": "CUI liyan",
                "org": "Department of Laboratory Medicine,The Third Hospital,Peking University,Beijing, China"
            }
        ],
        "venue": "Chinese Journal of Clinical Laboratory Science",
        "year": 2006
    },
    "9MwyKlns": {
        "id": "9MwyKlns",
        "title": "The Predictive Value of Serum Level of N-Terminal Pro-Brain Natriuretic Peptide in Heart Function after Acute Myocardial Infarction",
        "abstract": "Objective: To observe the correlation between the levels of serum N-terminal pro-brain natriuretic peptide (NT-proBNP) on the 3rd day after acute myocardial infarction(AMI) and left ventricular remodeling to evaluate the predictive levels of NT-proBNP for left ventricular remodeling after AMI.Method: In 106 patients with first MI were examined after three days and 3 months with blood samples and echocardiography.Left ventricular remodeling is estimated by the change of left ventricular end-diastolic volume (LVEDV) between the 3rd day and 3 months. Based on the change of LVEDV, the 106 patients were divided into two groups: left ventricular remodeling group and non-left ventricular remodeling group.Results: The correlation coefficients with the change of LVEDV were 0.702 for serum NT-pro BNP. With a cutoff value of 0.20, the area under the ROC curve (AUCs) was 0.892.Conclusion: The levels of serum of NT-proBNP appropriately reflects heart function after AMI.",
        "keywords": [
            "N-terminal pro-brain natriuretic peptide(NT-proBNP)",
            "ROC curve",
            "Echocardiography",
            "Acute myocardial infarction (AMI)",
            "Left ventricular remodeling(LV remodeling)"
        ],
        "authors": [
            {
                "name": "Hu Xiaozhou",
                "org": " Department of Clinical Laboratory Medicine,The Third Hospital of Peking University,Beijing "
            },
            {
                "name": "Zhang Jie",
                "org": " Department of Clinical Laboratory Medicine,The Third Hospital of Peking University,Beijing "
            },
            {
                "name": "Cui Liyan",
                "org": " Department of Clinical Laboratory Medicine,The Third Hospital of Peking University,Beijing "
            }
        ],
        "venue": "Chinese Journal of Microcirculation",
        "year": 2006
    },
    "8Y8CHmAo": {
        "id": "8Y8CHmAo",
        "title": "Initial Investigation of the Level of Total Plasma Homocysteine in 7 Kinds of Tumor",
        "abstract": "Objective Homocysteine,a highly reactive sulfur-containing amino acid,as an intermediary product of methionine metabolism.Some studys showed that the level of homocysteine is higher in several tumors,so its aim is to evaluate the concentration of homocysteine in more kinds of tumor.Methods Homocysteine,folate and vitaminB_(12) status of patients suffering with cancer(includeing colorectal cancer,liver cancer,breast cancer,bladder cancer,kidney cancer,gastric cancer and esophageal cancer) was separately compared with that of normal control group,Results Mean homocysteine level in colorectal cancer,liver cancer,breast cancer,bladder cancer,kidney cancer,gastric cancer and esophageal cancer was significantly higher than that in healthy control group(P<0.05).Mean foalte level in colorectal cancer,liver cancer,breast cancer,bladder cancer,kidney cancer,gastric cancer and esophageal cancer was significantly lower than that in healthy control group(P<0.05).There were no statistically significant differences between groups in vitamin B_(12) level.Conclusion The increase of homocysteine in tumors may be universality.",
        "keywords": [
            "cancer",
            "homocysteine"
        ],
        "authors": [
            {
                "name": "QIAO Rui",
                "org": "Department of Laboratory Medicine,Third Hospital of peking University,Beijing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Laboratory Medicine,Third Hospital of peking University,Beijing ,China"
            },
            {
                "name": "WANG Zheng-hui",
                "org": "Department of Laboratory Medicine,Third Hospital of peking University,Beijing ,China"
            },
            {
                "name": "LIANG Guo-cheng",
                "org": "Department of Laboratory Medicine,Third Hospital of peking University,Beijing ,China"
            },
            {
                "name": "Wu Yong-hua",
                "org": "Department of Laboratory Medicine,Third Hospital of peking University,Beijing ,China"
            }
        ],
        "venue": "Journal of Modern Laboratory Medicine",
        "year": 2006
    },
    "T43CB6wg": {
        "id": "T43CB6wg",
        "title": "The level of total plasma homocysteine in type 2 diabetes patients with and without diabetic nephropathy",
        "abstract": "Objective The aim of this study is to explore the distribution and determinants of plasma total homocysteine(tHcy) concentrations in type 2 diabetes patients with and without diabetic nephropathy,and to assess the relationship between high tHcy and diabetic nephropathy.Methods We studied 242 type 2 diabetes patients including 34 with macroalbuminuria(group1),60 with microalbuminuria(group2),148 with normal microalbuminuria(group3),and 140 with normal glucose tolerance served as normal controls(group4).Basic material are investigated,and Fasting blood and Urine samples are collected for measurement.Creatinine clearance(Ccr) is estimated by Cockcroft-Gault formula and insulin resistance is calculated by the homeostasis model assessment(HOMA).Results The level of tHcy in group1,group2 and group3 are significantly higher than that in group4(16.9±5.0 μmol/L,13.4±3.7 μmol/L,11.8±4.2 μmol/L vs 11.0±6.0 μmol/L,P<0.001).The same consequence is also found for the prevalence of hyperhomocysteinemia(HHe) in four groups(group1:58.8%,group2:36.4%,group3:15.5%,vs group4:7.9%,P<0.001).There is a significant decreasing trend of serum folate and VitB_(12)from group4 to group1(P<0.001).In patients with type 2 diabetes(group1,2,3,n=242),using multivariate linear regression,the age,folate,VitB_(12) and Scr are independent predictors of lg tHcy(R=0.613,R~2=0.376).The risk factors for diabetic nephropathy are evaluated by binary logistic regression.The increment of tHcy(per 5.0 μmol/L tHcy) resulted in a markedly elevated risk for diabetic nephropathy(OR:2.041,95% CI:1.377-3.024) in type 2 diabetes patients.Conclusion Compared with normal controls,the level of tHcy and the prevalence of HHe significantly increase in type 2 diabetes with normal microalbuminuria,and have a considerably increasing trend with the development of diabetic nephropathy.The increased plasma tHcy is one of the risk factors for diabetic nephropathy in type 2 diabetes.The level of plasma tHcy should be monitored in type 2 diabetes patients with and without diabetic nephropathy",
        "keywords": [
            "diabetic nephropathy",
            "homocysteine"
        ],
        "authors": [
            {
                "name": "LIANG Guo-wei",
                "org": "The Department of Laboratory Medicine,Peking University Third Hospital,Beijing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "The Department of Laboratory Medicine,Peking University Third Hospital,Beijing ,China"
            }
        ],
        "venue": "Chinese Journal of Laboratory Diagnosis",
        "year": 2006
    },
    "3c8hgfVl": {
        "id": "3c8hgfVl",
        "title": "Clinical evaluation of methods for detection of Treponema pallidum infection",
        "abstract": "Objective To investigate the application value of four methods for detecting Treponema pallidum infection. Methods Three methods were used to test the serum of 602 cases. Sixty one of these cases were diagnosed as syphilis. The three methods were enzyme linked immunosorbent assay (ELISA), Treponema pallidum particle assay (TPPA) and rapid plasma regain test(RPR). 134 positive samples detected by RPR were re-examined by Fluorescence quantitative PCR(FQ-PCR) method. Results There was no obvious difference between ELISA and TPPA test results(P﹥0.05). The sensibility detected by ELISA and TPPA were 95.1% and 97.8%, while the specificity was 91.8% and 96.9%. There was significant difference between RPR and ELISA or TPPA (P﹤0.05). But those cases detected by FQ-PCR were negative. Conclusions Both ELISA and TPPA methods are good methods for determination of Treponema pallidum infection. The positive rate of FQ-PCR is low in the detection of Treponema pallidum.",
        "keywords": [
            "Treponema pallidum Rapid plasma reagin test(RPR) Enzyme linked immunosorbent assay(ELISA) Treponema pallidum particle assay(TPPA) Fluorescence quantitative PCR"
        ],
        "authors": [
            {
                "name": "LI Zhen-rong",
                "org": "Department of Laboratory Medicine, Peking University Third Hospital, Beijing "
            },
            {
                "name": "LIU Di",
                "org": "Department of Laboratory Medicine, Peking University Third Hospital, Beijing "
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Laboratory Medicine, Peking University Third Hospital, Beijing "
            }
        ],
        "venue": "Beijing Medical Journal",
        "year": 2007
    },
    "u7nU604t": {
        "id": "u7nU604t",
        "title": "Ischemia-modified albumin and C reactive protein in diagnosis of acute coronary syndromes",
        "abstract": "Objective To investigate the values of ischemia-modified albumin(IMA) and C reactive protein (CRP) in early diagnosis of acute coronary syndromes(ACS). Methods Levels of IMA and CRP were detected in 113 patients with ACS or stable angina pectoris (SA) right after admission as were in 76 healthy controls. Receiver operator characteristic curve (ROC curve) analysis was used to determine the optimal cutoff of identifying ACS from SA. Results There were statistical differences in IMA and CRP levels between the patients with ACS and those with SA or the controls. The area beneath the ROC curve of IMA was 0.948. Sensitivity and specificity of IMA at a cutoff value of 70.5 U/mL were 94.4% and 82.6%. Positive predictive value of IMA for ischemia origin was 95.5% and negative was 79.2%. The area beneath the curves of CRP was 0.746. Sensitivity and specificity of CRP at a cutoff value of 4.905 mg/L were 55.6% and 87.0%. Positive predictive value of CRP for ACS was 78.1% and negative was 18.4%. Conclusions Early diagnosis of acute myocardial ischemia can be made by detection of IMA. IMA can significantly enhance the diagnostic sensitivity of ACS.",
        "keywords": [
            "Coronary disease C-reactive protein Ischemia-modified albumins"
        ],
        "authors": [
            {
                "name": "CUI Li-yan",
                "org": ". Department of Laboratory Medicine,Peking University Third Hospital, Beijing , China Corresponding author:ZHANG Jie E-mail:bjmuzhangjie@tom.com"
            },
            {
                "name": "LIU Di",
                "org": ". Department of Laboratory Medicine,Peking University Third Hospital, Beijing , China Corresponding author:ZHANG Jie E-mail:bjmuzhangjie@tom.com"
            },
            {
                "name": "WU Yong-hua",
                "org": ". Department of Laboratory Medicine,Peking University Third Hospital, Beijing , China Corresponding author:ZHANG Jie E-mail:bjmuzhangjie@tom.com"
            },
            {
                "name": "ZHANG Jie",
                "org": ". Department of Laboratory Medicine,Peking University Third Hospital, Beijing , China Corresponding author:ZHANG Jie E-mail:bjmuzhangjie@tom.com"
            }
        ],
        "venue": "The Journal of Practical Medicine",
        "year": 2007
    },
    "gkrJlWri": {
        "id": "gkrJlWri",
        "title": "Relationship between Serum High Sensitivity C-Reative Protein and Atherosclerosis in Patients with Diabetes Mellitus",
        "abstract": "Objective:To explore the role of high sensitivity C-reative protein(hs-CRP) in atherosclerosis in patients with type 2 diabetes mellitus.Methods:141 patients with type 2 diabetes mellitus were divided into 3 groups according to aggregation of cardiovascular major risk factors.The thickness of carotid intima-media was measured and the percentage of plaque was calculated to reflect the extent of atherosclerosis.Levels of serum hs-CRP,lipids,insulin,glucose,blood pressure,bodymass index(BMI) were measured.Result:The more risk factors the more higher levels of BMI,triacylglycerol(TG),HOMA-Insulin Resistance(HOMA-IR),hs-CRP.The mean carotid intima-media thickness(IMT) were 0.68 mm,0.82 mm,0.97 mm and the percentage of plaque were 12.5%,24.1%,42.9% in the groups with the increased number of risk factors respectively.The carotid IMT was significantly different between the groups,but the precents of plaque was not different between the groups.The carotid IMT had positive relation with shrink blood press(SBP),HOMA-IR,hs-CRP.hs-CRP had positive relation with carotid IMT,HOMA-IR,TG and BMI.hs-CRP and HOMA-IR were the independently factors induced the atherosclerosis.Conclusion:There is a close relationship between level of hsCRP with HOMA-IR,IMT,hs-CRP can be as risk factor of atherosclerosis in patients with T2DM.",
        "keywords": [
            "Diabetes mellitus",
            "C-Reactive protein/analysis",
            "Arteriosclerosis/diagnosis",
            "type Ⅱ/complications"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Deparment of Lab.The Third Hospital of Peking University,Beijing "
            },
            {
                "name": "LIU Di",
                "org": "Deparment of Lab.The Third Hospital of Peking University,Beijing "
            },
            {
                "name": "HU Xiao-zhou",
                "org": "Deparment of Lab.The Third Hospital of Peking University,Beijing "
            }
        ],
        "venue": "Chinese Journal of Misdiagnostics",
        "year": 2007
    },
    "5xs3RMtc": {
        "id": "5xs3RMtc",
        "title": "Clinical and molecular biological features of 2 Chinese patients with Kennedy's disease diagnosed by gene analysis",
        "abstract": "Objective: To diagnose Kennedy's disease (KD) via molecular analysis of the androgen receptor gene with suspected KD. Methods: Two patients with suspected KD were reported. We analyzed their clinical features and investigated the number of CAG repeats in the androgen receptor genes. Results: Both of the patients were characterized by slow progression of predominant proximal and bulbar muscle weakness. Patient 2 had oligospermatism. Serum creatine kinase and triglyceride levels were found markedly increased. The exact number of CAG was 52 in patient 1 and 48 in patient 2, respectively. These 2 patients were finally diagnosed as Kennedy's disease through the analysis of androgen receptor gene by PCR and direct sequencing. Conclusions: The method of molecular analysis for KD had been copied in China. The clinical and molecular biological features of 2 Chinese patients with KD had been discussed. KD is a neurodegenerative disorder by proximal limb muscular atrophy and weakness with lower motor neuron signs, bulbar involvement. Dyscrinism and metabolic abnormalities may also be observed. Gene analysis is the unique and reliable methods to diagnose KD.",
        "keywords": [
            "Muscular atrophy",
            " spinal",
            "Receptor",
            " androgen",
            "Repetitive sequences"
        ],
        "authors": [
            {
                "name": "Ming Lü",
                "org": "Peking University(Peking University),Beijing,China"
            },
            {
                "name": "FAN Dong-sheng",
                "org": "Peking University(Peking University),Beijing,China"
            },
            {
                "name": "LI Xiao-ying",
                "org": "Peking University(Peking University),Beijing,China"
            },
            {
                "name": "LIANG Guo-wei",
                "org": "Peking University(Peking University),Beijing,China"
            },
            {
                "name": "Ying Li",
                "org": "Peking University(Peking University),Beijing,China"
            },
            {
                "name": "ZHANG Hua-gang",
                "org": "Peking University(Peking University),Beijing,China"
            },
            {
                "name": "KANG De-xuan",
                "org": "Peking University(Peking University),Beijing,China"
            },
            {
                "name": "Jun Zhang",
                "org": "Peking University(Peking University),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Peking University(Peking University),Beijing,China"
            },
            {
                "name": "Jing Wang",
                "org": "Peking University(Peking University),Beijing,China"
            }
        ],
        "venue": "Chinese Journal of Neurology",
        "year": 2007
    },
    "b3XNZo5l": {
        "id": "b3XNZo5l",
        "title": "Primary Study of Acylated Ghrelin and Unacylated Ghrelin on Pancreatic β Cells",
        "abstract": "Objective:To investigate the effect of acylated ghrelin and unacylated ghrelin on pancreatic β cells,and study the pathway of their effect.Methods:Mouse pancreatic β cells were treated with different concentrations of acylated and unacylated ghrelin,NIT-1 cell proliferation were measured by MTT after 48 hours,subsequently NF449 was used to block the pathway of Gαs to check if the effect on pancreatic β cells of acylated ghrelin and unacylated ghrelin were through this way.Results:Both acylated ghrelin in the concentration beween 10(-9)~10(-7) mol/L and unacylated ghrelin between 10(-10)~10(-7) mol/L could promote the proliferation of pancreatic β cells,the way of which was Gαs pathway.Conclusions:Both acylated ghrelin and unacylated ghrelin can promote the proliferation of pancreatic β cells through Gαs pathway.",
        "keywords": [
            "Cell Proliferation/drug effects",
            "Islets of Langerhans/cytology/drug effects",
            "Peptide Hormones/pharmacology"
        ],
        "authors": [
            {
                "name": "LIU Rong-feng",
                "org": "Department of Laboratory,The Third Hospital of Peking University,Beijing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Laboratory,The Third Hospital of Peking University,Beijing ,China"
            }
        ],
        "venue": "Chinese Journal of Misdiagnostics",
        "year": 2008
    },
    "qifqGTrx": {
        "id": "qifqGTrx",
        "title": "Sensitivity analyses of linezolid against clinical gram-positive cocci isolates in vitro",
        "abstract": "AIM: To compare the antibacterial activity of linezolid with vancomycin and other antibacterials against clinical gram-positive cocci isolates in vitro.METHODS: The antibacterial activity of linezolid and other antibacterials were determined according to the disk diffusion guidelines of NCCLS(CLSI) 2007 in vitro.RESULTS: The incidence of methicillin-resistant Staphylococcus aureus(MRSA) isolated in our hospital was 79.1%,linezolid showed great susceptibility as well as vancomycin and teicoplanin.The incidence of methicillin-resistant coagulase negative Staphylococcus(MRCNS,88.9%) was higher than that of MRSA,the antibacterial activity of linezolid was comparable with that of vancomycin and teicoplanin,and the sensitivity was 100%.The activity of linezolid against enterococcus faecalis is similar to that of vancomycin and teicoplanin,the activity of linezolid against enterococcus faecium is prior to that of vancomycin and teicoplanin(100%,80.4%,78.1%).Linezolid also showed great activity against penicillin resistant streptococcus pneumonia(PRSP).CONCLUSION: The antibacterial activity of linezolid was comparable with that of vancomycin and teicoplanin against MRSA,MRCNS,PRSP and enterococcus faecalis,and the sensitivity were all 100%.The antibacterial activity was better than those of the two drugs against enterococcus faecium in vitro.Linezolid could be a promising therapeutic option to treat infections caused by multi-resistant gram-positive cocci.",
        "keywords": [
            "sensitivity",
            "linezolid",
            "vancomycin",
            "in vitro",
            "multidrug resistance",
            "gram-positive cocci"
        ],
        "authors": [
            {
                "name": "XIAO Xiu-mei",
                "org": " Department of Laboratory Medicine,Third Hospital of Peking University,Beijing ,China"
            },
            {
                "name": "ZHANG Xiao-wei",
                "org": " Department of Laboratory Medicine,Third Hospital of Peking University,Beijing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": " Department of Laboratory Medicine,Third Hospital of Peking University,Beijing ,China"
            }
        ],
        "venue": "Chinese Journal of Clinical Pharmacology and Therapeutics",
        "year": 2008
    },
    "AGzxKmsB": {
        "id": "AGzxKmsB",
        "title": "Establishment of IMA Reference Intervals of Han Populations in Beijing area",
        "abstract": "Objective:To establishe the reference intervals of IMA on automatic biochemical analyzer.Methods:IMA were detected by Hitachi 7170A autobiochemical analyzer with albumin cobalt binding test.IMA reference intervals were established by 561 healthy controls.Results:5% lower limit values in the subjects lower and old 30 years were 67 U/ml and 64 U/ml respectively.Conclusions:The reference intervals of IMA are established on automatic biochemical analyzer with ACB test.It should be helpful for clincal diagnosis on myocardial ischemia.",
        "keywords": [
            "Reference Values",
            "HAN NATIONALITY",
            "Humans",
            "BEIJING",
            "Serum Albumin/analysis"
        ],
        "authors": [
            {
                "name": "CUI Li-yan",
                "org": "Deparment of Laboratory Medicine,The Third Hospital of Peking University,Beijing ,China"
            },
            {
                "name": "LI Jing",
                "org": "Deparment of Laboratory Medicine,The Third Hospital of Peking University,Beijing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Deparment of Laboratory Medicine,The Third Hospital of Peking University,Beijing ,China"
            }
        ],
        "venue": "Chinese Journal of Misdiagnostics",
        "year": 2008
    },
    "0C1diEun": {
        "id": "0C1diEun",
        "title": "Evaluation of Threshold of Parameter on Bacterial Particle of Automated Urine Flow Cytometry UF-100",
        "abstract": "Objective:To evaluate the threshold of parameter on bacterial particle of UF-100.Method:Urine quantitative cultures of 462 samples from hospitalized patients were used as a reference method for comparison.Threshold of parameter on bacterial particle was determined by ROC curve.The association between the quantity of bacterial particle measured by UF-100 and the quantity of urine cultures was demostrated by regression curve.Results:The threshold of bacterial particle were 5 459/μl,6 520/μl and 8 092/μl compared with culture at a cutoff of 102 CFU/ml,104 CFU/ml and 105 CFU/ml,respectively.The threshold of bacterial particle were influenced by gender and species of pathogen. The regression curves of the quantity(X) of bacterial particle and the logarithm(Y) of the quantity of cultures were Y=1.930 2+0.000 2X and Y=-6.141 2+1.121 4×lnX.Conclusions:The threshold of bacterial particle is determined by urine quantitative culture and influenced by gender and species of pathogen.The results of urine culture can be estimated by the regression curve.",
        "keywords": [
            "Colony Count",
            "Urinalysis/instrumentation",
            "Microbial"
        ],
        "authors": [
            {
                "name": "NING Yong-zhong",
                "org": "Third Hospital of Peking University,Beijing ,China"
            },
            {
                "name": "MA Ji-zhi",
                "org": "Third Hospital of Peking University,Beijing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Third Hospital of Peking University,Beijing ,China"
            }
        ],
        "venue": "Chinese Journal of Misdiagnostics",
        "year": 2009
    },
    "SFX9lYNA": {
        "id": "SFX9lYNA",
        "title": "The evaluation of Ketoamine oxidase method to determinate glycated albumin",
        "abstract": "Objective To evaluate Ketoamine oxidase method of determinating glycated albumin(GA).Methods To evaluate Lucica GA-L kit by studying the imprecision,dilution linearity,recovery,interference factors,and reagent stability.Analyze the correlation between GA and glycated hemoglobin(HbA1c);GA and fructosamine(GSP,NBT method).Compare bromocresol green method(BCG) with bromocresol purple method(BCP) of albumin determination.The results showed good precision,within-run CV <1.4%,between-run CV <2.4%;good linearity;the average recovery rate of 96.74% for GA,and the average recovery rate of 96.73% for ALB.Glucose,chyle and bilirubin had no significant interference on GA,but the hemoglobin affected the results of over 10% when the concentration was over 1.82 g/L.Results was stable for more than 4 weeks.It showed excellent correlation(r=0.894 0,P<0.001) between GA and HbA1c.Determination of albumin values with BCG method(±s,37.1 ±8.4 g/L) were higher than that of BCP method(±s,33.3±10.0 g/L),but with excellent correlation(r=0.990 8,P<0.001).When ALB concentration was over 30 g/L,GA was well correlated to GSP(r=0.847 4,P<0.001);When ALB concentration was less than 30 g/L,they were in poor correlation(r=0.569 7,P<0.05).Conclusion This method of GA determination shows good performance,and it can calculate the ratio of GA and albumin.There are fewer interference factors affecting this method.This method is a good index to monitor short-term average blood glucose levels.",
        "keywords": [
            "diabetes mellitus",
            "glycated albumin",
            "glycated hemoglobin",
            "fructosamine"
        ],
        "authors": [
            {
                "name": "JIA Ke-ke",
                "org": "Laboratory Medicine Department,Peking University Third Hospital,Beijing ,China"
            },
            {
                "name": "LI Guo-quan",
                "org": "Laboratory Medicine Department,Peking University Third Hospital,Beijing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Laboratory Medicine Department,Peking University Third Hospital,Beijing ,China"
            }
        ],
        "venue": "Chinese Journal of Laboratory Diagnosis",
        "year": 2010
    },
    "hHZ37Pig": {
        "id": "hHZ37Pig",
        "title": "The value of combination determination of heart-type fatty acid binding protein and ischemia-modified albumin in patients with acute coronary syndrome and without increased troponin T level",
        "abstract": "Objective To investigate the diagnostic efficiency of the combination determination of heart-type fatty acid binding protein(H-FABP) as a marker for ongoing myocardial damage and ischemia-modified albumin(IMA) as a marker for myocardial ischemia in patients with acute coronary syndrome(ACS).Methods The levels of IMA and H-FABP were measured in 108 patients with chest pain,including 82 patients with ACS and 26 patients with non-ischemia chest pain(NICP).Serum IMA was measured by albumin cobalt binding(ACB) test.H-FABP was measured by immunochromatography assay.Results Serum samples from ACS group had decreased level of ACB [64(61-67)U/mL] compared with NICP group samples [75(71-78)U/mL](P<0.05).The optimum diagnostic cut-off value for ACB level was 70.5 U/mL by reciver operating characteristic(ROC) curve analysis.When ACB level <71.0 U/mL,the sensitivity was 89.0%,and the specificity was 80.8%.The area under ROC curve(AUC) was 0.876 [95% confidence interval(CI): 0.783-0.970].The positive predictive value and negative predictive value were 93.6% and 70.0% respectively.The sensitivity and specificity of H-FABP were 82.9% [95%CI: 74.8%-91.0%] and 80.8% [95%CI: 65.7%-95.9%] respectively.The diagnostic accuracy was 82.4% [95%CI: 75.2%-89.6%].The sensitivity and specificity of combination determination of IMA and H-FABP were 96.3% [95%CI: 96.2%-100.0%] and 80.8% [95%CI: 65.7%-95.9%] respectively.The diagnostic accuracy was 92.6% [95%CI: 87.7%-97.5%].The combination determination of IMA and H-FABP had a significant better sensitivity and diagnostic accuracy than the other biomarker assays(P<0.05).The positive predictive value and negative predictive value were 94.0% and 87.5% respectively.Conclusions The combination determination of IMA and H-FABP after initiation of chest pain may improve the diagnostic efficiency for ACS in patients without increased troponin T level.",
        "keywords": [
            "Myocardial ischemia",
            "Acute coronary syndrome",
            "Ischemia-modified albumin",
            "Fatty acid binding protein"
        ],
        "authors": [
            {
                "name": "CUI Liyan",
                "org": "Department of Clinical Laboratory,Third Hospital,Peking University,Beijing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Clinical Laboratory,Third Hospital,Peking University,Beijing ,China"
            },
            {
                "name": "HU Xiaozhou",
                "org": "Department of Clinical Laboratory,Third Hospital,Peking University,Beijing ,China"
            }
        ],
        "venue": "Laboratory Medicine",
        "year": 2010
    },
    "9q1GN9OK": {
        "id": "9q1GN9OK",
        "title": "Investigation on the relationship between serum sex hormone binding globulin level and coronary atherosclerosis in elderly males",
        "abstract": "Objective To investigate the relationship between serum sex hormone binding globulin ( SHBG) level and coronary atherosclerosis ( CAS) ,especially the risk factor of metabolic disorder,in elderly males,and discuss the role of SHBG in the formation of CAS. Methods 90 elderly male inpatients who received coronary angiography were classified into two groups:CAS group( 75 cases) and control group( 15 cases). The levels of SHBG,fasting blood glucose and blood lipid were determined in the first 24 h after hospitalization. The difference between the two groups were evaluated. The relationship between SHBG and other markers of metabolism was analyzed. The correlation of SHBG and CAS was also analyzed. Results There was significant difference in SHBG levels between the two groups ( P < 0. 01). There were inverse correlations of SHBG with body mass index ( BMI) ,low density lipoprotein-cholesterol ( LDL-C) and fasting blood glucose( r = -0. 239,-0. 965 and -0. 272,P < 0. 05). There were not significant correlations of SHBG with total cholesterol ( TC) ,triglyceride ( TG) ,high density lipoprotein-cholesterol ( HDL-C) and high sensitive C reactive protein ( hs-CRP). Fasting blood glucose,LDL-C and SHBG were the independent factors for CAS,and the odd ratio ( OR) of SHBG was 2. 81. Conclusions The level of SHBG is different in the elderly male CAS patients. Low SHBG may be an important independent factor for CAS in elderly males.",
        "keywords": [
            "Coronary atherosclerosis",
            "Sex hormone binding globulin",
            "Elderly male"
        ],
        "authors": [
            {
                "name": "HU Xiaozhou",
                "org": " Department of Clinical Laboratory,Peking University Third Hospital,Beijing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": " Department of Clinical Laboratory,Peking University Third Hospital,Beijing ,China"
            }
        ],
        "venue": "Laboratory Medicine",
        "year": 2010
    },
    "d4DNgeIu": {
        "id": "d4DNgeIu",
        "title": "Effects of TNF-α on expression of NGAL in HK-2 cells after ischemia reperfusion injury",
        "abstract": "Objective To investigate the effects of TNF-α on the expression of NGAL in HK-2 cells after ischemia reperfusion injury.Methods The ischemia reperfusion model of HK-2 cells was established in vitro.The expressions of NGAL gene with different ischemic time and concentration of TNF-α were detected by using RT-PCR.Results Our datas showed that the NGAL level in cells significantly increased,and ischemia for 1 h,2 h,4 h before reperfusion was higer than 0.5 h.The expression of NGAL gene could enhance with the increased concentration of TNF-α.Conclusion The expression of NGAL enhanced significantly after ischemia reperfusion,and the production of TNF-α can increase the NGAL gene level.",
        "keywords": [
            "Kidney Tubules/cytology",
            "Tumor Necrosis Factor-alpha",
            "Epithelial Cells/metabolism",
            "Proto-Oncogene Proteins/metabolism",
            "Anoxia/pathology",
            "Lipocalins/metabolism",
            "Acute-Phase Proteins/metabolism"
        ],
        "authors": [
            {
                "name": "YANG Shuo",
                "org": " Laboratory Medicine Department,The Third Hospital of Peking University,Beijing ,China"
            },
            {
                "name": "CUI Li-yan",
                "org": " Laboratory Medicine Department,The Third Hospital of Peking University,Beijing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": " Laboratory Medicine Department,The Third Hospital of Peking University,Beijing ,China"
            }
        ],
        "venue": "Chinese Journal of Misdiagnostics",
        "year": 2011
    },
    "Ca0TwMrj": {
        "id": "Ca0TwMrj",
        "title": "Construction and identification of luciferase reporter gene vector containing LCN2 promoter",
        "abstract": "Objective To clone the coding sequence of LCN2 gene,establish LCN2 containing luciferase reporter system and further express LCN2 in renal tubular epithelial cell strain HK-2.Methods Reverse transcription polymerase chain reaction(RT-PCR) was performed based on the RNA module extracted from human renal tubular epithelial cell strain HK-2.The product for amplification was cloned to the oriented reporter gene vector PGL3-Basic after being cleaved by HindⅢ and SmaI,and was identified according to both the recombinant plasmid PGL3-Basic/LCN2 cleaved by restriction endonuclease and DNA sequencing.The recombined vector was transfected into HK-2 cells using the non lysosomal method,and the activity of the luriferase was determined after cells,selected by Amp for culture,and was identified using dual luriferase detection.Results PCR and sequencing results indicated that the amplified sequence was correct.The results of restriction enzyme digestion indicated that the recombinant vector PGL3-Basic/LCN2 was successfully constructed.The luciferase reporter system showed that the transcription activation of PGL3-Basic/LCN2 was significantly higher than PGL3-Basic(P<0.000 1).Conclusion The coding sequence of human LCN2 gene is successfully cloned in this study.The establishment of luciferase reporter gene vector PGL3-Basic/LCN2 may be helpful to the understanding of mechanism by which it influences the acute kidney injury in further studies.",
        "keywords": [
            "Kidney/injuries",
            "Proto-Oncogene Proteins/genetics",
            "Acute-Phase Proteins/genetics"
        ],
        "authors": [
            {
                "name": "CUI Li-yan",
                "org": "Department of Laboratory,Third Hospital of Peking University,Beijing ,China"
            },
            {
                "name": "YANG Shuo",
                "org": "Department of Laboratory,Third Hospital of Peking University,Beijing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Laboratory,Third Hospital of Peking University,Beijing ,China"
            }
        ],
        "venue": "Chinese Journal of Misdiagnostics",
        "year": 2011
    },
    "MQpAFkar": {
        "id": "MQpAFkar",
        "title": "Management of patients with severe pulmonary infection after renal transplantation",
        "abstract": "Objective:To investigate the characteristics of occurrence,diagnosis,and treatment of severe pulmonary infection in recipients of renal transplantation.Methodology:Clinical data of renal transplant recipients who were admitted to SICU because of severe pulmonary infection from 2002 to 2010 was retrospectively reviewed.Results:A total of fifteen renal transplant recipients with severe pulmonary infection during the 8-year period.Among them,the infection occurred within 6 months in 12(80.0%),and within 3 months in 9 cases(60.0%) after renal transplantation.12 patients were diagnosed as severe pneumonia(80.0%) and 6 were diagnosed as acute respiratory distress syndrome(40.0%).According to the place of occurrence,8 cases were hospital-acquired pneumonia(53.3%),and 7 were community-acquired pneumonia(46.7%).According to the pathogenic microorganism,12 cases were bacterial pneumonia,4 cases were fungal pneumonia,and one case was pneumocystis carinii pneumonia.No pathogen was identified in 3 cases.Among 12 cases with identified pathogen,4 were mixed infection(33.3%).After combining therapy,13 patients(86.7%) were cured,while 2(13.3%) were died.Conclusion:High attention should be paid to patients with severe pulmonary infection after renal transplantation.Early pathogenic diagnosis,aggressive antibiotic therapy according to pathogenic microorganism,prompt modulation of immunosuppressive therapy,reinforced supportive therapy,and mechanical ventilation when necessary to correct hypoxia are key elements of successful management.",
        "keywords": [
            "renal transplantation severe pulmonary infection treatment outcomes"
        ],
        "authors": [
            {
                "name": "QIAO Hong",
                "org": " Department of Anesthesiology and Surgical Intensive Care,Peking University First Hospital,Beijing ,China"
            },
            {
                "name": "WANG Dong-xin",
                "org": " Department of Anesthesiology and Surgical Intensive Care,Peking University First Hospital,Beijing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": " Department of Anesthesiology and Surgical Intensive Care,Peking University First Hospital,Beijing ,China"
            }
        ],
        "venue": "Chinese Journal of Nephrology,Dialysis & Transplantation",
        "year": 2011
    },
    "qvvHqGqJ": {
        "id": "qvvHqGqJ",
        "title": "Comparison on three methods in the examination of urine sediment",
        "abstract": "Objective To compare the performances of UF-1000i urine sediment analyzer,dry chemistry method and manual microscopy in the determinations of red blood cell(RBC) and white blood cell(WBC).Methods 996 urine samples were collected.The RBC and WBC were determined by UF-1000i urine sediment analyzer,dry chemistry method and manual microscopy.The results were compared and analyzed statistically.Results With the positive cut-off value of 25 per μL for RBC and 30 per μL for WBC,the complete concordances were 78.4% for RBC and 67.2% for WBC.The concordances defined by the grade between the 2 analyzers were found to be 85.6% for RBC and 86.5% for WBC.The false positive rates of the UF-1000i were 4.62% for RBC and 1.81% for WBC.Conclusions These 3 urinalysis methods show good concordance with each other in urine sediment examination.The UF-1000i is more accuracy and anti-interferential than UF-100,but manual microscopy is still necessary.",
        "keywords": [
            "Red blood cell",
            "UF-1000i urine sediment analyzer",
            "White blood cell"
        ],
        "authors": [
            {
                "name": "HU Xiaozhou",
                "org": "Department of Clinical Laboratory,Peking University Third Hospital,Beijing ,China"
            },
            {
                "name": "CUI Yanmei",
                "org": "Department of Clinical Laboratory,Peking University Third Hospital,Beijing ,China"
            },
            {
                "name": "WANG Xiaolin",
                "org": "Department of Clinical Laboratory,Peking University Third Hospital,Beijing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Clinical Laboratory,Peking University Third Hospital,Beijing ,China"
            }
        ],
        "venue": "Laboratory Medicine",
        "year": 2011
    },
    "sSKzyrWa": {
        "id": "sSKzyrWa",
        "title": "Intrahospital dissemination of carbapenem-resistant Acinetobacter baumannii and analysis of the infected patients' prognosis.",
        "abstract": "To assess the genetic relationship of clinical isolates of carbapenem-resistant A. baumannii(resistant to both imipenem and meropenem) from January 2007 to March 2008 in Peking University Third Hospital for measures to decrease the isolates; to investigate the characteristics of patients with carbapenem-resistant A.baumannii colonization or infection and to evaluate antibiotic treatment for health care-associated infections caused by carbapenem-resistant A.baumannii.The medical records of patients with carbapenem-resistant A. baumannii colonization or infection were reviewed. Antibiotic susceptibilities of the isolates were determined by the standardized disk-diffusion method and the clonal relationship of the isolates was analyzed by pulsed-field gel electrophoresis.A total of 49 carbapenem-resistant A. baumannii strains were isolated from the 49 patients hospitalized during the study period and pulsed-field gel electrophoresis typing yielded 7 different patterns. A total of 45 (91.8%) genotyped strains showed clonal relationship. The most frequently identified predisposing factors were intensive care unit stay, invasive procedures, and hypoalbuminemia. Chronic obstructive pulmonary disease (12 cases) and cerebrovascular disease (10 cases) were the most common comorbid conditions. The mortality of patients with carbapenem-resistant A. baumannii infection was 38.1% (8 of 21 patients), and the acute physiology and chronic health evaluation II score, initial antibiotic therapy failure rate and the presence of hypoalbuminemia were significantly increased in the death group. Combination therapy regimens had higher success rates than monotherapy regimens(11/13, 84.6% vs. 3/17, 17.6%).There has been clonal spread of carbapenem-resistant A. baumannii strains among patients in our hospital since 2007. Intensive care unit stay, invasive procedures, hypoalbuminemia, chronic obstructive pulmonary disease and cerebrovascular disease were common in patients with carbapenem-resistant A. baumannii colonization or infection. Antibiotic combination therapy may be effective for carbapenem-resistant A. baumannii infection.",
        "keywords": [
            "drug resistance",
            "gel",
            "acinetobacter baumannii",
            "cross infection",
            "drug therapy",
            "pulsed-field",
            "electrophoresis",
            "combination"
        ],
        "authors": [
            {
                "name": "Qing-tao Zhou",
                "org": "1.Department of Respiratory Medicine,"
            },
            {
                "name": "Bei He",
                "org": "1.Department of Respiratory Medicine,"
            },
            {
                "name": "Bei Yao",
                "org": "2.Department of Clinical Laboratory,Peking University Third Hospital,Beijing ,China"
            },
            {
                "name": "Zhen-ying Liu",
                "org": "2.Department of Clinical Laboratory,Peking University Third Hospital,Beijing ,China"
            },
            {
                "name": "Jie Zhang",
                "org": "2.Department of Clinical Laboratory,Peking University Third Hospital,Beijing ,China"
            }
        ],
        "venue": "Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences",
        "year": 2011
    },
    "D5rp7eLO": {
        "id": "D5rp7eLO",
        "title": "Pre-analytical quality of common clinical samples of bacteriology and mycology",
        "abstract": "Objection To study the pre-analytical quality of common clinical samples of bacteriology and mycology.Method To analyse the ratio of unacceptable or wrong blood,expecutored sputum,urine and faces specimen for microbiological culture.Result There were 565 set blood samples from 495 case between July and September 2009 in the Third Hospital of Peking University.46 samples had positive growth.The contamination ratio was 2.6%.The mean volume was 7.0 ml in aerobic bottle and 7.2 ml in anaerobic bottle.The volume was lower than 5 ml in 15.30% bottles and 6.5% sets.The case ratio that the sets are equal or more than 2 is 11.7% and the set ratio that were equal or more than 2 was 22.6%.91.3% catheters were shorter than 5 cm,and 26.1% shorter than 2.5 cm.The ratio of unacceptable sputum samples was 39.4%.The contaminated growth ratio of urine samples was 3.1%.The ratio of unacceptable stool samples from adult cases in whole hospital was 63.9%,that was 90.2% in the non-Gastroenterological cases.Conclusion There are some unacceptable or wrong samples in the clinical practice.",
        "keywords": [
            "Bacteriological Techniques",
            "Quality Control"
        ],
        "authors": [
            {
                "name": "NING Yong-zhong",
                "org": " Department of Laboratory Medicine,The Third Hospital of Peking University,Beijing "
            },
            {
                "name": "ZHANG Shu-ying",
                "org": " Department of Laboratory Medicine,The Third Hospital of Peking University,Beijing "
            },
            {
                "name": "ZHANG Jie",
                "org": " Department of Laboratory Medicine,The Third Hospital of Peking University,Beijing "
            }
        ],
        "venue": "Chinese Journal of Misdiagnostics",
        "year": 2011
    },
    "k11vLXk8": {
        "id": "k11vLXk8",
        "title": "Establishment of Reference Method for Serum Urea Detection and Comparison with Routine Urea Kits",
        "abstract": "Objective To establish and validate the coupled-enzyme equilibrium reference method as a reference method for urea detection and compare it with other 4 routine urea kits. Methods The reference method was verified by testing the two levels of urea in SRM909b and participating in RELA-2009.The EP9-A2 protocol was used to compare the results in forty serum samples in 4 routine kits methods with coupled-enzyme equilibrium reference method. Results The deviation of SRM909b level 1 was 2.19% and SRM 909b level 2 were 0.24% respectively through determining by the reference method.The results for RELA-2009 were within the accepted range.Comparing the confidence interval of the predicted bias with the definition acceptable error at the medical decision point Xc(Xc=9.64 mmol/L) for the 4 routine kits,the results were all within the range of defined acceptable error(4.5%) and the range of biological variation bias(5.5%). Conclusion The coupled-enzyme equilibrium reference method for serum urea was established in our lab.The urea results measured with 4 routine kits were different from results with the reference method,but the deviation was acceptable,and it will not affect the detection results.",
        "keywords": [
            "spectrophotometry",
            "urea",
            "evaluation study",
            "ultraviolet",
            "reference method",
            "coupled-enzyme equilibrium"
        ],
        "authors": [
            {
                "name": "ZHANG Ya-jun",
                "org": "Department of Clinical Laboratory,Peking University Third Hospital"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Clinical Laboratory,Peking University Third Hospital"
            }
        ],
        "venue": "Journal of Capital Medical University",
        "year": 2011
    },
    "SNK9BBEV": {
        "id": "SNK9BBEV",
        "title": "Analysis on the infection status of TORCH in 19 500 infertile women and 4 141 pregnant women",
        "abstract": "Objective:To understand the infection status of TORCH in infertile women and pregnant women.Methods:A total of 19 500 infertile women at childbearing age and 4 141 pregnant women were selected as research objects,ELISA was used to detect TORCH-IgM antibody.Results:The positive rates of Toxoplasma IgM antibody,Rubella virus IgM antibody,Cytomegalovirus IgM antibody,and Herpes simplex virus IgM antibody in infertile women were 0.04%,0.19%,0.54%,and 0.27%,respectively,the total positive rate was 0.89%;the positive rates of Toxoplasma IgM antibody,Rubella virus IgM antibody,Cytomegalovirus IgM antibody,and Herpes simplex virus IgM antibody in pregnant women were 0.12%,0.29%,0.87%,and 0.39%,respectively,the total positive rate was 1.47%.Conclusion:The infective rate of TORCH is low among the infertile women and pregnant women in Beijing city,the total infective rate of TORCH in infertile women is lower than that in pregnant women,the relationship between TORCH infection and infertility is not clear.",
        "keywords": [
            "Infertility",
            "TORCH infection",
            "ELISA"
        ],
        "authors": [
            {
                "name": "YAO Bei",
                "org": ".The Third Hospital of Beijing University,Beijing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": ".The Third Hospital of Beijing University,Beijing ,China"
            }
        ],
        "venue": "Maternal and Child Health Care of China",
        "year": 2012
    },
    "R0H4ipn1": {
        "id": "R0H4ipn1",
        "title": "Characterization of small defects using ultrasonic arrays: a scattering coefficient matrix approach",
        "abstract": "The ultrasonic scattering coefficient matrix define s the far field scattering behaviour of a defect as a function of incident and scattering ang les. An ultrasonic array with a large aperture can then be used to interrogate a defect o ver a range of angles and hence extract parts of this matrix. Experimental results are pres ented using a commercial 64-element, 5-MHz array on two aluminium test samples that contain a number of simulated defects including machined slots and side-drilled circular holes. A sub-array approach is used in which a group of 8 elements are excited in order in terrogate the defect from a given angle as well as providing spatial discrimination. In th is way a neighbouring circular hole and slot can be spatially resolved and clearly distingu ished by their different scattering coefficients over a range of incident angles and sc attering angles. Using signals reflected from a known-size side-drilled circular hole as the reference, scattering coefficients of a defect can be normalized. These measured scattering coefficients show a good agreement with scattering coefficients predicted from finite element modelling. For example, the orientations of defects directly below the array ar e extracted to an accuracy of a few degrees and their lengths were determined with an e rror of ±10%.",
        "keywords": [
            "defect c haracterization",
            "finite element analysis",
            "scattering coefficient",
            "ultrasonic arrays"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Department of Mechanical Engineering|University Walk|University of Bristol"
            },
            {
                "name": "Bruce W. Drinkwater",
                "org": "Department of Mechanical Engineering|University Walk|University of Bristol"
            },
            {
                "name": "Paul D. Wilcox",
                "org": "Department of Mechanical Engineering|University Walk|University of Bristol"
            }
        ],
        "venue": "",
        "year": 0
    },
    "3JY1txmH": {
        "id": "3JY1txmH",
        "title": "Calibration of the ultrasonic lubricant-film thickness measurement technique",
        "abstract": "",
        "keywords": [
            "resonant frequency",
            "ultrasound",
            "reflection coefficient"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Bruce W Drinkwater",
                "org": ""
            },
            {
                "name": "Rob S Dwyer-Joyce",
                "org": ""
            }
        ],
        "venue": "Measurement Science & Technology",
        "year": 2005
    },
    "tQbSx50w": {
        "id": "tQbSx50w",
        "title": "Monitoring of Lubricant Film Failure in a Ball Bearing Using Ultrasound",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Bruce W. Drinkwater",
                "org": ""
            },
            {
                "name": "Rob S. Dwyer-Joyce",
                "org": ""
            }
        ],
        "venue": "Journal of Tribology-transactions of The Asme",
        "year": 2006
    },
    "Uf8lcajA": {
        "id": "Uf8lcajA",
        "title": "Acoustic measurement of lubricant-film thickness distribution in ball bearings",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Bruce W. Drinkwater",
                "org": ""
            },
            {
                "name": "Rob S. Dwyer-Joyce",
                "org": ""
            }
        ],
        "venue": "Journal of The Acoustical Society of America",
        "year": 2006
    },
    "KFGBoSCB": {
        "id": "KFGBoSCB",
        "title": "The Measurement of Oil Film Thickness in Ball Bearings Using Ultrasound",
        "abstract": "",
        "keywords": [
            "reflection coefficient",
            "lubrication theory",
            "industrial production",
            "ultrasonic testing",
            "early warning",
            "ultrasound",
            "nondestructive testing",
            "operant conditioning"
        ],
        "authors": [
            {
                "name": "jie zhang",
                "org": "university of bristol"
            },
            {
                "name": "bruce w drinkwater",
                "org": "university of bristol"
            },
            {
                "name": "r s dwyerjoyce",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2006
    },
    "MSTBBeAt": {
        "id": "MSTBBeAt",
        "title": "Ultrasonic oil-film thickness measurement: an angular spectrum approach to assess performance limits.",
        "abstract": "The performance of ultrasonic oil-film thickness measurement in a ball bearing is quantified. A range of different viscosity oils (Shell T68, VG15, and VG5) are used to explore the lowest reflection coefficient and hence the thinnest oil-film thickness that the system can measure. The results show a minimum reflection coefficient of 0.07 for both oil VG15 and VG5 and 0.09 for oil T68 at 50 MHz. This corresponds to an oil-film thickness of 0.4 microm for T68 oil. An angular spectrum (or Fourier decomposition) approach is used to analyze the performance of this configuration. This models the interaction of component plane waves with the measurement system and quantifies the effect of the key parameters (transducer aperture, focal length, and center frequency). The simulation shows that for a focused transducer the reflection coefficient tends to a limiting value at small oil-film thickness. For the transducer used in this paper it is shown that the limiting reflection coefficient is 0.05 and the oil-film measurement errors increase as the reflection coefficient approaches this value. The implications for improved measurement systems are then discussed.",
        "keywords": [
            "spectrum"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Bruce W Drinkwater",
                "org": ""
            },
            {
                "name": "Rob S Dwyer-Joyce",
                "org": ""
            }
        ],
        "venue": "The Journal of the Acoustical Society of America",
        "year": 2007
    },
    "sSAc2LCA": {
        "id": "sSAc2LCA",
        "title": "Ultrasonic oil-film thickness measurement",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "bruce w drinkwater",
                "org": ""
            },
            {
                "name": "r s dwyerjoyce",
                "org": ""
            }
        ],
        "venue": "Journal of the Acoustical Society of America",
        "year": 2007
    },
    "PP6vKOTJ": {
        "id": "PP6vKOTJ",
        "title": "ULTRASONIC MEASUREMENT OF ROLLING ELEMENT BEARING LUBRICATION USING PIEZOELECTRIC THIN FILM TRANSDUCERS",
        "abstract": "",
        "keywords": [
            "ultrasound",
            "high frequency",
            "lubrication theory",
            "thin film",
            "reflection coefficient"
        ],
        "authors": [
            {
                "name": "bruce w drinkwater",
                "org": "university of bristol"
            },
            {
                "name": "jie zhang",
                "org": "university of bristol"
            },
            {
                "name": "k j kirk",
                "org": "university of the west of scotland"
            },
            {
                "name": "j elgoyhen",
                "org": "university of the west of scotland"
            },
            {
                "name": "r s dwyerjoyce",
                "org": "university of sheffield"
            }
        ],
        "venue": "",
        "year": 2008
    },
    "mvWPqK25": {
        "id": "mvWPqK25",
        "title": "Defect characterization using ultrasonic arrays",
        "abstract": "",
        "keywords": [
            "matrices",
            "time domain",
            "scattering",
            "scattering matrix",
            "data processing",
            "transmitters",
            "system design",
            "inspection",
            "transducers",
            "nondestructive evaluation",
            "ultrasonography"
        ],
        "authors": [
            {
                "name": "paul d wilcox",
                "org": "university of bristol"
            },
            {
                "name": "jie zhang",
                "org": "university of bristol"
            },
            {
                "name": "bruce w drinkwater",
                "org": "university of bristol"
            }
        ],
        "venue": "",
        "year": 2008
    },
    "McMGKGyq": {
        "id": "McMGKGyq",
        "title": "Thin oil-film thickness distribution measurement using ultrasonic arrays",
        "abstract": "",
        "keywords": [
            "reflection coefficient"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Department of Mechanical Engineering, University of Bristol, University Walk, Bristol BS8 1TR, UK"
            },
            {
                "name": "Bruce W. Drinkwater",
                "org": ""
            }
        ],
        "venue": "NDT and E International",
        "year": 2008
    },
    "5Qv6j2Ul": {
        "id": "5Qv6j2Ul",
        "title": "Ultrasonic Measurement of Rolling Bearing Lubrication Using Piezoelectric Thin Films",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Bruce W. Drinkwater",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Katherine J. Kirk",
                "org": ""
            },
            {
                "name": "Jocelyn Elgoyhen",
                "org": ""
            },
            {
                "name": "Rob S. Dwyer-Joyce",
                "org": ""
            }
        ],
        "venue": "Journal of Tribology-transactions of The Asme",
        "year": 2009
    },
    "PFp15lba": {
        "id": "PFp15lba",
        "title": "THE CHARACTERIZATION OF CRACK-LIKE DEFECTS USING ULTRASONIC IMAGES",
        "abstract": "",
        "keywords": [
            "nondestructive testing",
            "acoustic emission",
            "industrial production",
            "look up table",
            "fourier optics",
            "fourier transform",
            "matrix theory",
            "image features",
            "scattering matrix",
            "nondestructive evaluation"
        ],
        "authors": [
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "alexander velichko",
                "org": ""
            },
            {
                "name": "bruce w drinkwater",
                "org": "university of bristol"
            },
            {
                "name": "paul d wilcox",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2010
    },
    "nsso6OC0": {
        "id": "nsso6OC0",
        "title": "Defect detection using ultrasonic arrays: The multi-mode total focusing method",
        "abstract": "Ultrasonic arrays allow a given scatterer to be illuminated from a wide range of angles and hence are capable of extracting significant information about the scatterer. In this paper a general imaging methodology, termed multi-mode total focusing method, is proposed in which any combination of modes and reflections can be used to produce an image of the test structure. Like the total focusing method, this approach is implemented by post-processing the full matrix of array data to achieve a synthetic focus at every pixel in the image. A hybrid model is used to predict the array data and demonstrate the performance of the multi-mode imaging concept. This hybrid model combines far field scattering coefficient matrices with a ray-based wave propagation model. This allows the inclusion of longitudinal waves, shear waves and wave mode conversions. It is shown that, with prior knowledge of likely scatterer location and orientation, the mode combination and array location can be optimised to maximise the performance of array inspections. A practically relevant weld inspection application is then described and its optimisation is discussed.",
        "keywords": [
            "non-destructive testing",
            "scattering coefficient matrix",
            "ultrasonic arrays",
            "non destructive testing",
            "wave propagation"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Bruce W. Drinkwater",
                "org": "Department of Mechanical Engineering, University Walk, University of Bristol, Bristol BS8 1TR, UK"
            },
            {
                "name": "Paul D. Wilcox",
                "org": "Department of Mechanical Engineering, University Walk, University of Bristol, Bristol BS8 1TR, UK"
            },
            {
                "name": "Alan J. Hunter",
                "org": "Department of Mechanical Engineering, University Walk, University of Bristol, Bristol BS8 1TR, UK"
            }
        ],
        "venue": "NDT and E International",
        "year": 2010
    },
    "DJ9RjKE0": {
        "id": "DJ9RjKE0",
        "title": "The Use of Ultrasonic Arrays to Characterize Crack-Like Defects",
        "abstract": "",
        "keywords": [
            "time domain",
            "scattering matrix"
        ],
        "authors": [
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "bruce w drinkwater",
                "org": "university of bristol"
            },
            {
                "name": "paul d wilcox",
                "org": ""
            }
        ],
        "venue": "Journal of Nondestructive Evaluation",
        "year": 2010
    },
    "QeYYrDST": {
        "id": "QeYYrDST",
        "title": "The Use of Ultrasonic Arrays to Characterize Crack-Like Defects",
        "abstract": "The use of ultrasonic arrays to image and size crack-like defects is an important area in non-destructive evaluation. In this\n paper, two approaches are considered for extracting the key parameters of crack length and orientation angle. The parameters\n for small cracks are inferred from the scattering matrix. For larger cracks, the parameters are extracted directly from a\n high resolution image. The performance of both techniques is first assessed using a hybrid model to generate the full matrix\n of array data for a specified inspection configuration. The model combines a ray-based propagation model with scattering matrices\n to describe wave interaction with a defect. Good agreement is achieved between simulated and experimental results, hence validating\n this model-based approach. This model is then used to assess the impact of time-domain noise on the characterisation of crack-like\n defects. For the low-noise case, the scattering matrix approach shows good performance if the crack length is greater than\n 0.2 wavelengths and the image-based approach is good for crack lengths greater than 0.5 wavelengths. The scattering-matrix-based\n approach is found to be more sensitive to the addition of noise than the image-based approach. Finally, both techniques are\n demonstrated experimentally on samples containing more realistic defects.",
        "keywords": [
            "ultrasonic arrays · defect characterization · scattering coefficient · total focusing method",
            "Ultrasonic arrays",
            "Defect characterization",
            "Scattering coefficient",
            "Total focusing method"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Department of Mechanical Engineering, University Walk, University of Bristol, Bristol, BS8 1TR UK"
            },
            {
                "name": "Bruce W. Drinkwater",
                "org": "Department of Mechanical Engineering, University Walk, University of Bristol, Bristol, BS8 1TR UK"
            },
            {
                "name": "Paul D. Wilcox",
                "org": "Department of Mechanical Engineering, University Walk, University of Bristol, Bristol, BS8 1TR UK"
            }
        ],
        "venue": "Journal of Nondestructive Evaluation",
        "year": 2010
    },
    "YRQrp68w": {
        "id": "YRQrp68w",
        "title": "Acoustic-radiation-force manipulation of microparticles using phase-controllable ultrasonic standing waves",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "c r p courtney",
                "org": ""
            },
            {
                "name": "c k ong",
                "org": ""
            },
            {
                "name": "bruce w drinkwater",
                "org": ""
            },
            {
                "name": "paul d wilcox",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "christine e m demore",
                "org": ""
            },
            {
                "name": "sandy cochran",
                "org": ""
            },
            {
                "name": "peter glynnejones",
                "org": ""
            },
            {
                "name": "michael d hill",
                "org": ""
            },
            {
                "name": "a l bernassau",
                "org": ""
            },
            {
                "name": "d r s cumming",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2011
    },
    "k2JlItl2": {
        "id": "k2JlItl2",
        "title": "A STUDY INTO THE EFFECTS OF AN AUSTENITIC WELD ON ULTRASONIC ARRAY IMAGING PERFORMANCE",
        "abstract": "",
        "keywords": [
            "nondestructive testing",
            "industrial production",
            "image quality",
            "data acquisition"
        ],
        "authors": [
            {
                "name": "a j hunter",
                "org": ""
            },
            {
                "name": "bruce w drinkwater",
                "org": "university of bristol"
            },
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "paul d wilcox",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2011
    },
    "AB1Kcoqh": {
        "id": "AB1Kcoqh",
        "title": "Effects of array transducer inconsistencies on total focusing method imaging performance",
        "abstract": "The total focusing method (TFM) is a post-processing imaging algorithm for ultrasonic array data in which the array is synthetically focused at every image pixel. In this paper, the performance of the TFM imaging algorithm is examined in the presence of inter-element variability in the array, coupling and instrumentation. The inter-element variability includes amplitude, phase and delay inconsistencies. First, typical experimentally observed inter-element variations are extracted by back-propagation of the pulse-echo signals reflected from the planar back wall of a defect-free sample. The effect of different degrees of variability in the amplitude, phase and time delay associated with each element is then investigated through simulation. The peak amplitude and a measure of the size of the point spread function are used to assess the quality of TFM images simulated for a 1 mm side-drilled hole. It is shown that the performance is most sensitive to variability of time-delay rather than amplitude or phase.",
        "keywords": [
            "total focusing method",
            "non-destructive testing",
            "ultrasonic arrays",
            "non destructive testing",
            "back propagation",
            "point spread function"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Bruce W. Drinkwater",
                "org": "Department of Mechanical Engineering, University Walk, University of Bristol, Bristol BS8 1TR, UK"
            },
            {
                "name": "Paul D. Wilcox",
                "org": "Department of Mechanical Engineering, University Walk, University of Bristol, Bristol BS8 1TR, UK"
            }
        ],
        "venue": "NDT and E International",
        "year": 2011
    },
    "sM6B7J0x": {
        "id": "sM6B7J0x",
        "title": "Effect of roughness on imaging and characterizing rough crack-like defect using ultrasonic arrays",
        "abstract": "",
        "keywords": [
            "roughness"
        ],
        "authors": [
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "bruce w drinkwater",
                "org": "university of bristol"
            },
            {
                "name": "paul d wilcox",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2012
    },
    "XfA9QTJN": {
        "id": "XfA9QTJN",
        "title": "Comparison of ultrasonic array imaging algorithms for nondestructive evaluation.",
        "abstract": "Ultrasonic array imaging algorithms have been widely used and developed in nondestructive evaluation in the last 10 years. In this paper, three imaging algorithms [total focusing method (TFM), phase-coherent imaging (PCI), and spatial compounding imaging (SCI)] are compared through both simulation and experimental measurements. In the simulation, array data sets were generated using a hybrid forward model containing a single defect among a multitude of randomly distributed point scatterers to represent backscatter from material microstructure. The number of point scatterers per unit area and their scattering amplitude were optimized to reduce computation cost. The SNR of the final images and their resolution were used to indicate the quality of the different imaging algorithms. The images of different types of defects (point reflectors and planar cracks) were used to investigate the robustness of the imaging algorithms. It is shown that PCI can yield higher image resolution and higher SNR for defects in material with weak backscatter than TFM, but that the images of cracks are distorted. Overall, TFM is the most robust algorithm across a range of different types of defects. It is also shown that the detection limit of all three imaging algorithms is almost equal for weakly scattering defects.",
        "keywords": [
            "point scatterers per unit area",
            "total focusing method",
            "nondestructive evaluation",
            "ultrasonic imaging",
            "hybrid forward model",
            "ultrasonic arrays",
            "ultrasonic array imaging algorithm",
            "randomly distributed point scatterer",
            "ultrasonic materials testing",
            "spatial compounding imaging",
            "phase coherent imaging",
            "scattering amplitude",
            "microstructure",
            "backscatter"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Dept. of Mech. Eng., Univ. of Bristol, Bristol, UK|c|"
            },
            {
                "name": "bruce w drinkwater",
                "org": "university of bristol"
            },
            {
                "name": "paul d wilcox",
                "org": ""
            }
        ],
        "venue": "IEEE transactions on ultrasonics, ferroelectrics, and frequency control",
        "year": 2013
    },
    "l8TL43HV": {
        "id": "l8TL43HV",
        "title": "Efficient computation of delay law for imaging structure with a complex surface",
        "abstract": "",
        "keywords": [
            "interpolation",
            "linear interpolation",
            "inspection",
            "surface structure",
            "imaging",
            "fermat s principle",
            "propagation delay",
            "grid search",
            "acoustics"
        ],
        "authors": [
            {
                "name": "jie zhang",
                "org": "university of bristol"
            },
            {
                "name": "bruce w drinkwater",
                "org": "university of bristol"
            },
            {
                "name": "paul d wilcox",
                "org": "university of bristol"
            }
        ],
        "venue": "",
        "year": 2013
    },
    "EpgcE7Iv": {
        "id": "EpgcE7Iv",
        "title": "Ultrasonic array imaging in nondestructive evaluation: total focusing method with using circular coherence factor",
        "abstract": "",
        "keywords": [
            "backscatter",
            "distortion",
            "algorithms",
            "nondestructive evaluation",
            "signal to noise ratio",
            "image resolution",
            "scattering"
        ],
        "authors": [
            {
                "name": "jie zhang",
                "org": "university of bristol"
            },
            {
                "name": "bruce w drinkwater",
                "org": "university of bristol"
            },
            {
                "name": "paul d wilcox",
                "org": "university of bristol"
            }
        ],
        "venue": "",
        "year": 2013
    },
    "4yViO2aJ": {
        "id": "4yViO2aJ",
        "title": "Ultrasonic array imaging in nondestructive evaluation",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "bruce w drinkwater",
                "org": "university of bristol"
            },
            {
                "name": "paul d wilcox",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2013
    },
    "DrSgOmfA": {
        "id": "DrSgOmfA",
        "title": "Novel ray-tracing algorithms in NDE",
        "abstract": "",
        "keywords": [
            "anisotropy",
            "networks",
            "orientation",
            "metals",
            "propagation",
            "shortest path algorithm"
        ],
        "authors": [
            {
                "name": "oliver nowers",
                "org": ""
            },
            {
                "name": "david j duxbury",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "bruce w drinkwater",
                "org": "university of bristol"
            }
        ],
        "venue": "Ndt & E International",
        "year": 2014
    },
    "thGpIUjJ": {
        "id": "thGpIUjJ",
        "title": "Novel ray-tracing algorithms in NDE: Application of Dijkstra and A ⁎ algorithms to the inspection of an anisotropic weld",
        "abstract": "",
        "keywords": [
            "anisotropy"
        ],
        "authors": [
            {
                "name": "oliver nowers",
                "org": ""
            },
            {
                "name": "david j duxbury",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "bruce w drinkwater",
                "org": ""
            }
        ],
        "venue": "Ndt & E International",
        "year": 2014
    },
    "kmg1tFfH": {
        "id": "kmg1tFfH",
        "title": "Measurement of the Ultrasonic Scattering Matrices of Near-Surface Defects Using Ultrasonic Arrays",
        "abstract": "AbstractUltrasonic arrays have been widely used and developed for defect detection and characterisation over the last 10 years. In this paper, the question of how to inspect and characterise near-surface defects that are small with respect to wavelength is addressed. The challenge is to overcome the effect of the proximity of these scattered signals to high-amplitude signals reflected from structural features, such as planar surfaces. Here, a method is proposed to extract the scattered signals from a near-surface defect which overlap with signals from a structural feature in both the time and frequency domains. The extracted signals are then used to generate a scattering coefficient matrix, from which it is possible to characterise the defect. In the proposed method, the location of the defect is first approximately identified from an image. The arrival time difference between the signals from the defect and the nearby planar surfaces for each combination of transmitter and receiver array elements is then...",
        "keywords": [],
        "authors": [
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "peng yu",
                "org": ""
            },
            {
                "name": "tie gang",
                "org": ""
            }
        ],
        "venue": "Nondestructive Testing and Evaluation",
        "year": 2015
    },
    "RE7jtOKS": {
        "id": "RE7jtOKS",
        "title": "Investigation of ultrasonic scattering matrix extraction of a surface defect using ultrasonic arrays",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "peng yu",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "tie gang",
                "org": ""
            },
            {
                "name": "bruce w drinkwater",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2015
    },
    "DeGVIz7Y": {
        "id": "DeGVIz7Y",
        "title": "Comparison of ultrasonic image features with echodynamic curves for defect classification and characterization",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "sam wedge",
                "org": ""
            },
            {
                "name": "allan rogerson",
                "org": ""
            },
            {
                "name": "bruce w drinkwater",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2015
    },
    "MDh57P4R": {
        "id": "MDh57P4R",
        "title": "On the radiation force fields of fractional-order acoustic vortices",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "zhenyu hong",
                "org": "university of bristol"
            },
            {
                "name": "jie zhang",
                "org": "university of bristol"
            },
            {
                "name": "bruce w drinkwater",
                "org": "university of bristol"
            }
        ],
        "venue": "EPL",
        "year": 2015
    },
    "5NBCDhj0": {
        "id": "5NBCDhj0",
        "title": "Observation of Orbital Angular Momentum Transfer from Bessel-Shaped Acoustic Vortices to Diphasic Liquid-Microparticle Mixtures",
        "abstract": "We observe distinct regimes of orbital angular momentum (OAM) transfer from two-dimensional Bessel-shaped acoustic vortices to matter. In a homogeneous diphasic mixture of microparticles and water, slow swirling about the vortex axis is seen. This effect is driven by the absorption of OAM across the mixture, the motion following the OAM density distribution. Larger particles are formed into clusters by the acoustic radiation force, making the mixture nonhomogeneous. Here, the OAM transfer to the microparticle clusters dominates and they spin at high speeds entraining the surrounding fluid. ",
        "keywords": [
            "rotational motion"
        ],
        "authors": [
            {
                "name": "zhenyu hong",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "bruce w drinkwater",
                "org": "university of bristol"
            }
        ],
        "venue": "Physical review letters",
        "year": 2015
    },
    "EpBANUdj": {
        "id": "EpBANUdj",
        "title": "The Development of Chinese Dyestuff Industry:New Features & New Circumstances to Face",
        "abstract": "The development of the dyestuff industry in China presents new features:constant emergence of new dyestuffs, sustained growth of export and shifting of production centers. At the same time,the industry also faces new situations: increasing import and prices,stronger competition among international players,higher “green” barriers and energy shortage.While analyzing these phenomena,the article also points out some problems that demand particular attention during the development of the Chinese dyestuff industry.",
        "keywords": [
            "new circumstance",
            "market situation",
            "new features",
            "dyestuff industry"
        ],
        "authors": [
            {
                "name": "Zhang Jie",
                "org": "Shanghai Dyestuffs Co.,Ltd."
            }
        ],
        "venue": "China Textile Leader",
        "year": 2005
    },
    "Rm3IgWW8": {
        "id": "Rm3IgWW8",
        "title": "The development motions of the textile auxiliaries in the world",
        "abstract": "The development motions of the textile auxiliaries in the world are described,and the status quo of market and recent features of the developm ent are pointed out: the West European auxiliaries keep on occupying the predomi nant position in the world,the strength of setting\"technical barriers\",\"trading barriers\"and \"green barriers\"have been further reinforced,and the development of the new text.auxiliaries has been put onto the marked position.",
        "keywords": [
            "textile auxiliaries",
            "new features",
            "market status quo",
            "the world",
            "developm entmotions"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Shanghai Dyestuff Co.,Ltd.,Shanghai ,China"
            }
        ],
        "venue": "Textile Auxiliaries",
        "year": 2005
    },
    "Wv3gp1Tj": {
        "id": "Wv3gp1Tj",
        "title": "New developing trends for dyestuff industry at home and abroad",
        "abstract": "In this article, the new developing trends for the dyestuff industry both at home and abroad were introduced. The market trends and new developing characteristics of the dyestuffs at abroad is stable trends of combination of dyes manufacturers, further establish our country's position of the center of dyes manufacturing and supplying in the world, further strengthen the ”technical barrier” and ”trade barrier”, focus on new dyes developing, constantly meet the new needs of textile industry. The new development of our dyes industry features brisk market, new products, increased export, new base and strong development etc.",
        "keywords": [
            "external",
            "developing",
            "internal",
            "dyestuff industry"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Shanghai Dyestuffs Co., Ltd., Shanghai , China "
            }
        ],
        "venue": "Dyeing and Finishing",
        "year": 2005
    },
    "R5Y3p2ix": {
        "id": "R5Y3p2ix",
        "title": "EU Directive on Restricted Use of APEO and Its Effect on China's Textile Auxiliaries Industry",
        "abstract": "According to EU Directive 2003/53/EG,Europe strictly restricts the use of alkyl phenol ethoxylates (APEO) from January 17,2005.The article introduces the harm of APEO,and the production,use and testing of APEO in China.It also lists some APEO-substitute products and calls on making greater efforts to the R & D of substitute products.",
        "keywords": [
            "toxicity",
            "substitute product",
            "testing",
            "APEO"
        ],
        "authors": [
            {
                "name": "Zhang Jie",
                "org": "Shanghai Dyestuffs Co.,Ltd."
            }
        ],
        "venue": "China Textile Leader",
        "year": 2005
    },
    "LeKbDy2b": {
        "id": "LeKbDy2b",
        "title": "Situation of market of textiles and dyestuffs after canceling quota",
        "abstract": "The situation of the textile  market and the dyestuff  market of the whole world, especially China, India, Korea, Pakistan and so on, after canceling quota was introduced in this article, and the key points, which the dyestuff enterprises in our country should reply, were pointed out.",
        "keywords": [
            "dye",
            "textiles",
            "after canceling quota",
            "international market"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Shanghai Dyestuffs Co., Ltd., Shanghai , China"
            }
        ],
        "venue": "Dyeing and Finishing",
        "year": 2005
    },
    "uT4JXvIx": {
        "id": "uT4JXvIx",
        "title": "Reason Analysis in Respect to Several Colour Fastnesses of Fabrics Dyed by Reactive Dyestuffs and Improving Technologies",
        "abstract": "The several colour fastnesses of the fabrics dyed by reactive dyestuffs,for example fastness to light,fastness to light-perspiration,fastness to wet rubbing,fastness to chlorine etc,are one of the main problems,which exist at present in reactive dyestuffs.The reason to exert this problem and the location to be affected in the reactive dyestuff were analyzed in this paper.Also,the improving technologies were pointed out.",
        "keywords": [
            "reactive dyestuff",
            "colour fastnesses",
            "reason analysis",
            "improving technology"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": ""
            },
            {
                "name": "XIAO Qin",
                "org": ""
            }
        ],
        "venue": "Dyestuffs and Coloration",
        "year": 2006
    },
    "FDIprvxf": {
        "id": "FDIprvxf",
        "title": "Development of disperse dyes in China",
        "abstract": "In this paper,the present situation of China′s disperse dyes in recent years was introduced.The research and development of disperse dyes quality and varieties in China during the eleventh-five years were described.This will greatly upgrade the levels concerning technology and production and quality of domestic disperse dyes.",
        "keywords": [
            "disperse dye",
            "dyeing",
            "develop"
        ],
        "authors": [
            {
                "name": "XIAO Qin",
                "org": "Shanghai Dyestuffs Co.,Ltd.,Shanghai ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Shanghai Dyestuffs Co.,Ltd.,Shanghai ,China"
            }
        ],
        "venue": "Dyeing & Finishing",
        "year": 2006
    },
    "2Njzw76M": {
        "id": "2Njzw76M",
        "title": "Ecological demands on textile finish",
        "abstract": "Finishing is a key step to enhance the added value of textiles.Ecological finishing agents must meet the following demands,such as highly biodegradable,low toxicity,low or free formaldehyde,and so on.Finishing agents which are widely applied in practice are analyzed,including anti-crease agents,softeners,flame retardants,oil and water repellents,antibacterial and odor agents,anti-moth agents and anti-mildew agents.The restricted and prohibited agents,as well as their substitutes are put forward.",
        "keywords": [
            "finish",
            "finishing agent",
            "textiles",
            "ecology"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Shanghai Dyestuffs Co.,Ltd.,Shanghai ,China"
            }
        ],
        "venue": "Dyeing & Finishing",
        "year": 2006
    },
    "9F0nZeP9": {
        "id": "9F0nZeP9",
        "title": "The market situation and developing trend of the environment-friendly dyes and textile-used auxiliaries",
        "abstract": "This paper reviews the present situation and developing trend of the environment-friendly dyes and textile-used auxiliaries, introduces the 10 criteria for distinguishing the environment-friendly dyes and 8 criteria for distinguishing the environment-friendly textile-used auxiliaries, describes in detail the environment-friendly dyes including reactive dye, disperse dye, acid dye and the new type environment-friendly textile-used auxiliaries including pretreatment agent, dyeing and printing used agent and post treatment agent. This paper provides a reference for the dyeing and printing enterprises in selecting the environment-friendly dyes and textile-used auxiliaries.",
        "keywords": [],
        "authors": [
            {
                "name": "Zhang Jie",
                "org": ""
            },
            {
                "name": "Zhang Xiao-qin",
                "org": ""
            }
        ],
        "venue": "Knitting Industries",
        "year": 2006
    },
    "j0lPoiHX": {
        "id": "j0lPoiHX",
        "title": "Analysis in Respect to the Problems of Colour Fastnesses of Fabrics Dyed with Disperse Dyes and Improvement on Technologies",
        "abstract": "In recent years the problems of the colour fastnesses i.e.the discolouration and the falling colour and the colour spot and the colour staining of the polyester fabrics are one of the main problems,which exist in the disperse dyes.The reasons to exert these problems and the improvement on the technologies are analyzed in the article.",
        "keywords": [
            "colour spot",
            "colour fastnesses",
            "polyester fabric",
            "analysis of reasons",
            "disperse dyes",
            "improvement on technologies",
            "colour staining"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Shanghai Dyestuff Co.ltd,Shanghai "
            },
            {
                "name": "XIAO qin",
                "org": "Shanghai Dyestuff Co.ltd,Shanghai "
            }
        ],
        "venue": "Dyestuffs and Coloration",
        "year": 2006
    },
    "U1cXToBf": {
        "id": "U1cXToBf",
        "title": "Safe and ecological requirements to textiles",
        "abstract": "By means of the deepgoing comprehension to the national standard GB 18401—2003 and professional standard SN/T 1649—2005, as well as three types of eco labels on the international market, the safe and ecological requirements to textiles both at home and abroad are described .The distance between domestic textile standards and the requirements of the textiles on the international market was pointed out .The countermeasures were put forward.",
        "keywords": [
            "safety",
            "measure",
            "dyeing and finishing",
            "textiles",
            "ecology"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Shanghai Dyestuffs Co., Ltd., Shanghai , China"
            }
        ],
        "venue": "Dyeing & Finishing",
        "year": 2006
    },
    "l0OMCvUK": {
        "id": "l0OMCvUK",
        "title": "Developing Trends for Dyestuff Industry in the World",
        "abstract": "To introduce developing trends for the dyestuff industry in the world.To indicate the market trend and the new developing characteristics of the dyestuffs in the world.The characteristics of newly-developed dyestuffs were also described.",
        "keywords": [
            "development",
            "characteristics",
            "dyestuffs"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Shanghai Dyestuff Co.,Ltd,Shanghai ,China"
            }
        ],
        "venue": "Chemical Techno-Economics",
        "year": 2006
    },
    "li6Yd4R2": {
        "id": "li6Yd4R2",
        "title": "Current status of banned and restricted textile chemicals and countermeasures after canceling quota",
        "abstract": "The status quo of banned and restricted textile chemicals and countermeasures after canceling quota was reviewed.Some banned and restricted textile dyeing and additives were introduced.The challenge from the actualization of EU's REACH upon China was analyzed,and some countermeasures were given.",
        "keywords": [
            "post-quota-offering period",
            "restricted",
            "banned",
            "textile chemicals"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Shanghai Dyeing Co.,Ltd.,Shanghai ,China"
            },
            {
                "name": "ZHANG Xiao-qin",
                "org": "Shanghai Dyeing Co.,Ltd.,Shanghai ,China"
            }
        ],
        "venue": "Modern Chemical Industry",
        "year": 2006
    },
    "EFnAbuPr": {
        "id": "EFnAbuPr",
        "title": "The market situation and developing trend of the environment-friendly dyes and textile auxiliaries(Part I)",
        "abstract": "This paper reviews the present situation and development of the environment-friendly dyes and textile auxiliaries, introduces ten criteria for the environment-friendly dyes and eight criteria for the environment-friendly textile auxiliaries and introduces in detail he present situation and development of the environment-friendly dyes (including reactive dye, disperse dye and acid dyes) and the new type of the environment-friendly textile auxiliaries (including pretreatment agent, the auxiliaries for dyeing and printing and post treatment agent), which provides a reference for the printing and dyeing enterprises to select and use the environment-friendly dyes and textile auxiliaries.",
        "keywords": [],
        "authors": [
            {
                "name": "Zhang Jie",
                "org": ""
            },
            {
                "name": "Zhang Xiao-qin",
                "org": ""
            }
        ],
        "venue": "Knitting Industries",
        "year": 2006
    },
    "1mkzjXmi": {
        "id": "1mkzjXmi",
        "title": "Development of textiles RFT dyeing and its related chemicals",
        "abstract": "The REACH proposal published by EU will exert a great influence on the chemical industries and their downstream industries of all over the world.In order to reply good at repartee,the printing and dyeing industries of all countries are making great efforts to raise production efficiencies and to reduce production costs.The recent development of RFT dyeing technologies of textiles and related textile chemicals were described in this article,including Dyexact XP system for polyester,RFT dyeing for polyester/cotton blends,lnnovat dyeing system for cotton and so on.They are an important countermeasure to reply good at repartee to the REACH regulation published by EU.",
        "keywords": [
            "dyes and chemicals",
            "dyeing",
            "right-first-time",
            "textiles",
            "develop"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Shanghai Dyestuffs Co.,Ltd.,Shanghai ,China"
            }
        ],
        "venue": "Dyeing & Finishing",
        "year": 2006
    },
    "yuUWbNeY": {
        "id": "yuUWbNeY",
        "title": "Developing Trends of the World Dyestuff Industry",
        "abstract": "The developing trends of the global dyestuffindustry are introduced in this article, and the trends of theworld dyestuff market and new characteristics of developmentare also discussed. According to the article, the reorganizationprocess of dyestuff enterprises has come into a smooth state,China has further consolidated its position as the dyestuffproduction and supply center in the world, both òtechnicalbarriersó and òtrade barriersó on the world market havebecome higher than before and developing new dyestuffs hasbeen put on a more important place. The article also introducesthe characteristics of some new dyestuffs that are developed tosuit the needs of textile industry for higher fastness and higherperformance and to suit the dyeing of new fibers as well asnew printing and dyeing technologies.",
        "keywords": [
            "disperse dye",
            "technical barrier.",
            "reactive dye",
            "new dyestuff",
            "dyestuff industry"
        ],
        "authors": [
            {
                "name": "Xiao Qin",
                "org": ""
            },
            {
                "name": "Zhang Jie",
                "org": ""
            }
        ],
        "venue": "China Textile Leader",
        "year": 2006
    },
    "IgORxPju": {
        "id": "IgORxPju",
        "title": "New Developing Characteristics of Dyestuff Industry in Our Country and New Grim Situation to Face",
        "abstract": "Four new developing characteristics through the analysis of the dyestuff industry in our country after getting into the new century were introduced in this article.The new grim situation,that faces to develop further the dyestuff industry in our country,was pointed out from the four respects.",
        "keywords": [
            "dyestuff industry in our country",
            "new developing characteristics",
            "new grim situation"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Shanghai Dyestuff Co.,Ltd,Shanghai "
            }
        ],
        "venue": "Dyestuffs and Coloration",
        "year": 2007
    },
    "3dpM29P6": {
        "id": "3dpM29P6",
        "title": "Technological Progress of Reactive Dye for Cellulose Fibre",
        "abstract": "The reactive dyes for cellulose fibre is currently the most important reactive dye.The technological progress of the reactive dyes for cellulose fibre was in this article described from six respects,that is the technology to raise the fixation rate,the technology to raise the exhaustion rate,the technology to raise the colour fastness,the technology to raise the levelness and the reproducibility,the development of the reactive dyes for low salt dyeing and the technology to raise the jet-black degree of the black reactive dyes.Also,the technological progress of the reactive dyeing was described.They showed clearly the direction for the faster development of the reactive dyes for cellulose fibre.",
        "keywords": [
            "cellulose fibre",
            "reactive dye",
            "technological progress"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Shanghai Dystuff Co.Ltd.,Shanghai "
            }
        ],
        "venue": "Dyestuffs and Coloration",
        "year": 2007
    },
    "IVeyFzkr": {
        "id": "IVeyFzkr",
        "title": "The development of Chinese dyestuff industry:new features and new circumstance",
        "abstract": "This paper covers four characteristics of Chinese dyestuff industry,such as industry restructuring,enlargement of production bases,market active,new varieties emerging and export increasing.Chinese dyestuff industry also face some new circumstance of high demand on energy saving and low discharge,REACH implementation,adjustment of export rebate policy,emergency on new products and technology innovation.",
        "keywords": [
            "dye industry",
            "development",
            "domestic"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Shanghai Dyestuffs Co.,Ltd.,Shanghai ,China"
            }
        ],
        "venue": "Dyeing & Finishing",
        "year": 2007
    },
    "18686u63": {
        "id": "18686u63",
        "title": "Ecological problems of chemicals and their substitutes for textile pretreatment",
        "abstract": "This paper covers the ecological requirements on chemicals for textile pretreatment.Ecological problems of available chemicals are analyzed,such as warp sizing agents,desizing agents and assistants,bleaching agents,scouring agents and detergents,and so on.The prohibited chemicals and their substitutes for textile pretreatment are put forward.",
        "keywords": [
            "pretreatment",
            "assistant",
            "textiles",
            "ecology"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Shanghai Dyestuffs Co.,Ltd.,Shanghai ,China"
            }
        ],
        "venue": "Dyeing & Finishing",
        "year": 2007
    },
    "BXQPAMzm": {
        "id": "BXQPAMzm",
        "title": "Performance/price ratio of Chinese dyestuffs and rational selection and use(Ⅰ)",
        "abstract": "From the aspects of shade,application method,dye depth,environment and ecology requirements,as well as price,the performance/price ratio and selective standard of Chinese dyestuffs,especially reactive dyestuffs and disperse dyestuffs,were described in this article.The points for attention to be correctly selected and rationally used were pointed out.",
        "keywords": [
            "price",
            "property",
            "selectivity",
            "dyes"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Shanghai Dyestuffs Co.,Ltd.,Shanghai ,China"
            }
        ],
        "venue": "Dyeing & Finishing",
        "year": 2008
    },
    "ydS9k84w": {
        "id": "ydS9k84w",
        "title": "Review and Prospect of China Dyestuff Industry for 30 Years of Reform and Opening",
        "abstract": "Development characteristics of China dyestuff industry during 30 years of reform and opening-up were described,including mechanism transition,position of private enterprises,active market,both production and marketing thriving,higher market share of environmental friendly products,fully developed product varieties,and so on.Issues including energy saving and emission reduction,environment protection and macroeconomy regulation,which dyestuff industry were confronted with currently were discussed.It was pointed out that trends of leading dyestuff industry to a specializational & powerful way relied on innovations of products,processing,management and service.",
        "keywords": [
            "development",
            "prospect",
            "30 years of reform and opening",
            "China dyestuff industry",
            "dyestuff",
            "industry",
            "review"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Shanghai Dyestuffs Co.,Ltd.,Shanghai ,China"
            }
        ],
        "venue": "Dyeing & Finishing",
        "year": 2008
    },
    "4aXqDqLI": {
        "id": "4aXqDqLI",
        "title": "Focus on prohibited and limited chemicals for textiles (I)",
        "abstract": "This paper covers the problems concerned about prohibited and limited chemicals for textiles, most of them are cancerogenic aromatic amines, nongenotoxicity, heavy metal content, environmental hormone in dyestuffs, basic safety requirements on chemicals for textiles, as well as prohibited APEO, PFOS and PFOA. Corresponding alternatives are launched.",
        "keywords": [
            "assistant",
            "dyeing and finishing",
            "ecological textiles"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Shanghai Dyestuffs Co., Ltd., Shanghai , China"
            }
        ],
        "venue": "Dyeing & Finishing",
        "year": 2008
    },
    "UETe3vnl": {
        "id": "UETe3vnl",
        "title": "Preparation for pre-registration and registration of REACH",
        "abstract": "The REACH law and regulation issued by EU will put into effect on June 1st, 2008. The challenges of the REACH on China dyestuff industry and textile industry were further analyzed in aspects of exportation, importation, competitive power, creation of new products, and so on. It was pointed out that enterprises should make preparations for pre-registration and registration of the REACH at present.",
        "keywords": [
            "REACH",
            "dyeing and finishing industry",
            "registration",
            "dyestuff industry"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Shanghai Dyestuffs Co., Ltd., Shanghai , China"
            }
        ],
        "venue": "Dyeing & Finishing",
        "year": 2008
    },
    "rTpp2cv1": {
        "id": "rTpp2cv1",
        "title": "The textile fluoro-surfactants on the POP_S list and its novel substitute",
        "abstract": "Fluoro-surfactant is the key component of multi-functional finishing agent of fabric.Two kinds of harmful fluoro-surfactants,perfluorooctane sulphonate and its sulfonylate(PFOS) and perfluorooctanoic acid(PFOA),whose dosage was large on textiles,were expatiated.Because they have permanent environmental sta-bility and high bioaccmulation property,they have be placed on the POPS(permanent organic pollutants) list and be forbidden.At the same time,novel substitutes were discussed: perfluorohexane sulphonate or its sulfonylate(PFHS),perfluorohexylic acid(PFHA),perfluorobutane sulphonate or its sulfonylate(PFBS),compound fluoro fin-ishing agent,acrylic fluorocarbon ester resin,polytetrafluoroethylene and nano finishing agent etc.",
        "keywords": [
            "novel substitute",
            "textile fluoro-surfactant",
            "multi-functional finishing agent",
            "U.N.POPS list",
            "PFOA",
            "PFOS"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Shanghai Dyestuffs Co.,Ltd.,Shanghai ,China"
            },
            {
                "name": "ZHANG Xiao-qin",
                "org": "Shanghai Dyestuffs Co.,Ltd.,Shanghai ,China"
            }
        ],
        "venue": "Textile Auxiliaries",
        "year": 2009
    },
    "nI0OOgWD": {
        "id": "nI0OOgWD",
        "title": "New Type of Substitutes of Prohibited Fluorine-contained Surfactants and Finshing Agents",
        "abstract": "The fluorine-contained surfactant is an important component of the multifunctional textile finishing agent.The two harmful fluorine-contained surfactants-PFOS and PFOA,which were largely used on textiles,were in this article described.Because of they possess the permanent stability in environment and the high bioaccumulation,they would be placed on the detailed list of POPs by the United Nations and their use would be prohibited.Besides,their newest substitutes were discussed through six ways.",
        "keywords": [
            "detailed list of POPs of the United Nations",
            "PFOA",
            "PFOS",
            "substitutes",
            "fluorine-containted surfactants used for textiles",
            "multifunctional textile finishing agents"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Shanghai Dyestuff Go.Ltd.,Shanghai ,China"
            },
            {
                "name": "XIAO Qin",
                "org": "Shanghai Dyestuff Go.Ltd.,Shanghai ,China"
            }
        ],
        "venue": "Dyestuffs and Coloration",
        "year": 2009
    },
    "0R5rdg0V": {
        "id": "0R5rdg0V",
        "title": "Safety Requirement of Textile Auxiliaries and New Developments",
        "abstract": "The safety requirement of textile auxiliaries is a necessery index of the auxiliaries,those are chosen and used by the textile industry.The basic safety requirement of textile auxiliaries at present was described in this article.And the new developments of the prohibited and restricted chemical substances in textile auxiliaries were further expounded from the point of the developing trend to the safety requirement of textiles on the market.",
        "keywords": [
            "textile auxiliaries",
            "basic safety requirement",
            "new developments"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Shang hai Dyestuff Co.Ltd.,Shang hai ,China"
            },
            {
                "name": "XIAO Qin",
                "org": "Shang hai Dyestuff Co.Ltd.,Shang hai ,China"
            }
        ],
        "venue": "Dyestuffs and Coloration",
        "year": 2009
    },
    "qsuATIwv": {
        "id": "qsuATIwv",
        "title": "The ecology problems of coating agent of textiles and its resolution",
        "abstract": "Textile coating is an important finish technology.The ecology demands of coating agent was stated and the ecology problems of coating agent(polyacrylate,polyurethane and polyvinyl chloride) were analyzed,and the resolution and their substitutes were pointed out.At the same time,the ecology problems of additives in the coating agents and its resolution were introduced.The substitutes were pointed out,respectively:(1) flame re-tardant(swelling type of bicyclic cage type phosphate derivative,organic boric base,novel silicon base,boric-ni-trogen synergistic flame retardant system,and boric-silicon synergistic flame retardant system,complex of or-ganic compound and inorganic nitrogen salt,and nitrogen derivative of alkyl phosphoric acid);(2) water proofing a-gent(modified silicone polyemulsion,acrylic fluorocarbon ester resin,fluoro stain-removing agent with hydrophilic chain,weak cationic fluoride dispersion);(3) bactericide(inorganic compound,quaternary ammonium salt,carbami-dine,natural compound);(4) crosslinking agent must be those which would not contain or release formaldehyde,or low formaldehyde crosslinking agent to accord with the standard could be used.",
        "keywords": [
            "ecology problem",
            "coating agent",
            "textiles",
            "resolution"
        ],
        "authors": [
            {
                "name": "ZHANG Xiao-qin",
                "org": "Shanghai Dyestuffs Co.,Ltd.,Shanghai ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Shanghai Dyestuffs Co.,Ltd.,Shanghai ,China"
            }
        ],
        "venue": "Textile Auxiliaries",
        "year": 2009
    },
    "xenGOKBg": {
        "id": "xenGOKBg",
        "title": "Development and application of ecological dyestuffs",
        "abstract": "Development and application of new dyestuffs for energy saving and pollutant reduction process were discussed,including dyes used for cotton fabric except for reactive dyes,such as direct dyes suitable for high-performance dyeing,one-bath-one-step dyeing and high dye exhaustion and wet fastness dyeing;vat dyes suitable for Innovat dyeing,electrochemical reduction dyeing and high chlorine fastness dyeing;sulfur dyes suitable for PAD-OX dyeing,low-sodium sulfide dyeing and non-reduction dyeing;cationic dyes with high steam-resistance and suitable for low-staining dyeing and eco-friendly pigment printing paste.",
        "keywords": [
            "dyeing and finishing",
            "energy-saving and emission reduction",
            "environmental protection",
            "dyes"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Shanghai Dyestuff Co.,Ltd.,Shanghai ,China"
            }
        ],
        "venue": "Dyeing & Finishing",
        "year": 2009
    },
    "Bvd0jqpu": {
        "id": "Bvd0jqpu",
        "title": "Development and application of eco-friendly dyes for wool",
        "abstract": "Dyestuffs and auxiliaries used for wool in energy-saving and emission reduction processes and their applications are expounded,including a new type of acid dyes,reactive dyes,metal complex dyes with high exhaustion and high color fastness for energy-saving and emission reduction processes such as one-bath and one-step dyeing,low temperature dyeing of wool,right-first-time dyeing and rapid dyeing.",
        "keywords": [
            "wool fabric",
            "polyamide fiber",
            "dyeing and finishing",
            "energy-saving and emission reduction",
            "dyes"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Shanghai Dyestuff Co.,Ltd.,Shanghai ,China"
            }
        ],
        "venue": "Dyeing & Finishing",
        "year": 2009
    },
    "8CtVxVyV": {
        "id": "8CtVxVyV",
        "title": "Development and application of novel textile chemicals meeting the demands of low carbon economy",
        "abstract": "At present,low-carbon economy is elevated to an unprecedented level.In order to achieve the revitalization of dyeing and printing industry in China,novel dyeing and finishing techniques adapting to low carbon economy are developed.Variety of novel reactive dyes,disperse dyes and assistants developed for meeting the demands of low carbon economy were reviewed,which present energy saving,emission and pollution reduction effect,increase the added value of product,and play an important role in the revitalization of dyeing and printing industry.Meanwhile,laws,regulation and standard on ecological textiles are obeyed in domestic and foreign markets.",
        "keywords": [
            "application",
            "low carbon economy",
            "development",
            "dyes and assistants",
            "novel textile chemicals"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Shanghai Dyestuff Co.,Ltd.,Shanghai ,China"
            },
            {
                "name": "ZHANG Xiao-qin",
                "org": "Shanghai Dyestuff Co.,Ltd.,Shanghai ,China"
            }
        ],
        "venue": "Textile Auxiliaries",
        "year": 2010
    },
    "AXz8jkNe": {
        "id": "AXz8jkNe",
        "title": "New development and application of energy-saving and emission reduction type pretreatment agents",
        "abstract": "Energy-saving and emission reduction and environment protection are the basic national policy of China's economic development.In order to achieve the revitalization of the industry,printing and dyeing industry of China has developed or is developing new energy-saving and emission reduction technique and technology.Energy-saving and emission reduction type pretreatment agents and the application were introduced,including low temperature agents,high performance agents,multi-functional agents and specific pretreatment agents,which play important basic role in the revitalization of the industry.",
        "keywords": [
            "application",
            "pretreatment agents",
            "energy-saving and emission reduction",
            "new development"
        ],
        "authors": [
            {
                "name": "ZHANG Xiao-qin",
                "org": "Shanghai Dyestuff Co.,Ltd.,Shanghai ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Shanghai Dyestuff Co.,Ltd.,Shanghai ,China"
            }
        ],
        "venue": "Textile Auxiliaries",
        "year": 2010
    },
    "18QyM4ed": {
        "id": "18QyM4ed",
        "title": "New textile chemicals applied in right-first-time dyeing of textiles",
        "abstract": "The current low-carbon economy is referred to an unprecedented level.Right-first-time dyeing of textiles is an important way of developing low-carbon economy.The new textile chemicals,including textile assistants(pretreatment and dyeing assistants) and dyes(new reactive dyes and disperse dyes etc.) applied in right-first-time dyeing of textiles were reviewed.They play an important role in promoting low-carbon economy and revitalizing printing and dyeing industry.",
        "keywords": [
            "textiles",
            "new textile chemicals(assistants and dyes)",
            "right-first-time dyeing",
            "low-carbon economy"
        ],
        "authors": [
            {
                "name": "ZHANG Xiao-qin",
                "org": "Shanghai Dyestuffs Co.,Ltd.,Shanghai ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Shanghai Dyestuffs Co.,Ltd.,Shanghai ,China"
            }
        ],
        "venue": "Textile Auxiliaries",
        "year": 2011
    },
    "zLS4x2Ir": {
        "id": "zLS4x2Ir",
        "title": "Research and development of substitutes for substances of very high concern(Ⅰ)",
        "abstract": "A substance of very high concern(SVHC) is a chemical substance(or part of a group of chemical substances) for which it has been proposed that the use within the European Union be subject to authorisation under the REACH Regulation.Substitutes and substitution plan must be put forward to apply for an authorization.The research and development of substitutes for 49 chemicals in the SVHC candidates list put forward by ECHA(European Chemicals Agency) are introduced.",
        "keywords": [
            "REACH",
            "substances of very high concern(SVHC)",
            "laws and regulations",
            "dyeing and finishing"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Shanghai Dyestuffs Co.,Ltd.,Shanghai ,China"
            }
        ],
        "venue": "Dyeing & Finishing",
        "year": 2011
    },
    "h6C7U8Vk": {
        "id": "h6C7U8Vk",
        "title": "Analysis of consultation characteristics for elderly patients in the department of psychosomatic medicine in Hospital of TCM",
        "abstract": "Objective To analyze the characteristics of consultatioti for elderly patients in the department of psychosomatic medicine of our hospital.Methods 157 elderly patients accepting consultation in the department of psychosomatic medicine were analyzed.The aspects of analysis included the departments and reasons for consultations,and diagnoses after consultation.Results The most common diseases were cardiovascular,cerebrovascular and digestive diseases in elderly patients complicated with mental disorders;the most common reason for consultation is associated with sleep disorders;the most common diagnoses of consultation is the mixed anxiety-depressive disorder;high risk of delirium was increased in elderly patients.Conclusion Diagnosis and treatment of psychiatric-related diseases provided by the department of psychosomatic medicine for many patients,at the same time,Consultation in Dept.of Psychiatry is also necessary.Therefore, the department of psychosomatic medicine as a bridge can strengthen the link providing comprehensive services for patients.",
        "keywords": [
            "delirium",
            "anxiety",
            "psychosomatic medicine",
            "mental disorders",
            "referral and consultation"
        ],
        "authors": [
            {
                "name": "PEI Yin",
                "org": "Department of Psychosomatic Medicine,Beijing Hospital of Traditional Chinese Medicine, Capital Medical University,Beijing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Psychosomatic Medicine,Beijing Hospital of Traditional Chinese Medicine, Capital Medical University,Beijing ,China"
            },
            {
                "name": "CHEN Jie",
                "org": "Department of Psychosomatic Medicine,Beijing Hospital of Traditional Chinese Medicine, Capital Medical University,Beijing ,China"
            }
        ],
        "venue": "Chinese Journal of Geriatric Heart Brain and Vessel Diseases",
        "year": 2012
    },
    "upMciIm1": {
        "id": "upMciIm1",
        "title": "Randomized Controlled Study of Depression Using Disease Management of Traditional Chinese Medicine Model",
        "abstract": "Objective Applying the disease management theory,to explore suitable disease management of traditional Chinese medicine model for depression patients,and observe its role in the therapeutic effects on depression.Methods The patients visiting depression special clinic of acupuncture and moxibustion department in Beijing TCM Hospital,Capital Medical University,from May 2010 to August 2010 were incorporated as the observation object,and were assigned into the management group and control group.The management group accepted the disease management of traditional Chinese medicine model,including antidepressant medicine treatment,education of traditional Chinese medicine model about depression,regular assessment and follow-up.Conventional treatment model and treatments were used for the control group.The intervention of both groups lasted for 24 weeks.The changes in measuring indicators including HAMD and CGI were observed before and at the end of week 4,8,12,16,20,24 of intervention.Results HAMD index showed significant difference at the end of week 12,16,20 and 24 of intervention,the management group was superior to the control group(P <0.05 or P <0.01).CGI index showed significant difference at the end of week 20 and 24 of intervention,the management group was superior to the control group(P <0.05 or P <0.01).Besides,at the end of week 24,the cure rate of the management group was higher than the control group(P <0.05).Conclusion The disease management of TCM model had the same effect in short-term effect as the conventional treatment model,while in long-term effect,the former is superior to the latter.",
        "keywords": [
            "disease management of traditional Chinese medicine",
            "efficacy",
            "depression"
        ],
        "authors": [
            {
                "name": "FAN Zhu-qing",
                "org": "Department of Acupuncture, Fuxing Hospital,Capital Medical University,Beijing ,China"
            },
            {
                "name": "CHEN Jie",
                "org": "Department of Psychosomatic Medicine,Beijing TCM Hospital,Capital Medical University,Beijing ,China"
            },
            {
                "name": "PEI Yin",
                "org": "Department of Psychosomatic Medicine,Beijing TCM Hospital,Capital Medical University,Beijing ,China"
            },
            {
                "name": "YANG Jing",
                "org": "Department of Psychosomatic Medicine,Beijing TCM Hospital,Capital Medical University,Beijing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Psychosomatic Medicine,Beijing TCM Hospital,Capital Medical University,Beijing ,China"
            }
        ],
        "venue": "Chinese Journal of Information on Traditional Chinese Medicine",
        "year": 2012
    },
    "bnRQusfW": {
        "id": "bnRQusfW",
        "title": "Analyzing the typical symptom of eating disorder by the theory of Inner Canon of Huangdi",
        "abstract": "Inner Canon of Huangdi(Inner Canon in short) is a classic medical literature which is existing in China.It reflects the medical achievements of ancient China,and is found in the theoretical system of medicine.It lays the foundation for the development of Chinese medicine.The article analyzes preliminary and discussion on the causes of the incidence of several typical clinical symptoms in patients with eating disorder from the perspective of Inner Canon of Huangdi,I hope that the clinical thinking will provide for treating the patients with eating disorder of TCM.",
        "keywords": [
            "Inner Canon of Huangdi",
            "Clinical symptoms",
            "Eating disorder"
        ],
        "authors": [
            {
                "name": "YANG Jing",
                "org": "Department of Acupuncture Center Psychosomatic Medicine,Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital University of Medical Sciences,Beijing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Acupuncture Center Psychosomatic Medicine,Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital University of Medical Sciences,Beijing ,China"
            },
            {
                "name": "LI Xueni",
                "org": "Peking University Sixth Hospital The Mental Health Institute of Beijing University,Beijing ,China"
            },
            {
                "name": "ZHANG Darong",
                "org": "Peking University Sixth Hospital The Mental Health Institute of Beijing University,Beijing ,China"
            }
        ],
        "venue": "China Medical Herald",
        "year": 2012
    },
    "vCMlztcN": {
        "id": "vCMlztcN",
        "title": "Study of intervention on the disease management of traditional Chinese medicine model on the treatment compliance of patients with depression",
        "abstract": "Objective To observe the influence of the disease management of traditional Chinese medicine model on the the treatment compliance of patients with depression by applying the disease management theory and technology.Methods The patients that went to doctor in depression special clinic of acupuncture and moxibustion department in Beijing hospital of traditional Chinese medicine affiliated to capital medical university from May 2010 to August 2010 were incorporated as the observation object,they were divided into management group(30 cases) and control group(30 cases).The patients who assigned in management group accepted the disease management of traditional Chinese medicine model such as antidepressant medicine treatment,education of traditional Chinese medicine model about depression,regular assessment and following.Conventional treatment model and treatments were used for the control group.The intervention of both group lasted for 24 weeks.The changes in measuring indicators including treatment compliance scale was observed in 4 weeks, 8weeks,12weeks,16 weeks,20 weeks,24 weeks after the intervention in order to observe the measuring indicators of the treatment compliance.Results ①The management group had more return visit times and longer treatment time which compared with control group(P<0.01).②The management group had higher compliance of drug treatment,there were more patients taking medicine according to doctor than control group(P<0.05 or P<0.01).③The higher compliance of acupuncture treatment was showed in the management group,there were more patients accepting acupuncture treatment over 3 times every week than control group from 0 to 8 weeks(P<0.01).From 9 to 24 weeks,the persistent acupuncture treatment rate of the management group is higher than the control group(P<0.01).Conclusion The disease management of traditional Chinese medicine model was superior to the conventional treatment model in the treatment compliance.",
        "keywords": [
            "Depression",
            "Disease management of traditional Chinese medicine",
            "Treatment compliance"
        ],
        "authors": [
            {
                "name": "FAN Zhuqing",
                "org": ""
            },
            {
                "name": "PEI Yin",
                "org": "Department of Psychosomatic Medicine,Beijing Traditional Chinese Medicine Hospital Affiliated to Capital Medical University, Beijing ,China"
            },
            {
                "name": "CHEN Jie",
                "org": "Department of Psychosomatic Medicine,Beijing Traditional Chinese Medicine Hospital Affiliated to Capital Medical University, Beijing ,China"
            },
            {
                "name": "YANG Jing",
                "org": "Department of Psychosomatic Medicine,Beijing Traditional Chinese Medicine Hospital Affiliated to Capital Medical University, Beijing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Psychosomatic Medicine,Beijing Traditional Chinese Medicine Hospital Affiliated to Capital Medical University, Beijing ,China"
            }
        ],
        "venue": "China Medical Herald",
        "year": 2012
    },
    "bHcEPeYV": {
        "id": "bHcEPeYV",
        "title": "Establishment and optimization Photinia frasery rapid propagation system",
        "abstract": "Using the stem segment with single bud as the explant,this paper probes into the effects of different concentration 6-BA,NAA,IBA on proliferation and plantlet regeneration of Photinia frasery. The results showed that the appropriate medium for bud induction is MS+6-BA 1.0 mg/L+NAA0.1 mg/L,the medium of multiplication is MS+6-BA 2.0 mg/L+ NAA 0.1 mg/L.Using orthogonal tests to determine the medium for plant grow is MS+6-BA 1.0 mg/L+IBA 0.2 mg/L+NAA 0.2 mg/L,and the medium of rooting is 1/2 MS +IBA 1.0～1.5 mg/L,with up to 100% survival rate.",
        "keywords": [
            "plantlet rapid propagation",
            "Photinia frasery",
            "orthogonal tests",
            "tissue culture"
        ],
        "authors": [
            {
                "name": "HOU Chun-yan",
                "org": "College of Life Science,Agricutural University of Hebei,Baoding ,China"
            },
            {
                "name": "REN Li-mei",
                "org": "College of Life Science,Agricutural University of Hebei,Baoding ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "College of Life Science,Agricutural University of Hebei,Baoding ,China"
            },
            {
                "name": "WANG Dong-mei",
                "org": "College of Life Science,Agricutural University of Hebei,Baoding ,China"
            }
        ],
        "venue": "Journal of Agricultural University of Hebei",
        "year": 2007
    },
    "cZih2If1": {
        "id": "cZih2If1",
        "title": "Study and Application of Transgenic Technology in Soybean Breeding",
        "abstract": "In this years,the main emphasis of transgenic technology in soybean has shifted to the establishment of efficient regenerated system and stable descendiblity system.With the development of the transgenic technology,there were several disease resistance and insect pest-resistant transgenic soybean had been made in our country.This paper introduced the receptor system used for soybean transgenic technology,which included the receptor system of organ generation,the receptor system of somatic embryogenesis,the receptor system of protoplast and so on.We also introduced the Transgenic method,which included Agrobacterium-mediated method and particle gun method.In the end,future research consideration of the soybean transformation was discussed.",
        "keywords": [
            "Agrobacterium tumefaciens",
            "Soybean",
            "Particle gun",
            "Genetic transformation"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Agricultural University of Hebei,Baoding ,China"
            },
            {
                "name": "ZHANG Dong-xu",
                "org": "Agricultural University of Hebei,Baoding ,China"
            },
            {
                "name": "SHANG Lei",
                "org": "Agricultural University of Hebei,Baoding ,China"
            }
        ],
        "venue": "Acta Agriculturae Boreali-Sinica",
        "year": 2008
    },
    "YxFi11oV": {
        "id": "YxFi11oV",
        "title": "Investigation on the valid path and method to strengthen the course teaching of cell engineering",
        "abstract": "Combining latest research result reform course contents,adopting diversification of teaching form in classroom,bettering experiment contents,paying attention to experiment vocational training, perfecting investigation system,investigating the valid path and method to strengthen the course teaching of cell engineering are put forward in this paper.",
        "keywords": [
            "open type teaching",
            "teaching method",
            "cell engineering"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "College of Life Science,Agricultural University of Hebei,Baoding ,China"
            },
            {
                "name": "CHEN Yan",
                "org": "College of Life Science,Agricultural University of Hebei,Baoding ,China"
            },
            {
                "name": "WANG Dong-mei",
                "org": "College of Life Science,Agricultural University of Hebei,Baoding ,China"
            },
            {
                "name": "LIU Gang",
                "org": "College of Life Science,Agricultural University of Hebei,Baoding ,China"
            }
        ],
        "venue": "Journal of Agricultural University of Hebei(Agriculture and Forestry Education Edition)",
        "year": 2008
    },
    "RMxibIO7": {
        "id": "RMxibIO7",
        "title": "Comparative studies on ultrastructural alteration of soybean infected with two different strains of soybean mosaic virus",
        "abstract": "The ultrastructural alteration of soybean cultivar jidou 7 leaves infected with SC-8 strain of SMV(Compatible combination)and N3 strain of SMV(Incompatible combination),respective- ly,was examined by the transmission electron microscope.The results showed:at the early stage(8 to 12 h after inoculation),chloroplasts dilated and nuclei agglomerated; at 24 h after infection,the changes of chloroplasts and nuclei were greater and the mitochondrion was complete; at the later stage(72 h after infection),nuclei degraded,and the membrane of nuclei and chloroplasts disap- peared.Mitochondria degradation had only two layers of membrane structure.There were only a few viruses observed in the cells,and the cylindrical inclusions were not found in cytoplasm.During the course,chloroplasts and nuclei were the first declined organs,but mitochondria was the last de- graded organ.In compatible combination the similar ultrastructural features changed 10 hours later than the incompatible combination,but the changes of nuclei,chloroplast and mitochondria were synchronous.These showed some characters of passive cell death.In addition,the starches synthe- sized in all the time before cell breakdown.In the cytoplasm the number of mitochondria increased abnormaly,perhaps for the sake of energy anabolism for virus multiplication.",
        "keywords": [
            "soybean mosaic virus",
            "chromatin agglutinization",
            "soybean",
            "pathological ultrastructural alteration"
        ],
        "authors": [
            {
                "name": "LI Wen-long",
                "org": "College of Life Sciences,Agricultural University of Hebei,Baoding ,China"
            },
            {
                "name": "WANG Yue-ming",
                "org": "College of Life Sciences,Agricultural University of Hebei,Baoding ,China"
            },
            {
                "name": "HOU Chun-Yan",
                "org": "College of Life Sciences,Agricultural University of Hebei,Baoding ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "College of Life Sciences,Agricultural University of Hebei,Baoding ,China"
            },
            {
                "name": "ZHANG Meng-chen",
                "org": "Institute of Food and Oil Crops,Hebei Academy of Agricultural and Forestry Sciences,Shijiazhuang ,China"
            },
            {
                "name": "WANG Dong-mei",
                "org": "College of Life Sciences,Agricultural University of Hebei,Baoding ,China"
            }
        ],
        "venue": "Journal of Agricultural University of Hebei",
        "year": 2008
    },
    "50GxKERk": {
        "id": "50GxKERk",
        "title": "Study on the regeneration system of soybean embryonic tips",
        "abstract": "This experiment established an effective regeneration system with high-quailty soybean of Hebei by exploring the effects of the types,inducing time and the concentration of hormones on explants of embryonic tips,and comparing the differences between two regeneration systems of soy- bean from cotyledonay nodes and embryonic tips.The results indicated that the optimal concentra- tion of 6-BA from 0.5 to 1.0 mg/L,and the optimal inducing time was 5 d.The regeneration rate of embryonic tips was obviously higher than cotyledonary nodes.The regeneration system of soybean embryonic tips had the merit of higher regeneration rate,simpler and more convenient operation, shorter cycle and better repeatability.",
        "keywords": [
            "cotyledonay nodes",
            "embryonic tips",
            "regeneration system",
            "soybean"
        ],
        "authors": [
            {
                "name": "ZHANG Dong-xu",
                "org": "College of Life Sciences,Agricultural University of Hebei,Baoding ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "College of Life Sciences,Agricultural University of Hebei,Baoding ,China"
            },
            {
                "name": "SHANG Lei",
                "org": "College of Life Sciences,Agricultural University of Hebei,Baoding ,China"
            },
            {
                "name": "ZHANG Yun-wei",
                "org": "College of Life Sciences,Agricultural University of Hebei,Baoding ,China"
            },
            {
                "name": "YANG Chun-yan",
                "org": "Institute of Food and Oil Crops, Hebei Academy of Agricultural and Forestry Sciences,Shijiazhuang ,China"
            },
            {
                "name": "WANG Dong-mei",
                "org": "College of Life Sciences,Agricultural University of Hebei,Baoding ,China"
            }
        ],
        "venue": "Journal of Agricultural University of Hebei",
        "year": 2008
    },
    "aE1jbLrt": {
        "id": "aE1jbLrt",
        "title": "Studies on the decreasing browning of callus and the establishment of suspension cell lines from Photinia frasery",
        "abstract": "Asepsis leaves of Photinia frasery were employed to study callus tissue culture and establishment of suspension cell lines.The results showed that the appropriate medium for callus induction is MS+6-BA 0.5 mg/L +2,4-D 1.0 mg/L+NAA 0.1 mg/L;Inductivity is up to 97%;And the medium of multiplication is MS+6-BA 1.0 mg/L+NAA 0.1 mg/L.Orthogonal tests were performed to find out the effects of different adsorbents,anti-oxidants and other factors on callus browning.The medium for anti-browning is MS+6-BA 1.0 mg/L +NAA 0.2 mg/L+VitC 1.0 mg/L+Ch 100 mg/L with1% sugar.The calli obtained were subsequently cultured in liquid medium 1/2 MS+6-BA 1.0 mg/L +NAA 0.1 mg/L with 2% sugar,pH 5.5 for establishing suspension cell lines.The cells present good shape,dispersivity and bright yellow color.",
        "keywords": [
            "browning",
            "callus",
            "Photinia frasery",
            "cell suspension culture"
        ],
        "authors": [
            {
                "name": "REN Li-mei",
                "org": "College of Life Science,Agricultural University of Hebei,Baoding ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "College of Life Science,Agricultural University of Hebei,Baoding ,China"
            },
            {
                "name": "ZHAO Li-hong",
                "org": "The Administrative Office of Baoding Transportation Bureau,Baoding ,China"
            },
            {
                "name": "WANG Dong-mei",
                "org": "College of Life Science,Agricultural University of Hebei,Baoding ,China"
            }
        ],
        "venue": "Journal of Agricultural University of Hebei",
        "year": 2008
    },
    "uYCUpZau": {
        "id": "uYCUpZau",
        "title": "H_2O_2 induced programmed cell death of wheat suspension cells",
        "abstract": "In order to study the effects of H2O2 on the suspension cells of wheat(Lovrin 10),the death rate,the changes of karyomorphology and the integrity of genomic DNA induced by different concentration of H2O2 were examined using bromphenol blue staining,improved phenol fuchsin staining and agarose gel electrophoresis.The results showed that the death rate of cells was gradually increased when the concentration of H2O2 was increased and the time after the treatment of H2O2 prolonged.At the same time the highly condensed chromatin in the cell nucleus accumulated during this process,and DNA ladder was detected by agarose gel electrophoresis.It can be summed up that H2O2 may induce programmed cell death of wheat suspension cells.",
        "keywords": [
            "H2O2",
            "suspension cells of wheat",
            "programmed cell death(PCD)"
        ],
        "authors": [
            {
                "name": "REN Li-mei",
                "org": "College of Life Science,Agricultural University of Hebei,Baoding ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "College of Life Science,Agricultural University of Hebei,Baoding ,China"
            },
            {
                "name": "CHEN Yan",
                "org": "College of Life Science,Agricultural University of Hebei,Baoding ,China"
            },
            {
                "name": "WANG Dong-mei",
                "org": "College of Life Science,Agricultural University of Hebei,Baoding ,China"
            }
        ],
        "venue": "Journal of Agricultural University of Hebei",
        "year": 2009
    },
    "btR9ODfX": {
        "id": "btR9ODfX",
        "title": "The practice and exploration for Basic Biochemistry teaching in current situation",
        "abstract": "Biochemistry disciplines developed rapidly,biochemical teaching content has been greatly accumulated and enriched.At present,due to reform of higher education to promote broading route and accumulating foundation,teaching period decreases gradually,course content and teaching period compression becomes increasingly prominent.In this paper,we discussed interrelated means impactful from adjusting the teaching contents,improving teaching effective and extenting the way of study based on some experience from several years' work on teaching.",
        "keywords": [
            "improving teaching effective",
            "biochemistry",
            "adjusting the teaching contents",
            "extenting the way of study"
        ],
        "authors": [
            {
                "name": "LIU Gang",
                "org": "College of Life Science,Agricultural University of Hebei,Baoding ,China"
            },
            {
                "name": "YU Xiu-mei",
                "org": "College of Life Science,Agricultural University of Hebei,Baoding ,China"
            },
            {
                "name": "CHEN Yan",
                "org": "College of Life Science,Agricultural University of Hebei,Baoding ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "College of Life Science,Agricultural University of Hebei,Baoding ,China"
            },
            {
                "name": "DOU Shi-juan",
                "org": "College of Life Science,Agricultural University of Hebei,Baoding ,China"
            },
            {
                "name": "HOU Chun-yan",
                "org": "College of Life Science,Agricultural University of Hebei,Baoding ,China"
            },
            {
                "name": "HAN Sheng-fang",
                "org": "College of Life Science,Agricultural University of Hebei,Baoding ,China"
            },
            {
                "name": "WANG Dong-mei",
                "org": "College of Life Science,Agricultural University of Hebei,Baoding ,China"
            }
        ],
        "venue": "Journal of Agricultural University of Hebei(Agriculture and Forestry Education Edition)",
        "year": 2009
    },
    "HCi2lJGm": {
        "id": "HCi2lJGm",
        "title": "Initial exploration in biologic experimental reformof teaching in Universities",
        "abstract": "Experimental teaching is an important aspact of biologic teaching system in university.It is playing an important role in cultivating practical abilitiy and creative ability of the students.In this paper some initial ideas were proposed in content of course,teching methods and the reform in examination of the experimental teaching.",
        "keywords": [
            "teaching reform",
            "practical abilitiy",
            "creative ability",
            "experimental teaching"
        ],
        "authors": [
            {
                "name": "CHEN Yan",
                "org": "College of Life Science,Agricultural University of Hebei,Baoding ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "College of Life Science,Agricultural University of Hebei,Baoding ,China"
            },
            {
                "name": "LIU Gang",
                "org": "College of Life Science,Agricultural University of Hebei,Baoding ,China"
            },
            {
                "name": "LIU Na",
                "org": "College of Life Science,Agricultural University of Hebei,Baoding ,China"
            },
            {
                "name": "WANG Dong-mei",
                "org": "College of Life Science,Agricultural University of Hebei,Baoding ,China"
            }
        ],
        "venue": "Journal of Agricultural University of Hebei(Agriculture and Forestry Education Edition)",
        "year": 2009
    },
    "o8s44LbW": {
        "id": "o8s44LbW",
        "title": "Expression of plasma membrane H~+-ATPase in soybean root by semi RT-PCR systems under low phosphorus stress",
        "abstract": "In this experiment,a semi RT-PCR system was established to detect the gene expression of PM H+-ATPase in soybean root under phosphorus deficiency quickly and conveniently,in which β-tubulin gene was used as reference gene.The results showed that the gene of PM H+-ATPase was up-regulated under low P environment for 2 h and increased gradually until 4 h,but the gene expression decreased a little as the time delayed to 6 h.It was shown that gene expression changes of PM H+-ATPase may be related to the adaptation of the phosphorus deficiency stress,furthermore,the semi-quantitative RT-PCR system could be used to detect gene expression under different conditions successfully.",
        "keywords": [
            "semi-quantitative PCR",
            "soybean[Glycine max(L.)Merrill]",
            "phosphorus deficiency stress",
            "plasma membrane H+-ATPase"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Lifes Science College Agricultural University of Hebei,Baoding ,China"
            },
            {
                "name": "ZHANG Xiao-hong",
                "org": "Baoding Agricultural Bureau,Baoding ,China"
            },
            {
                "name": "ZHANG Zhen-hai",
                "org": "Lifes Science College Agricultural University of Hebei,Baoding ,China"
            },
            {
                "name": "HAN Sheng-fang",
                "org": "Lifes Science College Agricultural University of Hebei,Baoding ,China"
            },
            {
                "name": "WANG Dong-mei",
                "org": "Lifes Science College Agricultural University of Hebei,Baoding ,China"
            }
        ],
        "venue": "Journal of Agricultural University of Hebei",
        "year": 2009
    },
    "XVIlUJ8Q": {
        "id": "XVIlUJ8Q",
        "title": "Establishment of effective regeneration system of Nepenthes mirabilis",
        "abstract": "The axillary buds of Nepenthes mirabilis were used as specimens.The effect of different concentration inorganic salt,sucrose,BA,IBA and NAA for tissue culture and rapid propagation were studied.The results showed that the 1/2MS medium with sucrose 30 g/L,BA 2.0 mg/L and NAA 0.2 mg/ L was the best for multiplication culture.The 1/4MS medium with sucrose 15 g/L,IBA 1.5 mg /L and NAA 0.5 mg/L was the best treatment for inducing roots from shoots,and the rootage ratio was 92%.",
        "keywords": [
            "Nepenthes mirabilis",
            "root",
            "multiplication",
            "tissue culture"
        ],
        "authors": [
            {
                "name": "ZHENG Wen-yong",
                "org": "College of Life Science,Agricultural University of Hebei,Baoding ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "College of Life Science,Agricultural University of Hebei,Baoding ,China"
            },
            {
                "name": "YANG Quan",
                "org": "College of Life Science,Agricultural University of Hebei,Baoding ,China"
            },
            {
                "name": "ZHAO Shao-rong",
                "org": "College of Life Science,Agricultural University of Hebei,Baoding ,China"
            },
            {
                "name": "WANG Yang",
                "org": "College of Life Science,Agricultural University of Hebei,Baoding ,China"
            },
            {
                "name": "WANG Dong-mei",
                "org": "College of Life Science,Agricultural University of Hebei,Baoding ,China"
            }
        ],
        "venue": "Journal of Agricultural University of Hebei",
        "year": 2010
    },
    "pXeFeu2R": {
        "id": "pXeFeu2R",
        "title": "Study on the Genotypes of Soybean Varieties under Different NaCl Concentration Stress",
        "abstract": "In this experiment,using tissue culture approach to study eight high-quality soybean varieties of Hebei for NaCl stress by morphological indexs. The morphological indexs include seedling height,length of hypocotyl and root. The results showed that different genotype had the different NaCl tolerance from the morphology,under NaCl concentration of 35 mmol/L,the seedling height,length of root of Jidou17,Wuxing2 and Wuxing3 were significantly inhibited,and significant difference with the control.",
        "keywords": [
            "Length of hypocotyls",
            "Soybean",
            "Length of root",
            "Seeding hight"
        ],
        "authors": [
            {
                "name": "SHANG Lei",
                "org": " Agricultural University of Hebei,Baoding ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": " Agricultural University of Hebei,Baoding ,China"
            },
            {
                "name": "ZHANG Meng-chen",
                "org": " Institute of Food and Oil Crops,Hebei Academy of Agriculture and Forestry Sciences,Shijiazhuang ,China"
            },
            {
                "name": "WANG Dong-mei",
                "org": " Agricultural University of Hebei,Baoding ,China"
            }
        ],
        "venue": "Acta Agriculturae Boreali-Sinica",
        "year": 2010
    },
    "36DBenCi": {
        "id": "36DBenCi",
        "title": "Conditions for establishment of cell suspension culture of wheat \"5389\"",
        "abstract": "Rataria of wheat \"5389\" were cultured to study the effect of different mediums on callus induction and the estate of the callus.The results showed that in MS+2,4-D 3.0 mg/L culture medium the highest ratio of callus induced was 93.42%,and in MS+2,4-D 1.0 mg/L+KT 0.1 mg/L maintenance medium the embryonal callus were obtained and cell suspension culture of wheat \"5389\" was established.These results provided a good system for further study on how the elicitor can induce the defense reaction of host.",
        "keywords": [
            "wheat",
            "suspension culture",
            "callus",
            "rataria"
        ],
        "authors": [
            {
                "name": "QIAO Mei",
                "org": "College of Life Science,Agricultural University of Hebei,Baoding ,China"
            },
            {
                "name": "CHEN Yan",
                "org": "College of Life Science,Agricultural University of Hebei,Baoding ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "College of Life Science,Agricultural University of Hebei,Baoding ,China"
            },
            {
                "name": "WANG Dong-mei",
                "org": "College of Life Science,Agricultural University of Hebei,Baoding ,China"
            }
        ],
        "venue": "Journal of Agricultural University of Hebei",
        "year": 2010
    },
    "KkO3tqHR": {
        "id": "KkO3tqHR",
        "title": "Effect of foliar application of KH_2PO_4 after harvest on the maturation of branch for tetraploid grape (Vitis vinifera L.cv.\"Muscat Hamburg\")",
        "abstract": "The effects of different concentrations of KH2PO4 on branch maturation of tetraploid grape(Vitis vinifera L.cv.\"Muscat Hamburg\") were studied.The results showed that foliar spray of 0.3% KH2PO4 every 15 days after harvest could accelerate the maturation of branch,improve the nutrient accumulation and improve cold-resistance.All of them were necessary for safe hibernation of plant and accumulated necessary nutrients necessary for the germination for the next year.",
        "keywords": [
            "foliar spraying KH2PO4",
            "branch mature",
            "tetraploid grape(Vitis vinifera L.cv.\"Muscat Hamburg\")"
        ],
        "authors": [
            {
                "name": "TANG Xiao-dong",
                "org": "College of Life Science,Agricultural University of Hebei,Baoding ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "College of Life Science,Agricultural University of Hebei,Baoding ,China"
            },
            {
                "name": "HAN Sheng-fang",
                "org": "College of Life Science,Agricultural University of Hebei,Baoding ,China"
            },
            {
                "name": "WANG Dong-mei",
                "org": "College of Life Science,Agricultural University of Hebei,Baoding ,China"
            }
        ],
        "venue": "Journal of Agricultural University of Hebei",
        "year": 2011
    },
    "tOO0gYXX": {
        "id": "tOO0gYXX",
        "title": "Research Progress on Plant Tissue Culture Technology",
        "abstract": "The development current situation of plant tissue culture technology in breeding,industrial propagation,germplasm conservation,production of secondary metabolites,photoautotrophic tissue culture techniques and the application of high technology in tissue culture production etc were summarized in this paper.",
        "keywords": [
            "transgenic",
            "breeding",
            "plant tissue culture technology",
            "photoautotrophic tissue culture techniques",
            "LED"
        ],
        "authors": [
            {
                "name": "ZHANG Dong-xu",
                "org": "Business Department of Horticulture,Beijing Kingpeng International High Technology Corporation,Beijing "
            },
            {
                "name": "ZHOU Zeng-chan",
                "org": "Business Department of Horticulture,Beijing Kingpeng International High Technology Corporation,Beijing "
            },
            {
                "name": "BU Yun-long",
                "org": "Business Department of Horticulture,Beijing Kingpeng International High Technology Corporation,Beijing "
            },
            {
                "name": "ZHANG Jie",
                "org": "College of Life Sciences,Hebei Agricultural University,Baoding,Hebei "
            },
            {
                "name": "ZHANG Xiao-wen",
                "org": "Scientific Research Centre,Beijing Agricultural Machinery Institute,Beijing "
            },
            {
                "name": "ZHANG Cheng-bo",
                "org": "Chinese Academy of Agricultural Sciences,Beijing "
            },
            {
                "name": "CAI Wei-Jian",
                "org": "Business Department of Horticulture,Beijing Kingpeng International High Technology Corporation,Beijing "
            },
            {
                "name": "KANG Jing",
                "org": "Business Department of Horticulture,Beijing Kingpeng International High Technology Corporation,Beijing "
            },
            {
                "name": "XIAO Zheng",
                "org": "Business Department of Horticulture,Beijing Kingpeng International High Technology Corporation,Beijing "
            }
        ],
        "venue": "Northern Horticulture",
        "year": 2011
    },
    "i8GZbsMV": {
        "id": "i8GZbsMV",
        "title": "Electrolyte Leakage and Electrical Impedance Spectroscopy Methods Assessing Frost Hardiness of F_1 Genotypes between Populus×canadensis Moench cv.'Neva'×Populus ussuriensis Kom.during Dehardening",
        "abstract": "Frost hardiness(FH) of 8 genotypes from F1 hybrid between Populus×canadensis cv.'Neva'×Popu-lus ussuriensis Kom.during dehardening was assessed by methods of electrical impedance spectroscopy(EIS) and electrolyte leakage(EL),and correlation between the results of two methods was compared in order to find the optimum EIS parameters for measuring the FH of the F1 genotypes.Three-year-old F1 genotypes and their female parent were sampled for EIS and EL analysis.The results indicated that:(1) FH of 8 F1 genotypes decreased during dehardening with a sequence of NK36>NK41>NK61>NK57>NK42>NK60>NK58>NK56,which were superior to 'Neva';(2) Linear correlation between the results of EIS(τ) and EL in assessing FH was significant(R2=0.965).However,FH of EIS was underestimated than that of EL;(3) Without controlled freezing tests,extracellular resistance(re) and relaxation time(τ) of EIS were highly correlated with FH of EL(R2 were 0.817 and 0.847,respectively).",
        "keywords": [
            "relaxation time(τ)",
            "extracellular resistance(re)",
            "F1 hybrid between Populus×euranericana cv.'Neva'×P.ussuriensis Kom.",
            "frost hardiness",
            "dehardening"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "College of Horticulture,Agricultural University of Hebei,Baoding,Hebei ,China"
            },
            {
                "name": "ZHANG Gang",
                "org": "College of Horticulture,Agricultural University of Hebei,Baoding,Hebei ,China"
            },
            {
                "name": "LI Jin-Hua",
                "org": "State Key Laboratory of Tree Genetics and Breeding,Research Institute of Forestry,Chinese Academy of Forestry,Beijing ,China"
            },
            {
                "name": "ZHANG Zhen-Ying",
                "org": "College of Horticulture,Agricultural University of Hebei,Baoding,Hebei ,China"
            }
        ],
        "venue": "Plant Physiology Journal",
        "year": 2012
    },
    "fcw0zyHm": {
        "id": "fcw0zyHm",
        "title": "The overall planning of Tang River Agriculture and Forestry Technology Park in Quyang County",
        "abstract": "According to the present conditions of Tang River in Quyang County and the development orientation of ecology and landscape,a complete planning of agriculture and forestry technology park was conducted from the aspects of functional division,system of the road,plant landscape,proposing a set of the natural appearance,agricultural production,high-tech demonstration,leisure tour entertainment in the plan of ecological agriculture and forestry technology park,which aims to highlight the spirit of a venue in the agriculture and forestry technology park and the notion of tourism to promote agriculture and forestry,in order to achieve harmony and unity of multiple functions of agriculture and forestry technology park.",
        "keywords": [
            "Tang River",
            "Quyang County",
            "planning",
            "tourism",
            "landscape ecology",
            "agriculture and forestry technology park"
        ],
        "authors": [
            {
                "name": "SUN Ya-ling",
                "org": "College of Landscape Architecture and Tourism,Agricultural University of Hebei, Baoding ,China"
            },
            {
                "name": "ZHANG Tao",
                "org": "College of Landscape Architecture and Tourism,Agricultural University of Hebei, Baoding ,China"
            },
            {
                "name": "DUAN Da-juan",
                "org": "College of Landscape Architecture and Tourism,Agricultural University of Hebei, Baoding ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "College of Landscape Architecture and Tourism,Agricultural University of Hebei, Baoding ,China"
            }
        ],
        "venue": "Hebei Journal of Forestry and Orchard Research",
        "year": 2012
    },
    "mnqkM895": {
        "id": "mnqkM895",
        "title": "Exact nonparametric inference for detection of nonlinearity",
        "abstract": "We propose an exact nonparametric inference scheme for the detection of nonlinear- ity. The essential fact utilized in our scheme is that, for a linear stochastic process with jointly symmetric innovations, its ordinary least square (OLS) linear predic- tion error is symmetric about zero. Based on this viewpoint, a class of linear signed rank statistics, e.g. the Wilcoxon signed rank statistic, can be derived with the known null distributions from the prediction error. Thus one of the advantages of our scheme is that, it can provide exact confidence levels for our null hypothesis tests. Furthermore, the exactness is applicable for finite samples. We demonstrate the test power of this statistic through several examples.",
        "keywords": [
            "surrogate data method",
            "nonlinearity",
            "null hypothesis test",
            "statistical inference"
        ],
        "authors": [
            {
                "name": "Xiaodong Luo",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Michael Small",
                "org": ""
            },
            {
                "name": "Irene Moroz",
                "org": ""
            }
        ],
        "venue": "",
        "year": 0
    },
    "O3tGfQGA": {
        "id": "O3tGfQGA",
        "title": "Exact nonparametric inference for detection of nonlinear determinism",
        "abstract": "We propose an exact nonparametric inference scheme for the detection of\nnonlinear determinism. The essential fact utilized in our scheme is that, for a\nlinear stochastic process with jointly symmetric innovations, its ordinary\nleast square (OLS) linear prediction error is symmetric about zero. Based on\nthis viewpoint, a class of linear signed rank statistics, e.g. the Wilcoxon\nsigned rank statistic, can be derived with the known null distributions from\nthe prediction error. Thus one of the advantages of our scheme is that, it can\nprovide exact confidence levels for our null hypothesis tests. Furthermore, the\nexactness is applicable for finite samples with arbitrary length. We\ndemonstrate the test power of this statistic through several examples.",
        "keywords": [
            "surrogate data method",
            "nonlinearity",
            "null hypothesis test",
            "statistical inference",
            "hypothesis test",
            "prediction error",
            "confidence level",
            "ordinary least square",
            "stochastic process"
        ],
        "authors": [
            {
                "name": "Xiaodong Luo",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Michael Small",
                "org": ""
            },
            {
                "name": "Irene Moroz",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2005
    },
    "sqRS4rln": {
        "id": "sqRS4rln",
        "title": "Optimal phase-space projection for noise reduction.",
        "abstract": "In this communication we will reexamine the widely studied technique of phase-space projection. By imposing a time-domain constraint on the residual noise, we deduce a more general version of the optimal projector, which includes those appearing in previous literature as subcases but does not assume the independence between the clean signal and the noise. As an application, we will apply this technique for noise reduction. Numerical results show that our algorithm has succeeded in augmenting the signal-to-noise ratio for simulated data from the Rössler system and experimental speech record.",
        "keywords": [],
        "authors": [
            {
                "name": "Xiaodong Luo",
                "org": "Department of Electronic and Information Engineering|Hong Kong Polytechnic University"
            },
            {
                "name": "Jie Zhang",
                "org": "Department of Electronic and Information Engineering|Hong Kong Polytechnic University"
            },
            {
                "name": "Michael Small",
                "org": "Department of Electronic and Information Engineering|Hong Kong Polytechnic University"
            }
        ],
        "venue": "Physical review. E, Statistical, nonlinear, and soft matter physics",
        "year": 2005
    },
    "QEWCaFCJ": {
        "id": "QEWCaFCJ",
        "title": "Detecting temporal and spatial correlations in pseudoperiodic time series.",
        "abstract": "Recently there has been much attention devoted to exploring the complicated possibly chaotic dynamics in pseudoperiodic time series. Two methods [Zhang, Phys. Rev. E 73, 016216 (2006); Zhang and Small, Phys. Rev. Lett. 96, 238701 (2006)] have been forwarded to reveal the chaotic temporal and spatial correlations, respectively, among the cycles in the time series. Both these methods treat the cycle as the basic unit and design specific statistics that indicate the presence of chaotic dynamics. In this paper, we verify the validity of these statistics to capture the chaotic correlation among cycles by using the surrogate data method. In particular, the statistics computed for the original time series are compared with those from its surrogates. The surrogate data we generate is pseudoperiodic type (PPS), which preserves the inherent periodic components while destroying the subtle nonlinear (chaotic) structure. Since the inherent chaotic correlations among cycles, either spatial or temporal (which are suitably characterized by the proposed statistics), are eliminated through the surrogate generation process, we expect the statistics from the surrogate to take significantly different values than those from the original time series. Hence the ability of the statistics to capture the chaotic correlation in the time series can be validated. Application of this procedure to both chaotic time series and real world data clearly demonstrates the effectiveness of the statistics. We have found clear evidence of chaotic correlations among cycles in human electrocardiogram and vowel time series. Furthermore, we show that this framework is more sensitive to examine the subtle changes in the dynamics of the time series due to the match between PPS surrogate and the statistics adopted. It offers a more reliable tool to reveal the possible correlations among cycles intrinsic to the chaotic nature of the pseudoperiodic time series.",
        "keywords": [],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Xiaodong Luo",
                "org": ""
            },
            {
                "name": "Tomomichi Nakamura",
                "org": ""
            },
            {
                "name": "Junfeng Sun",
                "org": ""
            },
            {
                "name": "Michael Small",
                "org": ""
            }
        ],
        "venue": "Physical review. E, Statistical, nonlinear, and soft matter physics",
        "year": 2007
    },
    "q0lRsHlL": {
        "id": "q0lRsHlL",
        "title": "Fast communication: Extension of the local subspace method to enhancement of speech with colored noise",
        "abstract": "Based on dynamic features of human speech, the local projection (LP) method has been adapted to the enhancement of speech corrupted by white noise. As an extension of the LP method, a strategy with two rounds of projection is introduced to enhance the speech contaminated with colored noise. Colored noise mainly resides in a low dimensional subspace, and is assumed to be stationary in this communication. At step one, a noise dominated subspace is first estimated with colored noise obtained from speech silence frame. Then for the reference phase point, the components, projected into the noise dominated subspace, are deleted and the enhanced speech is reconstructed with the remaining components. The residual error of the output of step one tends to distribute uniformly on each direction. So at step two, the LP method is further applied to the output of step one, treating the residual error as white noise. An adaption of this strategy to continuous speech is performed. The results show that this strategy is more effective than the LP method in enhancing speech corrupted by colored noise, and is comparable to two typical speech enhancement methods.",
        "keywords": [
            "speech silence frame",
            "speech enhancement",
            "residual error",
            "colored noise",
            "continuous speech",
            "enhanced speech",
            "typical speech enhancement method",
            "lp method",
            "local subspace method",
            "low dimensional subspace",
            "fast communication",
            "white noise",
            "human speech"
        ],
        "authors": [
            {
                "name": "Junfeng Sun",
                "org": "Department of Electronic and Information Engineering, Hong Kong Polytechnic University, Hong Kong, China"
            },
            {
                "name": "Jie Zhang",
                "org": "Department of Electronic and Information Engineering, Hong Kong Polytechnic University, Hong Kong, China"
            },
            {
                "name": "Michael Small",
                "org": "Department of Electronic and Information Engineering, Hong Kong Polytechnic University, Hong Kong, China"
            }
        ],
        "venue": "Signal Processing",
        "year": 2008
    },
    "9cpDTRcP": {
        "id": "9cpDTRcP",
        "title": "Detecting and describing pseudo-periodic dynamics from time series",
        "abstract": "Time series measurements are sequential records of physical variables such as velocity, temperature, or pressure that are collected over some period of time from a dynamical process of interest. Many time series in the real world display apparent irregular behavior or fluctuations that carry abundant information regarding the underlying process. Given such a time series, a most fundamental question to ask is: Does the underlying dynamics originate from a low-dimensional deterministic (possibly chaotic) process, or is it governed by stochastic ones? If the system is proved to be chaotic, or at least contains deterministic component, how can we characterize such signals and further extract relevant information reliably in the presence of different kinds of noise or nonstationarity? In this thesis, we intend to answer the above questions. In particular, we focus on those time series that demonstrate strong periodic behavior known as pseudoperiodic time series. Such signals are abundant in natural and physiological systems, e.g., annual sunspot numbers, laser output, human electrocardiogram (ECG) and gait data. The paradigm of chaos introduced decades ago has provided a potential explanation for the seemingly erratic and apparently unpredictable behavior of the time series. However, traditional statistics like Lyapunov exponent and correlation dimension cannot confirm chaos absolutely in that noise tends to mask or mimic deterministic behaviors. In addition, the available techniques seeking determinism originated from dynamical system theory are not always suitable or perform poorly for analyzing pseudoperiodic data, because the presence of strong periodicity may hide the underlying fractal structures. We have developed novel methods to address the problem of faithfully detecting and characterizing temporal and spatial correlations in pseudoperiodic time series that are noisy and nonstationary in this thesis. Utilizing the inherent periodicity, we first segment the time series into consecutive cycles and adopt the correlation coefficient as a measure of their distance, which forms the foundation for subsequent analysis. In detecting temporal correlation, we construct a number of cycle-reordered time series that preserves progressively less determinism than the original one. We check the number of cycle pairs in the new time series that share similar dynamical evolution to those in the original time series. Appropriate statistics are then devised to quantify how this correlation decays within and across each new time series, so that the original dynamics can be inferred reliably. In terms of spatial correlation, we have for the first time proposed a transformation from time domain to the complex network domain, with the cycles from the time series represented by nodes in the corresponding network. The dynamics of the time series thus can be readily explored through the topology of the corresponding network, and various topological indices have greatly enhanced our understanding of the complex dynamics of the time series. The validity of the above methods is further verified by using the pseudoperiodic surrogate (PPS) method. The ability of the statistics to capture the correlation among cycles can be validated by finding significant differences between the original time series and its PPS in terms of the new statistics used. This in turn has formed a framework that is more sensitive to examine the subtle changes in the dynamics. Finally we apply the proposed methods to various experimental data such as human ECG, vowel data, gait signal, and laser data. The intrinsic correlations among cycles in such time series are clearly revealed and effectively quantified by our methods, which provide new insights into the understanding of the complex physiological systems. Meanwhile, the new statistics are shown to be very promising in discriminating between healthy and pathological state from visually indistinguishable biomedical recordings.",
        "keywords": [
            "time domain",
            "time series",
            "time series measurement",
            "pseudo-periodic dynamic",
            "new time series",
            "corresponding network",
            "pseudoperiodic time series",
            "cycle-reordered time series",
            "spatial correlation",
            "new statistic",
            "original time series"
        ],
        "authors": [
            {
                "name": "Michael Small",
                "org": "Hong Kong Polytechnic University (Hong Kong)"
            },
            {
                "name": "Jie Zhang",
                "org": "Hong Kong Polytechnic University (Hong Kong)"
            }
        ],
        "venue": "Detecting and describing pseudo-periodic dynamics from time series",
        "year": 2008
    },
    "LJf91WS2": {
        "id": "LJf91WS2",
        "title": "Extension of the local subspace method to enhancement of speech with colored noise",
        "abstract": "Based on dynamic features of human speech, the local projection (LP) method has been adapted to the enhancement of speech corrupted by white noise. As an extension of the LP method, a strategy with two rounds of projection is introduced to enhance the speech contaminated with colored noise. Colored noise mainly resides in a low dimensional subspace, and is assumed to be stationary in this communication. At step one, a noise dominated subspace is first estimated with colored noise obtained from speech silence frame. Then for the reference phase point, the components, projected into the noise dominated subspace, are deleted and the enhanced speech is reconstructed with the remaining components. The residual error of the output of step one tends to distribute uniformly on each direction. So at step two, the LP method is further applied to the output of step one, treating the residual error as white noise. An adaption of this strategy to continuous speech is performed. The results show that this strategy is more effective than the LP method in enhancing speech corrupted by colored noise, and is comparable to two typical speech enhancement methods.",
        "keywords": [
            "speech enhancement",
            "colored noise",
            "local subspace method",
            "white noise"
        ],
        "authors": [
            {
                "name": "Junfeng Sun",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": "Department of Electronic and Information Engineering, Hong Kong Polytechnic University, Hong Kong, China"
            },
            {
                "name": "Michael Small",
                "org": "Department of Electronic and Information Engineering, Hong Kong Polytechnic University, Hong Kong, China"
            }
        ],
        "venue": "Signal Processing",
        "year": 2008
    },
    "BfUVprY6": {
        "id": "BfUVprY6",
        "title": "Changing motif distributions in complex networks by manipulating rich-club connections",
        "abstract": "The role of rich-club connectivity is significant in the structural property and functional behavior of complex networks. In this study, we find whether or not a very small portion of rich nodes connected to each other can strongly affect the frequency of occurrence of basic building blocks (motifs) within a heterogeneous network. Conversely whether a homogeneous network has a rich-club or not generally has no significant effect on its structure. These findings open the possibility to optimize and control the structure of complex networks by manipulating rich-club connections. Furthermore, based on the subgraph ratio profile, we develop a more rigorous approach to judge whether a network has a rich-club or not. The new method does not calculate how many links there are among rich nodes but depends on how the links among rich nodes can affect the overall structure as well as the function of a given network. © 2011 Elsevier B.V. All rights reserved.",
        "keywords": [
            "complex network",
            "motif",
            "rich-club connection",
            "subgraph",
            "heterogeneous network"
        ],
        "authors": [
            {
                "name": "Xiaoke Xu",
                "org": "Hong Kong Polytechnic University(Hong Kong Polytechnic University,The Hong Kong Polytechnic University),Hong Kong,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Ping Li",
                "org": "Hong Kong Polytechnic University(Hong Kong Polytechnic University,The Hong Kong Polytechnic University),Hong Kong,China"
            },
            {
                "name": "Michael Small",
                "org": "Hong Kong Polytechnic University(Hong Kong Polytechnic University,The Hong Kong Polytechnic University),Hong Kong,China"
            }
        ],
        "venue": "Physica A: Statistical Mechanics and its Applications",
        "year": 2011
    },
    "mZWwUgkE": {
        "id": "mZWwUgkE",
        "title": "Increased Coupling in the Saliency Network is the main cause/effect of Attention Deficit Hyperactivity Disorder",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "xiaoxi ji",
                "org": ""
            },
            {
                "name": "wei cheng",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "tian ge",
                "org": ""
            },
            {
                "name": "li sun",
                "org": ""
            },
            {
                "name": "yufeng wang",
                "org": ""
            },
            {
                "name": "jianfeng feng",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2011
    },
    "DmlCJKvH": {
        "id": "DmlCJKvH",
        "title": "Emergence of scaling and assortative mixing through altruism",
        "abstract": "Highlights ► We propose a simple new modification to the standard preferential attachment mechanism. ► New links are created by altruistic attachment mechanism. ► Avoid systematic disassortative bias of BA networks while maintaining the same degree distribution. ► We find that such altruistic networks are structural more robust.",
        "keywords": [
            "scale-free",
            "assortativity",
            "altruism",
            "correlation",
            "modeling",
            "network model",
            "degree distribution",
            "power law",
            "scale free",
            "social network"
        ],
        "authors": [
            {
                "name": "Ping Li",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Michael Small",
                "org": ""
            }
        ],
        "venue": "Physica A: Statistical Mechanics and its Applications",
        "year": 2011
    },
    "lwGd8xhP": {
        "id": "lwGd8xhP",
        "title": "Dynamical influence of nodes revisited: A Markov chain analysis of epidemic process on networks",
        "abstract": "We provide a theoretical analysis of node importance from the perspective of dynamical processes on networks. In particular, using Markov chain analysis of the susceptible-infected-susceptible (SIS) epidemic model on networks, we derive the node importance in terms of dynamical behaviors on network in a theoretical way. It is found that this quantity happens to be the eigenvector centrality under some conditions, which bridges the topological centrality measure of the nodes with the dynamical influence of the nodes for the dynamical process. We furthermore discuss the condition under which the eigenvector centrality is valid for dynamical phenomena on networks. © 2012 Chinese Physical Society and IOP Publishing Ltd.",
        "keywords": [
            "markov chain",
            "epidemic model",
            "eigenvectors"
        ],
        "authors": [
            {
                "name": "Ping Li",
                "org": "Southwest Petroleum University China(Southwest Petroleum University),Chengdu,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Xiaoke Xu",
                "org": "Hong Kong Polytechnic University(Hong Kong Polytechnic University,The Hong Kong Polytechnic University),Hong Kong,China"
            },
            {
                "name": "Michael Small",
                "org": "University of Western Australia(University of Western Australia),Perth,Australia"
            }
        ],
        "venue": "Chinese Physics Letters",
        "year": 2012
    },
    "Wi6Bg1SX": {
        "id": "Wi6Bg1SX",
        "title": "Awake language mapping for cerebral glioma surgery",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "jinsong wu",
                "org": ""
            },
            {
                "name": "junfeng lu",
                "org": ""
            },
            {
                "name": "chengjun yao",
                "org": ""
            },
            {
                "name": "yanyan song",
                "org": ""
            },
            {
                "name": "ying mao",
                "org": ""
            },
            {
                "name": "liangfu zhou",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2012
    },
    "Q8gXt4ZB": {
        "id": "Q8gXt4ZB",
        "title": "Degree-based attacks are not optimal for desynchronization in general networks.",
        "abstract": "Suppressing harmful synchronization in complex networked systems is receiving increasing interest in various contexts including epileptic seizure and the Internet and traffic congestion. It is traditionally believed that by disrupting the most important nodes (i.e., those nodes of high degrees) synchronization can be effectively mitigated. However, this approach can perform poorly in more general situations such as homogeneous (random) or small world networks. In this article, we investigate how topological properties, such as the heterogeneity of the network can have an impact on its desynchronization. In particular, we propose a topology-aware scheme that chooses topologically sufficiently diversified contrarian nodes by taking into account the patterns of connectivity among them. Hence, a maximal number of nodes in the network can be influenced, leading to a more global impact and greater disruption to synchronization. Our scheme demonstrates significantly improved performance on various networked systems including homogeneous networks, small world, and even scale-free networks.",
        "keywords": [],
        "authors": [
            {
                "name": "Ping Li",
                "org": "Southwest Petroleum University China(Southwest Petroleum University),Chengdu,China"
            },
            {
                "name": "Xian Sun",
                "org": "Southwest Petroleum University China(Southwest Petroleum University),Chengdu,China"
            },
            {
                "name": "Kai Zhang",
                "org": "NEC Laboratories America, Inc.(NEC Research Institute,NEC Laboratories America,NEC Research Inst),Princeton,United States"
            },
            {
                "name": "Jie Zhang",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Michael Small",
                "org": "University of Western Australia(University of Western Australia),Perth,Australia"
            }
        ],
        "venue": "Physical review. E, Statistical, nonlinear, and soft matter physics",
        "year": 2013
    },
    "wsYUeZRJ": {
        "id": "wsYUeZRJ",
        "title": "142 3.0T iMRI Guided Resection in Cerebral Glioma Surgery: Interim Analysis of a Prospective, Randomized, Triple-Blind, Parallel-Controlled Trial",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "junfeng lu",
                "org": ""
            },
            {
                "name": "tianming qiu",
                "org": ""
            },
            {
                "name": "chengjun yao",
                "org": ""
            },
            {
                "name": "dongxiao zhuang",
                "org": ""
            },
            {
                "name": "jinsong wu",
                "org": ""
            },
            {
                "name": "xiu gong",
                "org": ""
            },
            {
                "name": "yanyan song",
                "org": ""
            },
            {
                "name": "liangfu zhou",
                "org": ""
            },
            {
                "name": "ying mao",
                "org": ""
            },
            {
                "name": "wei zhu",
                "org": ""
            }
        ],
        "venue": "Neurosurgery",
        "year": 2013
    },
    "YTvEvHnD": {
        "id": "YTvEvHnD",
        "title": "Coevolutionary dynamics of opinion propagation and social balance: The key role of small-worldness",
        "abstract": "\nThe propagation of various opinions in social networks, which influences human inter-relationships and even social structure, and hence is a most important part of social life. We have incorporated social balance into opinion propagation in social networks are influenced by social balance. The edges in networks can represent both friendly or hostile relations, and change with the opinions of individual nodes. We introduce a model to characterize the coevolutionary dynamics of these two dynamical processes on Watts-Strogatz (WS) small-world network. We employ two distinct evolution rules (i) opinion renewal; and (ii) relation adjustment. By changing the rewiring probability, and thus the small-worldness of the WS network, we found that the time for the system to reach balanced states depends critically on both the average path length and clustering coefficient of the network, which is different than other networked process like epidemic spreading. In particular, the system equilibrates most quickly when the underlying network demonstrates strong small-worldness, i.e., small average path lengths and large clustering coefficient. We also find that opinion clusters emerge in the process of the network approaching the global equilibrium, and a measure of global contrariety is proposed to quantify the balanced state of a social network.\n",
        "keywords": [
            "Statistical and Nonlinear Physics"
        ],
        "authors": [
            {
                "name": "yan chen",
                "org": "southwest petroleum university"
            },
            {
                "name": "lixue chen",
                "org": "southwest petroleum university"
            },
            {
                "name": "xian sun",
                "org": "southwest petroleum university"
            },
            {
                "name": "kai zhang",
                "org": "nec"
            },
            {
                "name": "jie zhang",
                "org": "fudan university"
            },
            {
                "name": "ping li",
                "org": "southwest petroleum university"
            }
        ],
        "venue": "European Physical Journal B",
        "year": 2014
    },
    "4uAymIpZ": {
        "id": "4uAymIpZ",
        "title": "3.0T iMRI-guided resection of eloquent high-grade gliomas: preliminary results of a randomised controlled trial",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "xiu gong",
                "org": ""
            },
            {
                "name": "chengjun yao",
                "org": ""
            },
            {
                "name": "shiwen yuan",
                "org": ""
            },
            {
                "name": "dongxiao zhuang",
                "org": ""
            },
            {
                "name": "tianming qiu",
                "org": ""
            },
            {
                "name": "junfeng lu",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "yanyan song",
                "org": ""
            },
            {
                "name": "wei zhu",
                "org": ""
            },
            {
                "name": "ying mao",
                "org": ""
            },
            {
                "name": "jinsong wu",
                "org": ""
            },
            {
                "name": "liangfu zhou",
                "org": ""
            }
        ],
        "venue": "The Lancet",
        "year": 2015
    },
    "b47c642M": {
        "id": "b47c642M",
        "title": "From Categorical to Numerical: Multiple Transitive Distance Learning and Embedding.",
        "abstract": "Categorical data are ubiquitous in real-world databases. However, due to the lack of an intrinsic proximity measure, many powerful algorithms for numerical data analysis may not work well on their categorical counterparts, making it a bottleneck in practical applications. In this paper, we propose a novel method to transform categorical data to numerical representations, so that abundant numerical learning methods can be exploited in categorical data mining. Our key idea is to learn a pairwise dissimilarity among categorical symbols, henceforth a continuous embedding, which can then be used for subsequent numerical treatment. There are two important criteria for learning the dissimilarities. First, it should capture the important “transitivity” which has shown to be particularly useful in measuring the proximity relation in categorical data. Second, the pairwise sample geometry arising from the learned symbol distances should be maximally consistent with prior knowledge (e.g., class labels) to obtain a good generalization performance. We achieve them through multiple transitive distance learning and embedding. Encouraging results are observed on a number of benchmark classification tasks against state-of-the-art.",
        "keywords": [],
        "authors": [
            {
                "name": "Kai Zhang",
                "org": ""
            },
            {
                "name": "Qiaojun Wang",
                "org": ""
            },
            {
                "name": "Zhengzhang Chen",
                "org": ""
            },
            {
                "name": "Ivan Marsic",
                "org": ""
            },
            {
                "name": "Vipin Kumar",
                "org": ""
            },
            {
                "name": "Guofei Jiang",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            }
        ],
        "venue": "SDM",
        "year": 2015
    },
    "t8P7Gk87": {
        "id": "t8P7Gk87",
        "title": "Variability of structurally constrained and unconstrained functional connectivity in schizophrenia",
        "abstract": "In this thesis, entropy is used to characterize intrinsic ageing properties of the human brain. Analysis of fMRI data from a large dataset of individuals, using resting state BOLD signals, demonstrated that a functional connectivity entropy associated with brain activity increases with age. During an average lifespan, the entropy, which was calculated from a population of individuals, increased by approximately 0.1 bits, due to correlations in BOLD activity becoming more widely distributed. This is attributed to the number of excitatory neurons and the excitatory conductance decreasing with age. Incorporating these properties into a computational model leads to quantitatively similar results to the fMRI data. The dataset involved males and females and significant differences were found between them. The entropy of males at birth was lower than that of females. However, the entropies of the two sexes increase at different rates, and intersect at approximately 50 years; after this age, males have a larger entropy.In addition, the connectivity between different brain areas provides evidence about normal function and dysfunction. Changes are described in the distribution of these connectional strengths in schizophrenia using a large sample of resting-state fMRI data. The functional connectivity entropy, which measures the dispersion of the functional connectivity distribution, was lower in patients with schizophrenia than in controls, reflecting a reduction in both strong positive and negative correlations between brain regions. The decrease in the functional connectivity entropy was strongly associated with an increase in the positive, negative, and general symptoms. Using an integrate-and-fire simulation model based on anatomical connectivity, it is shown that a reduction in the efficacy of the NMDA mediated excitatory synaptic inputs can reduce the functional connectivity entropy to resemble the pattern seen in schizophrenia.Spatial variation in connectivity is an integral aspect of the brainu0027s architecture. In the absence of this variability, the brain may act as a single homogenous entity without regional specialization. In this thesis, we investigate the variability in functional links categorized on the basis of the presence of direct structural paths (primary) or indirect paths mediated by one (secondary) or more (tertiary) brain regions ascertained by diffusion tensor imaging. We quantified the variability in functional connectivity using an unbiased estimate of unpredictability (functional connectivity entropy) in a neuropsychiatric disorder where structure-function relationship is considered to be abnormal. 34 patients and 32 healthy controls underwent DTI and resting state functional MRI scans. Less than one-third (27.4% in patients, 27.85% in controls) of functional links between brain regions were regarded as direct primary links on the basis of DTI tractography, while the rest were secondary or tertiary. The most significant changes in the distribution of functional connectivity in schizophrenia occur in indirect tertiary paths with no direct axonal linkage in both early (p=0.0002, d=1.46) and late (p=1_10",
        "keywords": [
            "diffusion tensor imaging",
            "schizophrenia"
        ],
        "authors": [
            {
                "name": "ye yao",
                "org": "university of warwick"
            },
            {
                "name": "lena palaniyappan",
                "org": ""
            },
            {
                "name": "peter f liddle",
                "org": "institute of mental health"
            },
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "susan t francis",
                "org": "university of nottingham"
            },
            {
                "name": "jianfeng feng",
                "org": "university of warwick"
            }
        ],
        "venue": "Human Brain Mapping",
        "year": 2015
    },
    "NF60Tmug": {
        "id": "NF60Tmug",
        "title": "Lévy Walk Navigation in Complex Networks: A Distinct Relation between Optimal Transport Exponent and Network Dimension.",
        "abstract": "We investigate, for the first time, navigation on networks with a Lévy walk strategy such that the step probability scales as pij ~ dij(-α), where dij is the Manhattan distance between nodes i and j, and α is the transport exponent. We find that the optimal transport exponent α(opt) of such a diffusion process is determined by the fractal dimension df of the underlying network. Specially, we theoretically derive the relation α(opt) = df + 2 for synthetic networks and we demonstrate that this holds for a number of real-world networks. Interestingly, the relationship we derive is different from previous results for Kleinberg navigation without or with a cost constraint, where the optimal conditions are α = df and α = df + 1, respectively. Our results uncover another general mechanism for how network dimension can precisely govern the efficient diffusion behavior on diverse networks.",
        "keywords": [],
        "authors": [
            {
                "name": "Tongfeng Weng",
                "org": "HKUST-DT System and Media Laboratory, Hong Kong University of Science and Technology, HongKong."
            },
            {
                "name": "Michael Small",
                "org": "The University of Western Australia, Crawley, WA 6009, Australia."
            },
            {
                "name": "Jie Zhang",
                "org": "Centre for Computational Systems Biology, Fudan University, China."
            },
            {
                "name": "Pan Hui",
                "org": "HKUST-DT System and Media Laboratory, Hong Kong University of Science and Technology, HongKong."
            }
        ],
        "venue": "Scientific reports",
        "year": 2015
    },
    "jSmm6pVV": {
        "id": "jSmm6pVV",
        "title": "Direct evidence from intraoperative electrocortical stimulation indicates shared and distinct speech production center between Chinese and English languages.",
        "abstract": "",
        "keywords": [
            "chinese",
            "neurosurgery"
        ],
        "authors": [
            {
                "name": "jinsong wu",
                "org": "fudan university"
            },
            {
                "name": "junfeng lu",
                "org": "fudan university"
            },
            {
                "name": "han zhang",
                "org": "university of north carolina at chapel hill"
            },
            {
                "name": "jie zhang",
                "org": "fudan university"
            },
            {
                "name": "chengjun yao",
                "org": "fudan university"
            },
            {
                "name": "dongxiao zhuang",
                "org": "fudan university"
            },
            {
                "name": "tianming qiu",
                "org": "fudan university"
            },
            {
                "name": "qihao guo",
                "org": "fudan university"
            },
            {
                "name": "xiaobing hu",
                "org": "fudan university"
            },
            {
                "name": "ying mao",
                "org": "fudan university"
            },
            {
                "name": "liangfu zhou",
                "org": "fudan university"
            }
        ],
        "venue": "Human Brain Mapping",
        "year": 2015
    },
    "WNOxzI8A": {
        "id": "WNOxzI8A",
        "title": "Metabolic approach for tumor delineation in glioma surgery: 3D MR spectroscopy image-guided resection.",
        "abstract": "OBJECT The extent of resection is one of the most essential factors that influence the outcomes of glioma resection. However, conventional structural imaging has failed to accurately delineate glioma margins because of tumor cell infiltration. Three-dimensional proton MR spectroscopy ((1)H-MRS) can provide metabolic information and has been used in preoperative tumor differentiation, grading, and radiotherapy planning. Resection based on glioma metabolism information may provide for a more extensive resection and yield better outcomes for glioma patients. In this study, the authors attempt to integrate 3D (1)H-MRS into neuronavigation and assess the feasibility and validity of metabolically based glioma resection. METHODS Choline (Cho)-N-acetylaspartate (NAA) index (CNI) maps were calculated and integrated into neuronavigation. The CNI thresholds were quantitatively analyzed and compared with structural MRI studies. Glioma resections were performed under 3D (1)H-MRS guidance. Volumetric analyses were performed for metabolic and structural images from a low-grade glioma (LGG) group and high-grade glioma (HGG) group. Magnetic resonance imaging and neurological assessments were performed immediately after surgery and 1 year after tumor resection. RESULTS Fifteen eligible patients with primary cerebral gliomas were included in this study. Three-dimensional (1)H-MRS maps were successfully coregistered with structural images and integrated into navigational system. Volumetric analyses showed that the differences between the metabolic volumes with different CNI thresholds were statistically significant (p < 0.05). For the LGG group, the differences between the structural and the metabolic volumes with CNI thresholds of 0.5 and 1.5 were statistically significant (p = 0.0005 and 0.0129, respectively). For the HGG group, the differences between the structural and metabolic volumes with CNI thresholds of 0.5 and 1.0 were statistically significant (p = 0.0027 and 0.0497, respectively). All patients showed no tumor progression at the 1-year follow-up. CONCLUSIONS This study integrated 3D MRS maps and intraoperative navigation for glioma margin delineation. Optimum CNI thresholds were applied for both LGGs and HGGs to achieve resection. The results indicated that 3D (1)H-MRS can be integrated with structural imaging to provide better outcomes for glioma resection.",
        "keywords": [
            "1H-MRS = proton MR spectroscopy",
            "CNI = choline-NAA index",
            "CSI = chemical shift imaging",
            "Cho = choline",
            "DICOM = digital imaging and communications in medicine",
            "DTI = diffusion tensor imaging",
            "EOR = extent of resection",
            "GTR = gross-total resection",
            "HGG = high-grade glioma",
            "LGG = low-grade glioma",
            "MPRAGE = magnetization-prepared rapid gradient-echo",
            "NAA = N-acetylaspartate",
            "OS = overall survival",
            "PFS = progression-free survival",
            "PT = pyramidal tract",
            "ROI = region of interest",
            "STR = subtotal resection",
            "VOI = volume of interest",
            "fMRI = functional MR imaging",
            "glioma",
            "magnetic resonance spectroscopy",
            "neuronavigation",
            "oncology",
            "surgical planning"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Glioma Surgery Division, Department of Neurologic Surgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai;"
            },
            {
                "name": "Dong-Xiao Zhuang",
                "org": "Glioma Surgery Division, Department of Neurologic Surgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai;"
            },
            {
                "name": "Cheng-Jun Yao",
                "org": "Glioma Surgery Division, Department of Neurologic Surgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai;"
            },
            {
                "name": "Ching-Po Lin",
                "org": "Centre for Computational Systems Biology, Fudan University, Shanghai; and."
            },
            {
                "name": "Tian-Liang Wang",
                "org": "BrainLAB (Beijing) Medical Equipment Trading Co., Ltd., Beijing, People's Republic of China."
            },
            {
                "name": "Zhi-Yong Qin",
                "org": "Glioma Surgery Division, Department of Neurologic Surgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai;"
            },
            {
                "name": "Jin-Song Wu",
                "org": "Glioma Surgery Division, Department of Neurologic Surgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai;"
            }
        ],
        "venue": "Journal of neurosurgery",
        "year": 2015
    },
    "nEGPEKXQ": {
        "id": "nEGPEKXQ",
        "title": "Differential alterations of resting-state functional connectivity in generalized anxiety disorder and panic disorder.",
        "abstract": "Generalized anxiety disorder (GAD) and panic disorder (PD) are most common anxiety disorders with high lifetime prevalence while the pathophysiology and disease-specific alterations still remain largely unclear. Few studies have taken a whole-brain perspective in the functional connectivity (FC) analysis of these two disorders in resting state. It limits the ability to identify regionally and psychopathologically specific network abnormalities with their subsequent use as diagnostic marker and novel treatment strategy. The whole brain FC using a novel FC metric was compared, that is, scaled correlation, which they demonstrated to be a reliable FC statistics, but have higher statistical power in two-sample t-test of whole brain FC analysis. About 21 GAD and 18 PD patients were compared with 22 matched control subjects during resting-state, respectively. It was found that GAD patients demonstrated increased FC between hippocampus/parahippocampus and fusiform gyrus among the most significantly changed FC, while PD was mainly associated with greater FC between somatosensory cortex and thalamus. Besides such regional specificity, it was observed that psychopathological specificity in that the disrupted FC pattern in PD and GAD correlated with their respective symptom severity. The findings suggested that the increased FC between hippocampus/parahippocampus and fusiform gyrus in GAD were mainly associated with a fear generalization related neural circuit, while the greater FC between somatosensory cortex and thalamus in PD were more likely linked to interoceptive processing. Due to the observed regional and psychopathological specificity, their findings bear important clinical implications for the potential treatment strategy. Hum Brain Mapp, 2016. © 2016 Wiley Periodicals, Inc.",
        "keywords": [
            "anxiety disorders",
            "fear",
            "functional magnetic resonance imaging (fMRI)",
            "generalization",
            "interoception",
            " whole brain functional connectivity analysis"
        ],
        "authors": [
            {
                "name": "Huiru Cui",
                "org": "Shanghai Key Laboratory of Psychotic Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China."
            },
            {
                "name": "Jie Zhang",
                "org": "Centre for Computational Systems Biology, Fudan University, Shanghai, People's Republic of China."
            },
            {
                "name": "Yicen Liu",
                "org": "Centre for Computational Systems Biology, Fudan University, Shanghai, People's Republic of China."
            },
            {
                "name": "Qingwei Li",
                "org": "Department of Psychiatry, Tongji Hospital of Tongji University, Shanghai, People's Republic of China."
            },
            {
                "name": "Hui Li",
                "org": "Shanghai Key Laboratory of Psychotic Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China."
            },
            {
                "name": "Lanlan Zhang",
                "org": "Shanghai Key Laboratory of Psychotic Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China."
            },
            {
                "name": "Qiang Hu",
                "org": "Shanghai Key Laboratory of Psychotic Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China."
            },
            {
                "name": "Wei Cheng",
                "org": "Centre for Computational Systems Biology, Fudan University, Shanghai, People's Republic of China."
            },
            {
                "name": "Qiang Luo",
                "org": "Centre for Computational Systems Biology, Fudan University, Shanghai, People's Republic of China."
            },
            {
                "name": "Jianqi Li",
                "org": "Shanghai Key Laboratory of Magnetic Resonance, Department of Physics, East China Normal University, Shanghai, People's Republic of China."
            },
            {
                "name": "Wei Li",
                "org": "Shanghai Key Laboratory of Psychotic Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China."
            },
            {
                "name": "Jijun Wang",
                "org": "Shanghai Key Laboratory of Psychotic Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China."
            },
            {
                "name": "Jianfeng Feng",
                "org": "Centre for Computational Systems Biology, Fudan University, Shanghai, People's Republic of China."
            },
            {
                "name": "Chunbo Li",
                "org": "Shanghai Key Laboratory of Psychotic Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China."
            },
            {
                "name": "Georg Northoff",
                "org": "Institute of Mental Health Research, University of Ottawa, Ottawa, Canada."
            }
        ],
        "venue": "Human brain mapping",
        "year": 2016
    },
    "840DQ1Rg": {
        "id": "840DQ1Rg",
        "title": "Community Size Effects on Epidemic Spreading in Multiplex Social Networks.",
        "abstract": "The dynamical process of epidemic spreading has drawn much attention of the complex network community. In the network paradigm, diseases spread from one person to another through the social ties amongst the population. There are a variety of factors that govern the processes of disease spreading on the networks. A common but not negligible factor is people's reaction to the outbreak of epidemics. Such reaction can be related information dissemination or self-protection. In this work, we explore the interactions between disease spreading and population response in terms of information diffusion and individuals' alertness. We model the system by mapping multiplex networks into two-layer networks and incorporating individuals' risk awareness, on the assumption that their response to the disease spreading depends on the size of the community they belong to. By comparing the final incidence of diseases in multiplex networks, we find that there is considerable mitigation of diseases spreading for full phase of spreading speed when individuals' protection responses are introduced. Interestingly, the degree of community overlap between the two layers is found to be critical factor that affects the final incidence. We also analyze the consequences of the epidemic incidence in communities with different sizes and the impacts of community overlap between two layers. Specifically, as the diseases information makes individuals alert and take measures to prevent the diseases, the effective protection is more striking in small community. These phenomena can be explained by the multiplexity of the networked system and the competition between two spreading processes.",
        "keywords": "",
        "authors": [
            {
                "name": "Ting Liu",
                "org": "Center for Intelligent and Networked Systems, School of Computer Science, Southwest Petroleum University, Chengdu 610500, China."
            },
            {
                "name": "Ping Li",
                "org": "Center for Intelligent and Networked Systems, School of Computer Science, Southwest Petroleum University, Chengdu 610500, China."
            },
            {
                "name": "Yan Chen",
                "org": "Center for Intelligent and Networked Systems, School of Computer Science, Southwest Petroleum University, Chengdu 610500, China."
            },
            {
                "name": "Jie Zhang",
                "org": "Center for Computational Systems Biology, Fudan University, Shanghai 200433, China."
            }
        ],
        "venue": "PloS one",
        "year": 2016
    },
    "fbVLljQn": {
        "id": "fbVLljQn",
        "title": "Seeing the Forest from the Trees in Two Looks: Matrix Sketching by Cascaded Bilateral Sampling.",
        "abstract": "Matrix sketching is aimed at finding close approximations of a matrix by factors of much smaller dimensions, which has important applications in optimization and machine learning. Given a matrix A of size m by n, state-of-the-art randomized algorithms take O(m * n) time and space to obtain its low-rank decomposition. Although quite useful, the need to store or manipulate the entire matrix makes it a computational bottleneck for truly large and dense inputs. Can we sketch an m-by-n matrix in O(m + n) cost by accessing only a small fraction of its rows and columns, without knowing anything about the remaining data? In this paper, we propose the cascaded bilateral sampling (CABS) framework to solve this problem. We start from demonstrating how the approximation quality of bilateral matrix sketching depends on the encoding powers of sampling. In particular, the sampled rows and columns should correspond to the code-vectors in the ground truth decompositions. Motivated by this analysis, we propose to first generate a pilot-sketch using simple random sampling, and then pursue more advanced,  sampling on the pilot-sketch factors seeking maximal encoding powers. In this cascading process, the rise of approximation quality is shown to be lower-bounded by the improvement of encoding powers in the follow-up sampling step, thus theoretically guarantees the algorithmic boosting property. Computationally, our framework only takes linear time and space, and at the same time its performance rivals the quality of state-of-the-art algorithms consuming a quadratic amount of resources. Empirical evaluations on benchmark data fully demonstrate the potential of our methods in large scale matrix sketching and related areas.",
        "keywords": "",
        "authors": [
            {
                "name": "Kai Zhang",
                "org": ""
            },
            {
                "name": "Chuanren Liu",
                "org": ""
            },
            {
                "name": "Jie Zhang 0012",
                "org": ""
            },
            {
                "name": "Hui Xiong",
                "org": ""
            },
            {
                "name": "Eric P. Xing",
                "org": ""
            },
            {
                "name": "Jieping Ye",
                "org": ""
            }
        ],
        "venue": "arXiv: Learning",
        "year": 2016
    },
    "rzZCpA2w": {
        "id": "rzZCpA2w",
        "title": "Navigation by anomalous random walks on complex networks",
        "abstract": "A Nature Research Journal",
        "keywords": "",
        "authors": [
            {
                "name": "Tongfeng Weng",
                "org": "HKUST-DT System and Media Laboratory, Hong Kong University of Science and Technology, HongKong"
            },
            {
                "name": "Moein Khajehnejad",
                "org": "HKUST-DT System and Media Laboratory, Hong Kong University of Science and Technology, HongKong"
            },
            {
                "name": "Rui Zheng",
                "org": "HKUST-DT System and Media Laboratory, Hong Kong University of Science and Technology, HongKong"
            },
            {
                "name": "Pan Hui",
                "org": "HKUST-DT System and Media Laboratory, Hong Kong University of Science and Technology, HongKong"
            },
            {
                "name": "Jie Zhang",
                "org": "Centre for Computational Systems Biology, Fudan University, China"
            },
            {
                "name": "Michael Small",
                "org": "The University of Western Australia, Crawley, WA 6009, Australia"
            },
            {
                "name": "Michael Small",
                "org": "Mineral Resources, CSIRO, Kensington, WA, Australia"
            }
        ],
        "venue": "Scientific Reports",
        "year": 2016
    },
    "AREdEoRm": {
        "id": "AREdEoRm",
        "title": "Neural, electrophysiological and anatomical basis of brain-network variability and its characteristic changes in mental disorders",
        "abstract": "See Mattar et al . (doi:[10.1093/aww151][1]) for a scientific commentary on this article. Functional brain networks demonstrate significant temporal variability and dynamic reconfiguration even in the resting state. Currently, most studies investigate temporal variability of brain networks at the scale of single (micro) or whole-brain (macro) connectivity. However, the mechanism underlying time-varying properties remains unclear, as the coupling between brain  variability and neural activity is not readily apparent when analysed at either micro or macroscales. We propose an intermediate (meso) scale analysis and characterize temporal variability of the functional architecture associated with a particular region. This yields a topography of variability that reflects the whole-brain and, most importantly, creates an analytical framework to establish the fundamental relationship between variability of regional functional architecture and its neural activity or structural connectivity. We find that temporal variability reflects the dynamical reconfiguration of a brain region into distinct functional modules at different times and may be indicative of brain flexibility and adaptability. Primary and unimodal sensory-motor cortices demonstrate low temporal variability, while transmodal areas, including heteromodal association areas and limbic system, demonstrate the high variability. In particular, regions with highest variability such as hippocampus/parahippocampus, inferior and middle temporal gyrus, olfactory gyrus and caudate are all related to learning, suggesting that the temporal variability may indicate the level of brain adaptability. With simultaneously recorded electroencephalography/functional magnetic resonance  and functional magnetic resonance imaging/diffusion tensor  data, we also find that variability of regional functional architecture is modulated by local blood oxygen  activity and α-band oscillation, and is governed by the ratio of intra- to inter-community structural connectivity. Application of the mesoscale variability measure to multicentre datasets of three mental disorders and matched controls involving 1180 subjects reveals that those regions demonstrating extreme, i.e. highest/lowest variability in controls are most liable to change in mental disorders. Specifically, we draw attention to the identification of diametrically opposing patterns of variability changes between schizophrenia and attention deficit hyperactivity disorder/autism. Regions of the default-mode  demonstrate lower variability in patients with schizophrenia, but high variability in patients with autism/attention deficit hyperactivity disorder, compared with respective controls. In contrast, subcortical regions, especially the thalamus, show higher variability in schizophrenia patients, but lower variability in patients with attention deficit hyperactivity disorder. The changes in variability of these regions are also closely related to symptom scores. Our work provides insights into the dynamic organization of the resting brain and how it changes in brain disorders. The nodal variability measure may also be potentially useful as a predictor for learning and neural rehabilitation.*   Abbreviations    :       ADHD    :   attention deficit hyperactivity disorder    BOLD    :   blood oxygen level-dependent    DMN    :   default-mode network    DTI    :   diffusion tensor imaging    RIIC    :   ratio of intra- to intercommunity structural connection [1]: /lookup/doi/10.1093/brain/aww151",
        "keywords": "",
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "1 Institute of Science and Technology for Brain-Inspired Intellegence, Fudan University, Shanghai 200433, PR China"
            },
            {
                "name": "Jie Zhang",
                "org": "1 Institute of Science and Technology for Brain-Inspired Intellegence, Fudan University, Shanghai 200433, PR China"
            },
            {
                "name": "Wei Cheng",
                "org": "1 Institute of Science and Technology for Brain-Inspired Intellegence, Fudan University, Shanghai 200433, PR China"
            },
            {
                "name": "Zhaowen Liu",
                "org": "1 Institute of Science and Technology for Brain-Inspired Intellegence, Fudan University, Shanghai 200433, PR China"
            },
            {
                "name": "Zhaowen Liu",
                "org": "1 Institute of Science and Technology for Brain-Inspired Intellegence, Fudan University, Shanghai 200433, PR China"
            },
            {
                "name": "Kai Zhang",
                "org": "4 NEC Laboratories America, 4 Independence Way, Princeton, NJ 08540, USA"
            },
            {
                "name": "Xu Lei",
                "org": ""
            },
            {
                "name": "Ye Yao",
                "org": "1 Institute of Science and Technology for Brain-Inspired Intellegence, Fudan University, Shanghai 200433, PR China"
            },
            {
                "name": "Benjamin Becker",
                "org": "7 Key Laboratory for Neuroinformation, Center for Information in Medicine, University of Electronic Science and Technology of China, Chengdu, PR China"
            },
            {
                "name": "Yicen Liu",
                "org": "1 Institute of Science and Technology for Brain-Inspired Intellegence, Fudan University, Shanghai 200433, PR China"
            },
            {
                "name": "Keith M. Kendrick",
                "org": ""
            },
            {
                "name": "Guangming Lu",
                "org": "2 Department of Medical Imaging, Jinling Hospital, Nanjing University School of Medicine, Nanjing 210002, PR China"
            },
            {
                "name": "Jianfeng Feng",
                "org": "1 Institute of Science and Technology for Brain-Inspired Intellegence, Fudan University, Shanghai 200433, PR China"
            },
            {
                "name": "Jianfeng Feng",
                "org": "1 Institute of Science and Technology for Brain-Inspired Intellegence, Fudan University, Shanghai 200433, PR China"
            }
        ],
        "venue": "Brain",
        "year": 2016
    },
    "EwRYDj0w": {
        "id": "EwRYDj0w",
        "title": "Brain-Wide Analysis of Functional Connectivity in First-Episode and Chronic Stages of Schizophrenia",
        "abstract": "Published reports of functional abnormalities in schizophrenia remain divergent due to lack of staging point-of-view and whole-brain analysis. To identify key functional-connectivity differences of first-episode (FE) and chronic patients from controls using resting-state functional MRI, and determine changes that are specifically associated with disease onset, a clinical staging model is adopted. We analyze functional-connectivity differences in prodromal, FE (mostly drug naive), and chronic patients from their matched controls from 6 independent datasets involving a total of 789 participants (343 patients). Brain-wide functional-connectivity analysis was performed in different datasets and the results from the datasets of the same stage were then integrated by meta-analysis, with Bonferroni correction for multiple comparisons. Prodromal patients differed from controls in their pattern of functional-connectivity involving the inferior frontal gyri (Broca’s area). In FE patients, 90% of the functional-connectivity changes involved the frontal lobes, mostly the inferior frontal gyrus including Broca’s area, and these changes were correlated with delusions/blunted affect. For chronic patients, functional-connectivity differences extended to wider areas of the brain, including reduced thalamo-frontal connectivity, and increased thalamo-temporal and thalamo-sensorimoter connectivity that were correlated with the positive, negative, and general symptoms, respectively. Thalamic changes became prominent at the chronic stage. These results provide evidence for distinct patterns of functional-dysconnectivity across FE and chronic stages of schizophrenia. Importantly, abnormalities in the frontal language networks appear early, at the time of disease onset. The identification of stage-specific pathological processes may help to understand the disease course of schizophrenia and identify neurobiological markers crucial for early diagnosis.",
        "keywords": "",
        "authors": [
            {
                "name": "Tao Li",
                "org": "1The Mental Health Center and the Psychiatric Laboratory, West China Hospital, Sichuan University, Chengdu, PR China;"
            },
            {
                "name": "Qiang Wang",
                "org": "1The Mental Health Center and the Psychiatric Laboratory, West China Hospital, Sichuan University, Chengdu, PR China;"
            },
            {
                "name": "Jie Zhang",
                "org": "3Institute of Science and Technology for Brain Inspired Intelligence, Fudan University, Shanghai, PR China;"
            },
            {
                "name": "Jie Zhang",
                "org": "3Institute of Science and Technology for Brain Inspired Intelligence, Fudan University, Shanghai, PR China;"
            },
            {
                "name": "Edmund T. Rolls",
                "org": "5Oxford Centre for Computational Neuroscience, Oxford, UK;"
            },
            {
                "name": "W Yang",
                "org": "7Shanghai Center for Mathematical Sciences, Shanghai, PR China;"
            },
            {
                "name": "Lena Palaniyappan",
                "org": "8Division of Psychiatry and Applied Psychology, University of Nottingham, Centre for Translational Neuroimaging, Institute of Mental Health, Nottingham, UK;"
            },
            {
                "name": "Lena Palaniyappan",
                "org": "8Division of Psychiatry and Applied Psychology, University of Nottingham, Centre for Translational Neuroimaging, Institute of Mental Health, Nottingham, UK;"
            },
            {
                "name": "Lanlan Zhang",
                "org": "7Shanghai Center for Mathematical Sciences, Shanghai, PR China;"
            },
            {
                "name": "Wei Cheng",
                "org": "3Institute of Science and Technology for Brain Inspired Intelligence, Fudan University, Shanghai, PR China;"
            },
            {
                "name": "Ye Yao",
                "org": "3Institute of Science and Technology for Brain Inspired Intelligence, Fudan University, Shanghai, PR China;"
            },
            {
                "name": "Zhaowen Liu",
                "org": "3Institute of Science and Technology for Brain Inspired Intelligence, Fudan University, Shanghai, PR China;"
            },
            {
                "name": "Zhaowen Liu",
                "org": "3Institute of Science and Technology for Brain Inspired Intelligence, Fudan University, Shanghai, PR China;"
            },
            {
                "name": "X Gong",
                "org": "11School of life science department, Fudan University, Shanghai, PR China;"
            },
            {
                "name": "Qiang Luo",
                "org": "3Institute of Science and Technology for Brain Inspired Intelligence, Fudan University, Shanghai, PR China;"
            },
            {
                "name": "Yanqing Tang",
                "org": "12Psychiatry department, The First Affiliated Hospital, China Medical University, Shenyang, Liaoning, PR China;"
            },
            {
                "name": "T J Crow",
                "org": ""
            },
            {
                "name": "Matthew R. Broome",
                "org": "Department of Psychiatry, Medical Science Division, University of Oxford, Oxford, UK;"
            },
            {
                "name": "Matthew R. Broome",
                "org": "Department of Psychiatry, Medical Science Division, University of Oxford, Oxford, UK;"
            },
            {
                "name": "Matthew R. Broome",
                "org": "Department of Psychiatry, Medical Science Division, University of Oxford, Oxford, UK;"
            },
            {
                "name": "Ke Xu",
                "org": "12Psychiatry department, The First Affiliated Hospital, China Medical University, Shenyang, Liaoning, PR China;"
            },
            {
                "name": "Chunbo Li",
                "org": ""
            },
            {
                "name": "Jijun Wang",
                "org": "17Shanghai Key Laboratory of Psychotic Disorders (No. 13dz2260500), Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China;"
            },
            {
                "name": "Guangming Lu",
                "org": "4Department of Medical Imaging, Jinling Hospital, Nanjing University School of Medicine, Nanjing, PR China;"
            },
            {
                "name": "Fei Wang",
                "org": ""
            },
            {
                "name": "Jianfeng Feng",
                "org": "3Institute of Science and Technology for Brain Inspired Intelligence, Fudan University, Shanghai, PR China;"
            }
        ],
        "venue": "Schizophrenia Bulletin",
        "year": 2016
    },
    "NCv0AwqG": {
        "id": "NCv0AwqG",
        "title": "Finding Communities by Their Centers.",
        "abstract": "Detecting communities or clusters in a real-world, networked system is of considerable interest in various fields such as sociology, biology, physics, engineering science, and interdisciplinary subjects, with significant efforts devoted in recent years. Many existing algorithms are only designed to identify the composition of communities, but not the structures. Whereas we believe that the local structures of communities can also shed important light on their detection. In this work, we develop a simple yet effective approach that simultaneously uncovers communities and their centers. The idea is based on the premise that organization of a community generally can be viewed as a high-density node surrounded by neighbors with lower densities, and community centers reside far apart from each other. We propose so-called \"community centrality\" to quantify likelihood of a node being the community centers in such a landscape, and then propagate multiple, significant center likelihood throughout the network via a diffusion process. Our approach is an efficient linear algorithm, and has demonstrated superior performance on a wide spectrum of synthetic and real world networks especially those with sparse connections amongst the community centers.",
        "keywords": "",
        "authors": [
            {
                "name": "Yan Chen",
                "org": "Center for Intelligent and Networked Systems, School of Computer Science, Southwest Petroleum University, Chengdu 610500, P.R. China."
            },
            {
                "name": "Pei Zhao",
                "org": "Center for Intelligent and Networked Systems, School of Computer Science, Southwest Petroleum University, Chengdu 610500, P.R. China."
            },
            {
                "name": "Ping Li",
                "org": "Center for Intelligent and Networked Systems, School of Computer Science, Southwest Petroleum University, Chengdu 610500, P.R. China."
            },
            {
                "name": "Kai Zhang",
                "org": "NEC Laboratories America, Inc. 4 Independence Way, Princeton, NJ 08540, USA."
            },
            {
                "name": "Jie Zhang",
                "org": "Center for Computational Systems Biology, Fudan University, Shanghai 200433, P. R. China."
            }
        ],
        "venue": "Scientific Reports",
        "year": 2016
    },
    "zOgtZdOA": {
        "id": "zOgtZdOA",
        "title": "Complex network inference from P300 signals: Decoding brain state under visual stimulus for able-bodied and disabled subjects",
        "abstract": "Distinguishing brain cognitive behavior underlying disabled and able-bodied subjects constitutes a challenging problem of significant importance. Complex network has established itself as a powerful tool for exploring functional brain networks, which sheds light on the inner workings of the human brain. Most existing works in constructing brain network focus on phase-synchronization measures between regional neural activities. In contrast, we propose a novel approach for inferring functional networks from P300 event-related potentials by integrating time and frequency domain information extracted from each channel signal, which we show to be efficient in subsequent pattern recognition. In particular, we construct brain network by regarding each channel signal as a node and determining the edges in terms of correlation of the extracted feature vectors. A six-choice P300 paradigm with six different images is used in testing our new approach, involving one able-bodied subject and three disabled subjects suffering from multiple sclerosis, cerebral palsy, traumatic brain and spinal-cord injury, respectively. We then exploit global efficiency, local efficiency and small-world indices from the derived brain networks to assess the network topological structure associated with different target images. The findings suggest that our method allows identifying brain cognitive behaviors related to visual stimulus between able-bodied and disabled subjects.",
        "keywords": "",
        "authors": [
            {
                "name": "Zhong-Ke Gao",
                "org": ""
            },
            {
                "name": "Qing Cai",
                "org": "School of Electrical Engineering and Automation, Tianjin University, Tianjin 300072, China"
            },
            {
                "name": "Na Dong",
                "org": "School of Electrical Engineering and Automation, Tianjin University, Tianjin 300072, China"
            },
            {
                "name": "Shan-Shan Zhang",
                "org": "School of Electrical Engineering and Automation, Tianjin University, Tianjin 300072, China"
            },
            {
                "name": "Yun Bo",
                "org": "School of Electrical Engineering and Automation, Tianjin University, Tianjin 300072, China"
            },
            {
                "name": "Jie Zhang",
                "org": "Center for Computational Systems Biology, Fudan University, Shanghai 200433, China"
            }
        ],
        "venue": "Physica A-statistical Mechanics and Its Applications",
        "year": 2016
    },
    "BLButzH3": {
        "id": "BLButzH3",
        "title": "Role of structural holes in containing spreading processes.",
        "abstract": "Structural holes are channels or paths spanned by a group of indirectly connected nodes and their intermediary in a network. In this work we emphasize the interesting role of structural holes as brokers for information propagation. Based on the distribution of the structural hole numbers associated with each node, we propose a simple yet effective approach for choosing the most influential nodes to immunize in containing the spreading processes. Using a wide spectrum of large real-world networks, we demonstrate that the proposed approach outperforms conventional methods in a remarkable way. In particular, we find that the performance gains of our approach are particularly prominent for networks with high transitivity and assortativity, which verifies the vital role of structural holes in information diffusion on networked systems.",
        "keywords": "",
        "authors": [
            {
                "name": "Ping Li",
                "org": ""
            },
            {
                "name": "Xian Sun",
                "org": ""
            },
            {
                "name": "Kai Zhang",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Jürgen Kurths",
                "org": ""
            }
        ],
        "venue": "Physical Review E",
        "year": 2016
    },
    "C1LeXl4C": {
        "id": "C1LeXl4C",
        "title": "An automated method for identifying an independent component analysis-based language-related resting-state network in brain tumor subjects for surgical planning.",
        "abstract": "As a noninvasive and \"task-free\" technique, resting-state functional magnetic resonance imaging (rs-fMRI) has been gradually applied to pre-surgical functional mapping. Independent component analysis (ICA)-based mapping has shown advantage, as no a priori information is required. We developed an automated method for identifying language network in brain tumor subjects using ICA on rs-fMRI. In addition to standard processing strategies, we applied a discriminability-index-based component identification algorithm to identify language networks in three different groups. The results from the training group were validated in an independent group of healthy human subjects. For the testing group, ICA and seed-based correlation were separately computed and the detected language networks were assessed by intra-operative stimulation mapping to verify reliability of application in the clinical setting. Individualized language network mapping could be automatically achieved for all subjects from the two healthy groups except one (19/20, success rate = 95.0%). In the testing group (brain tumor patients), the sensitivity of the language mapping result was 60.9%, which increased to 87.0% (superior to that of conventional seed-based correlation [47.8%]) after extending to a radius of 1 cm. We established an automatic and practical component identification method for rs-fMRI-based pre-surgical mapping and successfully applied it to brain tumor patients.",
        "keywords": "",
        "authors": [
            {
                "name": "Junfeng Lu",
                "org": "Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China."
            },
            {
                "name": "Han Zhang",
                "org": "Department of Radiology and Biomedical Research Imaging Center (BRIC), University of North Carolina at Chapel Hill, Chapel Hill, NC, USA."
            },
            {
                "name": "N U Farrukh Hameed",
                "org": "Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China."
            },
            {
                "name": "Jie Zhang",
                "org": "Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China."
            },
            {
                "name": "Shiwen Yuan",
                "org": "Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China."
            },
            {
                "name": "Tianming Qiu",
                "org": "Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China."
            },
            {
                "name": "Dinggang Shen",
                "org": "Department of Brain and Cognitive Engineering, Korea University, Seoul, 02841, Republic of Korea. dgshen@med.unc.edu."
            },
            {
                "name": "Jinsong Wu",
                "org": "Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China. wjsongc@126.com."
            }
        ],
        "venue": "Scientific reports",
        "year": 2017
    },
    "SpKmytaS": {
        "id": "SpKmytaS",
        "title": "Randomization or Condensation?: Linear-Cost Matrix Sketching Via Cascaded Compression Sampling.",
        "abstract": "Matrix sketching is aimed at finding compact representations of a matrix while simultaneously preserving most of its properties, which is a fundamental building block in modern scientific computing. Randomized algorithms represent state-of-the-art and have attracted huge interest from the fields of machine learning, data mining, and theoretic computer science. However, it still requires the use of the entire input matrix in producing desired factorizations, which can be a major computational and memory bottleneck in truly large problems. In this paper, we uncover an interesting theoretic connection between matrix low-rank decomposition and lossy signal compression, based on which a cascaded compression sampling framework is devised to approximate an m-by-n matrix in only O(m+n) time and space. Indeed, the proposed method accesses only a small number of matrix rows and columns, which significantly improves the memory footprint. Meanwhile, by sequentially teaming two rounds of approximation procedures and upgrading the sampling strategy from a uniform probability to more sophisticated, encoding-orientated sampling, significant algorithmic boosting is achieved to uncover more granular structures in the data. Empirical results on a wide spectrum of real-world, large-scale matrices show that by taking only linear time and space, the accuracy of our method rivals those state-of-the-art randomized algorithms consuming a quadratic, O(mn), amount of resources.\n\n",
        "keywords": "",
        "authors": [
            {
                "name": "Kai Zhang",
                "org": "Temple University, Philadelphia, PA, USA"
            },
            {
                "name": "Chuanren Liu",
                "org": "Drexel University, Philadelphia, PA, USA"
            },
            {
                "name": "Jie Zhang",
                "org": "Fudan University, Shanghai, China"
            },
            {
                "name": "Hui Xiong",
                "org": "Rutgers University, Newark, NJ, USA"
            },
            {
                "name": "Eric P. Xing",
                "org": "Carneigie Mellon University, Pittsburgh, PA, USA"
            },
            {
                "name": "Jieping Ye",
                "org": "University of Michigan, Ann Arbor, Ann Arbor, MI, USA"
            }
        ],
        "venue": "KDD '17: The 23rd ACM SIGKDD International Conference on Knowledge Discovery and Data Mining\n\t\t      Halifax\n\t\t      NS\n\t\t      Canada\n\t\t    August, 2017",
        "year": 2017
    },
    "GT9u5S5f": {
        "id": "GT9u5S5f",
        "title": "Multitarget search on complex networks: A logarithmic growth of global mean random cover time.",
        "abstract": "We investigate multitarget search on complex networks and derive an exact expression for the mean random cover time that quantifies the expected time a walker needs to visit multiple targets. Based on this, we recover and extend some interesting results of multitarget search on networks. Specifically, we observe the logarithmic increase of the global mean random cover time with the target number for a broad range of random search processes, including generic random walks, biased random walks, and maximal entropy random walks. We show that the logarithmic growth pattern is a universal feature of multi-target search on networks by using the annealed network approach and the Sherman-Morrison formula. Moreover, we find that for biased random walks, the global mean random cover time can be minimized, and that the corresponding optimal parameter also minimizes the global mean first passage time, pointing towards its robustness. Our findings further confirm that the logarithmic growth pattern is a universal law governing multitarget search in confined media.",
        "keywords": "",
        "authors": [
            {
                "name": "Tongfeng Weng",
                "org": "HKUST-DT System and Media Laboratory, Hong Kong University of Science and Technology, Kowloon, Hong Kong."
            },
            {
                "name": "Jie Zhang",
                "org": "Centre for Computational Systems Biology, Fudan University, Shanghai, China."
            },
            {
                "name": "Michael Small",
                "org": "The University of Western Australia, Crawley, WA 6009, Australia."
            },
            {
                "name": "Ji Yang",
                "org": "HKUST-DT System and Media Laboratory, Hong Kong University of Science and Technology, Kowloon, Hong Kong."
            },
            {
                "name": "Farshid Hassani Bijarbooneh",
                "org": "HKUST-DT System and Media Laboratory, Hong Kong University of Science and Technology, Kowloon, Hong Kong."
            },
            {
                "name": "Pan Hui",
                "org": "HKUST-DT System and Media Laboratory, Hong Kong University of Science and Technology, Kowloon, Hong Kong."
            }
        ],
        "venue": "Chaos (Woodbury, N.Y.)",
        "year": 2017
    },
    "HGuG2saU": {
        "id": "HGuG2saU",
        "title": "Functional connectivity decreases in autism in emotion, self, and face circuits identified by Knowledge-based Enrichment Analysis.",
        "abstract": "A powerful new method is described called Knowledge based functional connectivity Enrichment Analysis (KEA) for interpreting resting state functional connectivity, using circuits that are functionally identified using search terms with the Neurosynth database. The method derives its power by focusing on neural circuits, sets of brain regions that share a common biological function, instead of trying to interpret single functional connectivity links. This provides a novel way of investigating how task- or function-related networks have resting state functional connectivity differences in different psychiatric states, provides a new way to bridge the gap between task and resting-state functional networks, and potentially helps to identify brain networks that might be treated. The method was applied to interpreting functional connectivity differences in autism. Functional connectivity decreases at the network circuit level in 394 patients with autism compared with 473 controls were found in networks involving the orbitofrontal cortex, anterior cingulate cortex, middle temporal gyrus cortex, and the precuneus, in networks that are implicated in the sense of self, face processing, and theory of mind. The decreases were correlated with symptom severity.",
        "keywords": [
            "Autism spectrum disorder",
            "Neurosynth database",
            "Orbitofrontal cortex",
            "Precuneus",
            "Resting state fMRI"
        ],
        "authors": [
            {
                "name": "Wei Cheng",
                "org": "School of Mathematical Sciences and Centre for Computational Systems Biology, Fudan University, Shanghai 200433, PR China."
            },
            {
                "name": "Edmund T. Rolls",
                "org": "Department of Computer Science, University of Warwick, Coventry CV4 7AL, UK; Oxford Centre for Computational Neuroscience, Oxford, UK."
            },
            {
                "name": "Jie Zhang",
                "org": "School of Mathematical Sciences and Centre for Computational Systems Biology, Fudan University, Shanghai 200433, PR China."
            },
            {
                "name": "Wenbo Sheng",
                "org": "School of Mathematical Sciences and Centre for Computational Systems Biology, Fudan University, Shanghai 200433, PR China."
            },
            {
                "name": "Liang Ma",
                "org": "Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, PR China."
            },
            {
                "name": "Lin Wan",
                "org": "National Center of Mathematics and Interdisciplinary Sciences, Academy of Mathematics and Systems Science, Chinese Academy of Sciences, Beijing 100190, PR China."
            },
            {
                "name": "Qiang Luo",
                "org": "School of Mathematical Sciences and Centre for Computational Systems Biology, Fudan University, Shanghai 200433, PR China; School of Life Sciences, Fudan University, Shanghai 200433, PR China."
            },
            {
                "name": "Jianfeng Feng",
                "org": "School of Mathematical Sciences and Centre for Computational Systems Biology, Fudan University, Shanghai 200433, PR China; Department of Computer Science, University of Warwick, Coventry CV4 7AL, UK; School of Mathematical Sciences, School of Life Science and the Collaborative Innovation Center for Brain Science, Fudan University, Shanghai 200433, PR China. Electronic address: jianfeng.feng@warwick.ac.uk."
            }
        ],
        "venue": "NeuroImage",
        "year": 2017
    },
    "3pS4Bqbc": {
        "id": "3pS4Bqbc",
        "title": "Memory and betweenness preference in temporal networks induced from time series",
        "abstract": "A Nature Research Journal",
        "keywords": "",
        "authors": [
            {
                "name": "Tongfeng Weng",
                "org": "HKUST-DT System and Media Laboratory, Hong Kong University of Science and Technology, HongKong"
            },
            {
                "name": "Rui Zheng",
                "org": "HKUST-DT System and Media Laboratory, Hong Kong University of Science and Technology, HongKong"
            },
            {
                "name": "Pan Hui",
                "org": "HKUST-DT System and Media Laboratory, Hong Kong University of Science and Technology, HongKong"
            },
            {
                "name": "Jie Zhang",
                "org": "Centre for Computational Systems Biology, Fudan University, Shanghai, China"
            },
            {
                "name": "Michael Small",
                "org": "The University of Western Australia, Crawley, WA 6009, Australia"
            },
            {
                "name": "Michael Small",
                "org": "Mineral Resources, CSIRO, Kensington, WA, Australia"
            }
        ],
        "venue": "Scientific Reports",
        "year": 2017
    },
    "pqiKGNhK": {
        "id": "pqiKGNhK",
        "title": "Hunting for a moving target on a complex network",
        "abstract": "Random searching for a mobile target is frequently encountered in many real situations, posing great challenges for theoretical analysis which traditionally deals only with static targets. We investigate mobile-object search on networks in which the targetu0027s location is changing with time. We adopt mean first-encounter time to quantify the search time a searcher takes to capture a time-moving target and derive its analytical expression, when it exists. Interestingly, we observe an entirely distinct behavior for a mobile-object search compared to traditional results with a static target. Counter-intuitively, we find that compared with searching for a static target, a mobile object is easier to be captured under the same circumstances. Furthermore, we demonstrate that staying at the hub node is the optimal strategy for hunting for a mobile object on a heterogeneous network. Our findings reveal distinct effects for a mobile object on both search and transport.",
        "keywords": "",
        "authors": [
            {
                "name": "Tongfeng Weng",
                "org": "HKUST-DT System and Media Laboratory, Hong Kong University of Science and Technology 999077, Hong Kong"
            },
            {
                "name": "Jie Zhang",
                "org": "Institute of Science and Technology for Brain-Inspired Intellegence, Fudan University - Shanghai 200433, China"
            },
            {
                "name": "Michael Small",
                "org": "The University of Western Australia - Crawley, WA 6009, Australia"
            },
            {
                "name": "Michael Small",
                "org": "The University of Western Australia - Crawley, WA 6009, Australia"
            },
            {
                "name": "Pan Hui",
                "org": "HKUST-DT System and Media Laboratory, Hong Kong University of Science and Technology 999077, Hong Kong"
            }
        ],
        "venue": "EPL",
        "year": 2017
    },
    "4uGzLeO0": {
        "id": "4uGzLeO0",
        "title": "The functional and genetic associations of neuroimaging data: a toolbox",
        "abstract": "Advances in neuroimaging and sequencing techniques provide an unprecedented opportunity to map the function of brain regions and to identify the roots of psychiatric diseases. However, the results generated by most neuroimaging studies, i.e., activated clusters/regions or functional connectivities between brain regions, frequently cannot be conveniently and systematically interpreted, rendering the biological meaning unclear. We describe a Brain Annotation Toolbox (BAT), a toolbox that helps to generate functional and genetic annotations for neuroimaging results. The toolbox can take data from brain regions identified with an atlas, or from brain regions identified as activated in tasks, or from functional connectivity links or networks of links. Then, the voxel-level functional description from the Neurosynth database and the gene expression profile from the Allen Brain Atlas are used to generate functional and genetic knowledge for such region-level data. Parametric (Fisher9s exact test) or non-parametric (permutation test) statistical tests are adopted to identify significantly related functional descriptors and genes for the neuroimaging results. The validity of the approach is demonstrated by showing that the functional and genetic annotations for specific brain regions are consistent with each other; and further the region by region functional similarity network and gene co-expression networks are highly correlated for many major brain atlases. One application of BAT is to help provide functional and genetic annotations for the newly discovered regions with unknown functions, e.g., the 97 new regions identified in the Human Connectome Project. Importantly too, this toolbox can help understand differences between patients with psychiatric disorders and controls, and this is demonstrated using data for schizophrenia and autism, for which the functional and genetic annotations for the neuroimaging data differences between patients and controls are consistent with each other and help with the interpretation of the differences.",
        "keywords": "",
        "authors": [
            {
                "name": "Zhaowen Liu",
                "org": "Xidian University;"
            },
            {
                "name": "Edmund T. Rolls",
                "org": "University of Warwick;"
            },
            {
                "name": "Jie Zhang",
                "org": "Fudan University;"
            },
            {
                "name": "Ming Yang",
                "org": "Fudan University;"
            },
            {
                "name": "Jingnan Du",
                "org": "Fudan University;"
            },
            {
                "name": "Weikang Gong",
                "org": "Fudan University;"
            },
            {
                "name": "Wei Cheng",
                "org": "Fudan University;"
            },
            {
                "name": "He Wang",
                "org": "Fudan University;"
            },
            {
                "name": "Kamil Ugurbil",
                "org": "University of Minnesota"
            },
            {
                "name": "Jianfeng Feng",
                "org": "Fudan University;"
            }
        ],
        "venue": "bioRxiv",
        "year": 2017
    },
    "EknkFPKn": {
        "id": "EknkFPKn",
        "title": "Multiple random walks on complex networks: A harmonic law predicts search time.",
        "abstract": "We investigate multiple random walks traversing independently and concurrently on complex networks and introduce the concept of mean first parallel passage time (MFPPT) to quantify their search efficiency. The mean first parallel passage time represents the expected time required to find a given target by one or some of the multiple walkers. We develop a general theory that allows us to calculate the MFPPT analytically. Interestingly, we find that the global MFPPT follows a harmonic law with respect to the global mean first passage times of the associated walkers. Remarkably, when the properties of multiple walkers are identical, the global MFPPT decays in a power law manner with an exponent of unity, irrespective of network structure. These findings are confirmed by numerical and theoretical results on various synthetic and real networks. The harmonic law reveals a universal principle governing multiple random walks on networks that uncovers the contribution and role of the combined walkers in a target search. Our paradigm is also applicable to a broad range of random search processes.",
        "keywords": "",
        "authors": [
            {
                "name": "Tongfeng Weng",
                "org": "HKUST-DT System and Media Laboratory, Hong Kong University of Science and Technology, 999077, Hong Kong."
            },
            {
                "name": "Jie Zhang",
                "org": "Centre for Computational Systems Biology, Fudan University, Shanghai 200433, China."
            },
            {
                "name": "Michael Small",
                "org": "University of Western Australia, Crawley, Western Australia 6009, Australia."
            },
            {
                "name": "Pan Hui",
                "org": "HKUST-DT System and Media Laboratory, Hong Kong University of Science and Technology, 999077, Hong Kong."
            }
        ],
        "venue": "Physical review. E",
        "year": 2017
    },
    "g6T40pxY": {
        "id": "g6T40pxY",
        "title": "Partial cover time that is sublinear in the number of targets on complex networks: a universal law.",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Tongfeng Weng",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Michael Small",
                "org": ""
            },
            {
                "name": "Farshid Hassani Bijarbooneh",
                "org": ""
            },
            {
                "name": "Pan Hui",
                "org": ""
            }
        ],
        "venue": "CoRR",
        "year": 2017
    },
    "A9KKbdZR": {
        "id": "A9KKbdZR",
        "title": "Awake Transcortical Approach Resection of Dominant Posterior Cingulate Gyrus Glioma: 2-Dimensional Operative Video.",
        "abstract": "Two techniques, the translongitudinal cerebral fissure and transfrontal cortical approach, can be employed to resect posterior cingulate gyrus tumors. We demonstrate the transcortical technique comprising of multimodal imaging guidance and awake brain mapping which enabled maximum safe resection of dominant cingulate gyrus glioma. The patient, a 49-yr-old female, came to clinic after experiencing headache for a month. Initial magnetic resonance imaging (MRI) scans revealed a nonenhancing lesion of the left posterior cingulate gyrus. Three-dimensional magnetic resonance spectroscopy was used to analyze the choline/N-acetyl-aspartate index (CNI) which strongly suggested a low-grade glioma diagnosis. In surgery, after creating a tailed bone window and dural opening, strip electrode was placed across the central sulcus for continuous motor evoked potential monitoring. Next, direct cortical stimulation was done to map functional cortical areas. The transcortical approach was chosen at this point because many veins hindered hemisphere retraction. Noneloquent cortical incisions were made and the tumor was carefully debunked with a cavitron ultrasonic surgical aspirator. The corpus callosum marked the deep end of dissection. Subcortical mapping combined with diffusion tensor imaging tractography-based navigation was performed to localize motor and language tracks. Intraoperative MRI evaluation confirmed a gross total resection. Pathological and molecular analysis revealed a World Health Organization Grade II IDH-wildtype Diffuse Astrocytoma diagnosis. Since the patient falls in high-risk group, she was also administered radiation and chemotherapy. Long-term cognitive evaluation follow-up of the patient showed she had good functional recovery with no obvious long-term deficits. Informed patient consent was obtained.",
        "keywords": "",
        "authors": [
            {
                "name": "N U Farrukh Hameed",
                "org": "Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China."
            },
            {
                "name": "Bin Wu",
                "org": "Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China."
            },
            {
                "name": "Fangyuan Gong",
                "org": "Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China."
            },
            {
                "name": "Jie Zhang",
                "org": "Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China."
            },
            {
                "name": "Hong Chen",
                "org": "Department of Pathology, Huashan Hospital, Fudan University, Shanghai, China."
            },
            {
                "name": "Jinsong Wu",
                "org": "Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China."
            }
        ],
        "venue": "Operative neurosurgery (Hagerstown, Md.)",
        "year": 2018
    },
    "Wu5ot2zM": {
        "id": "Wu5ot2zM",
        "title": "Universal principles governing multiple random searchers on complex networks: The logarithmic growth pattern and the harmonic law.",
        "abstract": "We propose a unified framework to evaluate and quantify the search time of multiple random searchers traversing independently and concurrently on complex networks. We find that the intriguing behaviors of multiple random searchers are governed by two basic principles-the logarithmic growth pattern and the harmonic law. Specifically, the logarithmic growth pattern characterizes how the search time increases with the number of targets, while the harmonic law explores how the search time of multiple random searchers varies relative to that needed by individual searchers. Numerical and theoretical results demonstrate these two universal principles established across a broad range of random search processes, including generic random walks, maximal entropy random walks, intermittent strategies, and persistent random walks. Our results reveal two fundamental principles governing the search time of multiple random searchers, which are expected to facilitate investigation of diverse dynamical processes like synchronization and spreading.",
        "keywords": "",
        "authors": [
            {
                "name": "Tongfeng Weng",
                "org": "HKUST-DT System and Media Laboratory, Hong Kong University of Science and Technology, Hong Kong."
            },
            {
                "name": "Jie Zhang",
                "org": "Centre for Computational Systems Biology, Fudan University, China."
            },
            {
                "name": "Michael Small",
                "org": "Mineral Resources, CSIRO, Kensington, Western Australia, Australia."
            },
            {
                "name": "Bahareh Harandizadeh",
                "org": "HKUST-DT System and Media Laboratory, Hong Kong University of Science and Technology, Hong Kong."
            },
            {
                "name": "Pan Hui",
                "org": "HKUST-DT System and Media Laboratory, Hong Kong University of Science and Technology, Hong Kong."
            }
        ],
        "venue": "Physical review. E",
        "year": 2018
    },
    "wLQ4eA8b": {
        "id": "wLQ4eA8b",
        "title": "Functional Connectivity of the Anterior Cingulate Cortex in Depression and in Health.",
        "abstract": "The first voxel-level resting-state functional connectivity (FC) neuroimaging analysis of depression of the anterior cingulate cortex (ACC) showed in 282 patients with major depressive disorder compared with 254 controls, some higher, and some lower FCs. However, in 125 unmedicated patients, primarily increases of FC were found: of the subcallosal anterior cingulate with the lateral orbitofrontal cortex, of the pregenual/supracallosal anterior cingulate with the medial orbitofrontal cortex, and of parts of the anterior cingulate with the inferior frontal gyrus, superior parietal lobule, and with early cortical visual areas. In the 157 medicated patients, these and other FCs were lower than in the unmedicated group. Parcellation was performed based on the FC of individual ACC voxels in healthy controls. A pregenual subdivision had high FC with medial orbitofrontal cortex areas, and a supracallosal subdivision had high FC with lateral orbitofrontal cortex and inferior frontal gyrus. The high FC in depression between the lateral orbitofrontal cortex and the subcallosal parts of the ACC provides a mechanism for more non-reward information transmission to the ACC, contributing to depression. The high FC between the medial orbitofrontal cortex and supracallosal ACC in depression may also contribute to depressive symptoms.",
        "keywords": "",
        "authors": [
            {
                "name": "Edmund T Rolls",
                "org": "Oxford Centre for Computational Neuroscience, Oxford, UK."
            },
            {
                "name": "Wei Cheng",
                "org": "Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China."
            },
            {
                "name": "Weikang Gong",
                "org": "Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China."
            },
            {
                "name": "Jiang Qiu",
                "org": "Department of Psychology, Southwest University, Chongqing, China."
            },
            {
                "name": "Chanjuan Zhou",
                "org": "Department of Neurology, Yongchuan Hospital of Chongqing Medical University, Chongqing, China."
            },
            {
                "name": "Jie Zhang",
                "org": "Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China."
            },
            {
                "name": "Wujun Lv",
                "org": "School of Mathematics, Shanghai University Finance and Economics, Shanghai, PR China."
            },
            {
                "name": "Hongtao Ruan",
                "org": "School of Mathematical Sciences, School of Life Science and the Collaborative Innovation Center for Brain Science, Fudan University, Shanghai, PR China."
            },
            {
                "name": "Dongtao Wei",
                "org": "Department of Psychology, Southwest University, Chongqing, China."
            },
            {
                "name": "Ke Cheng",
                "org": "College of Basic Medical Sciences, Chongqing Medical University, Chongqing, China."
            },
            {
                "name": "Jie Meng",
                "org": "Department of Psychology, Southwest University, Chongqing, China."
            },
            {
                "name": "Peng Xie",
                "org": "Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China."
            },
            {
                "name": "Jianfeng Feng",
                "org": "School of Mathematical Sciences, School of Life Science and the Collaborative Innovation Center for Brain Science, Fudan University, Shanghai, PR China."
            }
        ],
        "venue": "Cerebral cortex (New York, N.Y. : 1991)",
        "year": 2018
    },
    "A8mEBd9J": {
        "id": "A8mEBd9J",
        "title": "\"Brain Connectivity Deviates by Sex and Hemisphere in the First Episode of Schizophrenia\"-A Route to the Genetic Basis of Language and Psychosis?",
        "abstract": "Schizophrenia is genetic in origin and associated with a fecundity disadvantage. The deficits in schizophrenia have been attributed to variation related to the human capacity for language or brain laterality. How sex influences the relative connectivity of the 2 hemispheres is a route to understanding these 2 functions. Using resting-state functional magnetic resonance imaging (fMRI) we searched for sex- and hemisphere-specific changes in whole-brain functional-connectivity in multi-site datasets (altogether 672 subjects including 286 patients, all right-handed) in the first-episode schizophrenia (illness duration ≤ 1 year, mostly drug naive) and in chronic stages of schizophrenia (illness duration > 1 year), respectively. We used meta-analyses to integrate data from different sources concerning individuals at the same illness stage. We found first-episode male patients are predominantly left-lateralized in aberrant connectivity with a focus on Broca's area. Female patients show a lesser degree of lateralization than males, but to the right particularly in orbital frontal cortex. In the chronic stage, the focus of aberrant connectivity shifted from anterior to posterior structures with prominent involvement of the thalamus and pre- and post-central gyri bilaterally and in both sexes. While the \"deviant connectivity\" is right-sided in both the first-episode and the chronic stages in females, in males there is a shift between stages from the left to the right hemisphere. We hypothesized that the pathophysiology of schizophrenia may lie in the interaction between sex and lateralization, ie, in genetic mechanisms located on the X and Y chromosomes, intrinsic to the evolution of language.",
        "keywords": "",
        "authors": [
            {
                "name": "Qiang Wang",
                "org": "West China Brain Research Center, West China Hospital of Sichuan University, Chengdu, PR China."
            },
            {
                "name": "Jie Zhang",
                "org": "Key Laboratory of Computational Neuroscience and BrainInspired Intelligence (Fudan University), Ministry of Education, PR China."
            },
            {
                "name": "Zhaowen Liu",
                "org": "School of Computer Science and Technology, Xidian University, Xi'an, PR China."
            },
            {
                "name": "Tim J Crow",
                "org": "POWIC, University Department of Psychiatry, Warneford Hospital, Oxford, UK."
            },
            {
                "name": "Kai Zhang",
                "org": "Department of Computer and Information Sciences, Temple University, Philadelphia, PA."
            },
            {
                "name": "Mingli Li",
                "org": "West China Brain Research Center, West China Hospital of Sichuan University, Chengdu, PR China."
            },
            {
                "name": "Liansheng Zhao",
                "org": "West China Brain Research Center, West China Hospital of Sichuan University, Chengdu, PR China."
            },
            {
                "name": "Xiaojing Li",
                "org": "West China Brain Research Center, West China Hospital of Sichuan University, Chengdu, PR China."
            },
            {
                "name": "Wei Deng",
                "org": "West China Brain Research Center, West China Hospital of Sichuan University, Chengdu, PR China."
            },
            {
                "name": "Wanjun Guo",
                "org": "West China Brain Research Center, West China Hospital of Sichuan University, Chengdu, PR China."
            },
            {
                "name": "Xiaohong Ma",
                "org": "West China Brain Research Center, West China Hospital of Sichuan University, Chengdu, PR China."
            },
            {
                "name": "Wei Cheng",
                "org": "Key Laboratory of Computational Neuroscience and BrainInspired Intelligence (Fudan University), Ministry of Education, PR China."
            },
            {
                "name": "Liang Ma",
                "org": "Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, PR China."
            },
            {
                "name": "Lin Wan",
                "org": "Interdisciplinary Sciences, Academy of Mathematics and Systems Science, Chinese Academy of Sciences, Beijing, PR China."
            },
            {
                "name": "Guangming Lu",
                "org": "Department of Medical Imaging, Jinling Hospital, Nanjing University School of Medicine, Nanjing, PR China."
            },
            {
                "name": "Zhening Liu",
                "org": "Mental Health Center, Xiangya Hospital, Central South University, Changsha, PR China."
            },
            {
                "name": "Jijun Wang",
                "org": "Shanghai Key Laboratory of Psychotic Disorders (No. 13dz2260500), Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China."
            },
            {
                "name": "Jianfeng Feng",
                "org": "Zhongshan Hospital, Fudan University, Shanghai, PR China."
            },
            {
                "name": "Tao Li",
                "org": "West China Brain Research Center, West China Hospital of Sichuan University, Chengdu, PR China."
            }
        ],
        "venue": "Schizophrenia bulletin",
        "year": 2018
    },
    "rnqIxuY7": {
        "id": "rnqIxuY7",
        "title": "Predicting search time when hunting for multiple moving targets: A recursive harmonic law.",
        "abstract": "We investigate searching for multiple mobile objects on networks and introduce the concept of mean random search time (MRST) to quantify the expected time a searcher takes to capture moving targets specified in advance. We consider this quantity averaged over all initial conditions for a searcher and multiple targets called the global MRST. We find that the growth of global MRST follows a recursive harmonic law with respect to that of stalking the individuals. In particular, when the diffusive laws of moving targets are identical, the global MRST shows a logarithmic increase with the number of moving targets. Moreover, utilizing the recursive harmonic law, we can accurately predict the expected successive time interval for capturing a new moving target. The recursive harmonic law unveils the underlying mechanism governing the search time when hunting for multiple moving targets on networks.",
        "keywords": "",
        "authors": [
            {
                "name": "Tongfeng Weng",
                "org": "Business School, University of Shanghai for Science and Technology, Shanghai 200093, People's Republic of China."
            },
            {
                "name": "Jie Zhang",
                "org": "Centre for Computational Systems Biology, Fudan University, Shanghai 200093, People's Republic of China."
            },
            {
                "name": "Michael Small",
                "org": "School of Mathematics and Statistics, The University of Western Australia, Crawley, Western Australia 6009, Australia."
            },
            {
                "name": "Huijie Yang",
                "org": "Business School, University of Shanghai for Science and Technology, Shanghai 200093, People's Republic of China."
            },
            {
                "name": "Pan Hui",
                "org": "HKUST-DT System and Media Laboratory, Hong Kong University of Science and Technology, Hong Kong 999077."
            }
        ],
        "venue": "Chaos (Woodbury, N.Y.)",
        "year": 2018
    },
    "388KCcQx": {
        "id": "388KCcQx",
        "title": "Comparison of voltammetric data obtained for the trans-[Mn(CN)(CO)2[P(OPh)3](Ph2PCH2PPh2)]0/+ process in BMIM.PF6 ionic liquid under microchemical and conventional conditions.",
        "abstract": "Conventional cyclic voltammetric studies on the oxidation of millimolar concentrations (mg masses) of trans-[Mn(CN)(CO)(2)[P(OPh)(3)](Ph(2)PCH(2)PPh(2))] (trans-Mn) dissolved in milliliter volumes of bulk ionic liquid, 1-butyl-3-methylimidazolium hexafluorophosphate (BMIM.PF(6)), give rise to a reversible [trans-Mn](0/+) process. In this study, it is shown that equally well-defined reversible voltammetry can be more economically obtained under microchemical ionic liquid conditions by employing a chemically modified electrode (microg quantities of trans-Mn adhered to a glassy carbon electrode covered with microliter volumes of water-immiscible BMIM.PF(6)) in contact with aqueous (0.1 M KPF(6)) electrolyte. The ability to obtain electrochemical data that are directly relatable to bulk ionic liquid media under these microchemical conditions is principally associated with the dissolution of electrogenerated solid [trans-Mn](+) in the layer of water-immiscible BMIM.PF(6) present at the electrode/ionic liquid/aqueous electrolyte interface. If the BMIM.PF(6) layer is sufficiently thick, mass transport of the dissolved species is governed by semi-infinite linear diffusion. Under these conditions, the voltammetric waveshape and position, but not the current magnitude are the same as those found when conventional bulk ionic liquid conditions are employed. In contrast, use of very thin layers produces voltammograms that exhibit the characteristics expected for a reversible process in which the mass transport process is predominantly governed by finite rather than semi-infinite diffusion. A theoretical model has been developed that describes the transformation from thick- to thin-layer type behavior as the thickness of the ionic liquid layer is decreased.",
        "keywords": [
            "ionic liquid"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "School of Chemistry, Monash University, P.O. Box 23, Clayton, Victoria 3800, Australia."
            },
            {
                "name": "Alan M Bond",
                "org": ""
            }
        ],
        "venue": "Analytical chemistry",
        "year": 2003
    },
    "EJy6CGph": {
        "id": "EJy6CGph",
        "title": "Conditions required to achieve the apparent equivalence of adhered solid- and solution-phase voltammetry for ferrocene and other redox-active solids in ionic liquids.",
        "abstract": "The voltammetry of ferrocene (Fc) and Fc+ in the room-temperature ionic liquid, 1-butyl-3-methylimidazolium hexafluorophosphate (BMIM x PF6) has been studied when solid is adhered to glassy carbon or platinum disk electrodes. Due to the slow dissolution kinetics and small diffusion coefficients in the viscous BMIM x PF6 ionic liquid, it is possible to obtain voltammograms of adhered Fc or Fc+ solid that are essentially indistinguishable (except for the current magnitude) from the reversible solution-phase Fc(0/+) process widely employed to provide a reference potential scale. However, the nature of the voltammetry obtained from the adhered solid is governed by the thickness (mass of the solid) of the particle layer. The mechanism proposed to explain the equivalence to solution-phase data involves dissolution at the particle/ionic liquid interface and is supported by electrochemical quartz microbalance measurements and a numerical simulation. Extensive studies on other redox-active solids suggest that voltammograms of solid particles adhered to the electrode surface in contact with ionic liquids frequently exhibit classical behavior associated with solution-phase diffusion-controlled voltammetry. Consequently, the method of adhering microparticles onto an electrode surface can frequently provide an efficient method of establishing ionic liquid solution-phase redox data using extremely small quantities of solid.",
        "keywords": [
            "ionic liquid"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Alan M Bond",
                "org": ""
            }
        ],
        "venue": "Analytical chemistry",
        "year": 2003
    },
    "qyn61pdD": {
        "id": "qyn61pdD",
        "title": "Electrochemical Studies on the Modular Podand 1,3,5-Tris(3-((ferrocenylmethyl)amino)pyridiniumyl)-2,4,6-triethylbenzene Hexafluorophosphate in Conventional Solvents and Ionic Liquids",
        "abstract": "",
        "keywords": [
            "ionic liquid"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Alan M. Bond",
                "org": ""
            },
            {
                "name": "Warwick J. Belcher",
                "org": ""
            },
            {
                "name": "Karl J. Wallace",
                "org": ""
            },
            {
                "name": "Jonathan W. Steed",
                "org": ""
            }
        ],
        "venue": "Journal of Physical Chemistry B",
        "year": 2003
    },
    "Og9SsLyP": {
        "id": "Og9SsLyP",
        "title": "Voltammetric Reduction of<i>α</i>- and<i>γ</i>*-[S<sub>2</sub>W<sub>18</sub>O<sub>62</sub>]<sup>4</sup><sup>-</sup>and α-, β-, and γ-[SiW<sub>12</sub>O<sub>40</sub>]<sup>4</sup><sup>-</sup>:  Isomeric Dependence of Reversible Potentials of Polyoxometalate Anions Using Data Obtained by Novel Dissolution and Conventional Solution-Phase Processes",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Alan M. Bond",
                "org": ""
            },
            {
                "name": "Peter J. S. Richardt",
                "org": ""
            },
            {
                "name": "Anthony G. Wedd",
                "org": ""
            }
        ],
        "venue": "Inorganic Chemistry",
        "year": 2004
    },
    "Np9q3QKu": {
        "id": "Np9q3QKu",
        "title": "Voltammetric Studies with Adhered Microparticles and the Detection of a Dependence of Organometallic Cis<sup>+</sup>→ Trans<sup>+</sup>First-Order Isomerization Rate Constants on the Identity of the Ionic Liquid",
        "abstract": "",
        "keywords": [
            "first order",
            "rate constant",
            "ionic liquid"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Alan M. Bond",
                "org": ""
            }
        ],
        "venue": "Journal of Physical Chemistry B",
        "year": 2004
    },
    "3NF1eWKA": {
        "id": "3NF1eWKA",
        "title": "Resistance, capacitance, and electrode kinetic effects in Fourier-transformed large-amplitude sinusoidal voltammetry: emergence of powerful and intuitively obvious tools for recognition of patterns of behavior.",
        "abstract": "Large-amplitude sinusoidal ac voltammetric techniques, when analyzed in the frequency domain using the Fourier transform-inverse Fourier transform sequence, produce the expected dc and fundamental harmonic ac responses in addition to very substantial second, third, and higher ac harmonics that arise from the presence of significant nonlinearity. A full numerical simulation of the process, Red right arrow over left arrow Ox + e(-), incorporates terms for the uncompensated resistance (R(u)), capacitance of the double layer (C(dl)), and slow electron transfer kinetics (in particular, the reversible potential (E degrees ), rate constant (k(0)), and charge transfer coefficient (alpha) from the Butler-Volmer model). Identification of intuitively obvious patterns of behavior (with characteristically different sensitivity regimes) in dc, fundamental, and higher harmonic terms enables simple protocols to be developed to estimate R(u), C(dl), E degrees , k(0), and alpha. Thus, if large-amplitude sinusoidal cyclic voltammograms are obtained for two concentrations of the reduced species, data obtained from analysis of the recovered signals provide initial estimates of parameters as follows: (a) the dc cyclic component provides an estimate of E degrees (because the R(u) and k(0) effects are minimized); (b) the fundamental harmonic provides an estimate of C(dl) (because it has a high capacitance-to-faradaic current ratio); and (c) the second harmonic provides an estimate of R(u), k(0), and alpha (because the C(dl) effect is minimized). Methods of refining the initial estimates are then implemented. As a check on the fidelity of the parameters (estimated on the basis of an essentially heuristic approach that solely utilizes the dc, fundamental, and second harmonic voltammograms), comparison of the predicted simulated and experimental third (or higher) harmonic voltammograms can be made to verify that agreement between theory and experiment has been achieved at a predetermined level. The use of the heuristic pattern recognition approach to evaluate the oxidation of ferrocene at a platinum electrode (a reversible process) in the very high resistance solvent dichloromethane (0.1 M Bu(4)NPF(6)) and the reduction of [Fe(CN(6))](3)(-) at a glassy carbon electrode (a quasi-reversible process) in much lower resistance but higher capacitance conditions found in aqueous (0.5 M KCl) media is described and verifies the inherent advantages of employing large-amplitude sinusoidal techniques in quantitative studies of electrode processes.",
        "keywords": [
            "fourier transform",
            "kinetics"
        ],
        "authors": [
            {
                "name": "Anna A. Sher",
                "org": "Oxford University Computing Laboratory, Wolfson Building, Parks Road, Oxford, OX1 3QD, United Kingdom."
            },
            {
                "name": "Alan M. Bond",
                "org": ""
            },
            {
                "name": "David J. Gavaghan",
                "org": ""
            },
            {
                "name": "Kathryn Harriman",
                "org": ""
            },
            {
                "name": "Stephen W. Feldberg",
                "org": ""
            },
            {
                "name": "Noel W. Duffy",
                "org": ""
            },
            {
                "name": "Si-Xuan Guo",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            }
        ],
        "venue": "Analytical chemistry",
        "year": 2004
    },
    "ibXoUDib": {
        "id": "ibXoUDib",
        "title": "Large-amplitude Fourier transformed high-harmonic alternating current cyclic voltammetry: kinetic discrimination of interfering Faradaic processes at glassy carbon and at boron-doped diamond electrodes.",
        "abstract": "Significant advantages of Fourier transformed large-amplitude ac higher (second to eighth) harmonics relative to responses obtained with conventional small-amplitude ac or dc cyclic voltammetric methods have been demonstrated with respect to (i) the suppression of capacitive background currents, (ii) the separation of the reversible reduction of [Ru(NH(3))(6)](3+) from the overlapping irreversible oxygen reduction process under conditions where aerobic oxygen remains present in the electrochemical cell, and (iii) the kinetic resolution of the reversible [Ru(NH(3))(6)](3+/2+) process in mixtures of [Fe(CN)(6)](3-) and [Ru(NH(3))(6)](3+) at appropriately treated boron-doped diamond electrodes, even when highly unfavorable [Fe(CN)(6)](3-) to [Ru(NH(3))(6)](3+) concentration ratios are employed. Theoretical support for the basis of kinetic discrimination in large-amplitude higher harmonic ac cyclic voltammetry is provided.",
        "keywords": [
            "kinetics",
            "fourier transform"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "School of Chemistry, Monash University, Clayton, Victoria 3800, Australia."
            },
            {
                "name": "Si-Xuan Guo",
                "org": ""
            },
            {
                "name": "Alan M Bond",
                "org": ""
            },
            {
                "name": "Frank Marken",
                "org": ""
            }
        ],
        "venue": "Analytical chemistry",
        "year": 2004
    },
    "zclumn9S": {
        "id": "zclumn9S",
        "title": "Resistance, Capacitance, and Electrode Kinetic Effects in Fourier-Transformed Large-Amplitude sinusoidal Voltammetry: Emergence of Powerful and Intuitively Obvious Tools for",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "noel w duffy",
                "org": ""
            },
            {
                "name": "kathryn harriman",
                "org": ""
            },
            {
                "name": "alan m bond",
                "org": ""
            },
            {
                "name": "anna a sher",
                "org": ""
            },
            {
                "name": "stephen w feldberg",
                "org": ""
            },
            {
                "name": "david j gavaghan",
                "org": ""
            },
            {
                "name": "sixuan guo",
                "org": ""
            }
        ],
        "venue": "Analytical Chemistry",
        "year": 2004
    },
    "mNYKEYE0": {
        "id": "mNYKEYE0",
        "title": "Novel kinetic and background current selectivity in the even harmonic components of fourier transformed square-wave voltammograms of surface-confined azurin.",
        "abstract": "Fourier transform analysis of ramped square-wave voltammograms indicates the availability of a novel form of kinetic selectivity for surface-confined electron-transfer processes. Thus, for all the even harmonic components, quasi-reversible processes are sensitive to the surface coverage, the reversible potential, the electron-transfer rate constant (k(0')), and the electron-transfer coefficient (alpha), as well as to the amplitude (DeltaE) and frequency (f) of the square wave and dc scan rate. Additionally, it is insensitive to background capacitance current. In contrast, reversible processes and background currents are predicted to be absent from the even harmonics and only detectable in the odd harmonic components. The square-wave voltammetry of the surface-confined quasi-reversible azurin process azurin[Cu(II)] + e(-) right arrow over left arrow azurin[Cu(I)] at a paraffin-impregnated graphite electrode has been employed as a model system to test theoretical predictions. Most voltammetric characteristics of the even harmonic components obtained from the Fourier analysis are consistent with electrode kinetic values of k(0') = 90 s(-1) and alpha = 0.48, although some nonideality possibly due to kinetic dispersion also is apparent. Conditions also have been determined under which a readily generated waveform constructed from the Fourier series of sine waves produces voltammograms that are essentially indistinguishable from those predicted when an ideal square wave is employed.",
        "keywords": [
            "fourier transform",
            "kinetics"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Si-Xuan Guo",
                "org": ""
            },
            {
                "name": "Alan M Bond",
                "org": ""
            },
            {
                "name": "Michael J Honeychurch",
                "org": ""
            },
            {
                "name": "Keith B Oldham",
                "org": ""
            }
        ],
        "venue": "The journal of physical chemistry. B",
        "year": 2005
    },
    "2Yx2jh0J": {
        "id": "2Yx2jh0J",
        "title": "Practical considerations associated with voltammetric studies in room temperature ionic liquids.",
        "abstract": "Recent developments associated with voltammetric studies in ionic liquid media have been critically reviewed. Initially, advantageous electrochemical properties of ionic liquids are summarised, as are limitations encountered by the presence of impurities and problems related to purification and recovery of ionic liquids. Subsequently, the use of IUPAC recommended ferrocene oxidation and cobalticenium reduction processes as potential reference scales in ionic liquids and the application of voltammetry of adhered solid and microchemical approaches to the measurement of formal potentials and kinetics of coupled first order chemical reactions are discussed. Finally, the possible use of volatile ionic liquids is considered as an alternative to use of the non-volatile ionic liquids media, presently emphasized in most studies.",
        "keywords": [],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "monash university clayton campus"
            },
            {
                "name": "Alan M Bond",
                "org": "monash university clayton campus"
            }
        ],
        "venue": "The Analyst",
        "year": 2005
    },
    "z9RRdpaF": {
        "id": "z9RRdpaF",
        "title": "Fourier Transformed Large Amplitude Square-Wave Voltammetry as an Alternative to Impedance Spectroscopy: Evaluation of Resistance, Capacitance and Electrode Kinetic Effects via an Heuristic Approach",
        "abstract": "",
        "keywords": [
            "fourier transform",
            "pattern recognition",
            "kinetics",
            "impedance spectroscopy"
        ],
        "authors": [
            {
                "name": "Anna A. Sher",
                "org": ""
            },
            {
                "name": "Alan M. Bond",
                "org": ""
            },
            {
                "name": "David J. Gavaghan",
                "org": ""
            },
            {
                "name": "Kathryn Gillow",
                "org": ""
            },
            {
                "name": "Noel W. Duffy",
                "org": ""
            },
            {
                "name": "Si-Xuan Guo",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            }
        ],
        "venue": "Electroanalysis",
        "year": 2005
    },
    "kQicZWya": {
        "id": "kQicZWya",
        "title": "Voltammetric studies of polyoxometalate microparticles in contact with the reactive distillable ionic liquid DIMCARB",
        "abstract": "The voltammetry of the polyoxometalate salts [Bu 4 N] 4 [SiW 12 O 40 ] (α, β, γ* isomers), [Bu 4 N] 4 [S 2 W 18 O 62 ] (α, γ* isomers) and [Bu 4 N] 4 [S 2 Mo 18 O 62 ] (α isomer) has been studied in the “distillable ionic liquid” DIMCARB (a mixture of adducts, both ionic and neutral, of dimethylamine and carbon dioxide). Dissolution of these salts tended to be slow and the anions, except [α-SiW 12 O 40 ] 4− , reacted with DIMCARB. However, high quality voltammograms were obtained from microparticles of the salts adhered to a glassy carbon electrode in contact with DIMCARB. Rapid dissolution of the reduced forms of each of the polyoxometalate anions provided reversible potential data. The higher basicity of the more highly reduced anions promoted interactions with the acidic solvent component of this medium. Comparison of reversible potentials indicated that the polarity of DIMCARB is similar to CH 3 CN, but smaller than that of conventional non-volatile ionic liquids and water.",
        "keywords": [
            "polyoxometalates",
            "distillable ionic liquid",
            "dimcarb",
            "voltammetry of adhered microparticles",
            "ionic liquid",
            "carbon dioxide"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Anand I. Bhatt",
                "org": "School of Chemistry, Monash University, Clayton, Melbourne, Vic. 3800, Australia"
            },
            {
                "name": "Alan M. Bond",
                "org": ""
            },
            {
                "name": "Anthony G. Wedd",
                "org": "Bio21 Molecular Science and Biotechnology Institute, 30 Flemington Road, Parkville, Vic. 3010, Australia"
            },
            {
                "name": "Janet L. Scott",
                "org": "ARC Special Research Centre for Green Chemistry, Monash University, Clayton, Vic. 3800, Australia"
            },
            {
                "name": "Christopher R. Strauss",
                "org": "ARC Special Research Centre for Green Chemistry, Monash University, Clayton, Vic. 3800, Australia"
            }
        ],
        "venue": "Electrochemistry Communications",
        "year": 2005
    },
    "kFEvSKaK": {
        "id": "kFEvSKaK",
        "title": "Changing the Look of Voltammetry",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Alan M. Bond",
                "org": ""
            },
            {
                "name": "Noel W. Duffy",
                "org": ""
            },
            {
                "name": "Si-Xuan Guo",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Darrell Elton",
                "org": ""
            }
        ],
        "venue": "Analytical Chemistry",
        "year": 2005
    },
    "rEQs0bfD": {
        "id": "rEQs0bfD",
        "title": "Voltammetric studies on the reduction of polyoxometalate anions in ionic liquids.",
        "abstract": "The electrochemical reduction of tetrabutylammonium salts of isostructural pairs of polyoxometalates [Bu4N]2[M6O19], [Bu4N]4[alpha-SiM12O40], and [Bu4N]4[alpha-S2M18O62] (M = Mo or W) has been investigated at glassy carbon electrodes in dissolved and surface-confined states in ionic liquids and other media. In the ionic liquid 1-n-butyl-3-methylimidazolium hexafluorophosphate [BMIM][PF(6)], between two and six reversible one-electron-transfer processes were detected. Detailed studies on the process [alpha-S2W18O62](4-/5-) in a range of ionic liquids, water, and conventional organic solvents (containing 0.1 M electrolyte) suggest that the polarity of the medium plays a key role in the determination of the reversible potential. Reduction processes involving very highly charged [alpha-S2W18O62](8-/9-/10-) species are strongly influenced by the purity of the medium.",
        "keywords": [
            "ionic liquid"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Alan M Bond",
                "org": ""
            },
            {
                "name": "Douglas R MacFarlane",
                "org": ""
            },
            {
                "name": "Stewart A Forsyth",
                "org": ""
            },
            {
                "name": "Jennifer M Pringle",
                "org": ""
            },
            {
                "name": "Andrew W A Mariotti",
                "org": ""
            },
            {
                "name": "Abigail F Glowinski",
                "org": ""
            },
            {
                "name": "Anthony G Wedd",
                "org": ""
            }
        ],
        "venue": "Inorganic chemistry",
        "year": 2005
    },
    "5W9L05yG": {
        "id": "5W9L05yG",
        "title": "Separation of electron-transfer and coupled chemical reaction components of biocatalytic processes using Fourier transform ac voltammetry.",
        "abstract": "The underlying electron-transfer and coupled chemical processes associated with biologically important catalytic reactions can be resolved using a combination of Fourier transform ac voltammetry with an analysis of the separated dc and ac components. This outcome can be achieved because the response associated with generation of the catalytic current is essentially confined to the steady-state dc component, whereas the electron-transfer step is dominant in the fundamental and higher harmonics. For the mediated oxidation of glucose with glucose oxidase, it was found that the underlying reversible redox chemistry of the mediator, ferrocenemonocarboxylic acid, as detected in the third and higher harmonics, was totally unaffected by introduction of the catalytic process. In contrast, for the catalytic reduction of molecular oxygen by cytochrome P450, slight changes in the P450 redox process were detected when the catalytic reaction was present. Simulations of a simple catalytic reaction scheme support the fidelity of this novel FT ac voltammetric approach for examining mechanistic nuances of catalytic forms of electrochemical reaction schemes.",
        "keywords": [
            "electron transfer",
            "fourier transform",
            "chemical reaction"
        ],
        "authors": [
            {
                "name": "Barry D. Fleming",
                "org": "School of Chemistry, Monash University, Clayton, Victoria 3800, Australia."
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Alan M. Bond",
                "org": ""
            },
            {
                "name": "Stephen G. Bell",
                "org": ""
            },
            {
                "name": "Luet-Lok Wong",
                "org": ""
            }
        ],
        "venue": "Analytical chemistry",
        "year": 2005
    },
    "wFd4eWpt": {
        "id": "wFd4eWpt",
        "title": "Voltammetric Studies on Decaphenylferrocene, Substituted Decaphenylferrocenes, and Their Oxidized Forms in Dichloromethane and Ionic Liquids",
        "abstract": "",
        "keywords": [
            "ionic liquid"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Alan M. Bond",
                "org": ""
            },
            {
                "name": "Herbert Schumann",
                "org": ""
            },
            {
                "name": "Klaudia Sühring",
                "org": ""
            }
        ],
        "venue": "Organometallics",
        "year": 2005
    },
    "uinuCz2D": {
        "id": "uinuCz2D",
        "title": "Mechanistic analysis of the electrocatalytic properties of dissolved alpha and beta isomers of [SiW12O40]4- and solid [Ru(bipy)3]2[alpha-SiW12O40] on the reduction of nitrite in acidic aqueous media.",
        "abstract": "Voltammetric studies on the reduction of alpha and beta isomers of the Keggin polyoxometalate anion [SiW12O40]4- reveal a series of electrochemically reversible processes in acidic aqueous media. In the presence of NO2-, catalytic current is detected in the potential region of the [SiW12O40]4-/5- process. Electronic spectroscopy and simulation of voltammetric data undertaken at variable [NO2-] and [H+] allow the following mechanism to be postulated, [SiW12O40]4- + e- <-->[SiW12O40]5-, H+ + HNO2 <--> NO+ + H2O, NO+ + [SiW12O40]5- --> NO + [SiW12O40]4-. The second-order rate constant for the rate-determining step is faster for the alpha isomer than for the beta one. This may be attributed to the different reversible potentials of -0.144 V (alpha isomer) and -0.036 V vs Ag/AgCl (beta isomer) and, hence, smaller driving force for an assumed outer sphere electron-transfer reaction in the case of beta isomer. A stable, water-insoluble, thin-film [Ru(bipy)3]2[alpha-SiW12O40] chemically modified electrode was generated electrochemically via ion-exchange of [Ru(bipy)3]2+ with Bu4N+ in the [Bu4N]4[alpha-SiW12O40] solid. The first reduction process with this modified electrode gives rise to the reaction [Ru(bipy)3]2[alpha-SiW12O40](solid) + H+(soln) + e- <--> H[Ru(bipy)3]2[alpha-SiW12O40](solid). The need to transfer a proton from the solution to the solid phase for charge neutralization purposes introduces a hydrogen-ion concentration dependence into this reaction, which is not found in the solution-phase study. Nevertheless, the voltammetric catalytic activity with respect to nitrite reduction is retained with the chemically modified electrode. However, nitrite catalysis with the [Ru(bipy)3]2[alpha-SiW12O40]-modified electrode is now independent of concentration of H+, rather than exhibiting a first-order dependence, and full mechanistic details for this process are unknown.",
        "keywords": [],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "School of Chemistry, Monash University, Clayton, Victoria 3800, Australia."
            },
            {
                "name": "Joo-Kheng Goh",
                "org": ""
            },
            {
                "name": "Wee-Tee Tan",
                "org": ""
            },
            {
                "name": "Alan M Bond",
                "org": ""
            }
        ],
        "venue": "Inorganic chemistry",
        "year": 2006
    },
    "DIJHy3YQ": {
        "id": "DIJHy3YQ",
        "title": "Application of power spectra patterns in Fourier transform square wave voltammetry to evaluate electrode kinetics of surface-confined proteins.",
        "abstract": "This paper describes an application of Fourier transform (FT) voltammetry that provides a quantitative evaluation of the electron-transfer kinetics of protein molecules attached to electrode surfaces. The potential waveform applied in these experiments consists of a large-amplitude square wave of frequency f superimposed onto the traditional triangular voltage used in dc cyclic voltammetry. The resultant current-time response, when Fourier transformed into the frequency domain, provides patterns of data at the even harmonic frequencies that arise from nonlinearity in the Faradaic response. These even harmonic contributions are ideally suited for kinetic evaluation of electron-transfer processes because they are highly selective to quasi-reversible behavior (insensitive to reversible or irreversible processes) and almost devoid of background charging current. Inverse FT methods can then be used to provide the wave shapes of the dc as well as the ac voltammetric components and other characteristics employed to detect the level of nonideality present relative to theoretical models based upon noninteracting surface-confined molecules. The new form of data evaluation has been applied to the electron-transfer properties of a typical biological electron carrier, the blue copper protein azurin, immobilized on polycrystalline gold electrodes modified with self-assembled monolayers of different length alkanethiols. Details of the electrode kinetics (rates of electron transfer, dispersion, and charge-transfer coefficients) as a function of alkanethiol, apparent surface coverage, and capacitance are all deduced from the square wave (FT-inverse FT) protocol, and the implications of these findings are considered.",
        "keywords": [
            "kinetics",
            "fourier transform"
        ],
        "authors": [
            {
                "name": "Barry D. Fleming",
                "org": "School of Chemistry, Monash University, Victoria 3800, Australia."
            },
            {
                "name": "Nicola L. Barlow",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Alan M. Bond",
                "org": ""
            },
            {
                "name": "Fraser A. Armstrong",
                "org": ""
            }
        ],
        "venue": "Analytical chemistry",
        "year": 2006
    },
    "PB5FpQw8": {
        "id": "PB5FpQw8",
        "title": "A critical assessment of electrochemistry in a distillable room temperature ionic liquid, DIMCARB",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Anand I. Bhatt",
                "org": ""
            },
            {
                "name": "Alan M. Bond",
                "org": ""
            },
            {
                "name": "Douglas R. MacFarlane",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Janet L. Scott",
                "org": ""
            },
            {
                "name": "Christopher R. Strauss",
                "org": ""
            },
            {
                "name": "Philip I. Iotov",
                "org": ""
            },
            {
                "name": "Sasha V. Kalcheva",
                "org": ""
            }
        ],
        "venue": "Green Chemistry",
        "year": 2006
    },
    "QFX07jkm": {
        "id": "QFX07jkm",
        "title": "Electrodeposition of lead on glassy carbon and mercury film electrodes from a distillable room temperature ionic liquid, DIMCARB",
        "abstract": "The electrochemical reduction of Pb2+ has been studied in the ‘distillable’ ionic liquid DIMCARB (a mixture of adducts of dimethylamine and carbon dioxide, comprising\n both neutral and ionic moieties). Voltammetric results show that Pb2+ is reduced in a single step to form Pb metal via a nucleation and growth mechanism on a glassy carbon electrode. Ex situ\n powder X-ray diffraction studies on deposited lead show the presence of both α- and β-PbO2, as well as elemental lead, suggesting the finely deposited lead particles are in an active rather than passive state. Chronamperometric\n and scanning electron microscope measurements show that the nucleation and growth follows a progressive nucleation mechanism\n on glassy carbon. Large peak–peak separations for the Pb reduction and oxidation are consistent with this mechanism and do\n not suggest electrochemical reversibility. However, experiments with co-deposition of Hg show that this irreversibility is\n a result of deposition onto a solid glassy carbon surface rather than a solvent effect. The diffusion coefficient of Pb2+ in DIMCARB has been calculated to be 1.8±0.4×10−7 cm2 s−1.",
        "keywords": [
            "Lead",
            "DIMCARB",
            "Voltammetry",
            "Dialcarbs",
            "Distillable room temperature ionic liquids",
            "Glassy carbon",
            "Nucleation and growth"
        ],
        "authors": [
            {
                "name": "Anand I. Bhatt",
                "org": "Monash University School of Chemistry Clayton Victoria 3800 Australia"
            },
            {
                "name": "Alan M. Bond",
                "org": "Monash University School of Chemistry Clayton Victoria 3800 Australia"
            },
            {
                "name": "Jie Zhang",
                "org": "Monash University School of Chemistry Clayton Victoria 3800 Australia"
            }
        ],
        "venue": "Journal of Solid State Electrochemistry",
        "year": 2007
    },
    "U3KaXSf4": {
        "id": "U3KaXSf4",
        "title": "Discrimination and evaluation of the effects of uncompensated resistance and slow electrode kinetics from the higher harmonic components of a fourier transformed large-amplitude alternating current voltammogram.",
        "abstract": "The influence of uncompensated resistance (also called the IRu effect, where I is current and Ru is uncompensated resistance) and slow electrode kinetics have been assessed for the dc and first five ac harmonics derived from Fourier transformed large-amplitude ac voltammetry. Resistance and rate constant conditions emphasized correspond to those where separation of effects attributable to either parameter is essentially impossible under conditions of dc cyclic voltammetry. Results derived from simulations and experiments demonstrate that it is relatively easy to discriminate and quantify contributions from these two effects over a wide range of values using the fourth and fifth harmonic ac components derived from single large-amplitude ac voltammetric measurement. Furthermore, these ac components also are essentially devoid of background charging current. Concepts developed initially from simulations are confirmed by experimental studies on the following: (a) the oxidation of ferrocene, in moderately resistive CH3CN and highly resistive CH2Cl2 (represents examples of IRu effect on a reversible electron-transfer process); (b) the reduction of a low 0.2 mM concentration of [Fe(CN)6]3- in the highly conductive 3 M KCl electrolyte media (case of slow kinetics with negligible IRu effect); (c) and reduction of a high 10 mM concentration of [Fe(CN)6]3- in less conductive aqueous 0.5 M KCl electrolyte media (example where the simultaneous effects of both IRu and slow kinetics need to be resolved).",
        "keywords": [
            "kinetics",
            "electron transfer",
            "oxydation",
            "simulation",
            "oxidation",
            "fourier transform",
            "rate constant"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Si-Xuan Guo",
                "org": ""
            },
            {
                "name": "Alan M Bond",
                "org": ""
            }
        ],
        "venue": "Analytical chemistry",
        "year": 2007
    },
    "kGbPLROv": {
        "id": "kGbPLROv",
        "title": "Detailed analysis of the electron-transfer properties of azurin adsorbed on graphite electrodes using DC and large-amplitude Fourier transformed AC voltammetry.",
        "abstract": "The analysis of dc cyclic voltammograms of surface-confined metalloproteins is complicated by large background currents, significant ohmic iRu drop, and frequency dispersion related to protein and electrode surface inhomogeneity. The use of large-amplitude Fourier transform ac voltammetry for the quantification of the electron-transfer properties of a thin film of redox-active protein azurin adsorbed onto edge-plane, basal-plane, and highly oriented pyrolytic graphite electrode surfaces has been evaluated and compared to results obtained by dc cyclic voltammetry. In principle, it has been established that fourth and higher harmonic sine-wave data are ideally suited for analysis of electron-transfer processes as they are almost completely devoid of background capacitance current contributions. However, uncompensated resistance has a higher impact on these components, as is the case with fast scan rate dc techniques, so strategies to include this term in the simulations have been investigated. Application of recommended strategies for the evaluation of the electron-transfer properties of azurin adsorbed onto three forms of graphite, each having different background or uncompensated resistance values, is described and compared to results obtained by traditionally used forms of cyclic voltammetry. The electron-transfer rate constant, k0', of azurin at a highly oriented pyrolytic graphite electrode surface was approximately 250 s(-1), compared with > or =1000 s(-1) at edge-plane and basal-plane graphite electrodes. The significantly lower k0' value found at the highly oriented pyrolytic graphite electrode was related to the relatively low level of edge-plane defect sites present at the surface of this electrode. However, analysis of high ac harmonics suggests that frequency dispersion is substantial at all electrode surfaces. Such effects in these diffusionless situations are significantly enhanced relative to solution-phase voltammetry, where overlay of diffusion layers minimizes the impact of heterogeneity.",
        "keywords": [
            "electron transfer",
            "fourier transform"
        ],
        "authors": [
            {
                "name": "Barry D. Fleming",
                "org": "School of Chemistry, Monash University, Victoria, Australia."
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Darrell Elton",
                "org": ""
            },
            {
                "name": "Alan M. Bond",
                "org": ""
            }
        ],
        "venue": "Analytical chemistry",
        "year": 2007
    },
    "1H9a6L6v": {
        "id": "1H9a6L6v",
        "title": "VOLTAMMETRIC ION SENSOR",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "alan m bond",
                "org": ""
            },
            {
                "name": "alexander r harris",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2007
    },
    "oWCQ2AOF": {
        "id": "oWCQ2AOF",
        "title": "Investigation of mediated oxidation of ascorbic acid by ferrocenemethanol using large-amplitude Fourier transformed ac voltammetry under quasi-reversible electron-transfer conditions at an indium tin oxide electrode.",
        "abstract": "The ability of the technique of large-amplitude Fourier transformed (FT) ac voltammetry to facilitate the quantitative evaluation of electrode processes involving electron transfer and catalytically coupled chemical reactions has been evaluated. Predictions derived on the basis of detailed simulations imply that the rate of electron transfer is crucial, as confirmed by studies on the ferrocenemethanol (FcMeOH)-mediated electrocatalytic oxidation of ascorbic acid. Thus, at glassy carbon, gold, and boron-doped diamond electrodes, the introduction of the coupled electrocatalytic reaction, while producing significantly enhanced dc currents, does not affect the ac harmonics. This outcome is as expected if the FcMeOH (0/+) process remains fully reversible in the presence of ascorbic acid. In contrast, the ac harmonic components available from FT-ac voltammetry are predicted to be highly sensitive to the homogeneous kinetics when an electrocatalytic reaction is coupled to a quasi-reversible electron-transfer process. The required quasi-reversible scenario is available at an indium tin oxide electrode. Consequently, reversible potential, heterogeneous charge-transfer rate constant, and charge-transfer coefficient values of 0.19 V vs Ag/AgCl, 0.006 cm s (-1) and 0.55, respectively, along with a second-order homogeneous chemical rate constant of 2500 M (-1) s (-1) for the rate-determining step in the catalytic reaction were determined by comparison of simulated responses and experimental voltammograms derived from the dc and first to fourth ac harmonic components generated at an indium tin oxide electrode. The theoretical concepts derived for large-amplitude FT ac voltammetry are believed to be applicable to a wide range of important solution-based mediated electrocatalytic reactions.",
        "keywords": [
            "electron transfer",
            "fourier transform",
            "indium tin oxide"
        ],
        "authors": [
            {
                "name": "Benchaporn Lertanantawong",
                "org": ""
            },
            {
                "name": "Anthony P O'Mullane",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Werasak Surareungchai",
                "org": ""
            },
            {
                "name": "Mithran Somasundrum",
                "org": ""
            },
            {
                "name": "Alan M Bond",
                "org": ""
            }
        ],
        "venue": "Analytical chemistry",
        "year": 2008
    },
    "ZoVQK01H": {
        "id": "ZoVQK01H",
        "title": "Efficient strategy for quality control of screen-printed carbon ink disposable sensor electrodes based on simultaneous evaluation of resistance, capacitance and Faradaic current by Fourier transform AC voltammetry",
        "abstract": "Two types of mass-produced, screen-printed carbon ink-based macrodisc electrodes suitable for routine sensing applications\n have been fabricated. Microscopic examination of these carbon ink electrode surfaces reveals that their surfaces are both\n rough and highly heterogeneous, consisting of random arrays of carbon particles of different sizes, as well as binder. Consequently,\n they may suffer from a lack of reproducibility in their performance because of variable resistance, capacitance or electroactive\n area. Use of a Fourier transform AC voltammetric protocol involving application of periodic waveform obtained from summation\n of five sine waves of variable frequency enabled resistance and capacitance, as well as DC and AC Faradaic currents associated\n with the model processes $${\\text{FcMeOH}} \\rightleftarrows {\\text{FcMeOH}}^{\\text{ + }} + {\\text{e}}^ - $$ or $$\\left[ {Ru\\left( {NH_3 } \\right)_6 } \\right]^{3 + } + e^ - \\rightleftarrows \\left[ {Ru\\left( {NH_3 } \\right)_6 } \\right]^{2 + } $$ (where FcMeOH is ferrocene methanol) to be assessed from a single experiment. Such data, which may be obtained rapidly via\n this approach, are highly suitable for quality control assessment.",
        "keywords": [
            "Thick-film carbon ink electrodes",
            "Fourier transform AC voltammetry",
            "Resistance",
            "Capacitance",
            "Quality control of electrode fabrication"
        ],
        "authors": [
            {
                "name": "Alexander R. Harris",
                "org": "Monash University School of Chemistry, ARC Center for Green Chemistry Clayton Victoria 3800 Australia"
            },
            {
                "name": "Jie Zhang",
                "org": "Monash University School of Chemistry, ARC Center for Green Chemistry Clayton Victoria 3800 Australia"
            },
            {
                "name": "Anastassija Konash",
                "org": "Monash University School of Chemistry, ARC Center for Green Chemistry Clayton Victoria 3800 Australia"
            },
            {
                "name": "Darrell Elton",
                "org": "Latrobe University Department of Electronic Engineering Bundoora Victoria 3086 Australia"
            },
            {
                "name": "Mark Hyland",
                "org": "Oxford Biosensors Limited Oxford Industrial Park, Mead Road Yarnton Oxfordshire OX5 1QU UK"
            },
            {
                "name": "Alan M. Bond",
                "org": "Monash University School of Chemistry, ARC Center for Green Chemistry Clayton Victoria 3800 Australia"
            }
        ],
        "venue": "Journal of Solid State Electrochemistry",
        "year": 2008
    },
    "oWDURnkZ": {
        "id": "oWDURnkZ",
        "title": "Prospects for a widely applicable reference potential scale in ionic liquids based on ideal reversible reduction of the cobaltocenium cation",
        "abstract": "Oxidation of ferrocene, Fe(cp) 2 or reduction of the cobaltocenium cation, [Co(cp) 2 ] + represent reversible processes that are widely used to provide a voltammetric potential reference scale. However, the [Fe(cp) 2 ] 0/+ process has been reported to exhibit complexities which may restrict its usefulness for this purpose in ionic liquids. In this study, the reduction of [Co(cp) 2 ] + in the ionic liquids, [bmpyr][Ntf 2 ], [emim][Ntf 2 ], and [bmim][PF 6 ] (bmpyr = 1-butyl-1-methylpyrrolidinium, emim = 1-ethyl-3-methylimidazolium, bmim = 1-butyl-3-methylimidazolium, Ntf 2 = bis(trifluoromethanesulfonyl)amide) is reported at macro, micro, and rotating disk electrodes. Reversible behaviour, after allowance for ohmic drop, and linear current–concentration relationships are attained over wide concentration ranges for all electrode configurations. Results support the use of the [Co(cp) 2 ] +/0 process for reference potential purposes, with non-idealities of the kind reported for ferrocene not being detected. Keywords Cobaltocenium reduction Reference potential scale Ionic liquids 1 Introduction Room temperature ionic liquids (RTILs) offer attractive advantages [1,2] in chemical synthesis [3] , liquid crystals [4] , separation science [5] , and electrochemistry [6] . In the latter case, RTILs may offer wide potential windows, good electrical conductivity and ion transport properties [7] . However, as the range of RTILs expands, attention must be paid to ensuring that electrode potential data can be compared accurately with values obtained in conventional solvent–electrolyte media. Even though Snook et al. [8] and Katayama [9] have shown that a reliable Ag|Ag + (RTIL) reference system is available, most electrochemical studies in RTILs have utilised platinum [10] or silver wire [11] quasi-reference electrodes, which are seldom reliable because their potential is sensitive to impurities, the type of electroactive species present, and other factors [12] . In organic solvent media it is now routine to employ voltammetric data from compounds such as ferrocene, Fe(cp) 2 and cobaltocenium salts, [Co(cp) 2 ] + X − , that exhibit a well-defined, highly reversible redox process, as an ‘internal potential standard’ [13–15] . Whilst the [Fe(cp) 2 ] 0/+ couple would seem ideal for this purpose in ionic liquids, reports by Nagy et al. [16] , Eisele et al. [17] , and Brooks et al. [18] have shown unexpected complexities in [bmim][PF 6 ], [bmim][BF 4 ], and [bmim][Ntf 2 ]. While the oxidation current for ferrocene is normally (and reliably) a linear function of concentration in organic electrolyte media, appreciable deviations from linearity have been reported in these studies, which implies that the diffusion coefficient of ferrocene is a function of concentration. In addition, ferrocene is often poorly soluble in ionic liquids [19] , and is moderately volatile, which is a problem when elevated temperatures or sub-atmospheric pressures are required. By contrast, cobaltocenium compounds are non-volatile and generally soluble in ionic liquids, where the reduction of the cobaltocenium cation appears to be an ideal reversible process [19] . However, no systematic study on the concentration range over which the [Co(cp) 2 ] + reduction process remains ideal is available. In light of the recent results obtained for ferrocene, this is an important issue that must be resolved. Herein we report [Co(cp) 2 ] + electrochemical data obtained with macro, micro, and rotating disk electrodes in widely used ionic liquids, and discuss the extent to which the reduction process displays Nernstian responses, and exhibits linear current versus concentration relationships. 2 Experimental Unless otherwise stated, solution preparations and electrochemical measurements were performed in an argon-purged dry box. 1-butyl-1-methylpyrrolidinium bis(trifluoromethanesulfonyl)amide, [bmpyr][Ntf 2 ] was purchased from Merck (<10 ppm water, <100 ppm chloride). 1-ethyl-3-methylimidazolium bis(trifluoromethanesulfonyl)amide [emim][Ntf 2 ] was synthesised according to a literature method [20] . 1-butyl-3-methylimidazolium hexafluorophosphate [bmim][PF 6 ] was obtained from Aldrich. [emim][Ntf 2 ] and [bmim][PF 6 ] were dried over basic alumina. Voltammetric measurements on [emim][Ntf 2 ] and [bmim][PF 6 ] showed that the halide content was below the limit of detection (⩽10 −5 M). Bis(cyclopentadienyl)cobalt(III) hexafluorophosphate, known as cobaltocenium hexafluorophosphate, [Co(cp) 2 ][PF 6 ], was obtained from Aldrich (98% purity), dried under vacuum for 24 h at elevated temperature, and stored in the glove-box. Preparation of ⩾50 mM [Co(cp) 2 ][PF 6 ] in [bmpyr][Ntf 2 ] required overnight stirring for complete dissolution. Total gravimetric and volumetric errors were less than 5%. Cyclic voltammetric studies (Ecochemie μAutolabIII potentiostat), employed 3 mm diameter glassy carbon (GC) and 1.6 mm diameter gold and platinum macrodisk working electrodes. An EG&G Princeton Applied Research Model 363 Potentiostat and a Metrohm 628-10 Rotating Disk Electrode (RDE) assembly were utilised for rotating disk measurements with a 2.9 mm diameter glassy carbon working electrode. Voltammetry with 11 μm diameter carbon fibre and 2 μm diameter platinum electrodes used a BAS Model 100B electrochemical workstation. The reference electrode was either Ag|Ag + (10 mM Agtf (tf = triflate) in [bmpyr][Ntf 2 ]) [8] , or a Ag wire quasi-reference electrode, while platinum wire served as the auxiliary electrode. Recently, Rogers et al. [13] have reported that the Ag|Ag + charge-transfer rate in ionic liquids is relatively slow. However, this couple can still provide a suitable reference electrode if the area of the electrode is large and potentiostatic control is used, as in this study. The RDE and microelectrode measurements were undertaken outside the glovebox under dry N 2 . All measurements were carried out at 23 ± 1 °C. BAS DigiSim ® version 3.0 software was used to simulate the [Co(cp) 2 ] +/0 reduction process. Viscosity was measured with an Anton Paar Automated Micro Viscometer. The 1 H and 13 C NMR experiments were performed at 20 °C (magnetic field strength of 7.04 T) with a Varian Unity-Plus 300 NMR Spectrometer. Chemical shifts were referenced to tetramethyl silane (TMS) and spectral shimming was achieved via free induction decay. 3 Results and discussion 3.1 Cyclic voltammetry in [bmpyr][Ntf 2 ] Cyclic voltammetric data obtained at GC, Au, and Pt working electrodes for the reduction of [Co(cp) 2 ] + in [bmpyr][Ntf 2 ] are summarised in Table 1 . The magnitude of the ratio of reduction to oxidation peak currents, i p red / i p ox , is close to unity at all electrodes, concentrations, and scan rates examined, as expected for a chemically reversible process. Cyclic voltammograms obtained with 5, 10, 20, 50, and 100 mM [Co(cp) 2 ][PF 6 ] at a glassy carbon electrode are shown in Fig. 1 . In the higher concentration and faster scan rate regimes, peak-to-peak separations between oxidative ( E p ox ) and reductive ( E p red ) peak potentials, Δ E p, increase ( Table 1 ) as expected when uncompensated resistance ( R u ) is present. However, at low concentration and slow scan rates, where iR u is minimised, Δ E p approaches the value of 57 mV expected for a reversible one-electron transfer process at 23 °C. The midpoint potential, E mid , was calculated from the average of E p red and E p ox [ E mid = ( E p red + E p ox )/2] and returned a value of −(1.73 ± 0.01) V vs. Ag|Ag + ( Table 1 ). This value is essentially independent of electrode material, scan rate and concentration, so is described as the reversible half-wave potential, E h [21] , which is related to the formal potential ( E °′ ) as in Eq. (1) . (1) E ∘ ′ = E h + RT nF ln D ox D red 1 / 2 Consequently, E h is only strictly equal to E°′ if the diffusion coefficients, D ox and D red, are identical. Studies in ionic liquids have indicated that diffusion coefficients for charged and uncharged species may differ significantly [22,23] . In the present case, if D ox and D red differ by a factor of two, then the difference between E h and E°′ would be less than 10 mV. Whilst such a difference cannot be ignored, it does not preclude use of the [Co(cp) 2 ] +/0 process as a suitable potential reference couple in ionic liquids. If it is assumed that mass transport occurs by linear diffusion, then the reduction peak current, i p red (A), should be linearly proportional to both the square root of scan rate and concentration, in accordance with the Randles-Sevcik relationship (2) i p red = 0.4463 nF nF RT 1 2 AD 1 2 v 1 2 c where n (=1) is the number of electrons in the charge-transfer step, A is the electrode area (cm 2 ), D is the diffusion coefficient (cm 2 s −1 ), v is the scan rate (V s −1 ), and c is the concentration (mol cm −3 ). In the case of reduction of [Co(cp) 2 ] + in [bmpyr][Ntf 2 ], the voltammetric data conformed to the Randles-Sevcik equation over a wide range of conditions. Thus reduction peak currents are linearly proportional ( Fig. 2 ) to the square root of scan rate (5–100 mV s −1 ) and to concentration (5–100 mM). To quantify the effect of uncompensated resistance ( iR u ), voltammetric simulations for a reversible process were undertaken using experimentally known parameters with R u set to zero and D red and D ox = 1.2 × 10 −7 cm 2 s −1 ( Figs. 1 and 2 ). Only at current densities above about 1.2 mA cm −2 are there significant differences between predicted and experimental peak currents. The value of R u required for matching of simulated and experimental data was (700 ± 150) Ω. The data ( Fig. 2 ) are therefore consistent with a concentration-independent diffusion coefficient of (1.2 ± 0.1) × 10 −7 cm 2 s −1 for [Co(cp) 2 ] + in [bmpyr][Ntf 2 ]. Importantly, none of the complexity reported for the oxidation of ferrocene in ionic liquids has been detected for the [Co(cp) 2 ] +/0 process in [bmpyr][Ntf 2 ]. 3.2 Steady state reduction of [Co(cp) 2 ] + Cyclic voltammetric data in [bmpyr][Ntf 2 ] obey conventional mass transport theory, but exhibit iR u distortion at high concentrations. In contrast, steady state limiting current data obtained from rotating disk electrode (RDE) and microdisc electrode voltammetry should be devoid of iR u drop, thereby allowing conformance to the relevant mass transport theory to be analysed in a straightforward manner. A RDE voltammogram for the reduction of [Co(cp) 2 ] + in [bmpyr][Ntf 2 ] is presented in Fig. 3 (inset). Limiting current data ( i ss ) measured at the point where the response first attains steady state conform closely ( Fig. 3 ) to the Levich equation, (3) i ss = 0.62 n F A c D 2 3 υ - 1 6 ω 1 2 using kinematic viscosity ( υ ) = 60 cm 2 s −1 , and with ω = rotation rate (rad s −1 ). The diffusion coefficient at 1500 rpm from Eq. (3) was (1.29 ± 0.08) × 10 -7 cm 2 s −1 . The value was independent of concentration over the range of 10–100 mM and is in excellent agreement with that deduced from cyclic voltammetry [(1.2 ± 0.1) × 10 −7 cm 2 s −1 ]. Steady state limiting currents could also be obtained for reduction of [Co(cp) 2 ] + in [emim][Ntf 2 ] at a 11 μm diameter carbon fibre electrode, provided a slow scan rate of 1 mV s −1 was used ( Fig. 4 , inset). The diffusion-controlled i ss values measured under these conditions, at −1.6 V (vs. Ag wire) exhibited a linear relationship with [Co(cp) 2 ] + concentration over the range of 2–300 mM, which suggests that contributions from either electron hopping or migration are not significant under these experimental conditions (both terms should enhance the current as a function of concentration). Application of Eq. (4) , (4) I ss = 4 n F D r c where r is the radius of the electrode, yields a diffusion coefficient of (3.27 ± 0.02) × 10 -7 cm 2 s −1 . To investigate whether migration or electron hopping (self-exchange) might contribute in other ionic liquids, the dependence of i ss on the [Co(cp) 2 ] + concentration also was investigated in the much more viscous [bmim][PF 6 ]. A smaller, 2 μm diameter Pt microdisc electrode was required with this ionic liquid to achieve a near steady state response. Values of i ss , measured at −1.45 V (vs. Ag wire) were linearly dependent on [Co(cp) 2 ] + concentration over the range of 5–100 mM, which supports the conclusions reached for [emim][Ntf 2 ]. Application of Eq. (4) led to a diffusion coefficient of (3.73 ± 0.04) × 10 -8 cm 2 s −1 . In summary, the diffusion coefficient for [Co(cp) 2 ] + is: (i) (3.27 ± 0.02) × 10 −7 cm 2 s −1 in [emim][Ntf 2 ]; (ii) (1.29 ± 0.08) × 10 −7 cm 2 s −1 in [bmpyr][Ntf 2 ]; (iii) (3.73 ± 0.04) × 10 −8 cm 2 s −1 in [bmim][PF 6 ]. This decreasing trend mirrors an increasing trend in ionic liquid viscosity (34 cP [24] , 85 cP [8] , and 207 cP [24] for [emim][Ntf 2 ], [bmpyr][Ntf 2 ], and [bmim][PF 6 ] at 25 °C, respectively). Further, a detailed electrochemical study of [Co(cp) 2 ] + in the distillable ionic liquid, DIMCARB, over a concentration range of 5–250 mM, yielded a diffusion coefficient of 1.2 × 10 −7 cm 2 s −1 at a viscosity of 93.4 cP [25] . Clearly, the [Co(cp) 2 ] +/0 process displays near-ideal mass transport controlled behaviour in ionic liquids over a substantial range of viscosities and ionic compositions. The close-to-ideal voltammetry in several ionic liquids, over a reasonably wide concentration range, implies that the addition of [Co(cp) 2 ][PF 6 ] does not significantly alter key properties. Thus the viscosity of [emim][Ntf 2 ] was found to increase by only 1% on addition of 5 mM [Co(cp) 2 ][PF 6 ]. Furthermore, NMR chemical shift data are essentially independent of concentration. Thus, 13 C resonances for the ten equivalent cyclopentadienyl carbon nuclei and 1 H (cyclopentadienyl) NMR data all lie in the range (87.35 ± 0.65) and (5.62 ± 0.01) ppm, respectively for [Co(cp) 2 ][PF 6 ] concentrations of 5, 10, 20, 50 and 100 mM in [bmpyr][Ntf 2 ]. The lack of appreciable variation in chemical shift for [Co(cp) 2 ] + nuclei supports the contention that the speciation of this cation does not change significantly over the concentration range of interest. 4 Conclusions The voltammetry of the cobaltocenium cation, when present as the hexafluorophosphate salt, has been found to provide a near-ideal system for reference potential calibration purposes in a range of ionic liquids. Thus, the [Co(cp) 2 ] +/0 process in [bmpyr][Ntf 2 ] is close to Nernstian at carbon, gold, and platinum electrodes. Importantly, the midpoint potential obtained from cyclic voltammetry is independent of electrode material, scan rate and concentration over wide ranges and linear peak (cyclic voltammetry) or steady state current (RDE or microelectrode voltammetry) dependencies on concentration are observed, as required for a mass transport controlled process. Two caveats noted are: (i) distortion of the voltammograms due to iR u drop may need to be considered in ionic liquids, particularly at higher [Co(cp) 2 ] + concentrations or scan rates; (ii) emerging evidence of significant differences in the diffusion coefficients of charged and neutral halves of redox couples requires caution when comparing reversible potentials referenced to [Co(cp) 2 ] +/0 in different ionic liquids. Nevertheless, the behaviour of the [Co(cp) 2 ] +/0 system seems inherently simpler than that reported for the [Fe(cp) 2 ] 0/+ process and on this basis should provide a superior potential reference redox system. Acknowledgements We thank Drs. Snook and Best for assistance with reference electrode preparation, and Drs. Ruether and Crossley for synthesis of [emim][Ntf 2 ], and Dr. Huang for assistance with viscosity measurements. References [1] T. Welton Chem. Rev. 99 1999 2071 [2] S.A. Forsyth J.M. Pringle D.R. MacFarlane Aust. J. Chem. 57 2004 113 [3] R. Sheldon Chem. Commun. 2001 2399 [4] D.J. Abdallah A. Robertson H.F. Hsu R.G. Weiss J. Am. Chem. Soc. 122 2000 3053 [5] A.E. Visser R.P. Swatloski W.M. Reichert S.T. Griffin R.D. Rogers Ind. Eng. Chem. Res. 39 2000 3596 [6] P. Chen Y. Lin I. Sun J. Electrochem. Soc. 146 1999 3290 [7] P.C. Trulove R.A. Mantz P. Wasserscheid T. Welton Ionic Liquids in Synthesis 2002 Wiley-VCH Weinheim [8] G.A. Snook A.S. Best A.G. Pandolfo A.F. Hollenkamp Electrochem. Commun. 8 2006 1405 [9] Y. Katayama H.E. Ohno Electrochemical Aspects of Ionic Liquids 2005 John Wiley & Sons New Jersey 31 [10] P.A.Z. Suarez V.M. Selbach J.E.L. Dullius S. Einloft C.M.S. Piatnicki D.S. Azambuja R.F. de Souza J. Dupont Electrochim. Acta 42 1997 2533 [11] R.G. Evans O.V. Klymenko C. Hardacre K.R. Seddon R.G. Compton J. Electroanal. Chem. 556 2003 179 [12] A.M. Bond P.A. Lay J. Electroanal. Chem. 199 1986 285 [13] E.I. Rogers D.S. Silvester S.E. WardJones L. Aldous C. Hardacre A.J. Russell S.G. Davies R.G. Compton J. Phys. Chem. C 111 2007 13957 [14] R.S. Stojanovic A.M. Bond Anal. Chem. 65 1993 56 [15] G. Gritzner J. Kuta Pure Appl. Chem. 56 1984 461 [16] L. Nagy G. Gyetvai L. Kollár G. Nagy J. Biochem. Biophys. Methods 69 2006 121 [17] S. Eisele M. Schwarz B. Speiser C. Tittel Electrochim. Acta 51 2006 5304 [18] C.A. Brooks A.P. Doherty Electrochem. Commun. 6 2004 867 [19] V.M. Hultgren A.W.A. Mariotti A.M. Bond A.G. Wedd Anal. Chem. 74 2002 3151 [20] P. Bonhote A.P. Dias N. Papageorgiou K. Kalyanasundaram M. Gratzel Inorg. Chem. 35 1996 1168 [21] K.B. Oldham J.C. Myland Fundamentals of Electrochemical Science 1994 Academic Press San Diego [22] M.C. Lagunas W.R. Pitner J. van den Berg K.R. Seddon R.D. Rogers K.R. Seddon Ionic Liquid as Green Solvents: Progress and Prospects 2003 American Chemical Society Washington DC 421 [23] R.G. Evans O.V. Klymenko P.D. Price S.G. Davies C. Hardacre R.G. Compton ChemPhysChem 6 2005 526 [24] P.C. Trulove R.A. Mantz P. Wasserscheid T. Welton Ionic Liquids in Synthesis 2002 Wiley-VCH Weinheim 60 [25] A.I. Bhatt A.M. Bond D.R. MacFarlane J. Zhang J.L. Scott C.R. Strauss P.I. Iotov S.V. Kalcheva Green Chem. 8 2006 161",
        "keywords": [
            "ionic liquid",
            "ionic liquids"
        ],
        "authors": [
            {
                "name": "Stevanus K. Sukardi",
                "org": "CSIRO Energy Technology, Box 312, Clayton South, Vic 3169, Australia"
            },
            {
                "name": "Jie Zhang",
                "org": "Institute of Bioengineering and Nanotechnology, Singapore"
            },
            {
                "name": "Iko Burgar",
                "org": "CSIRO Materials and Manufacturing Technology, Private Bag 33, Clayton South, Vic 3169, Australia"
            },
            {
                "name": "Michael D. Horne",
                "org": "CSIRO Minerals, Box 312, Clayton South, Vic 3169, Australia"
            },
            {
                "name": "Anthony F. Hollenkamp",
                "org": ""
            },
            {
                "name": "Douglas R. MacFarlane",
                "org": "School of Chemistry, Monash University, Clayton, Vic 3800, Australia"
            },
            {
                "name": "Alan M. Bond",
                "org": ""
            }
        ],
        "venue": "Electrochemistry Communications",
        "year": 2008
    },
    "hWdbhNC9": {
        "id": "hWdbhNC9",
        "title": "Higher harmonic large-amplitude Fourier transformed alternating current voltammetry: analytical attributes derived from studies of the oxidation of ferrocenemethanol and uric acid at a glassy carbon electrode.",
        "abstract": "An analytical evaluation of the higher ac harmonic components derived from large amplitude Fourier transformed voltammetry is provided for the reversible oxidation of ferrocenemethanol (FcMeOH) and oxidation of uric acid by an EEC mechanism in a pH 7.4 phosphate buffer at a glassy carbon (GC) electrode. The small background current in the analytically optimal fifth harmonic is predominantly attributed to faradaic current associated with the presence of electroactive functional groups on the GC electrode surface, rather than to capacitive current which dominates the background in the dc, and the initial three ac harmonics. The detection limits for the dc and the first to fifth harmonic ac components are 1.9, 5.89, 2.1, 2.5, 0.8, and 0.5 microM for FcMeOH, respectively, using a sine wave modulation of 100 mV at 21.46 Hz and a dc sweep rate of 111.76 mV s (-1). Analytical performance then progressively deteriorates in the sixth and higher harmonics. For the determination of uric acid, the capacitive background current was enhanced and the reproducibility lowered by the presence of surface active uric acid, but the rapid overall 2e (-) rather than 1e (-) electron transfer process gives rise to a significantly enhanced fifth harmonic faradaic current which enabled a detection limit of 0.3 microM to be achieved which is similar to that reported using chemically modified electrodes. Resolution of overlapping voltammetric signals for a mixture of uric acid and dopamine is also achieved using higher fourth or fifth harmonic components, under very low background current conditions. The use of higher fourth and fifth harmonics exhibiting highly favorable faradaic to background (noise) current ratios should therefore be considered in analytical applications under circumstances where the electron transfer rate is fast.",
        "keywords": [
            "fourier transform",
            "limits of detection"
        ],
        "authors": [
            {
                "name": "Anthony P. O’Mullane",
                "org": "School of Chemistry, Monash University, Clayton, Victoria 3800, Australia."
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Anna Brajter-Toth",
                "org": ""
            },
            {
                "name": "Alan M. Bond",
                "org": ""
            }
        ],
        "venue": "Analytical chemistry",
        "year": 2008
    },
    "8xR47zIf": {
        "id": "8xR47zIf",
        "title": "Theoretical and experimental evaluation of screen-printed tubular carbon ink disposable sensor well electrodes by dc and Fourier transformed ac voltammetry",
        "abstract": "Mass-produced, screen-printed, carbon-ink-based microtubular band (well) electrodes, suitable for routine sensing applications,\n have been fabricated and evaluated with respect to their theoretical and analytical performance. Microscopic examination of\n the electrode surface reveals they are inherently rough and could easily suffer from high and variable resistance, capacitance\n and area, unless care is taken to minimise these problems. Simulation models have been applied to analyse cyclic voltammetric\n responses obtained at the well electrodes. Results of these theoretical calculations further demonstrate the care needed with\n electrode design and resistance in carbon ink electrodes. Substantial differences in voltammetry when wells are produced by\n mechanically punching or laser drilling are considered. The application of multi- and single-frequency Fourier Transform ac\n voltammetry, previously applied to planar carbon ink disc electrodes for quality control purposes, is now demonstrated with\n respect to the microtubular band electrode geometry. Theoretical and practical limitations are discussed, as is the analytical\n application to the reversible $$\\left[ {{\\text{Ru}}\\left( {{\\text{NH}}_3 } \\right)_6 } \\right]^{3 + } + e^ - \\rightleftharpoons \\left[ {{\\text{Ru}}\\left( {{\\text{NH}}_3 } \\right)_6 } \\right]^{2 + } $$ redox couple in the presence of oxygen in aqueous solution.",
        "keywords": [
            "Screen-printed tubular band electrodes",
            "Well electrodes",
            "Fourier Transform ac voltammetry",
            "Electrode performance"
        ],
        "authors": [
            {
                "name": "Anastassija Konash",
                "org": "Monash University School of Chemistry and ARC Centre for Green Chemistry Clayton Victoria 3800 Australia"
            },
            {
                "name": "Alexander R. Harris",
                "org": "Monash University School of Chemistry and ARC Centre for Green Chemistry Clayton Victoria 3800 Australia"
            },
            {
                "name": "Jie Zhang",
                "org": "Monash University School of Chemistry and ARC Centre for Green Chemistry Clayton Victoria 3800 Australia"
            },
            {
                "name": "Darrell Elton",
                "org": "Latrobe University Department of Electronic Engineering Bundoora Victoria 3086 Australia"
            },
            {
                "name": "Mark Hyland",
                "org": "Oxford Industrial Park Oxford Biosensors Ltd Mead Road Yarnton OX5 1QU Oxfordshire UK"
            },
            {
                "name": "Gareth Kennedy",
                "org": "Monash University School of Chemistry and ARC Centre for Green Chemistry Clayton Victoria 3800 Australia"
            },
            {
                "name": "Alan M. Bond",
                "org": "Monash University School of Chemistry and ARC Centre for Green Chemistry Clayton Victoria 3800 Australia"
            }
        ],
        "venue": "Journal of Solid State Electrochemistry",
        "year": 2009
    },
    "kiPoEAp8": {
        "id": "kiPoEAp8",
        "title": "A doubly amplified electrochemical immunoassay for carcinoembryonic antigen.",
        "abstract": "An ultrasensitive electrochemical immunoassay (EIA) for the detection of carcinoembryonic antigen (CEA) is described in this report. The assay involves utilizing enzyme-catalyzed deposition of a redox polymer and electrocatalytic oxidation of ascorbic acid (AA) by the deposited redox polymer, a dual-amplification scheme to enhance analytical signals. Briefly, CEA capturing antibody and redox polymer anchoring agent were covalently immobilized on a gold electrode. After incubating with CEA, the electrode was treated in detection antibody-glucose oxidase conjugate solution. Thereafter, it was dipped into the redox polymer solution. Upon the addition of glucose, the redox polymer was enzymatically reduced and deposited on the electrode surface. The deposited redox polymer exhibits excellent electrocatalytic activity towards the oxidation of AA. Consequently, CEA could be quantified amperometrically. This electrochemical immunoassay combines the specificity of the immunological reaction with the sensitivity of the doubly amplified electrochemical detection.",
        "keywords": [
            "glucose oxidase",
            "immunoassay",
            "redox polymer",
            "amperometry",
            "carcinoembryonic antigen",
            "analytic signal",
            "enzyme"
        ],
        "authors": [
            {
                "name": "Zhiqiang Gao",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": "Institute of Bioengineering and Nanotechnology, 31 Biopolis Way, 138669, Singapore"
            },
            {
                "name": "Boon Ping Ting",
                "org": "Institute of Bioengineering and Nanotechnology, 31 Biopolis Way, 138669, Singapore"
            }
        ],
        "venue": "Biosensors & bioelectronics",
        "year": 2009
    },
    "ip5PORth": {
        "id": "ip5PORth",
        "title": "The solid-state Ag/AgCl process as a highly sensitive detection mechanism for an electrochemical immunosensor.",
        "abstract": "The highly characteristic solid-state Ag/AgCl process was used as an ultrasensitive detection mechanism for electrochemical sensors, such as a prostate-specific antigen immunosensor.",
        "keywords": [],
        "authors": [
            {
                "name": "Boon Ping Ting",
                "org": "Institute of Bioengineering and Nanotechnology, 31 Biopolis Way, The Nanos, Singapore 138669, Singapore."
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Majad Khan",
                "org": ""
            },
            {
                "name": "Yi Yan Yang",
                "org": ""
            },
            {
                "name": "Jackie Y. Ying",
                "org": ""
            }
        ],
        "venue": "Chemical communications (Cambridge, England)",
        "year": 2009
    },
    "CjNCi3hV": {
        "id": "CjNCi3hV",
        "title": "A DNA biosensor based on the detection of doxorubicin-conjugated Ag nanoparticle labels using solid-state voltammetry",
        "abstract": "This report describes an electrochemical biosensor for the detection of short DNA oligonucleotide of the avian flu virus H5N1 with sequence 5′-CCA AGC AAC AGA CTC AAA-3′. To fabricate this DNA biosensor, a gold (Au) electrode surface was modified with thiolated DNA probes with a sequence complementary to the target DNA. This modified Au electrode was incubated in a buffer solution containing the target DNA to form double-stranded DNA (ds-DNA) through hybridization. The ds-DNA on the electrode surface was then labeled with silver nanoparticles conjugated with a well-known DNA intercalator, doxorubicin. By performing cyclic voltammetry in an aqueous KCl solution (0.3 M), the silver nanoparticle labels were detected as a result of the highly characteristic solid-state Ag/AgCl redox process. The signal obtained was subsequently used to quantify the amount of DNA. A detection limit of 1 pM has been achieved with this new DNA biosensor. Keywords Flu virus H5N1 DNA biosensor Electrochemistry Silver nanoparticle labels Solid-state voltammetry Doxorubicin",
        "keywords": [
            "silver nanoparticle",
            "electrochemistry",
            "detection limit"
        ],
        "authors": [
            {
                "name": "Boon Ping Ting",
                "org": "Institute of Bioengineering and Nanotechnology, 31 Biopolis Way, The Nanos, Singapore 138669, Singapore"
            },
            {
                "name": "Jie Zhang",
                "org": "Institute of Bioengineering and Nanotechnology, 31 Biopolis Way, The Nanos, Singapore 138669, Singapore"
            },
            {
                "name": "Zhiqiang Gao",
                "org": "Institute of Bioengineering and Nanotechnology, 31 Biopolis Way, The Nanos, Singapore 138669, Singapore"
            },
            {
                "name": "Jackie Y. Ying",
                "org": ""
            }
        ],
        "venue": "Biosensors and Bioelectronics",
        "year": 2009
    },
    "7SZP41nw": {
        "id": "7SZP41nw",
        "title": "Designer based Fourier transformed voltammetry: A multi-frequency, variable amplitude, sinusoidal waveform",
        "abstract": "Fourier transform methods allow custom-designed complex waveforms to be used in ac voltammetry. Commonly a single wave or sum of sine waves of variable angular frequency ( ω ) but constant amplitude ( Δ E ) superimposed onto a dc ramp are employed. In the present case, a custom-designed waveform consisting of a combination of eight sine waves is introduced, with the property that each sine wave within the composite waveform has the property Δ E i ∝ 1 / ω i where i represents the i th sine wave. Frequencies (and amplitudes) employed in a single experiment cover the range from 34.94 Hz (20 mV) to 1970.01 Hz (2.66 mV). Reversibility is readily detected via use of this designer waveform by noting a constant peak height ( I p ( ω t ) ) for all eight frequencies, whereas I p ( ω t ) values decrease in a characteristic manner with increasing frequency for a quasi-reversible process or when uncompensated resistance is present, as demonstrated experimentally and theoretically. Importantly, background charging current contributions do not increase to a level that makes measurement of faradaic current difficult at high frequencies and hence charging current is readily corrected for over the entire frequency range of interest. Keywords Designer ac waveform Fourier transform voltammetry Variable amplitude and frequency 1 Introduction During the last decade, quantitative use of the technique of Fourier transformed (FT) ac voltammetry has been expanded [1,2] to accommodate large levels of nonlinearity introduced by application of potential perturbations with amplitudes much larger than those customarily employed in ac voltammetry or impedance spectroscopy [3] . Typically, in these recent studies, a sinusoidal waveform of amplitude up to 200 mV with a frequency of 10 Hz–50 kHz is superimposed onto the triangular waveform used in dc cyclic voltammetry. The large amplitude method, when analysed in the frequency domain via a Fourier transform-inverse Fourier transform sequence, provides simultaneous access to the dc and fundamental harmonic ac responses, in addition to higher ac harmonics that emerge from the nonlinearity. This large-amplitude FT-ac technique is advantageous in studies of electrode kinetics because of the well-defined patterns of behaviour that emerge in the now readily detected higher harmonics [4] , with minimal problem from charging current. The large amplitude technique has been applied successfully to elucidate details of the electrochemistry of complex electrode processes such as surface-bound azurin [5] and mediated oxidation of acerbic acid by ferrocenemethanol [6] . Theoretical treatments for the sinusoidal version of the large-amplitude FT-ac method have been developed by Engblom et al. [1] and Gavaghan et al. [2,7–9] . Furthermore, recent work from several laboratories has demonstrated that instrumentation can be developed in which a periodic ac waveform of any amplitude may be superimposed onto a linear or triangular dc voltage [1,2,5,8,10] . Gavaghan et al. have also described a large-amplitude FT square-wave ac method that has been termed ‘square-wave voltammetry in the frequency domain’ [9] . Other waveforms have also been suggested that are based on the Fourier series of sawtooth or other waveforms. Custom-designed instrumentation has been developed to specifically accommodate the sinusoidal and the other variations of the FT-ac technique [11,12] . As part of our effort to further develop the FT-ac voltammetric technique, we now introduce a multi-frequency and variable amplitude waveform. The concept behind this initial development of a designer waveform for characterising a particular class of electrochemical processes is to identify combinations of sine waves that allow the rapid identification of the nature of charge transfer processes described by Eq. (1) where E o ′ is the reversible formal potential, k o ′ is the heterogeneous charge transfer rate constant at E o ′ , n is the number of electrons transferred and α is the charge transfer coefficient. (1) A + ne - ⇌ α , k o ′ , E o ′ B . The waveform introduced for identifying reversibility in this paper is a combination of sine waves, with the property that each sine wave within the composite waveform has the property Δ E i ∝ 1 / ω i , where ω i and Δ E i are the angular frequency and the amplitude of the i th sine wave, respectively. The concept is based on the analytical solution available in small amplitude ac voltammetry when a single sine wave is applied, under conditions of planar diffusion, (2) I ( ω t ) = n 2 F 2 Ac A ( ω D A ) 1 2 Δ E 4 RT cosh 2 j 2 sin ω t + π 4 , where A is the electrode area, c A is the concentration of species A , n is the number of electrons transferred ( n = 1 in the present case), D A is the diffusion coefficient of species A , t is time, j = nF ( E dc - E o ′ ) / RT and E dc is the dc component of the applied potential, E dc = E initial + vt , where E initial is the starting potential and v is the scan rate. Thus, under conditions where this relationship holds, and a waveform where Δ E i ∝ 1 / ω i is applied in a single experiment the fundamental harmonic peak current is such that I p ( ω t ) ∝ ω 1 2 Δ E . Reversibility, achieved when k o ′ is very large, is rapidly recognised when using the custom-designed waveform by detection of a fundamental harmonic peak height ( I p ( ω t ) ) that is independent of frequency. In the case of quasi-reversibility, a characteristic frequency dependence is also detected in which I p ( ω t ) decreases with increasing frequency, as also occurs if uncompensated resistance is significant. Finally, it is noted that traditionally when waveforms with constant Δ E values are used, the background current, which is proportional to ω , becomes very large at high frequencies, making the faradaic current hard to detect. In the present case, the background current does not increase very dramatically with frequency and hence correction, even at high frequencies, is facilitated. 2 Experimental 2.1 Instrumentation Details of the FT-ac voltammetric instrumentation are provided in [13] . Initial estimates of the uncompensated resistance ( R u ) values were obtained using a BAS (Bioanalytical Systems)-Epsilon potentiostat and applying a small potential step in a potential region where no faradaic current flows. Analysis of the charging current versus time curve allows R u to be extracted, as described in Ref. [6] . 2.1.1 Chemicals and reagents All chemicals and the solvent dichloromethane were of reagent grade purity and used as received from the manufacturer (Aldrich). The deionized water was obtained from a MilliQ–MilliRho purification system. 2.1.2 Instrumentation and procedures A conventional single compartment, three-electrode cell was employed in all voltammetric measurements, with glassy-carbon (GC, 7.07 mm 2 ), platinum (Pt, 3.14 mm 2 ) or gold (Au, 3.14 mm 2 ) macrodisk working electrodes, an Ag∣AgCl (0.5 M KCl) reference electrode and a platinum wire auxiliary electrode. The disc-shaped working electrodes were constructed by sealing glassy-carbon or metal rods into insulating Kel-F sheaths with epoxy resin. Before use, the surfaces of these electrodes were manually polished with an aqueous slurry of 0.1 or 0.05 μ m alumina particles (Bioanalytical Systems) on a microcloth polishing cloth (Buehler, Lake Bluff, IL) and then rinsed thoroughly with water. In initial experiments, GC, Au or Pt electrodes were immersed in 10 ml of aqueous solutions containing 0.100 mM; 0.202 mM; 0.300 mM; 0.404 mM; 1.00 mM or 2.00 mM Ferrocenemethanol (FcMeOH) with 0.50 M KCl as the supporting electrolyte. The oxidation of FcMeOH was used as an example of a reversible process. Other systems studied were: reduction of [ Ru ( NH 3 ) 6 ] 3 + (reversible) and [ Fe ( CN ) 6 ] 3 - (quasi-reversible), again in 0.50 M KCl aqueous electrolyte; and oxidation of FcMeOH (reversible) in dichloromethane (0.1 M Bu 4 NPF 6 ). The latter was used to assess the impact of a high level of uncompensated resistance. Solutions were purged with nitrogen for at least 5 min prior to commencement of a voltammetric experiment. All experiments were carried out at ( 20 ± 1 ) ° C . The waveform used in the FT-ac voltammetric experiments was a composite, eight component sine-wave signal superimposed onto the dc potential to give a total potential E t where (3) E t = E dc + ∑ i = 1 8 Δ E i sin ( ω i t ) , with the frequencies, ω i , and amplitudes, Δ E i , as given in Table 1 . The individual sine waves were not phase randomised, as is sometimes the case in experiments where all amplitudes are the same [11] . However, consideration was given to minimisation of overlap of higher harmonic terms on the basis of an algorithm available in the literature [11] . Instrumental and FT requirements mean that 2 n data points need to be obtained. The chosen scan rate and potential range specified in Table 1 meant that the combination given there was identified as being suitable for implementation of the designer waveform with minimal overlap from higher harmonic and frequency sum and difference terms. In particular, these nonlinear terms were not within 5–10 Hz of the eight applied frequencies. The amplitudes were chosen to be in the range of 20–2 mV and the frequencies ranging from 34.94 to 1970.01 Hz are geometrically spaced over a range that allows a substantial faradaic component to be measured relative to background current, under all conditions. However, it may be noted that the number of sine waves chosen in the designer waveform need not be eight, nor have the specific frequencies selected for the present study. 2.1.3 Data analysis and simulations The experimental data, obtained with the FT-ac instrumentation, yield current, time, and applied dc potential as the output information. The data are plotted as current versus time and then transformed into frequency-related power spectra for further analysis. The raw FT-ac data obtained from experiments contains a very large number of data points ( 2 18 ). Consequently, processing the full set of data is slow. For this reason, a ‘decimation’ data reduction process is implemented in the frequency domain, where the first 2 15 data points present in the raw data are retained and all the higher frequency data is discarded before the inverse Fourier transform operation is applied. This strategy removes data that contains no information relevant to the electrochemical reaction (>2000 Hz) being studied, and significantly reduces the data file size needed for the iFT operation while maintaining all useful information. Another problem with raw ac data is the presence of background (charging) current. It is well known that in the fundamental harmonic response, the background current may dominate the voltammetry, particularly at high frequency, so that quantitative analysis of the faradaic component associated with electron transfer may require employment of a background correction procedure. Measurement of the background current at selected potential ranges on both sides of the region where Faradaic current is detected, interpolation to give values in this potential region using a polynomial fit and vectorial subtraction of the calculated background were used in the present case. The background current does not contribute significantly to the second and higher harmonic ac voltammograms. Consequently, background correction is unnecessary for measurement of these higher order components. Analysis of the kinetics was based on peak height versus frequency profiles. However, full simulations were carried out using the procedure described below. Fitting of experimental data with simulated results for the quasi-reversible process was undertaken in an essentially heuristic manner: Step 1. Identify the reversibility or otherwise of an electrode process by examining the lowest concentration data set, where the IR u influence should be minimal, and compare it against predictions based on the reversible case (i.e. I p ( ω t ) is constant for all eight sine waves). If I p ( ω t ) is independent of frequency, then the system under study is concluded to be reversible. Step 2. Analyse data at higher concentrations and check if I p ( ω t ) versus frequency profiles are independent of concentration. If concentration dependence is detected, check if it is consistent with the increasing importance of the IR u drop. Step 3. To determine the contribution from the IR u drop or quasi-reversibility, make initial estimates of values for parameters needed in numerical simulation. For instance, make an initial estimate of the value of E o ′ , using E o ′ = ( E p ox + E p red ) / 2 , where E p ox and E p red are the peak potentials for the oxidation and reduction currents, respectively, in the aperiodic dc component. R u can be evaluated immediately, as described in Ref. [6] , and C dl can be estimated from the magnitude of the fundamental harmonic current. In this study, initial guesses of diffusion coefficient values ( D ) are taken from the literature [6,14–16] and are 7.6 × 10 - 6 cm 2 s - 1 for FcMeOH, 8.0 × 10 - 6 cm 2 s - 1 for [ Ru ( NH 3 ) 6 ] 3 + and 6.3 × 10 - 6 cm 2 s - 1 for [ Fe ( CN ) 6 ] 3 - . In practice it was found that a value of 7.6 ± 0.5 × 10 - 6 cm 2 s - 1 could be used for all three species in 0.50 M KCl under conditions of the present study. Step 4. Compare simulations against experimental results until the level of desired accuracy is reached. Estimates of E o ′ , D and R u ( k 0 and α if required) may need to be refined by comparing simulated and experimental peak currents, and wave shapes. 2.2 Simulations We consider only the case of a macro-disk electrode: in doing so, we follow previous work [2,9,8] and invoke the assumption that diffusion is a one dimensional process. 2.2.1 Modelling the reaction mechanism The system considered is one of semi-infinite mass transport to a planar electrode where a simple reduction or oxidation reaction occurs. This type of reaction is commonly referred to as an E process and is represented as follows: (4) A + ne - ⇌ k b k f B , where both A and B are soluble in the solution phase; k f and k b are the forward and backward potential-dependent rate constants associated with Butler–Volmer kinetics [17] , given by (5) k f = k 0 ′ exp - α nF RT [ E ( t ) - E o ′ - I ( t ) R u ] , (6) k b = k 0 ′ exp ( 1 - α ) nF RT [ E ( t ) - E o ′ - I ( t ) R u ] , with E ( t ) being the applied potential (the exact form of which is described in the next paragraph), R u is the uncompensated resistance, I ( t ) is the total current and all other symbols as defined previously or as conventionally used. The number of electrons transferred in the reaction, n , may be assigned as positive or negative so that both oxidation and reduction reactions are covered by the treatment that follows. By convention, our voltammetric experiments will begin at time t = 0 : at time t < 0 the electrode is held at a constant initial potential, E i , which is sufficiently extreme to ensure that the reaction in Eq. (4) does not occur significantly. For t > 0 , the time-dependent applied potential E ( t ) has two components, a dc ramp denoted by E dc , and an oscillatory component which constitutes the ‘designer’ waveform represented by E ac = ∑ i = 1 8 Δ E i sin ( ω i t ) , where Δ E i are the amplitudes corresponding to each of the frequencies, ω i , respectively, and these obey the following relation Δ E i = Δ E 1 / ω i / ω 1 , where Δ E 1 is the amplitude of the first sine wave and ω 1 is the corresponding frequency. Note that we are using eight sine waves to mimic what has been done in the experiments. However, the theory can be applied to as many sine waves as may be desired by the user. Therefore, the potential is given by the relationship (7) E ( t ) = E dc ( t ) + E ac ( t ) , (8) = E i + vt + ∑ i = 1 8 Δ E i sin ( ω i t ) , where v is the scan rate and has the same sign as n and E i is the initial dc potential. Also we have that (9) I ( t ) = I f ( t ) + I c ( t ) , where (10) I c = AC dl d E d t , I c is referred to as the capacitive current and I f is the faradaic current (see definition in Section 2.2.2 ). Mass transport to the electrode is then modelled by a linear diffusion equation for each species ( A , B ) . If we let c A ( x , t ) and c B ( x , t ) represent the concentrations of species A and B , respectively, and let x represent the distance from the electrode surface at time t , we get the following system of equations: (11) ∂ c A ∂ t = D A ∂ 2 c A ∂ x 2 , (12) ∂ c B ∂ t = D B ∂ 2 c B ∂ x 2 , where D A and D B are the diffusion coefficients for each of the species A and B , respectively. In many studies, microelectrodes (radial diffusion dominant) are used instead of macroelectrodes (linear diffusion dominant) in order to minimise the IR u drop and the charging current. We have previously studied the effects of the use of microelectrodes in ac voltammetry [7] and have derived precise conditions under which the effects of radial diffusion can be neglected. This work demonstrates, both theoretically and experimentally, that the effects of radial diffusion are much lower in the ac voltammetry case and these features carry through directly to the designer waveform introduced in this paper. 2.2.2 Boundary conditions Given that we have made the assumption of semi-infinite linear diffusion, we have the following boundary and initial conditions: (13) at x = 0 D A ∂ c A ∂ x = - D B ∂ c B ∂ x = I f ( t ) nAF = k f c A - k b c B ; (14) as x → ∞ c A = c A ∗ , c B = 0 ; (15) and at t = 0 c A = c A ∗ , c B = 0 . Here, c A ∗ is the bulk concentration of species A and I f ( t ) is the faradaic current. Note that the equation involving I f ( t ) in Eq. (13) is derived from Fick’s first and Faraday’s laws. 2.2.3 Non-dimensional variables As has been discussed elsewhere [8,18] , we re-cast the problem in terms of non-dimensional variables: these dimensionless variables will be assigned Greek symbols in order to improve clarity. The nature of the problem implies a linear relationship between time t and the dc component of applied potential, E dc , therefore, the dimensionless symbol τ can be defined by (16) τ = F ( E init + vt - E o ′ ) / RT = F ( E dc - E o ′ ) / RT , and is used to replace both of these dimensional variables. The sine wave amplitudes Δ E i are similarly non-dimensionalised to obtain (17) Δ τ i = F Δ E i RT , whilst the angular frequency ω i becomes (18) Ω i = RT ω i Fv . This now allows us to write down a non-dimensional version of Eq. (8) , using Eqs. (16)–(18) , where ϵ ( τ ) is the non-dimensional potential (19) ϵ ( τ ) = ϵ dc ( τ ) + ϵ ac ( t ) , (20) = τ + ∑ i = 1 8 Δ τ i sin ( Ω i τ ) . Note that R u and I tot ( t ) are nondimensionalised as follows: (21) ρ u = F 2 AD A c A ∗ RT vF D A RT 1 2 R u , (22) ι tot ( τ ) = D A RT vF 1 2 I tot ( t ) AFD A c A ∗ ; faradaic and capacitive currents are non-dimensionalised in the same way as for the total current, I tot ( t ) . Finally the double layer capacitance constant is non-dimensionalised as follows: (23) γ dl = D A RT Fv 1 2 vC dl AFD A c A ∗ . 2.2.4 Numerical methods The numerical algorithm used to solve the equations in Section 2.2.1 involves backward Euler discretisations [19] , along with a simple expanding mesh in space, as described in [2] . We also make use of Brent’s method to deal with the nonlinearity introduced via the inclusion of uncompensated resistance and double layer capacitance [20] . Data analysis of simulation results is carried out in the frequency domain using Fourier analysis (via FFTs). This allows us to pick out the dc component of the signal as well as the harmonics of interest in a straightforward manner, again as described previously in [2] . The ‘decimation’ process is done in the frequency domain, where the first 2 n data points are retained and the data at higher frequencies is discarded before the inverse Fourier transform is applied. 3 Results and discussion 3.1 Experimental aspects of multi-frequency and variable amplitude ac voltammetry for a reversible process Fig. 1 illustrates the steps required for analysis of an electrode process after collection of data in the I – t format, using the multi-frequency and variable-amplitude designer waveform FT-ac voltammetry. The example presented is for the oxidation of moderately low 0.404 mM concentration of FcMeOH in aqueous 0.5 M KCl electrolyte at a GC electrode. According to literature reports [6] . FcMeOH is oxidised reversibly to [FcMeOH] + by a simple, outer-sphere, one-electron charge transfer process (24) FcMeOH ⇌ [ FcMeOH ] + + e - . Fig. 1 a demonstrates clearly that this new designer form of FT-ac voltammetry generates a vast amount of data which can be displayed in the I – t format ( Fig. 1 a and b), or as the power spectrum ( Fig. 1 c) in the frequency domain. The power spectrum provides a convenient overview of the relative significance of dc and ac terms. The ‘noisy’ nature of the power spectrum ( Fig. 1 c) implies, as expected, that this new form of ac voltammetry contains a very large amount of ac harmonic information. The dc aperiodic component ( Fig. 1 d), the fundamental ( Fig. 1 e–g), higher ac harmonics ( Fig. 1 h–m) and frequency sum and difference terms (not shown), are derived by use of the power spectrum and the inverse FT algorithm. For the medium to fairly small amplitude case used in experimental studies, the second ac harmonic component ( Fig. 1 j) may be identified at all frequencies, although the third harmonic ( Fig. 1 m) can become obscured by the system noise. In the highest frequency, minimum Δ E , case, where Δ E = 2.66 mV , the contribution from nonlinearity is minimal. In order to display the harmonic information in a clearer form, the eight fundamental harmonics can be presented in raw ( Fig. 2 a and b), decimated ( Fig. 2 c and d) and background corrected ( Fig. 2 e and f) format, which readily reveals the peak current I p ( ω t ) , values associated with each of the eight frequencies in the designer waveform. Fig. 2 d depicts the fundamental harmonic response for the eight frequencies in ac I – t format after applying the ‘decimation’ process. The result is indistinguishable from that produced by analysis of the full data set ( Fig. 2 b). A significant frequency-dependent background charging current contribution is clearly observable in the fundamental ac harmonics ( Fig. 2 b). The background current corrected results in Fig. 2 f reveal that the peak heights associated with the Faradaic process are independent of frequency, within experimental error, as predicted theoretically for a reversible process. 3.2 Simulation of the FT-ac voltammetry Simulations of the fundamental harmonic ac voltammetry obtained for a reversible process ( k 0 ′ = 10 , 000 cm s - 1 and α = 0.5 ) with the designer waveform and parameters given in Table 1 along with: R u = 0 Ω ; C dl = 0.09 F m - 2 ; E o ′ = 0.185 V ; and D = 7.6 × 10 - 6 cm 2 s - 1 ( Fig. S-1a and b ), are in excellent agreement with experimental data (provided in Fig. 2 a and b). If zero capacitance is employed instead of 0.09 F m −2 in the simulation, as is the case in Fig. S-2 , then excellent agreement is achieved with background current corrected experimental data given in Fig. 2 e and f. This result demonstrates the effectiveness of background current correction software used in this study. 3.3 Application of the designer waveform to the [FcMeOH] 0/+ process as a function of concentration Ideally, the reversible [FcMeOH] 0/+ process should exhibit I p ( ω t ) values that are independent of frequency for all concentrations, when using the designer waveform. This is true for FcMeOH concentrations ⩽0.404 mM (see Fig. S-2 for 0.404 mM case). However, less conformity to this predicted response was obtained at higher FcMeOH concentrations. In particular, significant deviation from I p ( ω t ) being independent of frequency was obtained ( Fig. 3 ) with a 2.00 mM FcMeOH solution, even though the background correction is relatively unimportant for this data set. Data obtained at ⩾1 mM FCMeOH concentration resemble that expected for a quasi-reversible process. The major factor contributing to the apparently non-reversible behaviour at higher FcMeOH concentrations is the presence of an uncompensated (Ohmic) IR u drop which becomes more important as the concentration (current) is increased. The IR u drop can lead to significant distortion in FT-ac voltammetry [13] . The predicted effect on designer-waveform FT-ac voltammetry is illustrated by simulations shown in Fig. 4 , with R u = 100 Ω . In the present experiment at a GC electrode with 0.50 M KCl as the electrolyte, R u is experimentally estimated to be 20 Ω . Simulations confirm that this value is not expected to be important at low concentrations of FcMeOH but, as found experimentally, does have an impact upon data of concentrations ⩾1 mM. For the theory of the designer waveform to be fully valid, surface interactions between FcMeOH (or [FcMeOH] + ) and the electrode should be absent. A useful method of checking for surface interaction is to compare the background current in 0.50 M KCl before and after addition of FcMeOH. As shown in Fig. S-3 , the background current at the glassy carbon electrode is reduced by a small amount after addition of 2.0 mM FcMeOH to 0.50 M KCl electrolyte. No differences in background current were detected on addition of FcMeOH concentrations ⩽0.404 mM. The implication of this result is that FcMeOH (and [FcMeOH] + ) adsorbs weakly onto a glassy carbon electrode, resulting in a small reduction in the double layer capacitance. In contrast the background current at platinum and gold electrodes in 0.50 M KCl is indistinguishable in the presence or absence of 2.0 mM FcMeOH, which indicates that FcMeOH does not adsorb at a detectable level at these electrode surfaces. Additionally, R u is only 10 Ω at these electrode surfaces compared to 20 Ω at the GC electrode so that I p ( ω t ) values at platinum or gold electrodes, even with 2.0 mM FcMeOH present, are closer to a constant than at the GC surface. Clearly, taking R u and surface interactions into account may be necessary if the use of the designer-waveform to detect reversibility is to be correctly implemented. Clearly, background current correction becomes highly critical, particularly at high frequencies and low concentrations of FcMeOH, where the background current may produce a significant component of the total current. Fig. S-4 illustrates the FT-ac voltammetry at a GC electrode in 0.50 M KCl electrolyte with 0.100 mM FcMeOH. The instrumental background current correction implemented in this work uses baseline-subtraction software in a user-interactive mode. Thus, data are chosen at user-selected times at either side of the [FcMeOH] 0/+ or other process. A polynomial fit to both data sets and interpolation to potentials in between, leads to a predicted background at potentials where a Faradaic current is present. Obviously, there is a small level of uncertainty in this approach. Fig. S-4 contains the background corrected faradaic current, for a dilute 0.100 mM FcMeOH solution using the polynomial fit derived from either 0.5–1.5 and 11–12 s, or 0–1 and 10–11 s zones for the correction of the raw data. Even with this more severe background problem than used in studies at higher concentration referred to above, excellent correction is still achieved. Traditionally, all sine waves used in multi-waveform approaches use constant values of Δ E and so the background current increases with frequency. The designer-waveform mitigates problems with large background current at higher frequencies. An alternative means of background current correction is to undertake measurements in the base electrolyte to produce the ‘blank background current file’. When 0.50 M KCl was used to produce the ‘blank background current file’ for correction of experimental data, this form of correction worked well at gold and platinum electrodes. However, it should be noted that this ‘blank background current file’ correction method is applicable only if adsorption is negligible, which is not perfectly true when high concentrations of FcMeOH are oxidised at a GC electrode. In general, the instrumental method is rapid and reliable, provided the zones used for background fitting are selected sensibly. This method is, therefore, recommended as a generally applicable and convenient approach for dealing with the background current correction. 3.4 Comparison of the designer waveform with other FT-ac methods An alternative approach to the use of the designer waveform introduced in this study is to use eight sine waves individually in eight experiments instead of simultaneously in just one experiment. I p ( ω t ) values using this single sine wave version are similar ( Fig. 5 ). However, the ability to obtain all data from a single experiment is clearly a significant advantage of the far more efficient designer waveform. Alternatively, one can employ the same frequency set as in Table 1 but with a constant amplitude for all frequencies. Data obtained from this more conventional experiment with Δ E = 15 mV for all frequencies are shown in Fig. 6 . As expected, the values of I p ( ω t ) now increase with frequency. However, the IR u drop now becomes even more significant at higher frequencies, as does the background current. Another alternative is to use a square-wave FT-ac method [9,21–23] which utilises a variable amplitude waveform at frequencies ω t , 3 ω t , 5 ω t , etc. A square-wave experiment is equivalent to applying k = ( K + 1 ) / 2 sine waves of varying amplitude where K is an odd natural number [23] . In this case, the square-wave can be written as (25) E square-wave = ∑ m = 1 , 3 k 4 Δ E m π sin ( m ω t ) , and the amplitude ( 4 Δ E / m π ) of each component ( m ω t ) clearly becomes smaller as m increases. Fig. 6 provides a comparison of I p ( ω t ) values obtained from the designer waveform, the conventional constant amplitude sinusoidal waveform and the square-wave methods of FT-ac voltammetry for oxidation of 0.404 mM FcMeOH at a GC electrode, as a function of frequency. Only I p ( ω t ) values obtained from the designer waveform are independent of frequency for a reversible process, allowing ready assignment of very fast electrode kinetics. I p ( ω t ) values obtained from the square-wave decrease with frequency as expected, while from a multi-frequency, fixed 15 mV amplitude voltammetric experiment, I p ( ω t ) increases with frequency, also as expected (approximately square root dependency). 3.5 Application of the designer waveform to other processes A more limited set of experiments were also undertaken with the designer waveform on the reduction of 0.300 mM [ Ru ( NH 3 ) 6 ] 3 + and 0.300 mM [ Fe ( CN ) 6 ] 3 - in aqueous 0.50 M KCl electrolyte. As for oxidation (the [ FcMeOH ] 0 / + process), the one-electron reduction of [ Ru ( NH 3 ) 6 ] 3 + to [ Ru ( NH 3 ) 6 ] 2 + is believed to involve a fast outer-sphere reversible electron-transfer process [4,16] . For this process, I p ( ω t ) values of background-corrected fundamental harmonic currents are close to constant at GC, platinum and gold electrodes. In this case, essentially identical background currents were obtained before and after [ Ru ( NH 3 ) 6 ] 3 + addition to 0.50 M KCl, implying that, adsorption is absent at all three electrode surfaces. Simulations based on a reversible process confirm that the reaction can be regarded as being very close to reversible with frequencies up to almost 2 kHz ( k 0 ⩾ 1 cm s - 1 ). A very different dependence of I p ( ω t ) on frequency is found for the reduction of [ Fe ( CN ) 6 ] 3 - at a GC electrode in aqueous 0.50 M KCl electrolyte ( Fig. 7 ). Data obtained at Pt or Au electrodes have quasi-reversible characteristics similar to those at GC electrodes. Comparison of background currents before and after the addition of [ Fe ( CN ) 6 ] 3 - to 0.50 M KCl electrolyte suggest adsorption is minimal at all three electrode surfaces. Simulations of a quasi-reversible process using D = 7.6 × 10 −6 cm 2 s −1 ; R u = 0 Ω, C dl = 0.15 F m −2 ; E o ′ = 0.278 V, k 0 ′ = 0.023 cm s - 1 and α = 0.5 , provided an excellent fit to experimental I p ( ω t ) values ( Fig. 8 ). Clearly, the designer waveform can be used to show departure from reversibility and then to estimate kinetic parameters for a quasi-reversible electrochemical system. Experiments have also been carried out with the designer waveform for oxidation of FcMeOH at a glassy carbon electrode in the very high resistance dichloromethane (0.10 M Bu 4 NPF 6 ) medium. The FT-ac data obtained are shown in Fig. 9 a. Simulations using parameters R u = 1100 Ω, C dl = 0.13 F m - 2 , E o ′ = - 0.154 V , with reversible electrode kinetics ( k 0 ′ = 10 , 000 cm s - 1 ; and α = 0.5 ) agree well with experimental data. Although the resistance of this medium is high, the oxidation of FcMeOH is shown to remain reversible, as found in aqueous media. However, in this case, I p ( ω t ) is not independent of frequency because of the significant contribution of the IR u drop. In this case, direct proof of reversibility is not possible via casual inspection the plot of I p ( ω t ) versus frequency. However, before assuming a process is quasi-reversible rather than reversible, studies on the concentration dependence and simulations that take R u into account must be employed. 4 Conclusions A multi-frequency, variable-amplitude ‘designer waveform’ consisting of eight sine waves of amplitude from 20 mV to about 2 mV with frequencies covering the range 35–1970 Hz has been developed to facilitate rapid assessment of the reversibility or otherwise of electrode processes by FT-ac voltammetry. With this waveform, I p ( ω t ) for the fundamental harmonic of a reversible process is predicted to be independent of frequency, provided the influence of the IR u drop is insignificant. Reversible oxidation of ferrocenemethanol (FcMeOH), reversible reduction of hexamineruthenium ( [ Ru ( NH 3 ) 6 ] 3 + ) and the quasi-reversible reduction of ferricyanide ( [ Fe ( CN ) 6 ] 3 - ) in aqueous 0.50 M KCl electrolyte have been studied at glassy-carbon, gold and platinum electrodes in order to assess the attributes of the new waveform. A major advantage of the method was found to be ready access to efficient methods for obtaining and analysing large amounts of information generated from a single experiment. Analysis of both experimental and simulated data reveals the readily recognised patterns of behaviour that enable identification of reversibility or quasi-reversibility, and contributions from uncompensated resistance and background capacitance. Excellent agreement between experimental and simulated ac voltammograms was obtained for all processes examined in aqueous 0.50 M KCl electrolyte. Provided attention is paid to the IR u drop, the waveform can also be used to confirm that oxidation of FcMeOH is reversible in highly resistive dichloromethane solvent. Acknowledgement Financial support from the Australian Research Council is gratefully acknowledged. Appendix A Supplementary material Figs. S-1 to S-4 contain ac voltammetric data. Supplementary data associated with this article can be found, in the online version, at doi:10.1016/j.jelechem.2009.07.007 . Appendix A Supplementary material fx1 (a) I – t data simulated to mimic experimental data displayed in 2a. (b) FT-recovered fundamental harmonics simulated to mimic experimental data displayed in Fig. 2b. Parameters used in simulation of a reversible process are provided in the text. fx2 (a) I – t , (b) fundamental harmonic, data simulated with zero background current in order to mimic experimental data displayed in Fig. 2e and f. Parameters used to simulate the reversible process are provided in the text and as for Fig. S-1 except C dl = 0 F m - 2 . fx3 Comparison of fundamental harmonic background currents before and after addition of FcMeOH. (a) I ( ωt ) versus t data at GC electrode in 0.5 M KCl. (b) As for (a) but after addition of 2.0 mM FcMeOH. (c) Comparison of fundamental harmonic background currents before and after FcMeOH addition. fx4 (a) Raw current versus time data obtained when 0.100 mM FcMeOH is oxidised at a GC electrode in 0.50 M KCl electrolyte. (b and c) Background corrected current using different designated time regimes: (b) with 0.5–1.5 and 11–12 s, and (c) with 0–1 and 10–11 s correction reference zones. References [1] S.O. Engblom J.C. Myland K.B. Oldham J. Electroanal. Chem. 480 2000 120 [2] D.J. Gavaghan A.M. Bond J. Electroanal. Chem. 480 2000 133 [3] D.E. Smith Electroanalytical Chemistry: A Series of Advances Vol. 1 1966 Marcal Dekker New York [4] J. Zhang S. Guo A.M. Bond Anal. Chem. 76 2004 3619 [5] S. Guo J. Zhang D. Elton A.M. Bond Anal. Chem. 76 2004 166 [6] B. Lertanantawong A.P. O’Mullane J. Zhang W. Surareungchai M. Somasundrum A.M. Bond Anal. Chem. 80 2008 6515 [7] D.J. Gavaghan D.M. Elton A.M. Bond Collect. Czech. Chem. Commun. 66 2001 255 [8] D.J. Gavaghan D. Elton A.M. Bond J. Electroanal. Chem. 513 2001 73 [9] D.J. Gavaghan D. Elton K.B. Oldham A.M. Bond J. Electroanal. Chem. 512 2001 1 [10] M. Rosvall M. Sharp Electrochem. Commun. 2 2000 338 [11] J. Hàzí D.M. Elton W.A. Czerwinski V.A. Vicente-Beckett A.M. Bond J. Electroanal. Chem. 437 1997 1 [12] J. Schiewe J. Hàzí V.A. Vicente-Beckett A.M. Bond J. Electroanal. Chem. 451 1998 129 [13] A.M. Bond N.W. Duffy S. Guo J. Zhang D. Elton Anal. Chem. 77 2005 186A [14] M.P. Longinotti H.R. Corti Electrochem. Commun. 9 2007 1444 [15] C. Cannes F. Kanoufi A.J. Bard J. Electroanal. Chem. 547 2003 83 [16] M. Pyo A.J. Bard Electrochim. Acta 42 1997 3077 [17] A.J. Bard L.R. Faulkner Electrochemical Methods 2nd ed. 2001 Wiley New York [18] D.J. Gavaghan A.M. Bond Electroanalysis 18 2006 333 [19] K.W. Morton D.F. Mayers Numerical Solution of Partial Differential Equations 1994 Cambridge University Press Cambridge [20] R. Brent Algorithms for Minimization without Derivatives 1973 Prentice Hall England [21] A.A. Sher A.M. Bond D.J. Gavaghan K. Harriman S.W. Feldberg N.W. Duffy Anal. Chem. 76 2004 6214 [22] A.M. Bond Modern Polarographic Methods in Analytical Chemistry 1980 Marcel Dekker New York [23] A.A. Sher A.M. Bond D.J. Gavaghan K. Gillow N.W. Duffy S. Guo J. Zhang Electroanalysis 17 2005 1450",
        "keywords": [
            "fourier transform",
            "high frequency"
        ],
        "authors": [
            {
                "name": "Yongjun Tan",
                "org": ""
            },
            {
                "name": "Gareth P. Stevenson",
                "org": "Oxford University Computing Laboratory, Wolfson Building, Parks Road, Oxford, OX1 3QD, United Kingdom"
            },
            {
                "name": "Ruth E. Baker",
                "org": "Centre for Mathematical Biology, Mathematical Institute, 24-29 St. Giles’, Oxford OX1 3LB, United Kingdom"
            },
            {
                "name": "Darrell Elton",
                "org": "Department of Electronic Engineering, Latrobe University, Bundoora, Victoria 3083, Australia"
            },
            {
                "name": "Kathryn Gillow",
                "org": "Oxford University Computing Laboratory, Wolfson Building, Parks Road, Oxford, OX1 3QD, United Kingdom"
            },
            {
                "name": "Jie Zhang",
                "org": "Institute of Bioengineering and Nanotechnology, 31 Biopolis Way, The Nanos, 138669, Singapore"
            },
            {
                "name": "Alan M. Bond",
                "org": ""
            },
            {
                "name": "David J. Gavaghan",
                "org": ""
            }
        ],
        "venue": "Journal of Electroanalytical Chemistry",
        "year": 2009
    },
    "2ZBn53Z9": {
        "id": "2ZBn53Z9",
        "title": "Ultrasensitive electrochemical DNA biosensors based on the detection of a highly characteristic solid-state process.",
        "abstract": "",
        "keywords": [
            "bird flu virus",
            "dna",
            "silver nanoparticles",
            "biosensors"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Boon Ping Ting",
                "org": ""
            },
            {
                "name": "Nikhil R Jana",
                "org": ""
            },
            {
                "name": "Zhiqiang Gao",
                "org": ""
            },
            {
                "name": "Jackie Y Ying",
                "org": ""
            }
        ],
        "venue": "Small (Weinheim an der Bergstrasse, Germany)",
        "year": 2009
    },
    "Y0YqRL1p": {
        "id": "Y0YqRL1p",
        "title": "Pt nanoparticle label-mediated deposition of Pt catalyst for ultrasensitive electrochemical immunosensors.",
        "abstract": "Herein we describe a novel signal amplification strategy for the development of ultrasensitive electrochemical immunosensors. The amplification strategy is based on platinum catalyzing a hydrogen evolution reaction. To demonstrate its practicality, the electrochemical signal enhancement strategy has been applied for the development of a novel prostate-specific antigen (PSA) immunosensor. The immunosensing protocol utilized a gold electrode with PSA capture antibodies bound to its surface via covalent bonding. After PSA was bound to the electrode surface, a secondary platinum nanoparticle-labeled detection antibody was used to complete the sandwich immunosensor. The resulting electrode was then dipped in a platinum developer solution containing 1 mM of PtCl4(2-), 0.1M of formate (reductant) and 0.5% Tween 80 (pH 6.5) to generate bare platinum catalysts in close proximity to the Au electrode surface through a seed-mediated nucleation and growth mechanism. The signal readout was obtained electrochemically via a Pt-catalyzed hydrogen evolution reaction in an acidic aqueous medium containing 10 mM of HCl and 1 M of KCl. A detection limit of 1 fg/ml was achieved.",
        "keywords": [
            "detection limit"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Institute of Bioengineering and Nanotechnology, 31 Biopolis Way, The Nanos, #04-01, Singapore 138669, Singapore"
            },
            {
                "name": "Boon Ping Ting",
                "org": "Institute of Bioengineering and Nanotechnology, 31 Biopolis Way, The Nanos, #04-01, Singapore 138669, Singapore"
            },
            {
                "name": "Majad Khan",
                "org": "Institute of Bioengineering and Nanotechnology, 31 Biopolis Way, The Nanos, #04-01, Singapore 138669, Singapore"
            },
            {
                "name": "Mark C Pearce",
                "org": "Institute of Bioengineering and Nanotechnology, 31 Biopolis Way, The Nanos, #04-01, Singapore 138669, Singapore"
            },
            {
                "name": "Yiyan Yang",
                "org": "Institute of Bioengineering and Nanotechnology, 31 Biopolis Way, The Nanos, #04-01, Singapore 138669, Singapore"
            },
            {
                "name": "Zhiqiang Gao",
                "org": "Institute of Bioengineering and Nanotechnology, 31 Biopolis Way, The Nanos, #04-01, Singapore 138669, Singapore"
            },
            {
                "name": "Jackie Y Ying",
                "org": ""
            }
        ],
        "venue": "Biosensors & bioelectronics",
        "year": 2010
    },
    "FrNdWC7S": {
        "id": "FrNdWC7S",
        "title": "Voltammetric ion-selective electrodes for the selective determination of cations and anions.",
        "abstract": "A general theory has been developed for voltammetric ion sensing of cations and anions based on the use of an electrode coated with a membrane containing an electroactive species, an ionophore, and a supporting electrolyte dissolved in a plasticizer. In experimental studies, a membrane coated electrode is fabricated by the drop coating method. In one configuration, a glassy carbon electrode is coated with a poly(vinyl chloride) based membrane, which contains the electroactive species, ionophore, plasticizer and supporting electrolyte. In the case of a cation sensor, ionophore facilitated transfer of the target cation from the aqueous solution to the membrane phase occurs during the course of the reduction of the electroactive species present in the membrane in order to maintain charge neutrality. The formal potential is calculated from the cyclic voltammogram as the average of the reduction and oxidation peak potentials and depends on the identity and concentration of the ion present in the aqueous solution phase. A plot of the formal potential versus the logarithm of the concentration exhibits a close to Nernstian slope of RT/F millivolts per decade change in concentration when the concentration of K(+) and Na(+) is varied over the concentration range of 0.1 mM to 1 M when K(+) or Na(+) ionophores are used in the membrane. The slope is close to RT/2F millivolts for a Ca(2+) voltammetric ion-selective electrode fabricated using a Ca(2+) ionophore. The sensor measurement time is only a few seconds. Voltammetric sensors for K(+), Na(+), and Ca(2+) constructed in this manner exhibit the sensitivity and selectivity required for determination of these ions in environmentally and biologically important matrixes. Analogous principles apply to the fabrication of anion voltammetric sensors.",
        "keywords": [
            "innovative"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Alexander R Harris",
                "org": ""
            },
            {
                "name": "Robert W Cattrall",
                "org": ""
            },
            {
                "name": "Alan M Bond",
                "org": ""
            }
        ],
        "venue": "Analytical chemistry",
        "year": 2010
    },
    "wsb6XW3j": {
        "id": "wsb6XW3j",
        "title": "Electrode Kinetics Associated with Tetracyanoquinodimethane (TCNQ), TCNQ •– , and TCNQ 2– Redox Chemistry in Acetonitrile As Determined by Analysis of Higher Harmonic Components Derived from Fourier Transformed Large Amplitude ac Voltammetry",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "inamulhaque",
                "org": ""
            },
            {
                "name": "alan m bond",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "ayman nafady",
                "org": ""
            },
            {
                "name": "kiran bano",
                "org": ""
            }
        ],
        "venue": "Journal of Physical Chemistry C",
        "year": 2011
    },
    "WyLJ0UZn": {
        "id": "WyLJ0UZn",
        "title": "A unique proton coupled electron transfer pathway for electrochemical reduction of acetophenone in the ionic liquid [BMIM][BF4] under a carbon dioxide atmosphere",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "shufeng zhao",
                "org": "east china normal university"
            },
            {
                "name": "laxia wu",
                "org": "east china normal university"
            },
            {
                "name": "huan wang",
                "org": "east china normal university"
            },
            {
                "name": "jiaxing lu",
                "org": "east china normal university"
            },
            {
                "name": "alan m bond",
                "org": "monash university clayton campus"
            },
            {
                "name": "jie zhang",
                "org": "monash university clayton campus"
            }
        ],
        "venue": "Green Chemistry",
        "year": 2011
    },
    "u27UI3hR": {
        "id": "u27UI3hR",
        "title": "ChemInform Abstract: Synthesis of Metallic Nanoparticles Using Electrogenerated Reduced Forms of [α-SiW 12 O 40 ] 4- as Both Reductants and Stabilizing Agents.",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "jackie y ying",
                "org": ""
            },
            {
                "name": "yan tong koh",
                "org": ""
            },
            {
                "name": "boon ping ting",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            }
        ],
        "venue": "Cheminform",
        "year": 2011
    },
    "Hw4Fhwo4": {
        "id": "Hw4Fhwo4",
        "title": "METHODS AND COMPOSITIONS COMPRISING POLYOXOMETALATES",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "jackie y ying",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "boon ping ting",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2011
    },
    "VjiuJwjj": {
        "id": "VjiuJwjj",
        "title": "A unique proton coupled electron transfer pathway for electrochemical reduction of acetophenone in the ionic liquid [BMIM][BF 4] under a carbon dioxide atmosphere",
        "abstract": "The mechanism of electrochemical reduction of acetophenone in 1-butyl-3-methylimidazolium tetrafluroborate ([BMIM][BF 4]) under nitrogen (N 2) and carbon dioxide (CO 2) atmospheres have been investigated using transient voltammetry, steady-state voltammetry, bulk electrolysis and numerical simulation. Under a N 2 atmosphere, acetophenone undergoes a one-electron reduction to the radical anion followed by rapid dimerization reactions with an apparent rate constant of 1.0 × 10 6 M -1 s -1. In contrast, under a CO 2 atmosphere, the electrochemical reduction of acetophenone is an overall two-electron transfer chemically irreversible process with the final electrolysis product being 1-phenylethanol, instead of the anticipated 2-hydroxy-2-phenylpropionic acid resulting from an electrocarboxylation reaction. A proton coupled electron transfer pathway leading to the formation of 1-phenylethanol requires the presence of a sufficiently strong proton donor which is not available in neat [BMIM][BF 4]. However, the presence of CO 2 enhances the C-2 hydrogen donating ability of [BMIM] + due to strong complex formation between the deprotonated form of [BMIM] +, N-heterocyclic carbene, and CO 2, resulting in a thermodynamically favorable proton coupled electron transfer pathway. © 2011 The Royal Society of Chemistry.",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "ShuFeng Zhao",
                "org": "East China Normal University(East China Normal University),Shanghai,China"
            },
            {
                "name": "LaXia Wu",
                "org": "East China Normal University(East China Normal University),Shanghai,China"
            },
            {
                "name": "Huan WANG",
                "org": "East China Normal University(East China Normal University),Shanghai,China"
            },
            {
                "name": "Jiaxing Lu",
                "org": "East China Normal University(East China Normal University),Shanghai,China"
            },
            {
                "name": "Alan M. Bond",
                "org": "Monash University(Monash University),Melbourne,Australia"
            },
            {
                "name": "Jie Zhang",
                "org": "Monash University(Monash University),Melbourne,Australia"
            }
        ],
        "venue": "Green Chemistry",
        "year": 2011
    },
    "w5WHxPc0": {
        "id": "w5WHxPc0",
        "title": "Ultrasensitive electrochemical immunosensor employing glucose oxidase catalyzed deposition of gold nanoparticles for signal amplification.",
        "abstract": "This paper describes a novel enzymatic amplification strategy for ultrasensitive electrochemical immunosensing. This approach utilizes glucose oxidase for the enzymatic deposition of gold nanoparticles onto an indium tin oxide (ITO) electrode surface using a novel gold developer solution consisting of 20 mM of glucose, 20 mM of NaSCN, 0.5 M of p-benzoquinone (PBQ) and 1 mM of AuCl(4)(-) dissolved in 0.1 M of pH 7.5 phosphate buffer solution. The amount of gold deposited was quantified electrochemically by monitoring the reduction of gold oxide in an aqueous solution of 0.5 M of H(2)SO(4), which was correlated to the amount of antigens in the solution. The effectiveness of this strategy was demonstrated experimentally through the construction of an immunosensor for the detection of mouse IgG using a sandwich immunoassay in a linear dynamic range of 5 pg/ml to 50 ng/ml. A good mean apparent recovery in the range of 88-102% was obtained over the entire linear dynamic range of the sensor response in the serum samples. This suggested that the immunosensor would be useful for the testing of proteins in real clinical samples.",
        "keywords": [
            "phosphate buffer solution",
            "indium tin oxide",
            "dynamic range",
            "gold nanoparticles",
            "aqueous solution"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Institute of Bioengineering and Nanotechnology, 31 Biopolis Way, The Nanos, Singapore 138669, Singapore"
            },
            {
                "name": "Mark C Pearce",
                "org": "Institute of Bioengineering and Nanotechnology, 31 Biopolis Way, The Nanos, Singapore 138669, Singapore"
            },
            {
                "name": "Boon Ping Ting",
                "org": "Institute of Bioengineering and Nanotechnology, 31 Biopolis Way, The Nanos, Singapore 138669, Singapore"
            },
            {
                "name": "Jackie Y Ying",
                "org": ""
            }
        ],
        "venue": "Biosensors & bioelectronics",
        "year": 2011
    },
    "C0fYtYcX": {
        "id": "C0fYtYcX",
        "title": "Voltammetric studies in “wet” 1-butyl-1-methylpyrrolidinium bis(trifluoromethylsulfonyl)imide ionic liquid using electrodes with adhered microparticles",
        "abstract": "",
        "keywords": [
            "water",
            "ionic liquids"
        ],
        "authors": [
            {
                "name": "shufeng zhao",
                "org": ""
            },
            {
                "name": "jiaxing lu",
                "org": ""
            },
            {
                "name": "alan m bond",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            }
        ],
        "venue": "Electrochemistry Communications",
        "year": 2012
    },
    "s2U58fMC": {
        "id": "s2U58fMC",
        "title": "Simplifying the Evaluation of Graphene Modified Electrode Performance Using Rotating Disk Electrode Voltammetry",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "alan m bond",
                "org": ""
            },
            {
                "name": "shufeng zhao",
                "org": ""
            },
            {
                "name": "sixuan guo",
                "org": ""
            }
        ],
        "venue": "Langmuir",
        "year": 2012
    },
    "ao4Fmok4": {
        "id": "ao4Fmok4",
        "title": "ChemInform Abstract: Synthesis of Metallic Nanoparticles Using Electrogenerated Reduced Forms of [α‐SiW12O40]4‐ as Both Reductants and Stabilizing Agents.",
        "abstract": "",
        "keywords": [
            "nanotechnology"
        ],
        "authors": [
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "boon ping ting",
                "org": ""
            },
            {
                "name": "yan tong koh",
                "org": ""
            },
            {
                "name": "jackie y ying",
                "org": ""
            }
        ],
        "venue": "Cheminform",
        "year": 2012
    },
    "iauTPdg4": {
        "id": "iauTPdg4",
        "title": "Detailed Electrochemical Studies of the Tetraruthenium Polyoxometalate Water Oxidation Catalyst in Acidic Media: Identification of an Extended Oxidation Series using Fourier Transformed Alternating Current Voltammetry",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "yurii v geletii",
                "org": ""
            },
            {
                "name": "craig l hill",
                "org": ""
            },
            {
                "name": "guibo zhu",
                "org": ""
            },
            {
                "name": "alan m bond",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "timothy mccormac",
                "org": ""
            },
            {
                "name": "chongyong lee",
                "org": ""
            },
            {
                "name": "sixuan guo",
                "org": ""
            },
            {
                "name": "aidan fagan murphy",
                "org": ""
            }
        ],
        "venue": "Inorganic Chemistry",
        "year": 2012
    },
    "pfrM583o": {
        "id": "pfrM583o",
        "title": "Graphene-supported [{Ru4O4(OH)2(H2O)4}(γ-SiW10O36)2]10− for highly efficient electrocatalytic water oxidation",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "sixuan guo",
                "org": "monash university clayton campus"
            },
            {
                "name": "yuping liu",
                "org": "monash university clayton campus"
            },
            {
                "name": "chongyong lee",
                "org": "monash university clayton campus"
            },
            {
                "name": "alan m bond",
                "org": "monash university clayton campus"
            },
            {
                "name": "jie zhang",
                "org": "monash university clayton campus"
            },
            {
                "name": "yurii v geletii",
                "org": "emory university"
            },
            {
                "name": "craig l hill",
                "org": "emory university"
            }
        ],
        "venue": "Energy and Environmental Science",
        "year": 2013
    },
    "d8BN5DKN": {
        "id": "d8BN5DKN",
        "title": "On choosing a reference redox system for electrochemical measurements: a cautionary tale",
        "abstract": "Abstract The potential of a quasi-reference electrode can be determined by introducing an internal reference redox system (IRRS) which comprises either the oxidizable or reducible form of a reversible (and, ideally, outer-sphere) redox couple and then observing the cyclic voltammetric responses. The objective is to choose the IRRS so that the cyclic voltammetric response for the simultaneously present electroactive analyte system (ANS) can be observed independently of the IRRS response. We identify three fundamental paradigms describing the relative positioning of the IRRS and ANS on the potential scale, the operative redox components for the IRRS and ANS, and the starting potential (E start), reversing potential (E rev), and ending potential (E end) for the cyclic voltammetric scan as follows: paradigm A, an optimal paradigm which can produce completely independent cyclic voltammetric responses for the IRRS or for ANS; paradigm B, a less-than-optimal paradigm which can produce an independent cyclic voltammetry (CV) response for the ANS or a mixed response for the IRRS with that response on top of the ANS response; paradigm C, a problematic paradigm that can produce an independent CV response for the IRRS or a mixed response for the ANS with that response on top of the IRRS response; and any mixed response produces a thermodynamically favored redox cross-reaction which couples the IRRS and ANS systems and which can complicate the analysis of the ANS and IRRS responses. The conclusion is that paradigm C is to be avoided.",
        "keywords": [
            "Cyclic voltammetry",
            "Internal reference redox system",
            "Analyte system",
            "Potential zone",
            "Quasi-reference electrode",
            "QRE",
            "Cross-reaction",
            "Midpoint potential",
            "Formal potential"
        ],
        "authors": [
            {
                "name": "Angel A. J. Torriero",
                "org": "Institute for Frontier Materials, Deakin University, Burwood, Melbourne, VIC, 3125, Australia"
            },
            {
                "name": "Stephen W. Feldberg",
                "org": "Chemistry Department, Brookhaven National Laboratory, Upton, NY, 11973, USA ; School of Chemistry, Monash University, Clayton, Melbourne, VIC, 3800, Australia"
            },
            {
                "name": "Jie Zhang",
                "org": "School of Chemistry, Monash University, Clayton, Melbourne, VIC, 3800, Australia"
            },
            {
                "name": "Alexandr N. Simonov",
                "org": "School of Chemistry, Monash University, Clayton, Melbourne, VIC, 3800, Australia"
            },
            {
                "name": "Alan M. Bond",
                "org": "School of Chemistry, Monash University, Clayton, Melbourne, VIC, 3800, Australia"
            }
        ],
        "venue": "Journal of Solid State Electrochemistry",
        "year": 2013
    },
    "3ZZzBylf": {
        "id": "3ZZzBylf",
        "title": "Applications of voltammetric ion selective electrodes to complex matrices",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "alexander r harris",
                "org": "monash university clayton campus"
            },
            {
                "name": "jie zhang",
                "org": "monash university clayton campus"
            },
            {
                "name": "robert w cattrall",
                "org": "la trobe university"
            },
            {
                "name": "alan m bond",
                "org": "monash university clayton campus"
            }
        ],
        "venue": "Analytical Methods",
        "year": 2013
    },
    "eIdhbGYp": {
        "id": "eIdhbGYp",
        "title": "Voltammetric determination of the reversible potentials for [{Ru4O4(OH)2(H2O)4}(γ-SiW10O36)2]10- over the pH range of 2-12: electrolyte dependence and implications for water oxidation catalysis.",
        "abstract": "Voltammetric studies of the Ru-containing polyoxometalate water oxidation molecular catalyst [{Ru4O4(OH)2(H2O)4}(γ-SiW10O36)2](10-) ([1(γ-SiW10O36)2](10-) where 1 represents the {Ru4O4(OH)2(H2O)4} core and 1(0) stands for its initial form with all ruthenium centers in the oxidation state IV) have been carried out in aqueous media over a wide range of pH (2-12 using Britton-Robinson buffer) and ionic strength. Well-defined voltammograms in buffered media are only obtained when Frumkin double layer effects are suppressed by the presence of a sufficient concentration of additional supporting electrolyte (LiNO3, NaNO3, KNO3, Ca(NO3)2, Mg(NO3)2, MgSO4, or Na2SO4). A combination of data derived from dc cyclic, rotating disk electrode, and Fourier transformed large amplitude ac voltammetry allow the assignment of two processes related to reduction of the framework and the complete series of Ru(III/IV) and Ru(IV/V) redox processes and also provide their reversible potentials. Analysis of these data reveals that K(+) has a significantly stronger interaction with 1(1) (the number inside bracket stands for the number of electrons removed from 1(0)) than found for the other cations investigated, and hence its presence significantly alters the pH dependence of the 1(0)/1(1) reversible potential. Comparison of experimental data with theory developed in terms of equilibrium constants for process 1(0)/1(1) reveals that both H(+) and K(+) interact competitively with both 1(0) and 1(1). Importantly, reversible potential data reveal that (i) proton transfer does not necessarily need to be coupled to all electron transfer steps to achieve catalytic oxidation of water, (ii) the four-electron oxidized form, 1(4), is capable of oxidizing water under all conditions studied, and (iii) under some conditions, the three-electron oxidized form, 1(3), also exhibits considerable catalytic activity.",
        "keywords": [],
        "authors": [
            {
                "name": "Yuping Liu",
                "org": "School of Chemistry, Monash University , Clayton, Victoria 3800 Australia."
            },
            {
                "name": "Si-Xuan Guo",
                "org": ""
            },
            {
                "name": "Alan M Bond",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Yurii V Geletii",
                "org": ""
            },
            {
                "name": "Craig L Hill",
                "org": ""
            }
        ],
        "venue": "Inorganic chemistry",
        "year": 2013
    },
    "IgGVnHNA": {
        "id": "IgGVnHNA",
        "title": "Synthesis, characterization and morphology of reduced graphene oxide–metal–TCNQ nanocomposites",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "edson nossol",
                "org": "federal university of parana"
            },
            {
                "name": "arlene b s nossol",
                "org": "monash university clayton campus"
            },
            {
                "name": "sixuan guo",
                "org": "monash university clayton campus"
            },
            {
                "name": "jie zhang",
                "org": "monash university clayton campus"
            },
            {
                "name": "xiya fang",
                "org": "monash university"
            },
            {
                "name": "aldo j g zarbin",
                "org": "federal university of parana"
            },
            {
                "name": "alan m bond",
                "org": "monash university clayton campus"
            }
        ],
        "venue": "",
        "year": 2014
    },
    "VKCdUOPp": {
        "id": "VKCdUOPp",
        "title": "Investigations of Fast Electrode Kinetics for Reduction of 2,3,5,6-Tetrafluoro-7,7,8,8-tetracyanoquinodimethane in Conventional Solvents and Ionic Liquids Using Fourier Transformed Large Amplitude Alternating Current Voltammetry",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "kiran bano",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "alan m bond",
                "org": ""
            }
        ],
        "venue": "Journal of Physical Chemistry C",
        "year": 2014
    },
    "nls7FUMc": {
        "id": "nls7FUMc",
        "title": "Direct Electrodeposition of Graphene‐Gold Nanocomposite Films for Ultrasensitive Voltammetric Determination of Mercury(II)",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "liang ding",
                "org": "monash university clayton campus"
            },
            {
                "name": "yuping liu",
                "org": "monash university clayton campus"
            },
            {
                "name": "jianping zhai",
                "org": "nanjing university"
            },
            {
                "name": "alan m bond",
                "org": "monash university clayton campus"
            },
            {
                "name": "jie zhang",
                "org": "monash university clayton campus"
            }
        ],
        "venue": "Electroanalysis",
        "year": 2014
    },
    "wF0lRvwq": {
        "id": "wF0lRvwq",
        "title": "Electrocarboxylation of acetophenone in ionic liquids: the influence of proton availability on product distribution",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "shufeng zhao",
                "org": "commonwealth scientific and industrial research organisation"
            },
            {
                "name": "michael d horne",
                "org": "commonwealth scientific and industrial research organisation"
            },
            {
                "name": "alan m bond",
                "org": "monash university clayton campus"
            },
            {
                "name": "jie zhang",
                "org": "monash university clayton campus"
            }
        ],
        "venue": "Green Chemistry",
        "year": 2014
    },
    "Pvbdxd8O": {
        "id": "Pvbdxd8O",
        "title": "Electrode reaction and mass-transport mechanisms associated with the Iodide/Triiodide Couple in the Ionic Liquid 1-Ethyl-3-methylimidazolium Bis(trifluoromethanesulfonyl)imide",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "cameron l bentley",
                "org": ""
            },
            {
                "name": "alan m bond",
                "org": ""
            },
            {
                "name": "anthony f hollenkamp",
                "org": ""
            },
            {
                "name": "peter j mahon",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            }
        ],
        "venue": "Journal of Physical Chemistry C",
        "year": 2014
    },
    "UOKzSmvr": {
        "id": "UOKzSmvr",
        "title": "ChemInform Abstract: Mediator Enhanced Water Oxidation Using Rb4[RuII(bipy)3]5 [{RuIII4O4(OH)2 (H2O)4} (γ‐SiW10O36)2] Film Modified Electrodes.",
        "abstract": "",
        "keywords": [
            "energy conversion"
        ],
        "authors": [
            {
                "name": "sixuan guo",
                "org": "monash university clayton campus"
            },
            {
                "name": "chongyong lee",
                "org": "monash university clayton campus"
            },
            {
                "name": "jie zhang",
                "org": "monash university clayton campus"
            },
            {
                "name": "alan m bond",
                "org": "monash university clayton campus"
            },
            {
                "name": "yurii v geletii",
                "org": "monash university clayton campus"
            },
            {
                "name": "craig l hill",
                "org": "monash university clayton campus"
            }
        ],
        "venue": "Cheminform",
        "year": 2014
    },
    "51qvvU4G": {
        "id": "51qvvU4G",
        "title": "Electrochemistry of nickel(II) and copper(II) -ethylenebis(acetylacetoniminato) complexes and their electrocatalytic activity for reduction of carbon dioxide and carboxylic acid protons",
        "abstract": "The effect of the metal center of [ML] complexes [M = Ni(II), Cu(II); L = -ethylenebis(acetylacetoniminato)] on their electrochemistry and electrocatalytic activity for the reduction of CO and protons has been studied using cyclic voltammetry and bulk electrolysis. The two complexes exhibit different electrochemistries, which are not significantly dependent on the nature of the solvent. The electrocatalytic activity of [NiL] is significantly higher than that of [CuL] for CO reduction, due to the higher stability of the electrochemically generated [Ni(I)L] complex, relative to the Cu(I) analog. The diffusion coefficient of [NiL] calculated from the steady-state diffusion limiting current is 3.0 × 10 cm s. The catalytic efficiency of [NiL] in non-aqueous solvents in terms of  (CO)/ (N) per nickel center is smaller than that of [Ni(cyclam)], but greater than those of sterically hindered mononuclear [Ni(1,3,6,8,10, 13,15-heptaazatricyclo(11.3.1.1) octadecane)] or multinuclear [Ni X] where X = 8,8′,8″-{2,2′,2″(-nitrilotriethyl)-tris(1,3,6,8,10,13,15-heptaazatricyclo(11.3.1.1) octadecane}. Both [NiL] and [CuL] are also electrocatalysts for the reduction of carboxylic acid protons, with the catalytic pathway being different for acetic and trifluoroacetic acids in MeCN.",
        "keywords": [
            "Ionic Liquid",
            "MeCN",
            "Electrocatalytic Activity",
            "Metal Hydride",
            "Octadecane"
        ],
        "authors": [
            {
                "name": "Manawadevi Y. Udugala-Ganehenege",
                "org": "Department of Chemistry, Faculty of Science,University of Peradeniya,Peradeniya,Sri LankaPost-Graduate Institute of Science,University of Peradeniya,Peradeniya,Sri Lanka"
            },
            {
                "name": "N. M. Dissanayake",
                "org": "Post-Graduate Institute of Science,University of Peradeniya,Peradeniya,Sri Lanka"
            },
            {
                "name": "Yuping Liu",
                "org": "School of Chemistry,Monash University,Clayton,Australia"
            },
            {
                "name": "Alan M. Bond",
                "org": "School of Chemistry,Monash University,Clayton,Australia"
            },
            {
                "name": "Jie Zhang",
                "org": "School of Chemistry,Monash University,Clayton,Australia"
            }
        ],
        "venue": "Transition Metal Chemistry",
        "year": 2014
    },
    "0yuSPVYR": {
        "id": "0yuSPVYR",
        "title": "Applications of Convolution Voltammetry in Electroanalytical Chemistry",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "cameron l bentley",
                "org": ""
            },
            {
                "name": "alan m bond",
                "org": ""
            },
            {
                "name": "anthony f hollenkamp",
                "org": ""
            },
            {
                "name": "peter j mahon",
                "org": ""
            }
        ],
        "venue": "Analytical Chemistry",
        "year": 2014
    },
    "ADykgsOk": {
        "id": "ADykgsOk",
        "title": "Phosphomolybdate@poly(diallyldimethylammonium chloride)-reduced graphene oxide modified electrode for highly efficient electrocatalytic reduction of bromate",
        "abstract": "",
        "keywords": [
            "graphene",
            "electrocatalysis"
        ],
        "authors": [
            {
                "name": "liang ding",
                "org": ""
            },
            {
                "name": "yuping liu",
                "org": ""
            },
            {
                "name": "sixuan guo",
                "org": ""
            },
            {
                "name": "jianping zhai",
                "org": ""
            },
            {
                "name": "alan m bond",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            }
        ],
        "venue": "Journal of Electroanalytical Chemistry",
        "year": 2014
    },
    "Ih7cZSjj": {
        "id": "Ih7cZSjj",
        "title": "Electroless deposition of iridium oxide nanoparticles promoted by condensation of [Ir(OH)6]2− on an anodized Au surface: application to electrocatalysis of the oxygen evolution reaction",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "p esakki karthik",
                "org": "council of scientific and industrial research"
            },
            {
                "name": "k alagar raja",
                "org": "council of scientific and industrial research"
            },
            {
                "name": "saten kumar",
                "org": "council of scientific and industrial research"
            },
            {
                "name": "k l n phani",
                "org": "council of scientific and industrial research"
            },
            {
                "name": "yuping liu",
                "org": "monash university clayton campus"
            },
            {
                "name": "sixuan guo",
                "org": "monash university clayton campus"
            },
            {
                "name": "jie zhang",
                "org": "monash university clayton campus"
            },
            {
                "name": "alan m bond",
                "org": "monash university clayton campus"
            }
        ],
        "venue": "",
        "year": 2014
    },
    "UGpgnU5O": {
        "id": "UGpgnU5O",
        "title": "Mass transport studies and hydrogen evolution at a platinum electrode using bis(trifluoromethanesulfonyl)imide as the proton source in ionic liquids and conventional solvents",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "cameron l bentley",
                "org": ""
            },
            {
                "name": "alan m bond",
                "org": ""
            },
            {
                "name": "anthony f hollenkamp",
                "org": ""
            },
            {
                "name": "peter j mahon",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            }
        ],
        "venue": "Journal of Physical Chemistry C",
        "year": 2014
    },
    "YZbtsDzf": {
        "id": "YZbtsDzf",
        "title": "Fourier‐Transformed Large‐Amplitude AC Voltammetric Study of Tetrathiafulvalene (TTF): Electrode Kinetics of the TTF0/TTF.+ and TTF.+/TTF2+ Processes",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "alan m bond",
                "org": "monash university clayton campus"
            },
            {
                "name": "kiran bano",
                "org": "monash university clayton campus"
            },
            {
                "name": "shaimaa adeel",
                "org": "monash university clayton campus"
            },
            {
                "name": "lisandra l martin",
                "org": "monash university clayton campus"
            },
            {
                "name": "jie zhang",
                "org": "monash university clayton campus"
            }
        ],
        "venue": "",
        "year": 2014
    },
    "FvXj4ZVo": {
        "id": "FvXj4ZVo",
        "title": "ChemInform Abstract: Mediator Enhanced Water Oxidation Using Rb 4 [Ru II (bipy) 3 ] 5 [{Ru III 4 O 4 (OH) 2 (H 2 O) 4 } (γ-SiW 10 O 36 ) 2 ] Film Modified Electrodes.",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "yurii v geletii",
                "org": ""
            },
            {
                "name": "craig l hill",
                "org": ""
            },
            {
                "name": "sixuan guo",
                "org": ""
            },
            {
                "name": "chongyong lee",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "alan m bond",
                "org": ""
            }
        ],
        "venue": "Cheminform",
        "year": 2014
    },
    "m1QWLDaT": {
        "id": "m1QWLDaT",
        "title": "Synthesis, characterization, crystal structure, electrochemical properties and electrocatalytic activity of an unexpected nickel(II) Schiff base complex derived from bis(acetylacetonato)nickel(II), acetone and ethylenediamine",
        "abstract": "The synthesis, crystal structure and electrochemical properties of a Ni(II) Schiff base complex, [Ni(L)]PF (where L is 2,4,9,11,11-pentamethyl-2,3,4 triaza-1-one-4-amine) are reported herein. The complex has been characterized by its electrochemical behavior, X-ray crystallographic structural analysis, physio-chemical methods and spectroscopic techniques. Electrospray mass spectroscopic analysis gives a dominant ion peak with / = 296 which corresponds to the {[Ni(L)]PF–HPF} fragment. Cyclic voltammograms for [Ni(L)]PF, obtained in DMF (0.1 M BuNPF) at a glassy carbon electrode with a scan rate of 100 mV s, exhibit reversible ([Ni(L)]/[Ni(L)]) reduction and chemically irreversible ([Ni(L)]/[Ni(L)]→ electroactive product) oxidation processes at −2.05 and 0.62 V, respectively. The diffusion coefficient, calculated using the Randles–Sevcik relationship, is 9.7 × 10cms. Electrochemical studies reveal that the Ni reduced form of the complex is capable of catalyzing CO reduction at a potential that is thermodynamically more favorable than for the reduced [Ni(′-ethylenebis(acetylacetoneiminato)]complex. Spectroelectrochemical analyses following bulk electrolysis of [Ni(L)]PF under CO revealed the formation of oxalate and bicarbonate.",
        "keywords": [
            "Template Synthesis",
            "Schiff Base Complex",
            "Bu4N",
            "Mesityl Oxide",
            "NH4PF6"
        ],
        "authors": [
            {
                "name": "manawadevi y udugalaganehenege",
                "org": "university of peradeniya"
            },
            {
                "name": "yuping liu",
                "org": "monash university"
            },
            {
                "name": "craig m forsyth",
                "org": "monash university"
            },
            {
                "name": "alan m bond",
                "org": "monash university"
            },
            {
                "name": "jie zhang",
                "org": "monash university"
            }
        ],
        "venue": "Transition Metal Chemistry",
        "year": 2014
    },
    "mhNctpVM": {
        "id": "mhNctpVM",
        "title": "Cover Picture: Fourier‐Transformed Large‐Amplitude AC Voltammetric Study of Tetrathiafulvalene (TTF): Electrode Kinetics of the TTF0/TTF.+ and TTF.+/TTF2+ Processes (ChemElectroChem 1/2014)",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "alan m bond",
                "org": "monash university clayton campus"
            },
            {
                "name": "kiran bano",
                "org": "monash university clayton campus"
            },
            {
                "name": "shaimaa adeel",
                "org": "monash university clayton campus"
            },
            {
                "name": "lisandra l martin",
                "org": "monash university clayton campus"
            },
            {
                "name": "jie zhang",
                "org": "monash university clayton campus"
            }
        ],
        "venue": "",
        "year": 2014
    },
    "TV1lkBBm": {
        "id": "TV1lkBBm",
        "title": "Mediator Enhanced Water Oxidation Using Rb 4 [Ru II (bpy) 3 ] 5 [{Ru III 4 O 4 (OH) 2 (H 2 O) 4 }(γ-SiW 10 O 36 ) 2 ] Film Modified Electrodes",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "craig l hill",
                "org": ""
            },
            {
                "name": "yurii v geletii",
                "org": ""
            },
            {
                "name": "alan m bond",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "chongyong lee",
                "org": ""
            },
            {
                "name": "sixuan guo",
                "org": ""
            }
        ],
        "venue": "Inorganic Chemistry",
        "year": 2014
    },
    "0Fe5whrI": {
        "id": "0Fe5whrI",
        "title": "Probing Electrolyte Cation Effects on the Electron Transfer Kinetics of the [α-SiW 12 O 40 ] 4−/5− and [α-SiW 12 O 40 ] 5−/6− Processes using a Boron-Doped Diamond Electrode",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "jiezhen li",
                "org": ""
            },
            {
                "name": "alan m bond",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            }
        ],
        "venue": "Electrochimica Acta",
        "year": 2015
    },
    "flP2AY8I": {
        "id": "flP2AY8I",
        "title": "Performance comparison of the neon-like chromium soft x-ray lasing driven by a double laser pulse with different duration",
        "abstract": "",
        "keywords": [
            "chromium"
        ],
        "authors": [
            {
                "name": "Li Yu-tong",
                "org": ""
            },
            {
                "name": "Gu Yu-qiu",
                "org": ""
            },
            {
                "name": "Li Ying-jun",
                "org": ""
            },
            {
                "name": "Zhang Jie",
                "org": ""
            },
            {
                "name": "Chun-yu Shu-tai",
                "org": ""
            },
            {
                "name": "You Yong-lu",
                "org": ""
            },
            {
                "name": "He Shao-tang",
                "org": ""
            },
            {
                "name": "Huang Wen-zhong",
                "org": ""
            },
            {
                "name": "He Ying-ling",
                "org": ""
            },
            {
                "name": "Lu Li-zhu",
                "org": ""
            },
            {
                "name": "Yuan Xiao-dong",
                "org": ""
            },
            {
                "name": "Wei Xiao-feng",
                "org": ""
            },
            {
                "name": "Zhang Chuan-fei",
                "org": ""
            }
        ],
        "venue": "Acta Physica Sinica (overseas Edition)",
        "year": 1999
    },
    "4GwZU4ly": {
        "id": "4GwZU4ly",
        "title": "Diagnostics of Femtosecond Laser-Plasmas Using Fundamental and Second Harmonic Emission",
        "abstract": "",
        "keywords": [
            "second harmonic",
            "femtosecond laser"
        ],
        "authors": [
            {
                "name": "Zhao Li-Zeng",
                "org": ""
            },
            {
                "name": "Zhang Ping",
                "org": ""
            },
            {
                "name": "Feng Bao-Hua",
                "org": ""
            },
            {
                "name": "Wei Zhi-Yi",
                "org": ""
            },
            {
                "name": "Zhang Jie",
                "org": ""
            }
        ],
        "venue": "Chinese Physics Letters",
        "year": 2000
    },
    "CVIvspvc": {
        "id": "CVIvspvc",
        "title": "Effect of cluster coulomb fields on electron acceleration in laser-cluster interaction",
        "abstract": "Single particle simulations are used to investigate electron acceleration in the laser-cluster interaction, taking into account the Coulomb fields around individual clusters. These Coulomb fields are induced from the cluster cores with positive charge when electrons escape from the cluster cores through ponderomotive push from the laser field. These Coulomb fields enable some stripped electrons to be stochastically in phases with the laser fields so that they can gain net energy from the laser efficiently. In this heating mechanism, circularly polarized lasers, larger cluster size and higher cluster densities make the acceleration more efficient.",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Yu Cang",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Dong Quan-Li",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Wu Hui-Chun",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Sheng Zheng-Ming",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Wei Yu",
                "org": "Shanghai Institute of Optics and Fine Mechanics Chinese Academy of Sciences(Chinese Academy of Sciences,Chinese Acad of Sciences),Shanghai,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            }
        ],
        "venue": "Chinese Physics Letters",
        "year": 2004
    },
    "L1NyvH4c": {
        "id": "L1NyvH4c",
        "title": "Calculations of the energy levels and oscillator strengths of the Ne-like Fe Ion (Fe XVII)",
        "abstract": "Energy levels and oscillator strengths among the 27 fine-structure levels belonging to the (ls 2 2s 2 )2p 6 , 2p 5 3s, 2p 5 3p and 2p 5 3d configurations of the neon-like iron ion have been calculated using three atomic structure codes RCN/RCG, AUTOSTRUCTURE (AS) and GRASP. Relativistic corrections of the wave functions are taken into account in the RCN/RCG calculation. The results agree well with the available experimental and theoretical data. The accuracy of the three codes is analysed.",
        "keywords": [
            "atomic data",
            "energy levels",
            "fine structure",
            "atomic structure",
            "oscillations",
            "iron"
        ],
        "authors": [
            {
                "name": "Zhong Jia-yong",
                "org": "Institute of Physics, Chinese Academy of Sciences, Beijing 100080 China"
            },
            {
                "name": "Zhang Jie",
                "org": "Institute of Physics, Chinese Academy of Sciences, Beijing 100080 China"
            },
            {
                "name": "Zhao Gang",
                "org": "National Astronomical Observatories, Chinese Academy of Sciences, Beijing 100012 China"
            },
            {
                "name": "Lu Xin",
                "org": "Institute of Physics, Chinese Academy of Sciences, Beijing 100080 China"
            }
        ],
        "venue": "Chinese Astronomy and Astrophysics",
        "year": 2004
    },
    "3qd7SUwn": {
        "id": "3qd7SUwn",
        "title": "Chirping and spreading of ultrashort laser pulses in underdense plasmas",
        "abstract": "A linear theory on the propagation of ultrashort pulses including only a few cycles in underdense plasmas is presented. It is shown that the dispersion in plasmas causes severe distortions in the pulse shape, including pulse chirping and spreading. The analytical calculations coincide very well with those obtained by particle-in-cell (PIC) simulations. The upper limit of the peak amplitude of the pulses, above which the linear theory breaks down due to the setting in of nonlinear effects of both the relativistic electron-mass increase and ponderomotive force, is also examined by PIC simulations. At certain high amplitudes, it is found that the ultrashort laser pulses can propagate like solitons. © 2004 Chin. Phys. Soc. and IOP Publishing Ltd.",
        "keywords": [
            "Plasma",
            "Propagation",
            "Ultrashort laser pulse"
        ],
        "authors": [
            {
                "name": "Qiujü Zhang",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Sheng Zheng-Ming",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            }
        ],
        "venue": "Chinese Physics",
        "year": 2004
    },
    "jA9snpDD": {
        "id": "jA9snpDD",
        "title": "Characterization of density profile of cylindrical pulsed gas jets",
        "abstract": "We investigated the characteristics of argon and helium gas jets produced by a cylindrical nozzle under pressures from 1 to 6 MPa using a femtosecond laser interferometry. A radial parabolic distribution and an axial exponential distribution of the gas jet density profiles are identified. The results show that the density increases linearly with the backing pressure.",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Yu Quan-Zhi",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Li Yu-Tong",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Jun Zheng",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Li Han-Ming",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Peng Xiao-Yu",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Kun Li",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            }
        ],
        "venue": "Chinese Physics Letters",
        "year": 2004
    },
    "Q7qtAxjh": {
        "id": "Q7qtAxjh",
        "title": "Double Jet Emission of Hot Electrons from a Micro-droplet Spray",
        "abstract": "",
        "keywords": [
            "particle in cell"
        ],
        "authors": [
            {
                "name": "Peng Xiao-Yu",
                "org": ""
            },
            {
                "name": "Zhang Jie",
                "org": ""
            },
            {
                "name": "Liang Tian-Jiao",
                "org": ""
            },
            {
                "name": "Sheng Zheng-Ming",
                "org": ""
            },
            {
                "name": "Jin Zhan",
                "org": ""
            },
            {
                "name": "Li Yu-Tong",
                "org": ""
            },
            {
                "name": "Wang Zhao-Hua",
                "org": ""
            },
            {
                "name": "Yu Quan-Zhi",
                "org": ""
            },
            {
                "name": "Zheng Zhi-Yuan",
                "org": ""
            },
            {
                "name": "Liu Yun-Quan",
                "org": ""
            },
            {
                "name": "Wu Hui-Chun",
                "org": ""
            },
            {
                "name": "Hao Zuo-Qiang",
                "org": ""
            },
            {
                "name": "Yuan Xiao-Hui",
                "org": ""
            },
            {
                "name": "Wei Zhi-Yi",
                "org": ""
            }
        ],
        "venue": "Chinese Physics Letters",
        "year": 2004
    },
    "afB5OJHg": {
        "id": "afB5OJHg",
        "title": "Interaction of femtosecond laser pulses with metal photocathode",
        "abstract": "The features of interaction of femtosecond laser pulses with photocathode are studied theoretically in this paper. The surface temperature of the metal cathode film while femtosecond laser pulses irradiation is studied with two-temperature model. With a simple photoelectric model we obtain the optimum metal film thickness for the back-illuminated photocathode. The generated ultrashort photocurrent pulses are strongly dependent on the temperature of the electron gas and the lattice during the femtosecond laser pulse irradiation on the photocathode. © 2005 Chin. Phys. Soc. and IOP Publishing Ltd.",
        "keywords": [
            "Femtosecond laser",
            "Photocathode",
            "Ultrashort electron pulse time resolved electron"
        ],
        "authors": [
            {
                "name": "Liu Yun-Quan",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Liang Wen-Xi",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            }
        ],
        "venue": "Chinese Physics",
        "year": 2005
    },
    "LBgpGXAF": {
        "id": "LBgpGXAF",
        "title": "Grazing incidence pumping x-ray laser scheme with application of paraboloid mirrors",
        "abstract": "A grazing incidence pumping x-ray laser scheme using JIGUANG II is proposed. We investigate the characteristics of the focusing of parabolas, and obtain the optimal intensity distributions in the target surfaces with paraboloid mirrors of different parameters by the vectorial ray-tracing. Kinetic simulations are carried out. The results show that due to the enhancement of absorption by the selectable plasma region (gain region), saturated amplification of the x-ray laser can be achieved with 100 mJ energy in pre and pumping pulses, respectively, on 3 mm Ti targets. © 2005 Chinese Physical Society and IOP Publishing Ltd.",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Dong Quan-Li",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Fei Yan",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Zhong Jia-Yong",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Jing Zhao",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Sheng Zheng-Ming",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Li Han-Ming",
                "org": "China University of Mining Technology(China University of Mining and Technology,China Univ. of Mining and Technol.),Beijing,China"
            },
            {
                "name": "Li Ying-Jun",
                "org": "China University of Mining Technology(China University of Mining and Technology,China Univ. of Mining and Technol.),Beijing,China"
            }
        ],
        "venue": "Chinese Physics Letters",
        "year": 2005
    },
    "AyMNkZAP": {
        "id": "AyMNkZAP",
        "title": "Effects of Confined Laser Ablation on Laser Plasma Propulsion",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Zheng Zhi-Yuan",
                "org": ""
            },
            {
                "name": "Zhang Jie",
                "org": ""
            },
            {
                "name": "Lu Xin",
                "org": ""
            },
            {
                "name": "Hao Zuo-Qiang",
                "org": ""
            },
            {
                "name": "Xu Miao-Hua",
                "org": ""
            },
            {
                "name": "Wang Zhao-Hua",
                "org": ""
            },
            {
                "name": "Wei Zhi-Yi",
                "org": ""
            }
        ],
        "venue": "Chinese Physics Letters",
        "year": 2005
    },
    "XtQZZLBK": {
        "id": "XtQZZLBK",
        "title": "Coherence Measurement of White Light Emission from Femtosecond Laser Propagation in Air",
        "abstract": "",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Jin Zhan",
                "org": ""
            },
            {
                "name": "Zhang Jie",
                "org": ""
            },
            {
                "name": "Liu Yun-Quan",
                "org": ""
            },
            {
                "name": "Li Kun",
                "org": ""
            },
            {
                "name": "Yuan Xiao-Hui",
                "org": ""
            },
            {
                "name": "Hao Zuo-Qiang",
                "org": ""
            },
            {
                "name": "Zheng Jun",
                "org": ""
            },
            {
                "name": "Lu Xin",
                "org": ""
            },
            {
                "name": "Li Yu-Tong",
                "org": ""
            },
            {
                "name": "Wang Zhao-Hua",
                "org": ""
            },
            {
                "name": "Weijun Ling",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Wei Zhi-Yi",
                "org": ""
            }
        ],
        "venue": "Chinese Physics Letters",
        "year": 2005
    },
    "LXfg2wIc": {
        "id": "LXfg2wIc",
        "title": "Acoustic diagnostics of plasma channels induced by intense femtosecond laser pulses in air",
        "abstract": "Long plasma channels induced by femtosecond laser pulses in air are diagnosed using the sonographic method. By detecting the sound signals along the channels, the length and the electron density of the channels are measured. Refocusing is also observed at different laser energies and different focal lengths. We find that the sonographic method has manifest advantages compared to other techniques. © 2005 Chinese Physical Society and IOP Publishing Ltd.",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Hao Zuo-Qiang",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Jin Yu",
                "org": "Universite Claude Bernard Lyon 1(),Villeurbanne,France"
            },
            {
                "name": "Jie Zhang",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Li Yu-Tong",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Yuan Xiao-Hui",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Zheng Zhi-Yuan",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Peng Wang",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Wang Zhao-Hua",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Ling Wei-Jun",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Wei Zhi-Yi",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            }
        ],
        "venue": "Chinese Physics Letters",
        "year": 2005
    },
    "Fkvo1feC": {
        "id": "Fkvo1feC",
        "title": "Thomson Scattering Process in Laser-Produced Plasmas",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Yu Quan-Zhi",
                "org": ""
            },
            {
                "name": "Zhang Jie",
                "org": ""
            },
            {
                "name": "Li Yu-Tong",
                "org": ""
            },
            {
                "name": "Zheng Jun",
                "org": ""
            },
            {
                "name": "Yan Fei",
                "org": ""
            },
            {
                "name": "Lu Xin",
                "org": ""
            },
            {
                "name": "Wang Zhe-Bin",
                "org": ""
            },
            {
                "name": "Zheng Jian",
                "org": ""
            },
            {
                "name": "Yu Chang-Xuan",
                "org": ""
            },
            {
                "name": "Jiang Xiao-Hua",
                "org": ""
            },
            {
                "name": "Li Wen-Hong",
                "org": ""
            },
            {
                "name": "Liu Shen-Ye",
                "org": ""
            },
            {
                "name": "Zheng Zhi-Jian",
                "org": ""
            }
        ],
        "venue": "Chinese Physics Letters",
        "year": 2005
    },
    "h5143la4": {
        "id": "h5143la4",
        "title": "Effects of laser intensities and target shapes on attosecond pulse generation from irradiated solid surfaces",
        "abstract": "Single attosecond pulses can be generated when an intense laser pulse focused in a volume of a few cubic wavelengths (λ 3) is reflected from a solid plasma surface. With relati vistic two-dimensional particle-in-cell simulations, we investigate the effects of the incident laser intensity and the target surface profiles on attosecond pulse generation, usually the width of the reflected attosecond pulse decreases and its electromagnetic energy density increases with increasing laser intensity, while the energy conversion efficiency to the attoseond pulse decreases. By changing the target surface profile, such as using a convex surface or adding proper preplasma, one can further shorten the attosecond pulse duration and meanwhile increase its energy density. © 2005 Chinese Physical Society and IOP Publishing Ltd.",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Jun Zheng",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Sheng Zheng-Ming",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Min Chen",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Ma Yan-Yun",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            }
        ],
        "venue": "Chinese Physics Letters",
        "year": 2006
    },
    "tYu73KzH": {
        "id": "tYu73KzH",
        "title": "Generation of third harmonic emission in propagation of femtosecond laser pulses in air",
        "abstract": "The main characteristics of the third harmonic emission generated by femtosecond laser pulses propagating in air are investigated by numerically solving the coupled nonlinear Schrödinger equations. Strong third harmonic emission is observed with a maximum conversion efficiency as high as 0.43. The on-axis phase difference between fundamental beam and third harmonic is investigated. The result is in good agreement with the phase-locking mechanism. Dependence of the conversion of third harmonic emission on focusing conditions is also studied. The results are also compared with those of experiments. © 2006 Chin. Phys. Soc. and IOP Publishing Ltd.",
        "keywords": [
            "Plasma channel",
            "Third harmonic emission"
        ],
        "authors": [
            {
                "name": "Xi Ting-Ting",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Xin Lu",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Hao Zuo-Qiang",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Hui Yang",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Dong Quan-Li",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Wu Hui-Chun",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            }
        ],
        "venue": "Chinese Physics",
        "year": 2006
    },
    "sBy8EzwE": {
        "id": "sBy8EzwE",
        "title": "Successive particle acceleration by use of two tightly focused ultra-short intense laser pulses",
        "abstract": "",
        "keywords": [
            "particle acceleration"
        ],
        "authors": [
            {
                "name": "Chen Min",
                "org": ""
            },
            {
                "name": "Sheng Zheng-Ming",
                "org": ""
            },
            {
                "name": "Zhang Jie",
                "org": ""
            }
        ],
        "venue": "Chinese Physics",
        "year": 2006
    },
    "fnTabDK0": {
        "id": "fnTabDK0",
        "title": "The characteristics of confined ablation in laser propulsion",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Zheng Zhi-Yuan",
                "org": ""
            },
            {
                "name": "Zhang Jie",
                "org": ""
            },
            {
                "name": "Hao Zuo-Qiang",
                "org": ""
            },
            {
                "name": "Yuan Xiao-Hui",
                "org": ""
            },
            {
                "name": "Zhang Zhe",
                "org": ""
            },
            {
                "name": "Lu Xin",
                "org": ""
            },
            {
                "name": "Wang Zhao-Hua",
                "org": ""
            },
            {
                "name": "Wei Zhi-Yi",
                "org": ""
            }
        ],
        "venue": "Chinese Physics",
        "year": 2006
    },
    "NVxzVcLT": {
        "id": "NVxzVcLT",
        "title": "Femtosecond Laser-Induced Breakdown Spectroscopy for Detection of Trace Elements in Sophora Leaves",
        "abstract": "",
        "keywords": [
            "femtosecond laser",
            "trace element"
        ],
        "authors": [
            {
                "name": "myriam",
                "org": "chinese academy of sciences"
            },
            {
                "name": "bossu",
                "org": "chinese academy of sciences"
            },
            {
                "name": "郝作强",
                "org": "centre national de la recherche scientifique"
            },
            {
                "name": "matthieu",
                "org": "centre national de la recherche scientifique"
            },
            {
                "name": "baudelet",
                "org": "chinese academy of sciences"
            },
            {
                "name": "俞进",
                "org": "chinese academy of sciences"
            },
            {
                "name": "张喆",
                "org": "chinese academy of sciences"
            },
            {
                "name": "张杰",
                "org": "chinese academy of sciences"
            }
        ],
        "venue": "Chinese Physics Letters",
        "year": 2007
    },
    "iDS6mp6J": {
        "id": "iDS6mp6J",
        "title": "Evolution of shock waves formed by laser-induced breakdown in air",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Zhang Yi",
                "org": ""
            },
            {
                "name": "Li Yu-Tong",
                "org": ""
            },
            {
                "name": "Zheng Zhi-Yuan",
                "org": ""
            },
            {
                "name": "Liu Feng",
                "org": ""
            },
            {
                "name": "Zhong Jia-Yong",
                "org": ""
            },
            {
                "name": "Lin Xiao Xuan",
                "org": ""
            },
            {
                "name": "Liu Feng",
                "org": ""
            },
            {
                "name": "Lu Xin",
                "org": ""
            },
            {
                "name": "Zhang Jie",
                "org": ""
            }
        ],
        "venue": "Chinese Physics",
        "year": 2007
    },
    "5himIAhb": {
        "id": "5himIAhb",
        "title": "High Coupling Efficiency Generation in Water Confined Laser Plasma Propulsion",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Zheng Zhi-Yuan",
                "org": ""
            },
            {
                "name": "Zhang Yi",
                "org": ""
            },
            {
                "name": "Zhou Wei-Gong",
                "org": ""
            },
            {
                "name": "Lu Xin",
                "org": ""
            },
            {
                "name": "Li Yu-Tong",
                "org": ""
            },
            {
                "name": "Zhang Jie",
                "org": ""
            }
        ],
        "venue": "Chinese Physics Letters",
        "year": 2007
    },
    "thV6Y3Qd": {
        "id": "thV6Y3Qd",
        "title": "Potential fields of merging and splitting filaments in air",
        "abstract": "",
        "keywords": [
            "ray tracing"
        ],
        "authors": [
            {
                "name": "Ma Yuan-Yuan",
                "org": ""
            },
            {
                "name": "Lu Xin",
                "org": ""
            },
            {
                "name": "Xi Ting-Ting",
                "org": ""
            },
            {
                "name": "Hao Zuo-Qiang",
                "org": ""
            },
            {
                "name": "Gong Qi-Huang",
                "org": ""
            },
            {
                "name": "Zhang Jie",
                "org": ""
            }
        ],
        "venue": "Chinese Physics",
        "year": 2007
    },
    "ZbQ7GiFT": {
        "id": "ZbQ7GiFT",
        "title": "Influence of initial pulse chirp on rainbow-like supercontinuum generation from filamentation in air",
        "abstract": "Supercontinuum (SC) generation from laser filamentation in air is found to depend strongly on the pulse duration. Rainbow-like SC generation is observed only for a pulse of appropriate negative chirp that agrees with the predictions put forward by Golubtsov et al. [Quantum Electron. 33 (2003) 525]. The conversion efficiency of an 800-nm laser light to rainbow-like SC is found to be the highest for 257 fs pulses with an initial negative chirp. A larger chirp will lead to filamentation surviving at longer distance. © 2008 Chinese Physical Society and IOP Publishing Ltd.",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Hao Zuo-Qiang",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Zhe Zhang",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Xin Lu",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Zhan Jin",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Zhong Jia-Yong",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Liu Yun-Quan",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Wang Zhao-Hua",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            }
        ],
        "venue": "Chinese Physics Letters",
        "year": 2008
    },
    "1BVleM8q": {
        "id": "1BVleM8q",
        "title": "Ultrafast Electron Diffraction with Spatiotemporal Resolution of Atomic Motion",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "clinite rick",
                "org": ""
            },
            {
                "name": "zhang zhongchao",
                "org": ""
            },
            {
                "name": "nie shouhua",
                "org": ""
            },
            {
                "name": "wang xuan",
                "org": ""
            },
            {
                "name": "zhu pengfei",
                "org": ""
            },
            {
                "name": "liang wenxi",
                "org": ""
            },
            {
                "name": "cao jianming",
                "org": ""
            },
            {
                "name": "sheng zhengming",
                "org": ""
            },
            {
                "name": "zhang jie",
                "org": ""
            }
        ],
        "venue": "Chinese Physics Letters",
        "year": 2009
    },
    "UKILf8ZT": {
        "id": "UKILf8ZT",
        "title": "Ultrafast Electron Diffraction with Spatiotemporal Resolution of Atomic Motion",
        "abstract": "",
        "keywords": [
            "structural dynamics",
            "thin film",
            "electron diffraction",
            "real time"
        ],
        "authors": [
            {
                "name": "Liang Wen-Xi",
                "org": ""
            },
            {
                "name": "Zhu Peng-Fei",
                "org": ""
            },
            {
                "name": "Wang Xuan",
                "org": ""
            },
            {
                "name": "Nie Shou-Hua",
                "org": ""
            },
            {
                "name": "Zhang Zhong-Chao",
                "org": ""
            },
            {
                "name": "Clinite Rick",
                "org": ""
            },
            {
                "name": "Cao Jian-Ming",
                "org": ""
            },
            {
                "name": "Sheng Zheng-Ming",
                "org": ""
            },
            {
                "name": "Zhang Jie",
                "org": ""
            }
        ],
        "venue": "Chinese Physics Letters",
        "year": 2009
    },
    "Ipudvgg5": {
        "id": "Ipudvgg5",
        "title": "Demonstration of Mo Soft X-Ray Lasers with a Grazing Incidence Pumping Scheme in the XL-II Facility",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Dong Quan-Li",
                "org": ""
            },
            {
                "name": "Wang Shou-Jun",
                "org": ""
            },
            {
                "name": "Wang Zhao-Hua",
                "org": ""
            },
            {
                "name": "Zhao Jing",
                "org": ""
            },
            {
                "name": "Wei Zhi-Yi",
                "org": ""
            },
            {
                "name": "Zhang Jie",
                "org": ""
            }
        ],
        "venue": "Chinese Physics Letters",
        "year": 2009
    },
    "tKeXw0xY": {
        "id": "tKeXw0xY",
        "title": "Influence of Initial Amplitude Perturbations on Filament Length of Pre-focused Femtosecond Laser Pulses",
        "abstract": "Influence of random initial amplitude perturbations on the filamentation of prefocused femtosecond laser pulses is numerically studied.Simulations are performed for the filamentation of laser pulses with different modulation degrees and initial geometric focusings.The transverse waist of the laser beam is 5 mm.The behavior of the filament is strongly affected by the initial non-uniformity of the laser pulse envelope for a short initial focal length(f=1 m).In this case,the filament and plasma channel can survive for a longer distance with a small initial amplitude perturbation.For a laser pulse focused by a lens with a long focal length(f=4 m),decrease in the initial perturbation does not contribute to the length of the filament and the plasma channel.",
        "keywords": [
            "self-focusing",
            "perturbation",
            "filamentation",
            "femtosecond laser"
        ],
        "authors": [
            {
                "name": "Ma Yuanyuan",
                "org": ""
            },
            {
                "name": "Lu Xin",
                "org": ""
            },
            {
                "name": "Xi Tingting",
                "org": ""
            },
            {
                "name": "Gong Qihuang",
                "org": ""
            },
            {
                "name": "Zhang Jie",
                "org": ""
            }
        ],
        "venue": "Plasma Science & Technology",
        "year": 2009
    },
    "jot6z1kC": {
        "id": "jot6z1kC",
        "title": "Ray-tracing simulation on filamentation of prefocused and freely propagated laser pulses in air",
        "abstract": "The filamentation mechanisms of prefocused and freely propagated femtosecond laser pulses are compared using the ray-tracing method. The dynamic spatial replenishment mechanism takes place in the filaments with high electron density, which is generally formed by prefocused laser pulses. The mechanism of long-range filamentation over 100 m distance is analyzed to be the spatiotemporal moving focus. © 2009 Chinese Physical Society and IOP Publishing Ltd.",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Ma Yuan-Yuan",
                "org": "Peking University(Peking University),Beijing,China"
            },
            {
                "name": "Xin Lu",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Xi Ting-Ting",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Gong Qi-Huang",
                "org": "Peking University(Peking University),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Peking University(Peking University),Beijing,China"
            }
        ],
        "venue": "Chinese Physics Letters",
        "year": 2009
    },
    "C5ZKtHkG": {
        "id": "C5ZKtHkG",
        "title": "Analysis on variations of ecological water demand in growth period in Heihe valley",
        "abstract": "Based on the biological characters of different vegetations,the ecological water demand of crops in every 10 days from March to October was estimated,and the variations of the planting area of crops,the irrigation area and the water demand of croplands and natural oasis in recent 20 years were analyzed,by using the meteorological data of Zhangye and Ejinaqi observatories.The results showed that the area of cash crops was increased while that of grain crops was dropped by 26.6%,as a result of industry structure adjustment in the oasis region.There were differences of the apex of water demand among wheat,corn and forests,i.e.,their apex time was the middle ten days of June,the middle ten days of August and the last ten days of August,and the apex quantity of was 6.14mm,8.6 mm and 8.0 mm respectively.The apex time and amount of regional average ecological water demand in the artificial oasis was the middle ten days of June and 6.37 mm/d,and that in the natural oasis was the last ten days of August and 6.06 mm/d.As for the whole Heihe valley,the apex time of water demand was the middle and last ten days of June,and the apex amount was 6.03 mm/d.The time discrepancy of water demand between the artificial oasis in the middle reaches and the natural oasis in the lower reaches of Heihe valley provides the basis for reasonable distribution of water resource.",
        "keywords": [
            "artificial oasis",
            "growth period",
            "Heihe valley",
            "ecological water demand",
            "natural oasis"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Key Laboratory of Arid Climatic Changing and Reducing Disaster of Gansu Province"
            },
            {
                "name": "LI Dong-liang",
                "org": "Cold and Arid Regions Environmental and Engineering Research Institute,CAS,Lanzhou ,China"
            }
        ],
        "venue": "Agricultural Research in the Arid Areas",
        "year": 2006
    },
    "vpnqzPZi": {
        "id": "vpnqzPZi",
        "title": "Analysis of Echo Character of Doppler Radar for a Severe Convection in the Mid-Part of Gansu Province",
        "abstract": "Combining CINRAD/CC Doppler radar data with some routine observation data including surface and aerological chart,Yuzhong RW station information,ground-based automatism stations observations and DEM data in the distance of 150 km,the mesoscale weather processes on 18 August 2004 have been analyzed.The results show that the severe convective processes happened under upper level cold and lower level warm advection circumstance and terrain effect belonging to different advection type hailstorm.The herringbone and bow echo shape of reflectivity factor have occurred,adverse wing region and microcyclone appear of average radial velocity,and there are convergence on lower level and divergence on upper level characters in the regions of hail formed.There are strongly circumgyrating and rising air current in the PPI.The strong echo region may be some relationships with convergence region,adverse wind region,microcyclone,VIL region,at the same time,VIL product is well used for region prediction of hail happened.",
        "keywords": [
            "CINRAD/CC",
            "Adverse wind region",
            "VIL",
            "Mesoscyclone",
            "Convergence(divergence) region",
            "DEM"
        ],
        "authors": [
            {
                "name": "FU Shuang-xi",
                "org": "Gansu Province Artificial Modification Office,Lanzhou ,China"
            },
            {
                "name": "WANG Zhi-jun",
                "org": "Cold and Arid Region Institute Environmental andEngineering,Chinese Academy of Sciences,Lanzhou ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Lanzhou Institute of Arid Meteorology,China Meteorological Administration,Lanzhou ,China"
            },
            {
                "name": "CHEN Qian",
                "org": "Gansu Province Artificial Modification Office,Lanzhou ,China"
            }
        ],
        "venue": "Plateau Meteorology",
        "year": 2006
    },
    "EkyuQdqS": {
        "id": "EkyuQdqS",
        "title": "Grass NPP Estimation by Remote Sensing and Its Feasibility in Desert Grassland",
        "abstract": "By the estimation method of the efficiency for solar energy utilization,the monthly and annual grass net primary productivity(NPP) of the desert area in Anxi County of Gansu lying in desert oasis area of Northwest China are estimated with EOS/MODIS data collected in May～October 2005 and the temporal and spatial distributions of the net production rates of the different grasses are analyzed in combination with field observation.It is shown that in the desert area of Anxi County the grass NPP appeared the highest in June and July 2005 during growth season and lower in the other months during the growth season,and May～June are the period when the leaf area index greatly varies and the NPP significantly varies;the desert grasses greatly differ in solar energy utilization and carbon dioxide assimilation,and Nitraria tangutorum,Lycium ruthenicum and Reaumuria soongorica are the grasses with high NPP;In the desert area spatial distribution of the annual NPP varies greatly and the NPP in the grazing-prohibited area is higher than that in the grazing area,and this agrees with the result in the field observation.The average NPP error is 12.6% in the estimation.",
        "keywords": [
            "grass type",
            "desert grass in Northwest China",
            "temporal and spatial distribution",
            "remote sensing estimation",
            "NPP"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": " Key Laboratory of Arid Climatic Changing and Reducing Disaster of Gansu Province and CMA"
            },
            {
                "name": "ZHANG Qiang",
                "org": " Key Laboratory of Arid Climatic Changing and Reducing Disaster of Gansu Province and CMA"
            },
            {
                "name": "GUO Ni",
                "org": " Key Laboratory of Arid Climatic Changing and Reducing Disaster of Gansu Province and CMA"
            },
            {
                "name": "SUN Bing",
                "org": " Gansu Stock Bureau,Lanzhou ,China"
            }
        ],
        "venue": "Acta Botanica Boreali-Occidentalia Sinica",
        "year": 2006
    },
    "39qQWp6Q": {
        "id": "39qQWp6Q",
        "title": "Remote Sensing Retrieval and Analysis of Optical Character of Cloud in Qilian Mountains",
        "abstract": "By using MODIS data from Terra and Aqua satellite,6 hours precipitation data of 18 cases from 2002 to 2005,applying 6S Model and Mie Model,some parameters,including optical thickness of cloud,efficient radius of cloud particle and content of liquid water,are retrieved.Their special distributions are also analyzed by combining with GIS software.Then,the relation of all those parameters and 6 hours precipitation are analyzed.The results show that there is a striking dissimilarity in special distribution of the optics thickness and efficient radius of cloud particle,which is influenced by terrain,with a maximum on the south slopes lower than 4 300 m of the mountains,a region with rich resources of cloud water.There are positive correlation between precipitation and the three parameters.Precipitation probability is large when optical thickness changes from 8 to 20,efficient radius of cloud particle changes from 6 to 12 μm and content of liquid water is more than 0.04 g5m~(-3).Content of liquid water higher than 0.15 g5m~(-3) at 4 300 m a.s.l.shows that there is a large potential to exploit cloud water in the Qilian Mountains.",
        "keywords": [
            "Qilian Mountains",
            "efficient radius of cloud particle",
            "content of liquid water",
            "EOS-MODIS",
            "optical thickness of cloud"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Key Laboratory of Arid Climatic Changing and Reducing Disaster of Gansu Province,Key Laboratory of Arid Climate Change and Disaster Reduction of CMA Institute of Arid Meteorology,China Meteorological Administration,Lanzhou Gansu ,China"
            },
            {
                "name": "ZHANG Qiang",
                "org": "Key Laboratory of Arid Climatic Changing and Reducing Disaster of Gansu Province,Key Laboratory of Arid Climate Change and Disaster Reduction of CMA Institute of Arid Meteorology,China Meteorological Administration,Lanzhou Gansu ,China"
            },
            {
                "name": "TIAN Wen-shou",
                "org": "Institute of Atmospheres Science,Lanzhou University,Lanzhou Gansu ,China"
            },
            {
                "name": "HE Jin-mei",
                "org": "Lanzhou Central Meteorological Observatory,Lanzhozu Gansu ,China"
            }
        ],
        "venue": "Journal of Glaciology and Geocryology",
        "year": 2006
    },
    "gu8QCM6Y": {
        "id": "gu8QCM6Y",
        "title": "Analyses of the Influence of Sand Dust Aerosol on Vegetation Remote Sensing in Northwest China",
        "abstract": "Some representative MODIS data are picked up and atmosphere correction is done by using 6S model.The influence of sand dust aerosol on VI in Northwest China is analysed.The result showed that sand dust aerosol is of some radiation characteristic,which lead to reflectivityρ1,ρ2,ρ3 increased,and the values of NDVI and ARVI are decreased if the atmosthere correction is did.The value of NDVI is minished by influencing of sand dust,and the maximum value is 0.246,the value of ARVI is minished by influencing of sand dust,and the maximum value is 0.231.By using the some data in clear sky,a linearity relation between ARVI and NDVI is established,this relation is used well in sandy day.",
        "keywords": [
            "6S model",
            "Atmosphere correction",
            "Northwest China",
            "Vegetation index",
            "Sand dust aerosol"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Key Laboratories of Arid Climatic Change and Reducing Disaster of Gansu Province and China Meteorological Administration,Lanzhou Institute of Arid Meteorology,China Meteorological Administration,Lanzhou ,China"
            },
            {
                "name": "GUO Ni",
                "org": "Key Laboratories of Arid Climatic Change and Reducing Disaster of Gansu Province and China Meteorological Administration,Lanzhou Institute of Arid Meteorology,China Meteorological Administration,Lanzhou ,China"
            },
            {
                "name": "HAO Zhi-yi",
                "org": "Section Operation,Gansu Meteorological Bureau,Lanzhou ,China"
            }
        ],
        "venue": "Plateau Meteorology",
        "year": 2006
    },
    "b29yfoVM": {
        "id": "b29yfoVM",
        "title": "The Study of Cloud Detection with Multi-Channel Data of Satellite",
        "abstract": "Cloud detection is,by using various algorithms,to determine whether a pixel(or small area that is viewed by the satellite at a given time) is cloudy,clear or undecided.It plays an important role in analyzing satellite images,since the cloud influences should be removed from the images in the earth study,and then the authors can pick up clouds and to know where and how much the clouds are.Moreover,it is useful to determine the possible effects of clouds on climate in remote and mountain regions.In order to do this,the purpose of this study is to systematically present several algorithms of cloud-detection;and to find a more accurate algorithm that is helpful to understand the condition of cloud water over Qilian Mountains.In this study,the cloud detection algorithms established with the multi-channel data of GMS-5 are introduced.There are four channels including two infrared split channels,visual channel and water vapor channel in GMS-5.About 3000 digital-data samples are taken out from the satellite images.The multi-channel cloud detection contains five kinds of samples including cloud,land,water,desert and snow-pack in four satellite channels.The study period is from July 1 to September 30,2002 and the study area is from 8.65° N to 59.65° N and from 73.22° E to 134.42° E covering the whole China(1024×1024 pixels).Based on the theory of remote sensing and the statistical characteristics of samples,cloud detection algorithms are established.In the first test,the algorithm is commonly used through utilizing thresholds of the GMS-5 infrared and visual channels.The threshold values are built only from the two channels and to obtain results that contain most pixels of cloud,but the threshold values are changing with the season or solar altitude.When comparing the result images with the visual images,it shows that the detected pixels decrease in higher latitudes and increase in lower latitudes.The second algorithm is designed by using the difference of gray levels between two GMS-5 infrared channels,and the threshold of infrared 1 and water vapor channel.In the detected images,the second algorithm is also affected by latitude.The detected cloud pixels are less in higher latitudes,and are more in lower latitudes,which is reverse from the first algorithm.Although it has only been tested in the daytime,because the second algorithm derives little effect from visual channel,it should perform quite well in any time as well.Moreover,there are four stable thresholds in the second algorithm.The third algorithm is more accurate,which is based on the two aforesaid algorithms.Because the third algorithm inherits the strongpoint of the two aforesaid algorithms,its results show that it can offer improved technique of the cloud detection applied to GMS-5 imagery.Investigating the quality of the three algorithms,it is showed that the multi-channel incorporate method of cloud detection achieves a good agreement with the visible picture.However,it is difficult for the three algorithms to distinguish clouds from snow packs in GMS-5 images.",
        "keywords": [
            "cleaning cloud",
            "gray levels",
            "multi-channel",
            "satellite image",
            "threshold"
        ],
        "authors": [
            {
                "name": "MA Fang",
                "org": " Chinese Academy of Meteorological Sciences,Beijing 2 Key Laboratory of Arid Climatic Changing and Reducing Disaster of Gansu Province,Institute of Arid Meteorology,China Meteorological Administration,Lanzhou ;%%#"
            },
            {
                "name": "ZHANG Qiang",
                "org": "%%#"
            },
            {
                "name": "GUO Ni",
                "org": "%%#"
            },
            {
                "name": "ZHANG Jie",
                "org": "%%#"
            }
        ],
        "venue": "Chinese Journal of Atmospheric Sciences",
        "year": 2007
    },
    "m0yQhxHu": {
        "id": "m0yQhxHu",
        "title": "The Influential Factors of the Arid and Semi-Arid Area on the Ecosystem in the Northwestern China",
        "abstract": "By analyzing the change laws of the spatial-temporal distribution of precipitation,the desert borderlines and the ecotone between agriculture and pasture,it is suggested that the arid and semi-arid is the main climatic characteristic in northwest China.The ecosystem is very sensitive and weak.The structure of agriculture and pasture established aiming at keeping the people having adequate food and clothing and driven by economic interests is the main cause of worsening ecosystem and environment.",
        "keywords": [
            "precipitation",
            "northwestern China",
            "ecosystem",
            "plant structure"
        ],
        "authors": [
            {
                "name": "Kang Fengqin",
                "org": "Key Laboratory of Arid Climate Change and Reducing Disaster of Gansu Province,Key Open Laboratory of Arid Climate Change and Reducing Disaster,China Meteorology Administrator,Lanzhou Institute of Arid Meteorology,China Meteorology Administrator,Lanzhou ,China"
            },
            {
                "name": "Zhang Jie",
                "org": "Key Laboratory of Arid Climate Change and Reducing Disaster of Gansu Province,Key Open Laboratory of Arid Climate Change and Reducing Disaster,China Meteorology Administrator,Lanzhou Institute of Arid Meteorology,China Meteorology Administrator,Lanzhou ,China"
            },
            {
                "name": "Wang Jing",
                "org": "Key Laboratory of Arid Climate Change and Reducing Disaster of Gansu Province,Key Open Laboratory of Arid Climate Change and Reducing Disaster,China Meteorology Administrator,Lanzhou Institute of Arid Meteorology,China Meteorology Administrator,Lanzhou ,China"
            }
        ],
        "venue": "Journal of Catastrophology",
        "year": 2007
    },
    "XFegHr9D": {
        "id": "XFegHr9D",
        "title": "Development of Distribution Model of Precipitation in Rainy Season in the East Qinghai-Tibetan Plateau",
        "abstract": "Based on the high-resolution graphics-3\" digital model and the precipitation data observed by 102 meteorological stations in the east Qinghai-Tibetan Plateau during the period from May to September,in this study a correlation model between the seasonal(rainy season) and annual precipitation and the 6 geographical and topographical factors(including the longitude,latitude,height above sea level,gradient,aspect and topographical opening degree) in the east Qinghai-Tibetan Plateau during the period from 1961 to 2000 is developed using the multivariate regression,and the spatial distribution of precipitation in the east Qinghai-Tibetan Plateau is estimated.The results reveal that there is a prominent correlation between the precipitation and the geographical and topographical factors,the relative error is within 20%,the average relative error is within 4.4%,and all the correlation coefficients estimated with the model are tested with confidence of 0.95.The effects of the geographical factors on the average precipitation in rainy season and annual precipitation are relatively stable,and the normalized simulation coefficients are within ±1,that means the high-resolution graphics-3\" digital model can be used to significantly increase the simulation precision of geographical factors,such as the gradient,aspect and topographical opening,thus the simulation precision of spatial distribution of precipitation can also be increased,which is very important for quantitatively analyzing and estimating precipitation in the plateau where there are not enough meteorological stations and the terrain is complicated.",
        "keywords": [
            "digital altitude 3\"",
            "east Qinghai-Tibetan Plateau",
            "geographical factor",
            "topographical factor",
            "distribution of precipitation in rainy season",
            "estimation model."
        ],
        "authors": [
            {
                "name": "LUO Qi",
                "org": "Gansu Province Center of Meteorological Information and Equipment Supply,Lanzhou ,China"
            },
            {
                "name": "LI Dong-liang",
                "org": "Cold and Arid Regions Environmental and Engineering Research Institute,Chinese Academy of Sciences,Lanzhou ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Lanzhou Institute of Arid Meteorology,China Meteorological Administration,Lanzhou ,China"
            }
        ],
        "venue": "Arid Zone Research",
        "year": 2007
    },
    "bpsjPjDb": {
        "id": "bpsjPjDb",
        "title": "Estimation and analysis of grass biomass in desert by remote sensing",
        "abstract": "Net Primary Productivity in desert-oasis region in Northwest China is estimated combined the model of light energy utilization with EOS/MODIS data from May to Oct.. On the basis of NPP and observed value of aboveground biomass, biomass model is also built, then, temporal and spatial distribution of biomass and NPP are analyzed. The results show that NPP is larger in June and July than other growth periods, grass LAI and NPP change rapidly from May to June. Estimated error of 44 cases by the biomass model is less than 20%, which show that the biomass model is very good , the model can describe growing status. Photosynthesis and respiration are different because of different type grass , three types grass are more adaptive to desert environment and the biomass are also big, the grass types include Alhagi sparsifolia, Lycium ruthenicum and Reaumuria songarica. The grass biomass is influenced by many factors such as grass type, total cover and plant height et al.",
        "keywords": [
            "grass type",
            "desert grass in Northwest China",
            "temporal and spatial distribution",
            "estimation by remote sensing",
            "NPP",
            "aboveground biomass"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": " Key Laboratory of Arid Climatic Changing and Reducing Disaster of Gansu Province,Key open Laboratory of Arid Climatic Changing and Disaster Reduction of CMA. Institute of Arid Meteorology, China Meteorological Administration, Lanzhou , China"
            },
            {
                "name": "ZHANG Qiang",
                "org": " Key Laboratory of Arid Climatic Changing and Reducing Disaster of Gansu Province,Key open Laboratory of Arid Climatic Changing and Disaster Reduction of CMA. Institute of Arid Meteorology, China Meteorological Administration, Lanzhou , China"
            },
            {
                "name": "HE Jin-Mei",
                "org": " Lanzhou Observatory Central,Lanzhou ,China"
            },
            {
                "name": "SUN Bing",
                "org": " Gansu Stock Bureau ,Lanzhou , China"
            }
        ],
        "venue": "Acta Ecologica Sinica",
        "year": 2007
    },
    "qNIgUMbb": {
        "id": "qNIgUMbb",
        "title": "RESEARCH ON ATMOSPHERIC WATER-VAPOR DISTRIBUTION OVER QILIANSHAN MOUNTAINS",
        "abstract": "Based on the remote sensing data,the radiosonde data and the precipitation data observed by weather stations,distributions of water-vapor in air and cloud motion winds in the Qilianshan Mountains are analyzed.Moreover,on the basis of water-vapor and cloud motion wind analyses,relations of atmospheric water-vapor distribution with precipitation,atmospheric circulation and terrain are investigated.The results show that distributions of atmospheric water-vapor and precipitation in Qilianshan Mountains are affected by the westerly belt,the southerly monsoon(the South Asian monsoon and Tableland monsoon) and the East Asian monsoon.In the northwest region of the Qilianshan Mountains,water-vapor and precipitation are entirely affected by the westerly belt flow,and there is no other direction water-vapor transport except westerly water-vapor flux,so,the northwest region is regarded as the westerly belt region.In the south and middle region of the Mountains,water-vapor is mainly controlled by the southerly monsoon,37.7% of the total water-vapor is from the south,especially in summer,the southerly water-vapor flux accounts for 55.9% of the total,and furthermore the water-vapor content in the southerly flow is more than that in the westerly flow.The southerly monsoon water-vapor is influenced by the South Asian monsoon from the Indian Ocean and the tableland monsoon in the Qinghai-Tibet plateau,so,the south and middle region is called the southerly monsoon region.But in the northeast region of the Mountains,the East Asian monsoon is the main climate system affecting the water-vapor in this region,except west and northwest water-vapor fluxes,there are a lot of easterly water-vapor fluxes in summer.The frequency of easterly cloud-motion winds in summer half year accounts for 27.1% of the total,though the frequency is not too high,it is the main water-vapor source of summer precipitation in this region,therefore,the northeast region is a marginal region of East Asian monsoon.On the other hand,atmospheric water-vapor,precipitation and the convert rate of water-vapor into precipitation are close related with altitude and circulation systems.Generally,there is a peak value of water-vapor content at the altitude from 3500 m to 4500 m on the windward slope,but on the leeward slope,water-vapor monotunically decreases with reduce in altitude except for that in the East Asia monsoon region.Water-vapor on the leeward slope is much less than that on the windward slope,and the maximal difference in water-vapor content between both sides may reaches about 4.49 kg/m2.Whether the value of water-vapor content,precipitation or the convert rate of water-vapor into precipitation all reach their maximals in the East Asian monsoon region,and correspondingly the peak value of water-vapor on the windward slope is also larger and occurs at a lower altitude in comparison with other two regions.",
        "keywords": [
            "Qilian Mountains",
            "Satellite remote sensing data",
            "Atmospheric water-vapor",
            "Cloud-motion wind",
            "Atmospheric circulation."
        ],
        "authors": [
            {
                "name": "Zhang Qiang",
                "org": " Institute of Arid Meteorology,CMA,Lanzhou  Key Laboratory of Arid Climatic Changing and Reducing Disaster of Gansu Province,Lanzhou  Key Open Laboratory of Arid Climatic Changing and Disaster Reduction of CMA,Lanzhou "
            },
            {
                "name": "Zhang Jie",
                "org": " Institute of Arid Meteorology,CMA,Lanzhou  Key Laboratory of Arid Climatic Changing and Reducing Disaster of Gansu Province,Lanzhou  Key Open Laboratory of Arid Climatic Changing and Disaster Reduction of CMA,Lanzhou "
            },
            {
                "name": "Di Xiaohong",
                "org": " Lanzhou Observatory Central,Lanzhou "
            }
        ],
        "venue": "Acta Meteorologica Sinica",
        "year": 2007
    },
    "eDLu1BQh": {
        "id": "eDLu1BQh",
        "title": "Influence of terrain on precipitation distribution in Qingzang tableland in wet and dry years",
        "abstract": "Combined 3″ digital elevate model (DEM) data with the precipitations of 102 stations in the east of Qingzang tableland from May to Nov., based on the relation of precipitation distribution with altitude, the stations are divide into three parts, and the relationships between the rainy season precipitations of 40 years (1961-2000) and six factors longitude, latitude, altitude, gradient, direction of slope and opening are established by using the stepwise regress method. Based on the relationships (models), the change laws of every factor's coefficiency in wet and dry years are analyzed. The result show that the relativity of the models are remarkable: the relative error is less than 20%, average value of relative error 4.4%, and the relativity passes by 0.05 test. The precipitation distribution in wet and dry years is influenced by altitude and opening in the first region with less than 1400 m altitude; as for the second region with more than 1400 m altitude and less than 3600 m altitude, the precipitation is influenced by altitude, longitude and opening, as for the third region with more than 3600 m altitude, the precipitation is influenced by opening and gradient. When the tableland monsoon becomes strong, the influence of opening and longitude on precipitation is more remarkable, and the influence of gradient and altitude is weaker, therefore, the regional character of water-vapor distribution is notable, the difference in the east and the west become more obvious, so did the precipitation. Therefore, the geographical and topographical factors influence upright motion of atmosphere, which results in difference of precipitation distribution.",
        "keywords": [
            "3″ DEM data",
            "East of the Qingzang tableland",
            "Geographical factors",
            "Precipitation distribution in rainy season",
            "Topographical factors",
            "Wet and dry years"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "China Meteorological Administration(China Meteorological Administration,CMA),Beijing,China"
            },
            {
                "name": "LI Dong-liang",
                "org": "Cold and Arid Regions Environmental and Engineering Research Institute Chinese Academy of Sciences(Chinese Academy of Sciences,CAS),Lanzhou,China"
            },
            {
                "name": "HE Jin-mei",
                "org": "Lanzhou Central Meteorological Observatory(Lanzhou Central Meteorological Observatory),Lanzhou,China"
            },
            {
                "name": "WANG Xiao-yan",
                "org": "Gansu Meteorological Bureau(Gansu Meteorological Training Centre,Gansu Meteorological Bureau),Lanzhou,China"
            }
        ],
        "venue": "Shuikexue Jinzhan/Advances in Water Science",
        "year": 2007
    },
    "U2epE62U": {
        "id": "U2epE62U",
        "title": "Contrast and Calibration of Remote Sensing Production NDVI of NOAA/AVHRR and EOS/MODIS",
        "abstract": "Using the MODIS data of Terra and Aqua satellites,AVHRR data of NOAA-16 and NOAA-17,data calibration are done in allusion to influence of zenith and azimuth angle of sun and sensors,scatter of aerosol particle,and attenuation of sensor on NOAA satellites.By calibration,some NDVI values are gained,NDVI of Terra and NOAA-17,NDVI of Aqua and NOAA-16 are analyzed,the relations of NDVI with spectral response function are also analyzed.The results show that NDVI from Terra and Aqua change with observing angles,average NDVI is a perfect composite arithmetic,which represent NDVI within ±30° angle.Angle calibration of NDVI is done again.NDVI from NOAA-16 and NOAA-17 are less than it from MODIS,referred to MODIS NDVI,the NDVI from NOAA is normalized according to spectral response functions,normalized NDVI is very closed to NDVI from MODIS,which means that it is a perfect method to continue NDVI production.",
        "keywords": [
            "Spectral response function",
            "Calibration",
            "Northwest China",
            "NOAA/AVHRR and EOS/MODIS data",
            "NDVI"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Key Laboratory of Arid Climatic Changing and Reducing Disaster of Gansu Province,Key Openning Laboratory of Arid Climatic Change and Disaster Reduction,China Meteorological Administration,Lanzhou Institute of Arid Meteorology,China Meteorological Administration,Lanzhou ,China"
            },
            {
                "name": "GUO Ni",
                "org": "Key Laboratory of Arid Climatic Changing and Reducing Disaster of Gansu Province,Key Openning Laboratory of Arid Climatic Change and Disaster Reduction,China Meteorological Administration,Lanzhou Institute of Arid Meteorology,China Meteorological Administration,Lanzhou ,China"
            },
            {
                "name": "WANG Jie-min",
                "org": "Cold and Arid Regions Environmental and Engineering Research Institute,Chinese Academy of Sciences,Lanzhou ,China"
            }
        ],
        "venue": "Plateau Meteorology",
        "year": 2007
    },
    "LccMFNhG": {
        "id": "LccMFNhG",
        "title": "The Operation Synthetical System for Hail Monitoring,Warning and Hail Suppression Command in Northwest China",
        "abstract": "The operation synthetical system for hail monitoring,warning and hail suppression command in Northwest China consists of four sub-systems,including the hail disaster database,the hail monitoring system,the hail warning system and the hail suppression commanding system.Based on the present research results,the system has used the new data from Doppler weather radar,satellite remote sensing,lightning monitoring and so on to build a powerful,convenient and open command platform for hail monitoring,warning and suppressing by the primary means of the computer network and software technology.The system is valuable in the operation application.And this paper has highlighted the function and the design of the system.",
        "keywords": [
            "hail",
            "monitoring",
            "command",
            "Northwest China",
            "hail suppression",
            "warning"
        ],
        "authors": [
            {
                "name": "WANG Suichan",
                "org": "Lanzhou Central Meteorological Observatory,Lanzhou ,China"
            },
            {
                "name": "LI Zhaorong",
                "org": "Gansu Provincial Weather Modification Office,Lanzhou ,China"
            },
            {
                "name": "FU Shuangxi",
                "org": "Gansu Provincial Weather Modification Office,Lanzhou ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Institute of Arid Meteorology,CMA,Lanzhou ,China"
            },
            {
                "name": "CHU Rongzhong",
                "org": "Cold and Arid Regions Environmental and Engineering Research Institute,CAS,Lanzhou ,China"
            },
            {
                "name": "CHEN Xuhui",
                "org": "Lanzhou Central Meteorological Observatory,Lanzhou ,China"
            }
        ],
        "venue": "Arid Meteorology",
        "year": 2007
    },
    "1cbJkoaO": {
        "id": "1cbJkoaO",
        "title": "The response of three crop drought indices to spring wheat water stress over semi-arid region in northwest China",
        "abstract": "Aimed at severe crop water stress over semi-arid region in Northwest China, Some physiological and environmental parameters are observed during the Spring wheat's flowering and ripe period by CI301-PS photosynthesis instrument,the observation lasts for 1 month, based on the observed value, crop water stress index (CWSI) is calculated, and leaf water potential (LWP)is evaluated. The variations of CWSI, LWP and stomatic conduction with the time and climate change are analyzed. The results show that with the increase of water stress, leaf water will decrease, and CWSI will increase, and leaf water potential will decrease, and stomatic conduction will decrease. As a result, CO2concentration entering stomata will reduce, and the crop net photosynthesis ratio will decrease, and all of these go against biomass accumulation. By Comparison with these three indexes, it is found that CWSI is the worst index responsing to climate change and crop drought, leaf water potential is better than the stomatic conduction. Because of the reverse humidity in the arid regions, it is the most suitable time to observe leaf water potential and stomatic conduction at 9:00 AM. or after 9:00 AM.",
        "keywords": [
            "Crop water stress index",
            "Drought",
            "Leaf water potential",
            "Stomatic conduction",
            "Transpiration rate"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "China Meteorological Administration(China Meteorological Administration,CMA),Beijing,China"
            },
            {
                "name": "Qiang Zhang",
                "org": "China Meteorological Administration(China Meteorological Administration,CMA),Beijing,China"
            },
            {
                "name": "ZHAO Jian-Hua",
                "org": "China Meteorological Administration(China Meteorological Administration,CMA),Beijing,China"
            },
            {
                "name": "Shen Wang",
                "org": "China Meteorological Administration(China Meteorological Administration,CMA),Beijing,China"
            },
            {
                "name": "Hong Zhao",
                "org": "China Meteorological Administration(China Meteorological Administration,CMA),Beijing,China"
            },
            {
                "name": "Jing Wang",
                "org": "China Meteorological Administration(China Meteorological Administration,CMA),Beijing,China"
            }
        ],
        "venue": "Shengtai Xuebao/ Acta Ecologica Sinica",
        "year": 2008
    },
    "vErBD4rc": {
        "id": "vErBD4rc",
        "title": "Influence of Terrain on Precipitation in Qinghai-Tibet Plateau During Summer Monsoon",
        "abstract": "By using high resolution 3″DEM data,precipitation data from May to October of 94 weather stations in the east of Qinghai-Tibet Plateau,based on multivariable stepwise regression method,the estimating model of monthly precipitation are done combined with terrain factors.The result shows that the estimated results of precipitation are very well,relative errors are less than 20%,the correlative coefficient pass the test of 0.95.Under the influence of summer monsoon,the precipitation distribution is different in the north and the south region,and the high value center of precipitation is developed south,moved east and withdraw south,which reflects the transferring law of water-vapor of monsoon.The influence of terrains factors on precipitation is marketable.",
        "keywords": [
            "precipitation in rain season",
            "east of Qinghai-Tibet Plateau",
            "geographical factors",
            "terrain factors",
            "3″DEM"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Key Laboratory of Arid Climatic Changing and Reducing Disaster of Gansu Province"
            },
            {
                "name": "LI Dong-Liang",
                "org": "Key Open Laboratory of Arid Climatic Changing and Disaster Reduction of CMA"
            },
            {
                "name": "WANG Wen",
                "org": "Key Open Laboratory of Arid Climatic Changing and Disaster Reduction of CMA"
            }
        ],
        "venue": "Scientia Geographica Sinica",
        "year": 2008
    },
    "fS1oN1kn": {
        "id": "fS1oN1kn",
        "title": "Preliminary Summary on Parameterization of Heterogeneous Land Surface Process and Remote Sensing Technology Research",
        "abstract": "Heterogeneous land surface has important impact on land surface process model(LSPM) applying.If treated as homogeneous surface,to a great degree,the simulated accuracy of LSPM would be influenced.In this paper the parameterization methods of heterogeneous land surface(Mosaic、statistical-dynamical and other methods) are introduced in detail,the defects of those methods are also analyzed.Then the question of land surface parameter scale conversion is simply discussed.At last the authors give some advice on the advanced study in the future,especially put forward that finding proper method to realize the different scale conversion of land surface parameters is necessary.",
        "keywords": [
            "heterogeneous land surface",
            "land surface process",
            "scale conversion",
            "parameterization methods"
        ],
        "authors": [
            {
                "name": "QIAO Juan",
                "org": "Chinese Academy of Meteorological Sciences,Beijing ,China;Key Laboratory of Arid Climatic Change and Reducing Disaster of Gansu Province,Key Open Laboratory of Arid Climate Change and Disaster Reduction of CMA,Institute of Arid Meteorology,CMA,Lanzhou ,China"
            },
            {
                "name": "ZHANG Qiang",
                "org": "Key Laboratory of Arid Climatic Change and Reducing Disaster of Gansu Province,Key Open Laboratory of Arid Climate Change and Disaster Reduction of CMA,Institute of Arid Meteorology,CMA,Lanzhou ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Key Laboratory of Arid Climatic Change and Reducing Disaster of Gansu Province,Key Open Laboratory of Arid Climate Change and Disaster Reduction of CMA,Institute of Arid Meteorology,CMA,Lanzhou ,China"
            }
        ],
        "venue": "Arid Meteorology",
        "year": 2008
    },
    "p6XBSwCA": {
        "id": "p6XBSwCA",
        "title": "Estimation Method of Ecological Water Use and Relative Questions",
        "abstract": "The issues about ecological water use are summarized from its concept,background,estimation method and research advances.On the basis of the summary,some questions in research at present and the possible breakthrough in mechanism investigation of ecological water use are put forward.At last,it is pointed out that under the background of climate warming and shortage of water resource,the spatial and temporal variation of ecological water use corresponding to supply and demand balance of water resource will become hot scientific issue.",
        "keywords": [
            "issue discussion",
            "ecological water",
            "prospect",
            "estimation method"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Key Laboratory of Arid Climatic Change and Reducing Disaster of Gansu Province"
            },
            {
                "name": "GAO Xuefeng",
                "org": "Key Laboratory of Arid Climate Change and Disaster Reduction of CMA"
            },
            {
                "name": "WANG Runyuan",
                "org": "Institute of Arid Meteorology,CMA,Lanzhou ,China"
            }
        ],
        "venue": "Arid Meteorology",
        "year": 2008
    },
    "cSCIFoYF": {
        "id": "cSCIFoYF",
        "title": "Characteristics of Water Cycle in the Qilian Mountains and the Oases in Hexi Inland River Basins",
        "abstract": "The Qilian Mountains and the Hexi corridor are located in the coupling area of the atmospheric circulations including the southeast monsoon,the westerly,and the plateau monsoon.The characteristics of water cycle over Hexi inland river basins are remarkably influenced by the atmospheric circulation systems.The relationship between annual precipitation and altitude,and general circulation system affecting the Qilian Mountains and the oases in the inland river irrigation areas are analyzed by using the observational data of meteorology,hydrology,geography,agriculture and ecology etc.The distribution characteristics of horizontal scale of oases maintained by inland rivers,the impact of terrain height on surface evaporation and density of vegetation,and the relationship of average water consumption ratio and irrigation ratio in oases are revealed.Finally,the characteristics of the oases in Hexi inland river basins and the ideas about exploitation and protection of the oases are preliminarily discussed.",
        "keywords": [
            "oasis distribution and water consumption",
            "atmospheric circulation systems",
            "characteristics of water cycle",
            "Qilian Mountains and Hexi inland river basins"
        ],
        "authors": [
            {
                "name": "ZHANG Qiang",
                "org": "Gansu Province Key Laboratory of Arid Climatic Changes and Disaster Reduction,Institute of Arid Meteorology,China MeteorologicalAdministration,Key Open Laboratory of Arid Climatic Changing and Disaster Reduction of China Meteorological Adminstration,Lanzhou Gansu ,China;Department of Atmospheric Science,Lanzhou University,Lanzhou Gansu ,China"
            },
            {
                "name": "YU Ya-xun",
                "org": "Gansu Province Key Laboratory of Arid Climatic Changes and Disaster Reduction,Institute of Arid Meteorology,China MeteorologicalAdministration,Key Open Laboratory of Arid Climatic Changing and Disaster Reduction of China Meteorological Adminstration,Lanzhou Gansu ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Gansu Province Key Laboratory of Arid Climatic Changes and Disaster Reduction,Institute of Arid Meteorology,China MeteorologicalAdministration,Key Open Laboratory of Arid Climatic Changing and Disaster Reduction of China Meteorological Adminstration,Lanzhou Gansu ,China;Department of Atmospheric Science,Lanzhou University,Lanzhou Gansu ,China"
            }
        ],
        "venue": "Journal of Glaciology and Geocryology",
        "year": 2008
    },
    "4YZHLKp5": {
        "id": "4YZHLKp5",
        "title": "MODIS Retrieval of Different Vegetation LAI and Its Application to the East of Qinghai-Xizang Plateau",
        "abstract": "Combined MODIS data from Terra and Aqua satellites with Iaquinta and Pinty model and land cover product,LAI of 6 type biology communities in the east of Qinghai-Xizang Plateau is retrieved,moreover,contrast of LAI with observed LAI from Li-3000 instrument have been done.The results show that LAI can be retrieved by the 8 day-long data of two satellites,relative error of retrieval result is less than 20%,averaged relative error is 13.7%,which means that this method can be used for retrieval of LAI.According to difference of vegetation type,exponent relations of LAI with NDVI of 6 type biology community have been formed,the relativity is good.Temporal series of LAI of different vegetation types are not in agreement with each other,which show difference of growth period of biology character,spatial distribution of LAI is also different,which means that the climate is different in the various regions.",
        "keywords": [
            "Multi-temporal and multi-angle observed data",
            "Qinghai-Xizang Plateau",
            "LAI",
            "MODIS",
            "6 type biology communities"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Key Laboratory of Arid Climatic Changing and Reducing Disaster of Gansu Province,Key Open Laboratory ofArid Climatic Changing and Disaster Reduction of China Meteorological Administralion,Lanzhou Institute ofArid Meteorology,China Meteorological Administration,Lanzhou ,China"
            },
            {
                "name": "ZHANG Qiang",
                "org": "Key Laboratory of Arid Climatic Changing and Reducing Disaster of Gansu Province,Key Open Laboratory ofArid Climatic Changing and Disaster Reduction of China Meteorological Administralion,Lanzhou Institute ofArid Meteorology,China Meteorological Administration,Lanzhou ,China"
            },
            {
                "name": "LI Dong-liang",
                "org": "College of AtmosphericScience,Nanjing University of Information Science and Technology,Nanjing ,China"
            },
            {
                "name": "WANG Wen",
                "org": "College of AtmosphericScience,Nanjing University of Information Science and Technology,Nanjing ,China"
            }
        ],
        "venue": "Plateau Meteorology",
        "year": 2008
    },
    "uTIcv7Vi": {
        "id": "uTIcv7Vi",
        "title": "Some Technological and Scientific Issues about the Experimental Study of Land Surface Processes in Chinese Loess Plateau(LOPEX)",
        "abstract": "In this paper,some technological and scientific issues the experimental study of land surface deals with in Chinese loess plateau are discussed.At first,the important meanings of the experimental study of land surface processes in Chinese loess plateau are explained in science and practice.And its research aspects and technological and scientific issues in field observation and analysis of land surface processes in Chinese loess plateau,characteristics of land surface water processes and its impact on physiological and ecological processes,parameterizations of land surface processed are introduced.Finally,the technological and scientific difficulties of experimental study and some thought of their solutions are discussed.",
        "keywords": [
            "Land surface processes",
            "Parameterizations.",
            "Coupling of spatial scales",
            "Loess plateau",
            "Experimental study"
        ],
        "authors": [
            {
                "name": "ZHANG Qiang",
                "org": "Institute of Arid Meteorology,CMA;Lanzhou Univerrsity,Lanzhou ,China;Chinese Academy of Meteorological Sciences,China Meteorological Administration,Beijing ,China"
            },
            {
                "name": "HU Xiangjun",
                "org": "Lanzhou Central Meteorological Observatory,Lanzhou ,China"
            },
            {
                "name": "WANG Sheng",
                "org": "Institute of Arid Meteorology,CMA;Lanzhou Univerrsity,Lanzhou ,China"
            },
            {
                "name": "LIU Hongyi",
                "org": "Institute of Arid Meteorology,CMA"
            },
            {
                "name": "ZHANG Jie",
                "org": "Institute of Arid Meteorology,CMA;Lanzhou Univerrsity,Lanzhou ,China"
            },
            {
                "name": "WANG Runyuan",
                "org": "Institute of Arid Meteorology,CMA;Lanzhou Univerrsity,Lanzhou ,China"
            }
        ],
        "venue": "Advances in Earth Science",
        "year": 2009
    },
    "aThL5RWH": {
        "id": "aThL5RWH",
        "title": "Evaluation and analysis of latent heat in rainy season in Qinghai-Xizang Plateau",
        "abstract": "Combined with the 3″DEM data and the precipitation data in rainy season (from May to September) at 102 weather stations in the east of Qinghai-Xizang Plateau, we have divided the stations into three classes according to the precipitation distribution with altitude. The models of the relationships between the precipitation and various geographical and topographical factors were built up based on regression analysis, and the precipitation and latent heat of condensation in rainy season were evaluated over the past 46 years (1961-2006). The results showed that the correlation between the precipitation and those factors are remarkable; the correlation coefficients are 0.69, 0.82, 0.90, respectively, which past the 0.05 confidence test. The distribution of latent heat of condensation is inhomogeneous in the east of the plateau, that is, higher in the southeast of the plateau and lower in the northwest of the plateau. The east of the plateau is divided into 5 climate sub-areas by using EOF and REOF methods; the temporal variation in total latent heat of condensation of the east plateau is in consistent with the latent heat of condensation in A,B,E regions, but is inconsistent with the latent heat of condensation in C, D regions.The total latent heat ranges from 18.1×1020 J to 26.8×1020 J; the trend of its variation is increasing; the average latent heat is 21.9×1020 J. Because of the positive adjusting effect of altitude, longitude and slope gradient and other factors on precipitation in lower altitude regions, the latent heat of condensation in these regions are decreasing since 1990's. Because of the positive adjusting effect of slope gradient and the negative adjusting effect of latitude on precipitation in high altitude regions, the latent heat of condensation in these regions are increasing with fluctuations.",
        "keywords": [
            "topographical factors",
            "latent heat in rainy season",
            "east of Qinghai-Xizang Plateau",
            "geographical factors",
            "3″DEM"
        ],
        "authors": [
            {
                "name": "Zhang Jie",
                "org": "Nanjing University of Information Science and Technology, Nanjing , China2.Key Laboratory of Arid Climatic Changing and Reducing Disaster of Gansu Province; Key Open Laboratory of Arid Climatic Changing and Disaster Reduction of CMA, Institute of Arid Meteorology, China Meteorological Administration, Lanzhou , China"
            },
            {
                "name": "Li Dongliang",
                "org": "Nanjing University of Information Science and Technology, Nanjing , China2.Key Laboratory of Arid Climatic Changing and Reducing Disaster of Gansu Province"
            }
        ],
        "venue": "Earth Science Frontiers",
        "year": 2009
    },
    "fR52oHRn": {
        "id": "fR52oHRn",
        "title": "The Progresses on Land Surface Processes and Atmospheric Boundary Layer in Arid Regions",
        "abstract": "Land surface processes and atmospheric boundary layer in arid regions in China as a key physical process are not only closely related with the regional climate,ecology,water resource,but also have impact on the pattern of China climate and Eastern-Asian atmospheric circulation.In recent years,many researches about the issues have been done,and a lot of progresses have been obtained.In this paper,the several aspects of research progresses,including thermodynamic and hydrological characteristics of surface land processes in arid regions,structure of atmospheric boundary layer in arid regions,parameters and parameterization of surface land processes in arid regions,theory of atmospheric boundary layer of heterogeneous underlying surface,the characteristics of atmospheric boundary layer and pollutant mechanism of a arid valley city,etc.have been summarized and concluded.And the present scientific problems and the future important scientific points are discussed.",
        "keywords": [
            "Arid regions",
            "Atmospheric boundary layer.",
            "Land surface progresses"
        ],
        "authors": [
            {
                "name": "ZHANG Qiang",
                "org": "Institute of Arid Meteorology,CMA;Gansu Provincial Meteorological Bureau,Lanzhou ,China;Lanzhou University,Lanzhou ,China"
            },
            {
                "name": "WANG Sheng",
                "org": "Institute of Arid Meteorology,CMA;Lanzhou University,Lanzhou ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Institute of Arid Meteorology,CMA;Lanzhou University,Lanzhou ,China"
            },
            {
                "name": "WANG Runyuan",
                "org": "Institute of Arid Meteorology,CMA;Lanzhou University,Lanzhou ,China"
            },
            {
                "name": "LIU Hongyi",
                "org": "Institute of Arid Meteorology,CMA"
            },
            {
                "name": "LI Yanying",
                "org": "Institute of Arid Meteorology,CMA;Lanzhou University,Lanzhou ,China"
            }
        ],
        "venue": "Advances in Earth Science",
        "year": 2009
    },
    "95rLXOi3": {
        "id": "95rLXOi3",
        "title": "On Measuring Methods and Exploitation Technology for Dewfall on Land Surface",
        "abstract": "Based on systematically summarizing previous some measuring methods and observational instruments for magnitude of dewfall on land surface,the characteristics of common observational instru-ment of land surface dewfall have been introduced,and several basic measurement methods for dew have been generalized.Moreover,the basic principle of those methods and instrument are interpreted,and their advantages,disadvantages and applicability have also been analyzed.At the same time,the further im-provement of the observational instruments and the development of measuring method for dewfall have been put forward.Finally,technical measures and scientific proposals for exploitating dewfall have been given out.",
        "keywords": [
            "Exploitation technology",
            "Land surface",
            "Measuring methods",
            "Dewfall",
            "Observational instrument"
        ],
        "authors": [
            {
                "name": "ZHANG Qiang",
                "org": "Institute of Arid Meteorology,China Meteorological Adminstration/Key laboratory of Arid Climatic Change and Reducing Disaster of Gansu Province/Key Open Laboratory of Arid Climatic Change and Disaster Reduction of China Meteoroogical Adminstration,Lanzhou,China"
            },
            {
                "name": "WEN Xiao-mei",
                "org": "Institute of Arid Meteorology,China Meteorological Adminstration/Key laboratory of Arid Climatic Change and Reducing Disaster of Gansu Province/Key Open Laboratory of Arid Climatic Change and Disaster Reduction of China Meteoroogical Adminstration,Lanzhou,China;Chinese Academy of Meteorological Sciences,China Meteorological Administration,Beijing,China"
            },
            {
                "name": "WANG Sheng",
                "org": "Institute of Arid Meteorology,China Meteorological Adminstration/Key laboratory of Arid Climatic Change and Reducing Disaster of Gansu Province/Key Open Laboratory of Arid Climatic Change and Disaster Reduction of China Meteoroogical Adminstration,Lanzhou,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Institute of Arid Meteorology,China Meteorological Adminstration/Key laboratory of Arid Climatic Change and Reducing Disaster of Gansu Province/Key Open Laboratory of Arid Climatic Change and Disaster Reduction of China Meteoroogical Adminstration,Lanzhou,China"
            }
        ],
        "venue": "Plateau Meteorology",
        "year": 2010
    },
    "RbEw1wOo": {
        "id": "RbEw1wOo",
        "title": "Remote Sensing Research of Snow Cover Distribution and Variation in Qilian Mountains in the Winter Half Year of 1996—2002",
        "abstract": "Using the dekad snow cover data in the winter half year of 1996-2002 provided by National Satellite Meteorological Center,combined with the temperature and snow data observed by meteorological ground stations and the DEM data of Qilian Mountains,the distribution and variation characteristics of snow cover in Qilian Mountains are studied.The results showed that the snow cover in Qilian Mountains had a band distribution with the mountains orientation in the winter half year,in ridge area with more snow,but in the valley and southen basin less.The characteristic of distribution frequency is that the highest is in west segment,then in east segment and the lowest in middle segment.The basic trend of average distribution height of different frequency snow cover is that the higher the snow cover frequency is,the higher the distributing height is.As far for the snow cover of different frequencies,the lower frequency takes the larger proportion. For mean snow cover frequency,the east and middle segments both is reducing trend reduced before the winter half year of 1998/1999 while increased after it,and the increment of mean snow cover frequency in east and middle segments are quite close,while the west segment increased in the winter half year of 1996/1997,and its mean snow cover frequency is higher than the east and middle segments significantly.The snow cover of three segments all increase as the height increases,only in middle segment of 1999 —2001 didn′t increase with height increasing apparently,it might has relation with the complex effects of weather system and topography in middle segment.",
        "keywords": [
            "Qilian Mountains",
            "Coverage",
            "Remote sensing",
            "Snow frequency"
        ],
        "authors": [
            {
                "name": "WANG Xing",
                "org": "Institute of Arid Meteorology,China Meteorological Administration/Key Laboratory of Arid Climatic Change and Reducing Disaster of Gansu Province/Key Open Laboratory of Arid Climate Change and Disaster Reduction of China Meteorological Administration,Lanzhou ,China"
            },
            {
                "name": "ZHANG Qiang",
                "org": "Institute of Arid Meteorology,China Meteorological Administration/Key Laboratory of Arid Climatic Change and Reducing Disaster of Gansu Province/Key Open Laboratory of Arid Climate Change and Disaster Reduction of China Meteorological Administration,Lanzhou ,China"
            },
            {
                "name": "GUO Ni",
                "org": "Institute of Arid Meteorology,China Meteorological Administration/Key Laboratory of Arid Climatic Change and Reducing Disaster of Gansu Province/Key Open Laboratory of Arid Climate Change and Disaster Reduction of China Meteorological Administration,Lanzhou ,China"
            },
            {
                "name": "CAI Di-hua",
                "org": "Institute of Arid Meteorology,China Meteorological Administration/Key Laboratory of Arid Climatic Change and Reducing Disaster of Gansu Province/Key Open Laboratory of Arid Climate Change and Disaster Reduction of China Meteorological Administration,Lanzhou ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Institute of Arid Meteorology,China Meteorological Administration/Key Laboratory of Arid Climatic Change and Reducing Disaster of Gansu Province/Key Open Laboratory of Arid Climate Change and Disaster Reduction of China Meteorological Administration,Lanzhou ,China"
            },
            {
                "name": "CHEN Qian",
                "org": "Gansu Weather Modification Office,Lanzhou ,China"
            },
            {
                "name": "TANG Mao-cang",
                "org": "Laboratory for Climate Environment and Disasters of Western China,Cold and Arid Regions Environmental and Engineering Research Institute,Chinese Academy of Sciences,Lanzhou ,China"
            }
        ],
        "venue": "Plateau Meteorology",
        "year": 2010
    },
    "ZUEuXQcS": {
        "id": "ZUEuXQcS",
        "title": "An improvement of localization in the retrieval algorithm of temperature profile within boundary layer",
        "abstract": "Using the statistical synthetic regression algorithm by the USA,the temperature and moisture profile of the atmosphere is retrieved based on the MODIS data,which,as an initial condition,is then employed for estimating the atmosphere transmittance through Pressure-Layer Fast Algorithm for Atmospheric Transmittances(PFAAST),and thus the atmosphere temperature is retrieved via the nonlinear physical retrieval algorithm.The results show that the atmospheric temperature error is within 2 K at and above the top of boundary layer with a larger error within boundary layer,that is positively correlated with the aerosol optical depth(AOD) increment as well as the estimated error of surface temperature,but with poor correlation with atmospheric moisture mixing ratio.On the basis of the radiative transfer theory and sensible experiments,the effect of AOD and surface temperature on retrieval error is analyzed with the result that the surface temperature weighting to different spectral band is enhanced with increasing surface retrieval error,suggesting that a reasonable surface temperature precision is helpful for improving surface temperature weighting.Aerosol concentration is high within the boundary layer over the desert and the Gobi region in the northwestern China,which reduces the atmospheric transmittance therein.Besides,the surface temperature weighting and air temperature weighting to infrared band should be decreased in case the infrared remote sensing data are used.In view of that the sand aerosol effect within boundary layer is omitted,the atmosphere transmittance retrieved is overestimated and thus the surface temperature weighting and air temperature weighting are overestimated as well, causing that the air temperature retrieved is underestimated.According to the observed aerosol optical depth from sunphotometer,an improvement in the AOD effect and thus the surface temperature is obtained resulting from improved temperature profile that is able to reflect the real atmosphere structure within boundary layer.",
        "keywords": [
            "Temperature profile",
            "Aerosol",
            "Boundary layer",
            "Statistical and physical algorithm",
            "Surface temperature"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": " 1.Key Laboratory of Meteorological Disaster%%#KLMD%%#,Ministry of Education and Jiangsu Province,Nanjing University of Information Science and Technology,Nanjing ,China 2.Institute of Arid Meteorology,China Meteorological Administration,Lanzhou ,China 3.University of Wisconsin-Madison,Madison,Wisconsin 53706,USA"
            },
            {
                "name": "ZHANG Qiang",
                "org": " 1.Key Laboratory of Meteorological Disaster%%#KLMD%%#,Ministry of Education and Jiangsu Province,Nanjing University of Information Science and Technology,Nanjing ,China 2.Institute of Arid Meteorology,China Meteorological Administration,Lanzhou ,China 3.University of Wisconsin-Madison,Madison,Wisconsin 53706,USA"
            },
            {
                "name": "LI Jun",
                "org": " 1.Key Laboratory of Meteorological Disaster%%#KLMD%%#,Ministry of Education and Jiangsu Province,Nanjing University of Information Science and Technology,Nanjing ,China 2.Institute of Arid Meteorology,China Meteorological Administration,Lanzhou ,China 3.University of Wisconsin-Madison,Madison,Wisconsin 53706,USA"
            }
        ],
        "venue": "Acta Meteorologica Sinica",
        "year": 2010
    },
    "uZP192nA": {
        "id": "uZP192nA",
        "title": "Application of Aerodynamic Resistance Arithmetic in Semi-Arid Region of China and Retrival from Remote Sensing",
        "abstract": "Combined with observed data at Dingxi station in semi-arid region of China,9 kinds aerodynamic resistance arithmetic are used for estimating aerodynamics resistance,the sensible heat flux is estimated based on these resistance results,the contrasts of eddy correlation results with other arithmetic results are performed,and the seasonal variable is estimated.The conclusions are:(1) Due to higher temperature,less precipitation and lower air humidity during vegetation growing season in sparse vegetation region in Loess Plateau and semi-arid region of northwest China,heat exchange and water vapor exchange are particular and not neglected,the sensible heat flux and aerodynamic resistance arithmetic Choudh-1,Verma-R are the same with aerodynamic resistance of these region because of perfect describing of heat,momentum and water vapor exchange.(2) Aerodynamic resistance was mainly influenced not only by wind speed but also by vegetation fraction due to increasing roughness length.(3)Aerodynamic resistance is well retrieved from remote sensing by using choudh-1 arithmetic.",
        "keywords": [
            "Wind speed",
            "Sparse vegetation",
            "Aerodynamic resistance",
            "Sensible heat flux"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Key Laboratory of Meteorological Disaster,Ministry of Education and Jiangsu Province/Nanjing University ofInformation Science & Technology,Nanjing ,China"
            },
            {
                "name": "ZHANG Qiang",
                "org": "Institute of Arid Meteorology,China Meteorological Administration,Lanzhou ,China"
            },
            {
                "name": "HUANG Jian-ping",
                "org": "College of Atmosphere Science,Lanzhou University,Lanzhou ,China"
            }
        ],
        "venue": "Plateau Meteorology",
        "year": 2010
    },
    "Mzr9wcI4": {
        "id": "Mzr9wcI4",
        "title": "Comparison of Atmospheric Boundary Layer in Winter and Summer over Arid Region of Northwest China",
        "abstract": "The vertical structural characteristics of main physical factors over arid region of northwest China in winter and summer are analyzed based on the field intensive observation data of atmospheric boundary layer (ABL) in Dunhuang during the period of 28 June to 17 July 2006 and 1 Jan.to 10 Jan.2007.The results show that structure of ABL is similar in the two seasons,whereas the depth in summer is obviously thicker than that in winter.In summer,the maximal depth of convective boundary layer (CBL) exceeds 3 500 m and the stable boundary layer (SBL) can reach 900 m generally.However,in winter,the maximum depth of CBL and SBL is 2 350 m and 500 m lower than that in summer,respectively.Which indicates the particular deep structure of ABL generally exists in summer,but do not occur in winter.Moreover,the variation of humidity with height in summer is more significant than that in winter.The humidity inversion phenomenon in winter appears from ground surface,whereas in summer it takes place at heights of 60 to 100 m.What's more,both in summer and winter the wind velocity always shows Ekman spiral characteristic clearly from daytime to nighttime.The geo-strophic wind in summer and daytime is higher than that in winter and nighttime respectively.",
        "keywords": [
            "winter",
            "structure of the atmospheric boundary layer",
            "summer",
            "arid region of Northwest China"
        ],
        "authors": [
            {
                "name": "QIAO Juan",
                "org": "Institute of Arid Meteorology,China Meteorological Administration,Key Laboratory of Arid Climate Change and Reducing Disaster of Gansu Province & Open Key Laboratory of Arid Climate Change and Reducing Disaster of CMA,Lanzhou ,China;Xi'an Meteorological Bureau,Xi'an ,China"
            },
            {
                "name": "ZHANG Qiang",
                "org": "Institute of Arid Meteorology,China Meteorological Administration,Key Laboratory of Arid Climate Change and Reducing Disaster of Gansu Province & Open Key Laboratory of Arid Climate Change and Reducing Disaster of CMA,Lanzhou ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Institute of Arid Meteorology,China Meteorological Administration,Key Laboratory of Arid Climate Change and Reducing Disaster of Gansu Province & Open Key Laboratory of Arid Climate Change and Reducing Disaster of CMA,Lanzhou ,China"
            },
            {
                "name": "WANG Sheng",
                "org": "Institute of Arid Meteorology,China Meteorological Administration,Key Laboratory of Arid Climate Change and Reducing Disaster of Gansu Province & Open Key Laboratory of Arid Climate Change and Reducing Disaster of CMA,Lanzhou ,China"
            }
        ],
        "venue": "Journal of Desert Research",
        "year": 2010
    },
    "mYoV8xpt": {
        "id": "mYoV8xpt",
        "title": "Research Progress of the Extracting Method and Refining Technology of Grape Seed Oil",
        "abstract": "The grape seeds are separated from the leftovers in the wine produced process.The crude oil can be obtained from the grape seeds,by adopting the methods of squeezing,solvent extraction or supercritical fluid extraction.Then the crude oil are refined by degumming,deacidifying,water cleaning and drying,decoloring,deodorizing,characteristic filtering,and so on,to give the refined product oil.The research progress of the extracting method and refining technology of grape seed oil are reviewed.",
        "keywords": [
            "supercritical fluid extraction",
            "grape seeds",
            "solvent extraction",
            "squeezing"
        ],
        "authors": [
            {
                "name": "YANG Hui-lin",
                "org": "College of Chemical Engineering,Zhengzhou University, Zhengzhou ,China"
            },
            {
                "name": "CHEN Wei-hang",
                "org": "College of Chemical Engineering,Zhengzhou University, Zhengzhou ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "College of Chemical Engineering,Zhengzhou University, Zhengzhou ,China"
            }
        ],
        "venue": "Henan Chemical Industry",
        "year": 2006
    },
    "E9zaRvPC": {
        "id": "E9zaRvPC",
        "title": "The actuality of corn embryo oil and its charactors",
        "abstract": "The withdrawing methods of corn embryo oil are summarized.The methods consisted of water replacing,squeeezing and water enzymolysis.By its stability and biological function,the characters of the corn embryo oil not only point to the function of reducing the cholesterol,but also have strong oxidizing stability.Therefore,it has broad market prosp ect.",
        "keywords": [
            "water enzymolysis",
            "water replacing",
            "corn embryo oil",
            "squeezing",
            "oxidizing stability",
            "cholesterol"
        ],
        "authors": [
            {
                "name": "WANG Su-min",
                "org": "College of Chem.Eng.,Zhengzhou Univ.,Zhengzhou ,China"
            },
            {
                "name": "ZHANG Pei",
                "org": "College of Chem.Eng.,Zhengzhou Univ.,Zhengzhou ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "College of Chem.Eng.,Zhengzhou Univ.,Zhengzhou ,China"
            },
            {
                "name": "CHEN Wei-hang",
                "org": "College of Chem.Eng.,Zhengzhou Univ.,Zhengzhou ,China"
            }
        ],
        "venue": "Journal of Zhengzhou University of Light Industry(Natural Science)",
        "year": 2007
    },
    "IhIR0a91": {
        "id": "IhIR0a91",
        "title": "Effects of Food Additives on the Stability of Gardenia Yellow Pigment",
        "abstract": "This paper used the method of adding composite food additives,firstly,in order to improve the stability of gardenia yellow pigment.In this study,the author used the gardenia fruit used in medicine as the studied material to extract gardenia yellow pigment.It studied the effects of twelve kinds of food additives and seven kinds of composite food additives on the stability of gardenia yellow pigment and confirmed the optimal food additives and composite food additives.The results showed that singel alginate and sodium can be better to stabilize the molecular structure of this pigment than EDTA-Na2,reported in literature;and the association of alginate and sodium is better for the pigment's stability.The pigment solution added alginat,sodium and sodium tartrate is the best in all samples.",
        "keywords": [
            "gardenia yellow pigment",
            "food additives",
            "stability",
            "composite"
        ],
        "authors": [
            {
                "name": "CHEN Wei-hang",
                "org": "School of Chemical Engineering,Zhengzhou University,Zhengzhou ,China"
            },
            {
                "name": "LIU Rui-ying",
                "org": "School of Chemical Engineering,Zhengzhou University,Zhengzhou ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "School of Chemical Engineering,Zhengzhou University,Zhengzhou ,China"
            },
            {
                "name": "ZHOU Ji-min",
                "org": "School of Chemical Engineering,Zhengzhou University,Zhengzhou ,China"
            },
            {
                "name": "DOU Chong",
                "org": "School of Chemical Engineering,Zhengzhou University,Zhengzhou ,China"
            }
        ],
        "venue": "Journal of Zhengzhou University(Engineering Science)",
        "year": 2009
    },
    "ABn2By7d": {
        "id": "ABn2By7d",
        "title": "The Preparation of Composite NF Membrane by the Interfacial Polymerization between Chitosan and Trimesoyl Chloride",
        "abstract": "In order to realize efficient desalinization of low molecular weight organics, a composite NF membrane was prepared by the interfacial polymerization (IP) between chitosan (CS) and trimesoyl chloride (TMC) on the surface of PSF/PES blend membrane. The SEM micrographs show that the IP reaction can form a compact selective layer on the surface of the basement membrane, and the FT-IR spectra reveal that the above reaction results from acylation reactions between the –NH2 of CS and acid chloride group of TMC. As to the prepared composite NF membrane, with increasing the CS or TMC concentration, the IP time and the heat treatment temperature, its water flux reduces and its retentions of both organics and salts increase. The optimized IP technologic conditions were found as follows: the basement membrane after being immersed in 0.5%(wt) CS solution for 10 min was interfacial polymerized with 0.2%(wt) TMC for 2 min, and then the heat treatment was conducted for 10 min at 70℃ followed by soaking in 0.2%(wt) SDS solution for 2 h. Using above optimized technologic conditions, the prepared composite NF membrane shows that its retention of polyethyleneglycol 2000 is 92%, while its retentions of NaCl 、MgCl2 、MgSO4 and Na2SO4 are 7.8% 、 19.4% 、23% and 32.8%, respectively. It indicates that this composite NF membrane can be used to separate the salts from the low molecular weight organics efficiently.",
        "keywords": [
            "composite NF membrane",
            "interfacial polymerization",
            "trimesoyl chloride(TMC)",
            "chitosan(CS)"
        ],
        "authors": [
            {
                "name": "ZHANG Hao-qin",
                "org": "Zhengzhou University, College of Chemical Engineering, Zhengzhou , China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Zhengzhou University, College of Chemical Engineering, Zhengzhou , China"
            },
            {
                "name": "ZHU Yan-qing",
                "org": "Zhengzhou University, College of Chemical Engineering, Zhengzhou , China"
            },
            {
                "name": "LIU Jin-dun",
                "org": "Zhengzhou University, College of Chemical Engineering, Zhengzhou , China"
            },
            {
                "name": "FANG Wen-ji",
                "org": "Zhengzhou University, College of Chemical Engineering, Zhengzhou , China"
            }
        ],
        "venue": "Journal of Chemical Engineering of Chinese Universities",
        "year": 2009
    },
    "sF1SRqZ2": {
        "id": "sF1SRqZ2",
        "title": "Study on Extraction Procedure of Proanthocyandins from Hibiscus Syriacus Linn",
        "abstract": "The content of proanthocyandins from the flowers of Hibiscus syriacus Linn was regarded as the index of examination.This paper studied the concentration of ethanol,temperature,solid-liquid ratio and time of extraction as factors influencing the extraction.According to orthogonal test,the optimal extraction conditions of proanthocyandins were showed as follows:the concentration of ethanol was 90%,the temperature of extraction was 70 ℃,the time of extraction was 30 minutes and the solid-liquid ratio was 1∶ 9.",
        "keywords": [
            "proanthocyandins",
            "Hibiscus syriacus Linn",
            "extracting",
            "orthogonal experiment"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "School of Chemical and Energy Engineering,Zhengzhou University,Zhengzhou ,China"
            },
            {
                "name": "LI Rui-guang",
                "org": "School of Chemical and Energy Engineering,Zhengzhou University,Zhengzhou ,China"
            },
            {
                "name": "CHEN Wei-hang",
                "org": "School of Chemical and Energy Engineering,Zhengzhou University,Zhengzhou ,China"
            }
        ],
        "venue": "Journal of Zhengzhou University(Engineering Science)",
        "year": 2009
    },
    "BCsvrwG6": {
        "id": "BCsvrwG6",
        "title": "Study on the New Purification of HSYA",
        "abstract": "The purification of safflower extraction on three separate process such as the combination of the ultrafiltration,macroporous resin with nanofiltratin,the ultrafiltration with nanofiltratin and macroporous resin with nanofiltratin are discussed,to lay the foundation for preparing high purity,high value-added hydroxy safflower yellow A(hereinafter referred to as HSYA) product.Using the purity of the HSYA as observation index,high performance liquid chromatography(HPLC) are used to measured the HSYA purity in different process routes of the product obtained,and used UV spectrophotometer to monitor the product concentration of every step on line.Experiment selected HPD200A macroporpus resin models,the PES10 membrane and the NF200-400 models of nanofiltration membranes.It is the first use the process route that the combination of ultrafiltration,macroporous resin with nanofiltratin to obtained HSYA,and the final product purity is 58.25%.",
        "keywords": [
            "safflower",
            "HSYA",
            "separating membrane",
            "macroporous resin"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "School of Chemical Engineering and Energy,Zhengzhou University,Zhengzhou ,China"
            },
            {
                "name": "LI Yun-Yun",
                "org": "School of Chemical Engineering and Energy,Zhengzhou University,Zhengzhou ,China"
            },
            {
                "name": "SUN Shu-pei",
                "org": "School of Chemical Engineering and Energy,Zhengzhou University,Zhengzhou ,China"
            },
            {
                "name": "CHEN Wei-hang",
                "org": "School of Chemical Engineering and Energy,Zhengzhou University,Zhengzhou ,China"
            }
        ],
        "venue": "Henan Chemical Industry",
        "year": 2011
    },
    "WzNaKuxd": {
        "id": "WzNaKuxd",
        "title": "Research on the process of recovering discarded polysulfone membranes by means of dissolution-precipitation method",
        "abstract": "At the beginning of this experiment,we have studied on the recovering of polysulfone (PSF) from unpolluted PSF hollow fiber membranes by means of dissolution-precipitation method.We chose humic acid,inorganic ions and protein,which are main pollutants in waste water,as pollutants in the beginning of our contaminate experiments.We also polluted the polysulfone membrane by using real landfill leachate.The results of our experiments show that, the protein and humic acid have little effect on the PSF purity and PSF recovery.Though the mixture of humic acid and inorganic ions and the real landfill leachate have greatly effects on the PSF purity,PSF recovery can still be above 80%.It shows that,the means of dissolution- precipitation method has practical application value for the recovering discarded polysulfone membranes.",
        "keywords": [
            "dissolution-precipitation",
            "membrane polluting",
            "polysulfone"
        ],
        "authors": [
            {
                "name": "XU Xiaohe",
                "org": "School of Chemical Engineering,Zhengzhou University,Zhengzhou ,Henan,China"
            },
            {
                "name": "CHEN Weihang",
                "org": "School of Chemical Engineering,Zhengzhou University,Zhengzhou ,Henan,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "School of Chemical Engineering,Zhengzhou University,Zhengzhou ,Henan,China"
            },
            {
                "name": "LIU Yang",
                "org": "School of Chemical Engineering,Zhengzhou University,Zhengzhou ,Henan,China"
            },
            {
                "name": "REN Xiaojing",
                "org": "School of Chemical Engineering,Zhengzhou University,Zhengzhou ,Henan,China"
            }
        ],
        "venue": "Chemical Industry and Engineering Progress",
        "year": 2011
    },
    "9t3Z6HJv": {
        "id": "9t3Z6HJv",
        "title": "Optimizing Procyanidins Extraction from Lotus Seed Pot with Response Surface Methodology",
        "abstract": "On the basis of single-factor test,the response surface methodology(RSM) with 4 factors and 3 levels was adopted to optimize ethanol extraction technology of procyanidins from Lotus Seed Pot(LSPC).The interactive effects of the parameters on LSPC yield were investigated.Design Expert 7.1.6 software was used to fit experimental data and a quadratic polynomial regression model was developed for LSPC yield as a response to the parameters.Results showed that the optimal value of extraction conditions were as follows: ethanol concentration 50%,solvent/material ratio 25 mL/g,extraction temperature 55℃and extraction time 60 min.Under such conditions and extraction 1 time,the yield of LSPC was up to 6.678 mg/100 g,which is close to the predictive yield(6.693 mg/100 g).This model is reasonable and reliable,and can be used in the actual forecast.",
        "keywords": [
            "lotus seed pot",
            "extraction technology",
            "procyanidins",
            "response surface methodology"
        ],
        "authors": [
            {
                "name": "CHEN Wei-hang",
                "org": "School Chemical Engineering and Energy,Zhengzhou University,Zhengzhou ,China"
            },
            {
                "name": "TAN Mei-ting",
                "org": "School Chemical Engineering and Energy,Zhengzhou University,Zhengzhou ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "School Chemical Engineering and Energy,Zhengzhou University,Zhengzhou ,China"
            }
        ],
        "venue": "Journal of Zhengzhou University(Engineering Science)",
        "year": 2012
    },
    "Yg5lcY2R": {
        "id": "Yg5lcY2R",
        "title": "Reform on the Curriculum System and Teaching Content of Chemical Engineering and Technology",
        "abstract": "In order to adapt to the new development situation of China's higher education,and to meet the needs of training talents for the country and society in new century,the profession of chemical engineering and technology in Zhengzhou University as a pilot,reforms on curriculum system and teaching content,and constructs the curriculum system with \"Platform+ Module+ Curriculum Group\":platform reflects thick foundation and wide caliber;module reflects the cultivation of basic professional quality and ability;curriculum group enlarges students' vision,and reflects innovation.The new teaching plan is implemented and has initial success in 2009 freshmen.",
        "keywords": [
            "module",
            "curriculum system and teaching content",
            "technology",
            "the profession of chemical engineering",
            "curriculum group"
        ],
        "authors": [
            {
                "name": "HOU Cui-hong",
                "org": "School of Chemical Engineering and Energy,Zhengzhou University,Zhengzhou,,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "School of Chemical Engineering and Energy,Zhengzhou University,Zhengzhou,,China"
            },
            {
                "name": "CHEN Wei-hang",
                "org": "School of Chemical Engineering and Energy,Zhengzhou University,Zhengzhou,,China"
            },
            {
                "name": "TANG Jian-wei",
                "org": "School of Chemical Engineering and Energy,Zhengzhou University,Zhengzhou,,China"
            },
            {
                "name": "REN Bao-zeng",
                "org": "School of Chemical Engineering and Energy,Zhengzhou University,Zhengzhou,,China"
            },
            {
                "name": "WAN Ya-zhen",
                "org": "School of Chemical Engineering and Energy,Zhengzhou University,Zhengzhou,,China"
            },
            {
                "name": "LUO Ting-liang",
                "org": "School of Chemical Engineering and Energy,Zhengzhou University,Zhengzhou,,China"
            }
        ],
        "venue": "Higher Education of Sciences",
        "year": 2012
    },
    "ytyQFRKs": {
        "id": "ytyQFRKs",
        "title": "Clinical study of uroflow rate-EMG on patients with chronic prostatitis",
        "abstract": "【Objective】To investigate the effects of the uroflow rate-EMG in chronic prostatitis.【Methods】128 patients with chronic prostatitis and 30 normal persons were both examined by laborie urodynamic system. The Qmax,Qave,TL value and EMG lag Time were used to explain the Uroflow Rate-urethral sphincter EMG.【Results】The Qmax,Qave and TL value in CP group were significantly lower than those in normal contrast group (P< 0.05); 107 cases had abnormal urethral sphincter EMG in the 128 cases patients (83.6%),and 7 cases had abnormal EMG lag Time (5.5%). There was a positive correlation between TL value and Qmax (r =0.864,P <0.001),and there was a negative corelation between TL value and NIH-CPSI (r =-0.762,P <0.001).【Conclusions】The uroflow rate-EMG technique is a noninvasive,simple,effective method for evaluating lower urinary tract obstruction,and it would play an important role in diagnosis of chronic prostatitis and is useful for clinical practice.",
        "keywords": [
            "uroflow rate",
            "prostatitis",
            "EMG"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Department of Urology,the First Affiliated Hospital,Chongqing Medical University,Chongqing ,P.R.China"
            },
            {
                "name": "LIU Chaodong",
                "org": "Department of Urology,the First Affiliated Hospital,Chongqing Medical University,Chongqing ,P.R.China"
            },
            {
                "name": "MA Xiaoguang",
                "org": "Department of Urology,the First Affiliated Hospital,Chongqing Medical University,Chongqing ,P.R.China"
            },
            {
                "name": "TANG Qubo",
                "org": "Department of Urology,the First Affiliated Hospital,Chongqing Medical University,Chongqing ,P.R.China"
            }
        ],
        "venue": "China Journal of Modern Medicine",
        "year": 2009
    },
    "91OI6bCh": {
        "id": "91OI6bCh",
        "title": "Clinical observation on therapeutic effect of electroacupuncture on chronic prostatitis and detection of urethral sphincter EMG]",
        "abstract": "To observe the clinical therapeutic effect of electroacupuncture for chronic prostatitis and investigate its mechanism.Forty-eight cases were randomly divided into an electroacupuncture group and a western medicine group, 24 cases in each group. The electroacupuncture group was treated by electroacupuncture and Guanyuan (CV 4), Zhongji (CV 3). Ciliao (BL 32) and Huiyang (BL 35) were selected as main acupoints. The western medicine group was treated by oral administration of Sparfloxacin tablets and Prostat tablets. The scores of NIH-CPSI, changes in uroflow rate-urethral sphincter EMG and their therapeutic effects were observed.The total effective rate was 87.5 % in the electroacupuncture group which, was better than 62. 5% in the western medicine group (P(<0. 05). There were significant differences in the scores of NIH-CPSI and Q(max), Q(ave), TL value before and after treatment in the electroacupuncture group (all P<0.05), and with a significant difference in the scores of NIH-CPSI and Q(max). Q(ave), TL value after treatment between the two groups (all P<0.05).Electroacupuncture based on syndrome differentiation has better therapeutic effect on chronic prostatitis than that of routine clinical medicine.",
        "keywords": [
            "prostatitis",
            "electroacupuncture",
            "chronic",
            "electromyography",
            "urinary sphincter"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "1.Department of Urinary Surgery,"
            },
            {
                "name": "Chao-dong Liu",
                "org": "1.Department of Urinary Surgery,"
            },
            {
                "name": "Yan Ding",
                "org": "2.Department of Acupuncture and Moxibustion,The First Affiliated Hospital of Chongqing Medical University,Chongqing ,China"
            },
            {
                "name": "Qu-bo Tang",
                "org": "1.Department of Urinary Surgery,"
            }
        ],
        "venue": "Zhongguo zhen jiu = Chinese acupuncture & moxibustion",
        "year": 2010
    },
    "InN7qMbz": {
        "id": "InN7qMbz",
        "title": "Correlation between levels of NGF and TNF-alpha in category Ⅲ prostatitis",
        "abstract": "【Objective】 To observe the expression and correlation of nerve growth factor(NGF) and tumour necrosis factor-alpha(TNF-α) in category Ⅲ prostatitis,and to investigate its pathogenesis.【Methods】 The levels of NGF and TNF-αin prostatic fluid of category Ⅲ prostatitis patients and healthy men were detected by immunohistochemistry,and the data were analyzed by statistics.【Results】 In patient group the expression of NGF and TNF-αwere significant higher than those in health group(P <0.05),the level of NGF was directly correlated to TNF-α(r =0.42,P <0.01).【Conclusion】 ①NGF and TNF-αmay play important roles in process of the occurrence and development of category Ⅲ prostatitis.②The level of NGF was directly correlated to TNF-αin prostatic fluid.Proinflammatory cytokines(TNF-alpha,et al) and NGF may be in close correlation,which may be an important element in pathogenesis of category Ⅲ prostatitis.",
        "keywords": [
            "TNF-alpha",
            "correlation",
            "proinflammatory cytokines",
            "prostatitis",
            "NGF"
        ],
        "authors": [
            {
                "name": "TANG Qu-bo",
                "org": "The First Affiliated Hospital of Chongqing Medical University,Chongqing ,P.R.China"
            },
            {
                "name": "LIU Chao-dong",
                "org": "The First Affiliated Hospital of Chongqing Medical University,Chongqing ,P.R.China"
            },
            {
                "name": "ZHANG Jie",
                "org": "The First Affiliated Hospital of Chongqing Medical University,Chongqing ,P.R.China"
            }
        ],
        "venue": "China Journal of Modern Medicine",
        "year": 2010
    },
    "TxsZSbaG": {
        "id": "TxsZSbaG",
        "title": "Role of the level of nerve growth Factor and mood disorders in Type Ⅲ prostatitis",
        "abstract": "Objective To observe the changes of mood disorders (depression、anxiety ) and nerve growth factor (NGF) in patient with type Ⅲ prostatitis,and investigate the role of NGF and mood disorders in pathogenesis of type Ⅲ prostatitis.Methods The level of NGF in prostatic secretions of type Ⅲ prostatitis patient and healthy men were detected by immunohistochemistry.Mood disorders of the patients were measured with selfrating anxiety scale (SAS) and selfrating depression scale (SDS).All data was statistically analyzed.Results The expression of NGF and the scores of SAS and SDS in type Ⅲ prostatitis patients were significant higher than that in health group;There was a positive correlation between the expressions of NGF and mood disorders in type Ⅲ prostatitis patients. Conclusion (1)NGF might play an important role in occurrence and development of type Ⅲ prostatitis.(2)There was a close correlation between the expressions of NGF and mood disorders.NGF might be an important mediated substance of mood disorders and affect symptoms of type Ⅲ prostatitis patients.",
        "keywords": [
            "nerve growth factor",
            "emotions",
            "prostatitis"
        ],
        "authors": [
            {
                "name": "Tang Qubo",
                "org": " The first Affiliated Hospital of Chongqing Medical University of Science,Chongqing ,China"
            },
            {
                "name": "Liu Chaodong",
                "org": " The first Affiliated Hospital of Chongqing Medical University of Science,Chongqing ,China"
            },
            {
                "name": "Zhang Jie",
                "org": " The first Affiliated Hospital of Chongqing Medical University of Science,Chongqing ,China"
            }
        ],
        "venue": "Chinese Journal of Andrology",
        "year": 2010
    },
    "r1akk6RW": {
        "id": "r1akk6RW",
        "title": "A survey of the perceived risk for stroke among community residents in western urban China.",
        "abstract": "Persons who perceive their risk for stroke can promote the intervention of stroke risk factors and reduce the risk of stroke occurrence. Our purpose was to assess the knowledge of stroke risk factors and the level of perceived risk for stroke.In 2011, a population-based face-to-face interview survey was conducted in Yuzhong district, Chongqing. A total of 1500 potential participants aged ≥18 years old were selected using a multi-stage sampling method. The knowledge of stroke risk factors and perceived risk for stroke was surveyed.A total of 941 participants completed the questionnaire survey. The respondents' awareness rate of stroke risk factors ranged between 53.3% and 87.2%. The community residents' perceived risk for stroke was only 17.7%. Multiple logistic regression analysis showed that 45-64 years age group, a history of hypertension, hyperlipidemia, heart disease, and stroke were independent predictors of perceived risk for stroke. Perceived risk for stroke increased as the number of risk factors increased (P<0.001). However, even for respondents with three or more risk factors, only 41% perceived themselves to be at risk for stroke.In this population-based survey, few community residents perceived risk for stroke, even among those with multiple stroke risk factors, most did not perceive themselves to be at risk for stroke. Persons with 45-64 years old, a history of hypertension, hyperlipidemia, heart disease or stroke were more likely to perceive risk for stroke. The awareness of the risk for stroke has yet to be enhanced among community residents.",
        "keywords": [],
        "authors": [
            {
                "name": "Juan Yang",
                "org": "Department of Neurology, the Second Affiliated Hospital, Chongqing Medical University, Chongqing, China."
            },
            {
                "name": "Min Zheng",
                "org": ""
            },
            {
                "name": "Shuqun Chen",
                "org": ""
            },
            {
                "name": "Shu Ou",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Ni Wang",
                "org": ""
            },
            {
                "name": "Yingying Cao",
                "org": ""
            },
            {
                "name": "Qiaoqiao Miao",
                "org": ""
            },
            {
                "name": "Xingxiu Zhang",
                "org": ""
            },
            {
                "name": "Ling Hao",
                "org": ""
            },
            {
                "name": "Jinhe Lou",
                "org": ""
            },
            {
                "name": "Huijuan Guo",
                "org": ""
            },
            {
                "name": "Nan Li",
                "org": ""
            },
            {
                "name": "Jian Wang",
                "org": ""
            }
        ],
        "venue": "PloS one",
        "year": 2013
    },
    "ud0H0y6j": {
        "id": "ud0H0y6j",
        "title": "Survey on stroke warning signs and awareness of emergency call for stroke symptoms among community residents in Yuzhong District,Chongqing",
        "abstract": "Objective To investigate how much community residents know for stroke warning signs and react appropriately to make an emergency call(120,in China) when encountering hypothetical stroke-related scenarios in Yuzhong district in Chongqing,China,and to analyze the relationship between their knowledge of stroke warning signs and awareness of emergency call.Methods Multi-stage sampling was used and 1 500 households were selected in 3 subdistricts of Yuzhong district,and one member of each household was chosen to join the survey.A face to face investigation was conducted by trained interviewers.Results A total of 941 participants completed the survey.Respondents' awareness rate of the stroke warning signs was 32.6%-75.6%,and only 16.8% respondents had knowledge of all 5 stroke warning signs.The ratio of calling 120 for a variety of stroke warning signs was 27.1%-42.9%,and only 17.1% respondents reported that they would call 120 for all 5 stroke warning signs.Knowledge of stroke warning signs was significantly correlated with awareness of calling 120(OR 1.96-3.34),but even among those with knowledge of all 5 stroke warning signs,only 33.5%(95%CI,26.2-40.9) of them would call 120.Conclusion The community residents have low knowledge level of stroke warning signs and poor awareness of calling the emergency number 120 for stroke symptoms in Yuzhong district in Chongqing.",
        "keywords": [
            "stroke",
            "knowledge",
            "warning signs",
            "emergency"
        ],
        "authors": [
            {
                "name": "Yang Juan",
                "org": "Department of Neurology,Second Affiliated Hospital,Chongqing Medical University,Chongqing,,China"
            },
            {
                "name": "Wang Jian",
                "org": "Department of Neurology,Second Affiliated Hospital,Chongqing Medical University,Chongqing,,China"
            },
            {
                "name": "Ou Shu",
                "org": "Department of Neurology,Second Affiliated Hospital,Chongqing Medical University,Chongqing,,China"
            },
            {
                "name": "Zhang Jie",
                "org": "Department of Neurology,Second Affiliated Hospital,Chongqing Medical University,Chongqing,,China"
            },
            {
                "name": "Wang Ni",
                "org": "Department of Neurology,Second Affiliated Hospital,Chongqing Medical University,Chongqing,,China"
            },
            {
                "name": "Cao Yingying",
                "org": "Department of Neurology,Second Affiliated Hospital,Chongqing Medical University,Chongqing,,China"
            },
            {
                "name": "Miao Qiaoqiao",
                "org": "Department of Neurology,Second Affiliated Hospital,Chongqing Medical University,Chongqing,,China"
            },
            {
                "name": "Zhang Xingxiu",
                "org": "Department of Neurology,Second Affiliated Hospital,Chongqing Medical University,Chongqing,,China"
            },
            {
                "name": "Hao Ling",
                "org": "Department of Neurology,Second Affiliated Hospital,Chongqing Medical University,Chongqing,,China"
            },
            {
                "name": "Lou Jinhe",
                "org": "Department of Neurology,Second Affiliated Hospital,Chongqing Medical University,Chongqing,,China"
            },
            {
                "name": "Guo Huijuan",
                "org": "Department of Neurology,Second Affiliated Hospital,Chongqing Medical University,Chongqing,,China"
            },
            {
                "name": "Li Nan",
                "org": "Department of Neurology,Second Affiliated Hospital,Chongqing Medical University,Chongqing,,China"
            }
        ],
        "venue": "Journal of Third Military Medical University",
        "year": 2013
    },
    "KNsO5zMZ": {
        "id": "KNsO5zMZ",
        "title": "Prevention and treatment capabilities for stroke in general practitioners and nurses in urban communities in Chongqing",
        "abstract": "Objective To investigate the prevention and treatment capabilities of stroke among general practitioners and nurses in urban communities,Chongqing.Methods Self-designed questionnaire was carried out with a close-exam in 500 general practitioners and nurses working in the community health service in Chongqing.Results There were 331 valid questionnaires and the valid returned rate was 66.2%.Of the 331 respondents,40.7% of general practitioners and 37.5% general nurses knew the clinical guidelines for acute stroke management and secondary stroke prevention,and 51.9% of general practitioners and 37.5% of general nurses reported that they had the capability of managing patient with stroke.The correct rate of answering questions about stroke assessment and management was 24.4%,and the correct rate of secondary stroke prevention was 37.5%.For the total score of stroke prevention and treatment,there were significant differences among the community medical staffs with different specialty before working in the community health service and whether they had received the general practitioner training(P<0.05).Conclusion The knowledge level of stroke of Chongqing general practitioners and nurses is low,which needs to be improved.",
        "keywords": [
            "general practitioner",
            "stroke",
            "general nurse",
            "investigation"
        ],
        "authors": [
            {
                "name": "Zhang Jie",
                "org": "Department of Neurology,Second Affiliated Hospital,Chongqing Medical University,Chongqing,,China"
            },
            {
                "name": "Yang Juan",
                "org": "Department of Neurology,Second Affiliated Hospital,Chongqing Medical University,Chongqing,,China"
            },
            {
                "name": "Wang Jian",
                "org": "Department of Neurology,Second Affiliated Hospital,Chongqing Medical University,Chongqing,,China"
            }
        ],
        "venue": "Journal of Third Military Medical University",
        "year": 2013
    },
    "YUozjZAN": {
        "id": "YUozjZAN",
        "title": "Awareness of stroke risk factors and perceived risk for developing stroke among inpatients with stroke risk factors",
        "abstract": "Objective To investigate the knowledge of stroke risk factors,perceived risk for developing stroke and stroke prevention among patients with stroke risk factors in Department of Neurology.Methods From January to August 2012,face to face interviews were carried out among 500 patients with stroke risk factors by using self-designed questionnaire in Department of Neurology,the Second Affiliated Hospital of Chongqing Medical University.They were asked to answer: \"what were stroke risk factors \",\"whether they would suffer from stroke\"and\"how to prevent stroke\".Multivariate logistic regression was adopted to analyze the factors.Results Four hundred and sixty-seven patients completed the questionnaire.Of the 467 respondents,40.7% of them knew at least one risk factor of stroke,and 15.5% knew more than 3 risk factors.The highest proportion in the response to stroke risk factors were hypertension(39.4%),hyperlipidemia(17.1%) and diabetes(14.6%).Patients of 44.8% were aware of their own risks of stroke.Multivariate logistic regression analysis revealed that stroke was independently associated with education,hyperlipidemia,heart disease,previous history of stroke and the awareness of their own risks of stroke.Patients of 55.2% believed that stroke could be prevented.The most mentioned preventive measures for stroke were reasonable diet(29.3%),appropriate exercise(28.5%),and avoidance of emotion agitation and fall(18.4%).Conclusion Patients with high risk of stroke in Department of Neurology are often unable to identify risk factors of stroke,do not perceive themselves to be at risk to stroke,and are lack of awareness of the stroke preventive measures.It is necessary to strengthen health education to improve their level of awareness of stroke prevention.",
        "keywords": [
            "stroke",
            "stroke risk",
            "risk factors",
            "stroke prevention"
        ],
        "authors": [
            {
                "name": "Cao Yingying",
                "org": "Department of Neurology,Second Affiliated Hospital,Chongqing Medical University,Chongqing,,China"
            },
            {
                "name": "Wang Jian",
                "org": "Department of Neurology,Second Affiliated Hospital,Chongqing Medical University,Chongqing,,China"
            },
            {
                "name": "Yang Juan",
                "org": "Department of Neurology,Second Affiliated Hospital,Chongqing Medical University,Chongqing,,China"
            },
            {
                "name": "Zhang Jie",
                "org": "Department of Neurology,Second Affiliated Hospital,Chongqing Medical University,Chongqing,,China"
            },
            {
                "name": "Wang Ni",
                "org": "Department of Neurology,Second Affiliated Hospital,Chongqing Medical University,Chongqing,,China"
            },
            {
                "name": "Gao Pan",
                "org": "Department of Neurology,Second Affiliated Hospital,Chongqing Medical University,Chongqing,,China"
            }
        ],
        "venue": "Journal of Third Military Medical University",
        "year": 2013
    },
    "dU2RQ2ib": {
        "id": "dU2RQ2ib",
        "title": "Performance of MLC-STBC Using 8PSK Modulation in Rayleigh Fading Channels",
        "abstract": "In this paper,multilevel coding(MLC)based on the novel distance metric with 8PSK modulation in the Rayleigh fading channels is proposed,and at the same time,the characteristics of space-time coding are analyzed.According to the novel distance measure,a MLC with parallel decoding of levels(PDL)system is constructed with good performance in the first modulation.The second simulation indicates that the concatenation scheme combining MLC and STBC according to the new distances metric rules to design the multilevel coding using 8PSK mapping in Rayleigh fading channels can obtain a fairly ideal system gain.",
        "keywords": [
            "STBC",
            "new distance metric",
            "MLC",
            "PDL"
        ],
        "authors": [
            {
                "name": "WANG Xiangjiao",
                "org": "School of Electronics and Information,Northwestern Polytechnical University,Xi'an Shanxi ,Cina"
            },
            {
                "name": "ZHANG Jie",
                "org": "School of Electronics and Information,Northwestern Polytechnical University,Xi'an Shanxi ,Cina"
            }
        ],
        "venue": "Information Security and Communications Privacy",
        "year": 2007
    },
    "D4P4c9p6": {
        "id": "D4P4c9p6",
        "title": "The Reliability Application Study of Supervisory Circuits ADM706",
        "abstract": "The supervisory circuits ADM706 produced by ADI have the characteristics of many function, low power, simple periphery circuits, applied widespread. But the tradition circuits exposure many hidden trouble. For improving the reliability of system, we must be study the reliability of system. After test and analysis, we designed the optimized circuits. To compared with the tradition circuits, the circuits' stability and reliability can be increased remarkably.",
        "keywords": [
            "reliability application",
            "ADM706",
            "WDT"
        ],
        "authors": [
            {
                "name": "JIA YuTao",
                "org": "Northwestern Polytechnical University, Xi'an , China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Northwestern Polytechnical University, Xi'an , China"
            },
            {
                "name": "ZHAO Kai",
                "org": "Northwestern Polytechnical University, Xi'an , China"
            }
        ],
        "venue": "China Information Security",
        "year": 2007
    },
    "jQoAgYyT": {
        "id": "jQoAgYyT",
        "title": "The Research and Implementation of IDS Based on the Intelligent Agent",
        "abstract": "We present an agent-based infrastructure for IDS which could solve the problems confronted in the development of DIDS, accomplish the design and implementation of a prototype-AIAD-IDS. The results of the test prove the feasibility of our framework.",
        "keywords": [
            "IDS",
            "AIAD-IDS",
            "MAS"
        ],
        "authors": [
            {
                "name": "LU Wei",
                "org": "College of Software and Microelectronics, Northwestern Polytechnical University, Xi'an , China"
            },
            {
                "name": "ZHANG Jie",
                "org": "College of Software and Microelectronics, Northwestern Polytechnical University, Xi'an , China"
            },
            {
                "name": "ZHANG Peng",
                "org": " (2Northwest Institute of Mechanical & Electrical Engineering, Xianyang , China"
            }
        ],
        "venue": "China Information Security",
        "year": 2007
    },
    "z3BvRaJb": {
        "id": "z3BvRaJb",
        "title": "An Improved MSUSIC Algorithm for Enhancing the DOA Estimation of Array Antenna",
        "abstract": "The classical MUSIC algorithm is based on the model of uncorrelated signals in array signal processing, it will be ineffective for both the coherent multi-path signals and adjacent signals with small SNR. Making use of the excellent performance characteristic of root-music algorithm in small sample space, this paper brings forward a modified root-music algorithm based on rebuilding data covariance matrix by deduction to enhance the spectrum resolving power of both coherent multi-path signals and adjacent signals with lower SNR. The computer simulation verifies that it is effective,and its spectrum resolving power is obviously improved compared to modified MUSIC algorithm.",
        "keywords": [
            "DOA estimation",
            "Data covariance",
            "Coherence multi-path",
            "Spectrum resolving power"
        ],
        "authors": [
            {
                "name": "YUAN Feng",
                "org": "College of Electronics and Information, Northwestern Polytechnical University, Xi'an Shanxi , China; 71 Unit of 91960 Army of People's Liberation Army of China, Shantou Guangdong , China"
            },
            {
                "name": "ZHANG Jie",
                "org": "College of Electronics and Information, Northwestern Polytechnical University, Xi'an Shanxi , China"
            }
        ],
        "venue": "Computer Simulation",
        "year": 2008
    },
    "pP9Mpkud": {
        "id": "pP9Mpkud",
        "title": "Research on GNSS Receiver Tracking Loop Using Inertial Velocity",
        "abstract": "Global Navigation Satellite System and Inertial Navigation System both are one of the most universal adopted methods in the application of navigation in the world.The combined navigation combined the two system by using the strong noncomparability and complement of them,which made it possible to use the advantages and avoid the disadvantages of the two system.This paper analyze the performance of GNSS receiver tracking loop between with and without velocity aid,by the method of theoretic derivation and simulation.The results demonstrated predominances of the tracking loop aided by the inertial velocity,has been imploved apparently and laid the theory foundation for the engineering application of GNSS/INS combination system.",
        "keywords": [
            "GNSS /INS combined navigation",
            "tracking loop",
            "velocity aid"
        ],
        "authors": [
            {
                "name": "YU Zhong-qing",
                "org": "Electronic Information Institute,Northwestern Polytechnical University,Xi'an ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Electronic Information Institute,Northwestern Polytechnical University,Xi'an ,China"
            },
            {
                "name": "GONG Cheng",
                "org": "China Aviation Radio Electronic Research Institute,Shanghai ,China"
            }
        ],
        "venue": "Wireless Communication Technology",
        "year": 2008
    },
    "Vi92gq20": {
        "id": "Vi92gq20",
        "title": "Research on V-BLAST Detection Algorithms of MIMO system in Rayleigh Fading Channels",
        "abstract": "The Vertical-BLAST is effective in achieving high data rate in wireless communication.The MMSE detection algorithms can restrain the interference among the information flow and reduce the noise in Rayleigh Slow-Fading Channels.A Symbol by Symbol MMSE-SIC detection algorithm based on its signal model is proposed to enhance the performance of signal error rate(SER) of the systems for Rayleigh Fast-Fading Channels,which combines Multi-variables Statistical Analysis,Successive Interference Cancellation and Optimal Ordering schemes.The computer simulation verifies that SSMMSE-OSIC algorithm and MMSE-OSIC algorithm are effective in improving the SER of their applicable system,and can enhance the bandwidth efficiency.",
        "keywords": [
            "Multi-variable statistical analysis",
            "Vertical-BLAST",
            "Bandwidth efficiency",
            "Symbol by symbol detection"
        ],
        "authors": [
            {
                "name": "YUAN Feng",
                "org": "College of Electronics and Information,Northwestern Polytechnical University,Xi'an Shanxi ,China;71 Unit of 91960 Army of People's Liberation Army of China,Shantou Guangdong,,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "College of Electronics and Information,Northwestern Polytechnical University,Xi'an Shanxi ,China"
            }
        ],
        "venue": "Computer Simulation",
        "year": 2008
    },
    "ZDua1eFB": {
        "id": "ZDua1eFB",
        "title": "Study and Development of Stream Media Recording and Playing in Video Conference System",
        "abstract": "This paper discusses the scheme for implementing the function of recording and playing in video conference system using stream media. In this recording and playing scheme, the stream media is connected to video conference as a virtual terminal, and the conference information is recorded and stored in stream media server. This application shows that by using the broadcast and VOD service module of the stream media server, the video conference, stream media, IPTV and PC customer terminal can be effectively integrated. The technology and methods could fairly promote the integration and development of video conference and IPTV, and thus are of certain practical value.",
        "keywords": [
            "stream media",
            "technology of recording and playing",
            "video conference"
        ],
        "authors": [
            {
                "name": "WEI Feng",
                "org": "Electronics and information college, Northwestern Polytechnical University, Xi’an Shaanxi , China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Electronics and information college, Northwestern Polytechnical University, Xi’an Shaanxi , China"
            },
            {
                "name": "DUAN Hui-qing",
                "org": "Electronics and information college, Northwestern Polytechnical University, Xi’an Shaanxi , China"
            }
        ],
        "venue": "Information Security and Communications Privacy",
        "year": 2009
    },
    "RFDk0oA2": {
        "id": "RFDk0oA2",
        "title": "Study on Application of Detection Technologies in HSDPA MIMO System",
        "abstract": "In the light of HSDPA MIMO systems,a rank-based MIMO detection algorithm of QR decomposition is proposed,and its performance is analyzed.The algorithm is a detection algorithm for the QR decomposition of a higher error rate,and the channel matrix is sorted by columns 2-Norm from small to large value of a second order,thus eliminating the interference of the received signal,reducing the system bit error rate,and improving the system detection performance.The simulation experiment based on HSDPA MIMO 2×2 simulation platform shows that,as compared with traditional QR decomposition algorithm,the QR algorithm based on sorting is significantly improved in system BER performance.",
        "keywords": [
            "MIMO system",
            "zero-forcing detection",
            "bit error rate"
        ],
        "authors": [
            {
                "name": "GONG Zhao-yang",
                "org": "Northwestern Polytechnical University,Xi'an Shaanxi ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Northwestern Polytechnical University,Xi'an Shaanxi ,China"
            },
            {
                "name": "SONG Yan",
                "org": "Northwestern Polytechnical University,Xi'an Shaanxi ,China"
            }
        ],
        "venue": "Information Security and Communications Privacy",
        "year": 2010
    },
    "kIV08i2s": {
        "id": "kIV08i2s",
        "title": "Performance analysis of space time block code in MIMO-OFDM systems",
        "abstract": "MIMO-OFDM system, which is the combination of MIMO and OFDM technology, can live up to a high data transmission rate with reliability through diversity. MIMO-OFDM with STBC has excellent performance against Multi-path effects and frequency selective fading, what's more, the BER and the coding complexity is low. In this paper, a simulation model of MIMO-OFDM system based on STBC is built and transmission performances under different channels are analyzed. The simulation results show that the MIMO-OFDM system based on STBC outperforms other MIMO-OFDM system without STBC in BER performance.",
        "keywords": [
            "mimo-ofdm",
            "diversity reception",
            "frequency selective fading",
            "ber",
            "high data transmission rate",
            "ofdm modulation",
            "stbc",
            "diversity",
            "multipath effects",
            "mimo communication",
            "reliability",
            "space-time block codes",
            "mimo-ofdm systems",
            "space time block code",
            "mimo",
            "bit error rate",
            "mimo ofdm"
        ],
        "authors": [
            {
                "name": "Zhang Jie",
                "org": "Northwestern Polytechnical University(Northwestern Polytechnical University,Northwestern Polytechnical Univ),Xi'an,China"
            },
            {
                "name": "Liu Liang",
                "org": "Northwestern Polytechnical University(Northwestern Polytechnical University,Northwestern Polytechnical Univ),Xi'an,China"
            },
            {
                "name": "Li Jin",
                "org": "Northwestern Polytechnical University(Northwestern Polytechnical University,Northwestern Polytechnical Univ),Xi'an,China"
            }
        ],
        "venue": "Communication Software and Networks",
        "year": 2011
    },
    "I8TaOlEc": {
        "id": "I8TaOlEc",
        "title": "Format Parsing of Programmable Files in Embedded Development System",
        "abstract": "There are a variety of programmable file formats in embedded systems.The paper analyzes embedded executable file(i.e.machine-code file) formats,and compares similarities and differences between the different formats in order to facilitate the development of embedded systems and an understanding of the target system.At last,the hardware device and the target systems of each format are discussed.",
        "keywords": [
            "programmable file",
            "HEX format",
            "embedded system"
        ],
        "authors": [
            {
                "name": "Xu Luhua",
                "org": "School of Electronics and Information,Northwestern Polytechnical University,Xi'an ,China"
            },
            {
                "name": "Dong Xiaowei",
                "org": "Institute of Microelectronics Chinese"
            },
            {
                "name": "Zhang Hao",
                "org": "Institute of Microelectronics Chinese"
            },
            {
                "name": "Zhang Jie",
                "org": "School of Electronics and Information,Northwestern Polytechnical University,Xi'an ,China"
            }
        ],
        "venue": "Microcontrollers & Embedded Systems",
        "year": 2011
    },
    "hphOBtSm": {
        "id": "hphOBtSm",
        "title": "Effect of A/D quantization bits on the anti-jamming performance",
        "abstract": "Digital receiver input SINR has a great impact on acquisition performance.In this paper,theoretical analysis and a large number of simulation are given to analyze the impact of quantization bits on the relative acquisition peak and SINR of navigation signals,and under a given anti-jamming indicator,the required minimum and maximum quantization bits of satellite navigation and anti-jamming system are given in the experiment.A reasonable choice of quantization as a theoretical basis be provided to the navigation anti-jamming system.",
        "keywords": [
            "quantization",
            "acquisition",
            "anti-jamming",
            "output SINR"
        ],
        "authors": [
            {
                "name": "ZHANG Kun",
                "org": "School of Electronics and Information,Northwestern Polytechnical University,Xi'an ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "School of Electronics and Information,Northwestern Polytechnical University,Xi'an ,China"
            },
            {
                "name": "ZHANG Xing",
                "org": "School of Electronics and Information,Northwestern Polytechnical University,Xi'an ,China"
            },
            {
                "name": "REN Song-yu",
                "org": "School of Electronics and Information,Northwestern Polytechnical University,Xi'an ,China"
            }
        ],
        "venue": "Electronic Design Engineering",
        "year": 2012
    },
    "bLzQJ2pL": {
        "id": "bLzQJ2pL",
        "title": "Improved OPAST algorithm and its application in the blind multiuser detection",
        "abstract": "The orthonormal projection approximation and subspace tracking algorithm(OPAST) is introduced.It is a kind of method based on the theory of optimum.It guarantees the orthonormality of the weight matrix at each iteration.Moreover it has a linear complexity like the PAST algorithm and a global convergence property like the natural power(NP) method.However it can appear suddenly increase ber phenomenon after a certain numbern of iteration,when it is applied to the blind multiuser detection.It lead to decline in the performance.In order to solve this problem,this paper puts forward a method,and prove it is effective through the results of the simulation.",
        "keywords": [
            "BER",
            "OPAST algorithm",
            "adaptive algorithm",
            "blind multiuser detection"
        ],
        "authors": [
            {
                "name": "WANG Hao",
                "org": "School of Electronics and Information,Northwestern Polytechnical University,Xi'an ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "School of Electronics and Information,Northwestern Polytechnical University,Xi'an ,China"
            },
            {
                "name": "REN Song-yu",
                "org": "School of Electronics and Information,Northwestern Polytechnical University,Xi'an ,China"
            }
        ],
        "venue": "Electronic Design Engineering",
        "year": 2012
    },
    "fFsQAyGj": {
        "id": "fFsQAyGj",
        "title": "Relationship between the decrease of methylation of cyclinD1 and colorectal carcinoma",
        "abstract": "Objective To study the significance and the correlation between the change of the methylation status of cyclinD1 gene in promoter region and colorectal tumorigenesis.Methods Methylation-specific PCR was used to detect the methylation status of cyclinD1 gene,and the pathological characteristics were analyzed.Results For the level of methylation of cyclinD1,there was a descending tendency in colorectal carcinogenisis,compared with normal mucosa epithelium,and there was a significant difference in adjacent tissue,adenoma and carcinoma(P<0.01).There was an obviously inverse correlation between abnormal methylation of cyclinD1 and its expression.The level of mythylation of cyclinD1 was closely correlated with the degree of differentiation,the depth of infiltration and the metastasis of lymph node(P<0.01).Conclusion The decrease of methylation of cyclinD1 lead to overexpression of cyclinD1,which play an important role in colorectal carcinogenesis,and it might be a useful molecular marker in early diagnosis,malignant judgement and prognosis of colorectal carcinoma.",
        "keywords": [
            "colorectal carcinoma",
            "DNA methylation",
            "cyclinD1 gene"
        ],
        "authors": [
            {
                "name": "CUI Jing",
                "org": "Department of Pathology,Xinxiang Medical College,Xinxiang,"
            },
            {
                "name": "ZHANG Jing-hang",
                "org": "Department of Pathology,Xinxiang Medical College,Xinxiang,"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Pathology,Xinxiang Medical College,Xinxiang,"
            }
        ],
        "venue": "Journal of Xinxiang Medical College",
        "year": 2006
    },
    "JKNLM1a3": {
        "id": "JKNLM1a3",
        "title": "Expressions and significance of △Np63 mRNA in esophageal squamous cell carcinoma",
        "abstract": "Objective To investigate the expression and significance of delta p63(△Np63),a novel member of p53 gene family,in esophageal squamous cell carcinoma.Methods The expression of △Np63 mRNA in 50 cases of esophageal carcinoma and 50 cases of normal esophageal mucoma were detected by reverse transcription-polymerase chain reaction(RT-PCR).And analyzed the relation among clinical patho-index of esophageal squamous cell carcinoma.Results The positive expression rate(74.0%) and relative content(1.036±0.157)of △Np63 mRNA in esophageal squamous cell carcinoma were significantly higher than in normal esophageal mucoma(40.0%,0.954±0.110).The positive expression rate and relative content of △Np63 mRNA in esophageal squamous cell carcinoma were correlated with degrees of differentiation and lymph node metastasis(P<0.05).Conclusion Over expression of △Np63 gene may be relation with invasion and lymph node metastasis in esophageal squamous cell carcinoma.",
        "keywords": [
            "reverse transcription-polymerase chain reaction",
            "△Np63",
            "esophageal squamous cell carcinoma"
        ],
        "authors": [
            {
                "name": "LI Na",
                "org": "Department of Pathology,Xinxiang Medical College,Xinxiang ,China;Department of Pathology,College of Basic Medical Sciences,,Zhengzhou University,Henan Key Laboratory of Tumor Pathology,Zhengzhou ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Pathology,Xinxiang Medical College,Xinxiang ,China"
            },
            {
                "name": "JIAO Yun-juan",
                "org": "Department of Pathology,Xinxiang Medical College,Xinxiang ,China"
            }
        ],
        "venue": "Journal of Xinxiang Medical College",
        "year": 2007
    },
    "qrdC81yB": {
        "id": "qrdC81yB",
        "title": "Significance of expression of FEZ1 gene in esophagealsquamous cell carcinoma",
        "abstract": "Objective To investigate expression of tumor suppressor gene FEZ1 and relationship between FEZ1 expression and clinicopathological features of esophageal squamous cell carcinoma.Methods The expression of FEZ1 mRNA in 50 cases of esophageal carcinoma and 50 cases of normal esophageal mucoma were detected by in situ hybridization(ISH).The expression of protein in esophageal carcinoma cell lines,EC-1 with low differentiation and EC9706 with high differentiation,was detected by Western blot.Results The positive expression rate of FEZ1 mRNA in esophageal squamous cell carcinoma(42.0%) were significantly lower than in normal esophageal mucoma(86.0%)(P=0.000).The positivity of FEZ1 mRNA in esophageal squamous cell carcinoma was related with differentiation(P=0.007) and lymph node metastasis(P=0.013).The expression of protein in low differentiated cell was lower than that in high differentiated cell,but there was no significant difference between them(P=0.062).Conclusion Missing expression of FEZ1 gene may be relation with differentiation and metastasis in esophageal squamous cell carcinoma.",
        "keywords": [
            "western blot",
            "esophageal squamous cell carcinoma",
            "in situ hybridization",
            "FEZ1"
        ],
        "authors": [
            {
                "name": "LI Na",
                "org": "Department of Pathology,Xinxiang Medical College,Xinxiang ,China;Department of Pathology,the First Affiliated Hospital,Zhengzhou University,Henan Key Laboratory of Tumor Pathology,Zhengzhou ,China"
            },
            {
                "name": "WANG Hong-xing",
                "org": "Department of Clinical Immunology,Xinxiang Medical College,Xinxiang ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Pathology,Xinxiang Medical College,Xinxiang ,China"
            }
        ],
        "venue": "Journal of Xinxiang Medical College",
        "year": 2008
    },
    "QQCgUkVS": {
        "id": "QQCgUkVS",
        "title": "Expressions of Livin and Smac in benign and malignant breast lesions",
        "abstract": "Aim:To investigate the expressions of Livin and Smac in breast benign and malignant lesions.Methods:A total of 152 samples including 18 cases of invasive breast distal normal breast tissue,41 cases of benign breast hyperplasia,20 cases of intraductal breast cancer,91 cases with breast ductal carcinoma(61 cases with lymph node metastasis,30 cases without lymph node metastasis) were collected to detect Livin and Smac proteins using immunohistochemical method and tissue microarrays analysis.Results:①The positive rates of Livin protein in normal tissue,benign breast hyperplasia,intradactal breast cancer and breast ductal carcinoma tissue were 11.1%(2/18),43.9%(18/41),80.0%(16/20),and 90.1%(82/91),respeetively increased by turn(χ2=60.800,P<0.05).The positive rates of Smac protein in tissues mentioned above were 83.3%(15/18),78.0%(32/41),90.0%(18/20),and 50.5%(46/91),respectively.There were significantly differences in the positive rate of Smac in the 4 groups(χ2=19.646,P<0.05).Smac expression was not correlated with patient's age,the size of the tumor,ER,and PR(P>0.05),but correlated with lymph node metastasis(χ2=32.772,P<0.05).Conclusion:Livin and Smac might play an important role in the carcinogenesis and progression in breast carcinoma.",
        "keywords": [
            "breast carcinoma",
            "Livin",
            "Smac"
        ],
        "authors": [
            {
                "name": "ZHANG Xia",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang ;Zhengzhou Univercity Press,Zhengzhou "
            },
            {
                "name": "QIAN Xinlai",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "CUI Jing",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "LI Xinqiang",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "LI Yongzhen",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "ZHAO Jie",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            }
        ],
        "venue": "Journal of Zhengzhou University(Medical Sciences)",
        "year": 2009
    },
    "HlXuA8Vx": {
        "id": "HlXuA8Vx",
        "title": "Expression of HLA-DR antigen in gastric carcinoma",
        "abstract": "ObjectiveTo investigate expression of HLA-DR antigen in gastric carcinoma and to provide basis for immunotherapy and prognosis of gastric carcinoma.MethodsImmunohistochemical staining(SP method) and reverse transcription-polymerase chain reaction(RT-PCR) were used to detect HLA-DR protein and mRNA expression in 36 cases of gastric carcinoma and 36 cases of normal gastric epithelia.The relationship between HLA-DR expression and clinical pathology of gastric carcinoma was analyzed.ResultsThe positive expression rate of HLA-DR in gastric carcinoma(58.3%) was significantly higher than that in normal gastric epithelia(5.60%,P<0.05),and it could reduce with the degrees of differentiation reduction(P<0.05).The expression of HLA-DR in gastric carcinoma was irrelevant with degrees of differentiation(P>0.05).The positive expression rate of HLA-DR in gastric carcinoma with lymph node metastasis(43.5%) was lower than that in gastric carcinoma with no lymph node metastasis(84.6%,P<0.05).The positive expression rate and relative expression levels of HLA-DR mRNA in gastric carcinoma(52.9%,0.760±0.158) were significantly higher than in normal gastric epithelia(8.30%,0.551±0.027,P<0.05).The expression of HLA-DRα mRNA was irrelevant with degrees of differentiation and depth of imbibition(P>0.05).ConclusionThe expression of HLA-DR may be associated with the carcinogenesis and development of gastric carcinoma,it can be used for judging its biological behavior.",
        "keywords": [
            "human leukocyte antigen-DR",
            "gastric carcinoma",
            "immunohistochemistry",
            "reverse transcriptase polymerase chain reaction"
        ],
        "authors": [
            {
                "name": "WANG Hong-xing",
                "org": "Department of Clinical Immunology,Xinxiang Medical College,Xinxiang ,China"
            },
            {
                "name": "LI Na",
                "org": "Department of Pathology,Xinxiang Medical College,Xinxiang ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Pathology,Xinxiang Medical College,Xinxiang ,China"
            }
        ],
        "venue": "Journal of Xinxiang Medical College",
        "year": 2009
    },
    "i6ezFvlh": {
        "id": "i6ezFvlh",
        "title": "Detection and typing of human papillomaviruses in breast benign and malignant lesions",
        "abstract": "Aim:To investigate the infection rate and typing of human papillomaviruses(HPVs) in breast benign and malignant lesions.Methods:A total of 73 fresh breast carcinoma tissue and 84 fresh breast benign lesions were collected and subjected to detect and type HPVs by PCR assay.Results:In 73 breast carcinoma tissue,the positive rate of HPV16 was 76.7%(56/73),that of high risk-HPVs(HPV16 and 59) was 76.7%(56/73),including 20 cases with HPV16 infection alone,6 cases with HPV16 and 59 mixed infection,28 cases with HPV16 and 6/11 mixed infection,and 2 cases with multiple infection(HPV16 with HPV59 and HPV6/11).In 84 breast benign lesions,the positive rate of HPV16 was 48.8%(41/84),that of high risk-HPVs was 51.2%(43/84),including 15 cases with HPV16 infection alone,2 cases with HPV59 infection alone,2 cases with HPV6/11 infection alone,24 cases with HPV16 and 6/11 mixed infection,2 cases with multiple infections(HPV16 with HPV59 and HPV6/11).HPV18,31,33,52,and 58 were not found in all breast benign and malignant lesions.There was significant difference in the positive rates of HPV16 and HR-HPVs between breast benign and malignant lesions(χ2 was 12.879,10.921,respectively,P<0.01).The positive rate of HPV16 in invasive ductal carcinoma tissue was 80.6%(43/50),higher than 56.6%(13/23) in invasive lobular carcinoma tissue(χ2=7.663,P<0.01).Conclusion:HPV16 may play an important role in the carcinogenesis of breast carcinoma,and the mixed infection of HPV16 with HPV59 or HPV6/11 should be emphasized in breast carcinoma.",
        "keywords": [
            "breast benign lesion",
            "breast carcinoma",
            "human papillomavirus"
        ],
        "authors": [
            {
                "name": "QIAN Xinlai",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "CUI Jing",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "YE Yaping",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "ZHANG Gang",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "CHANG Haimin",
                "org": "Department of Forensic Clinical Medicine,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "LI Xinqiang",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "HE Guoyang",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "ZHAO Jie",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "ZHU Huifang",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "HAN Fangyi",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "YANG Huilin",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "WANG Xia",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "YUAN Zhiqing",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            }
        ],
        "venue": "Journal of Zhengzhou University(Medical Sciences)",
        "year": 2009
    },
    "QsazNvVf": {
        "id": "QsazNvVf",
        "title": "Expressions of E6 and E7 proteins in HPV16 DNA-positive breast benign and malignant lesions",
        "abstract": "Aim:To investigate the expressions of human papillomavirus 16 type(HPV16) E6 and E7 proteins in HPV16 DNA-positive breast benign and malignant lesions.Methods:A total of 56 HPV16 DNA-positive breast carcinomatissue and 41 breast benign lesions confirmed by PCR were used to detect HPV16 E6 and E7 proteins using Western blotting assay.Results:In 56 HPV16 DNA-positive breast carcinoma tissue,the positive rates of HPV16 E6,E7,and E6/E7 co-expression were 67.9%(38/56),75.0%(42/56),and 57.1%(32/56),respectively,all higher than those of 36.6%(15/41),43.9%(18/41),and 24.4%(10/41),respectively,in 41 HPV16 DNA-positive breast benign lesions(χ2 was 9.34,9.70,10.34,respectively,P<0.01).The HPV16 E6,E7,and E6/E7 co-expression were associated with lymph node metastasis of patients with breast carcinoma(χ2 was 3.88,15.86,9.34,respectively,P<0.05),but not with age or histological classification(P>0.05).Conclusion:HPV16 E6 and E7 proteins may play an important role in the carcinogenesis and progression,and were associated with lymph node metastasis of breast carcinoma.",
        "keywords": [
            "lymph node metastasis",
            "breast carcinoma",
            "early gene 7",
            "early gene 6",
            "human papillomavirus 16 type"
        ],
        "authors": [
            {
                "name": "QIAN Xinlai",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "ZHAO Jie",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "ZHANG Gang",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "CHANG Haimin",
                "org": "Department of Forensic Clinical Medicine,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "LI Xinqiang",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "HE Guoyang",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "YE Yaping",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "ZHU Huifang",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "HAN Fangyi",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "YANG Huilin",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "WANG Xia",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "YUAN Zhiqing",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            }
        ],
        "venue": "Journal of Zhengzhou University(Medical Sciences)",
        "year": 2009
    },
    "JnD3V6Ja": {
        "id": "JnD3V6Ja",
        "title": "Detection of p53 gene in HPV16 E6 protein-positive and-negative breast carcinoma tissue",
        "abstract": "Aim:To investigate the status and expression of p53 gene in human papillomavirus 16 type(HPV16) E6 protein-positive(E6+) and-negative(E6-) breast carcinoma tissue.Methods:56 HPV16 DNA-positive breast carcinoma,including 38 cases with HPV16 E6+ and 18 cases with HPV16 E6-certified by Western blotting assay,were subjected to detect p53 DNA in the conserved core domain by PCR and sequencing,p53 mRNA by RT-PCR,and P53 protein by Western blotting assay.Results:The mutation rates of p53 gene in HPV16 E6+ and HPV16 E6-breast carcinoma tissue were 15.8%(6/38) and 72.2%(13/18),respectively,there was significant difference(χ2=17.352,P<0.001).Almost all mutations were present in exon 5,exon 6,exon 7,and exon 8.The mutations of 248 and 273 codons revealed higher frequency.One mutation was a nonsense mutation,one was a samesense mutation,whereas all other were missense mutations.55 cases expressed p53 mRNA.The positive rate of P53 protein in HPV16 E6+/wtp53 breast carcinoma tissue was 9.4%(3/32),lower than 5/6 in HPV16 E6+/mtp53 breast carcinoma tissue and 4/5 in E6-/wtp53 breast carcinoma tissue(P<0.01).Conclusion:The gene mutation may be the main mechanism for inactivation of p53 in HPV16 E6-breast carcinoma,but not for HPV16 E6-breast carcinoma.HPV16 E6 may play an important role in the carcinogenesis and progression of breast carcinoma by degrading wtP53 protein.",
        "keywords": [
            "breast carcinoma",
            "gene mutation",
            "p53 gene",
            "early gene 6",
            "human papillomavirus 16 type"
        ],
        "authors": [
            {
                "name": "QIAN Xinlai",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "MENG Yong",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "CHANG Haimin",
                "org": "Department of Forensic Clinical Medicine,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "HE Guoyang",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "LI Xinqiang",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "ZHAO Jie",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "ZHU Huifang",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "HAN Fangyi",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "YANG Huilin",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "WANG Xia",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "YE Yaping",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "YUAN Zhiqing",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            }
        ],
        "venue": "Journal of Zhengzhou University(Medical Sciences)",
        "year": 2009
    },
    "DCrozG72": {
        "id": "DCrozG72",
        "title": "Expression of cell cycle control-related gene proteins in HPV16 E7 protein-positive and-negative breast carcinoma tissue",
        "abstract": "Aim:To investigate the expressions of cell cycle control-related gene proteins in human papillomavirus 16 type(HPV16) E7 protein-positive(E7+) and-negative(E7-) breast carcinoma tissue.Methods:A total of 56 HPV16 DNA-positive breast carcinoma specimens confirmed by PCR,including 42 HPV16 E7+ and 14 HPV16 E7-,were used to examine the expressions of Cyclin A,Cyclin D,Cyclin E,P21 and P27 by Western blotting assay.Results:The positive rates of Cyclin A,Cyclin D,Cyclin E,P21,and P27 in HPV16 E7+ breast carcinoma tissue were 97.6%(41/42),76.2%(32/42),92.9%(39/42),9.5%(4/42),and 40.5%(17/42),respectively,while those in HPV16 E7-breast carcinoma tissue were 64.3%(9/14),78.6%(11/14),57.1%(8/14),50.0%(7/14) and 42.9%(6/14),respectively.Compared with those in the HPV16 E7-breast carcinoma tissue,the expressions of Cyclin A and Cyclin E were up-regulated significantly(χ2 was 12.196,9.929,respectively,P<0.01),the expression of P21 was down-regulated(χ2=10.898,P<0.01),but the expressions of Cyclin D and P27 had not obvious changes(χ2 was 0.033,0.025,respectively,P>0.05) in HPV16 E7+ breast carcinoma tissue.Conclusion:HPV16 E7 may play an important role in the carcinogenesis and progression of breast carcinoma by up-regulating the expressions of Cyclin A and Cyclin E,and down-regulating the expression of P21.",
        "keywords": [
            "P21",
            "cyclin",
            "breast carcinoma",
            "early gene 7",
            "P27",
            "human papillomavirus 16 type"
        ],
        "authors": [
            {
                "name": "QIAN Xinlai",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "YE Yaping",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "LI Xinqiang",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "ZHU Huifang",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "GAO Yong",
                "org": "Department of Surgery,Anyang People's Hospital,Anyang "
            },
            {
                "name": "HAN Fangyi",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "YANG Huilin",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "WANG Xia",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "HE Guoyang",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "CHANG Haimin",
                "org": "Department of Forensic Clinical Medicine,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "ZHAO Jie",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "YUAN Zhiqing",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            }
        ],
        "venue": "Journal of Zhengzhou University(Medical Sciences)",
        "year": 2009
    },
    "WmFKP9mK": {
        "id": "WmFKP9mK",
        "title": "Detection of P16 protein and methylation status of promoter region of p16 gene in HPV16 E7 protein-positive and-negative breast carcinoma tissue",
        "abstract": "Aim:To investigate the relationship between the expression of P16 protein and methylation status of promoter region of p16 gene in human papillomavirus 16 type(HPV16) E7 protein-positive(E7+) and-negative(E7-) breast carcinoma tissue.Methods:A total of 56 HPV16 DNA-positive breast carcinoma specimens,including 42 HPV16 E7+ and 14 HPV16 E7-breast carcinoma specimens certified by Western blotting assay,were subjected to detect the methylation status of p16 promoter region by methylation-specific polymerase chain reaction(MSP) and P16 protein by Western blotting assay.Results:The methylation rate of p16 promoter region in HPV16 E7+ group was 11.9%(5/42),the positive rate of P16 was 85.7%(36/42),and the expression of P16 was closely associated with the methylation status of p16 promoter region(rp=0.912,P=0.000).The methylation rate of p16 promoter region in HPV16 E7-group was 78.6%(11/14),the positive rate of P16 was 21.4%(3/14),and the expression of P16 was associated with the methylation status of p16 promoter region(rp=0.779,P=0.043).Compared with those(χ2=20.525,P<0.01) in HPV16 E7-group,the methylation rate of p16 promoter region was lower(χ2=17.405,P<0.01) in HPV16 E7+ group(P<0.01).Conclusion:Hypomethylation status may be the foundation of p16 transcription activated by the regulatory feedback in pRb/p16 pathway due to the removal of the Rb repression by E7.",
        "keywords": [
            "methylation",
            "promoter",
            "breast carcinoma",
            "p16 gene",
            "human papillomavirus 16 type"
        ],
        "authors": [
            {
                "name": "LI Xinjuan",
                "org": "Department of Physiology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "CUI Jing",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "ZHU Huifang",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "HAN Fangyi",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "YANG Huilin",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "WANG Xia",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "YE Yaping",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "LI Xinqiang",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "MA Shuai",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "HE Guoyang",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "ZHAO Jie",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "CHANG Haimin",
                "org": "Department of Forensic Clinical Medicine,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "QIAN Xinlai",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            }
        ],
        "venue": "Journal of Zhengzhou University(Medical Sciences)",
        "year": 2009
    },
    "v0ohvzTL": {
        "id": "v0ohvzTL",
        "title": "Expressions of Rb and P16 proteins in HPV16 E7 protein-positive and-negative breast carcinoma tissue",
        "abstract": "Aim:To investigate the expression and significance of Rb and P16 proteins in human papillomavirus 16 type(HPV16) E7 protein-positive(E7+) and-negative(E7-) breast carcinoma tissues.Methods:A total of 56 HPV16 DNA-positive breast carcinoma specimens confirmed by PCR,including 42 HPV16 E7+ and 14 HPV16 E7-breast carcinoma specimens certified by Western blotting assay,were subjected to detect Rb and P16 proteins by Western blotting assay.Results:The positive rates of Rb in HPV16 E7+ and HPV16 E7-breast carcinoma tissues were 9.5%(4/42) and 50.0%(7/14),respectively,while the positive rates of P16 were 85.7%(36/42) and 21.4%(3/14),respectively.There were significant differences in the expressions of P16 and Rb between HPV16 E7+ and HPV16 E7-tissue(χ2 was 20.525,10.898,respectively,P<0.01).The expression of P16 was also associated with that of Rb in HPV16 E7+ tissue(rp=0.792,P=0.003),but not in HPV16 E7-breast carcinoma tissue(P=0.182).Conclusion:The HPV16 E7 may play an important role in the carcinogenesis and progression of breast carcinoma by degrading Rb protein and up-regulating P16 protein expression.",
        "keywords": [
            "Rb",
            "p16",
            "breast carcinoma",
            "early gene 7",
            "human papillomavirus 16 type"
        ],
        "authors": [
            {
                "name": "YE Yaping",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "QIAN Xinlai",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "HE Guoyang",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "CHANG Haimin",
                "org": "Department of Forensic Clinical Medicine,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "ZHU Huifang",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "HAN Fangyi",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "YANG Huilin",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "WANG Xia",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "ZHAO Jie",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "LI Xinqiang",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Pathology,Xinxiang Medical University,Xinxiang "
            }
        ],
        "venue": "Journal of Zhengzhou University(Medical Sciences)",
        "year": 2009
    },
    "T8Xn1Ap0": {
        "id": "T8Xn1Ap0",
        "title": "Effect of the inhibitor of phosphoinositide 3-kinase /protein kinase B on the growth of human brain glioma U251 cell line",
        "abstract": "Objective To investigate the effect of LY294002 for the proliferation of U251 cell line as a specific inhibitor of phosphoinositide 3-kinase /protein kinase B ( PI3K /PKB). Methods The phosphorylated protein B ( P-PKB) expression of U251 cell interfered with LY294002 were detected by immunocytochemistry. The inhibition ratio of U251 cell proliferation interfered with LY294002( 5,10,20,40 μmol·L -1 ) were detected by methyl thiazolyl tetrazolium after intervention 24,48,72 hours. Results The growth of U251 cell was inhibited by LY294002 in dose-dependent and time-dependent way. Compared to the control group,the P-PKB expression in groups interfered with different dose LY294002 decreased( P < 0. 05). With the increase of the dose of the LY294002,the inhibition ratio of U251 cell proliferation increased,and there was significant difference( P < 0. 01). Conclusion LY294002 can inhibit the growth of U251 cell of human brain glioma. The inhibition of LY294002 for the expression of P-PKB may play an important role in the suppression of cell proliferation.",
        "keywords": [
            "protein kinase B",
            "brain glioma",
            "cell line",
            "LY294002"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Department of Pathology,Xinxiang Medical College,Xinxiang ,China"
            },
            {
                "name": "JIAO Yun-juan",
                "org": "Department of Pathology,Xinxiang Medical College,Xinxiang ,China"
            },
            {
                "name": "ZHU Guo-yong",
                "org": " Youth League Committee,Xinxiang Medical College,Xinxiang ,China"
            },
            {
                "name": "ZHANG Hong-tao",
                "org": " Youth League Committee,Xinxiang Medical College,Xinxiang ,China"
            }
        ],
        "venue": "Journal of Xinxiang Medical College",
        "year": 2010
    },
    "DZtCWf1T": {
        "id": "DZtCWf1T",
        "title": "Detection and analysis of Ets-1 and c-Met mRNA in esophageal squamous cell carcinoma",
        "abstract": "Objective To investigate the expression and significance of Ets-1 and c-Met mRNA in different esophageal lesions.Methods Sixty-two samples of esophageal squamous cell carcinoma(ESCC) tissues,thirty-one samples of adjacent atypical hyperplastic epithelia and sixty-two samples of normal esophageal epithelia were collected in Anyang cancer hospital.The expression of Ets-1 and c-Met mRNA was detected with in situ hybridization.Results The expression levels of Ets-1 and c-Met mRNA in ESCC tissues,adjacent atypical hyperplasia epithelia and normal esophageal epithelia had significant differences among them(P<0.01).For ESCC,the expression levels of Ets-1 and c-Met mRNA were significantly related to the depth of invasion and lymph node metastasis(P<0.05).For ESCC patients,the expression rates of Ets-1 and c-Met mRNA were not correlated with age or gender(P>0.05).The expression of Ets-1 mRNA was positively correlated with c-Met expression(P<0.01).Conclusion Increased expression of Ets-1 and c-Met mRNA may be correlated with the development,invasion and metastasis of esophageal squamous cell carcinoma.",
        "keywords": [
            "esophageal squamous cell carcinoma",
            "in situ hybridization",
            "c-Met",
            "atypical hyperplasia",
            "Ets-1"
        ],
        "authors": [
            {
                "name": "WANG Yong-xia",
                "org": "Department of Pathology,Xinxiang Medical College,Xinxiang ,Henan Province,China"
            },
            {
                "name": "DONG Xin",
                "org": "Department of Pathology,Xinxiang Medical College,Xinxiang ,Henan Province,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Pathology,Xinxiang Medical College,Xinxiang ,Henan Province,China"
            },
            {
                "name": "LI Yong-zhen",
                "org": "Department of Pathology,Xinxiang Medical College,Xinxiang ,Henan Province,China"
            },
            {
                "name": "JIAO Yun-juan",
                "org": "Department of Pathology,Xinxiang Medical College,Xinxiang ,Henan Province,China"
            },
            {
                "name": "ZHAO Wei-xing",
                "org": "Department of Pathology,Xinxiang Medical College,Xinxiang ,Henan Province,China"
            }
        ],
        "venue": "Journal of Xinxiang Medical College",
        "year": 2011
    },
    "oonPzLgI": {
        "id": "oonPzLgI",
        "title": "Expressions of KISS-1 and matrix metalloproteinases-9 protein in gastric carcinoma",
        "abstract": "Objective To explore relationship between metastasis suppressor gene KISS-1,matrix metalloproteinase-9(MMP-9) and the invasion,metastasis of gastric carcinoma,in order to provide a theoretical foundation for investigation of metastatic mechanisms and clinical treatment of gastric carcinoma.Methods The expressions of KISS-1 and MMP-9 protein in 36 cases of gastric carcinoma and 36 cases of normal gastric epithelia were detected by immunohistochemistry,and the relationships between them and clinical pathologic parameters were analyzed.The expressions of KISS-1 and MMP-9 protein in BGC-823 cell lines with high invasive ability and MKN-28 cell lines with low invasive ability were detected by Western blot.Results The positive expression rate of KISS-1 protein in gastric carcinoma was significantly lower than that in normal gastric epithelia(P<0.05),and the low expression of KISS-1 protein in gastric carcinoma was correlated with lymph node metastasis(P<0.05).The positive expression rate of MMP-9 protein in gastric carcinoma was significantly higher than that in normal gastric epithelia(P<0.05),and the high expression of MMP-9 protein in gastric carcinoma was correlated with the depth of invasion and the metastasis of lymph node(P<0.05).The expression of KISS-1 has negative correlation with the expression of MMP-9(P<0.05).The protein level of KISS-1 was slightly lower in BGC-823 cells than in MKN-28 cells,but the difference was not statistically significant(P>0.05).The protein level of MMP-9 was significantly higher in BGC-823 cells than that in MKN-28 cells(P<0.05).Conclusion Low expression of KISS-1 and high expression of MMP-9 protein may be related with invasion and metastasis of gastric carcinoma.KISS-1 and MMP-9 could be the markers to evaluate invasion and metastasis in gastric carcinoma.",
        "keywords": [
            "gastric carcinoma",
            "immunohistochemistry",
            "matrix metalloproteinase-9",
            "KISS-1",
            "Western blot"
        ],
        "authors": [
            {
                "name": "WANG Hong-xing",
                "org": "Department of Clinical Immunology,Xinxiang Medical College,Xinxiang ,Henan Province,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Pathology,Xinxiang Medical College,Xinxiang ,Henan Province,China"
            },
            {
                "name": "ZHU Hui-fang",
                "org": "Department of Pathology,Xinxiang Medical College,Xinxiang ,Henan Province,China"
            },
            {
                "name": "LI Na",
                "org": "Department of Pathology,Xinxiang Medical College,Xinxiang ,Henan Province,China"
            }
        ],
        "venue": "Journal of Xinxiang Medical College",
        "year": 2012
    },
    "qGjcKRaQ": {
        "id": "qGjcKRaQ",
        "title": "Establishment and characteristics of multidrug-resistant Lewis lung cancer cell line]",
        "abstract": "To establish an ADM resistant Lewis lung cancer cell line and to investigate its biological characteristics.The multidrug-resistant cell line was gradually induced by ADM from Lewis lung cancer cell line (L3-8), its growth characteristics and cancinogenicity were observed. The fluorescent density of ADM and Rh-B in the cells were analyzed by IPP image analysis system. The ADM concentration in cells was assayed with fluorescent meter. The IC50 was evaluated by MTT assay and the drug resistant index was counted.The drug resistant Lewis lung cancer cell line, L3-8/ADM, which can grow in the medium containing 0.4mg/l ADM was acquired after 14 months selective culture. Its tumor generatic rate was 10/10. When the L3-8/ADM was cultured in 0.15mg/l ADM and general 1640 medium, the doubling time was 22.0h and 21.8h separately. After culturing in 4mg/l ADM and Rh-B medium, the fluorescent density ratio of L3-8/ADM and L3-8 were 2.82:1 and 2.65:1 separately. The ADM concentration of L3-8/ADM was only 64.7% of its parental, but there was no significant difference in their ADM release rate. Except for ADM, L3-8/ADM was resistant to DNR, VCR, MIT and CDDP in different degrees.L3-8/ADM cell is a typical MDR cell line. The cell membrane obstruction of drug infiltration might be the cause of drug resistance. This study will provide a basis for the establishment of lung cancer MDR animal model.",
        "keywords": [
            "inducement",
            "lewis lung carcinoma",
            "multidrug-resistance"
        ],
        "authors": [
            {
                "name": "Yanrong Lu",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Ping Lin",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Xiujie Wang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Xiaozhong Huang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Qizhi Ning",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            }
        ],
        "venue": "Zhongguo fei ai za zhi = Chinese journal of lung cancer",
        "year": 2002
    },
    "jYtbVErc": {
        "id": "jYtbVErc",
        "title": "Anticancer activity of litchi fruit pericarp extract against human breast cancer in vitro and in vivo.",
        "abstract": "Litchi fruit pericarp (LFP) extract contains significant amounts of polyphenolic compounds and exhibits powerful antioxidative activity against fat oxidation in vitro. The purpose of this study is to confirm the anticancer activity of LFP extract on human breast cancer in vitro and in vivo, and to elucidate the mechanism of its activity. Human breast cancer cells were tested in vitro for cytotoxicity, colony formation inhibition, BrdU incorporation, and gene expression profiling after treatment with LFP extract. Seven nude mice bearing human breast infiltrating duct carcinoma orthotopically were tested for its anticancer activity and expression of caspase-3 in vivo by oral administration of 0.3% (0.3 mg/ml) of LFP water-soluble crude ethanolic extract (CEE) for 10 weeks. LFP extract demonstrated a dose- and time-dependent inhibitory effect on cell growth (IC(50) = 80 microg/ml), and it significantly inhibited colony formation and BrdU incorporation of human breast cancer cells. Oligonucleotide microarray analysis identified 41(1.22%) up-regulated and 129 (3.84%) down-regulated genes after LFP water-soluble CEE treatment; the predominantly up-regulated genes were involved in various biological functions including cell cycle regulation and cell proliferation, apoptosis, signal transduction and transcriptional regulation, and extracellular matrix/adhesion molecules; and down-regulated genes were mainly associated with adhesion, invasion, and malignancy of cancer cells. A 40.70% tumor mass volume reduction and significant increase of casepase-3 protein expression were observed in vivo experiment. The findings in this study suggested that LFP extract might have potential anticancer activity on both ER positive and negative breast cancers, which could be attributed, in part, to its DNA damage effect, proliferating inhibition and apoptosis induction of cancer cells through up-regulation and down-regulation of multiple genes involved in cell cycle regulation and cell proliferation, apoptosis, signal transduction and transcriptional regulation, motility and invasiveness of cancer cells; ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)-like 1 (ADPRTL1), Cytochrome P450, subfamily I (CYP1A1) and Hyaluronan-mediated motility receptor (HMMR) might be the main molecular targets at which LFP water-soluble CEE acted.",
        "keywords": [
            "apoptosis",
            "growth inhibition",
            "litchi fruit pericarp extract",
            "breast cancer",
            "anticancer activity",
            "cell proliferation",
            "transcription regulation",
            "cell growth",
            "extracellular matrix",
            "signal transduction",
            "poly adp ribose polymerase",
            "cell cycle regulation",
            "water soluble",
            "protein expression",
            "dna damage"
        ],
        "authors": [
            {
                "name": "Xiujie Wang",
                "org": ""
            },
            {
                "name": "Shulan Yuan",
                "org": "Division of Experimental Oncology, National Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, P.R. China"
            },
            {
                "name": "Jing Wang",
                "org": "Division of Experimental Oncology, National Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, P.R. China"
            },
            {
                "name": "Ping Lin",
                "org": "Division of Experimental Oncology, National Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, P.R. China"
            },
            {
                "name": "Guanjian Liu",
                "org": "Department of Clinical Epidemiology, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, P.R. China"
            },
            {
                "name": "Yanrong Lu",
                "org": "Division of Experimental Oncology, National Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, P.R. China"
            },
            {
                "name": "Jie Zhang",
                "org": "Division of Experimental Oncology, National Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, P.R. China"
            },
            {
                "name": "Wendong Wang",
                "org": "Department of Pathology of Public Health School, Sichuan University, Chengdu 610041, Sichuan Province, P.R. China"
            },
            {
                "name": "Yuquan Wei",
                "org": ""
            }
        ],
        "venue": "Toxicology and applied pharmacology",
        "year": 2006
    },
    "rMXFqsT7": {
        "id": "rMXFqsT7",
        "title": "Growth inhibition and multidrug resistance-reversing effect of tanshinone I A on human breast cancer cell with estrogen receptor negative]",
        "abstract": "To investigate the growth inhibition and multidrug resistance (MDR) reversing effect of tanshinone I A on human breast cancer cells with estrogen receptor (ER) negative, and to elucidate its mechanism of activity.Human ER negative breast cancer cells (MDA-MB-231) were tested in vitro for cytotoxicity and colony formation inhibition. Brdu incorporation and cell cycle distribution were also checked through flow cytometry (FCM). With RT-PCR, the expressions of ADP-ribosyltransferase CNAD+; poly (ADP-ribose) polymerase)-like 1 (ADPRTL1), cytochrome P450 subfamily I (CYP1A1) and breast cancer resistance protein (BCRP/ABCG2) mRNA were detected for testing the response to tanshinone 1 A treatment.After tanshinone I A treatment, the proliferation, colony formation and Brdu labeling indices of cancer cells decreased (P<0. 05). By FCM analysis, the increase of subG, and G0/G1 phase cell populations and decrease of S and G2/M phase cells were observed (P<O. 01), both ADPRTL1 and CYP1A1 mRNA expression increased (P< 0. 05), while BCRP/ABCG2 mRNA expression was decreasing (P<0. 05).The findings in these studies suggest that tanshinone I A exhibits the potent cytotoxicity and MDR reversing potential to human ER negative breast cancer cells. The mechanism for such effects may be associated with the inhibition of DNA synthesis, induction of apoptosis, cell cycle arrest and up-regulation of ADPRTL1, CYP1A1, and down-regulation of BCRP/ABCG2 expression in cancer cells.",
        "keywords": [
            "breast cancer resistant protein",
            "growth inhibition",
            "tanshinone ii a",
            "breast cancer",
            "estrogen receptor"
        ],
        "authors": [
            {
                "name": "Jing Jing",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Hong Zheng",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Jing Wang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Ping Lin",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Zhu-juan Xiong",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Ya-ying Wu",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Jing-jing Ren",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Hong-liang Yang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Xiu-jie Wang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            }
        ],
        "venue": "Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition",
        "year": 2007
    },
    "fSp8jMl1": {
        "id": "fSp8jMl1",
        "title": "Inhibitory effect of liver solubility compound of different dosages and different approaches on the proliferation of cancer cells: An in vitro and in vivo study",
        "abstract": "AIM: Liver solubility compound can protect liver and stimulate hepatic tissue regeneration. This study was designed to investigate the inhibitory effect of liver solubility compound on the proliferation of cancer cells. METHODS: The experiment was performed at the Division of Experimental Oncology, National Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University from May 2006 to February 2007. ①Hepatic tissues were prepared separately from the human embryo liver, adult mouse liver and the neonatal mouse liver, washed with saline, sheared, filtered with grit and prepared into suspension with saline, centrifugated at 3 000 r/min. Supernatant was collected to prepare liver solubility compound. ②The different liver solubility complexes dealt with tumor cells separately in vitro. MTT assay was employed to test the effect of liver solubility compound on the proliferation of EMT6 tumor cells in vitro. ③The mice loading EMT6 were treated by liver solubility compound in vivo, and then the growth of cancer and survival condition was observed, including different dosages and different administration approaches. Administration approaches included opposite side oxter and homonymy oxter where inoculated tumor cells, intraperitoneal injection, intragastric administration and so on. RESULTS: ①In vitro study showed that the different source liver solubility compound inhibited the proliferation of EMT6 cells, and the inhibitory rate was significantly higher than the serum albumin group (P < 0.05) and presented dosage dependence. ②The inhibitory rate of liver solubility compound from adult mice in the 8 mg/L group was higher than that in the 2, 4 mg/L group (P < 0.05), and no significant toxic and side effects were found. ③The inhibitory rate of homonymy injection group was higher than that in the other groups (P < 0.05), and the growth rate of body mass was higher in the adult mice liver solubility compound administration group than the corresponding saline control group (P < 0.05). ④The survival phase was significantly prolonged in the adult mice liver solubility compound by homonymy oxter than the mice of the saline control group (P < 0.05). CONCLUSION: The mouse liver solubility compound has cytotoxicity on mice cancer cells and presents dose dependent. Of the different administration approaches, incubation at homonymy oxter can have the best inhibitory effect.",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Hongliang Yang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Zhanpei Liu",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Ping Lin",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Xiujie Wang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Jiang Ren",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "ZhuJuan Xiong",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Qizhi Ning",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            }
        ],
        "venue": "Journal of Clinical Rehabilitative Tissue Engineering Research",
        "year": 2007
    },
    "EBtDWgmL": {
        "id": "EBtDWgmL",
        "title": "Growth inhibition and induction of apoptosis and differentiation of tanshinone IIA in human glioma cells.",
        "abstract": "Tanshinone IIA is a derivative of phenanthrene-quinone isolated from Danshen, a widely used Chinese herbal medicine. It has antioxidant properties, cytotoxic activities against multiple human cancer cells, inducing apoptosis and differentiation of some human cancer cells. The purpose of this study is to confirm its anticancer activity on human glioma cells, and to elucidate mechanism of its activity. Human glioma cells were tested in vitro for cytotoxicity, colony formation inhibition, BrdU incorporation after treatment with tanshinone IIA. Its effect of apoptosis induction was detected through EB/AO staining, cell cycle analysis and the expressions of ADPRTL1 and CYP1A1 genes, the differentiation induction effect was investigated through morphology, mRNA and protein expressions of GFAP and nestin genes by RT-PCR and immunocytochemistry. Tanshinone IIA demonstrated a dose- and time-dependent inhibitory effect on cell growth, IC(50) was 100 ng/ml, and it significantly inhibited colony formation and BrdU incorporation of human glioma cells. After treatment with 25-100 ng/ml of tanshinone IIA, the apoptotic cells increased significantly (P < 0.01), the cells in G(0)/G(1) phase increased (P < 0.01), and decreased in S phase, ADPRTL1 and CYP1A1 mRNA expression increased 1-2 folds. The cells treated with 100 ng/ml tanshinone IIA demonstrated astrocytes or neuron-like morphology, GFAP mRNA and protein expressions increased, nestin mRNA and protein expressions decreased significantly. The findings in this study suggested that tanshinone IIA exhibited strong effects on growth inhibition and induction of apoptosis and differentiation in human glioma cells. It might serve as a novel promising differentiation-inducing and/or therapeutic agent for human gliomas, and need to be investigated further.",
        "keywords": [
            "tanshinone iia æ anticancer activity æ glioma æ growth inhibition æ apoptosis æ differentiation induction",
            "cell growth",
            "cell cycle",
            "protein expression"
        ],
        "authors": [
            {
                "name": "Jing Wang",
                "org": "Division of Experimental Oncology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, 610041 Sichuan P.R. China"
            },
            {
                "name": "Xiujie Wang",
                "org": "Division of Experimental Oncology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, 610041 Sichuan P.R. China"
            },
            {
                "name": "Shu Jiang",
                "org": "Department of Neourosurgery, West China Hospital, Sichuan University, Chengdu, 610041 Sichuan P.R. China"
            },
            {
                "name": "Shulan Yuan",
                "org": "Division of Experimental Oncology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, 610041 Sichuan P.R. China"
            },
            {
                "name": "Ping Lin",
                "org": "Division of Experimental Oncology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, 610041 Sichuan P.R. China"
            },
            {
                "name": "Jie Zhang",
                "org": "Division of Experimental Oncology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, 610041 Sichuan P.R. China"
            },
            {
                "name": "Yanrong Lu",
                "org": "Division of Experimental Oncology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, 610041 Sichuan P.R. China"
            },
            {
                "name": "Qi Wang",
                "org": "Division of Experimental Oncology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, 610041 Sichuan P.R. China"
            },
            {
                "name": "Zhujuan Xiong",
                "org": "Division of Experimental Oncology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, 610041 Sichuan P.R. China"
            },
            {
                "name": "Yaying Wu",
                "org": "Division of Experimental Oncology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, 610041 Sichuan P.R. China"
            },
            {
                "name": "Jingjing Ren",
                "org": "Division of Experimental Oncology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, 610041 Sichuan P.R. China"
            },
            {
                "name": "Hongliang Yang",
                "org": "Division of Experimental Oncology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, 610041 Sichuan P.R. China"
            }
        ],
        "venue": "Journal of neuro-oncology",
        "year": 2007
    },
    "4RnFJ92H": {
        "id": "4RnFJ92H",
        "title": "Establishment of a new human glioblastoma multiforme cell line (WJ1) and its partial characterization.",
        "abstract": "(1) A new human glioblastoma multiforme (GBM) cell line, WJ1, was established from the tissue derived from a 29-year-old patient diagnosed with a grade IV GBM. (2) The WJ1 cell line has been subcultured for more than 80 passages in standard culture media without feeder layer or collagen coatings. (3) GBM cells grow in vitro with distinct morphological appearance. Ultrastructural examination revealed large irregular nuclei and pseudo-inclusion bodies in nuclei. The cytoplasm contained numerous immature organelles and a few glia filaments. Growth kinetic studies demonstrated an approximate population doubling time of 60 h and a colony forming efficiency of 4.04%. The karyotype of the cells was hyperdiploid, with a large subpopulation of polyploid cells. Drug sensitivities of DDP, VP-16, tanshinone IIA of this cell line were assayed. They showed a dose- and time-dependent growth inhibition effect on the cells. (4) Orthotopic transplantation of GBM cells into athymic nude mice induced the formation of solid tumor masses about 6 weeks. The cells obtained from mouse tumor masses when cultivated in vitro had the same morphology and ultrastructure as those of the initial cultures. (5) This cell line may provide a useful model in vitro and in vivo in the cellular and molecular studies as well as in testing novel therapies for human glioblastoma multiforme.",
        "keywords": [
            "brain neoplasm",
            "glioblastoma multiforme",
            "human glioma cell lines",
            "inclusion bodies",
            "doubling time",
            "cell line"
        ],
        "authors": [
            {
                "name": "Jing Wang",
                "org": "Laboratory of Experimental Oncology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China"
            },
            {
                "name": "Xiujie Wang",
                "org": "Laboratory of Experimental Oncology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China"
            },
            {
                "name": "Shu Jiang",
                "org": "Neourosurgery Department, West China Hospital, Sichuan University, Chengdu, Sichuan Province 610041, P. R. China"
            },
            {
                "name": "Ping Lin",
                "org": "Laboratory of Experimental Oncology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China"
            },
            {
                "name": "Jie Zhang",
                "org": "Laboratory of Experimental Oncology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China"
            },
            {
                "name": "Yaying Wu",
                "org": "Laboratory of Experimental Oncology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China"
            },
            {
                "name": "Zhujuan Xiong",
                "org": "Laboratory of Experimental Oncology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China"
            },
            {
                "name": "Jing Jing Ren",
                "org": "Laboratory of Experimental Oncology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China"
            },
            {
                "name": "Hongliang Yang",
                "org": "Laboratory of Experimental Oncology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China"
            }
        ],
        "venue": "Cellular and molecular neurobiology",
        "year": 2007
    },
    "Zz63HO7v": {
        "id": "Zz63HO7v",
        "title": "Interaction between member LIGHT of TNF superfamily and SOCS3, which respond to induce the differentiation and maturation of dendritic cell",
        "abstract": "Objective To detect the relation between the member LIGHT of TNF superfamily and the suppressor of cytokine signaling 3 (SOCS3), and to investigate the effect of SOCS3 on dendritic cell (DC) maturation induced by LIGHT. Methods Bone marrow-derived DC (BMDC) was generated from mouse bone marrow monocyte by culturing with rmGM-CSF, rmIL-4 in vitro. SOCS3 mRNA in BMDC was analyzed by RT-PCR, and the protein of SOCS3 was measured by Western blot. After blocking the SOCS3 expression with the specific anti-sense oligonucleotide, we applied the flow cytometry to measure the expression of CD86 and CD40 on DC for making clear whether the silence of SOCS3 would regulate the LIGHT-stimulated DC maturation. Results With the effect of LIGHT, the level of SOCS3 mRNA and protein in BMDC sharply increased. The specific anti-sense oligonucleotide could effectively block SOCS3 mRNA expressing in BMDC with the ratio of 49% and block SOCS3 protein expression with the ratio of 45%. Compared with SOCS3-unblocked DC, the SOCS3-blocked BMDC with stimulation of LIGHT showed higher CD40 and CD86 (P<0. 05). Conclusion LIGHT enhances the expression of SOCS3 during stimulating BMDC maturation. As more sensitive to LIGHT, the SOCS3-blocked BMDC is driven to more mature. SOCS3 presents a negative regulation mechanism in BMDC maturation induced by LIGHT.",
        "keywords": [
            "Dendritic cells",
            "Differentiation and maturation",
            "LIGHT",
            "SOCS3"
        ],
        "authors": [
            {
                "name": "Ping Lin",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Qi Wang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Yan-rong Lu",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Xiu-jie Wang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Zhu-juan Xiong",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Hong-liang Yang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Jing-jing Ren",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            }
        ],
        "venue": "Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition",
        "year": 2007
    },
    "7VIQSj2s": {
        "id": "7VIQSj2s",
        "title": "Partial biological characterization of cancer stem-like cell line (WJ(2)) of human glioblastoma multiforme.",
        "abstract": "To provide suitable models for human GBM cancer stem cells in vitro and in vivo, and investigate their biological characteristics,\n a new human GBM cancer stem-like cell line, WJ2, was established in this experiment through serial passages from adherent\n monolayer culture to nonadherent tumor sphere culture in turns; Its partial biological characteristics were studied through\n cell proliferation and tumor sphere assay; cell cycle distribution, side population, and CD133 phenotype were analyzed with\n FCM. The expressions of CD133, Nestin, and GFAP of cancer stem-like cells and xenograft tumor cells were detected with RT-PCR\n and immunohistochemistry. Biological characterization, side population, CD133 phenotype and CD133 Nestin, BCRP-1, Wnt-1 gene\n expression revealed the stemness of this cancer stem-like cell line. Tumorigenicity heterotransplanted in nude mice; histopathological\n characteristics of xenograft tumor, and expressions of CD133, Nestin, and GFAP of xenograft tumor cells indicated that xenograft\n tumors recapitulated the phenotype and biological characterization of human primary GBM. All findings of this experimental\n study suggested that WJ2 cancer stem-like cell line could accurately mimic human GBM cancer stem cell in vitro and in vivo; it would be useful in\n the cellular and molecular studies as well as in testing novel therapies of CSC-based anti-cancer therapies for human GBM.",
        "keywords": [
            "brain neoplasm",
            "cancer stem cell line",
            "glioblastoma multiforme",
            "cancer stem cell",
            "cell line",
            "cell cycle",
            "cell proliferation",
            "immunohistochemistry",
            "gene expression"
        ],
        "authors": [
            {
                "name": "Jing Wang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Xiujie Wang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Shu Jiang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Ping Lin",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Yaying Wu",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Zhujuan Xiong",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Jing Jing Ren",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Hongliang Yang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            }
        ],
        "venue": "Cellular and molecular neurobiology",
        "year": 2008
    },
    "RqNGvcLZ": {
        "id": "RqNGvcLZ",
        "title": "Cytotoxicity of fig fruit latex against human cancer cells.",
        "abstract": "Fig fruit latex (FFL) contains significant amounts of polyphenolic compounds and can serve as a source of antioxidants after human consumption. The purpose of this study is to confirm anticancer activity of FFL against human cancer cells and to further elucidate its mechanism of activity. Human glioblastoma, hepatocellular carcinoma, and normal liver cells were used for in vitro tests of FFL effects. Those tests included cytotoxicity, colony formation inhibition, Brdu incorporation, acridine orange/ethidium bromide (AO/EB) staining for apoptotic cells, cell cycle distribution through flow cytometry (FCM), and ADP-ribosyltransferase (NAD+; poly(ADP-ribose) polymerase)-like 1 (ADPERL1) mRNA expression through RT-PCR in response to FFL treatment. After FFL treatment, the proliferation, colony formation, and Brdu labeling indices of cancer cells decreased (P<0.05), while the AO/EB stained apoptotic cells increased (P<0.05). By FCM analysis, an increase of G(0)/G(1) phase cell population and decrease of S and G(2)/M phase cells were observed (P<0.01), while both ADPRTL1 mRNA expression and apoptotic indices increased (P<0.01). The findings in these studies suggested that FFL exhibited potent cytotoxicity in some human cancer cells with little effect in normal cells at certain concentration. The mechanism for such effects might be associated with the inhibition of DNA synthesis, induction of apoptosis, and cell cycle arrest of cancer cells.",
        "keywords": [
            "apoptosis",
            "fig fruit latex",
            "growth inhibition",
            "human cancer cells",
            "dna synthesis",
            "cell cycle arrest",
            "flow cytometry",
            "poly adp ribose polymerase",
            "cell growth",
            "cell cycle"
        ],
        "authors": [
            {
                "name": "Jing Wang",
                "org": "Division of Experimental Oncology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, PR China"
            },
            {
                "name": "Xiujie Wang",
                "org": ""
            },
            {
                "name": "Shu Jiang",
                "org": "Neourosurgery Department, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, PR China"
            },
            {
                "name": "Ping Lin",
                "org": "Division of Experimental Oncology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, PR China"
            },
            {
                "name": "Jie Zhang",
                "org": "Division of Experimental Oncology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, PR China"
            },
            {
                "name": "Yanrong Lu",
                "org": "Division of Experimental Oncology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, PR China"
            },
            {
                "name": "Qi Wang",
                "org": "Division of Experimental Oncology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, PR China"
            },
            {
                "name": "Zhujuan Xiong",
                "org": "Division of Experimental Oncology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, PR China"
            },
            {
                "name": "Yaying Wu",
                "org": "Division of Experimental Oncology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, PR China"
            },
            {
                "name": "Jingjing Ren",
                "org": "Division of Experimental Oncology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, PR China"
            },
            {
                "name": "Hongliang Yang",
                "org": "Division of Experimental Oncology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, PR China"
            }
        ],
        "venue": "Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association",
        "year": 2008
    },
    "ESD4k1Sa": {
        "id": "ESD4k1Sa",
        "title": "Construction of eukaryotic expression plasmid pEGFP- ATPB1 and its effect on gastric adenocarcinoma cell SGC-7901",
        "abstract": "Objective To establish the eukaryotic expression plasmid containing the code gene of Na+, K+-ATPase β1-subunit (ATP1B1) and the basis of ATP1B1 applied to antitumor gene therapy. Methods The ATP1B1 cDNA was amplified from leukocyte gene library and then cloned into the eukaryotic expression vector pEGFP-C3. The recombinant plasmid, named as pEGFP-ATP1B1, was determined with restriction enzyme and sequencing analyses. Next pEGFP-ATP1B1 was transferred into gastric adenocarcinoma SGC-7901 cells by lipofectamine, then ATP1B1 mRNA expression in transfected cells was detected by real-time PCR, and also ATPase was detected after cell transfection, as well as the proliferation of such cells was measured by MTT. Results The analysis confirmed that the recombinant pEGFP-ATP1B1 contained the ATP1B1 cDNA. After cell transfection, the expression of ATP1B1 mRNA(129. 2%) and the activity of ATPase [(2. 95±0. 210)%] were higher, and the growth of the SGC-7901 cells transfected with ATP1B1 was inhibited obviously when compared with the control group. Conclusion The recombinant pEGFP-ATP1B1 is constructed successfully, and this recombinant eukaryotic expression vector could be used in additional studies on the biological effect of ATP1B1 and its use in anti-tumor gene therapy.",
        "keywords": [
            "Cancer gene therapy",
            "Gastric adenocarcinoma SGC-7901 cells",
            "K+-ATPase β1-subunit",
            "Na+",
            "Transfection"
        ],
        "authors": [
            {
                "name": "Zhu-Juan Xiong",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Ping Lin",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Xiu-Jie Wang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Qi Wang.",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Jing-Jing Ren",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Hong-Liang Yang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Jing Wang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Ya-Ying Wu",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            }
        ],
        "venue": "Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition",
        "year": 2008
    },
    "4Dlp3mQ4": {
        "id": "4Dlp3mQ4",
        "title": "Primary study on preparation and efficiency of neotype hepatocellular carcinoma-dendritic cell vaccine with SOCS1 expression inhibited",
        "abstract": "Objective To investigate the effect of SOCS1 expression inhibition on hepatocellular carcinoma-dendritic cell vaccine stimulated by LIGHT. Methods The dendritic cells (DC) were generated from mouse bone marrow (BMDC) by cultured in medium containing rmGM-CSF and rmIL-4. The vaccine cells were prepared by loaded with hepatocellular carcinoma HepA antigen and further treated with or without LIGHT and SOCS1 antisense oligonucleotide (AS1). For detecting the maturity of the vaccine cells, the expression of the cell's surface molecules CD40 and CD86 were measured by FACS, and IL-12 and IL-1 secretion from the cells were determined by ELISA. And the CTL activity, cellular proliferation, IL-6 and TNF-β secretion levels of the vaccine-stimulated lymphocytes were also assessed for analyzing the immune response of lymphocyte. Results CD40 and CD86 expression of the prepared vaccine cells were obviously enhanced by treatment of LIGHT and AS1, and so were IL-12 and IL-1 (P<0.01). It was also observed that CTL activity, cellular proliferation and IL-6 and TNF-β secreting levels of lymphocytes that were stimulated by the vaccine cells treated with AS1 were notably enhanced. Conclusion Inhibiting SOCS1 can improve the maturation of hepatocellular carcinoma-DC vaccine cell and can increase its inducing ability of anti-cancer immune response.",
        "keywords": [
            "Dendritic cell vaccine",
            "Hepatocellular carcinoma",
            "Socs1 inhibition"
        ],
        "authors": [
            {
                "name": "Zhan-Pei Liu",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Ping Lin",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Xiu-Jie Wang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Qi Wang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            }
        ],
        "venue": "Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition",
        "year": 2008
    },
    "Jh7VrBh0": {
        "id": "Jh7VrBh0",
        "title": "Synergic effect of Na+-K+ ATPaseB1 and adriamycin on inhibition of cell proliferation and reversal of drug resistance in breast cancer MCF-7 cells",
        "abstract": "Background and Objective: Na+-K+ATPase (Na+-K+ pump) is an important cell energy conversion system which is probably associated with tumor metastasis. Expression of its B1 subunit gene-ATP1B1 is high in well differentiated and low in poorly differentiated tumor cells. This study was to investigate the synergic effect of Na+-K+ ATPaseB1 and adriamycin (ADM) on inhibition of cell proliferation and reversal of drug resistance in MCF-7 and MCF-7 / ADM cells. Methods: Growth of MCF-7 and MCF-7 / ADM cells transfected with PEGFP-ATP1B1 and shATP1B1 were measured by MTT. Intracellular fluorescence intensity of ADM was analyzed by inverted fluorescence microscopy and flow cytometry. ATP enzyme activity was measured by ultramicro-ATP enzyme, and mRNA expression of multi-drug resistance gene MDR1 was detected by RT-PCR and real-time PCR. The expression of P-glycoprotein (P-gp) was analyzed by western blot. Results: The sensitivity of MCF-7 and MCF-7 / ADM cells transfected with pEGFP- ATP1B1 to ADM was higher in comparing to the negative control ADM-C3 (transfected with vector pEGFP-C3) and the control ADM-RPMI-1640 (cultured with RPMI-1640), and the differences between ADM-ATP1B1 and ADM-RPMI-1640 groups were statistically significant at different concentrations of adriamycin (P<0.05). After the B1 subunit was silenced, the sensitivity of cells to ADM in the ADM-shNC group was higher than that in the shATP and ADM-RPMI-1640 groups. The mean fluorescence intensity of ADM in the ADM-ATP1B1 group was higher than that in the ADM-C3 and ADM-RPMI-1640 groups (P<0.05). ATP enzyme activity was significantly higher in ADM-ATP1B1 group comparing to the ADM-RPMI-1640 group (P<0.05). mRNA expression of MDR1 gene and protein expression of P-gp were not significantly different among the ADM-ATP1B1 group and two control groups (P >0.05). Conclusion: Na +-K + ATPase B1 can synergize with ADM and reverse drug resistance to ADM in the MCF-7/ADM cell line. This may be related to ATP enzyme activity, but not to influencing the expression of MDR1 gene.",
        "keywords": [
            "mcf-7",
            "breast cancer",
            "adriamycin",
            "na+-k+ atpase b1 subunit",
            "reversal of drug resistance"
        ],
        "authors": [
            {
                "name": "Yan-Yu Qi",
                "org": "Division of Geraeology, State Key Laboratory of Biotherapy, West China Hospital, Chengdu, Sichuan University, , P.R. China"
            },
            {
                "name": "Kai Liu",
                "org": "Division of Geraeology, State Key Laboratory of Biotherapy, West China Hospital, Chengdu, Sichuan University, , P.R. China"
            },
            {
                "name": "Jie Zhang",
                "org": "Division of Geraeology, State Key Laboratory of Biotherapy, West China Hospital, Chengdu, Sichuan University, , P.R. China"
            },
            {
                "name": "Kai Li",
                "org": "Division of Geraeology, State Key Laboratory of Biotherapy, West China Hospital, Chengdu, Sichuan University, , P.R. China"
            },
            {
                "name": "Jing-Jing Ren",
                "org": "Division of Geraeology, State Key Laboratory of Biotherapy, West China Hospital, Chengdu, Sichuan University, , P.R. China"
            },
            {
                "name": "Ping Lin",
                "org": "Division of Geraeology, State Key Laboratory of Biotherapy, West China Hospital, Chengdu, Sichuan University, , P.R. China"
            }
        ],
        "venue": "Ai zheng = Aizheng = Chinese journal of cancer",
        "year": 2009
    },
    "jWilzAez": {
        "id": "jWilzAez",
        "title": "Construction of eukaryotic expression plasmid for a novel zinc finger protein gene Zf p637 and its effect on breast carcinoma cell EMT6",
        "abstract": "Objective To construct the eukaryotic expression plasmid and establish stably transfected cell line, which contained the code gene of zinc finger protein637(Zfp637), and to observe the effect of Zfp637 gene to the proliferation of tumor cells. Methods The Zfp637 DNA was amplified from the template of normal spleen tissue cDNA and cloned into the eukaryotic expression vector pEGFP-C3. The recombinant plasmid, named as pEGFP-Zfp637, was determined by restriction enzyme and sequencing analyses. Next the pEGFP-Zfp637 recombinant plasmid was transferred into mouse breast carcinoma EMT6 cells with lipofectamine 2000, and the stably transfected cells were selected by G418(named Zfp637-EMT6). The growth condition of cells was observed, and subcellular localization of Zfp637 gene was located by fluorescence microscope at the same time. The Zfp637 mRNA expression in the transfected cells was detected by RT-PCR, and the proliferation of such cells was measured by MTT. Results The analysis confirmed that the recombinant pEGFP-Zfp637 contained the Zfp637 full-length cDNA. The Zfp637 mRNA was over-expressed stably in Zfp637-EMT6. The growth of Zfp637- EMT6 was increased obviously when compared with the negative control group and blank group. Conclusion The recombinant pEGFP-Zfp637 has been constructed successfully, and the expression of the Zfp637 gene can promote the proliferation of cells. This recombinant eukaryotic expression plasmid can be used in advanced studies in the biological effects of Zfp637 and anti-tumor gene therapy.",
        "keywords": [
            "Breast carcinoma",
            "Cellular proliferation",
            "EMT6 Cell",
            "Stable transfection",
            "Zf p637 gene"
        ],
        "authors": [
            {
                "name": "Kai Li",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Jingjing Ren",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Kai Liu",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Yanyu Qi",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Xiujie Wang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Hengyi Xiao",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Ping Lin",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            }
        ],
        "venue": "Journal of Sichuan University (Medical Science Edition)",
        "year": 2009
    },
    "L6a9FKa9": {
        "id": "L6a9FKa9",
        "title": "Interference of human Na/K-ATPaseB1 subunit on proliferation and migration of gastric adenocarcinoma cell line SGC-7901",
        "abstract": "Background and Objective:The Na+ /K+ ATPaseB1(ATP1B1) subunit gene is highly expressed in well-differentiated tumor cells,while it is hypoexpressed in poorly differentiated tumor cells.The expression of ATP1B1 is closely related to cell tight junction and polarity of epithelial cells.This study was to investigate the effect of specific interference of human Na+/K+ ATP1B1 using shRNA on cell proliferation and migration of gastric adenocarcinoma cell line SGC-7901.Methods:Four shRNA plasmids specifically targeting different fragments of ATP1B1,sh150,sh295,sh562,sh765,were constructed and transiently transfected into SGC-7901 cells.Stable positive clones,shATP1B1-7901 cells,were sorted out by G418.The expression of ATP1B1 mRNA was detected by semi-quantitative RT-PCR and real-time PCR.Cell proliferation was measured by MTT,cell cycle distribution was assessed by flow cytometry,and clone forming was analyzed by the colony formation assay.Cellular migration was observed using the Transwell experiment.Results:At 24 h after transfection,the inhibition ratios of sh150,sh295,sh562,sh765 on ATP1B1 mRNA were(60.87 ±4.38)%,(44.93 ± 2.24)%,(52.17±2.60)% and(52.17±2.60)% respectively in SGC-7901 cells,which were significantly higher than that of shNC control(3.00 ± 0.15)%(P <0.05).Among the four ATP1B1 shRNAs,sh150 exerted the strongest effect(P<0.05) and was used in the following study.Assessed by RT-PCR and real-time PCR,the expression of ATP1B1 mRNA was inhibited by(85.72±5.22)% and(87.53±3.23)% in the shATP1B1-7901 group,in comparison with(3.3±0.22)% and(4.17±0.33)% in the shNC-7901 group(P<0.05).The proliferation ratio was higher in the shATP1B1-7901 group than in the shNC-7901 and SGC-7901 groups 3 days after transfection(P<0.05).Cells at S and G2/M phases in the shATP1B1-7901 group were significantly increased compared with those in the shNC-7901 and SGC-7901 groups(P< 0.05).The clone formation rate of the shATP1B1-7901 group(68.50±2.65)% was higher than that of the shNC-7901 group(50.00 ±2.53)% and of the SGC-7901 group(52.50±2.11)%(P<0.05).Moreover,the migration ratio of the shATP1B1-7901 group(2.80±0.02)% was significantly enhanced comparing to the shNC-7901(1.15±0.05)% and the shNC-7901 groups(1.25±0.02)%(P <0.05).Conclusion:Silencing of ATP1B1 gene can enhance the proliferation and migration capability of SGC-7901 cells.",
        "keywords": [
            "cell proliferation",
            "cell migration",
            "ATPaseB1(ATP1B1)",
            "adenocarcinoma",
            "gastric neoplasm",
            "RNA interference"
        ],
        "authors": [
            {
                "name": "Kai Liu",
                "org": " Department of Geraeology,State Key Laboratory of Biotherapy and Cancer Center,West China Hospital,Sichuan University,Chengdu,Sichuan,,P.R.China"
            },
            {
                "name": "Jie Zhang",
                "org": " Department of Geraeology,State Key Laboratory of Biotherapy and Cancer Center,West China Hospital,Sichuan University,Chengdu,Sichuan,,P.R.China"
            },
            {
                "name": "Jing-Jing Ren",
                "org": " Department of Geraeology,State Key Laboratory of Biotherapy and Cancer Center,West China Hospital,Sichuan University,Chengdu,Sichuan,,P.R.China"
            },
            {
                "name": "Xiu-Jie Wang",
                "org": " Department of Geraeology,State Key Laboratory of Biotherapy and Cancer Center,West China Hospital,Sichuan University,Chengdu,Sichuan,,P.R.China"
            },
            {
                "name": "Hong-Liang Yang",
                "org": " Department of Geraeology,State Key Laboratory of Biotherapy and Cancer Center,West China Hospital,Sichuan University,Chengdu,Sichuan,,P.R.China"
            },
            {
                "name": "Ping Lin",
                "org": " Department of Geraeology,State Key Laboratory of Biotherapy and Cancer Center,West China Hospital,Sichuan University,Chengdu,Sichuan,,P.R.China"
            }
        ],
        "venue": "Chinese Journal of Cancer",
        "year": 2009
    },
    "W5RGJzve": {
        "id": "W5RGJzve",
        "title": "A novel zinc finger protein Zfp637 behaves as a repressive regulator in myogenic cellular differentiation.",
        "abstract": "Zinc finger proteins have been implicated as transcription factors in the differentiation and development of cells and tissues in higher organisms. The classical C2H2 zinc finger motif is one main type of motif of zinc finger proteins. Our previous studies have shown that Zfp637, which comprises six consecutively typical and one atypical C2H2 zinc finger motifs, is highly expressed in undifferentiated or poorly differentiated cell lines, but is moderately or slightly expressed in normal tissues. We have also demonstrated that Zfp637 can promote cell proliferation. However, its role in the regulation of cell differentiation remains unknown. We report here that endogenous Zfp637 as well as mTERT is expressed in proliferating C2C12 myoblasts and that their expression is downregulated during myogenic differentiation. Constitutive expression of Zfp637 in C2C12 myoblasts increased mTERT expression and telomerase activity, and promoted the progression of the cell cycle and cell proliferation. By contrast, endogenous repression of Zfp637 expression by RNA interference downregulated the mTERT gene and the activity of telomerase, and markedly reduced cell proliferation. Overexpression of Zfp637 also inhibited the expression of myogenic differentiation-specific genes such as MyoD and myogenin, and prevented C2C12 myoblast differentiation. Our results suggest that Zfp637 inhibits muscle differentiation through a defect in the cell cycle exit by potentially regulating mTERT expression in C2C12 myoblasts. This may provide a new research line for studying muscle differentiation.",
        "keywords": [
            "zinc finger protein",
            "c2c12 muscle cell",
            "mtert",
            "cell differentiation",
            "cell cycle",
            "cellular differentiation"
        ],
        "authors": [
            {
                "name": "Kai Li",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Jing-Jing Ren",
                "org": ""
            },
            {
                "name": "Qi Wang",
                "org": ""
            },
            {
                "name": "Kai-Yong Yang",
                "org": ""
            },
            {
                "name": "Zhu-Juan Xiong",
                "org": ""
            },
            {
                "name": "Yong-Qiu Mao",
                "org": ""
            },
            {
                "name": "Yan-Yu Qi",
                "org": ""
            },
            {
                "name": "Xiao-Wei Chen",
                "org": ""
            },
            {
                "name": "Feng Lan",
                "org": ""
            },
            {
                "name": "Xiu-Jie Wang",
                "org": ""
            },
            {
                "name": "Heng-Yi Xiao",
                "org": ""
            },
            {
                "name": "Ping Lin",
                "org": ""
            },
            {
                "name": "Yu-Quan Wei",
                "org": ""
            }
        ],
        "venue": "Journal of cellular biochemistry",
        "year": 2010
    },
    "PmCrJF0l": {
        "id": "PmCrJF0l",
        "title": "IL-23/IL-23R: potential mediator of intestinal tumor progression from adenomatous polyps to colorectal carcinoma.",
        "abstract": "Interleukin 23 (IL-23) affects tumor growth by regulating Th cells and plays a vital role in immunosuppression in tumor tissues. However, whether tumor cells are IL-23R positive or whether IL-23 has the potential to influence the growth of cancer cells directly remains unclear. The aim of this study was to clarify the molecular expression patterns of IL-23, IL-23R, and Forkhead box P3 (FOXP3) in normal tissues adjacent to cancer, in intestinal polyps (IP), and in colorectal carcinoma (CRC), and to infer the relationship between the expression patterns of these three molecules and the progress of intestinal tumors from adenomatous polyps to colorectal cancer.The levels of IL-23A, IL-23R, and FOXP3 were evaluated in normal tissues adjacent to cancer (NT, n = 13), IP (n = 26), and CRC (n = 13) using real-time PCR, ELISA, western blotting, immunohistochemistry, and immunocytochemistry.The expression of IL-23 and FOXP3 increased progressively from NT through to CRC. Immunohistochemistry staining showed that IL-23R was highly positive in carcinoma cells of the CRC group, whereas it was partially positive in cells of other groups. In addition, the human CRC cell line SW-480 exhibited weak IL-23R immunocytochemical positivity.We propose that the IL-23/IL-23R pathway is a potential route to facilitate the malignant progression of cancers. The relationship between IL-23 and FOXP3 in the microenvironment of carcinoma led us to deduce that these two molecules may interact with each other. Although the exact mechanism underlying this interaction remains a mystery, we are convinced that these two molecules are relevant in cancer progression and that IL-23 could be a potential target for cancer immunotherapy.",
        "keywords": [
            "il-23.il-23 receptor.forkhead box p3. intestinal polyp.colorectal carcinoma",
            "IL-23",
            "IL-23 receptor",
            "Forkhead box P3",
            "Intestinal polyp",
            "Colorectal carcinoma"
        ],
        "authors": [
            {
                "name": "Feng Lan",
                "org": "Division of Geriatrics, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Sichuan, People’s Republic of China"
            },
            {
                "name": "Le Zhang",
                "org": "Division of Geriatrics, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Sichuan, People’s Republic of China"
            },
            {
                "name": "Junchao Wu",
                "org": "Digestive System Department, West China Hospital, Sichuan University, Sichuan, People’s Republic of China"
            },
            {
                "name": "Jie Zhang",
                "org": "Division of Geriatrics, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Sichuan, People’s Republic of China"
            },
            {
                "name": "Sen Zhang",
                "org": "Division of Geriatrics, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Sichuan, People’s Republic of China"
            },
            {
                "name": "Kai Li",
                "org": "Division of Geriatrics, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Sichuan, People’s Republic of China"
            },
            {
                "name": "Yanyu Qi",
                "org": "Division of Geriatrics, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Sichuan, People’s Republic of China"
            },
            {
                "name": "Ping Lin",
                "org": "Division of Geriatrics, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Sichuan, People’s Republic of China"
            }
        ],
        "venue": "International journal of colorectal disease",
        "year": 2011
    },
    "2nqXk05e": {
        "id": "2nqXk05e",
        "title": "Th17 response is augmented in OVA-induced asthmatic mice exposed to HDM.",
        "abstract": "It is widely accepted that T helper 2 (Th2) cells, Th17 cells and their cytokines orchestrate the feature of asthma. However, most of studies on asthma mechanisms use a single allergen challenge model. Actually, humans are concurrently exposed to various allergens, and the mechanism of asthma with complex allergen exposure is less well defined. To explore whether the mechanism would be altered if asthma patients are re-exposed to another allergen, we exposed the chicken egg albumin (OVA) induced-asthmatic mice to house dust mite (HDM).HE staining was used to analyze pathologic variation in lung tissue of mice in each sub-group: control group, HDM alone group, OVA alone group and OVA+HDM group. Th1, Th2 and Th17 associated gene mRNA expressions were detected by quantitative PCR; associated cytokines were determined by ELISA or immunohistochemistry.The severe of inflammatory cell infiltration, the augmentation of Th17 and Th2 related gene mRNA expressions and the increase of Th17 associated cytokines expression were shown in OVA+HDM group in comparison with OVA alone group. However, Th2 related cytokines were increased with no significant difference in OVA+HDM group compared with OVA alone group.We have found that Th17 response is connected with inflammation in the OVA-induced asthmatic mice exposed to HDM. When OVA-induced asthmatic mice are re-exposed to HDM, the pathomechanism is different from OVA alone exposure. HDM, indoor allergen, may be an important interferential factor for asthma therapy. It will give an important direction in the development of future asthma therapy.",
        "keywords": [
            "house dust mite t helper 17 asthma",
            "gene expression regulation",
            "rna"
        ],
        "authors": [
            {
                "name": "Feng Lan",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Kai Liu",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Yanyu Qi",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Kai Li",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Ping Lin",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            }
        ],
        "venue": "Medical science monitor : international medical journal of experimental and clinical research",
        "year": 2011
    },
    "EiUdTADT": {
        "id": "EiUdTADT",
        "title": "Establishment of a monoclonal antibody against a peptide of the novel zinc finger protein ZNF32 proved to be specific and sensitive for immunological measurements.",
        "abstract": "ZNF32 has been predicted to be a zinc finger protein and is involved in cell differentiation and tumor development, but its precise function is unknown. Specific monoclonal antibodies (mAbs) have been widely used in research and clinical diagnosis and treatments. Therefore, we established an anti-ZNF32 mAb to characterize this protein's function.Peptide⁴⁹⁻⁶³, a specific small peptide of ZNF32, was chosen and the synthetic keyhole limpet hemocyanin (KLH)-peptide⁴⁹⁻⁶³ was used as an antigen to immunize mice. A mAb against peptide⁴⁹⁻⁶³ was generated by hybridoma technology, and hybridoma cells were screened by limiting dilution. The isoform of mAb-pZNF32-8D9 was identified by double agar diffusion. The sensitivity and specificity of the mAb and expressed levels of ZNF32 in various cells and tissues were identified by enzyme-linked immunosorbent assay (ELISA), immunocytochemistry, immunohistochemistry, and Western blotting.A stable anti-pZNF32-8D9 hybridoma secreting the anti-peptide49-63 mAb was established and the clone positive to the peptide⁴⁹⁻⁶³ in supernatant was 92% in ELISA. The mAb-pZNF32-8D9 is an immunoglobulin-1 that can be used for detecting the ZNF32 protein by immunocytochemistry, immunohistochemistry, and Western blotting and is highly sensitive and specific. We also found ZNF32 expressed at high levels in Jurkat and pulmonary squamous carcinoma cells, but it was not expressed in squamous epidermis cells.mAb-pZNF32-8D9 can be used for the identification and expression of ZNF32. It might also provide a new tool for diagnostics or therapy for ZNF32-related diseases.",
        "keywords": [
            "hybridomas",
            "monoclonal antibody",
            "peptide",
            "znf32 protein"
        ],
        "authors": [
            {
                "name": "Yuyan Wei",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Kai Li",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Lugang Huang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Jun Li",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Xiujie Wang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Ping Lin",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Yuquan Wei",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            }
        ],
        "venue": "Medical science monitor : international medical journal of experimental and clinical research",
        "year": 2012
    },
    "4X3cfZ6J": {
        "id": "4X3cfZ6J",
        "title": "Establishment of a monoclonal antibody against a peptide of the novel zinc finger protein ZNF32 proved to be specific and sensitive for immunological measurements.",
        "abstract": "",
        "keywords": [
            "limit of detection",
            "cell line",
            "chromosomes",
            "immunohistochemistry",
            "antibodies",
            "amino acid sequence",
            "blotting"
        ],
        "authors": [
            {
                "name": "jie zhang",
                "org": "sichuan university"
            },
            {
                "name": "kai li",
                "org": "sichuan university"
            },
            {
                "name": "lugang huang",
                "org": "sichuan university"
            },
            {
                "name": "jun li",
                "org": "sichuan university"
            },
            {
                "name": "xiujie wang",
                "org": "sichuan university"
            },
            {
                "name": "ping lin",
                "org": "sichuan university"
            },
            {
                "name": "yuquan wei",
                "org": "sichuan university"
            }
        ],
        "venue": "Medical Science Monitor",
        "year": 2012
    },
    "ShBSeKMN": {
        "id": "ShBSeKMN",
        "title": "Interleukin 23 promotes lung adenocarcinoma a549 cell migration and invasion]",
        "abstract": "Interleukin 23 (IL-23) is a pro-inflammatory cytokine that plays an important role in inflammatory disease and tumor microenvironment. The IL-23 receptor is expressed in colon, lung, and oral carcinomas. We performed this study to investigate whether IL-23 promotes directly carcinoma cell migration and invasion as well as further explore its mechanism.The migration and invasion of human lung adenocarcinoma A549 cells induced by IL-23 were detected by a scratch test and Transwell experiment. MMP-9 expression of the mRNA and protein levels of A549 cells cultured with and without IL-23 was respectively detected by Real-time PCR and ELISA. The effect of IL-23 on A549 cells was further verified using anti-IL-23p19 neutralization antibody (Ab IL-23p19) to eliminate IL-23.IL-23 remarkably promoted A549 cell migration and invasion. MMP-9 expression in A549 cells was upregulated by IL-23 stimulation. In addition, the effect of IL-23 on the migration and invasion of A549, as well as the MMP-9 expression in A549 cells induced by IL-23, was eliminated by Ab IL-23p19.IL-23 promotes the migration and invasion of A549 cells by inducing MMP-9 expression.",
        "keywords": [
            "invasion",
            "lung adenocarcinoma cells a549",
            "il-23",
            "migration",
            "mmp-9",
            "il 23"
        ],
        "authors": [
            {
                "name": "Sen Zhang",
                "org": " Division of Geriatrics,State Key Laboratory of Biotherapy,West China Hospital,Sichuan University,Chengdu ,China"
            },
            {
                "name": "Jun Li",
                "org": " Division of Geriatrics,State Key Laboratory of Biotherapy,West China Hospital,Sichuan University,Chengdu ,China"
            },
            {
                "name": "Jie Zhang",
                "org": " Division of Geriatrics,State Key Laboratory of Biotherapy,West China Hospital,Sichuan University,Chengdu ,China"
            },
            {
                "name": "Le Zhang",
                "org": " Division of Geriatrics,State Key Laboratory of Biotherapy,West China Hospital,Sichuan University,Chengdu ,China"
            },
            {
                "name": "Ping Lin",
                "org": " Division of Geriatrics,State Key Laboratory of Biotherapy,West China Hospital,Sichuan University,Chengdu ,China"
            }
        ],
        "venue": "Zhongguo fei ai za zhi = Chinese journal of lung cancer",
        "year": 2012
    },
    "dtYOhoJ1": {
        "id": "dtYOhoJ1",
        "title": "Interleukin 23 promotes lung adenocarcinoma A549 cell migration and invasion | (Chinese Source)",
        "abstract": "Background and objective Interleukin 23 (IL-23) is a pro-inflammatory cytokine that plays an important role in inflammatory disease and tumor microenvironment. The IL-23 receptor is expressed in colon, lung, and oral carcinomas. We performed this study to investigate whether IL-23 promotes directly carcinoma cell migration and invasion as well as further explore its mechanism. Methods The migration and invasion of human lung adenocarcinoma A549 cells induced by IL-23 were detected by a scratch test and Transwell experiment. MMP-9 expression of the mRNA and protein levels of A549 cells cultured with and without IL-23 was respectively detected by Real-time PCR and ELISA. The effect of IL-23 on A549 cells was further verified using anti-IL-23p19 neutralization antibody (Ab IL-23p19) to eliminate IL-23. Results IL-23 remarkably promoted A549 cell migration and invasion. MMP-9 expression in A549 cells was upregulated by IL-23 stimulation. In addition, the effect of IL-23 on the migration and invasion of A549, as well as the MMP-9 expression in A549 cells induced by IL-23, was eliminated by Ab IL-23p19. Conclusion IL-23 promotes the migration and invasion of A549 cells by inducing MMP-9 expression.",
        "keywords": [
            "IL-23",
            "Invasion",
            "Lung adenocarcinoma cells A549",
            "Migration",
            "MMP-9"
        ],
        "authors": [
            {
                "name": "Sen Zhang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Jun Li",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Le Zhang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Ping Lin",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            }
        ],
        "venue": "Chinese Journal of Lung Cancer",
        "year": 2012
    },
    "99SXGe8X": {
        "id": "99SXGe8X",
        "title": "Anticancer potential of aqueous extract of alocasia macrorrhiza against hepatic cancer in vitro and in vivo.",
        "abstract": "Alocasia macrorrhiza has been used as a folk medicine for cancer treatment in the Southwest of China.The purpose of this study is to confirm the anticancer activity of aqueous extract of alocasia macrorrhiza against hepatic cancer and to elucidate its mechanism of action.Human normal liver cells and hepatocellular carcinoma cells were tested in vitro for cytotoxicity, colony formation inhibition, EdU incorporation, AO/EB staining apoptotic cells, apoptotic DNA fragmentation, and cell cycle distribution in response to alocasia macrorrhiza extract. The mRNA and protein expressions of PPARγ, Cyclin D1, Rb, P21, Bax, Bcl-2 and caspase-3 were detected through RT-PCR and Western blotting; the tumor growth inhibition in vivo was tested by oral administration of the extract.Alocasia macrorrhiza aqueous extract exhibited proliferation inhibition and apoptosis effects on human hepatocellular carcinoma cells in vitro, inhibited hepatoma growth in vivo.Alocasia macrorrhiza extract has potential cytotoxic and apoptotic effect on human hepatocellular carcinoma cells and inhibits hepatoma growth in vivo, its mechanism of action might be associated with the inhibition of DNA synthesis, cell cycle (G(0)/G(1)) arrest, apoptosis induction through up-regulation the mRNA and protein expressions of PPARγ, Rb, Bax and capase-3genes and down-regulation of the expressions of Cyclin D1 and Bcl-2 genes.",
        "keywords": [
            "apoptosis",
            "growth inhibition",
            "alocasia macrorrhiza",
            "cytotoxicity",
            "hepatoma"
        ],
        "authors": [
            {
                "name": "Shengtao Fang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Caiyu Lin",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Quanbo Zhang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Li Wang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Ping Lin",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Xiujie Wang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            }
        ],
        "venue": "Journal of ethnopharmacology",
        "year": 2012
    },
    "rUCablXB": {
        "id": "rUCablXB",
        "title": "Growth inhibition and apoptotic effect of alpha-eleostearic acid on human breast cancer cells.",
        "abstract": "Alpha-eleostearic acid (α-ESA) is a natural and biologically active compound which possesses potent antioxidant and anti-tumor activity. The purpose of this study was to confirm the anticancer activity of α-ESA against human breast cancer cells and to further elucidate its mechanism of activity. Human breast cancer cells and normal liver cells were used for in-vitro tests of the anticancer activity of α-ESA, including cytotoxicity, colony formation inhibition, EdU incorporation, AO/EB staining of apoptotic cells, cell cycle distribution through flow cytometry, and PPARγ, p21, Bax, p53, and caspase-3 mRNA expressions through RT-PCR. After α-ESA treatment, the proliferation, colony formation, and EdU labeling indices of cancer cells decreased (p < 0.05), while the AO/EB-stained apoptotic cells increased (p < 0.05). By FCM analysis, the apoptotic indices increased (p < 0.01), and the cell population decreased in S phase (p < 0.01) and increased in G(2)/M phase (p < 0.05) in α-ESA treated cancer cells. RT-RCR showed that α-ESA significantly increased the expression levels of PPARγ, p21, Bax, p53, and caspase-3 mRNA. The findings in these studies suggested that α-ESA exhibited a potential cytotoxicity and apoptosis induction effect on human breast cancer cells, with little effect on normal cells at certain concentrations. The mechanism for such effects might be associated with the inhibition of DNA synthesis, induction of apoptosis, and cell cycle arrest of cancer cells through up-regulation of PPARγ, p21, Bax, p53, and caspase-3 expressions.",
        "keywords": [
            "alpha-eleostearic acidbreast cancer cells � proliferation inhibitionapoptosis induction"
        ],
        "authors": [
            {
                "name": "Tingting Zhang",
                "org": "Laboratory of Geriatrics, State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University, Chengdu, 610041 China"
            },
            {
                "name": "Yanping Gao",
                "org": "Laboratory of Geriatrics, State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University, Chengdu, 610041 China"
            },
            {
                "name": "Yu Mao",
                "org": "Ethnic Pharmaceutical Institute, Southwest University for Nationalities, Chengdu, 610041 China"
            },
            {
                "name": "Quanbo Zhang",
                "org": "Laboratory of Geriatrics, State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University, Chengdu, 610041 China"
            },
            {
                "name": "Caiyu Lin",
                "org": "Laboratory of Geriatrics, State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University, Chengdu, 610041 China"
            },
            {
                "name": "Ping Lin",
                "org": "Laboratory of Geriatrics, State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University, Chengdu, 610041 China"
            },
            {
                "name": "Jie Zhang",
                "org": "Laboratory of Geriatrics, State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University, Chengdu, 610041 China"
            },
            {
                "name": "Xiujie Wang",
                "org": "Laboratory of Geriatrics, State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University, Chengdu, 610041 China"
            }
        ],
        "venue": "Journal of natural medicines",
        "year": 2012
    },
    "Y6bgm5uj": {
        "id": "Y6bgm5uj",
        "title": "Interleukin 23 regulates proliferation of lung cancer cells in a concentration-dependent way in association with the interleukin-23 receptor.",
        "abstract": "A proinflammatory cytokine, interleukin 23 (IL-23), plays a role in tumor progression by inducing inflammation in the tumor microenvironment, although there is debate about its role in carcinogenesis. Direct effects of IL-23 on tumor cells have been reported rarely, and contradictory effects have been observed. Here, we studied such effects of IL-23 in lung cancer cells in vitro and in vivo and explored the underlying mechanism. We found IL-23 receptor expression in tissues from lung adenocarcinoma and small cell carcinoma but not in lung squamous cell carcinoma tissue. Interestingly, different concentrations of IL-23 had opposite effects in the same types of cells. We confirmed that the different effects could be explained by differences in binding to the IL-23 receptor (subunits IL-23r and IL-12Rβ1). Low concentrations of IL-23 promoted the proliferation of IL-23 receptor-positive A549 and SPCA-1 lung cancer cells by binding to IL-23r, whereas high concentrations of IL-23 inhibited proliferation of these cells by binding to both IL-23r and IL-12Rβ1. In contrast, IL-23 had no effect on IL-23 receptor-negative SK-MES-1 cells. IL-23 regulated the growth of human lung cancer cells through its effects on STAT3 expression and phosphorylation in a concentration-dependent way; the Ki-67 gene was involved in these processes. Our findings demonstrate for the first time that IL-23 affects the proliferation of IL-23 receptor-positive lung cancer cells and that this effect is dependent on the IL-23 concentration. This can explain at least part of the inconsistent reports on the role of IL-23 in the progression of carcinogenesis.",
        "keywords": [],
        "authors": [
            {
                "name": "Jun Li",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Le Zhang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Yuyan Wei",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Kai Li",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Lugang Huang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Sen Zhang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Bo Gao",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Xiujie Wang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Ping Lin",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            }
        ],
        "venue": "Carcinogenesis",
        "year": 2013
    },
    "VsbjMsRT": {
        "id": "VsbjMsRT",
        "title": "Forkhead box P3 in human airway regulatory T cells is regulated by suppressor of cytokine signaling",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "f lan",
                "org": ""
            },
            {
                "name": "nan zhang",
                "org": ""
            },
            {
                "name": "jinzhong zhang",
                "org": ""
            },
            {
                "name": "olga krysko",
                "org": ""
            },
            {
                "name": "qiang zhang",
                "org": ""
            },
            {
                "name": "junming xian",
                "org": ""
            },
            {
                "name": "lara derycke",
                "org": ""
            },
            {
                "name": "yijun qi",
                "org": ""
            },
            {
                "name": "k li",
                "org": ""
            },
            {
                "name": "shizhong liu",
                "org": ""
            },
            {
                "name": "peng lin",
                "org": ""
            },
            {
                "name": "claus bachert",
                "org": ""
            }
        ],
        "venue": "Allergy",
        "year": 2013
    },
    "s99IqzRi": {
        "id": "s99IqzRi",
        "title": "Morusin inhibits human cervical cancer stem cell growth and migration through attenuation of NF-κB activity and apoptosis induction.",
        "abstract": "Cancer stem cells (CSCs) are believed to be responsible for tumor metastasis, recurrence, and high mortality of cancer patients due to their high tumorigenicity resistance to chemo-radiotherapy. Morusin possesses anti-cancer activity through attenuation of NF-κB activity, which is up-regulated in cancer stem cells. The purpose of this study is to confirm the growth and migration inhibition effect of morusin on human cervical CSCs, and to clarify its partial mechanism of activity. Human cervical CSCs were enriched using non-adhesive culture system. Their stemness characteristics were identified with tumor sphere formation, self-renewal, toluidine blue staining, migration assays, RT-PCR analysis, and immunofluorescence staining of putative stem cell markers, Oct4, SOX2, and ALDH1; the epithelial-to-mesenchymal (EMT) transition markers and relevant transcription factors were evaluated with Western blotting. The growth and migration inhibition effects of morusin on human cervical CSCs were tested by cell proliferation, tumor sphere formation, and transwell assay; apoptotic death of human cervical CSCs in response to morusin was measured with DAPI staining, apoptotic DNA fragmentation; NF-κBp65, Bcl-2, Bax, and caspase-3 protein expressions were detected through Western blotting. Under this non-adhesive culture system, typical tumor spheres appeared within 5-7 days, the tumor sphere formation, self-renewal, and cell migration, expressions of putative stem cell markers, EMT markers, and relevant transcription factors of the tumor sphere cells were increased significantly. After morusin treatment, the proliferation, tumor sphere formation, and migration of human cervical CSCs were decreased significantly, DAPI-stained apoptotic cells increased, apoptotic DNA fragmentations formed evidently; the expression levels of NF-κBp65 and Bcl-2 decreased significantly, Bax, and caspase-3 increased significantly in a dose-dependent manner. Using the non-adhesive culture system, human cervical CSCs were enriched and expanded. Morusin has the potential to target and kill CSCs, and can inhibit human cervical growth and migration through NF-κB attenuation mediated apoptosis induction.",
        "keywords": [
            "Cervical cancer",
            "Cancer stem cells",
            "Cancer stem markers",
            "Morusin",
            "Growth inhibition",
            "Apoptosis"
        ],
        "authors": [
            {
                "name": "Li Wang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Huijie Guo",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Liuqi Yang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Lihua Dong",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Caiyu Lin",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Ping Lin",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Xiujie Wang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            }
        ],
        "venue": "Molecular and cellular biochemistry",
        "year": 2013
    },
    "3kU6cDMA": {
        "id": "3kU6cDMA",
        "title": "Cytoplasmic expression, antibody production, and characterization of the novel zinc finger protein 637.",
        "abstract": "Zinc finger protein 637 (zfp637), belonging to the Kruppel-like protein family, comprises one atypical C(2)H(2) and six consecutive typical zinc finger motifs. Based on the structural characterization of zfp637 and its location in the cell nucleus, we predict that zfp637 might function as a DNA-binding protein to regulate gene transcription. However, the absence of both a purified zfp637 protein and any commercial antibody for detecting it in cells and tissues has limited functional studies of zfp637 to date. Here, we developed and optimized an expression system by fusing zfp637 with glutathione S-transferase (GST) to achieve a maximal yield of soluble GST-zfp637 fusion protein in Escherichia coli BL21(DE3) cells. The yield was about 10 mg/l of the original bacterial culture. The recombinant GST-zfp637 fusion protein was purified and used for polyclonal antibody production in rabbits. In addition, we developed a method to remove the anti-GST antibody component and obtained a highly purified anti-zfp637 antibody, as demonstrated by an enzyme-linked immunosorbent assay. Western blotting showed that the anti-zfp637 antibody recognized not only the recombinant zfp637 protein but also endogenous zfp637 in several cell lines. The protein was localized mainly in the cell nucleus by immunofluorescence and immunohistochemistry. The expression levels of zfp637 mRNA and protein were significantly increased in NIH3T3 cells treated with 200 μM of H(2)O(2) in a time-dependent manner. The recombinant GST-zfp637 fusion protein and our purified anti-zfp637 antibody will help in elucidating the function of zfp637.",
        "keywords": [
            "zfp637",
            "recombinant protein",
            "cytoplasmic expression",
            "anti-zfp637-specific antibody",
            "oxidative stress"
        ],
        "authors": [
            {
                "name": "Kai Li",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Yuyan Wei",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Jun Li",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Bo Gao",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Lugang Huang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Ping Lin",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Yuquan Wei",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            }
        ],
        "venue": "Applied microbiology and biotechnology",
        "year": 2013
    },
    "fIPsWQn1": {
        "id": "fIPsWQn1",
        "title": "Urotensin II Protects Cardiomyocytes from Apoptosis Induced by Oxidative Stress through the CSE/H2S Pathway",
        "abstract": "",
        "keywords": [
            "apoptosis"
        ],
        "authors": [
            {
                "name": "hui gong",
                "org": ""
            },
            {
                "name": "zhidan chen",
                "org": ""
            },
            {
                "name": "xiaoyi zhang",
                "org": ""
            },
            {
                "name": "yang li",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "ying chen",
                "org": ""
            },
            {
                "name": "yingjiong ding",
                "org": ""
            },
            {
                "name": "guoping zhang",
                "org": ""
            },
            {
                "name": "chunjie yang",
                "org": ""
            },
            {
                "name": "yichun zhu",
                "org": ""
            },
            {
                "name": "yunzeng zou",
                "org": ""
            }
        ],
        "venue": "International Journal of Molecular Sciences",
        "year": 2015
    },
    "fdC5ZMFb": {
        "id": "fdC5ZMFb",
        "title": "Effects of Bifidobacterium Breve Feeding Strategy and Delivery Modes on Experimental Allergic Rhinitis Mice",
        "abstract": "",
        "keywords": [
            "nasal mucosa",
            "antibodies"
        ],
        "authors": [
            {
                "name": "jianjun ren",
                "org": "sichuan university"
            },
            {
                "name": "zhao yu",
                "org": "sichuan university"
            },
            {
                "name": "fengling yang",
                "org": "sichuan university"
            },
            {
                "name": "dan lv",
                "org": "sichuan university"
            },
            {
                "name": "shi hung",
                "org": "sichuan university"
            },
            {
                "name": "jie zhang",
                "org": "sichuan university"
            },
            {
                "name": "ping lin",
                "org": "sichuan university"
            },
            {
                "name": "shixi liu",
                "org": "sichuan university"
            },
            {
                "name": "nan zhang",
                "org": "ghent university"
            },
            {
                "name": "claus bachert",
                "org": "ghent university"
            }
        ],
        "venue": "PLOS ONE",
        "year": 2015
    },
    "nChgyZaf": {
        "id": "nChgyZaf",
        "title": "AMPK activation protects cells from oxidative stress‐induced senescence via autophagic flux restoration and intracellular NAD+ elevation",
        "abstract": "Abstract AMPK activation is beneficial for cellular homeostasis and senescence prevention. However, the molecular events involved in AMPK activation are not well defined. In this study, we addressed the mechanism underlying the protective effect of AMPK on oxidative stress-induced senescence. The results showed that AMPK was inactivated in senescent cells. However, pharmacological activation of AMPK by metformin and berberine significantly prevented the development of senescence and, accordingly, inhibition of AMPK by Compound C was accelerated. Importantly, AMPK activation prevented hydrogen peroxide-induced impairment of the autophagic flux in senescent cells, evidenced by the decreased p62 degradation, GFP-RFP-LC3 cancellation, and activity of lysosomal hydrolases. We also found that AMPK activation restored the NAD(+) levels in the senescent cells via a mechanism involving mostly the salvage pathway for NAD(+) synthesis. In addition, the mechanistic relationship of autophagic flux and NAD(+) synthesis and the involvement of mTOR and Sirt1 activities were assessed. In summary, our results suggest that AMPK prevents oxidative stress-induced senescence by improving autophagic flux and NAD(+) homeostasis. This study provides a new insight for exploring the mechanisms of aging, autophagy and NAD(+) homeostasis, and it is also valuable in the development of innovative strategies to combat aging.",
        "keywords": "",
        "authors": [
            {
                "name": "Xiaojuan Han",
                "org": "Lab for Aging Research, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center for Biotherapy, Chengdu, China"
            },
            {
                "name": "Haoran Tai",
                "org": "Lab for Aging Research, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center for Biotherapy, Chengdu, China"
            },
            {
                "name": "Xiaobo Wang",
                "org": "Lab for Aging Research, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center for Biotherapy, Chengdu, China"
            },
            {
                "name": "Zhe Wang",
                "org": "Lab for Aging Research, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center for Biotherapy, Chengdu, China"
            },
            {
                "name": "Jiao Zhou",
                "org": "Lab for Aging Research, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center for Biotherapy, Chengdu, China"
            },
            {
                "name": "Xiawei Wei",
                "org": "Lab for Aging Research, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center for Biotherapy, Chengdu, China"
            },
            {
                "name": "Yi Ding",
                "org": "Lab for Aging Research, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center for Biotherapy, Chengdu, China"
            },
            {
                "name": "Hui Gong",
                "org": "Lab for Aging Research, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center for Biotherapy, Chengdu, China"
            },
            {
                "name": "Chunfen Mo",
                "org": "Lab for Aging Research, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center for Biotherapy, Chengdu, China"
            },
            {
                "name": "Jie Zhang",
                "org": "Lab for Aging Research, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center for Biotherapy, Chengdu, China"
            },
            {
                "name": "Jianqiong Qin",
                "org": "Lab for Aging Research, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center for Biotherapy, Chengdu, China"
            },
            {
                "name": "Yuanji Ma",
                "org": "Center of Infectious Diseases, West China Hospital, Sichuan University, Chengdu, China"
            },
            {
                "name": "Ning Huang",
                "org": "Lab for Aging Research, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center for Biotherapy, Chengdu, China"
            },
            {
                "name": "Rong Xiang",
                "org": "Department of Clinical Medicine, Medical School of Nankai University, Tianjin, China"
            },
            {
                "name": "Hengyi Xiao",
                "org": "Lab for Aging Research, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center for Biotherapy, Chengdu, China"
            }
        ],
        "venue": "Aging Cell",
        "year": 2016
    },
    "vgHyABiF": {
        "id": "vgHyABiF",
        "title": "Phonological Knowledge beyond the Lexicon in Taiwanese Double Reduplication",
        "abstract": "Recent studies on productivity have shown that native speakers' phono- logical knowledge not only includes statistical patterning of irregularities reflected in the lexicon, but also patterns that cannot be gleaned from the lexicon. This is demonstrated in speakers' analytical bias towards abstract phonological represen- tations (Davidson 2005) and perceptually motivated phonological scales (Zuraw 2007), as well as their difficulties with exceptionless opaque patterns in wug tests (Zhang et al., to appear). Based on the results of a wug test, we show in this paper that the tone pattern in Taiwanese double reduplication is a case in which the speakers' knowledge is a combination of more than, less than, and exactly what their lexicon informs them of. We also provide a stochastic OT grammar based on the dual listing/generation model of Zuraw (2000) to account for our wug test results.",
        "keywords": [
            "taiwanese tone sandhi",
            "produc- tivity",
            "wug test",
            "double reduplication",
            "opacity",
            "stochastic ot",
            "lexical listing"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "University of Kansas"
            },
            {
                "name": "Yuwen Lai",
                "org": "University of Kansas"
            }
        ],
        "venue": "",
        "year": 0
    },
    "WT8M0vVl": {
        "id": "WT8M0vVl",
        "title": "Wug-Testing the \"Tone Circle\" in Taiwanese",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "University of Kansas"
            },
            {
                "name": "Yuwen Lai",
                "org": "University of Kansas"
            },
            {
                "name": "Craig Turnbull-Sailor",
                "org": "University of Kansas"
            }
        ],
        "venue": "",
        "year": 0
    },
    "p9FptKFw": {
        "id": "p9FptKFw",
        "title": "Testing the Role of Phonetic Naturalness in Mandarin Tone Sandhi",
        "abstract": "It has long been noted that phonological patterning is influenced by phonetic factors. But phonologists diverge on whether phonetic motivations take effect in synchronic or diachronic phonology. This article aims to tease apart the two theories by investigating native Mandarin speakers' applications of two tone sandhi processes to novel words: the phonetically motivated contour reduction 213￻21/__T (T� 213) and the neutralizing 213￻35/__213 whose phonetic motivations are less clear. Twenty Mandarin subjects were asked to produce two monosyllables they heard as disyllabic words. Five groups of disyllabic words were tested: AO-AO (AO=actual occurring morpheme) where the disyllable is also a real word, AO-AO' where the disyllable is non- occurring, AO-AG (AG=accidental gap in Mandarin lexicon — legal syllable and tone but non-existent combination), AG-AO, and AG-AG. The first syllable is always 213, and the second syllable has one of the four tones in Mandarin. Results show that speakers apply the phonetically more natural 213￻21 sandhi more quickly and with greater accuracy than the 213￻35 sandhi. Theoretically, the study supports the direct relevance of phonetics to synchronic phonology by showing that there is a psychological advantage to phonetically natural patterns. Methodologically, it complements existing research paradigms that test the nature of the phonology-phonetics relationship, e.g., the study of phonological acquisition and the artificial language paradigm; when extended to other Chinese dialects, it can also provide insights into the long-standing mystery of how Chinese speakers internalise complicated tone sandhi patterns that sometimes involve opacity, near-neutralization, and syntactic dependency.",
        "keywords": [
            "working paper"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Yuwen Lai",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2006
    },
    "M5Xo34JN": {
        "id": "M5Xo34JN",
        "title": "Testing the role of phonetic knowledge in Mandarin tone sandhi",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Yuwen Lai",
                "org": ""
            }
        ],
        "venue": "Phonology",
        "year": 2010
    },
    "6Lymw5j5": {
        "id": "6Lymw5j5",
        "title": "Selling or Subscribing Software under Quality Uncertainty and Network Externality Effect",
        "abstract": "We examine the optimal way for a software vendor to license software: perpetual license at a posted price, subscription contract that subscribers receive automatic updates for periodic payment, or a hybrid approach that involves both. By addressing such specific issues in the software market as network effects, quality uncertainty, upgrade compatibility, and the vendor's ability to commit to future prices in a dynamic environment, we demonstrate how a software vendor can manage the trade-offs of perpetual licensing and subscription to optimize profit, as well as the corresponding welfare effect on consumers. Though the subscription model helps the vendor lock in consumers so as to increase profit when there is a great uncertainty associated with the next version software, it destroys the path dependence in creating network externalities.Therefore, when the network effect is sufficiently large, it is more profitable for a software vendor to provide both perpetual licensing and subscription.",
        "keywords": [
            "quality uncertainty",
            "network effect",
            "subscription contract",
            "next version software",
            "software vendor",
            "perpetual license",
            "vendor lock",
            "network externality",
            "network externality effect",
            "subscription model",
            "software market",
            "perpetual licensing",
            "software quality",
            "profitability",
            "uncertainty",
            "schedules"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Abraham Seidmann",
                "org": ""
            }
        ],
        "venue": "HICSS",
        "year": 2010
    },
    "SsgGzq1s": {
        "id": "SsgGzq1s",
        "title": "Introduction to the special issue on \\\"information issues in supply chain and in service system design\\\"",
        "abstract": "",
        "keywords": [
            "supply chain",
            "service system"
        ],
        "authors": [
            {
                "name": "Abraham Seidmann",
                "org": "W. E. Simon Graduate School of Business Administration, University of Rochester, United States"
            },
            {
                "name": "Yabing Jiang",
                "org": "Graduate School of Business Administration, Fordham University, United States"
            },
            {
                "name": "Jie Zhang",
                "org": "College of Business, University of Texas at Arlington, United States"
            }
        ],
        "venue": "Decision Support Systems",
        "year": 2011
    },
    "0vMP4PDI": {
        "id": "0vMP4PDI",
        "title": "Introduction to the Information Issues in Supply Chain and in Service System Design Minitrack",
        "abstract": "Cognitive effort and knowledge sharing play a critical role in the successful completion of knowledge intensive collaborative tasks. Such tasks require extensive coordination and sense making to facilitate joint problem solving and the creation of shared mental models. Furthermore, multiple heads often come with multiple stakes and perspectives, which can lead to conflict and often require trust building and negotiation. Therefore, the cognitive load involved in collaborative tasks is likely to be higher than in individual tasks, and requires special attention when designing collaboration support. Understanding cognitive load and cognitive activities involved in collaboration may offer insight into design principles that enable efficient and effective use of cognitive capacity. The intent of this minitrack is to provide an outlet for such research and encourage research that explores the individual cognitive perspective when studying collaboration.",
        "keywords": [
            "collaborative task",
            "cognitive activity",
            "knowledge sharing",
            "knowledge intensive collaborative task",
            "Service System Design Minitrack",
            "collaboration support",
            "cognitive effort",
            "cognitive load",
            "Information Issues",
            "individual task",
            "Supply Chain",
            "cognitive capacity",
            "individual cognitive perspective"
        ],
        "authors": [
            {
                "name": "Abraham Seidmann",
                "org": ""
            },
            {
                "name": "Yabing Jiang",
                "org": ""
            },
            {
                "name": "Zhang, Jie",
                "org": ""
            }
        ],
        "venue": "HICSS '12 Proceedings of the 2012 45th Hawaii International Conference on System Sciences",
        "year": 2012
    },
    "LkfB5eAG": {
        "id": "LkfB5eAG",
        "title": "Process Monitoring Using Non-Linear Principal Component Analysis",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Department of Chemical and Process Engineering, University of Newcastle, Newcastle upon Tyne NE1 7RU, U.K. Tel: +44-191-2227234 Fax: +44-191-2225292"
            },
            {
                "name": "A.J. Morris",
                "org": "Department of Chemical and Process Engineering, University of Newcastle, Newcastle upon Tyne NE1 7RU, U.K. Tel: +44-191-2227234 Fax: +44-191-2225292"
            },
            {
                "name": "E.B. Martin",
                "org": "Department of Engineering Mathematics, University of Newcastle, Newcastle upon Tyne NE1 7RU, U.K. Tel: +44-191-2227234 Fax: +44-191-2225292"
            }
        ],
        "venue": "IFAC Proceedings Volumes",
        "year": 1996
    },
    "cSVhBB9M": {
        "id": "cSVhBB9M",
        "title": "Nonlinear Process Modelling using Dynamic Neuro-Fuzzy Networks",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Centre for Process Analysis Chemometrics and Control, University of Newcastle, Newcastle upon Tyne, NE1 7RU, U. K. Phone: 44-191-222 7342 Fax: 44-191-2225292"
            },
            {
                "name": "A.J. Morris",
                "org": "Centre for Process Analysis Chemometrics and Control, University of Newcastle, Newcastle upon Tyne, NE1 7RU, U. K. Phone: 44-191-222 7342 Fax: 44-191-2225292"
            }
        ],
        "venue": "IFAC Proceedings Volumes",
        "year": 1997
    },
    "ogftBIch": {
        "id": "ogftBIch",
        "title": "Long Range Predictive Control of Nonlinear Processes Based on Recurrent Neuro-Fuzzy Network Models",
        "abstract": "A recurrent neuro-fuzzy network-based nonlinear long range model predictive control strategy is proposed in this paper. The\n process operation is partitioned into several fuzzy operating regions. Within each region, a local linear model is used to\n model the process. The global model output is obtained through the centre of gravity defuzzification. Based upon a neuro-fuzzy\n network model, a nonlinear model-based predictive controller can be developed by combining several local linear model-based\n predictive controllers which usually have analytical solutions. This strategy avoids the time consuming numerical optimisation\n procedure, and the uncertainty in convergence to the global optimum which are typically seen in conventional nonlinear model-based\n predictive control strategies. Furthermore, control actions obtained based on local incremental models contain integration\n actions which can nat-urally eliminate static control offsets. The technique is demonstrated by an application to the modelling\n and control of liquid level in a water tank.  ",
        "keywords": [
            "neural networks",
            "fuzzy models",
            "model-based predictive control",
            "long range prediction",
            "neuro-fuzzy networks",
            "process control"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Centre for Process Analytics and Control Technology, Department of Chemical & Process Engineering, University of Newcastle, Newcastle upon Tyne, UK GB"
            },
            {
                "name": "A. J. Morris",
                "org": "Centre for Process Analytics and Control Technology, Department of Chemical & Process Engineering, University of Newcastle, Newcastle upon Tyne, UK GB"
            }
        ],
        "venue": "Neural Computing and Applications",
        "year": 2000
    },
    "mXR68YTa": {
        "id": "mXR68YTa",
        "title": "Inferential feedforward control of a distillation column",
        "abstract": "",
        "keywords": [
            "chemical engineering",
            "distillation",
            "feedforward",
            "robustness",
            "chemical processes",
            "process control",
            "stability",
            "control systems",
            "nonlinear dynamics",
            "temperature control",
            "distillation column",
            "robust control",
            "temperature measurement",
            "feedforward control"
        ],
        "authors": [
            {
                "name": "jie zhang",
                "org": "university of newcastle"
            },
            {
                "name": "r agustriyano",
                "org": ""
            }
        ],
        "venue": "american control conference",
        "year": 2001
    },
    "FdtShZpF": {
        "id": "FdtShZpF",
        "title": "Multi-objective optimal control of batch processes using recurrent neuro-fuzzy networks",
        "abstract": "",
        "keywords": [
            "membership function",
            "optimal control",
            "neural networks",
            "neural network",
            "neuro fuzzy",
            "polymers",
            "chemical industry",
            "batch reactor",
            "input output",
            "predictive models",
            "learning artificial intelligence",
            "process control",
            "chemical analysis",
            "chemical reactors",
            "multi objective optimization",
            "inductors",
            "batch process",
            "prediction model"
        ],
        "authors": [
            {
                "name": "jie zhang",
                "org": "newcastle university"
            }
        ],
        "venue": "international symposium on neural networks",
        "year": 2003
    },
    "HerngCZ1": {
        "id": "HerngCZ1",
        "title": "Improved inferential feedback control through combining multiple PCR models",
        "abstract": "",
        "keywords": [
            "feedback control",
            "testing",
            "chemical engineering",
            "regression analysis",
            "software performance",
            "chemical industry",
            "distillation column",
            "feedback",
            "neural networks",
            "cross validation",
            "principal component analysis",
            "principal component regression",
            "principal component",
            "temperature measurement"
        ],
        "authors": [
            {
                "name": "mohamed h ahmed",
                "org": "university of newcastle"
            },
            {
                "name": "jie zhang",
                "org": "university of newcastle"
            }
        ],
        "venue": "",
        "year": 2003
    },
    "iolq5RLg": {
        "id": "iolq5RLg",
        "title": "A Neural Network Modeling Method for Batch Process",
        "abstract": "\n For the production of high quality chemicals batch manufacture plays an important role. Since some parameters of a batch chemical\n reaction are difficult to measure with conventional instruments, Artificial Neural Network (ANN) model has become a useful\n tool for the estimation of chemical reaction indexes. Data restructuring is an effective method for improving properties and\n accuracy of the ANN model. This paper constructed an ANN model for estimating the number-average molecular weight and polydispersity\n in batch polymerization process and presented the method of training data restructuring. The results were satisfactory.\n \n ",
        "keywords": [
            "molecular weight",
            "chemical reaction",
            "indexation",
            "batch process",
            "neural network model",
            "artificial neural network"
        ],
        "authors": [
            {
                "name": "Yi Liu",
                "org": "Institution of Process Control Engineering, Department of Automation, Tsinghua University, Beijing, 100084 China"
            },
            {
                "name": "Xianhui Yang",
                "org": "Institution of Process Control Engineering, Department of Automation, Tsinghua University, Beijing, 100084 China"
            },
            {
                "name": "Jie Zhang",
                "org": "Centre for Process Analytics and Control Technology, School of Chemical Engineering and Advanced Materials, University of Newcastle, Newcastle upon Tyne, NE1 7RU U.K"
            }
        ],
        "venue": "ISNN (2)",
        "year": 2004
    },
    "s1iLb89o": {
        "id": "s1iLb89o",
        "title": "Integrated batch-to-batch control and within batch control of batch processes using neural network models",
        "abstract": "",
        "keywords": [
            "neural network model",
            "iterative methods",
            "optimal control",
            "batch process",
            "neural nets",
            "iterative learning control",
            "adaptive control",
            "process control"
        ],
        "authors": [
            {
                "name": "jie zhang",
                "org": "newcastle university"
            }
        ],
        "venue": "",
        "year": 2004
    },
    "ml7lxBKo": {
        "id": "ml7lxBKo",
        "title": "An integrated batch-to-batch iterative learning control and within batch control strategy for batch processes",
        "abstract": "An integrated batch-to-batch iterative learning control (ILC) and within batch on-line shrinking horizon model predictive control (SHMPC) strategy for the tracking control of product qualities in batch processes is proposed. ILC is used for batch-to-batch control based on a batch-wise linear time-varying (LTV) perturbation model and the convergence of batch-wise tracking error under ILC is guaranteed. On-line SHMPC within a batch can reduce the effects of disturbances immediately and improve the performance of the current batch run. The on-line model prediction can be also obtained based on the batch-wise LTV model. The integrated control strategy can complement both methods to obtain good performance of tracking control. The proposed strategy is illustrated on a simulated batch polymerization process. © 2005 AACC.",
        "keywords": [
            "model predictive control",
            "automation",
            "iterative methods",
            "chemical engineering",
            "linear regression",
            "iterative learning control",
            "batch process",
            "trajectory",
            "adaptive control",
            "noise measurement",
            "predictive control",
            "error correction",
            "process control",
            "automatic control",
            "least squares approximation",
            "predictive models"
        ],
        "authors": [
            {
                "name": "Zhihua Xiong",
                "org": "Tsinghua University(Tsinghua University,Tsinghua Univ,Tsinghua Univ.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Newcastle University, United Kingdom(University of Newcastle upon Tyne,University of Newcastle,University of Newcastle Upon Tyne,Newcastle University),Newcastle,United Kingdom"
            },
            {
                "name": "Xiong Wang",
                "org": "Tsinghua University(Tsinghua University,Tsinghua Univ,Tsinghua Univ.),Beijing,China"
            },
            {
                "name": "Yongmao Xu",
                "org": "Tsinghua University(Tsinghua University,Tsinghua Univ,Tsinghua Univ.),Beijing,China"
            }
        ],
        "venue": "Proceedings of the American Control Conference",
        "year": 2005
    },
    "jMfffZ1v": {
        "id": "jMfffZ1v",
        "title": "Optimal Control of Fed-Batch Processes Based on Multiple Neural Networks",
        "abstract": "The performance of empirical model based fed-batch process optimal control is strongly affected by the model prediction reliability at the end-point of a batch. An optimal control profile calculated from an empirical model may not give the best performance when applied to the actual process due to model-plant mismatches. To tackle this issue, a new method for improving the reliability of fed-batch process optimal control by incorporating model prediction confidence bounds is proposed. Multiple neural networks (MNN) are used to build an empirical model of fed-batch process based on process operation data. Model prediction confidence bounds are calculated based on predictions of all component networks in an MNN model and the model prediction confidence bound at the end-point of a batch is incorporated into the optimization objective function. The modified objective function penalizes wide prediction confidence bounds in order to obtain a reliable optimal control profile. The non-linear optimization problem based on MNN with augmented objective function is solved by iterative dynamic programming. The proposed control strategy is illustrated on a simulated fed-batch ethanol fermentation process. The results demonstrate that the optimal control profile calculated from the proposed approach is reliable in the sense that its performance degradation is limited when applied to the actual process.",
        "keywords": [
            "multiple neural networks",
            "batch processes",
            "optimal control",
            "confidence bounds"
        ],
        "authors": [
            {
                "name": "Zhihua Xiong",
                "org": "Centre for Process Analytics and Control Technology, School of Chemical Engineering and Advanced Materials, University of Newcastle, UK NE1 7RU"
            },
            {
                "name": "Jie Zhang",
                "org": "Centre for Process Analytics and Control Technology, School of Chemical Engineering and Advanced Materials, University of Newcastle, UK NE1 7RU"
            }
        ],
        "venue": "Appl. Intell.",
        "year": 2005
    },
    "5tUZYopq": {
        "id": "5tUZYopq",
        "title": "Modelling and multi-objective optimal control of batch processes using recurrent neuro-fuzzy networks",
        "abstract": "In this paper, the modelling and multi-objective optimal control of batch processes, using a recurrent neuro-fuzzy network,\n are presented. The recurrent neuro-fuzzy network, forms a “global” nonlinear long-range prediction model through the fuzzy\n conjunction of a number of “local” linear dynamic models. Network output is fed back to network input through one or more\n time delay units, which ensure that predictions from the recurrent neuro-fuzzy network are long-range. In building a recurrent\n neural network model, process knowledge is used initially to partition the processes non-linear characteristics into several\n local operating regions, and to aid in the initialisation of corresponding network weights. Process operational data is then\n used to train the network. Membership functions of the local regimes are identified, and local models are discovered via network\n training. Based on a recurrent neuro-fuzzy network model, a multi-objective optimal control policy can be obtained. The proposed\n technique is applied to a fed-batch reactor.",
        "keywords": [
            "multi-objective optimisation.",
            "batch processes",
            "optimal control",
            "neural networks",
            "prediction model",
            "recurrent neural network",
            "neuro fuzzy",
            "membership function",
            "neural network",
            "batch reactor",
            "network model",
            "batch process",
            "multi objective optimization"
        ],
        "authors": [
            {
                "name": "jie",
                "org": "university of newcastle"
            },
            {
                "name": "zhang",
                "org": "university of newcastle"
            }
        ],
        "venue": "International Journal of Automation and Computing",
        "year": 2006
    },
    "OJdLNraI": {
        "id": "OJdLNraI",
        "title": "Fault detection of dynamic processes using a simplified monitoring-specific CVA state space approach",
        "abstract": "There have been much reported successes with the use of state space models for process identification, control and monitoring of dynamic processes with several different approaches to deriving the state variables and a few variants of the state space model representation having been documented over the years. Typically the form of statespace model adopted is one that requires the estimation of five matrices to fully parameterize the model. This paper proposes a simplification of the state-space model for the specific purpose of process monitoring. The simplification of the representation achieved via a modified definition of the past vector of inputs and output, facilitates a simpler and more efficiently estimation of a reduced set of state space matrices. The proposed approach in conjunction with a devised filtering method gives improved fault detection performance over the established state space monitoring methods and other multivariate statistical methods.",
        "keywords": [
            "cva",
            "dynamic models",
            "state space modeling",
            "process monitoring",
            "fault detection",
            "state space",
            "state space model",
            "multivariate statistics"
        ],
        "authors": [
            {
                "name": "Shallon Stubbs",
                "org": "Centre for Process Analytics and Control Technology, School of Chemical Engineering and Advanced Materials, Newcastle University, Newcastle upon Tyne NE1 7RU, UK"
            },
            {
                "name": "Jie Zhang",
                "org": "Centre for Process Analytics and Control Technology, School of Chemical Engineering and Advanced Materials, Newcastle University, Newcastle upon Tyne NE1 7RU, UK"
            },
            {
                "name": "Julian Morris",
                "org": "Centre for Process Analytics and Control Technology, School of Chemical Engineering and Advanced Materials, Newcastle University, Newcastle upon Tyne NE1 7RU, UK"
            }
        ],
        "venue": "Computer Aided Chemical Engineering",
        "year": 2009
    },
    "p7CO5vZi": {
        "id": "p7CO5vZi",
        "title": "Performance Monitoring and Batch to Batch Control of Biotechnological Processes",
        "abstract": "This Chapter describes two approaches to ensuring the production quality of batch biotechnological processes. The first makes\n use of the multivariate statistical data analysis and multivariate statistical process control (MSPC) or better termed multivariate\n statistical process performance monitoring (MSPM). An industrial application is described to the interrogation of data from\n a reaction vessel producing an active pharmaceutical ingredient (API) which enabled the realization of a better understanding\n of the factors causing the onset of an impurity formation to be obtained as well demonstrating the power of multivariate statistical\n data analysis techniques to provide an enhanced understanding of the process. In the second application, a simulation study\n of batch-to-batch iterative learning control strategy is presented where the batch control actions for the next batch are\n adjusted using the information obtained from current and previous batches. The control policy updating is calculated using\n a model linearized around a reference batch. In order to cope with process variations and disturbances, the reference batch\n can be taken as the immediate previous batch. After each batch, the newly obtained process operation data is added to the\n historical data base and an updated linearized model is re-identified. Since the control actions during different stages of\n a batch are usually correlated, it is proposed here that the linearized model can be identified from partial least square\n regression.\n ",
        "keywords": [],
        "authors": [
            {
                "name": "Julian Morris",
                "org": "Newcastle University Centre for Process Analytics and Control Technology, School of Chemical Engineering and Advanced Materials Newcastle upon Tyne NE1 7RU UK"
            },
            {
                "name": "Jie Zhang",
                "org": "Newcastle University Centre for Process Analytics and Control Technology, School of Chemical Engineering and Advanced Materials Newcastle upon Tyne NE1 7RU UK"
            }
        ],
        "venue": "",
        "year": 2009
    },
    "MpEb7dYB": {
        "id": "MpEb7dYB",
        "title": "Enhanced Predictive Modeling Using Multi Block Methods",
        "abstract": "Multi block PLS (MBPLS) models have been reported to handle the complexity of data which is difficult to anlayse with the conventional PLS models. However, the conventional MBPLS models do not offer improved predictive modeling in terms of prediction performance. A data partitioning method for enhanced predictive process modeling is proposed in this paper and is called Time-MBPLS. It enables data to be separated into blocks by different measuring time. Model parameters can be used to express contributions for all variables in a certain time period and it is possible to determine data blocking structures according to variable impacts on the quality variables. The proposed method is applied to the inferential estimation of a quality variable in a bio-production process. The results demonstrate that the proposed method can improve model prediction performance on the unseen testing data",
        "keywords": [
            "quality prediction",
            "time-mbpls",
            "mbpls",
            "batch processes",
            "process model",
            "production process",
            "prediction model",
            "batch process"
        ],
        "authors": [
            {
                "name": "Jeong Jin Hong",
                "org": "Centre for Process Analytics and Control Technology (CPACT), School of Chemical Engineering and Advanced Materials, Newcastle University, Newcastle upon Tyne, NE1 7RU, UK"
            },
            {
                "name": "Jie Zhang",
                "org": "Centre for Process Analytics and Control Technology (CPACT), School of Chemical Engineering and Advanced Materials, Newcastle University, Newcastle upon Tyne, NE1 7RU, UK"
            },
            {
                "name": "Julian Morris",
                "org": "Centre for Process Analytics and Control Technology (CPACT), School of Chemical Engineering and Advanced Materials, Newcastle University, Newcastle upon Tyne, NE1 7RU, UK"
            }
        ],
        "venue": "Computer Aided Chemical Engineering",
        "year": 2009
    },
    "dH3VJK7M": {
        "id": "dH3VJK7M",
        "title": "Reconstruction-based multivariate contribution analysis for fault isolation: A branch and bound approach",
        "abstract": "Identification of faulty variables is an important component of multivariate statistical process monitoring (MSPM); it provides crucial information for further analysis of the root cause of the detected fault. The main challenge is the large number of combinations of process variables under consideration, usually resulting in a combinatorial optimization problem. This paper develops a generic reconstruction based multivariate contribution analysis (RBMCA) framework to identify the variables that are the most responsible for the fault. A branch and bound (BAB) algorithm is proposed to efficiently solve the combinatorial optimization problem. The formulation of the RBMCA does not depend on a specific model, which allows it to be applicable to any MSPM model. We demonstrate the application of the RBMCA to a specific model: the mixture of probabilistic principal component analysis (PPCA mixture) model. Finally, we illustrate the effectiveness and computational efficiency of the proposed methodology through a numerical example and the benchmark simulation of the Tennessee Eastman process. © 2012 Elsevier Ltd. All rights reserved.",
        "keywords": [
            "branch and bound",
            "combinatorial optimization",
            "fault detection and isolation",
            "multivariate contribution analysis",
            "multivariate statistical process control"
        ],
        "authors": [
            {
                "name": "Bo He",
                "org": "Tsinghua University(Tsinghua University,Tsinghua Univ,Tsinghua Univ.),Beijing,China"
            },
            {
                "name": "Xianhui Yang",
                "org": "Tsinghua University(Tsinghua University,Tsinghua Univ,Tsinghua Univ.),Beijing,China"
            },
            {
                "name": "Tao Chen",
                "org": "University of Surrey(University of Surrey,Univ of Surrey),Surrey,United Kingdom"
            },
            {
                "name": "Jie Zhang",
                "org": "Newcastle University, United Kingdom(University of Newcastle upon Tyne,University of Newcastle,University of Newcastle Upon Tyne,Newcastle University),Newcastle,United Kingdom"
            }
        ],
        "venue": "Journal of Process Control",
        "year": 2012
    },
    "EqOnv2tk": {
        "id": "EqOnv2tk",
        "title": "Inferential estimation of kerosene dry point in refineries with varying crudes",
        "abstract": "A bootstrap aggregated model approach to the estimation of kerosene dry point in refineries with varying crudes is proposed in this paper. Using on-line measurements of process variables, the feed crude oil is classified into one of the three types: with more light component, with more middle component, and with more heavy component. Bootstrap aggregated neural networks are used in developing the on-line crude oil classifier. Historical process operation data are classified into these three groups. A bootstrap aggregated partial least square (PLS) regression model is developed for each data group corresponding to each type of feed crude oil. During on-line operation, the feed crude oil type is first estimated from on-line process measurements and then the corresponding bootstrap aggregated PLS model is invoked. The overall inferential estimation performance of the bootstrap aggregated PLS estimator integrated with feed crude oil classifier is significantly enhanced.",
        "keywords": [
            "inferential estimation",
            "bootstrap aggregated model",
            "crude distillation",
            "data-driven models"
        ],
        "authors": [
            {
                "name": "Chang Zhou",
                "org": "Department of Automation, Tsinghua University, Beijing 100084, China"
            },
            {
                "name": "Qiyue Liu",
                "org": "Department of Automation, Tsinghua University, Beijing 100084, China"
            },
            {
                "name": "Dexian Huang",
                "org": "TNList, Beijing 100084, China"
            },
            {
                "name": "Jie Zhang",
                "org": "School of Chemical Engineering and Advanced Materials, Newcastle University, Newcastle upon Tyne NE1 7RU, UK"
            }
        ],
        "venue": "Computer Aided Chemical Engineering",
        "year": 2012
    },
    "W8OU5JKV": {
        "id": "W8OU5JKV",
        "title": "Distillation control structure selection for energy efficient operations",
        "abstract": "",
        "keywords": [
            "exergy",
            "energy efficiency"
        ],
        "authors": [
            {
                "name": "f n osuolale",
                "org": "newcastle university"
            },
            {
                "name": "jie zhang",
                "org": "newcastle university"
            }
        ],
        "venue": "Chemical Engineering & Technology",
        "year": 2015
    },
    "OZAks4QT": {
        "id": "OZAks4QT",
        "title": "Iterative learning control of polyhydroxybutyrate production in a sequencing batch reactor",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Seyong Jung",
                "org": "newcastle university"
            },
            {
                "name": "Jie Zhang",
                "org": "newcastle university"
            },
            {
                "name": "Rui Oliveira",
                "org": "faculdade de ciencias e tecnologia da universidade nova de lisboa"
            }
        ],
        "venue": "MMAR",
        "year": 2015
    },
    "E4jYGhrg": {
        "id": "E4jYGhrg",
        "title": "Modelling of a post-combustion CO 2 capture process using extreme learning machine",
        "abstract": "This paper presents modelling of a post-combustion CO 2  capture process using bootstrap aggregated extreme learning machine. Extreme learning machine (ELM) randomly assigns the weights between input and hidden layers and obtains the weights between the hidden layer and output layer using regression type approach in one step. This paper proposes using principal component regression to obtain the weights between the hidden and output layers. Due to the weights between input and hidden layers are randomly assigned, ELM could have variations in performance. This paper proposes combining multiple ELMs to enhance model prediction accuracy and reliability. To predict the CO2 production rate and CO2 capture level, seven parameters in the process were regarded as input variables: inlet gas flow rate, CO2 concentration in inlet flow gas, inlet gas temperature, inlet gas pressure, lean solvent flowrate, lean solvent temperature, lean loading and reboiler duty. The bootstrap re-sampling of training data was applied for each single ELM and then the individual ELMs are stacked, thereby enhancing the model accuracy and reliability. The bootstrap aggregated extreme learning machine (BA-ELM) can provide fast learning speed and good generalization performance, which will be used to optimize the CO2 capture process.",
        "keywords": [
            "CO2 capture",
            " Neural networks",
            " Data-driven modelling",
            " Extreme learning machine"
        ],
        "authors": [
            {
                "name": "Fei Li",
                "org": "Newcastle University, Newcastle upon Tyne, NE1 7RU, UK"
            },
            {
                "name": "Jie Zhang",
                "org": "Newcastle University, Newcastle upon Tyne, NE1 7RU, UK"
            },
            {
                "name": "Eni Oko",
                "org": "Department of Chemical and Biological Engineering,University of Sheffield,Sheffield,UK"
            },
            {
                "name": "Meihong Wang",
                "org": "School of Engineering, University of Hull, Hull, HU6 7RX, UK"
            }
        ],
        "venue": "international conference on methods and models in automation and robotics",
        "year": 2016
    },
    "nrJsvCp9": {
        "id": "nrJsvCp9",
        "title": "Inferential disturbance observer based control of a binary distillation column.",
        "abstract": "This paper presents an integrated disturbance observer based control and inferential control of a binary distillation column. Disturbance observers have been shown being capable of providing excellent disturbance attenuation. Research into the application of inferential control methods in distillation columns have achieved a much higher quality of control in comparison to the feedback control using composition analyzers which possess substantial measurement delays. This paper takes the novel approach of integrating two frequency domain disturbance observers with multiple tray temperature based inferential estimations of top and bottom product compositions. In order to cope with colinearities in tray temperature measurements, principal component regression (PCR) and partial least square (PLS) regression are used in the soft sensor development. The number of principal components in the PCR model and the number of latent variables in the PLS model are determined using cross validation. The frequency domain disturbance observers have been designed by optimizing the value of the filter time constants within a first order filter, in order to maximize disturbance rejection. The proposed control approach is applied to a binary distillation column for separating methanol and water mixture.",
        "keywords": "",
        "authors": [
            {
                "name": "Simon William Jeffries",
                "org": "School of Chemical Engineering and Advanced Materials, Newcastle University, Newcastle upon Tyne NE1 7RU, UK"
            },
            {
                "name": "Shamsa Al-Abri",
                "org": "School of Chemical Engineering and Advanced Materials, Newcastle University, Newcastle upon Tyne NE1 7RU, UK"
            },
            {
                "name": "Jie Zhang",
                "org": "School of Chemical Engineering and Advanced Materials, Newcastle University, Newcastle upon Tyne NE1 7RU, UK"
            }
        ],
        "venue": "IECON",
        "year": 2016
    },
    "FJdJzwk6": {
        "id": "FJdJzwk6",
        "title": "Inferential active disturbance rejection control of a heat integrated distillation column.",
        "abstract": "Heat integrated distillation columns (HIDiC) can save around 50% of energy consumption compared to conventional distillation columns. To reach this amount of energy saving, the HIDiC should be properly controlled. The high thermally coupled nature of HIDiC leads to high loop interactions making HIDiC difficult to control. In order to improve control performance, inferential active disturbance rejection control (ADRC) for HIDiC is proposed in this paper. The proposed control scheme integrates ADRC strategy with inferential feedback control. Tray temperatures are used as secondary measurements to estimate the product compositions. Due to the strong collinearity in tray temperatures, principal component regression (PCR) is used to build the soft sensor from process operation data. The proposed technique is applied to a simulated HIDiC for separating Benzene-Toluene mixture. Simulation results demonstrate the effectiveness of the proposed approach.",
        "keywords": "",
        "authors": [
            {
                "name": "Fahad Khamis Al Kalbani",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": "School of Chemical Engineering and Advanced Materials, Newcastle University, Newcastle upon Tyne NE1 7RU, UK"
            }
        ],
        "venue": "ICARCV",
        "year": 2016
    },
    "z1jUTHiF": {
        "id": "z1jUTHiF",
        "title": "Energy efficiency optimisation for distillation column using artificial neural network models",
        "abstract": "This paper presents a neural network based strategy for the modelling and optimisation of energy efficiency in distillation columns incorporating the second law of thermodynamics. Real-time optimisation of distillation columns based on mechanistic models is often infeasible due to the effort in model development and the large computation effort associated with mechanistic model computation. This issue can be addressed by using neural network models which can be quickly developed from process operation data. The computation time in neural network model evaluation is very short making them ideal for real-time optimisation. Bootstrap aggregated neural networks are used in this study for enhanced model accuracy and reliability. Aspen HYSYS is used for the simulation of the distillation systems. Neural network models for exergy efficiency and product compositions are developed from simulated process operation data and are used to maximise exergy efficiency while satisfying products qualities constraints. Applications to binary systems of methanol-water and benzene-toluene separations culminate in a reduction of utility consumption of 8.2% and 28.2% respectively. Application to multi-component separation columns also demonstrate the effectiveness of the proposed method with a 32.4% improvement in the exergy efficiency.",
        "keywords": "",
        "authors": [
            {
                "name": "Funmilayo N. Osuolale",
                "org": "School of Chemical Engineering and Advanced Materials, Newcastle University, Newcastle upon Tyne NE1 7RU, UK"
            },
            {
                "name": "Jie Zhang",
                "org": "School of Chemical Engineering and Advanced Materials, Newcastle University, Newcastle upon Tyne NE1 7RU, UK"
            }
        ],
        "venue": "Energy",
        "year": 2016
    },
    "SVY6iEqh": {
        "id": "SVY6iEqh",
        "title": "Phase partition for nonlinear batch process monitoring",
        "abstract": "Abstract   A window-based step-wise sequential phase partition method is proposed for monitoring nonlinear batch processes with multiphase operations. The three-dimensional batch data are unfolded in the batch-wise direction to facilitate establishing the kernel principle component analysis (KPCA) models. A moving window is introduced to maintain the kernel parameters unchanged for computation while preserving the time sequence of different phases, thus capable of significantly reducing the storage space of kernel matrices and the computation complexity. A numerical case and a penicillin fermentation process are used to demonstrate the effectiveness and merit of the proposed method.",
        "keywords": "",
        "authors": [
            {
                "name": "Jingxiang Liu",
                "org": "Institute of Advanced Control Technology, Dalian University of Technology, Dalian, 116024, P. R. China"
            },
            {
                "name": "Tao Liu",
                "org": "Institute of Advanced Control Technology, Dalian University of Technology, Dalian, 116024, P. R. China"
            },
            {
                "name": "Jie Zhang",
                "org": "School of Chemical Engineering and Advanced Materials, Newcastle University, Newcastle upon Tyne NE1 7RU, UK"
            }
        ],
        "venue": "IFAC-PapersOnLine",
        "year": 2016
    },
    "49ZTKfZ4": {
        "id": "49ZTKfZ4",
        "title": "Improving water quality index prediction in Perak River Basin Malaysia through the combination of multiple neural networks",
        "abstract": "ABSTRACTThis paper proposes a method for the real-time prediction of water quality index (WQI) by excluding the biological oxygen demand and chemical oxygen demand, which are not measured in real time, from the model inputs. In this study, feedforward artificial neural networks are used to model the WQI in Perak River basin Malaysia due to its capability in modelling nonlinear systems. The results show that the developed single feedforward neural network model can predict WQI very well with the coefficient of determination R2 and mean squared error (MSE) of 0.9090 and 0.1740 on the unseen validation data, respectively. In addition to that, the aggregation of multiple neural networks in predicting the WQI further improves the prediction performance on the unseen validation data. Forward selection and backward elimination selective combination methods are used to combine multiple neural networks and both methods lead to 6 and 5 networks being combined with R2 and MSE of 0.9340, 0.9270 and 0.1156, 0.1256, re...",
        "keywords": "",
        "authors": [
            {
                "name": "Zainal Arifin Ahmad",
                "org": "School of Chemical Engineering, University Sains Malaysia, Nibong Tebal, Penang, Malaysia"
            },
            {
                "name": "N. A. Rahim",
                "org": "School of Chemical Engineering, University Sains Malaysia, Nibong Tebal, Penang, Malaysia"
            },
            {
                "name": "Alireza Bahadori",
                "org": "School of Environment, Science and Engineering, Southern Cross University, Lismore, NSW, Australia"
            },
            {
                "name": "Jie Zhang",
                "org": "School of Chemical Engineering and Advanced Materials, Newcastle University, Newcastle upon Tyne, UK"
            }
        ],
        "venue": "International Journal of River Basin Management",
        "year": 2017
    },
    "2TvCgb8E": {
        "id": "2TvCgb8E",
        "title": "Re-optimisation Control of a Fed-batch Fermentation Process using Bootstrap Aggregated Extreme Learning Machine.",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Carolina Maria Cardona Baron",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": "Newcastle University"
            }
        ],
        "venue": "ICINCO",
        "year": 2017
    },
    "gDWB8Wg4": {
        "id": "gDWB8Wg4",
        "title": "Actuator and Sensor Fault Tolerant Control of a Crude Distillation Unit",
        "abstract": "Abstract   This work presents preservation of the integrity of crude distillation unit, as the first major critical unit in a refinery operation, in the presence of actuator and sensor faults. This is achieved through the application of integrated fault-tolerant model predictive control and fault-tolerant inferential control to respectively accommodate actuator and sensor faults during operation, hence maintaining the integrity of the operation. An interactive dynamic system is developed by integrating an HYSYS crude distillation model with MATLAB to simulate the system for normal and various actuator and sensor faults. Operations of the crude distillation unit is monitored for actuator and sensor faults through MATLAB using the developed dynamic principal component analysis based diagnostics model with data collected during normal operation. When an actuator fault is diagnosed, fault-tolerant model predictive control is applied to restructure the remaining healthy actuators based on pre-assessed control structure reconfiguration. FTIC is applied to accommodate sensor faults when diagnosed using a dynamic partial least square based soft-sensor estimates of the measured controlled variable in place of the faulty sensor outputs. Application results on a simulated crude distillation unit attest to the efficacy of the proposed approaches.",
        "keywords": "",
        "authors": [
            {
                "name": "Sulaiman A. Lawal",
                "org": "School of Chemical Engineering and Advanced Materials, Newcastle University, Newcastle upon Tyne NE1 7RU, UK"
            },
            {
                "name": "Sulaiman A. Lawal",
                "org": "School of Chemical Engineering and Advanced Materials, Newcastle University, Newcastle upon Tyne NE1 7RU, UK"
            },
            {
                "name": "Jie Zhang",
                "org": "School of Chemical Engineering and Advanced Materials, Newcastle University, Newcastle upon Tyne NE1 7RU, UK"
            }
        ],
        "venue": "Computer-aided chemical engineering",
        "year": 2017
    },
    "RajcLn28": {
        "id": "RajcLn28",
        "title": "THE DEVELOPMENT OF THE HTS RF SQUID MAGNETOMETER AND ITS APPLICATION TO TEM",
        "abstract": "The HTS RF SQUID magnetometer is characterized by low noise,high sensitivity,and wide dynamic and frequency ranges.It can therefore be used to measure the magnetic field directly.Theoretically,the HTS RF SQUID magnetometer has superiority over the conventional inductive probe in TEM application.The tentative TEM survey for comparison was carried out in field by using HTS RF SQUID magnetometer and induction,and the results show that larger detection depth could be expected in TEM survey by using the HTS RF SQUID magnetometer.",
        "keywords": [
            "Radio frequency superconducting quantum interference device(RF SQUID)",
            "Transient Electromagnetic Method(TEM)",
            "magnetometer"
        ],
        "authors": [
            {
                "name": "CHEN Xiao-dong",
                "org": "China University of Geosciences,Beijing ,China;Institute of Geophysical and Geochemical Exploration,CAGS,Langfang ,China"
            },
            {
                "name": "ZHAO Yi",
                "org": "Institute of Geophysical and Geochemical Exploration,CAGS,Langfang ,China"
            },
            {
                "name": "DENG Xiao-hong",
                "org": "China University of Geosciences,Beijing ,China;Institute of Geophysical and Geochemical Exploration,CAGS,Langfang ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Institute of Geophysical and Geochemical Exploration,CAGS,Langfang ,China"
            },
            {
                "name": "Zhao Jing-xi",
                "org": "Institute of Geophysical and Geochemical Exploration,CAGS,Langfang ,China"
            }
        ],
        "venue": "Geophysical and Geochemical Exploration",
        "year": 2006
    },
    "RSpRJx89": {
        "id": "RSpRJx89",
        "title": "THE HIGH TEMPERATURE SUPERCONDUCTIVITY TEM TRANSIENT MAGNETIC FIELD PSEUDO-2D INVERSION AND ITS APPLICATION EFFECT",
        "abstract": "Theory and practice show that the observation of the transient magnetic field in the TEM has more advantages than that of the induced EMF.With the application and improvement of the high-temperature superconducting technology,the direct observation of transient magnetic field signal has become a reality in the TEM.However,the retrieve interpretation method for transient magnetic field data has become an urgent problem.In this paper,drawing on the interpretation method of the induced EMF,the authors made an overall explanation of the definition of apparent resistivity based on a study of the transient magnetic field and probed into the TEM transient magnetic field for PSEUDO-2D inverse technology.From the theoretical model and the measured data,the authors have verified the practicality of the method,which can provide technical support for the development of the high-temperature superconductor TEM method.",
        "keywords": [
            "transient magnetic field",
            "TEM",
            "PSEUDO-2D inversion",
            "high-temperature superconductor"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Institute of Geophysical and Geochemical Exploration,Langfang ,China"
            },
            {
                "name": "LV Guo-yin",
                "org": "Institute of Geophysical and Geochemical Exploration,Langfang ,China"
            },
            {
                "name": "GUO Bu-ling",
                "org": "Hebei Institute of Regional Geological Survey for Mineral Resources,Langfang ,China"
            },
            {
                "name": "CHEN Xiao-dong",
                "org": "Institute of Geophysical and Geochemical Exploration,Langfang ,China"
            },
            {
                "name": "WU Jun-jie",
                "org": "Institute of Geophysical and Geochemical Exploration,Langfang ,China"
            },
            {
                "name": "WANG Xing-chun",
                "org": "Institute of Geophysical and Geochemical Exploration,Langfang ,China"
            }
        ],
        "venue": "Geophysical and Geochemical Exploration",
        "year": 2010
    },
    "FN9r4VWa": {
        "id": "FN9r4VWa",
        "title": "THE EVALUATION OF TEM ANTI-INTERFERENCE MEASURES IN DATA ACQUISITION",
        "abstract": "Anti-interference measures must be adopted in coalfield where noise level is heavy to guarantee the quality of data collected.The evaluation of parameters is necessary for understanding the effectiveness of the measures.TEM S/N and its calculation method are given in this paper to evaluate the effectiveness of the anti-interference measures.The TEM S/N data were statistically analyzed by using field data processed with different measures,and the result shows that the S/N parameter can display the effectiveness reasonably and the calculation is easy.",
        "keywords": [
            "TEM",
            "S/N",
            "anti-interference",
            "coalfield exploration",
            "evaluation",
            "noise"
        ],
        "authors": [
            {
                "name": "WU Jun-Jie",
                "org": "Institute of Geophysical and Geochemical Exploration,CAGS,Langfang ,China"
            },
            {
                "name": "WANG Xing-Chun",
                "org": "Institute of Geophysical and Geochemical Exploration,CAGS,Langfang ,China"
            },
            {
                "name": "DENG Xiao-Hong",
                "org": "Institute of Geophysical and Geochemical Exploration,CAGS,Langfang ,China"
            },
            {
                "name": "LV Guo-Yin",
                "org": "Institute of Geophysical and Geochemical Exploration,CAGS,Langfang ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Institute of Geophysical and Geochemical Exploration,CAGS,Langfang ,China"
            },
            {
                "name": "YANG Yi",
                "org": "Institute of Geophysical and Geochemical Exploration,CAGS,Langfang ,China"
            }
        ],
        "venue": "Geophysical and Geochemical Exploration",
        "year": 2012
    },
    "AtbRf04g": {
        "id": "AtbRf04g",
        "title": "FEASIBILITY ANALYSIS OF THE 1D INVERSION WITH INCOMPLETE TEM DATA",
        "abstract": "The three layer model forward data and observed TEM data was calculated to test the effect of the inversion with incomplete TEM data,and it was tried how to make full use of incomplete data.The results show that the inversion with incomplete data can help to obtain additional information about the geological target,and this approach can be a remedy of the exploration especially in noisy area.It is on the base that the TEM decay curve is normal the inversion can be carry out,but it is not reasonable when decay curve is abnormal.",
        "keywords": [
            "inversion",
            "TEM",
            "feasibility",
            "incomplete data"
        ],
        "authors": [
            {
                "name": "WU Jun-jie",
                "org": "Institute of Geophysical and Geochemical Exploration CAGS,Langfang ,China"
            },
            {
                "name": "DENG Xiao-hong",
                "org": "Institute of Geophysical and Geochemical Exploration CAGS,Langfang ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Institute of Geophysical and Geochemical Exploration CAGS,Langfang ,China"
            }
        ],
        "venue": "Computing Techniques for Geophysical and Geochemical Exploration",
        "year": 2012
    },
    "e5l4sFB2": {
        "id": "e5l4sFB2",
        "title": "A COMPARISON AND ANALYSIS OF THREE SETS OF TEM SOFTWARE ABROAD",
        "abstract": "On the basis of a study and analysis of three sets of dominant transient electromagnetic software abroad(Maxwell,EM vision and Emigma),the authors designed tabular or prismatic bodies with homogeneous half-space,layered earth and homogeneous half-space and compares the difference between them.1D inversion was carried out with homogeneous half-space and layered earth too.The forward and inversion results have led the authors to reach the conclusion that in some circumstances these sets of software can yield the same results,but there still exist some differences under different conditions.",
        "keywords": [
            "transient electromagnetic forward and inversion calculation",
            "Maxwell",
            "transient electromagnetic software",
            "Emigma",
            "EM vision"
        ],
        "authors": [
            {
                "name": "WANG Xing-chun",
                "org": "Institute of Geophysical and Geochemical Exploration,CAGS,Langfang ,China"
            },
            {
                "name": "WU Jun-jie",
                "org": "Institute of Geophysical and Geochemical Exploration,CAGS,Langfang ,China"
            },
            {
                "name": "DENG Xiao-hong",
                "org": "Institute of Geophysical and Geochemical Exploration,CAGS,Langfang ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Institute of Geophysical and Geochemical Exploration,CAGS,Langfang ,China"
            },
            {
                "name": "YANG Yi",
                "org": "Institute of Geophysical and Geochemical Exploration,CAGS,Langfang ,China"
            }
        ],
        "venue": "Geophysical and Geochemical Exploration",
        "year": 2012
    },
    "cLOPB7pn": {
        "id": "cLOPB7pn",
        "title": "THE METHOD FOR CALCULATING x-COMPONENT APPARENT RESISTIVITY OF TEM FIXED-LOOP",
        "abstract": "For the purpose of obtaining the x-component apparent resistivity of fixed-loop TEM,the authors made the fixed-loop equivalent to some vertical magnetic dipoles so as to calculate the x-component TEM response.The x-component apparent resistivity of fixed-loop TEM can be obtained when channel data of every time are fitted by response of uniform halfspace,and each halfspace resistivity can be regarded as corresponding channel′s apparent resistivity.The calculation results indicate that the method is effective and its precision is enough,and hence this tecnique can provide necessary basis for the comprehensive interpretation of two or three components with the fixed loop TEM method.",
        "keywords": [
            "TEM",
            "apparent resistivity",
            "fixed-loop",
            "x-component"
        ],
        "authors": [
            {
                "name": "WU Jun-jie",
                "org": "Institute of Geophysical and Geochemical Exploration,CAGS,Langfang ,China"
            },
            {
                "name": "WANG Xing-chun",
                "org": "Institute of Geophysical and Geochemical Exploration,CAGS,Langfang ,China"
            },
            {
                "name": "DENG Xiao-hong",
                "org": "Institute of Geophysical and Geochemical Exploration,CAGS,Langfang ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Institute of Geophysical and Geochemical Exploration,CAGS,Langfang ,China"
            },
            {
                "name": "YANG Yi",
                "org": "Institute of Geophysical and Geochemical Exploration,CAGS,Langfang ,China"
            }
        ],
        "venue": "Geophysical and Geochemical Exploration",
        "year": 2012
    },
    "qqV7FCe8": {
        "id": "qqV7FCe8",
        "title": "TWO STUDY CASES ON TRANSIENT ELECTROMAGNETIC METHOD",
        "abstract": "Aiming at two problems appeared in transient electromagnetic method of fixed loop data inverted by in-loop way and the low-resistivity shielding effect in down hole TEM prospecting,we make some forward and inversion models for the first case and make four forward models for the second case by using Maxwell software.The results indicate that there is a risk for the first problem especially under low resistivity of the layer and distance between central point and station.The later forward results tell us that when there is a low resistivity layer underground we can increase the transmitted magnetic moment and measure magnetic can collect the target singles beneath the low resistivity layer,and the results also illustrate that X component is more sensitivity to conductor than Z component in downhole TEM prospecting.",
        "keywords": [
            "in-loop",
            "down hole TEM",
            "fixed-loop",
            "Maxwell software",
            "low-resistivity shielding effect"
        ],
        "authors": [
            {
                "name": "WANG Xing-chun",
                "org": "Institute of Geophysical and Geochemical Exploration,CAGS.Langfang ,China"
            },
            {
                "name": "DENG Xiao-hong",
                "org": "Institute of Geophysical and Geochemical Exploration,CAGS.Langfang ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Institute of Geophysical and Geochemical Exploration,CAGS.Langfang ,China"
            }
        ],
        "venue": "Computing Techniques for Geophysical and Geochemical Exploration",
        "year": 2013
    },
    "zHpZ9dqD": {
        "id": "zHpZ9dqD",
        "title": "The anti-interference measures with electromagnetic method in noisy area strong level and the analysis of effect",
        "abstract": "Electromagnetic method exploration faces strong and extensive electromagnetic interference. The anti-interference measures of different method and effect is introduced in this paper based on a large number of field test. The field test result show that it is suitable for TEM method to take the data collection method of high-power, multiple stack number, multiple repeated observation and noise monitoring. It is reasonable for CSAMT method to take large current, multiple notch filter, multiple repeated observation and noise monitoring data collection method. The multiple notch filter is suggested in AMT exploration, but AMT method is not suggested in strong noisy level area.",
        "keywords": [
            "Anti-interference method",
            "Electromagnetic method",
            "Strong noisy level area"
        ],
        "authors": [
            {
                "name": "WU Jun-jie",
                "org": "Institute of Geophysical and Geochemical Exploration Langfang(Institute of Geophysical and Geochemical Exploration,Inst of Geophysical and Geochemical),Langfang,China"
            },
            {
                "name": "DENG Xiao-hong",
                "org": "Institute of Geophysical and Geochemical Exploration Langfang(Institute of Geophysical and Geochemical Exploration,Inst of Geophysical and Geochemical),Langfang,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Institute of Geophysical and Geochemical Exploration Langfang(Institute of Geophysical and Geochemical Exploration,Inst of Geophysical and Geochemical),Langfang,China"
            }
        ],
        "venue": "Computing Techniques for Geophysical and Geochemical Exploration",
        "year": 2013
    },
    "ObtiiKT2": {
        "id": "ObtiiKT2",
        "title": "Terahertz radiation by two-color lasers due to the field ionization of gases",
        "abstract": "Terahertz (THz) radiation via the two-color laser scheme is investigated theoretically and numerically when the second laser is at different harmonic orders of the main laser. It is found that THz radiation can be generated only when the second laser is an even harmonic and the THz field strength does not show a simple scaling with the two laser amplitudes, suggesting that this is different from normal optical rectification or frequency mixing processes. The THz strength generally tends to decrease with increase of the even harmonic order. The strength is also sensitive to the carrier envelope (CE) phases of both the laser pulses even if their durations are quite long. With different CE phases, the strength can be proportional to either the sine or cosine of the relative phase displacement of the two lasers. For a given gas target except hydrogen, it increases with the laser amplitude between several saturation plateaus, each corresponding to a different ionization level. For a given main laser intensity, there is an optimized intensity of the second laser for the strongest THz radiation. © 2013 American Physical Society.",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Weimin Wang",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Yutong Li",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Zhengming Sheng",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Xin Lu",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            }
        ],
        "venue": "Physical Review E - Statistical, Nonlinear, and Soft Matter Physics",
        "year": 2013
    },
    "JRdX8rs0": {
        "id": "JRdX8rs0",
        "title": "Particle simulation of mode transition in dielectric barrier discharges at different gas pressures",
        "abstract": "The dielectric barrier discharges (DBDs) at different gas pressures are investigated by use of two-dimensional particle-in-cell simulation with Monte Carlo collisions included. The pressure-dependent transition from Townsend to filamentary discharge operating in a glow regime has been demonstrated. In the filamentary discharge, four different phases are distinguished: a Townsend phase, a space-charge dominated avalanche phase, a cathode-layer formation, and a decay phase. The evolution of the electric fields, plasma densities, kinetic energy distributions, filament diameters, and breakdown voltages associated with different discharges has been presented. The above simulation results are in good agreement with previous experimental observations, suggesting that such simulation may provide guidance for the control of DBDs. © 2013 IOP Publishing Ltd.",
        "keywords": [],
        "authors": [
            {
                "name": "Weili Fan",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Zhengming Sheng",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "WeiMin Wang",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Yunqian Cui",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Xiaoxia Zhong",
                "org": "Shanghai Jiaotong University(Shanghai Jiaotong University,Shanghai Jiao Tong University,Shanghai Jiaotong Univ.),Shanghai,China"
            },
            {
                "name": "Yutong Li",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Institute of Physics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            }
        ],
        "venue": "Journal of Physics D: Applied Physics",
        "year": 2013
    },
    "eCP5BKFq": {
        "id": "eCP5BKFq",
        "title": "Particle-in-cell simulations of magnetic reconnection in laser-plasma experiments on Shenguang-II facility",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "san lu",
                "org": ""
            },
            {
                "name": "quanming lu",
                "org": ""
            },
            {
                "name": "quanli dong",
                "org": ""
            },
            {
                "name": "can huang",
                "org": ""
            },
            {
                "name": "shui wang",
                "org": ""
            },
            {
                "name": "jianqiang zhu",
                "org": ""
            },
            {
                "name": "zhengming sheng",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            }
        ],
        "venue": "Physics of Plasmas",
        "year": 2013
    },
    "pYEPHIEB": {
        "id": "pYEPHIEB",
        "title": "Robust relativistic electron mirrors in laser wakefields for enhanced Thomson backscattering",
        "abstract": "",
        "keywords": [
            "physics"
        ],
        "authors": [
            {
                "name": "j mu",
                "org": ""
            },
            {
                "name": "f y li",
                "org": ""
            },
            {
                "name": "ming zeng",
                "org": ""
            },
            {
                "name": "min chen",
                "org": ""
            },
            {
                "name": "zhengming sheng",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            }
        ],
        "venue": "Applied Physics Letters",
        "year": 2013
    },
    "0RCCgchY": {
        "id": "0RCCgchY",
        "title": "Particle-in-Cell Simulations of Fast Magnetic Reconnection in Laser-Plasma Interaction",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "shui wang",
                "org": ""
            },
            {
                "name": "zhengming sheng",
                "org": ""
            },
            {
                "name": "mingyu wu",
                "org": ""
            },
            {
                "name": "can huang",
                "org": ""
            },
            {
                "name": "san lu",
                "org": ""
            },
            {
                "name": "quanli dong",
                "org": ""
            },
            {
                "name": "quanming lu",
                "org": ""
            },
            {
                "name": "zechen zhang",
                "org": ""
            }
        ],
        "venue": "Chinese Physics Letters",
        "year": 2013
    },
    "2j8r0pSv": {
        "id": "2j8r0pSv",
        "title": "Spectral characteristics of terahertz radiation from splitting femtosecond laser filaments",
        "abstract": "We experimentally observe two independent terahertz sources with different peak frequencies emitted from a femtosecond laser pulse induced air filament when the filament splits into two sub-filaments. The frequency of terahertz waves from the trailing sub-filament is higher than that from the leading sub-filament.",
        "keywords": [
            "lasers",
            "light sources",
            "terahertz waves",
            "femtosecond laser filament splitting",
            "femtosecond laser pulse induced air filament",
            "independent terahertz sources",
            "spectral characteristics",
            "terahertz radiation",
            "terahertz wave frequency"
        ],
        "authors": [
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "liu yang",
                "org": ""
            },
            {
                "name": "xiaohui yuan",
                "org": ""
            },
            {
                "name": "feng liu",
                "org": ""
            },
            {
                "name": "min chen",
                "org": ""
            },
            {
                "name": "jianqiu xu",
                "org": ""
            },
            {
                "name": "zhengming sheng",
                "org": ""
            },
            {
                "name": "zhelin zhang",
                "org": ""
            },
            {
                "name": "yanping chen",
                "org": ""
            }
        ],
        "venue": "Infrared, Millimeter, and Terahertz waves",
        "year": 2014
    },
    "CXa053Bj": {
        "id": "CXa053Bj",
        "title": "Three-dimensional fast magnetic reconnection driven by relativistic ultraintense femtosecond lasers.",
        "abstract": "Three-dimensional fast magnetic reconnection driven by two ultraintense femtosecond laser pulses is investigated by relativistic particle-in-cell simulation, where the two paralleled incident laser beams are shot into a near-critical plasma layer to form a magnetic reconnection configuration in self-generated magnetic fields. A reconnection X point and out-of-plane quadrupole field structures associated with magnetic reconnection are formed. The reconnection rate is found to be faster than that found in previous two-dimensional Hall magnetohydrodynamic simulations and electrostatic turbulence contribution to the reconnection electric field plays an essential role. Both in-plane and out-of-plane electron and ion accelerations up to a few MeV due to the magnetic reconnection process are also obtained.",
        "keywords": [],
        "authors": [
            {
                "name": "Y L Ping",
                "org": "Key Laboratory of Optical Astronomy, National Astronomical Observatories, Chinese Academy of Sciences, Beijing 100012, China."
            },
            {
                "name": "J Y Zhong",
                "org": "Key Laboratory of Optical Astronomy, National Astronomical Observatories, Chinese Academy of Sciences, Beijing 100012, China."
            },
            {
                "name": "Z M Sheng",
                "org": "Key Laboratory for Laser Plasmas (MOE) and Department of Physics and Astronomy, Shanghai Jiao Tong University, Shanghai 200240, China and Beijing National Laboratory of Condensed Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing 100080, China."
            },
            {
                "name": "X G Wang",
                "org": "State Key Laboratory of Nuclear Physics and Technology, School of Physics, Peking University, Beijing 100871, China."
            },
            {
                "name": "B Liu",
                "org": "Center for Applied Physics and Technology, Peking University, Beijing 100084, China."
            },
            {
                "name": "Y T Li",
                "org": "Beijing National Laboratory of Condensed Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing 100080, China."
            },
            {
                "name": "X Q Yan",
                "org": "State Key Laboratory of Nuclear Physics and Technology, School of Physics, Peking University, Beijing 100871, China and Center for Applied Physics and Technology, Peking University, Beijing 100084, China."
            },
            {
                "name": "X T He",
                "org": "Center for Applied Physics and Technology, Peking University, Beijing 100084, China."
            },
            {
                "name": "J Zhang",
                "org": "Key Laboratory for Laser Plasmas (MOE) and Department of Physics and Astronomy, Shanghai Jiao Tong University, Shanghai 200240, China and Beijing National Laboratory of Condensed Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing 100080, China."
            },
            {
                "name": "G Zhao",
                "org": "Key Laboratory of Optical Astronomy, National Astronomical Observatories, Chinese Academy of Sciences, Beijing 100012, China."
            }
        ],
        "venue": "Physical review. E, Statistical, nonlinear, and soft matter physics",
        "year": 2014
    },
    "g1lBbOAA": {
        "id": "g1lBbOAA",
        "title": "Investigation of transient surface electric field induced by femtosecond laser irradiation of aluminum",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "runze li",
                "org": "shanghai jiao tong university"
            },
            {
                "name": "pengfei zhu",
                "org": "shanghai jiao tong university"
            },
            {
                "name": "long chen",
                "org": "shanghai jiao tong university"
            },
            {
                "name": "tong xu",
                "org": "shanghai jiao tong university"
            },
            {
                "name": "jie chen",
                "org": "shanghai jiao tong university"
            },
            {
                "name": "jianming cao",
                "org": "shanghai jiao tong university"
            },
            {
                "name": "zhengming sheng",
                "org": "shanghai jiao tong university"
            },
            {
                "name": "jie zhang",
                "org": "shanghai jiao tong university"
            }
        ],
        "venue": "New Journal of Physics",
        "year": 2014
    },
    "3740ktjk": {
        "id": "3740ktjk",
        "title": "Coherent keV backscattering from plasma-wave boosted relativistic electron mirrors",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "f y li",
                "org": ""
            },
            {
                "name": "z m sheng",
                "org": ""
            },
            {
                "name": "man chen",
                "org": ""
            },
            {
                "name": "h c wu",
                "org": ""
            },
            {
                "name": "yunfeng liu",
                "org": ""
            },
            {
                "name": "j meyertervehn",
                "org": ""
            },
            {
                "name": "warren b mori",
                "org": ""
            },
            {
                "name": "jinping zhang",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2014
    },
    "L7LKaxic": {
        "id": "L7LKaxic",
        "title": "Coherent kilo-electron-volt backscattering from plasma-wave boosted relativistic electron mirrors",
        "abstract": "",
        "keywords": [
            "physics"
        ],
        "authors": [
            {
                "name": "f y li",
                "org": ""
            },
            {
                "name": "z m sheng",
                "org": ""
            },
            {
                "name": "min chen",
                "org": ""
            },
            {
                "name": "h c wu",
                "org": ""
            },
            {
                "name": "y liu",
                "org": ""
            },
            {
                "name": "j meyertervehn",
                "org": "max planck institute of quantum optics"
            },
            {
                "name": "warren b mori",
                "org": ""
            },
            {
                "name": "j zhang",
                "org": ""
            }
        ],
        "venue": "Applied Physics Letters",
        "year": 2014
    },
    "VTKj6W07": {
        "id": "VTKj6W07",
        "title": "Concurrence of monoenergetic electron beams and bright X-rays from an evolving laser-plasma bubble.",
        "abstract": "Desktop laser plasma acceleration has proven to be able to generate gigaelectronvolt-level quasi-monoenergetic electron beams. Moreover, such electron beams can oscillate transversely (wiggling motion) in the laser-produced plasma bubble/channel and emit collimated ultrashort X-ray flashes known as betatron radiation with photon energy ranging from kiloelectronvolts to megaelectronvolts. This implies that usually one cannot obtain bright betatron X-rays and high-quality electron beams with low emittance and small energy spread simultaneously in the same accelerating wave bucket. Here, we report the first (to our knowledge) experimental observation of two distinct electron bunches in a single laser shot, one featured with quasi-monoenergetic spectrum and another with continuous spectrum along with large emittance. The latter is able to generate high-flux betatron X-rays. Such is observed only when the laser self-guiding is extended over 4 mm at a fixed plasma density (4 × 10(18) cm(-3)). Numerical simulation reveals that two bunches of electrons are injected at different stages due to the bubble evolution. The first bunch is injected at the beginning to form a stable quasi-monoenergetic electron beam, whereas the second one is injected later due to the oscillation of the bubble size as a result of the change of the laser spot size during the propagation. Due to the inherent temporal synchronization, this unique electron-photon source can be ideal for pump-probe applications with femtosecond time resolution.",
        "keywords": [
            "biomedical research",
            "bioinformatics",
            "physics"
        ],
        "authors": [
            {
                "name": "Wenchao Yan",
                "org": "Beijing National Laboratory for Condensed Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing 100190, China;"
            },
            {
                "name": "Liming Chen",
                "org": "Beijing National Laboratory for Condensed Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing 100190, China;"
            },
            {
                "name": "Dazhang Li",
                "org": "Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, China;"
            },
            {
                "name": "Lu Zhang",
                "org": "Beijing National Laboratory for Condensed Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing 100190, China;"
            },
            {
                "name": "Nasr A M Hafz",
                "org": "Key Laboratory for Laser Plasmas (Ministry of Education), Department of Physics and Astronomy, Shanghai Jiao Tong University, Shanghai 200240, China;"
            },
            {
                "name": "James Dunn",
                "org": "Lawrence Livermore National Laboratory, CA 94550"
            },
            {
                "name": "Yong Ma",
                "org": "Beijing National Laboratory for Condensed Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing 100190, China;"
            },
            {
                "name": "Kai Huang",
                "org": "Beijing National Laboratory for Condensed Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing 100190, China;"
            },
            {
                "name": "Luning Su",
                "org": "Beijing National Laboratory for Condensed Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing 100190, China;"
            },
            {
                "name": "Min Chen",
                "org": "Key Laboratory for Laser Plasmas (Ministry of Education), Department of Physics and Astronomy, Shanghai Jiao Tong University, Shanghai 200240, China;"
            },
            {
                "name": "Zhengming Sheng",
                "org": "Key Laboratory for Laser Plasmas (Ministry of Education), Department of Physics and Astronomy, Shanghai Jiao Tong University, Shanghai 200240, China;;Scottish Universities Physics Alliance, Department of Physics, University of Strathclyde, Glasgow G4 0NG, United Kingdom"
            },
            {
                "name": "Jie Zhang",
                "org": "Key Laboratory for Laser Plasmas (Ministry of Education), Department of Physics and Astronomy, Shanghai Jiao Tong University, Shanghai 200240, China;"
            }
        ],
        "venue": "Proceedings of the National Academy of Sciences of the United States of America",
        "year": 2014
    },
    "AZobLwsw": {
        "id": "AZobLwsw",
        "title": "Dual-frequency terahertz emission from splitting filaments induced by lens tilting in air",
        "abstract": "",
        "keywords": [
            "physics"
        ],
        "authors": [
            {
                "name": "zhelin zhang",
                "org": ""
            },
            {
                "name": "yanping chen",
                "org": ""
            },
            {
                "name": "liu yang",
                "org": ""
            },
            {
                "name": "xiaohui yuan",
                "org": ""
            },
            {
                "name": "feng liu",
                "org": ""
            },
            {
                "name": "min chen",
                "org": ""
            },
            {
                "name": "jianqiu xu",
                "org": ""
            },
            {
                "name": "zhengming sheng",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            }
        ],
        "venue": "Applied Physics Letters",
        "year": 2014
    },
    "4PPlUiYq": {
        "id": "4PPlUiYq",
        "title": "Control of THz wave emission by tuning relative phases between two color lasers",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "yanping chen",
                "org": "shanghai jiao tong university"
            },
            {
                "name": "zhen zhang",
                "org": "shanghai jiao tong university"
            },
            {
                "name": "xiaohui yuan",
                "org": "shanghai jiao tong university"
            },
            {
                "name": "min chen",
                "org": "shanghai jiao tong university"
            },
            {
                "name": "zhengming sheng",
                "org": "shanghai jiao tong university"
            },
            {
                "name": "jie zhang",
                "org": "shanghai jiao tong university"
            }
        ],
        "venue": "",
        "year": 2015
    },
    "YDJduFD6": {
        "id": "YDJduFD6",
        "title": "Absorption of ultrashort intense lasers in laser–solid interactions",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "min chen",
                "org": ""
            },
            {
                "name": "yunqian cui",
                "org": ""
            },
            {
                "name": "weimin wang",
                "org": ""
            },
            {
                "name": "lule yu",
                "org": ""
            },
            {
                "name": "suming weng",
                "org": ""
            },
            {
                "name": "zhengming sheng",
                "org": ""
            }
        ],
        "venue": "Chinese Physics B",
        "year": 2015
    },
    "Hxhe9lQP": {
        "id": "Hxhe9lQP",
        "title": "Mapping transient electric fields with picosecond electron bunches",
        "abstract": "Transient electric fields, which are an important but hardly explored parameter of laser plasmas, can now be diagnosed experimentally with combined ultrafast temporal resolution and field sensitivity, using femtosecond to picosecond electron or proton pulses as probes. However, poor spatial resolution poses great challenges to simultaneously recording both the global and local field features. Here, we present a direct 3D measurement of a transient electric field by time-resolved electron schlieren radiography with simultaneous 80-μm spatial and 3.7-ps temporal resolutions, analyzed using an Abel inversion algorithm. The electric field here is built up at the front of an aluminum foil irradiated with a femtosecond laser pulse at 1.9 × 1012 W/cm2, where electrons are emitted at a speed of 4 × 106 m/s, resulting in a unique “peak–valley” transient electric field map with the field strength up to 105 V/m. Furthermore, time-resolved schlieren radiography with charged particle pulses should enable the mapping of various fast-evolving field structures including those found in plasma-based particle accelerators.",
        "keywords": [],
        "authors": [
            {
                "name": "Long Chen",
                "org": "Key Laboratory for Laser Plasmas (Ministry of Education) and Department of Physics and Astronomy, Shanghai Jiao Tong University, Shanghai 200240, China;;Collaborative Innovation Center of Inertial Fusion Sciences and Applications (CICIFSA), Shanghai Jiao Tong University, Shanghai 200240, China;"
            },
            {
                "name": "Runze Li",
                "org": "Key Laboratory for Laser Plasmas (Ministry of Education) and Department of Physics and Astronomy, Shanghai Jiao Tong University, Shanghai 200240, China;;Collaborative Innovation Center of Inertial Fusion Sciences and Applications (CICIFSA), Shanghai Jiao Tong University, Shanghai 200240, China;"
            },
            {
                "name": "Jie Chen",
                "org": "Key Laboratory for Laser Plasmas (Ministry of Education) and Department of Physics and Astronomy, Shanghai Jiao Tong University, Shanghai 200240, China;;Collaborative Innovation Center of Inertial Fusion Sciences and Applications (CICIFSA), Shanghai Jiao Tong University, Shanghai 200240, China;"
            },
            {
                "name": "Pengfei Zhu",
                "org": "Key Laboratory for Laser Plasmas (Ministry of Education) and Department of Physics and Astronomy, Shanghai Jiao Tong University, Shanghai 200240, China;;Collaborative Innovation Center of Inertial Fusion Sciences and Applications (CICIFSA), Shanghai Jiao Tong University, Shanghai 200240, China;"
            },
            {
                "name": "Feng Liu",
                "org": "Key Laboratory for Laser Plasmas (Ministry of Education) and Department of Physics and Astronomy, Shanghai Jiao Tong University, Shanghai 200240, China;;Collaborative Innovation Center of Inertial Fusion Sciences and Applications (CICIFSA), Shanghai Jiao Tong University, Shanghai 200240, China;"
            },
            {
                "name": "Jianming Cao",
                "org": "Key Laboratory for Laser Plasmas (Ministry of Education) and Department of Physics and Astronomy, Shanghai Jiao Tong University, Shanghai 200240, China;;Physics Department and National High Magnetic Field Laboratory, Florida State University, Tallahassee, FL 32310;"
            },
            {
                "name": "Zhengming Sheng",
                "org": "Key Laboratory for Laser Plasmas (Ministry of Education) and Department of Physics and Astronomy, Shanghai Jiao Tong University, Shanghai 200240, China;;Collaborative Innovation Center of Inertial Fusion Sciences and Applications (CICIFSA), Shanghai Jiao Tong University, Shanghai 200240, China;;The Scottish Universities Physics Alliance, Department of Physics, University of Strathclyde, Glasgow G4 0NG, United Kingdom"
            },
            {
                "name": "Jie Zhang",
                "org": "Key Laboratory for Laser Plasmas (Ministry of Education) and Department of Physics and Astronomy, Shanghai Jiao Tong University, Shanghai 200240, China;;Collaborative Innovation Center of Inertial Fusion Sciences and Applications (CICIFSA), Shanghai Jiao Tong University, Shanghai 200240, China;"
            }
        ],
        "venue": "Proceedings of the National Academy of Sciences of the United States of America",
        "year": 2015
    },
    "I7WZFHrC": {
        "id": "I7WZFHrC",
        "title": "Erratum: Erratum: Generation of femtosecond γ-ray bursts stimulated by laser-driven hosing evolution",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Yong Ma",
                "org": ""
            },
            {
                "name": "Liming Chen",
                "org": ""
            },
            {
                "name": "Dazhang Li",
                "org": ""
            },
            {
                "name": "Wenchao Yan",
                "org": ""
            },
            {
                "name": "Kai Huang",
                "org": ""
            },
            {
                "name": "Min Chen",
                "org": ""
            },
            {
                "name": "Zhengming Sheng",
                "org": ""
            },
            {
                "name": "Kazuhisa Nakajima",
                "org": ""
            },
            {
                "name": "Toshiki Tajima",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            }
        ],
        "venue": "Scientific Reports",
        "year": 2016
    },
    "IpTUx2X1": {
        "id": "IpTUx2X1",
        "title": "Controllable Terahertz Radiation from a Linear-Dipole Array Formed by a Two-Color Laser Filament in Air.",
        "abstract": "We demonstrate effective control on the carrier-envelope phase and angular distribution as well as the peak intensity of a nearly single-cycle terahertz pulse emitted from a laser filament formed by two-color, the fundamental and the corresponding second harmonics, femtosecond laser pulses propagating in air. Experimentally, such control has been performed by varying the filament length and the initial phase difference between the two-color laser components. A linear-dipole-array model, including the descriptions of both the generation (via laser field ionization) and propagation of the emitted terahertz pulse, is proposed to present a quantitative interpretation of the observations. Our results contribute to the understanding of terahertz generation in a femtosecond laser filament and suggest a practical way to control the electric field of a terahertz pulse for potential applications.",
        "keywords": "",
        "authors": [
            {
                "name": "Zhelin Zhang",
                "org": "Collaborative Innovation Center of IFSA, Shanghai Jiao Tong University, Shanghai 200240, China."
            },
            {
                "name": "Yanping Chen",
                "org": "Collaborative Innovation Center of IFSA, Shanghai Jiao Tong University, Shanghai 200240, China."
            },
            {
                "name": "Min Chen",
                "org": "Collaborative Innovation Center of IFSA, Shanghai Jiao Tong University, Shanghai 200240, China."
            },
            {
                "name": "Zhen Zhang",
                "org": "Collaborative Innovation Center of IFSA, Shanghai Jiao Tong University, Shanghai 200240, China."
            },
            {
                "name": "Jin Yu",
                "org": "Key Laboratory for Laser Plasmas (Ministry of Education),Department of Physics and Astronomy, Shanghai Jiao Tong University, Shanghai 200240, China."
            },
            {
                "name": "Zhengming Sheng",
                "org": "Department of Physics, SUPA, University of Strathclyde, Glasgow G4 0NG, United Kingdom."
            },
            {
                "name": "Jie Zhang",
                "org": "Collaborative Innovation Center of IFSA, Shanghai Jiao Tong University, Shanghai 200240, China."
            }
        ],
        "venue": "Physical review letters",
        "year": 2016
    },
    "TQA29nrl": {
        "id": "TQA29nrl",
        "title": "Tunable synchrotron-like radiation from centimeter scale plasma channels",
        "abstract": "Synchrotron radiation (SR) sources are immensely useful tools for scientific researches and many practical applications. Currently, the state-of-the-art synchrotrons rely on conventional accelerators, where electrons are accelerated in a straight line and radiate in bending magnets or other insertion devices. However, these facilities are usually large and costly. Here, we study a compact all optical synchrotron-like radiation source based on laser-plasma acceleration either in a straight or a curved plasma channel. With the laser pulse off-axially injected, its centroid oscillates transversely in the plasma channel. This results in a wiggler motion of the whole accelerating structure and the self-trapped electrons behind the laser pulse, leading to strong synchrotron-like radiations with tunable spectra. It is further shown that a palmtop ring-shaped synchrotron is possible with current high power laser technologies. With its potential of high flexibility and tunability, such light sources once realized would find applications in wide areas and make up the shortage of large SR facilities.",
        "keywords": [
            "laser guiding",
            "laser wakefield acceleration",
            "synchrotron radiation"
        ],
        "authors": [
            {
                "name": "Min Chen",
                "org": "1Key Laboratory for Laser Plasmas (MOE), Department of Physics and Astronomy, Shanghai Jiao Tong University, Shanghai 200240, China;2Collaborative Innovation Center of IFSA (CICIFSA), Shanghai Jiao Tong University, Shanghai 200240, China"
            },
            {
                "name": "Ji Luo",
                "org": "1Key Laboratory for Laser Plasmas (MOE), Department of Physics and Astronomy, Shanghai Jiao Tong University, Shanghai 200240, China;2Collaborative Innovation Center of IFSA (CICIFSA), Shanghai Jiao Tong University, Shanghai 200240, China"
            },
            {
                "name": "Fei-Yu Li",
                "org": "3SUPA, Department of Physics, University of Strathclyde, Glasgow G4 0NG, UK"
            },
            {
                "name": "Feng Liu",
                "org": "1Key Laboratory for Laser Plasmas (MOE), Department of Physics and Astronomy, Shanghai Jiao Tong University, Shanghai 200240, China;2Collaborative Innovation Center of IFSA (CICIFSA), Shanghai Jiao Tong University, Shanghai 200240, China"
            },
            {
                "name": "Zheng-Ming Sheng",
                "org": "1Key Laboratory for Laser Plasmas (MOE), Department of Physics and Astronomy, Shanghai Jiao Tong University, Shanghai 200240, China;2Collaborative Innovation Center of IFSA (CICIFSA), Shanghai Jiao Tong University, Shanghai 200240, China;3SUPA, Department of Physics, University of Strathclyde, Glasgow G4 0NG, UK"
            },
            {
                "name": "Jie Zhang",
                "org": "1Key Laboratory for Laser Plasmas (MOE), Department of Physics and Astronomy, Shanghai Jiao Tong University, Shanghai 200240, China;2Collaborative Innovation Center of IFSA (CICIFSA), Shanghai Jiao Tong University, Shanghai 200240, China"
            }
        ],
        "venue": "Light: Science & Applications",
        "year": 2016
    },
    "8RYUIPwZ": {
        "id": "8RYUIPwZ",
        "title": "A compact tunable polarized X-ray source based on laser-plasma helical undulators",
        "abstract": "A Nature Research Journal",
        "keywords": "",
        "authors": [
            {
                "name": "J. Luo",
                "org": "Key Laboratory for Laser Plasmas (Ministry of Education) and Department of Physics and Astronomy, Shanghai Jiao Tong University, Shanghai, 200240, China"
            },
            {
                "name": "M. Chen",
                "org": "Key Laboratory for Laser Plasmas (Ministry of Education) and Department of Physics and Astronomy, Shanghai Jiao Tong University, Shanghai, 200240, China"
            },
            {
                "name": "M. Zeng",
                "org": "Key Laboratory for Laser Plasmas (Ministry of Education) and Department of Physics and Astronomy, Shanghai Jiao Tong University, Shanghai, 200240, China"
            },
            {
                "name": "L. L. Yu",
                "org": "Key Laboratory for Laser Plasmas (Ministry of Education) and Department of Physics and Astronomy, Shanghai Jiao Tong University, Shanghai, 200240, China"
            },
            {
                "name": "S. M. Weng",
                "org": "Key Laboratory for Laser Plasmas (Ministry of Education) and Department of Physics and Astronomy, Shanghai Jiao Tong University, Shanghai, 200240, China"
            },
            {
                "name": "Z. M. Sheng",
                "org": "Key Laboratory for Laser Plasmas (Ministry of Education) and Department of Physics and Astronomy, Shanghai Jiao Tong University, Shanghai, 200240, China"
            },
            {
                "name": "J. Zhang",
                "org": "Key Laboratory for Laser Plasmas (Ministry of Education) and Department of Physics and Astronomy, Shanghai Jiao Tong University, Shanghai, 200240, China"
            },
            {
                "name": "J. Luo",
                "org": "Collaborative Innovation Center of IFSA (CICIFSA), Shanghai Jiao Tong University, Shanghai, 200240, China"
            },
            {
                "name": "M. Chen",
                "org": "Collaborative Innovation Center of IFSA (CICIFSA), Shanghai Jiao Tong University, Shanghai, 200240, China"
            },
            {
                "name": "M. Zeng",
                "org": "Collaborative Innovation Center of IFSA (CICIFSA), Shanghai Jiao Tong University, Shanghai, 200240, China"
            },
            {
                "name": "L. L. Yu",
                "org": "Collaborative Innovation Center of IFSA (CICIFSA), Shanghai Jiao Tong University, Shanghai, 200240, China"
            },
            {
                "name": "S. M. Weng",
                "org": "Collaborative Innovation Center of IFSA (CICIFSA), Shanghai Jiao Tong University, Shanghai, 200240, China"
            },
            {
                "name": "Z. M. Sheng",
                "org": "Collaborative Innovation Center of IFSA (CICIFSA), Shanghai Jiao Tong University, Shanghai, 200240, China"
            },
            {
                "name": "J. Zhang",
                "org": "Collaborative Innovation Center of IFSA (CICIFSA), Shanghai Jiao Tong University, Shanghai, 200240, China"
            },
            {
                "name": "J. Vieira",
                "org": "GoLP/Instituto de Plasmas e Fusao Nuclear, Instituto Superior Tecnico, Universidade de Lisboa, Lisbon, 1049-001, Portugal"
            },
            {
                "name": "L. O. Silva",
                "org": "GoLP/Instituto de Plasmas e Fusao Nuclear, Instituto Superior Tecnico, Universidade de Lisboa, Lisbon, 1049-001, Portugal"
            },
            {
                "name": "D. A. Jaroszynski",
                "org": "SUPA, Department of Physics, University of Strathclyde, Glasgow, G4 0NG, UK"
            },
            {
                "name": "Z. M. Sheng",
                "org": "SUPA, Department of Physics, University of Strathclyde, Glasgow, G4 0NG, UK"
            }
        ],
        "venue": "Scientific Reports",
        "year": 2016
    },
    "AjtGMC76": {
        "id": "AjtGMC76",
        "title": "Laser-driven powerful kHz hard x-ray source",
        "abstract": "Abstract   A powerful hard x-ray source based on laser plasma interaction is developed. By introducing the kHz, 800 nm pulses onto a rotating molybdenum (Mo) disk target, intense Mo K α  x-rays are emitted with suppressed bremsstrahlung background. Results obtained with different laser intensities suggest that the dominant absorption mechanism responsible for the high conversion efficiency is vacuum heating (VH). The high degree of spatial coherence is verified. With the high average flux and a source size comparable to the laser focus spot, absorption contrast imaging and phase contrast imaging are carried out to test the imaging capability of the source. Not only useful for imaging application, this compact x-ray source is also holding great potential for ultrafast x-ray diffraction (XRD) due to the intrinsic merits such as femtosecond pulse duration and natural synchronization with the driving laser pulses.",
        "keywords": "",
        "authors": [
            {
                "name": "Minghua Li",
                "org": "Beijing National Laboratory of Condensed Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing 100190, China"
            },
            {
                "name": "Kai Huang",
                "org": "Beijing National Laboratory of Condensed Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing 100190, China"
            },
            {
                "name": "Liming Chen",
                "org": "Beijing National Laboratory of Condensed Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing 100190, China"
            },
            {
                "name": "W. C. Yan",
                "org": "Beijing National Laboratory of Condensed Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing 100190, China"
            },
            {
                "name": "Mengze Tao",
                "org": "Beijing National Laboratory of Condensed Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing 100190, China"
            },
            {
                "name": "Jiarui Zhao",
                "org": "Beijing National Laboratory of Condensed Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing 100190, China"
            },
            {
                "name": "Yong Ma",
                "org": "Beijing National Laboratory of Condensed Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing 100190, China"
            },
            {
                "name": "Yifei Li",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": "Key Laboratory for Laser Plasmas (MOE) and Department of Physics and Astronomy, Shanghai Jiao Tong University, Shanghai 200240, China"
            }
        ],
        "venue": "Radiation Physics and Chemistry",
        "year": 2017
    },
    "jb5e87bn": {
        "id": "jb5e87bn",
        "title": "Novel Emitting‐Color Tunable Phosphors Ba3Y2(BO3)4:Ce3+,Tb3+ with Efficient Energy Transfer for Near‐UV Light‐Emitting Diodes",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "bing han",
                "org": "zhengzhou university of light industry"
            },
            {
                "name": "jie zhang",
                "org": "zhengzhou university of light industry"
            },
            {
                "name": "yinhua lu",
                "org": "zhengzhou university of light industry"
            }
        ],
        "venue": "Journal of the American Ceramic Society",
        "year": 2013
    },
    "GE38GAuM": {
        "id": "GE38GAuM",
        "title": "Luminescent properties of SrBPO5:Dy3+ and effect of Co-doping with Tm3+",
        "abstract": "A series of phosphors SrBPO5:Dy3+ and SrBPO5:Dy3+,Tm3+ was synthesized by traditional solid-state high-temperature method and was characterized by X-ray diffraction (XRD) and fluorescence spectrophotometry. For SrBPO5:Dy3+ material, the f-f transitions of Dy3+ ions were assigned and discussed, and the optimal doping concentration of Dy3+ was found. As a result of co-doping SrBPO5:Dy3+ with Tm3+, the phosphors SrBPO5:Dy3+,Tm3+ can be effectively excited by 360 nm ultraviolet (UV), and exhibit color-tunable emission from blue to yellowish-white region with different doping concentration. The present study can pave the way for the creation of efficient UV phosphors using Dy3+,Tm3+ co-doped systems for near-UV InGaN-based light emitting diodes (LEDs).",
        "keywords": [
            "optical materials",
            " photoluminescence spectroscopy",
            " optical properties",
            " luminescence"
        ],
        "authors": [
            {
                "name": "bing han",
                "org": "zhengzhou university of light industry"
            },
            {
                "name": "jie zhang",
                "org": "zhengzhou university of light industry"
            },
            {
                "name": "yinhua lu",
                "org": "zhengzhou university of light industry"
            },
            {
                "name": "yan liu",
                "org": "zhengzhou university of light industry"
            },
            {
                "name": "qiao cui",
                "org": "zhengzhou university of light industry"
            }
        ],
        "venue": "Russian Journal of Physical Chemistry A",
        "year": 2013
    },
    "c2tNMo56": {
        "id": "c2tNMo56",
        "title": "Spectroscopic characteristic of Ce3+ at two different sites in Ba3Lu(BO3)3 under ultraviolet excitation",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "bing han",
                "org": "zhengzhou university of light industry"
            },
            {
                "name": "jie zhang",
                "org": "zhengzhou university of light industry"
            },
            {
                "name": "zhimeng wang",
                "org": "zhengzhou university of light industry"
            },
            {
                "name": "yuanyuan liu",
                "org": "zhengzhou university of light industry"
            }
        ],
        "venue": "Optics and Spectroscopy",
        "year": 2014
    },
    "KCZ3WNvt": {
        "id": "KCZ3WNvt",
        "title": "Investigation on the concentration quenching and energy transfer of red-light-emitting phosphor Y2MoO6:Eu3+",
        "abstract": "A series of phosphors Y2MoO6:Eu3+ with different Eu3+ contents were synthesized using a solid-state reaction technique at high-temperature. The phase purity, surface morphology, compositional and elemental analysis as well as photoluminescence properties were investigated by X-ray diffraction (XRD), scanning electron microscopic (SEM), fourier transform infrared (FT-IR), energy dispersive X-ray spectra (EDS), and fluorescence spectroscopy (FS) measurements, respectively. The luminescence characteristics in the excitation and emission spectrum were studied and analyzed, and the schematic diagrams of energy transfer of Y 2MoO6:Eu3+ was structured. The efficient energy transfer from Mo6+-O2- group to Eu3+ leads to the red light emission of Eu3+ upon near ultraviolet excitation. The influence of the doping concentration on the relative emission intensity of Eu3+ was investigated. The critical distance Rc and energy transfer mechanism for the concentration quenching of Eu3+ was calculated and discussed in details. ? 2014 Elsevier B.V.",
        "keywords": [
            "Eu 3+",
            "Optical properties",
            "Powders: solid state reaction",
            "Spectroscopy"
        ],
        "authors": [
            {
                "name": "Bing Han",
                "org": "Zhengzhou University(Zhengzhou University),Zhengzhou,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Zhengzhou University(Zhengzhou University),Zhengzhou,China"
            },
            {
                "name": "Zhimeng Wang",
                "org": "Zhengzhou University(Zhengzhou University),Zhengzhou,China"
            },
            {
                "name": "Yuanyuan Liu",
                "org": "Zhengzhou University(Zhengzhou University),Zhengzhou,China"
            },
            {
                "name": "Hengzhen Shi",
                "org": "Zhengzhou University(Zhengzhou University),Zhengzhou,China"
            }
        ],
        "venue": "Journal of Luminescence",
        "year": 2014
    },
    "Xs0z3jpN": {
        "id": "Xs0z3jpN",
        "title": "Luminescence properties of novel yellowish-green-emitting phosphor KBaBP 2 O 8 :Tb 3+ : Luminescence properties of yellowish green emitting phosphor KBaBP 2 O 8 :Tb 3+",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "hengzhen shi",
                "org": ""
            },
            {
                "name": "pengju li",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "bing han",
                "org": ""
            }
        ],
        "venue": "Physica Status Solidi (a)",
        "year": 2014
    },
    "ex3dufEc": {
        "id": "ex3dufEc",
        "title": "Luminescence properties of novel yellowish‐green‐emitting phosphor KBaBP2O8:Tb3+",
        "abstract": "",
        "keywords": [
            "terbium",
            "doping",
            "luminescence",
            "phosphors"
        ],
        "authors": [
            {
                "name": "bing han",
                "org": "zhengzhou university of light industry"
            },
            {
                "name": "jie zhang",
                "org": "zhengzhou university of light industry"
            },
            {
                "name": "pengju li",
                "org": "zhengzhou university of light industry"
            },
            {
                "name": "hengzhen shi",
                "org": "zhengzhou university of light industry"
            }
        ],
        "venue": "Physica Status Solidi (a)",
        "year": 2014
    },
    "oQ7TKCj9": {
        "id": "oQ7TKCj9",
        "title": "Spectroscopic Characteristic of Ce 3+ at Two Different Sites in Ba 3 Lu(BO 3 ) 3 Under Ultraviolet Excitation",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "yuanyuan liu",
                "org": ""
            },
            {
                "name": "zhimeng wang",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "bing han",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2014
    },
    "5YPXWOve": {
        "id": "5YPXWOve",
        "title": "Investigation on the concentration quenching and energy transfer of red-light-emitting phosphor Y 2 MoO 6 :Eu 3+",
        "abstract": "",
        "keywords": [
            "spectroscopy"
        ],
        "authors": [
            {
                "name": "bing han",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "zhimeng wang",
                "org": ""
            },
            {
                "name": "yuanyuan liu",
                "org": ""
            },
            {
                "name": "hengzhen shi",
                "org": ""
            }
        ],
        "venue": "Journal of Luminescence",
        "year": 2014
    },
    "ZEJEO5Xf": {
        "id": "ZEJEO5Xf",
        "title": "High color purity orange-emitting KBaBP 2 O 8 :Eu 3+ phosphor: Synthesis, characterization and photoluminescence properties",
        "abstract": "",
        "keywords": [
            "phosphor"
        ],
        "authors": [
            {
                "name": "bing han",
                "org": ""
            },
            {
                "name": "pengju li",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "hengzhen shi",
                "org": ""
            }
        ],
        "venue": "Journal of Luminescence",
        "year": 2014
    },
    "detHs478": {
        "id": "detHs478",
        "title": "Photoluminescence properties of novel yellowish orange emitting phosphor KBaBP 2 O 8 :Sm 3+",
        "abstract": "",
        "keywords": [
            "luminescence",
            "phosphor"
        ],
        "authors": [
            {
                "name": "bing han",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "pengju li",
                "org": ""
            },
            {
                "name": "hengzhen shi",
                "org": ""
            }
        ],
        "venue": "Materials Letters",
        "year": 2014
    },
    "LzmzOjW0": {
        "id": "LzmzOjW0",
        "title": "Photoluminescence properties of novel KBaBP2O8:M (M=Pb2+ and Bi3+) phosphors",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "bing han",
                "org": ""
            },
            {
                "name": "hengzhen shi",
                "org": ""
            },
            {
                "name": "yang bian",
                "org": ""
            },
            {
                "name": "jianliang li",
                "org": ""
            },
            {
                "name": "pengju li",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            }
        ],
        "venue": "Optical Materials",
        "year": 2014
    },
    "h467lKFT": {
        "id": "h467lKFT",
        "title": "A novel Sr3Y(PO4)3-based white light-emitting phosphor",
        "abstract": "Abstract The Sr3Y(PO4)3:0.05Sm3+, Sr3Y(PO4)3:0.005Tb3+, and Sr3Y(PO4)3:0.005Tb3+, 0.05Sm3+ phosphors were synthesized using a conventional solid-state reaction technique at high temperature and their photoluminescence properties under ultraviolet (UV) excitation were studied. We observed the UV sensitization of Sm3+ emission (565, 600, and 648 nm) by Tb3+ in Sr3Y(PO4)3:0.005Tb3+, 0.05Sm3+, that leads to a white light emission with the CIE coordinate (0.367, 0.312) of Sr3Y(PO4)3:0.005Tb3+, 0.05Sm3+ phosphor under UV excitation. The emission is a result of partial energy transfer from Tb3+ to Sm3+, which is discussed in detail in terms of the corresponding excitation and emission spectra.",
        "keywords": [
            "optical materials",
            "photoluminescence",
            "phosphor"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "School of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou, 450002, P.R. China"
            },
            {
                "name": "Bing Han",
                "org": "School of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou, 450002, P.R. China"
            }
        ],
        "venue": "Russian Journal of Physical Chemistry A",
        "year": 2014
    },
    "pLle7fr3": {
        "id": "pLle7fr3",
        "title": "Luminescence properties of novel single-host white-light-emitting phosphor KBaBP 2 O 8 :Dy 3+",
        "abstract": "A series of white-light-emitting KBaBP2O8:Dy3+ phosphors were synthesized by using a solid state reaction technique at high-temperature. X-ray diffraction and fluorescence spectroscopy measurements were utilized to characterize the structure and luminescence characteristics including excitation and emission spectra, decay curves, chromaticity coordinates of the assprepared phosphors. The influence of the doping concentration of Dy3+ on the relative emission intensity of Dy3+ was investigated. The critical distance as well as concentration quenching mechanism was calculated and confirmed. The as-prepared phosphors can be effectively excited with near ultraviolet, and exhibit white light emission with short decay time of milliseconds. The above work indicates these phosphors could be potential candidates as single-host white-light-emitting phosphors for application in white light-emitting-diodes.",
        "keywords": [
            "Emission Intensity",
            " Doping Concentration",
            " Solid State Reaction Technique",
            " White Light Emission",
            " Luminescence Decay Curve"
        ],
        "authors": [
            {
                "name": "Bing Han",
                "org": "School of Material and Chemical Engineering,Zhengzhou University of Light Industry,Zhengzhou,People’s Republic of China"
            },
            {
                "name": "Jie Zhang",
                "org": "School of Material and Chemical Engineering,Zhengzhou University of Light Industry,Zhengzhou,People’s Republic of China"
            },
            {
                "name": "Pengju Li",
                "org": "School of Material and Chemical Engineering,Zhengzhou University of Light Industry,Zhengzhou,People’s Republic of China"
            },
            {
                "name": "Hengzhen Shi",
                "org": "School of Material and Chemical Engineering,Zhengzhou University of Light Industry,Zhengzhou,People’s Republic of China"
            }
        ],
        "venue": "Optics and Spectroscopy",
        "year": 2015
    },
    "L4Esp1Kl": {
        "id": "L4Esp1Kl",
        "title": "Luminescence and energy transfer of emission tunable phosphors YBa 3 B 9 O 18 :Ce 3+ , Tb 3+",
        "abstract": "",
        "keywords": [
            "energy transfer",
            "phosphors",
            "luminescence"
        ],
        "authors": [
            {
                "name": "bing han",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "pengju li",
                "org": ""
            },
            {
                "name": "jianliang li",
                "org": ""
            },
            {
                "name": "yang bian",
                "org": ""
            },
            {
                "name": "hengzhen shi",
                "org": ""
            }
        ],
        "venue": "Optik",
        "year": 2015
    },
    "53baz9GZ": {
        "id": "53baz9GZ",
        "title": "Luminescence properties of Ce3+ in strontium borate SrB2O4",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "jie zhang",
                "org": "zhengzhou university of light industry"
            },
            {
                "name": "bing han",
                "org": "zhengzhou university of light industry"
            },
            {
                "name": "yingbo zhang",
                "org": "zhengzhou university of light industry"
            },
            {
                "name": "qi lv",
                "org": "zhengzhou university of light industry"
            }
        ],
        "venue": "Journal of Materials Science: Materials in Electronics",
        "year": 2015
    },
    "VxFdhhcj": {
        "id": "VxFdhhcj",
        "title": "Luminescence properties of novel single-host white-light-emitting phosphor KBaBP2O8:Dy3+",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "bing han",
                "org": "zhengzhou university of light industry"
            },
            {
                "name": "jie zhang",
                "org": "zhengzhou university of light industry"
            },
            {
                "name": "pengju li",
                "org": "zhengzhou university of light industry"
            },
            {
                "name": "hengzhen shi",
                "org": "zhengzhou university of light industry"
            }
        ],
        "venue": "Optics and Spectroscopy",
        "year": 2015
    },
    "XmB7PIbU": {
        "id": "XmB7PIbU",
        "title": "Luminescence properties of Ce3+ in strontium borate SrB2O4",
        "abstract": "Abstract A series of Ce3+-activated strontium borate SrB2O4 phosphors were prepared via high-temperature solid-state method, which were characterized by various characterization methods including X-ray diffraction, scanning electron microscopic, Fourier transform infrared spectra, and fluorescence spectroscopy measurements. The spectroscopic characteristics of Ce3+ in SrB2O4 host which include excitation/emission spectra, Stokes shift and crystal field depression were investigated and compared with that in other Sr based borates. The concentration dependent luminescence properties of Ce3+ were also discussed in detail.",
        "keywords": [],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "School of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou, 450002, People’s Republic of China"
            },
            {
                "name": "Bing Han",
                "org": "School of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou, 450002, People’s Republic of China"
            },
            {
                "name": "Yingbo Zhang",
                "org": "School of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou, 450002, People’s Republic of China"
            },
            {
                "name": "Qi Lv",
                "org": "School of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou, 450002, People’s Republic of China"
            }
        ],
        "venue": "Journal of Materials Science: Materials in Electronics",
        "year": 2015
    },
    "vRoJE5ly": {
        "id": "vRoJE5ly",
        "title": "Characterization and photoluminescence properties of sol-gel derived Bi2MoO6:Eu3+ phosphor",
        "abstract": "This work first reported the characterization and photoluminescence properties of Eu3+ doped Bi2MoO6 phosphor prepared by sol-gel method. The phosphor was characterized by X-ray diffraction, field emission scanning electron microscopic, fourier transform infrared spectrum, and fluorescence spectroscopy measurements in order to investigate the phase purity, surface morphology, and photoluminescence properties. The spectroscopic characteristics including excitation and emission spectrum, decay curve, and chromaticity coordinates were discussed. The as-prepared phosphor can be effectively excited with 345/465 nm light, and exhibit red emission belonging to the prevailing 5 D 0 → 7 F 2 transition of Eu3+ with decay time of milliseconds. The above spectral characteristics indicate sol-gel derived Bi2MoO6:Eu3+ phosphor could be regarded as a potential red phosphor for application in white light-emitting diodes (w-LEDs) based on ultraviolet (UV)/blue LED chips.",
        "keywords": [
            "Photoluminescence Property",
            " Solid State Lighting",
            " Bismuth Molybdate",
            " Broad Excitation Band",
            " Blue Lead Chip"
        ],
        "authors": [
            {
                "name": "jie zhang",
                "org": "zhengzhou university of light industry"
            },
            {
                "name": "bing han",
                "org": "zhengzhou university of light industry"
            },
            {
                "name": "pengju li",
                "org": "zhengzhou university of light industry"
            },
            {
                "name": "jianliang li",
                "org": "zhengzhou university of light industry"
            },
            {
                "name": "yang bian",
                "org": "zhengzhou university of light industry"
            }
        ],
        "venue": "Optics and Spectroscopy",
        "year": 2015
    },
    "p2iw87P3": {
        "id": "p2iw87P3",
        "title": "Ce3+→Tb3+ energy transfer induced emission-tunable properties of Ba3La(PO4)3:Ce3+,Tb3+ phosphors",
        "abstract": "Abstract   A series of Ce 3+ /Tb 3+  co-doped Ba 3 La(PO 4 ) 3  phosphors were synthesized successfully via a high-temperature solid-state reaction, and their luminescence properties were investigated. The energy transfer phenomenon of Ce 3+ →Tb 3+  in Ba 3 La(PO 4 ) 3  host was authenticated by relevant excitation spectra and decay curves, which leads to the change of luminous color for Ba 3 La(PO 4 ) 3 :Ce 3+ , Tb 3+  phosphors by tuning the quantity ratio of Ce 3+  and Tb 3+ . Meanwhile, the Ce 3+ →Tb 3+  energy transfer efficiencies were also calculated in this system. These results suggest that as-developed Ba 3 La(PO 4 ) 3 :Ce 3+ , Tb 3+  phosphors are potential single-component color-tunable phosphors.",
        "keywords": "",
        "authors": [
            {
                "name": "Bing Han",
                "org": "School of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou 450002, People's Republic of China"
            },
            {
                "name": "Jingtao Zhang",
                "org": "School of Food and Bioengineering, Zhengzhou University of Light Industry, Zhengzhou 450002, People's Republic of China"
            },
            {
                "name": "Bingkun Liu",
                "org": "School of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou 450002, People's Republic of China"
            },
            {
                "name": "Jie Zhang",
                "org": "School of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou 450002, People's Republic of China"
            },
            {
                "name": "Hengzhen Shi",
                "org": "School of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou 450002, People's Republic of China"
            }
        ],
        "venue": "Materials Letters",
        "year": 2016
    },
    "YgNS23G6": {
        "id": "YgNS23G6",
        "title": "Luminescence and energy transfer of Ba<Subscript>3</Subscript>P<Subscript>4</Subscript>O<Subscript>13</Subscript>:Ce<Superscript>3+</Superscript>and Ba<Subscript>3</Subscript>P<Subscript>4</Subscript>O<Subscript>13</Subscript>:Ce<Superscript>3+</Superscript>,Tb<Superscript>3+</Superscript> phosphors",
        "abstract": "A series of novel Ce3+ singly doped and Ce3+, Tb3+ co-doped Ba3P4O13 phosphors [Ba3P4O13:Ce3+, Ba3P4O13:Ce3+,Tb3+] were synthesized via the high-temperature solid-state reaction method. The photoluminescence properties and energy transfer behavior of the as-prepared phosphors were investigated in detail. The Ba3P4O13:Ce3+ phosphors produced broadband emission ranging from 300 to 400 nm upon UV excitation. The optimal concentration of Ce3+ and critical distance for Ce3+→Ce3+ energy transfer was ascertained by investigating the concentration dependent luminescence properties of Ce3+ in Ba3P4O13 host. The Ce3+→Tb3+ energy transfer phenomenon was proved to exist in the Ba3P4O13:Ce3+,Tb3+ phosphors, which led to the broadband sensitized yellowish-green emission of Ba3P4O13:Ce3+,Tb3+ phosphors upon UV excitation. The efficiency and mechanism of Ce3+→Tb3+ energy transfer was also investigated by theoretical calculation.",
        "keywords": "",
        "authors": [
            {
                "name": "Bing Han",
                "org": "School of Material and Chemical Engineering,Zhengzhou University of Light Industry,Zhengzhou,People’s Republic of China"
            },
            {
                "name": "Yazhou Dai",
                "org": "School of Material and Chemical Engineering,Zhengzhou University of Light Industry,Zhengzhou,People’s Republic of China"
            },
            {
                "name": "Jie Zhang",
                "org": "School of Material and Chemical Engineering,Zhengzhou University of Light Industry,Zhengzhou,People’s Republic of China"
            },
            {
                "name": "Hengzhen Shi",
                "org": "School of Material and Chemical Engineering,Zhengzhou University of Light Industry,Zhengzhou,People’s Republic of China"
            }
        ],
        "venue": "Journal of Materials Science: Materials in Electronics",
        "year": 2017
    },
    "aG4AnSXW": {
        "id": "aG4AnSXW",
        "title": "Synthesis and luminescence properties of a novel UV-emitting phosphor SrPO:Ce ",
        "abstract": "The ultraviolet (UV)-emitting Sr3P4O13:Ce3+ phosphors were synthesized via the solid-state reaction method, and their structural, morphological and luminescence properties were characterized by X-ray diffraction analysis, scanning electron microscopy, photoluminescence spectroscopy. The obtained results indicate that these phosphors can be effectively excited by short-wavelength ultraviolet (u003c300 nm), and exhibit long-wavelength ultraviolet (300–380 nm) emission with nanosecond-level fluorescence lifetime corresponding to the parity-allowed 5d–4f transitions of Ce3+. The concentration-quenching phenomenon of Ce3+ in Sr3P4O13 host was also studied, in which the critical energy transfer distance between Ce3+ ions and concentration quenching mechanism were determined.",
        "keywords": [
            "Luminescence Property",
            "Average Lifetime",
            "Luminescence Decay Curve",
            "Multipole Interaction",
            "Tetraphosphate"
        ],
        "authors": [
            {
                "name": "Bing Han",
                "org": "School of Material and Chemical Engineering,Zhengzhou University of Light Industry,Zhengzhou,People’s Republic of China"
            },
            {
                "name": "Yongfei Xue",
                "org": "School of Material and Chemical Engineering,Zhengzhou University of Light Industry,Zhengzhou,People’s Republic of China"
            },
            {
                "name": "Bingkun Liu",
                "org": "School of Material and Chemical Engineering,Zhengzhou University of Light Industry,Zhengzhou,People’s Republic of China"
            },
            {
                "name": "Jie Zhang",
                "org": "School of Material and Chemical Engineering,Zhengzhou University of Light Industry,Zhengzhou,People’s Republic of China"
            },
            {
                "name": "Hengzhen Shi",
                "org": "School of Material and Chemical Engineering,Zhengzhou University of Light Industry,Zhengzhou,People’s Republic of China"
            }
        ],
        "venue": "Journal of Materials Science: Materials in Electronics",
        "year": 2017
    },
    "412sHHKB": {
        "id": "412sHHKB",
        "title": "Concentration and temperature dependent luminescence properties of Gd 2 MoO 6 :Eu 3+ and white light generation from g-C 3 N 4 /Gd 2 MoO 6 :Eu 3+ composite phosphor",
        "abstract": "Abstract   The design and discovery of novel near-ultraviolet excitable phosphors has become a hot topic in academic research and practical applications, such as white light-emitting diodes for solid state lighting. The present work firstly reports the concentration/temperature dependent luminescence properties of the red emitting phosphor Gd 2 MoO 6 :Eu 3+ , synthesized by a typical solid state method. The as-prepared phosphor possesses a single monoclinic phase, as determined from XRD results. Upon excitation with near-ultraviolet light, the Gd 2 MoO 6 :Eu 3+  phosphor exhibits a characteristic red emission corresponding to the 4f-4f transitions of the Eu 3+  ions, in which the main electric dipole transition is  5 D 0  →  7 F 2 . In addition, the concentration quenching mechanism and the activation energy for thermal quenching of the Eu 3+  ions in Gd 2 MoO 6  host was also investigated in detail. Furthermore, a series of novel near-ultraviolet excitable emitting-color tunable composite phosphors consisted of graphitic-phase nitrogen carbon (g-C 3 N 4 ) and Gd 2 MoO 6 :Eu 3+  is reported herein. It is interesting that white light emission is veritably generated by compositing two luminescence materials at an appropriate weight ratio of g-C 3 N 4  to Gd 2 MoO 6 :Eu 3+ . The combination of an n-UV LED chip with the composite g-C 3 N 4 /Gd 2 MoO 6 :Eu 3+  phosphor produces white light with a CRI value of ∼80.1 and a CCT value of 4244 K. The obtained results indicate that the Gd 2 MoO 6 :Eu 3+  and g-C 3 N 4 /Gd 2 MoO 6 :Eu 3+  phosphors could be potential red and white emitting phosphors for application in white light-emitting diodes.",
        "keywords": "",
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "School of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou 450002, People’s Republic of China"
            },
            {
                "name": "Bing Han",
                "org": "School of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou 450002, People’s Republic of China"
            },
            {
                "name": "Pan Huang",
                "org": "School of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou 450002, People’s Republic of China"
            },
            {
                "name": "Juxin Yu",
                "org": "School of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou 450002, People’s Republic of China"
            },
            {
                "name": "Liang Zhao",
                "org": "School of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou 450002, People’s Republic of China"
            }
        ],
        "venue": "Polyhedron",
        "year": 2017
    },
    "GgBDRWFQ": {
        "id": "GgBDRWFQ",
        "title": "Luminescence properties of a novel yellow-emitting phosphor NaLaMgWO6:Dy3+",
        "abstract": "Abstract   A series of NaLaMgWO 6 :Dy 3+  phosphors were prepared by a conventional solid-state reaction method at high temperature. The phase structure, morphology, particle size distribution and concentration dependent luminescence properties of the phosphors were investigated for the first time. Upon excitation with UV (290 nm) and n-UV (388 nm), NaLaMgWO 6 :Dy 3+  phosphor exhibited typical Dy 3+  emission corresponding to the  4 F 9/2  →  6 H J  ( J  = 15/2, 13/2, 11/2) transitions of Dy 3+ , in which the hypersensitive electronic dipole transition  4 F 9/2  →  6 H 13/2  (575 nm) was with strongest emission intensity leading to the yellow emission with the CIE chromaticity coordinates (0.441, 0.475). The optimal concentration of Dy 3+  was found to be 8%. The luminescence decay lifetime for  4 G 5/2  →  6 H 13/2  transition of Dy 3+  was of millisecond level and decreased with the increase in Dy 3+  ion concentration. The obtained results indicated that NaLaMgWO 6 :Dy 3+  phosphor could be a potential yellow emitting phosphor for possible application in w-LEDs.",
        "keywords": "",
        "authors": [
            {
                "name": "Bing Han",
                "org": "School of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou 450002, People’s Republic of China"
            },
            {
                "name": "Yazhou Dai",
                "org": "School of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou 450002, People’s Republic of China"
            },
            {
                "name": "Jie Zhang",
                "org": "School of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou 450002, People’s Republic of China"
            },
            {
                "name": "Hengzhen Shi",
                "org": "School of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou 450002, People’s Republic of China"
            }
        ],
        "venue": "Materials Letters",
        "year": 2017
    },
    "iz4uHfFi": {
        "id": "iz4uHfFi",
        "title": "Luminescence quenching of Er3+/Sm3+ in color-tunable NaLaMgWO6:Er3+,Sm3+ phosphor",
        "abstract": "Abstract   A series of Er 3+  and Sm 3+  co-doped NaLaMgWO 6  phosphors were synthesized through high temperature solid state reaction, and their luminescence properties were investigated for the first time. According to the comparative photoluminescence excitation/emission spectra and decay curves, the energy transfer between Er 3+  and Sm 3+  in NaLaMgWO 6  host is proved to be invalid, but the mutually induced luminescence quenching phenomenon between Er 3+  and Sm 3+  is observed. Upon excitation with 260 nm and 379 nm, the as-prepared phosphors show tunable emission from green to red region dependent on the co-doped concentration of Er 3+  and Sm 3+ . The obtained results indicate that the NaLaMgWO 6 :Er 3+ ,Sm 3+  phosphor may have potential application as color-tunable phosphor in near-ultraviolet based white light emitting diodes.",
        "keywords": "",
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "School of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou 450002, People’s Republic of China"
            },
            {
                "name": "Yazhou Dai",
                "org": "School of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou 450002, People’s Republic of China"
            },
            {
                "name": "Beibei Liu",
                "org": "School of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou 450002, People’s Republic of China"
            },
            {
                "name": "Bing Han",
                "org": "School of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou 450002, People’s Republic of China"
            }
        ],
        "venue": "Optik",
        "year": 2018
    },
    "cl4NOCfz": {
        "id": "cl4NOCfz",
        "title": "Photoluminescence properties of Sm 3+ doped barium borophosphate phosphors",
        "abstract": "Abstract   In present work, a series of Sm 3+  doped barium borophosphate Ba 3−2x Sm x Na x BPO 7  (x = 0.01, 0.02, 0.03, 0.05, 0.07, and 0.1) phosphors were prepared via conventional solid-state reaction at high-temperature, and their structural and photoluminescence properties were investigated. The obtained XRD patterns were well consistent with ICSD No.150328, indicating the formation of pure phase. When excited with 404 nm light, the as-prepared phosphors generate orange red light due to the sharp emission peaks of Sm 3+  ions centered at 565 nm, 604 nm, 647 nm, 711 nm, which are ascribed to  4 G 5/2  →  6 H 5/2 ,  4 G 5/2  →  6 H 7/2 ,  4 G 5/2  →  6 H 9/2 , and  4 G 5/2  →  6 H 11/2  transitions of Sm 3+  ion, respectively. The strongest emission is located at 604 nm, which is with millisecond-level decay lifetime. The optimal doping concentration of Sm 3+  is confirmed to be x = 0.03, beyond which the typical concentration quenching phenomenon of Sm 3+  happens due to the electric multipole-multipole interaction. All of the results indicate that the as-prepared phosphor is a potential candidate as orange red phosphor for application in white light emitting diodes (w-LEDs).",
        "keywords": "",
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "School of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou 450002, People’s Republic of China"
            },
            {
                "name": "Chong Chen",
                "org": "School of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou 450002, People’s Republic of China"
            },
            {
                "name": "Xingang Zhang",
                "org": "School of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou 450002, People’s Republic of China"
            },
            {
                "name": "Xiaoyu Wang",
                "org": "School of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou 450002, People’s Republic of China"
            },
            {
                "name": "Wenhua Shi",
                "org": "School of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou 450002, People’s Republic of China"
            },
            {
                "name": "Bing Han",
                "org": "School of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou 450002, People’s Republic of China"
            }
        ],
        "venue": "Optik",
        "year": 2018
    },
    "3icSEQqC": {
        "id": "3icSEQqC",
        "title": "Orange emission of Sm3+ in a double phosphate KMgLa(PO4)2 under near-ultraviolet excitation",
        "abstract": "Abstract   A series of KMgLa(PO 4 ) 2 :Sm 3+  phosphors were synthesized by a conventional high-temperature solid state method, and their luminescence properties including excitation/emission spectra, decay curve and CIE chromaticity coordinates were investigated. Upon excitation with near-ultraviolet (402 nm), KMgLa(PO 4 ) 2 :Sm 3+  phosphor exhibited four groups of emission peaks corresponding to the  4 G 5/2  →  6 H J  ( J  = 5/2, 7/2, 9/2, and 11/2) transitions of Sm 3+ , in which the  4 G 5/2  →  6 H 7/2  transition at 597 nm is predominant leading to the orange emission. The emission intensity increases with the increasing concentration of Sm 3+  up to x = 0.05, then decreases due to the concentration quenching effect induced by the dipole–dipole interaction. The current investigation indicated that KMgLa(PO 4 ) 2 :Sm 3+  phosphor could be a potential orange component for application in w-LEDs.",
        "keywords": "",
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "School of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou 450002, People’s Republic of China"
            },
            {
                "name": "Yazhou Dai",
                "org": "School of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou 450002, People’s Republic of China"
            },
            {
                "name": "Pan Huang",
                "org": "School of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou 450002, People’s Republic of China"
            },
            {
                "name": "Juxin Yu",
                "org": "School of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou 450002, People’s Republic of China"
            },
            {
                "name": "Liang Zhao",
                "org": "School of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou 450002, People’s Republic of China"
            },
            {
                "name": "Bing Han",
                "org": "School of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou 450002, People’s Republic of China"
            }
        ],
        "venue": "Optik",
        "year": 2018
    },
    "VDP2p9Of": {
        "id": "VDP2p9Of",
        "title": "Development of near-ultraviolet-excitable single-phase white-light-emitting phosphor KBaY(BO 3 ) 2 :Ce 3+ ,Dy 3+ for phosphor-converted white light-emitting-diodes",
        "abstract": "Abstract   The development of near-ultraviolet (n-UV)-excitable single-phase white-light-emitting phosphor is highly meaningful for phosphor-converted white light-emitting-diodes (pc-WLEDs) based on n-UV chips. In this work, a series of Dy 3+  singly doped and Ce 3+ , Dy 3+  co-doped KBaY(BO 3 ) 2  phosphors with different doping concentration of Ce 3+ /Dy 3+  were designed and synthesized via a solid state reaction at high temperature, and their phase structure, photoluminescence properties and potential application in WLEDs were investigated in detail. The prominent sensitization effect of Ce 3+  on Dy 3+ -luminescence based on Ce 3+ →Dy 3+  energy transfer is authenticated by comparatively investigating the photoluminescence excitation and emission spectra of the as-prepared phosphors. The critical distance, efficiency, and mechanism of Ce 3+ →Dy 3+  energy transfer are calculated and determined in term of the theoretical formulas. The n-UV-excitable white light emission is realized in the KBaY(BO 3 ) 2 :Ce 3+ ,Dy 3+  phosphors with the appropriate doping concentration of Ce 3+  and Dy 3+  ions. A pc-WLEDs device is successfully fabricated by the combination of the single-phase KBaY(BO 3 ) 2 :Ce 3+ ,Dy 3+  phosphor and an n-UV (~365 nm) LED chip. All these properties indicate that the developed single-phase KBaY(BO 3 ) 2 :Ce 3+ ,Dy 3+  phosphor may have potential application prospect for pc-WLEDs.",
        "keywords": "",
        "authors": [
            {
                "name": "Bing Han",
                "org": "School of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou 450002, People's Republic of China"
            },
            {
                "name": "Yazhou Dai",
                "org": "School of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou 450002, People's Republic of China"
            },
            {
                "name": "Jie Zhang",
                "org": "School of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou 450002, People's Republic of China"
            },
            {
                "name": "Beibei Liu",
                "org": "School of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou 450002, People's Republic of China"
            },
            {
                "name": "Hengzhen Shi",
                "org": "School of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou 450002, People's Republic of China"
            }
        ],
        "venue": "Ceramics International",
        "year": 2018
    },
    "wdT6s19U": {
        "id": "wdT6s19U",
        "title": "Luminescence properties of Er3+-doped NaLaMgWO6 green-emitting phosphor and its luminescence optimization utilizing alkali metal ion substitution strategy",
        "abstract": "A series of trivalent erbium ion (Er3+) doped NaLaMgWO6 green-emitting phosphors with different doping concentration were prepared by a traditional solid-state reaction at high temperature, and their structural and luminescence properties were investigated in detail. Upon excitation with near ultraviolet (379 nm), the as-prepared phosphors exhibited the dominated green emissions, in which the 4S3/2 → 4I15/2 transition (544 nm) was with the highest intensity. The optimal concentration of Er3+ was confirmed to be 0.03, beyond which the concentration quenching phenomenon of Er3+ occurred due to the electric dipole–dipole interaction between the neighboring Er3+ ions. The decay lifetime for 4S3/2 → 4I15/2 transition of Er3+ was of microsecond level and decreased monotonously with the increasing Er3+ ion concentration. The alkali metal ion substitution strategy was also utilized to improve the green emissions of NaLaMgWO6:Er3+ phosphor by replacing Na+ with K+/Li+. This present work is helpful for the development of novel green-emitting phosphors for the potential application in white light-emitting diodes.",
        "keywords": "",
        "authors": [
            {
                "name": "Bing Han",
                "org": "School of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou, People’s Republic of China"
            },
            {
                "name": "Yazhou Dai",
                "org": "School of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou, People’s Republic of China"
            },
            {
                "name": "Beibei Liu",
                "org": "School of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou, People’s Republic of China"
            },
            {
                "name": "Jie Zhang",
                "org": "School of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou, People’s Republic of China"
            },
            {
                "name": "Hengzhen Shi",
                "org": "School of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou, People’s Republic of China"
            }
        ],
        "venue": "Journal of Materials Science: Materials in Electronics",
        "year": 2018
    },
    "vxrE7huW": {
        "id": "vxrE7huW",
        "title": "Touristic ecological footprint model and analysis of Huangshan City in 2002",
        "abstract": "Based on the theory and method of ecological footprint, combined with the ecological consumption and its structural character of tourist, the paper, taking the Huangshan City as an example, calculates and analyses the touristic ecological footprint and its efficiency of Huangshan City in 2002. Six characteristics have been summarized: (1) The touristic ecological footprint of Huangshan City is 0.106 hm2 per capita in 2002. In comparison, the fossil energy land is about 88.23% of this footprint, tourist transportation and food are the main constitutes of the total footprint, about 55.67% and 33.90%. (2) The ecological deficit of Huangshan City is 0.219 hm2 per capita in 2002. About 48.40% of the ecological deficit is a result of touristic ecological footprint. (3) Extrapolating the footprint of a tourist to Huangshan City (3.13 days) to 1 year, results in an area of 12.36 hm 2 per capita in 2002, almost 9 times that of the average footprints of citizens of Huangshan City. (4) In Huangshan City, the average tourist output of 1 hm2 ecological footprint is US$684, 1.17 times the average output of the Huangshan City' citizens ecological footprint, 61.84% that of the world. (5) Dimensions of tourist flows, tourist consumption level and model, tourist spatial behavior, the policy and stratagem of the tourist destination are the key factors to affect the size of touristic ecological footprint. (6) The shift of TEF among regions will result in shift and diffusibility of tourist ecological responsibility, ecological influence and ecological stress among regions in the world, and tourism development may have profound impacts on global environments.",
        "keywords": [
            "Ecological footprint",
            "Huangshan City",
            "Model",
            "Tourism sustainable development",
            "Touristic ecological footprint"
        ],
        "authors": [
            {
                "name": "Jinhe Zhang",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            }
        ],
        "venue": "Acta Geographica Sinica",
        "year": 2004
    },
    "V2y1789w": {
        "id": "V2y1789w",
        "title": "A study on weathering processes of Leshan Grand Buddha,Sichuan,China",
        "abstract": "Leshan Grand Buddha is one of the most important heritage resources of the World Heritage of Culture and Nature in China,which is located in Lingyun Mountains at Leshan,Sichuan province,China.The surface weathering problem of the carved stone is very serious,and how to protect it from the bad weathering is a difficult task.Therefore,this paper studies on the surface weathering problems of the siltstone in Lingyun Mountains,where Leshan Grand Buddha is located,in order to get more deterioration information about the carved stones. The test results of the siltstone samples with the X-ray Fluorescence Spectrometry(XRFS) indicated that the SiO_2 is the main component and its quality percentage is up to 84%,the next parts are Al_2O_3 of 7.5% and Fe_2O_3 of 1.7%,etc.In addition,the siltstone includes a great deal of quartz powder,most of its diameter is around 0.250mm,and the other is the mauve cementation. In order to measure the erosion rates of the siltstone,we installed four suits of micro-erosion meter(MEM) instruments based on the principle of screwing measurement.The results indicated that the erosion thickness is mostly close 0.216-0.303mm of the year.We also investigated the environmental factors besides the experiment and found that water and biological intrusions are two important factors affecting the erosion rates. At the locale,we also tested the rigidity of the siltstone surfaces too with grout rebound instrument(ZC5 Model),which proved that siltstone weathering is faster than that of limestone because of the very low rigidity.The surface rigidity of siltstone will reduce quickly and become soft once it touches water,so the siltstone surface is easy to be destroyed by environmental factors. Therefore we can conclude that the Leshan Grand Buddha will go on weathering because the siltstone rocks has loose structure,and siltstone surface can be ruined easily.The good natural environment such as water vapor from the river,complex components of the siltstone cementation conditions is favorable for the microorganism and plants to grow.Therefore,water and bio-environment are important external factors accelerating the heritage surface deterioration and the fundamental internal factor is the unstable structure of the quartz grain and cementation system.",
        "keywords": [
            "stone heritage",
            "siltstone",
            "erosion rates",
            "Leshan Grand Buddha"
        ],
        "authors": [
            {
                "name": "QIN Zhong",
                "org": "Department of Urban and Resources Sciences,Nanjing University,Nanjing ,China;Engineering college of Resources and Environment,Guizhou University,Guiyang ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Urban and Resources Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "PENG Xue-yi",
                "org": "Wuyou Heritage Safeguard Bureau,Leshan Grand Buddha,Leshan ,China"
            },
            {
                "name": "WANG Xing-shan",
                "org": "Department of Urban and Resources Sciences,Nanjing University,Nanjing ,China"
            }
        ],
        "venue": "Geographical Research",
        "year": 2005
    },
    "jN0wZORW": {
        "id": "jN0wZORW",
        "title": "A tourist destination choice model based on Lancasterian characteristics theory and destination image theory:theoretical analysis and case study",
        "abstract": "The processes of tourism destination choice are influenced by both psychological variables(motivations,attitudes,beliefs and images) and non-psychological variables(time,destination attributes,perceived costs of tourism product,buyer characteristics and benefits sought).As tourism is an experience,it includes many intangible attributes,and does not offer the chances of trial experience.Tourist image affected by both stimulus elements of the product and the characteristics of the perceiver is a valuable concept in understanding the destination selection process.The inclusion of product characteristics or attributes in tourism analysis appears to strongly contribute towards the better understanding of travel choice behaviour.However,the traditional demand theory ignores the particularities of the product and the existing demand models exclude measures of traveller's attitudes including perceptions of service attributes and personal feelings toward different destinations and/or services.Therefore,despite its contribution to tourism research,the traditional demand theory is insufficient to justify comprehensively the direction of tourist flows in space and time.To address these issues,the paper has provided a conceptual mode and analysis model of tourism destination choice based on Lancasterian product characteristic theory and tourist destination image theory,which extends further the Lancaster product characteristic framework as applied to tourism.And the estimation of tourist preference ordering by utilising a conditional Logit analysis has been discussed.With the proposed model the characteristics of the tourism product/destination combined to generate a perception/feeling regarding the tourism destination in the mind of the tourists.Finally the conditional Logit model generates the probability of revisit given the characteristics of tourists and the Jiangxi tourism product.Because of the inter-disciplinary character of the research and the knowledge limits of the author,there are many areas in the research that deserve further to study,especially the application of the Lancasterian theory in tourist development and plan.",
        "keywords": [
            "Logit analysis",
            "tourist destination image",
            "tourism destination choice",
            "Lancasterian characteristic theory"
        ],
        "authors": [
            {
                "name": "MAO Duan-qian",
                "org": "Dept.of Urban & Resources,Nanjing University,Nanjing ,China;Dept.of Geography,Jiangxi Normal University,Nanchang ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Dept.of Urban & Resources,Nanjing University,Nanjing ,China"
            },
            {
                "name": "BAO Hao-sheng",
                "org": "Dept.of Urban & Resources,Nanjing University,Nanjing ,China"
            }
        ],
        "venue": "Geographical Research",
        "year": 2005
    },
    "5D0VYYU4": {
        "id": "5D0VYYU4",
        "title": "Environmental Awareness Analysis of Tourists and Its Implication for the Management of Scenic Area——A Case Study of Jiuzhaigou Natural Reserve",
        "abstract": "Tourists with different environmental awareness have different environmental impact on the scenic area.Through the(application) of SPSS and the foundation of an analytic model,this article analyses the data of tourists′ environmental awareness which were collected in Jiuzhaigou Nature Reserve,and gives out the characteristics of environmental awareness of different groups of tourists.At last,some suggestions based on the analysis are put forward for the environmental management of the scenic area.",
        "keywords": [
            "Jiuzhaigou Natural Reserve",
            "Tourist",
            "environmental awareness"
        ],
        "authors": [
            {
                "name": "ZHANG Hong-qiao",
                "org": "Department of Urban and Resources Science,Nanjing University,Nanjing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Urban and Resources Science,Nanjing University,Nanjing ,China"
            },
            {
                "name": "CHEN You-jun",
                "org": "Department of Urban and Resources Science,Nanjing University,Nanjing ,China"
            },
            {
                "name": "LIANG Li",
                "org": "Department of Urban and Resources Science,Nanjing University,Nanjing ,China"
            }
        ],
        "venue": "Sichuan Environment",
        "year": 2005
    },
    "wzw0yjCk": {
        "id": "wzw0yjCk",
        "title": "Zipf structure and difference degree of tourist flow size system: A case study of Sichuan province",
        "abstract": "The Zipf theory is the law to study the relation between word frequency and word sequence which is now extensively used in city size structure, city spatial fractal, economics, sociology, and so on. From supposition to discussion, this paper proves that tourist flow size grading structure is in conformity with the Zipf theory in aid of the Zipf and difference degree index. The scaling section feature and internal structural difference in each scaling range of domestic and inbound tourist flow size grading structure in Sichuan province were studied in this paper based on statistic data of domestic tourist flow from 1996 to 2004. The result shows that tourist flow size grading structure has possessed the Zipf feature, even could be sectioned by fractal dimension scaling in certain years, and the bifurcation points of each scaling range can be determined by regression equations. The scaling section may be divided into two types, which are effective and ineffective scaling sections. Viewing from the tourism development in Sichuan province, the space distribution area of tourist flow ineffective scaling section is reducing and effective scaling section area is increasing. The Zipf index can be used to divide the scope of each scaling section and analyze the internal structural feature of effective scaling section and the changing law of the tourist flow size grading structure. For the region without the unobvious Zipf feature, equilibrium degree and difference index can be used to study the difference of the internal structure. The study shows that the results of effective scaling section being analyzed by the Zipf index and ineffective scaling section by equilibrium degree and difference index accord with the objective reality, also clearly reflect the structure scaling section feature, the internal structural difference of each section and the changing law of the total structure system. This is very important to enrich the methods of analyzing tourist flow size grading structure. Concerning the tourist flow size structure in Sichuan province, the Zipf index \"q\" of domestic tourist flow is mostly between one and two before 2002, and the size grading structure system assumes Pareto distribution pattern; after 2003, the Zipf index \"q\" further reduces and the tourist flow size structure is turning to logarithmic regular distribution pattern.",
        "keywords": [
            "Difference degree",
            "Scaling range",
            "Sichuan province",
            "Size structure",
            "Tourist flow",
            "Zipf"
        ],
        "authors": [
            {
                "name": "Guoliang Yang",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Nanshan Ai",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Bo Liu",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            }
        ],
        "venue": "Acta Geographica Sinica",
        "year": 2006
    },
    "SbC1ZlTB": {
        "id": "SbC1ZlTB",
        "title": "Study of Limestone Statuary on Base of Rigidity——A Case Study on Stone Statuary of Ming Dynasty in Nanjing",
        "abstract": "There are many cultures stone of Ming dynasty in Nanjing,all made of limestone.The paper divides the surface of culture stone into four types on base of overcast of diverse microorganism: nearly no overcast of microorganism,overcast of less microorganism,overcast of much microorganism,nearly all overcast of microorganism.And it uses schmit hammer to get their external rigidity and the connection between external rigidity and overcast extent of microorganism.It draws a qualitative conclusion of the connection of external microorganism: if culture stone is obvious of grain,then the external rigidity and the extent of overcast of microorganism is relational,others do not.",
        "keywords": [
            "Nanjing",
            "external rigidity",
            "overcast extent of organism",
            "stone statuary"
        ],
        "authors": [
            {
                "name": "WANG Xing-shan",
                "org": "Department of Urban and Resources Science,Nanjing University,Nanjing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Urban and Resources Science,Nanjing University,Nanjing ,China"
            },
            {
                "name": "QIN Zhong",
                "org": "Department of Urban and Resources Science,Nanjing University,Nanjing ,China"
            }
        ],
        "venue": "Journal of Anhui Normal University(Natural Science)",
        "year": 2006
    },
    "yFoamW6Q": {
        "id": "yFoamW6Q",
        "title": "Research on the Spatial Development Strategy of the integrated Tourism Region:A Case Study of integrated tourism region of Changjiang River Delta",
        "abstract": "This paper defines the conception of integrated tourism region firstly,and takes integrated tourism region of Changjiang River Delta as an example,makes a detailed study about the formation and evolution,spatial characteristic and spatial strategy of integrated tourism region.The study shows that the integrated course of integrated tourism region has the benefit for tourism elements' reset in bigger space,and could bring into more and more comparative benefit,reciprocal benefit and selective benefit.The construction of integrated tourism region contributes to promoting justified elements' configuration,leads to contiguous utility,separated utility,structural utility and conglomerated utility,achieves cogent spatial and industrial advantages,and ameliorates the structure of market and function.And then it could promote integration competitive abilities if the market member,field and mechanism are enlarged.",
        "keywords": [
            "Changjiang River Delta",
            "competitive ability strategy",
            "spatial character",
            "integrated tourism region"
        ],
        "authors": [
            {
                "name": "NIE Xian-Zhong",
                "org": "Department of City and Resource Sciences,Nanjing University,Nanjing,Jiangsu ;Institute of Economics Research,Zhejiang Provincial Academy of Social Science,Hangzhou,Zhejiang "
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of City and Resource Sciences,Nanjing University,Nanjing,Jiangsu "
            },
            {
                "name": "ZHANG Jin-He",
                "org": "Department of City and Resource Sciences,Nanjing University,Nanjing,Jiangsu "
            },
            {
                "name": "LIU Ze-Hua",
                "org": "Department of City and Resource Sciences,Nanjing University,Nanjing,Jiangsu "
            }
        ],
        "venue": "Scientia Geographica Sinica",
        "year": 2006
    },
    "qn8tkqPn": {
        "id": "qn8tkqPn",
        "title": "A Summary of Studies on Tourism Destination Collaboration and Prospect",
        "abstract": "In this paper,the authors make a summary of both abroad and domestic literatures on study of tourism destination collaboration,its research content includes destination collaboration conception and function,theory and method,type and operational model,evolution and phase characteristic,dynamic factor and mechanism.To compare with abroad studies,it is found that domestic studies are still at the initial stage and there remains a long distance between them.It is believed that Chinese destination collaboration in the future will focus on evolutional and operational mechanism of destination collaboration.And its research content,framework and method are put forward in the end.",
        "keywords": [
            "commentary",
            "tourism destination collaboration",
            "domestic studies",
            "abroad studies"
        ],
        "authors": [
            {
                "name": "YANG Xiao-zhong",
                "org": "Department of Urban and Resource Sciences,Nanjing University,Nanjing ;College of National Territorial Resources and Tourism,Anhui Normal University,Wuhu ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Urban and Resource Sciences,Nanjing University,Nanjing "
            }
        ],
        "venue": "Geography and Geo-Information Science",
        "year": 2006
    },
    "tGR6AQoP": {
        "id": "tGR6AQoP",
        "title": "An Application on Surface Processes of Carbonate Rocks",
        "abstract": "Carbonate rocks is an important,most familiar rocks in karst area and an excellent kind of materials applied in many industries too,but its surface instability has shown some disadvantage whiles main environmental factors,such as water,microorganism,etc.,erode the carbonate rocks surfaces chronically.It is necessary to discuss how the surface processes take place or how to maintain its stability so as to protect heritage resources.As a kind of heritage made from the carbonate rocks,the ineluctability always appears more or less to the surface processes in nature,which could also result in deterioration of heritage resources,therefore,the main reason come down to the erosion action of several factors.It would be a good idea to set protection layer to hold back the eroding force of environmental factors,but techniques research should be advanced in future.",
        "keywords": [
            "rock heritages",
            "stability",
            "protection layer",
            "surface of carbonate rocks",
            "karst rate"
        ],
        "authors": [
            {
                "name": "QIN Zhong",
                "org": "Key Laboratory of Karst Environment and Geological Hazard Prevention,Ministry of Education of P.R.China,Guizhou University,Guiyang ,China;College of Environment and Resources Engineering,Guizhou University,Guiyang ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Urban and Resources Science,Nanjing University,Nanjing ,China"
            },
            {
                "name": "LIU Pei",
                "org": "College of Environment and Resources Engineering,Guizhou University,Guiyang ,China"
            }
        ],
        "venue": "Journal of Guizhou University of Technology(Natural Science Edition)",
        "year": 2006
    },
    "5tVVQWmB": {
        "id": "5tVVQWmB",
        "title": "Research Progress and Model Modification of Ecological Footprint",
        "abstract": "Ecological footprint model is an important and effective way to measure sustainability,which based on the results of many ecological-economic studies in the 1970s.However,due to its inherent weakness,such as partial to ecological index,static state of ecological footprint calculation,partial to items of calculation,and failure to provide a cohesive analytical tool for sustainability management,many foreign scholars modified ecological footprint model according to its shortcomings.Today,overseas study on the ecological footprint model focus on nine research fields,namely,ecological footprints relating to different food consumption patterns,ecological footprints associated with different household income and spending,ecological footprints of international trade,ecological footprints exchange relief international debts,ecologically unequal exchange in trade activities,ecological footprints of circular economy,ecological footprints of energy supplies,ecological footprints by national economy progress,ecological footprints of passenger and commodities transportation systems,ecological footprints of special industries.Base on the review of the latest achievements and frontiers of overseas study,this paper suggests that the further research of ecological footprint model should be strengthened in four aspects: 1) calculation of time series ecological footprint and exploration of the relation between the ecological footprint and sustainable development;2) comparison of different dimensions of ecological footprint among regions;3) expansion of the application of ecological footprint in environmental,social and economic fields;4) modification and improvement of the ecological footprint model in China.",
        "keywords": [
            "A rich-country-illusion effect",
            "Circular economy",
            "Ecologically unequal exchange",
            "Ecological footprint",
            "Ecological rucksack",
            "Model modification"
        ],
        "authors": [
            {
                "name": "ZHANG Jin-he",
                "org": "Department of Urban and Resources Science,Nanjing University,Nanjing,,China;College of National Territorial Resources and Tourism,Anhui Normal University,Wuhu ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Urban and Resources Science,Nanjing University,Nanjing,,China"
            }
        ],
        "venue": "Resources Science",
        "year": 2006
    },
    "WzACJ9kP": {
        "id": "WzACJ9kP",
        "title": "Latest Progress on Research of Leisure in China",
        "abstract": "In reviewing the history of leisure research in the 1990s,this paper introduces the latest research interests in this area and the achievements made in China.It is found that the introduction of overseas leisure theories,the study of leisure economy and leisure industry,the time-and-space characteristics of leisure and recreation participants,leisure planning,and the impacts of leisure and recreation activities are the most popular research areas.The paper also includes future directions for research,such as the enrichment of the study of leisure and recreation,the improvement of research methods and the expansion of leisure research areas.",
        "keywords": [
            "leisure research",
            "past ten years",
            "progress and focus",
            "China"
        ],
        "authors": [
            {
                "name": "LIANG Yue-lin",
                "org": "Department of Urban and Resources Sciences,Nanjing University,Nanjing ,China;College of Management,China University of Geosciences,Wuhan ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Urban and Resources Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "ZHANG Jin-he",
                "org": "Department of Urban and Resources Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "LI Na",
                "org": "Department of Urban and Resources Sciences,Nanjing University,Nanjing ,China"
            }
        ],
        "venue": "Journal of China University of Geosciences(Social Sciences Edition)",
        "year": 2006
    },
    "8FEq66sU": {
        "id": "8FEq66sU",
        "title": "MEASURING AND ANALYSIS ON TOURISM COMPETITIVENESS:BASED ON WTTC DATA BASE",
        "abstract": "Based on the World Travel & Tourism Council Data Base,which provided eight main indexes of tourism competitiveness including Price Competitiveness,Openness,Technology,Infrastructure,Human Tourism,Social development,Environment and Human Resource of 207 countries,the paper undertook the research on the tourism competitiveness quantitatively using Principal Components Analysis,Hierarchical Cluster Analysis and Discriminant Analysis with SPSS software.The results suggested that Social Development,Human Resources and Technology had higher contributions while Infrastructure and Environment had fewer contributions to the tourism competitiveness.Integrative tourism competitiveness of all the countries had also been reckoned.Cluster Analysis had divided all the countries into four groups.Those in group one and two were all underdeveloped countries while all the developed countries were included in group three and four.Discriminant Analysis had correctly classified 98.1% of original grouped countries.The tourism competitiveness of China were also discussed and found that Price Competitiveness was the main strength while Human tourism and Infrastructure were the key weaknesses.Finally the problems needed to further study were put forward.",
        "keywords": [
            "measure",
            "WTTC data base",
            "tourism competitiveness"
        ],
        "authors": [
            {
                "name": "SHI Chun-yun",
                "org": "Department of Urban and Resources Sciences,Nanjing University,Nanjing ,Jiangsu,China;School of Urban and Environmental Sciences,Xuzhou Normal University,Xuzhou ,Jiangsu,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Urban and Resources Sciences,Nanjing University,Nanjing ,Jiangsu,China"
            },
            {
                "name": "ZHU Chuan-geng",
                "org": "School of Urban and Environmental Sciences,Xuzhou Normal University,Xuzhou ,Jiangsu,China"
            },
            {
                "name": "ZHOU Zhang",
                "org": "International Business School,Nanjing University,Nanjing ,Jiangsu,China"
            },
            {
                "name": "YANG Yang",
                "org": "Department of Urban and Resources Sciences,Nanjing University,Nanjing ,Jiangsu,China"
            }
        ],
        "venue": "Economic Geography",
        "year": 2006
    },
    "TWrOcosV": {
        "id": "TWrOcosV",
        "title": "AN OVERVIEW OF QUANTITIVE EVALUATION OF THE TOURIST DESTINATION COMPETITIVENESS",
        "abstract": "Although the tourist destination competitiveness(TDC) has been a hot topic among researchers,policymakers and practitioners in tourism industry at home and abroad in recent years,systematic studies on the quantitive evaluation have been still relatively rare.The purpose of this paper is to probe into the models,the selected variables,application,advantages and limitation,as well as the future study of the competitiveness evaluation by reviewing the relevant published theoretical and empirical studies.TDC is generally conceptualized both from the sustainable development of the destination and from the satisfaction of the tourist preference.However,TDC is a complex and a multidimensional concept encompassing various elements.Meanwhile TDC is also a relative concept and its measure depends on the choice of the different benchmarking. The main theoretical bases of TDC are comparative advantage theory and competitive advantage theory.Price,arrivals and receipts,tourist demand and preference,as well as environmental management are the variables that are mostly applied in the evaluation models.The famous Crouch & Ritchie comprehensive model of TDC is introduced and compared with Dwyer & Kim integrated model.The former has been applied to empirical studies while the latter is mainly based on and developed from the former and needs to testify with the further research.Two types of data,published data and survey data,are used in the empirical studies.Finally,the main issues for further research are discussed.",
        "keywords": [
            "tourist destination competitiveness",
            "evaluation methods",
            "evaluation models",
            "variables"
        ],
        "authors": [
            {
                "name": "SHI Chun-yun",
                "org": "Department of Urban and Resources Sciences,Nanjing University,Nanjing ,China;College of Urban and Environmental Sciences,Xuzhou Normal University,Xuzhou ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Urban and Resources Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "SHEN Zheng-ping",
                "org": "College of Urban and Environmental Sciences,Xuzhou Normal University,Xuzhou ,China"
            },
            {
                "name": "YANG Yang",
                "org": "Department of Urban and Resources Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "ZHONG Jing",
                "org": "Department of Urban and Resources Sciences,Nanjing University,Nanjing ,China"
            }
        ],
        "venue": "Human Geography",
        "year": 2006
    },
    "dAW6Xhsf": {
        "id": "dAW6Xhsf",
        "title": "Game Analysis of Stakeholders?' Actions on Utilization and Protection of Ecotourism Resources",
        "abstract": "The utilization and protection of ecotourism resources is a process in which stakeholders compromise and(cooperate) together.By analyzing the application of game theory to the interest of users and protectors of ecotourism resources,the(paper) discusses their reasons that the stakeholders overuse ecotourism resources and do not protect them efficiently,and also(indicates) how to set up a rule that can be actualized automatically and will become an endogenous effective resource(utilization) and protection system.Under certain conditions,the system will make every stakeholder comply with.",
        "keywords": [
            "Ecotourism resources",
            "driving force",
            "rule",
            "game"
        ],
        "authors": [
            {
                "name": "TANG Zong-wei",
                "org": "Department of Urban & Resources Science,Nanjing University,Nanjing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Urban & Resources Science,Nanjing University,Nanjing ,China"
            },
            {
                "name": "ZHANG Hong-qiao",
                "org": "Department of Urban & Resources Science,Nanjing University,Nanjing ,China"
            }
        ],
        "venue": "Sichuan Environment",
        "year": 2006
    },
    "lNG1viVZ": {
        "id": "lNG1viVZ",
        "title": "Correlation Analysis of Subject Content Frequerce and Research on the Succession Relationships of Past Dynasties Calligraphy Theory",
        "abstract": "Ancient Chinese literature with its variable writing style,terminology,citing format as well as elucidative model,is a field with difficulty to develop biliometric study.To counter this situation and with case materials of hundreds of ancient Chinese calligraphic aesthetic literatures,a solution based on the statistics of subject contents of natural image descriptions classified into 21 types as indices with time unit of dynasty,a subject content frequency regression analysis was undertaken on the evolution of the Chinese classic calligraphic aesthetics with respect to the field of relationships of succeeding or influence among the classics of different dynasties.The result implies that those classics of Southern Dynasty,Wei & Jin Dynasties and Sui & Tang Dynasties are classics of former dynasty with most influence on classics of later dynasties.As for the succeeding of the classics of later dynasties to the ones of former dynasties,classics of those pairs of dynasties are of most obvious ones,i.e.,Southern Dynasty to Wei and Jin Dynasties,Sui & Tang Dynasties to Southern Dynasty and Song Dynasty to Sui & Tang Dynasties.Quite many relationships among ancient classics were newly founded,and some of these phenomena can be identified with normal literature text research.Also,the historic status of the calligraphic theory of each dynasty was analyzed in the paper with their relationship to the theories of other dynasties as a whole.",
        "keywords": [
            "calligraphy theory",
            "description of natural image",
            "succession history",
            "subject content",
            "correlation analysis"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Department of City and Resource,Nanjing University,Nanjing ,China;Research Centre of East Painting and Calligraphy Art,Nanjing University,Nanjing ,China"
            },
            {
                "name": "RAO Wei",
                "org": "Library of Nanjing University,Nanjing ,China;Research Centre of East Painting and Calligraphy Art,Nanjing University,Nanjing ,China"
            },
            {
                "name": "WANG Xiao-lun",
                "org": "School of English Literature,Xi'an Institute of Foreign Language,Xi'an ,China"
            }
        ],
        "venue": "Information Science",
        "year": 2006
    },
    "OfEorQq0": {
        "id": "OfEorQq0",
        "title": "A Research on Tourism Regional Impact Based on the Features of Tourist Flows:A Case Study of Huai'an",
        "abstract": "Based on tourist flows,the paper did an indepth analysis of the mechanism of tourism regional Impacts which consists of three basic environmental mechanisms,and three basic spatial modes.It then formed a basic \"Mechanism-Model\" Impact matrix by mixing the mechanism and the modes together.With this matrix,the authors put forward an analysis frame of tourism impact on destination regions based on tourist flow and spatial perspectives.It used Huai'an as a case in point to analyze the frame empirically and the result shows that this analysis fame has theoretical and practical significances in guiding regional tourism development pactices.",
        "keywords": [
            "spatial model",
            "tourist flows",
            "\"Mechanism-Model\" matrix",
            "Huai'an",
            "impact mechanism"
        ],
        "authors": [
            {
                "name": "HUANG Tai",
                "org": "%%#~1 Institute of Social Science,Soochow University,Suzhou ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "%%#%%#~2 Institute of Geoscience,Nanjing University,Nanjing ,China"
            }
        ],
        "venue": "Tourism Science",
        "year": 2006
    },
    "mpcg5e49": {
        "id": "mpcg5e49",
        "title": "The Tourism Division Based on the Spatial Analysis of Attractions and the Accessibility of Market——An Example for Tourism Zone Along Yangtze River",
        "abstract": "This paper evaluates the tourism resources of tourism zone along Yangtze river based on of \"Chinese tourist resources general survey norm\",and makes use of the graph theory to analyze the spatial structure of the tourist resources,on the base of this quantitative research and foundation analyses synthetically,carry on the tourism division to the tourism resources of tourism zone along Yangtze river.",
        "keywords": [
            "traffic network",
            "graph theory",
            "resources evaluation",
            "tourism zone"
        ],
        "authors": [
            {
                "name": "LIU Ping-zhen",
                "org": "Department of Urban & Resource Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "LIANG Li",
                "org": "Department of Urban & Resource Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Urban & Resource Sciences,Nanjing University,Nanjing ,China"
            }
        ],
        "venue": "Henan Science",
        "year": 2006
    },
    "xJE2xKzb": {
        "id": "xJE2xKzb",
        "title": "Study on leisure image space structure of Wuhan city",
        "abstract": "Based on the questionnaire and on the spot investigation,the authors discuss the essential factors and image space structure of Wuhan city.The authors draw the following conclusions:(1) The essential factors of Wuchang,Hanyang and Hankou are not equivalent.(2) There is not a holistic leisure space image in Wuhan.And the centripetal leisure symbol has not appeared in Wuhan city.The author hopes that the results can be helpful to the planning and the reconstruction of urban leisure space in Wuhan city.",
        "keywords": [
            "leisure space",
            "image space",
            "essential factor",
            "Wuhan",
            "space structure"
        ],
        "authors": [
            {
                "name": "LIANG Yuelin",
                "org": "Department of Land Resources and Tourism Sciences,Nanjing University,Nanjing ;College of Management,China University of Geosciences,Wuhan "
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Land Resources and Tourism Sciences,Nanjing University,Nanjing "
            }
        ],
        "venue": "Journal of Huazhong Normal University(Natural Sciences)",
        "year": 2007
    },
    "TTReAirf": {
        "id": "TTReAirf",
        "title": "Core-periphery spatial structure and its evolution of tourism region in Sichuan Province",
        "abstract": "Core-periphery model is generally used as a theory to interpret the spatial discrepancy of regional development and evolvement pattern of regional economic structure. Core-periphery theory has been rarely put into the tourism research both at home and abroad. Previous work of empirical researches undertaken in tourism field has mainly focused on the economic inequality and developmental relationships between the core and the periphery tourism regions. However, the form and its evolvement of the spatial core-periphery structure are still relatively rare up to now. Therefore combined with the analytical framework of tourism geography, the dynamic process, development stages and the evolvement of the spatial structure are explored in this paper by using analytical methods of urban geography based on a case study of Sichuan province, which is rich in tourism resources in Southwest China. Findings of primary city distribution and rank-size distribution suggest that the spatial pattern of tourism cities in Sichuan province takes on a typical core-periphery structure. Chengdu, capital of Sichuan province and the biggest tourism city, is the primary tourism city and is therefore being the core city while others are peripheries of the tourism industry. Moreover, the dynamic evolvement of the spatial pattern in Sichuan belongs to the spatial polarization stage. Transportation, resource endowment, economic development, location and spatial position, urban size, function and urbanization are the important factors related to this core-periphery structure by correlation analysis. Finally, sub-core tourism cities, i.e. the second core cities such as Leshan, Aba and Mianyang can be discovered by cluster analysis. Nevertheless, these sub-core tourism cities have a long way to go in terms of the tourism industry.",
        "keywords": [
            "Core-periphery theory",
            "Sichuan province",
            "Spatial dynamic process",
            "Spatial structural form"
        ],
        "authors": [
            {
                "name": "Chunyun Shi",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Haimei You",
                "org": "Xuzhou Normal University(Xuzhou Normal University),Xuzhou,China"
            },
            {
                "name": "Donghe Li",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Yan Wang",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            }
        ],
        "venue": "Acta Geographica Sinica",
        "year": 2007
    },
    "IT7UWfKA": {
        "id": "IT7UWfKA",
        "title": "Study on the Perceived Landscape Image in the Ancient Water Towns Based on the Public Medium",
        "abstract": "Based on Lynch's theory of the city image,a modified index system of the perceived landscape image elements in ancient water towns has been established,which reflects the characteristics of ancient water towns.By counting and analyzing the frequency of the landscape image elements appearing in 993 photographs collected from ten books and six websites of the ancient water towns,some interes-ting results have been obtained.According to the results,the main perceived elements of water towns are paths and nodes,the second perceived elements are landmarks,and the images of districts and edges are weak. Among the image of nodes,the residences,the cross of ri-vers and water alleys,bridges and docks are playing a leading role;among the image of paths,tourists pay more attention to the waterway and the streets along the river;among the image of landmarks,boats and trees are the most important elements;among water edges,balusters and banks are the mainly perceived elements.Thus it can be seen that tourists' perception on ancient water towns is in relation to the water environment.Affected by the landform of ancient water towns and the time tourists spend in ancient water towns,tourists perception on area is weak.Furthermore,tourists' perception on residences is divided into two lays-the macroscopical lay and the microcosmic lay.The macroscopical lay consists of residences,houses of famous persons and mansions,while the microcosmic lay is composed of doors and windows,lanterns,carvings,courtyards,cloisters,couplets hung on the columns of a wall,dooryards,roofs,wells,alleys of a house,cliffs,stairs,gallop buildings,among which tourists pay more attention to doors and windows,lanterns and carvings.",
        "keywords": [
            "elements of image",
            "ancient water towns",
            "public medium",
            "perceived",
            "landscape"
        ],
        "authors": [
            {
                "name": "Wang Yan",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing,Jiangsu,,China"
            },
            {
                "name": "Zhang Jie",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing,Jiangsu,,China"
            },
            {
                "name": "Shi Chunyun",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing,Jiangsu,,China"
            },
            {
                "name": "Ran Jiang",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing,Jiangsu,,China"
            }
        ],
        "venue": "Journal of Beijing International Studies University",
        "year": 2007
    },
    "jw0IGnfL": {
        "id": "jw0IGnfL",
        "title": "Zipf Structure and Difference Degree Study of Tourist Flow Size System——Taking Sichuan Province as the Empirical Study Area",
        "abstract": "Grading structure of inbound tourist flow size in Sichuan Province was comparatively analysed through the Zipf theory,equilibrium degree and difference index,according to statistic data of inbound tourist flow in 1996-2004.We decided whether or not that grading structure of tourist flow size is in conformity with Zipf theory from supposition to discussion.Equilibrium degree and difference index are calculated according to information entropy principle.The result showed that Zipf,equilibrium degree and difference index may all be used to analyse the grading structure of tourist flow size,each of which has superiority and can not replace each other.Grading structure of Tourist flow size could be sectioned by Zipf parameter,and equilibrium degree and difference index can only show the difference of structure but can't clearly distinguish the point of intersect.Zipf parameter may be used to analyse the space distribution shape of the tourist flow size structure in each scaling section,but any other indexes can't.The internal structure of ineffective scaling section with unobvious Zipf feature only can be analysed through equilibrium degree and difference index.Because the two indexes neither show the scaling section separation feature nor the space distribution shape of tourist flow size structure,they only make up a deficiency to Zipf parameter while can't replace it.The study showed that the result of effective scaling section being analyzed by Zipf index,ineffective scaling section by equilibrium degree and difference index accord with objective reality and it also clearly refects the structure scaling section feature,the internal structural difference of each section and and the changing law of the total structure system.This is very important to enrich the methods of analyzing tourist flow size grading structure.Concerning the tourist flow size structure in Sichuan province,the Zipf indexes \"q\" of inbound tourist flows of all years except 1999 are over one,which are relatively steady and their tourist flow size structures appear an irregular distribution Pareto pattern.",
        "keywords": [
            "equilibrium degree",
            "difference degree",
            "tourist flow size structure",
            "Sichuan province",
            "Zipf index"
        ],
        "authors": [
            {
                "name": "Yang Guo-Liang",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing,,China;Urban-rural Planning and Landscape Design Institute,Sichuan Normal University,Chengdu,,China;College of Geography and Resources Science,Sichuan Normal University,Chengdu,,China"
            },
            {
                "name": "Zhang Jie",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing,,China"
            },
            {
                "name": "Liu Bo",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing,,China;Zhenjiang Urban Planning Department,Zhenjiang,,China"
            }
        ],
        "venue": "Journal of Nanjing University(Natural Sciences)",
        "year": 2007
    },
    "aM3MoVMl": {
        "id": "aM3MoVMl",
        "title": "Model of Protection and Tourism Development of Chinese World Heritage Based on Ecological View",
        "abstract": "From the perspective of ecological view,the relationship between protection and tourism development of chinese world heritage was analyzed.At present,there were two models of protection and tourism development of chinese world heritage: development model of man-made nature and development model of ecological nature,however,development model of man-made nature was leading.This paper also pointed out that development model of ecological nature was one best way and developmental direction of protection and tourism development of chinese world heritage on the guidance of ecological view.",
        "keywords": [
            "ecological view",
            "chinese world heritage",
            "protection and development"
        ],
        "authors": [
            {
                "name": "YANG Xiao-zhong",
                "org": "Department of Urban and Resources Sciences,Nanjing University,Nanjing ,China;College of National Territorial Resource and Tourism,Anhui Normal University,Wuhu ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Urban and Resources Sciences,Nanjing University,Nanjing ,China"
            }
        ],
        "venue": "Resource Development & Market",
        "year": 2007
    },
    "TKRaC3Ul": {
        "id": "TKRaC3Ul",
        "title": "Acid etching process for fabrication of Bi<Subscript>2</Subscript>Sr<Subscript>2</Subscript>CaCu<Subscript>2</Subscript>O<Subscript>8+<Emphasis Type=\"Italic\">x</Emphasis></Subscript> stack",
        "abstract": "We adopted a new method, acid etching process, to fabricate the intrinsic Josephson junctions based on the Bi2Sr2CaCu2O8+x\n  single crystals. By soaking the crystals into the dilute hydrochloric acid, we fabricated a junction stack successfully,\n and meantime made the surrounding area insulated. A certain concentration of hydrochloric acid was used to maintain the roughness\n of the modified layer. The current-voltage characteristic was achieved through the four terminal measurement. We could control\n the junctions’ number by changing the concentration and the soaking time. We also found that the thickness of the stack was\n equal to the average height of the insulation layer. Such a simple, convenient and controllable fabrication method with a\n high yield might widen the applications of the intrinsic Josephson junctions.",
        "keywords": [
            "acid etching process",
            " intrinsic Josephson junction",
            " concentration",
            " four-terminal measurement"
        ],
        "authors": [
            {
                "name": "Zhang Jie ",
                "org": "Research Institute of Superconductor Electronics,Nanjing University,Nanjing,China"
            },
            {
                "name": "Chen Jian ",
                "org": "Research Institute of Superconductor Electronics,Nanjing University,Nanjing,China"
            },
            {
                "name": "Wu JingBo ",
                "org": "Research Institute of Superconductor Electronics,Nanjing University,Nanjing,China"
            },
            {
                "name": "Kang Lin ",
                "org": "Research Institute of Superconductor Electronics,Nanjing University,Nanjing,China"
            },
            {
                "name": "Xu WeiWei ",
                "org": "Research Institute of Superconductor Electronics,Nanjing University,Nanjing,China"
            },
            {
                "name": "Wu PeiHeng ",
                "org": "Research Institute of Superconductor Electronics,Nanjing University,Nanjing,China"
            }
        ],
        "venue": "Chinese Science Bulletin",
        "year": 2007
    },
    "SevMOjEa": {
        "id": "SevMOjEa",
        "title": "Acid etching process for fabrication of Bi2Sr 2CaCu2O8+x stack",
        "abstract": "We adopted a new method, acid etching process, to fabricate the intrinsic Josephson junctions based on the Bi2Sr2CaCu 2O8+x single crystals. By soaking the crystals into the dilute hydrochloric acid, we fabricated a junction stack successfully, and meantime made the surrounding area insulated. A certain concentration of hydrochloric acid was used to maintain the roughness of the modified layer. The current-voltage characteristic was achieved through the four terminal measurement. We could control the junctions' number by changing the concentration and the soaking time. We also found that the thickness of the stack was equal to the average height of the insulation layer. Such a simple, convenient and controllable fabrication method with a high yield might widen the applications of the intrinsic Josephson junctions. © 2007 Science in China Press.",
        "keywords": [
            "Acid etching process",
            "Concentration",
            "Four-terminal measurement",
            "Intrinsic Josephson junction"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Jian Chen",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Jingbo Wu",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Lin Kang",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Weiwei Xu",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Peiheng Wu",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            }
        ],
        "venue": "Chinese Science Bulletin",
        "year": 2007
    },
    "VagadqIy": {
        "id": "VagadqIy",
        "title": "A Recapitulative Review of International Geomorphology",
        "abstract": "There have been 1479 articles published by geomorphology since 1987,which indicated a very complex tendency of international geomorphology study.Based on 10 themes to classify these articles uniquely,it open out primarily that the themes of space structure of the earth's surface,surface processes and environmental impact of geological disaster play more important roles than the else do,and these topics always keep in a close touch with factual cases especially,as a whole those thematic situation are also in main range of the geomorphology subject.At the same time,it is obvious to find out that new change of the geomorphology studies have occurred in the past years,which paid much attention to the modern methodology,such as outstanding techniques of information detecting or testing,and the decreasing techniques of tradition means comparatively.",
        "keywords": [
            "developing tendency",
            "topic study",
            "information technique",
            "international geomorphology",
            "surface process"
        ],
        "authors": [
            {
                "name": "QIN Zhong",
                "org": "College of Resources and Environment Engineering,Guizhou University,Guiyang ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "College of Geography and Ocean Sciences,Nanjing University,Nanjing ,China"
            }
        ],
        "venue": "Journal of Guizhou University of Technology(Natural Science Edition)",
        "year": 2007
    },
    "aCuEbii2": {
        "id": "aCuEbii2",
        "title": "Research on the Behavior Characteristics of City Leisure Resident in Hankou Recreational Waterfront",
        "abstract": "Based on the investigation data in Hankou recreational waterfront,this paper firstly presents the general features of city leisure resident.Through basic statistical analysis and cross tabulation analysis,the paper summarizes the behavior characteristics and the space preference of leisure resident in Hankou recreational waterfront.The author hopes this will be helpful to the planning of city public leisure space.",
        "keywords": [
            "Hankou",
            "leisure resident",
            "urban waterfront",
            "behavior characteristic"
        ],
        "authors": [
            {
                "name": "Liang Yuelin",
                "org": "Department of Urban and Resources Sciences,Nanjing University,Nanjing,Jiangsu,;College of Management,China University of Geosciences,Wuhan,Hubei,"
            },
            {
                "name": "Zhang Jie",
                "org": "Department of Urban and Resources Sciences,Nanjing University,Nanjing,Jiangsu,"
            }
        ],
        "venue": "Journal of Beijing International Studies University",
        "year": 2007
    },
    "5FtitKSe": {
        "id": "5FtitKSe",
        "title": "Progress and Implication in Domestic Research on Ecological Footprint Model",
        "abstract": "Ecological footprint(EF)model is an important and effective way to measure sustainability.\"EF\" model has been introduced to China from 2000 year,since then,the domestic research on ecological footprint model has been carried on and made some progress.Today,domestic study on the ecological footprint model mainly focus in three research fields,these are ecological footprint model appraisement,ecological footprints associated with different regions and special industries.Based on the review in details the latest domestic achievements and frontiers of overseas study,this paper thinks that the further research work of ecological footprint model should strengthen in four aspects at least: one is calculation ecological footprint time series,to explore the law between the ecological footprint and sustainable development;two is to compare ecological footprint of different dimension regions;three is to broaden the application in environment,social and economic fields;four is to modify and improve the ecological footprint model in China research.",
        "keywords": [
            "circulative economy",
            "sustainable development",
            "ecological footprint",
            "ecologically unequal exchange",
            "ecological rucksack"
        ],
        "authors": [
            {
                "name": "ZHANG Jin-he",
                "org": "College of National Territorial Resources and Tourism,Anhui Normal University,Wuhu ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Urban and Resources Science,Nanjing University,Nanjing ,China"
            }
        ],
        "venue": "Areal Research and Development",
        "year": 2007
    },
    "bh3nIRLo": {
        "id": "bh3nIRLo",
        "title": "Study of the Resident Perception and Attitudes in Destination from Individual Perspective——A Case Study on Jiuzhaigou",
        "abstract": "Research on resident attitudes in destination has been one of the key issues of Tourism Sociology and Tourism Geography abroad. Relevant literatures have been generally focused on community studies.They assess resident reaction to tourism at the local level and using the overall level of agreement as a measure of support for the industry.However,studies from individual perspective are rare till now.Based on the case study of Jiuzhaigou,we first divide residents into four clusters,i.e.rational,unilateral,somewhat irritated and enthusiastic supporters,according to their opinions to tourism impact and attitudes by cluster analysis and discriminant analysis,and then we search for variation at the individual level of respondents and assess the effect of socio-demographic attributes of the individual by variance analysis.Conclusion can be drawn that resident attitudes to tourism have key relations to the age,employment section and benefits from the industry.Therefore,it is of great importance for destination that residents should be encouraged to participate in tourism development.",
        "keywords": [
            "individual perspective",
            "Jiuzhaigou",
            "residents'perception and attitude"
        ],
        "authors": [
            {
                "name": "Shi Chunyun",
                "org": "College of Urban and Environmental Sciences,Xuzhou Normal University,Xuzhou ,China;School of Geographical and Oceanic Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "Zhang Jie",
                "org": "School of Geographical and Oceanic Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "Li Donghe",
                "org": "Department of Tourism Management,Anhui University, Hefei ,China"
            }
        ],
        "venue": "Journal of Beijing International Studies University",
        "year": 2007
    },
    "BXq7YtpP": {
        "id": "BXq7YtpP",
        "title": "Analysis on the spatial structure and characteristics of the eminent tourism resources in South Jiangsu - Based on GIS",
        "abstract": "This paper includes three parts. Firstly, it evaluates tourism resources of South Jiangsu based on the\"Chinese tourist resources general survey norm\". Then it analyzes the quantity and the spatial characteristics of the eminent tourism resources of south Jiangsu based on GIS. The result of comprehensive evaluation and spatial analysis showed that the humanity tourism resources play fundamental roles in the structure of the eminent tourism resources, and the natural tourism resources are important parts; and in the spatial distribution, the tourism resources show the characteristics of \"strap\" and \"circle\", and disequilibrium distribution in region. Secondly, it makes use of the graph theory to analyze the spatial structure of the eminent tourist resources and analyzes the topological properties of the tourism resources network using several indexes such as ß, γ indexes, accessibility index , average directory length and the shortest path matrix, etc. In the end, the paper pays attention to the spatial structure of tourism resources -city relations. Non-equilibrium index and geographical relation ratio are used to observe the spatial structure between the eminent tourism resources and the five cities in south Jiangsu.",
        "keywords": [
            "eminent tourism resources",
            "south jiangsu",
            "spatial characteristics",
            "spatial network structure",
            "spatial analysis",
            "geographic information systems",
            "networks",
            "matrices"
        ],
        "authors": [
            {
                "name": "Yan Wang",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Jiang Ran",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            }
        ],
        "venue": "Proceedings of SPIE - The International Society for Optical Engineering",
        "year": 2007
    },
    "as9TlLVq": {
        "id": "as9TlLVq",
        "title": "On New Zealand Tourism Research and Its Reference to China",
        "abstract": "To develop sustainable competitive advantages for destination of New Zealand and meet the needs of the tourism industry,New Zealand established three tourism research strategies successively,which were characterized by industry oriented research,stakeholders' active participation,and practical application in decision-making processes.This paper analyzes the deficiencies of tourism research of China and its causes,explores the relationship among stakeholders of tourism research,and presents some approaches to advance tourism research of China on the basis of referring to New Zealand experience,including strengthening governmental management,advancing industry oriented research,and establishing and improving the cooperation mechanism of tourism research.",
        "keywords": [
            "stakeholder",
            "tourism research strategy",
            "New Zealand"
        ],
        "authors": [
            {
                "name": "TANG Wen-yue",
                "org": "Department of Land Resources and Tourism Sciences,Nanjing University,Nanjing ;School of Tourism Management,Jiangxi University of Finance and Economics,Nanchang ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Land Resources and Tourism Sciences,Nanjing University,Nanjing "
            },
            {
                "name": "LUO Hao",
                "org": "Department of Land Resources and Tourism Sciences,Nanjing University,Nanjing "
            }
        ],
        "venue": "Geography and Geo-Information Science",
        "year": 2007
    },
    "kwNR7CJY": {
        "id": "kwNR7CJY",
        "title": "A COMPARATIVE RESEARCH ON SEASONALITY CHARACTERISTICS OF TOURIST FLOWS TO THE HISTORIC CULTURE VILLAGE(TOWN)——Examples of Xidi and Zhouzhuang",
        "abstract": "Seasonality characteristics of tourist flows to the historic culture village(town) are compared with each other,taking Xidi and Zhouzhuang as examples.According to the comparison results,they have differences in monthly imbalance of tourist flows,seasonal patterns and three seasons partition.the Gini index of Xidi and Zhouzhuang are both lower than 0.5.And the latter is lower than the former,which shows the monthly distribution of tourist flows to Zhouzhuang is relatively more balanced.The analysis of the Gini index(G) and seasonal intensity index(R) indicated that G could be a substitution for R in describing seasonal fluctuation of tourist flows.Moreover,the Gini index is better than the seasonal intensity index in some degree.As to seasonal patterns,Xidi has a tri-modal one,while Zhouzhuang exhibits a bimodal one.Three seasons partition of two sites is obtained by k-means cluster analysis.Cluster analysis result suggests regularity of seasonality of two cases and season partition of Xidi is more regular than that of Zhouzhuang. When analyzing influential factors,physiological climate suitability and public holiday are selected as two basic elements representing the natural factor and institutionalized factor respectively.As far as physiological climate suitability is concerned,the most comfortable months of Xidi are April,May and October and those of Zhouzhuang are May,September and October.But those months are not fully consistent with peak seasons of each site.So it is concluded that natural factors are not dominant ones in explaining seasonal changes of tourist flows.At the same time,peak seasons' distribution of Xidi is found to be identical with monthly distribution of public holiday.This consistency demonstrates that public holiday is a more important influential factor for Xidi when compared with natural ones. The life cycle of tourist sites is also considered to be one factor that has impact on seasonality characteristics.Currently Xidi and Zhouzhuang are experiencing the development stage.Finally,it is suggested seasonality characteristics of tourist flows could be an evaluation index for judging developing period of tourist sites.",
        "keywords": [
            "historic culture village(town)",
            "tourist flow",
            "Zhouzhuang",
            "Xidi",
            "seasonality"
        ],
        "authors": [
            {
                "name": "ZHONG Jing",
                "org": "Department of Land Resources and Tourism Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Land Resources and Tourism Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "LI Dong-he",
                "org": "Department of Land Resources and Tourism Sciences,Nanjing University,Nanjing ,China;Tourism Management Department of Anhui University,Hefei ,China"
            },
            {
                "name": "LU Song",
                "org": "Department of Land Resources and Tourism Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "ZHAO Yong",
                "org": "Department of Land Resources and Tourism Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "CHEN You-jun",
                "org": "Department of Land Resources and Tourism Sciences,Nanjing University,Nanjing ,China"
            }
        ],
        "venue": "Human Geography",
        "year": 2007
    },
    "0OrjOAnC": {
        "id": "0OrjOAnC",
        "title": "The characteristics of natural scenery sightseers' sense of place: A case study of Jiuzhaigou, Sichuan",
        "abstract": "Sense of place is an important research field of humanistic geography in man-land relationship research. Travel and sightseeing is a significant way of perceiving and understanding environments and tourist's sense of place is the outcome of interaction between tourist and destination environment. By constructing model of tourist's sense of place, a case study of Jiuzhaigou shows that (1) differences exist among four dimensions of tourist's sense of place, namely natural scenery, social cultural setting, tourism function, and affectional attachment; (2) natural scenery of Jiuzhaigou is valued unanimously by tourists, which is the primary cause of tourists' affectional attachment to Jiuzhaigou; (3) social cultural settings of Jiuzhaigou is low-valued relatively, which affects tourists' experiential evaluation of tourism environment and function; (4) tourists endow Jiuzhaigou with more meanings of natural scenery sightseeing and aesthetic value than meanings of folk-custom culture experience and historical value, the place particularity of \"Tibetan village\" is not identified enough by tourists; and (5) significant differences of perception and experiential evaluation occur in Tibetan social customs, local culture, tourism service, sightseeing order and atmosphere. Its implication in planning and management of natural resources and tourist destination is also discussed.",
        "keywords": [
            "Jiuzhaigou",
            "Natural scenery sightseeing place",
            "Sense of place",
            "Tourist"
        ],
        "authors": [
            {
                "name": "Wenyue Tang",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Hao Luo",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Xiaozhong Yang",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Donghe Li",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            }
        ],
        "venue": "Acta Geographica Sinica",
        "year": 2007
    },
    "1ERBAsTR": {
        "id": "1ERBAsTR",
        "title": "Zipf Structure Development of Tourist Flow Based on the Distribution of Scenic Spots of Sichuan Province",
        "abstract": "Firstly,the paper analyzes the characters of the distribution of scenic spot system,and concludes that the spatial expansion of scenic spot system is not an ordinary balanced expansion,but an expansion of self-similarity with a fractal character of its spatial distribution.Based on the Zipf principle,the paper analyzes the structure of \\!Rank-Scale\\\" distribution restricted by the distribution of scenic spot system,and shows that the regional scale distribution of tourist flow is obeyed to the Zipf principle and its evolvement experiences the process of partial fractal-single fractal-regressive partial fractal-double partial fractal with its spatial distribution structure transformed from Pareto pattern to Logistic Normal Distribution pattern.Based on the comparative analysis of the producing and developing process between the spatial fractal of scenic spot system and its Zipf structure of tourist flow,the paper concludes that both factors are influenced by each other.As a very important role,the growth and regression of the fractal of scenic spot system can promote or restrict the process of forming and developing the Zipf quantity structure of tourist flow.Both involvement process of structure has the coherent developing trend,but loss of synchronization in each involvement path is mainly decided by other factors.",
        "keywords": [
            "Zipf structure",
            "tourist flow",
            "scenic spot",
            "fractal structure"
        ],
        "authors": [
            {
                "name": "YANG Guo-liang",
                "org": "Urban-rural Planning and Landscape Design Institute of Sichuan Normal University,Chengdu ,China;Department of Land Resources and Tourism Sciences of Nanjing University,Nanjing ,China;College of Geography and Resources Science,Sichuan Normal University,Chengdu ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Land Resources and Tourism Sciences of Nanjing University,Nanjing ,China"
            },
            {
                "name": "LIU Bo",
                "org": "Department of Land Resources and Tourism Sciences of Nanjing University,Nanjing ,China;Zhen Jiang Urban Planning Department,Zhenjiang ,China"
            },
            {
                "name": "REN Xuan-yu",
                "org": "Urban-rural Planning and Landscape Design Institute of Sichuan Normal University,Chengdu ,China"
            },
            {
                "name": "WANG Rui-xia",
                "org": "Urban-rural Planning and Landscape Design Institute of Sichuan Normal University,Chengdu ,China"
            }
        ],
        "venue": "Tourism Tribune",
        "year": 2007
    },
    "L47scm0D": {
        "id": "L47scm0D",
        "title": "Study on tourists flow rank-size distribution variation and the mechanism: Taking Sichuan Province as an example",
        "abstract": "The Zipf theory is the law to study the relation between word frequency and word sequence which has been widely used in the fields of urban system,transportation net and metrology.It is also involved in tourist flow,but only used for simple analysis on the ranking of tourist flow size,without deep discussion for the spatial distribution evolution rules of size structure.This paper studied the spatial distribution changing characteristics and the mechanism of tourist flow size by Zipf Rules.It tried to find the changing law of the size distribution to guide the tourism resource development sequence,and to provide new theoretical support for spatial distribution of tourism scenic sites and urban system of tourist nodes.Compared with traditional quantitative method,Zipf theory can be used to judge the non-scaling section of tourist flow size distribution more precisely,and to interpret the varying characteristic of tourist size distribution based on non-scaling section and Zipf parameters.This will provide new quantitative method for the study on the spatial distribution variation of tourist flow.In this paper,Sichuan Province is taken as the study area.From size distribution analysis of domestic and inbound tourist flow during 1996-2005,it proves that the size distribution structure satisfies Zipf law in each year.Based on this result,this paper further analyzed the variation law of non-scaling range,non-scaling section characteristic and internal structure of each non-scaling range on tourist flow rank-size ln-ln graph.The conclusion shows that non-scaling range for both domestic and inbound tourist flow vary identically on ln-ln graph,with a gradually expanding tendency.However,the variation of spatial fractal structure and distribution pattern is not synchronous.From spatial fractal structure,domestic tourist flow size distribution varies from local fractal in 1997 to single fractal of 1998-2003,then to local fractal in 2004 and finally double fractal in 2005,while inbound tourist flow varies from local fractal in 1998 to single fractal in 1999 and till now,without double fractal.The spatial distribution variation also shows the difference: domestic tourist flow is changing from Pareto distribution pattern to lognormal distribution,but spatial distribution of inbound tourist flow is still steady as Pareto pattern.Perhaps the main reason is that the transportation improvement and new scenic sites development has more effect on destination choice of domestic tourists than on that of inbound tourists.This leads to the more apparent distribution variation of domestic tourist flow size structure.",
        "keywords": [
            "non-scaling section",
            "tourist flow",
            "Zipf theory",
            "rank-size distribution",
            "Sichuan Province"
        ],
        "authors": [
            {
                "name": "YANG Guo-liang",
                "org": "The Department of Land Resources and Tourism Sciences,Nanjing University,Nanjing ,China;Urban-rural Planning and Landscape Design Institute,Sichuan Normal University,,China;College of Geography and Resources Science,Sichuan Normal University,Chengdu ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "The Department of Land Resources and Tourism Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "LIU Bo",
                "org": "Zhenjiang Urban Planning Department,Zhenjiang ,China"
            },
            {
                "name": "LI Min",
                "org": "Urban-rural Planning and Landscape Design Institute,Sichuan Normal University,,China"
            },
            {
                "name": "WAN Quanyou",
                "org": "Urban-rural Planning and Landscape Design Institute,Sichuan Normal University,,China"
            }
        ],
        "venue": "Geographical Research",
        "year": 2007
    },
    "Hjzgf6Oe": {
        "id": "Hjzgf6Oe",
        "title": "Space structure and tourist economic interrelationships of the tourism system——taking Sichuan Province as an example",
        "abstract": "The spatial distribution of tourist cities and spots in Sichuan Province possess local fractional properties.This paper,taking the year 2004 as an example,confirmed the existence of the spatial fractional features of tourism system in Sichuan Province by analyzing whether urban tourist flow order-scale structure can satisfy the law of Zipf.It also analyzed the strength and direction of tourist economic links inside the tourism system of Sichuan Province by the gravity model,and concluded that the tourist economic links mainly exist in a few cities,among which the effect and position of Chengdu is especially prominent, whose tourist economic relationship quantity accounts for 32.2% of the whole province.Chengdu is the strong center for tourist economic links,and forms two concentric circles outwards.One includes Deyang,Mianyang, Leshan,Meishan and Ziyang,and forms the core circle of tourism in Sichuan Province;the other includes Suining,Nanchong,Guang'an,Neijiang,Zigong,Luzhou,Yibin,Ya'an,and Maerkang.All the cities have strong tourist economic links with Chengdu.",
        "keywords": [
            "tourism city",
            "tourist economic links",
            "tourism spot",
            "spatial fractional",
            "Sichuan Province"
        ],
        "authors": [
            {
                "name": "YANG Guo-liang",
                "org": "Department of Land Resources and Tourism Sciences,Nanjing University,Nanjing ,China;Urban-rural Planning and Landscape Design Institute,Sichuan Normal University,Chengdu ,China;College of Geography and Resources Science,Sichuan Normal University,Chengdu ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Land Resources and Tourism Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "AI Nan-shan",
                "org": "College of Architesture and Environment,Sichuan University,Chengdu ,China"
            },
            {
                "name": "LIU Bo",
                "org": "Department of Land Resources and Tourism Sciences,Nanjing University,Nanjing ,China;Zhenjiang Urban Planning Department,Zhenjiang ,Jiangsu,China"
            },
            {
                "name": "WANG Rui-xia",
                "org": "Urban-rural Planning and Landscape Design Institute,Sichuan Normal University,Chengdu ,China"
            }
        ],
        "venue": "Journal of Lanzhou University(Natural Sciences)",
        "year": 2007
    },
    "wKAcAEIs": {
        "id": "wKAcAEIs",
        "title": "A Study on Tourism Image Positioning of Ancient Water Towns in Suzhou City——Take Some Ancient Water Towns as Examples",
        "abstract": "Ancient towns tourism is a favorite product in modern tourists market.Suzhou City is abundant of ancient water towns with various characteristics,therefore,found a favorable resources foundation for the tourism development in these towns.However,due to the homogeneity in tourism product in ancient water towns,strong competitions between them are inevitable.Tourism resort image strategy is one of the important strategies for boosting the sustainable tourism development in ancient water towns in Suzhou City.Based on the tourism resort image slogans of ancient water towns,a comparative study on image positioning of ancient water towns in Suzhou City is conducted.Also,some principles and suggestions for the image positioning of ancient water towns in Suzhou City are proposed.The main objective of this paper is to promote the harmonious and sustainable tourism development of ancient water towns in Suzhou City.",
        "keywords": [
            "tourist resort image",
            "ancient water towns",
            "Suzhou City",
            "positioning"
        ],
        "authors": [
            {
                "name": "LI Dong-he",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,China;Department of Tourism Management,Anhui University,Hefei ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "LU Song",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "ZHONG Jing",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,China"
            }
        ],
        "venue": "Areal Research and Development",
        "year": 2007
    },
    "8uQBTFKD": {
        "id": "8uQBTFKD",
        "title": "Comparison of resort residents' perceptions and attitudes: Case studies in Xidi Village and Jiuzhaigou",
        "abstract": "Studies on the residents' perceptions and attitudes toward tourism destinations have been a lasting study topic of tourism geography. A comparative study of different resort residents' perceptions and attitudes is one of the future study subjects. The paper analyzes the difference of residents' perceptions and attitudes in Xidi and Jiuzhaigou. The results are drawn as follows: (1) Residents in Xidi and Jiuzhaigou all have positive perceptions and attitudes toward the tourism impacts in the host community. But residents in Jiuzhaigou have more positive support to the tourism development than those in Xidi, and they have much more tourism income than those in Xidi. (2) Residents in Jiuzhaigou have more tourism economic profit, socio-cultural impact and environmental impact perceptions than those in Xidi. At the same time, they have also more tourism economic cost perceptions. 3) From the residents' characteristics, the paper identified correlation factors and predictors of residents' attitudes toward tourism development in Xidi Village and Jiuzhaigou resort by correlation and regression analysis. There are different community characteristics in different types of tourism destinations. The findings indicate that these communities with different characteristics, such as resort characteristics, dependence on the tourism industry, economic development level, territorial structure, heritage protection and tourism management mechanism and host-gest cultural difference, should have different residents' perceptions and attitudes toward tourism impacts. Based on social exchange theory, because of capital proceeds and compensation of being disturbed, residents have more profit expectations. Then this brings out that their realistic profit is lower than their expected profit. So compared with their counterparts in Jiuzhaigou, residents in Xidi tend to underestimate tourism economic profit and social profit, and overestimate social cost.",
        "keywords": [
            "Comparative study",
            "Jiuzhaigou",
            "Residents' perceptions",
            "Tourism impact",
            "Xidi"
        ],
        "authors": [
            {
                "name": "Song Lu",
                "org": "Anhui Normal University(Anhui Normal University),Wuhu,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Donghe Li",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Xiaozhong Yang",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Wenyue Tang",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            }
        ],
        "venue": "Acta Geographica Sinica",
        "year": 2008
    },
    "ZhjQOyzb": {
        "id": "ZhjQOyzb",
        "title": "Length of Stay Characteristics and Its Influences of Urban Plaza Users——Taking Taihu Lake Plaza,Wuxi City as an Example",
        "abstract": "The users' length of stay was one of important aspects of the urban plaza public using attributes.However,there were few case studies about it.This article examined the characteristics of users'stay and its influence factors with case survey of Taihu Lake Plaza,Wuxi City.The findings indicated that,the users' length of stay was influenced greatly by the travel time and travel purposes but very little by the basic characteristics,travel time ratio was a key constraint to the changes of the average length of stay accompanied by travel time,with the travel time ratio decreasing,percents of the users increase,most of the ratio were less than 1∶2.",
        "keywords": [
            "urban plaza",
            "travel time",
            "travel time ratio",
            "length of stay"
        ],
        "authors": [
            {
                "name": "TIAN Zhun-jun",
                "org": "Shool of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Shool of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "CAO Jing",
                "org": "Shool of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "LIU Chuan-hua",
                "org": "Shool of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,China"
            }
        ],
        "venue": "Resource Development & Market",
        "year": 2008
    },
    "NCVDPLcL": {
        "id": "NCVDPLcL",
        "title": "THE EVALUATION ON THE VISUAL SATISFACTION OF ENVIRONMENTAL SPACE OF URBAN SCULPTURE——TAKING THREE ENVIRONMENTAL SPACE OF URBAN SCULPTURE IN NANJING AS AN EXAMPLE",
        "abstract": "Using the methods of Semantic Differential Method and Factor Analysis, and taking three environmental space of urban sculpture in Nanjing city as an example, we quantitatively evaluated the urban dwellers' subjective impressions of the different types of environmental space of urban sculpture. The result shows that the feelings of psychological environment of the target audience and the effects of landscape of the environmental space account for a very large component in the quantitative evaluation of the visual satisfaction of environmental space of urban sculpture.",
        "keywords": [
            "urban sculpture",
            "Semantic Differential Method",
            "visual satisfaction",
            "environmental space"
        ],
        "authors": [
            {
                "name": "JIANG Zhou",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,Jiangsu,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,Jiangsu,China"
            },
            {
                "name": "QI Qiu-yin",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,Jiangsu,China"
            }
        ],
        "venue": "Economic Geography",
        "year": 2008
    },
    "jvZYUZH6": {
        "id": "jvZYUZH6",
        "title": "Spatial Discrepancy of Urban Leisure Industry",
        "abstract": "City is a spatial concentration of a wide variety of leisure facilities as well as an important leisure space of urban residents and tourists.Although some researchers have done much on the study of the urban leisure space,most of their work had been undertaken qualitatively.This paper explores a quantitative approach to analyze the urban leisure space by using leisure Index,diversity index,dominance index and evenness index.Based on the fieldwork and quantitative analysis on the 1192 industries of 12 urban districts in Zhenjiang city,the leisure functions and the dominant leisure industries and their spatial discrepancy of different urban districts and the spatial distribution laws of different leisure industries in urban districts are analyzed.The results are as follows: ① The leisure index implies that leisure is the most important function of the city and its structure accounts for the distribution laws of the different leisure industries.② The diversity index indicates that different urban districts have different leisure function.Moreover the dominance index furthers to explain the key leisure industries in each district.③ The evenness index illustrates that the trade-leisure spots have the most ubiquitous distribution,while the sightseeing spots are characterized with resource-oriented.Instead of confining to conceptual description and investigation mode,which has mainly focused on the recreational business district,this paper goes beyond that and extends the leisure study to a normal urban context.The quantitative approach and the final results would be of great value to the planner and manager of the urban leisure space,as well as the policy-maker of the city.",
        "keywords": [
            "urban leisure space",
            "spatial discrepancy",
            "diversity index",
            "leisure index",
            "evenness index",
            "dominance index"
        ],
        "authors": [
            {
                "name": "SHI Chun-yun",
                "org": "College of Urban and Environmental Sciences,Xuzhou Normal University,Xuzhou Jiangsu ,China;School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing Jiangsu ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing Jiangsu ,China"
            },
            {
                "name": "LI Ya-bing",
                "org": "School of International Economics & Management,Lanzhou University of Technology,Lanzhou Gansu ,China"
            },
            {
                "name": "ZHANG Hong-lei",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing Jiangsu ,China"
            },
            {
                "name": "YOU Hai-mei",
                "org": "College of Urban and Environmental Sciences,Xuzhou Normal University,Xuzhou Jiangsu ,China"
            }
        ],
        "venue": "China Population Resources and Environment",
        "year": 2008
    },
    "TefRFNsP": {
        "id": "TefRFNsP",
        "title": "The Leisure Consumption Psychology and Behavior of Female College Students",
        "abstract": "By meaus of questionarre and interview,the paper makes a sample of the female students at Weihai College,Shangdong University,about their leisure consumption psychology and beharvior.The result shows that such consumption is usually rational for both substantial and fashionable purposes.It is intended to lead the trend of rational consumption and also offer some referemes for business marketing.",
        "keywords": [
            "psychology consumption",
            "consumption behavior",
            "female college students",
            "leisure"
        ],
        "authors": [
            {
                "name": "LI Hui",
                "org": "School of Business Studies,Weihai College Shandong University,Weihai ,China"
            },
            {
                "name": "WU Wen-xin",
                "org": "Institute of Leisure Studies,Weihai College Shandong University,Weihai ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "School of Geography and Marine Science,Nanjing University,Nanjing ,China"
            }
        ],
        "venue": "Commercial Research",
        "year": 2008
    },
    "kIHYIpSO": {
        "id": "kIHYIpSO",
        "title": "Unprecedented immunosuppressive polyketides from Daldinia eschscholzii, a mantis-associated fungus",
        "abstract": "(Figure Presented) Going with a gut reaction: Dalesconols A (structure shown) and B were discovered in the title fungus (middle picture) derived from the mantis gut. The novel architecture and biological profiles of these natural products make the dalesconols attractive lead compounds for the development of immunosuppressive agents. © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.",
        "keywords": [
            "biosynthesis",
            "immunosuppressants",
            "natural products",
            "polyketides",
            "structure elucidation"
        ],
        "authors": [
            {
                "name": "Ying Lao Zhang",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Hui Ming Ge",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Wei Zhao",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Hao Dong",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Qiang Xu",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Shu Hua Li",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Jing Li",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Yong Chun Song",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Ren Xiang Tan",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            }
        ],
        "venue": "Angewandte Chemie (International ed. in English)",
        "year": 2008
    },
    "KO8vx7US": {
        "id": "KO8vx7US",
        "title": "Tourism Destination Image Characteristics and It′s Management",
        "abstract": "Tourism destination image plays an important and significant role in the development of tourism industry.In the current study of the tourism destination image,the analysis on characteristics and the management of the tourism destination image is weak.The content of tourism destination image includes the systematic tourism destination image design,the planning management,the tourism destination image marketing management and the tourism destination image monitoring management.Some specific strategies are needed for implementing the tourism destination image management to construct the frame.",
        "keywords": [
            "tourism destination image management",
            "tourism destination image",
            "characteristic"
        ],
        "authors": [
            {
                "name": "WU Tie-hong",
                "org": "Department of Land Resources and Tourism Science,Nanjing University,Nanjing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Land Resources and Tourism Science,Nanjing University,Nanjing ,China"
            },
            {
                "name": "ZHANG Hong-lei",
                "org": "Department of Land Resources and Tourism Science,Nanjing University,Nanjing ,China"
            }
        ],
        "venue": "Journal of Inner Mongolia University(Philosophy and Social Sciences)",
        "year": 2008
    },
    "RLMukRwY": {
        "id": "RLMukRwY",
        "title": "Structural Equation Model for tourism destination competitiveness from tourists' perception perspectives",
        "abstract": "Previous work of tourism competitiveness has focused more on integrative destinations, such as nations, states (provinces), cities, or destinations having similar attractions. However, appropriate research perspectives and methods havenot been found for evaluating tourism destinations of different types and different sizes.Moreover, early work of Structural Equation Model applied to tourism science has generally limited to a given destination and has rarely compared among different tourism destinations. Therefore, the main thrust of the paper will be concerned with comparing the tourism competitiveness between Jiuzhaigou and Lushan from tourists' perception perspective by applying structural equation model. Based on the Confirmatory Factor Analysis, Cross-validation, and Invariance Measurement, the theoretical model has stability and validity between different samples. Jiuzhaigou has more advantages than Lushan by comparing tourist perception in resources, community attitudes, integral satisfaction and loyalty except service through the Mean Model of Structural Equation. Structural Equation Models, especially Mean structural Model, are applied to and validated in this study, which is a step forward toward the quantitive research methods of destination competitiveness. It is the first time that latent variable of community attitudes has been introduced into the tourist perception model, which is testified to be positively correlated with the tourists' satisfaction and loyalty.",
        "keywords": [
            "tourists' perception perspective",
            "Jiuzhaigou",
            "Mean Structural Model",
            "tourism destination competitiveness",
            "Lushan",
            "Structural Equation Model"
        ],
        "authors": [
            {
                "name": "SHI Chun-yun",
                "org": " College of Urban and Environmental Sciences, Xuzhou Normal University, Xuzhou , China"
            },
            {
                "name": "ZHANG Jie",
                "org": " School of Geographic and Oceanographic Sciences, Nanjing University, Nanjing , China"
            },
            {
                "name": "YOU Hai-mei",
                "org": " College of Urban and Environmental Sciences, Xuzhou Normal University, Xuzhou , China"
            }
        ],
        "venue": "Geographical Research",
        "year": 2008
    },
    "H3meRkSm": {
        "id": "H3meRkSm",
        "title": "A Study on Tourists' Traveling Experience in Tourist Destinations and Revisit Intention——A Case Study of Yixing",
        "abstract": "Tourists' revisit plays an important role for the sustainable development of mature tourist destinations.Based on retrospect of related study about revisit both at home and abroad,the paper studies the phenomenon of revisit from microscopic tourists' behavior.After comparing the differences of the experiences of first-time visitors and repeat visitors in Yixing,the authors find that there are significant differences in ages,occupation,traveling costs,duration of stay,motivation and traveling barrier.While comparing the effect of different binary response models on revisit intention and explaining the estimation result by using Logit model,the paper holds the view that satisfaction of cicerones,duration of stay and means of transportation exert significant influence on revisit intention and calculate the ratio of different influencing factors.Finally,based on the above study results,the authors offer some suggestions about the development of tourism market in Yixing.",
        "keywords": [
            "Logit model",
            "Yixing",
            "revisit"
        ],
        "authors": [
            {
                "name": "YANG Yang",
                "org": "School of Hotel and Tourism Management,the Hong Kong Polytechnic University,Kowloon,Hong Kong SAR,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Land Resource and Tourism,Nanjing University,Nanjing ,China"
            },
            {
                "name": "ZHAO Ning-xi",
                "org": "Department of Land Resource and Tourism,Nanjing University,Nanjing ,China"
            }
        ],
        "venue": "Tourism Tribune",
        "year": 2008
    },
    "JeE3drcD": {
        "id": "JeE3drcD",
        "title": "Review of Application Research on Structural Equation Model to Tourism Science",
        "abstract": "Literature of structural equation model application to tourism research was reviewed by surfing the international famous journals in tourism field and journals in CNKI.Based on the introduction of principles and main strengths of structural equation model,the application research on SEM to tourism was analyzed from tourists'perception and behavior,residents'perception and attitude to tourism development,employee perspectives respectively.Then general process and criterion of application research were induced.Finally,it was concluded that the application research of SEM to tourism in China was relatively rare.Resident and employee should be placed more attention to and spatial and temporal study should be compared and validated in the future.",
        "keywords": [
            "tourist",
            "tourism research",
            "structural equation model(SEM)",
            "resident"
        ],
        "authors": [
            {
                "name": "SHI Chun-yun",
                "org": "College of Urban and Environmental Sciences,Xuzhou Normal University,Xuzhou ,China;School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "ZHANG Hong-lei",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "YANG Yang",
                "org": "Center for Recreation and Tourism Research,Beijing University,Beijing ,China"
            }
        ],
        "venue": "Resource Development & Market",
        "year": 2008
    },
    "hNugJDzo": {
        "id": "hNugJDzo",
        "title": "An Empirical Study on Tourism Bubble——A Case Study of Jiuzhaigou,Sichuan Province",
        "abstract": "Tourism bubble is an objective phenomenon in the development of tourism and will have far-reaching impact on tourists' experiences and tourist destinations. The paper, based on the theoretical study of tourism bubble, taking Jiuzhaigou, Sichuan Province as an example, makes an empirical study of tourism bubble in the hope of pushing forward its domestic study. The paper analyzes tourists' bubble in Jinzhaigou, tourism industry bubble and the cause of formation of bubble in tourist destinations. The study indicates that the phenomenon of tourism bubble does exist in Jiuzhaigou tourist area and has brought about influence on tourists' experiences and social-culture in destinations. This study will further promote our understanding of tourism bubble so as to offer references for formulating the strategies of the development of tourism industry in both Jiuzhaigou and other tourist destinations.",
        "keywords": [
            "tourism bubble",
            "tourism impact",
            "Jiuzhaigou",
            "tourists' experience"
        ],
        "authors": [
            {
                "name": "LI Dong-he",
                "org": " Department of Tourism Management,Anhui University, Hefei ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": " School of Geographic and Oceanographic Sciences,Nanjing University, Nanjing ,China"
            },
            {
                "name": "YANG Xiao-zhong",
                "org": " School of Geographic and Oceanographic Sciences,Nanjing University, Nanjing ,China"
            }
        ],
        "venue": "Tourism Tribune",
        "year": 2008
    },
    "rXsLrMBd": {
        "id": "rXsLrMBd",
        "title": "Level of Tourism Participation of Community and Influencing Factors in Ancient Villages:A Comparative Research on Xidi,Hongcun and Nanping",
        "abstract": "This study attempts to build measurement index of level of community tourism participation based on the benefit from the perspective of family after setting up probable influencing factors.Taking examples of ancient villages including Xidi,Hongcun and Nanping in South Anhui,levels of tourism participation of community and their formation mechanism are analysed.The results indicate that: 1) The differences of level of tourism participation within each ancient village and between ancient villages are owing to interactive impact between family micro-factors and community middle-factors.2) According to direct path coefficient and indirect path coefficient,we find that influencing directions of family micro-factors are the same while their influencing extents are different.This is accorded with the result of questionnair so strong interpreting power and potential application value of this method are proved.and 3) the main means of improving level of tourism participation of community and weakening its spatial difference are to give benefit to residents and strengthen the ability for getting benefit,and in this course,government should play a leading role.",
        "keywords": [
            "level of participation",
            "influencing factor",
            "tourism participation of community",
            "ancient village",
            "path coefficient"
        ],
        "authors": [
            {
                "name": "YANG Xiao-Zhong",
                "org": "Department of Land Resources and Tourism Sciences,Nanjing University,Nanjing,Jiangsu ;College of Territorial Resource and Tourism,Anhui Normal University,Wuhu,Anhui "
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Land Resources and Tourism Sciences,Nanjing University,Nanjing,Jiangsu "
            },
            {
                "name": "TANG Wen-Yue",
                "org": "Department of Land Resources and Tourism Sciences,Nanjing University,Nanjing,Jiangsu "
            },
            {
                "name": "LU Song",
                "org": "Department of Land Resources and Tourism Sciences,Nanjing University,Nanjing,Jiangsu "
            }
        ],
        "venue": "Scientia Geographica Sinica",
        "year": 2008
    },
    "KCLmBwsA": {
        "id": "KCLmBwsA",
        "title": "The Foundation and Strategy of Tourism Collaboration of Nanjing,Zhenjiang and Yangzhou",
        "abstract": "By the analysis of tourism resources,district condition,transportation convenience and developed economy,we can see that three cities can realize the creation of tourism trademark,and meanwhile realize the benefit maximum of tourism development.",
        "keywords": [
            "Zhenjiang",
            "Nanjing",
            "Yangzhou",
            "district collaboration"
        ],
        "authors": [
            {
                "name": "Liu Chuanhua",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "Zhang Jie",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "Cao Jing",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "Chen Caihong",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "Zhang Honglei",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,China"
            }
        ],
        "venue": "Henan Science",
        "year": 2008
    },
    "BBkdylWr": {
        "id": "BBkdylWr",
        "title": "Application of analytic hierarchy process and fuzzy math in the evaluation of Chinese cave tourism resources",
        "abstract": "Thirty typical caves from Southwest China,Central China,North China,Southeast China and Northeast China are selected as the study object.Firstly,analytic hierarchy process(AHP) is used to establish evaluation index model.And then,structural matrix is used to determine the weight of the indicators.Finally,based on the fuzzy math decision-making theory,the grades and scores of the cave tourism resources are determined.Furthermore,2-D map of tourism resource endowment and market condition is mapped with SPSS software in order to analyze the membership intervals of cave tourism resources in different regions.The results show that tourism resource endowment and market condition of all the regionalized cave belong to the\"general\"rating above.The comprehensive evaluation results of two dimensions show that most of the cave tourism resources belong to the\"good\"and\"better\" rating,cave tourism resources in the southwest and central China belong to the highest rating,cave tourism resources in the southeast region are concentrated in\"good\"rating.And the Shihuadong,the Yunshuidong,the Kongshandong and the Xuehuadong in the north region belong to the\"good\",\"better\",\"general\",\"poor\"rating;Benxishuidong tourism resource in the northeastern region belong to \"general\"rating.",
        "keywords": [
            "tourism resource",
            "fussy math",
            "karst",
            "AHP"
        ],
        "authors": [
            {
                "name": "LIU Chuan-hua",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing,Jiangsu ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing,Jiangsu ,China"
            },
            {
                "name": "CAO Jing",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing,Jiangsu ,China"
            },
            {
                "name": "ZHANG Hong-lei",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing,Jiangsu ,China"
            },
            {
                "name": "TIAN Zhun-jun",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing,Jiangsu ,China"
            },
            {
                "name": "WANG Lan",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing,Jiangsu ,China"
            }
        ],
        "venue": "Carsologica Sinica",
        "year": 2008
    },
    "q4Brlhaf": {
        "id": "q4Brlhaf",
        "title": "Research on Model of Spatial Distribution of Tourists' Cost in Destination in Theory of Behavioral Ecology——Taking Nanjing Visitor as an Example",
        "abstract": "Choosing 3204 available swatch in the data offered by Jiangsu tourism bureau,with a series of statistical methods,the authors divided the model of spatial distribution of tourists' cost in destination into 3 steps:increasing step,stagnant step and decreasing step,and in the theory of economy of the feeding behavior,explained two steps of the model of spatial distribution,and explained the decreasing step in the view of fund limit.",
        "keywords": [
            "cost in destination",
            "spatial distribution model",
            "tour distance"
        ],
        "authors": [
            {
                "name": "CAO Jing",
                "org": "School of Geographic and Oceanographic Science,Nanjing University,Nanjing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "School of Geographic and Oceanographic Science,Nanjing University,Nanjing ,China"
            },
            {
                "name": "ZHANG Hong-lei",
                "org": "School of Geographic and Oceanographic Science,Nanjing University,Nanjing ,China"
            },
            {
                "name": "SHI Chun-yun",
                "org": "School of Geographic and Oceanographic Science,Nanjing University,Nanjing ,China"
            },
            {
                "name": "LIU Ze-hua",
                "org": "School of Geographic and Oceanographic Science,Nanjing University,Nanjing ,China"
            },
            {
                "name": "JIANG Zhi-jie",
                "org": "School of Geographic and Oceanographic Science,Nanjing University,Nanjing ,China"
            },
            {
                "name": "LIU Chuan-hua",
                "org": "School of Geographic and Oceanographic Science,Nanjing University,Nanjing ,China"
            }
        ],
        "venue": "Resource Development & Market",
        "year": 2008
    },
    "UCp7s5az": {
        "id": "UCp7s5az",
        "title": "Perceptive difference of tourism destination image along with time:A case study of Tiantangzhai scenic spot,Anhui Province",
        "abstract": "It is one of the seven main topics in the study field of the tourism destination image that the tourism destination image changes along with time.Based on the model of tourism destination formation that is a general framework of tourism destination image,this paper proposes a study method to analyze the perceptive difference of the tourism destination image along with time,evaluates the changes of pre/post tourism destination image from the overall point of view,which extends further the assessment method of tourism destination image focusing on the destination multi-dimensional attributes.The main idea of this method is to evaluate and contrast the change of cognitive,affective and overall image between pre-visit and post visit using the quantitative methods such as principal components analysis and paired sample t test.This paper applies this method to Tiantangzhai scenic spot of Anhui province and finds that the tourism destination image of Tiantangzhai scenic spot between pre-visit and post visit changes steadily to a certain degree.The overall image' assessment of Tiantangzhai scenic spot is positive either in pre-visit or in post visit without changes,which shows that the tourism destination image maintained relative stability.However,the specific perception value numbers between pre-visit and post visit have certain changes and differences,the assessment value number of the evaluation factors is decreased or increased respectively.Overall,the perception value number of pre-visit tourism destination image is larger than that of post visit,indicating a higher level of expectations of tourists to Tiantangzhai scenic spot.Managers of Tiantangzhai scenic spot should take some measures according to the situation of the perceptive differences of the tourism destination image between pre-visit and post visit,such as strengthening management and the construction of scenic areas,upgrading and improving the tourism destination image.Through the empirical study,this paper draws conclusions as follows:The empirical results achieved the expected goals,and validated that the tourism destination image has the characteristics of stability again.This method that compares the changes and the difference degree of pre/post tourism destination image from the global point of view is feasible,thus it can provide a useful reference for the follow-up studies.",
        "keywords": [
            "Tiantangzhai scenic spot",
            "tourism destination image",
            "perception",
            "change along with time"
        ],
        "authors": [
            {
                "name": "WU Tie-hong",
                "org": "Department of Land Resources and Tourism Science,Nanjing University,Nanjing ,China;Tourism Department of College Humanities,Inner Mongolia University,Huhhot ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Land Resources and Tourism Science,Nanjing University,Nanjing ,China"
            },
            {
                "name": "YANG Xiao-zhong",
                "org": "Department of Land Resources and Tourism Science,Nanjing University,Nanjing ,China"
            },
            {
                "name": "LI Wen-jie",
                "org": "College of Geographic Science,Inner Mongolia Normal University,Huhhot ,China"
            },
            {
                "name": "ZHANG Hong-lei",
                "org": "Department of Land Resources and Tourism Science,Nanjing University,Nanjing ,China"
            }
        ],
        "venue": "Geographical Research",
        "year": 2008
    },
    "q5RAhiMt": {
        "id": "q5RAhiMt",
        "title": "Measuring the ecological security of tourist destination:Methodology and a case study of Jiuzhaigou",
        "abstract": "From the security of the relationship between human and nature,tourist ecological consumption characteristic and global climate change,this paper puts forward the conception of ecological security for tourist destination,and defines the conception in two ways by broad sense and narrow sense.Based on the theory and method of ecological footprint,it puts forward the ecological security measuring model,and taking the Jiuzhaigou National Nature Reserve(JNNR) as an example,it calculates and analyses the ecological security index and the intra and inter-regional impact on the JNNR in 2004.Four characteristics have been summarized:(1)The total tourist ecological footprint of the JNNR reaches 163514.0248hm2 in 2004,an increase of 115.1% in contrast to that of 2002;the per capita tourist ecological footprint is 0.105190274hm2 in 2004,an increase of 72.44%;the per capita residents ecological footprint of the JNNR is 0.994925hm2 in 2004,up by 3.47% compared with that of 0.9616hm2 in 2002.This indicates that tourism developed has produced some influence on the resident's consumption models.(2)The total tourist wastes ecological footprint of the JNNR is 46960.5678 hm2 in 2004,the per capita is 0.044543055 hm2,about 42.35% of the total tourist ecological footprint in 2004,and about 99.84% of the total tourist wastes ecological footprint are the CO2 emissions by the tourists.With the global climate change boiling up,the strict requirement of emission rights of CO2 and by international society,the rapidly developed trade market of CO2,and the high sensitivities to the CO2 about landscape of Jiuzhaigou,monitoring and research into various changes of CO2 for tourist destinations should be enhanced.(3)The ecological security index of the JNNR is from 1.093158 to 1.159388 in 2004,it is thus ecologically secure now,but the narrow sense of tourist destination ecological security index is higher than the broad sense,indicating that tourism development has not only exerted intra-regional but also interregional impact.(4)The increasing number of tourists,travel distance of tourists,changing consumption model of residents,and the increasing dependency on natural resources by local residents are the main factors influencing the ecological security of the JNNR in the future.",
        "keywords": [
            "global climate change",
            "jiuzhaigou",
            "ecological security",
            "ecological security index of tourist destination",
            "tourist ecological footprint"
        ],
        "authors": [
            {
                "name": "ZHANG Jin-he",
                "org": "College of National Territorial Resources and Tourism,Anhui Normal University,Wuhu ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "School of Geographic and Oceanographic Sciences of Nanjing University,Nanjing ,China"
            },
            {
                "name": "WANG Qun",
                "org": "College of National Territorial Resources and Tourism,Anhui Normal University,Wuhu ,China"
            }
        ],
        "venue": "Geographical Research",
        "year": 2008
    },
    "np39nlCk": {
        "id": "np39nlCk",
        "title": "Study on spatial differentiation of residents'perceptions and attitudes to tourism impacts:A case study of Huangshan Scenic Area",
        "abstract": "Residents' perceptions and attitudes to tourism impacts have been a hot study issue of both tourism geography and tourism sociology.In foreign tourism studies,the distance between the residents' habitations and tourists' attractions has been taken as a main factor in explaining the differences of residents' perceptions and attitudes to tourism impacts.However,similar studies are not found in domestic literatures in China.Considering the above conditions,taking Huangshan Scenic Area as an example,with the aid of questionnaire survey,using techniques of SPSS and Arc View GIS,spatial differentiation of residents' perceptions and attitudes to tourism impacts bought by Huangshan Scenic Area are revealed.The results indicate that residents in the hinterland of Huangshan Scenic Area show evident spatial differentiation of their perceptions and attitudes to tourism impacts brought by Huangshan Scenic Area.In determinate spatial scale,the intensity of residents perceptions and attitudes to positive tourism impacts wane and negative tourism impacts augment as the distance increases;in a more extensive space,affected by its tourism spatial structure and enclave tourism mode,the spatial differentiations of residents' perceptions and attitudes to tourism impacts brought by Huangshan Scenic Area take on \"W-shaped\" structure and \"M-shaped\" structure to positive tourism impacts and negative tourism impacts respectively.Also,the forming mechanisms leading to the above differentiation rules of residents' perceptions and attitudes to tourism impacts were analyzed,which are residents' knowledge of the scenic area,acting mechanism of tourist flows,transportation routes and residents' response to tourism development.It is thought that we can't oversimply deduce that the residents' perceptions and attitudes are \"distance decay\" or \"distance increase\".The tourism spatial structure and its subsequent effect should be taken into account when we analyze the spatial differentiation of residents' perceptions and attitudes to tourism impacts.The aim of this study is to reveal the spatial differentiation of tourism impacts,so as to offer some guidelines in optimizing regional tourism benefit and making community-oriented humanism regional tourism development strategies.",
        "keywords": [
            "spatial differentiation",
            "residents' perceptions and attitudes",
            "tourism impact",
            "Huangshan Scenic Area"
        ],
        "authors": [
            {
                "name": "LI Dong-he",
                "org": " Department of Tourism Management,Anhui University,Hefei ,China; School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": " School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "ZHANG Shang-zheng",
                "org": " Department of Tourism Management,Anhui University,Hefei ,China"
            },
            {
                "name": "FANG Chao",
                "org": " Tourism Administration of Huangshan City,Tunxi ,China"
            }
        ],
        "venue": "Geographical Research",
        "year": 2008
    },
    "xxr69aC9": {
        "id": "xxr69aC9",
        "title": "A Study on Random Coefficient Logit Model about Tourists' Destination Choice Based on Their Travel Motivation",
        "abstract": "Tourist destination choice is one of wider areas to study tourists' choice behavior.The available literature study and discussion about destination choice are conducted by using many models and theories such as society,economy and geography.Random coefficient logit model is widely adopted in the study of tourists' destination choice,but it lacks the study of restrictive and incentive effect on destination choice.The paper,with original data of sampling survey collected from domestic tourists of Jiangsu Province in 2002 to construct two Logistic Regression models,discusses the impact of three travel motivations(seeking for leisure and peaceful environment;visiting relatives and friends;business travel)on travel distance and travel cost.The study finds that those who seek for leisure and quiet environment tend to select long-distance destinations and are willing to increase their travel expenses.These who would like to visit relatives and friends while traveling are more willing to select tourist destinations close to their residences and do not tend to increase their spendings.And those who travel on business tend to select long-distance destinations and tend to increase their travel cost.",
        "keywords": [
            "destination choice",
            "travel distance",
            "motivation",
            "travel cost",
            "random coefficient logit model"
        ],
        "authors": [
            {
                "name": "ZHANG Hong-lei",
                "org": "Department of Land Resources and Tourism Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Land Resources and Tourism Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "CAO Jing",
                "org": "Department of Land Resources and Tourism Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "LIU Chuan-hua",
                "org": "Department of Land Resources and Tourism Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "SHI Chun-yun",
                "org": "School of Urban and Environmental Sciences,Xuzhou Normal University,Xuzhou ,China"
            },
            {
                "name": "YANG Yang",
                "org": "School of Hotel and Tourism Management,The Hong Kong Polytechnic University,Hong Kong ,China"
            }
        ],
        "venue": "Tourism Tribune",
        "year": 2008
    },
    "bkuEuNGE": {
        "id": "bkuEuNGE",
        "title": "Research on Spatial Structure of Eminent Tourism Resources in Ningzhenyang Region",
        "abstract": "In the way of spatial analysis presented by Stephen Smith,based on the data of investigation of tourism resources in Jiangsu Province in 2007,using the tool of spatial analysis in ArcGIS,the authors did some research on spatial structures of the eminent tourism resources in Ningzhenyang.Yangzhou and Zhenjiang had a typical pyramid-shaped hierarchy.Distribution of eminent tourism resources in Ningzhenyang showed clustering pattern,particularly Nanjing.After presenting the disadvantage of the traditional way,amended by weighted distance and expanding the scope of network,accessibility analysis showed that the traffic of Ningzhenyang was the most developed in Jiangsu Province,particularly Nanjing.",
        "keywords": [
            "evaluation of tourism resources",
            "dispersed analysis",
            "clustering analysis",
            "accessibility"
        ],
        "authors": [
            {
                "name": "CAO Jing",
                "org": "School of Geographic and Oceanographic Science,Nanjing University,Nanjing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "School of Geographic and Oceanographic Science,Nanjing University,Nanjing ,China"
            },
            {
                "name": "ZHANG Hong-lei",
                "org": "School of Geographic and Oceanographic Science,Nanjing University,Nanjing ,China"
            },
            {
                "name": "CHEN Cai-hong",
                "org": "School of Geographic and Oceanographic Science,Nanjing University,Nanjing ,China"
            },
            {
                "name": "LIU Chuan-hua",
                "org": "School of Geographic and Oceanographic Science,Nanjing University,Nanjing ,China"
            },
            {
                "name": "WANG Yan",
                "org": "School of Geographic and Oceanographic Science,Nanjing University,Nanjing ,China"
            },
            {
                "name": "TIAN Zhun-jun",
                "org": "School of Geographic and Oceanographic Science,Nanjing University,Nanjing ,China"
            },
            {
                "name": "WANG Lan",
                "org": "School of Geographic and Oceanographic Science,Nanjing University,Nanjing ,China"
            }
        ],
        "venue": "Resource Development & Market",
        "year": 2008
    },
    "r4amfGPZ": {
        "id": "r4amfGPZ",
        "title": "Relationship between the Place Attachment of Ancient Village Residents and Their Attitude towards Resource Protection——A Case Study of Xidi,Hongcun and Nanping Villages",
        "abstract": "The paper,taking three ancient villages Xidi,Hongcun and Nanping in southern Anhui as an example,measures the residents' place attachment and discusses the relationship between residents' place attachment and resource protection by constructing structural equation model.The result shows:1.residents' place attachment is composed of two dimensions——place dependence and place identity.2.place dependence has significantly positive influence on place identity.3.place dependence and place identity have significantly positive influence on residents' attitude towards resource protection.4.effect of place dependence on residents' attitude towards resource protection is realized through place identity and place identity plays a role of mediation.This study is of real instruction and referential significance to the resource protection of ancient villages and the construction of new residential areas in ancient villages.",
        "keywords": [
            "resource protection",
            "ancient village",
            "place attachment",
            "structural equation model",
            "resident"
        ],
        "authors": [
            {
                "name": "TANG Wen-yue",
                "org": "School of Tourism Management,Jiangxi University of Finance and Economics,Nanchang ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Land Resources and Tourism Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "LUO Hao",
                "org": "Department of Land Resources and Tourism Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "LU Song",
                "org": "College of National Territorial Resources and Tourism,Anhui Normal University,Wuhu ,China"
            },
            {
                "name": "YANG Xiao-zhong",
                "org": "College of National Territorial Resources and Tourism,Anhui Normal University,Wuhu ,China"
            }
        ],
        "venue": "Tourism Tribune",
        "year": 2008
    },
    "JuB3PPm6": {
        "id": "JuB3PPm6",
        "title": "Folklore Tourism in Urumuqi:A Case Study of International Bazaar Tourist Attraction",
        "abstract": "The folklore tourism has developed very quickly recently in Xinjiang,Urumqi,the capital of Xinjiang,has become the most active city in developing folklore tourism.This rearch took the international Dabazha of Urumqi as an example,where the fieldwork and questionnaires about folklore tourism were conducted.The study explored the advantages and present state of Urumqi folklore tourism,as well as some potential problems.Finally,some feasible suggestions were put forward.",
        "keywords": [
            "Urumqi",
            "folklore tourism",
            "International Bazaar"
        ],
        "authors": [
            {
                "name": "HAN Guo-sheng",
                "org": "School of Geography and Marine Science,Nanjing University,Nanjing ;School of Business Studies,Shandong University at Weihai,Weihai ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "School of Geography and Marine Science,Nanjing University,Nanjing "
            },
            {
                "name": "MA Jin-ping",
                "org": "School of Business Studies,Shandong University at Weihai,Weihai ,China"
            }
        ],
        "venue": "Journal of Arid Land Resources and Environment",
        "year": 2008
    },
    "QSXzkPBu": {
        "id": "QSXzkPBu",
        "title": "Research on Influence of Residents' Place Attachment on Positive Attitude to Tourism with A Mediator of Development Expectation: A Case of Core Tourism Community in Jiuzhaigou",
        "abstract": "Drawing from the literatures of Place Attachment and Anticipation Theory, a theoretical model of influence of place attachment of core tourism community's residents on supporting for tourism development with a mediator of expectation was proposed. The model consisted of five latent constructs of place attachment, development anticipation, benefits perception, cost perception and support attitude of residents, and seven path hypotheses and is based upon 188 questionnaires by residents of Jiuzhaigou, China, a major nature-based tourist destination. The model and the hypotheses were tested by utilizing a three-stage structural equation modeling approach involving Confirmatory Factor Analysis. The path analysis of each dimension revealed that path coefficients of each sub-dimension in place attachment and development expectation were consistent in two sub-SEMs, which implied the reasonability of the supposed sub-dimensions in each structural factor. The paper found that the influence on benefit perception or the cost perception of tourism by place attachment is different, and the former is always stronger than the later with or without an intermediary role in the case. Further, self-identity dimension, as the most directly perceived and likely identified dimension for residents, was found play the most important role in the SEM of residents' benefit perception, finding of which also rich the traditional evaluation model about social and cultural impact of tourism. There also had a positive support attitude from the residents with a benefit perception of tourism but a negative impact for supporting with a cost perception. The study also revealed that residents' expectation of tourism development as a mediator is subsistent and effective. Through the mediator of development expectation, the influence of residents' place attachment on perception as well as support of tourism was strengthened. Again, as a mediator, development expectation played a more important role in the SEM of residents' benefit perception than that in cost side.",
        "keywords": [
            "Mediatory Effect",
            "Resident",
            "Tourism Community",
            "Place Attachment",
            "Jiuzhaigou",
            "Tourism Support",
            "Development Expectation"
        ],
        "authors": [
            {
                "name": "XU Zhenxiao",
                "org": " School of Geographic and Oceanographic Sciences, Nanjing University, Nanjing , China"
            },
            {
                "name": "ZHANG Jie",
                "org": " School of Geographic and Oceanographic Sciences, Nanjing University, Nanjing , China"
            },
            {
                "name": "CAO Jing",
                "org": " School of Geographic and Oceanographic Sciences, Nanjing University, Nanjing , China"
            },
            {
                "name": "ZHANG Honglei",
                "org": " School of Geographic and Oceanographic Sciences, Nanjing University, Nanjing , China"
            }
        ],
        "venue": "Acta Geographica Sinica",
        "year": 2009
    },
    "pftcEbNQ": {
        "id": "pftcEbNQ",
        "title": "Social Network Structure and Cooperation Model of Cross-border Tourism Region: A Case Study of Tiantangzhai in Dabieshan",
        "abstract": "Cross-border tourism region is a geographic unit which has large tourism development potential and complex management object, and becomes a new research focal point in tourism geography. Based on the Inter-Organizational Relationships (IORs) and social network theory, the paper indicates that the spatial cooperation behavior among cross-border tourism regions is essentially the network construction and reorganization of contacts and exchanges between the cross-border tourism organizations. Using the corresponding social network evaluating indicator system, the paper makes an empirical analysis for cross-border tourism region network structure and cross-border cooperation in the Tiantangzhai of Dabieshan, and then the conclusion is verified by core-periphery model. The results show that: (1) In terms of the network density, the whole Tiantangzhai network is smaller compared with the local network density, showing a weak tie between the administrative areas and a strong tie inside the administrative area, meanwhile structural holes are found. The network density between the low level administrative areas is bigger than that between the upper ones. The more cross-border dimensions are, the smaller the network density is. This reflects that there is a significant border effect in the cross-border tourism activity. (2) As to the network degree, the local degree is the biggest, followed by the global degree, and the border degree is the smallest. It is proved that tourism administrative region economy is an influential phenomenon. (3) According to Francisco's integrated model of IORs, the paper discovers that the cross-border tourism cooperation has transferred from a weak phase to a medium phase in Tiantangzhai. To enhance cooperation in Tiantangzhai cross-border region, concrete measures should be taken to achieve the aim of sustainable development by reducing the transactional costs, strengthening the conformity among departments concerned, building the good external environments, and setting up the cross-border tourism alliances.",
        "keywords": [
            "Cross-border cooperation",
            "Cross-border tourism region",
            "Inter-Organizational Relationships (IORs)",
            "Network construction",
            "Social network theory",
            "Tiantangzhai"
        ],
        "authors": [
            {
                "name": "YANG Xiaozhong",
                "org": " Department of Land Resources and Tourism Sciences, Nanjing University, Nanjing , China"
            },
            {
                "name": "ZHANG Jie",
                "org": " Department of Land Resources and Tourism Sciences, Nanjing University, Nanjing , China"
            },
            {
                "name": "WU Tiehong",
                "org": " Department of Land Resources and Tourism Sciences, Nanjing University, Nanjing , China"
            }
        ],
        "venue": "Acta Geographica Sinica",
        "year": 2009
    },
    "MZCMHdff": {
        "id": "MZCMHdff",
        "title": "Study on the Spatial Disturibution and Dynamic Mechanism of China's Tourism Websites",
        "abstract": "Based on the era background concerning increasingly fierce tourism competition,travel mode tending to be individualistic,informatization of tourism marketing and management and people-oriented development,the paper makes a study on the regional difference of the spatial distribution of China's tourism websites and characteristics of spatial scale structure——the number of tourism websites decreases from coastal areas of East China to Central and West China and most of them concentrate in provincial cities and tourism-developed cities.By using SPSS14.0 qualitative analysis,the paper sums up the mathematical and statistical relationship between regional economy,information and technical level,number of tourism enterprises,number of tourist arrivals and scale distribution of China's tourism websites.It summarizes two factors—tourism enterprises and tourists that influence the spatial distribution of tourism websites.",
        "keywords": [
            "spatial distribution",
            "tourism website",
            "spatial scale structure",
            "dynamic mechanism"
        ],
        "authors": [
            {
                "name": "CHENG Shao-wen",
                "org": " School of Geographic and Oceanographic Sciences, Nanjing University, Nanjing , China"
            },
            {
                "name": "ZHANG Jie",
                "org": " School of Geographic and Oceanographic Sciences, Nanjing University, Nanjing , China"
            },
            {
                "name": "LIANG Yue-lin",
                "org": " Management School of Geology University of China, Wuhan , China"
            },
            {
                "name": "HAN Guo-sheng",
                "org": " School of Geographic and Oceanographic Sciences, Nanjing University, Nanjing , China"
            },
            {
                "name": "YANG Zhao",
                "org": " School of Geographic and Oceanographic Sciences, Nanjing University, Nanjing , China"
            }
        ],
        "venue": "Tourism Tribune",
        "year": 2009
    },
    "YyJZ8cS0": {
        "id": "YyJZ8cS0",
        "title": "The Characteristics Studies of the Tourist Flows’ Landscape Preference in Jiuzhaigou",
        "abstract": "Using the scenic spot of Jiuzhaigou as an example,this article chooses six main types of landscapes,and basing on the field surveys,analyzes the tourists’judgment towards landscape preference and explores its features by employing software of DPS and SPSS12.0.So we can get the following conclusions:First,if the tourists’market is carefully divided,tourists’judgment towards landscape preference will vary from area to area.However,if tourists is divided by demographic features,all the tourists as the subject of landscape preference are greatly influenced by the object of the landscape preference.",
        "keywords": [
            "the characteristics of the landscape preference",
            "the object of the landscape preference",
            "the tourist flows",
            "Jiuzhaigou"
        ],
        "authors": [
            {
                "name": "Chen Youjun",
                "org": "The Department of Tourism Planning Tourism College of Zhejiang,Hangzhou ,China"
            },
            {
                "name": "Zhang Jie",
                "org": "School of Geographical and Marine Sciences,Nanjing University,Nanjing ,China"
            }
        ],
        "venue": "Henan Science",
        "year": 2009
    },
    "cs6ddy5C": {
        "id": "cs6ddy5C",
        "title": "PROGRESS AND PROSPECT ABOUT DOMESTIC RESEARCH ON SPATIAL DIFFERENTIATION OF TOURISM PHENOMENA",
        "abstract": "After a review of domestic research on spatial differentiation of tourism phenomena,it is thought that the studies of tourism geography on spatial differentiation of tourism phenomena in China focus on such components of tourism system as tourist attractions,tourist origins and tourist flows,tourism industry and tourist resorts,while the equivalent studies on the regional effects of tourism development is insufficient.Based on a comparison with the equivalent studies abroad,combined with the tendencies of tourism development and research both domestic and abroad,it is proposed that tourism geography in China should pay more attention to the study of tourism-impact spatial differentiation.Also,the significances and main contents of tourism impact spatial differentiation study are addressed.The significances of the study can be concluded as following:(1) international and domestic tendency has led a shift of focus of both tourism development and tourism study,so the study of tourism impact spatial differentiation is accordant with the times background;(2) the study of tourism impact spatial differentiation offers a new visual angle for assessing the practical effects of regional tourism development objectively;(3) the study of tourism impact spatial differentiation is a main content of both tourism geography and tourism science.Also,some main contents of the study of tourism impact spatial differentiation are suggested:(1) the study of basic theories;(2) the study of indicators and mesures of tourism impact spatial differentiation;(3) the study of spatial differentiation rules of tourism impact;(4) the study of forming mechanisms of tourism impact spatial differentiation;(5) the study of optimizing and adjusting mechanisms of tourism impact spatial differentiation.The aim of the paper is to promote a further development of tourism geography and tourism science studies in China.",
        "keywords": [
            "tourist flows",
            "tourism geography",
            "spatial differentiation",
            "tourism impact"
        ],
        "authors": [
            {
                "name": "LI Dong-he",
                "org": "Department of Tourism Management,Anhui University,Hefei ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,China"
            }
        ],
        "venue": "Human Geography",
        "year": 2009
    },
    "ABLQB3zC": {
        "id": "ABLQB3zC",
        "title": "Concentration on Problems within Spatial Pattern of Tourist Flow in the Way of Critical Thinking",
        "abstract": "Tourist flow is a basic question of tourism geography.Examinations on spatial patterns of tourist flow have long been a hot issue since the 1950s.This article classifies the spatial patterns of tourist flow into three basic theories,i.e.,concentric zone theory,centre-periphery theory,spatial diffusion theory,based on literature review.Then,six main issues existing in tourism studies are revealed with critical thinking with the aim to deepen the construction of tourist flow from theoretical perspective.(1) There exists confusion between \"regional perspective\" for tourist flow and \"individual tourists perspective\" for individual tourists.(2) A phenomenon of \"dual trap\" dissevers the intrinsic relationship between tourist origin and tourist destination.(3) One-way arbitrary specification,i.e.,regions are specified functioning absolutely as tourist origins or as tourist destinations.So it contradicts the known facts that regions have double functions attracting tourists while emitting tourist flow to some extent.(4) Intra-regional tourist flow and inter-regional tourist flow,which have different connotations and meanings,have not been scientifically analyzed.(5) Diagnoses of basic pointing types and quantitative measurement of directional bias are also absent.(6) Spatial diffusion of tourist flow is weaker than the foreign countries,especially for multi-destination travel.",
        "keywords": [
            "spatial pattern",
            "tourist flow",
            "dual trap",
            "directional bias",
            "tourist O-D system"
        ],
        "authors": [
            {
                "name": "ZHONG Shien",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing  China"
            },
            {
                "name": "ZHANG Jie",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing  China"
            },
            {
                "name": "REN Lixiu",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing  China"
            },
            {
                "name": "LI Qian",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing  China"
            },
            {
                "name": "DONG Xuewang",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing  China"
            },
            {
                "name": "LI Min",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing  China"
            }
        ],
        "venue": "Progress in Geography",
        "year": 2009
    },
    "jckHBOvF": {
        "id": "jckHBOvF",
        "title": "Spatial Pattern of Domestic Traveling of Rural Residents in China",
        "abstract": "Traditional researches have looked into rural areas and rural residents from \"supply\" perspectives when whose \"demand\" roles are often bypassed.So this article examines the basic spatial patterns from static scales with ternary graph method,RA index,dominant flow analysis.Then,directional bias is brought into focus on the spatial diffusion behavior from dynamic perspectives.The four principal observations are verified with the case study of the Chinese rural residents.Some interesting conclusions are generated:1) Because of restrictions of discretionary income,rural residents take on a high tendency to travel in the province where they lived.The proportion of intra-regional is far low than the West Europe and more or less parallels with the average level of the world.2)Inter-provincial travelers mainly flow to Jing-Jin-Liao area,Su-Zhe-Hu area,Yue-Qiong area and Shaanxi area.3)The vast central and west areas of China become catchment areas with the tourist flows concentrated from bottom to up,and then the tourist flows diffuse in the east parts of China with the main spatial diffusion firstly pointing to cities followed by the second pointing type,i.e.seaside pointing.",
        "keywords": [
            "concentration",
            "rural residents",
            "tourist flow",
            "ternary graph method",
            "directional bias",
            "dominant flow analysis"
        ],
        "authors": [
            {
                "name": "ZHONG Shi-en",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing "
            },
            {
                "name": "ZHANG Jie",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing "
            },
            {
                "name": "REN Li-xiu",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing "
            },
            {
                "name": "ZHANG Hong-lei",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing "
            },
            {
                "name": "WANG Lan",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing "
            },
            {
                "name": "ZHOU Qiang",
                "org": "Jiangsu Provincial Tourism Bureau,Nanjing ,China"
            }
        ],
        "venue": "Geography and Geo-Information Science",
        "year": 2009
    },
    "b0uYXQgM": {
        "id": "b0uYXQgM",
        "title": "A Study Review of Cognitive Maps of Tourists",
        "abstract": "Cognitive map is an important study area in behavioral geography. The paper,based on the concept system of cognitive map and study of geography and psychology on cognitive map,sums up tourists' study on cognitive maps both at home and abroad in the past thirty years. The study finds:1.Tourists' cognitive maps are integrated images of tourism environment which are spatially oriented,dynamic and three-dimensional. 2. Tourists who are influenced by characters of tourist activities and categories of tourist destinations have formed unique cognitive map categories and spatial structure. 3. There are significant differences between tourists' environmental learning(short-term learning) and ordinary environmental learning in terms of acquiring speed and process of getting environmental knowledge. 4. Human influencing factors are mainly manifested by tourists' types in the process of the formation of tourists' cognitive maps. 5. Methods and technologies fitting real-world setting are usually applied in current study. 6. Study of tourists cognitive maps are still at the immature stage,mainly manifested by theories,contents and methodologies of research. Finally,some topics in multi-disciplines about tourists' cognitive maps are put forward. Study of tourists' cognitive maps are of certain theoretical and practical significance to tourism planning,tourism destination marketing and study of tourism spatial behavior.",
        "keywords": [
            "spatial orientation",
            "tourists' cognitive map",
            "cognitive mapping",
            "environmental learning",
            "integrated image"
        ],
        "authors": [
            {
                "name": "JIANG Zhi-jie",
                "org": "College of Geography,Nanjing University,Nanjing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "College of Geography,Nanjing University,Nanjing ,China"
            },
            {
                "name": "HAN Guo-sheng",
                "org": "College of Geography,Nanjing University,Nanjing ,China"
            },
            {
                "name": "CAO Jing",
                "org": "College of Geography,Nanjing University,Nanjing ,China"
            }
        ],
        "venue": "Tourism Tribune",
        "year": 2009
    },
    "TX5AJYqd": {
        "id": "TX5AJYqd",
        "title": "The temporally comparative study of residents' perceptions and attitudes in ancient villages:A case study of Xidi Village,one of the world cultural heritage sites",
        "abstract": "Study on the residents' perceptions and attitudes to tourism destinations have been a lasting study topic of Tourism Geography.A temporally comparative study of residents' perceptions and attitudes is one of two future study subjects in the study area.Ancient villages are a special type of tourism destination.It is particularly important and urgent for ancient villages' tourism sustainable development and world heritage protection to study residents' perceptions and attitudes.Taking the world cultural heritage-Xidi village-as an example,the paper analyzes the temporal change of resort residents' perceptions and attitudes.The results are as follows.1)As time flies,residents' family income in Xidi village has dramatically increased,in which the proportion of tourism profit(tourism ticket profit and tourism business profit)in family total income has apparently elevated.This indicates that from respective aspect,the extent of residents' reliance on tourism industry has gradually strengthened.2)As time runs,all the residents in Xidi village pay more and more attention to tourism social-cultural and environmental effect.It suggests that this change conforms to mankind's general perception rule,from formal to substantive,from economic to cultural and from matter to spirit.3)The temporal changes of Xidi residents' perceptions and attitudes are from collective impacts of diverse aspects,such as individual,tourist scenic spot and government.These detailed influencing factors are formal and substantive rationality,interior management of tourist scenic spot,exterior space compete of tourist scenic spot,construction of new villages and government policy of alluring foreign capital.Furthermore,it clarifies the influencing factors and shaping mechanism of temporal changes of tourism destination residents' perceptions and attitudes.",
        "keywords": [
            "influencing factors",
            "residents' perception",
            "tourism impact",
            "Xidi",
            "temporal change"
        ],
        "authors": [
            {
                "name": "LU Song",
                "org": "College of Territorial Resource and Tourism,Anhui Normal University,Wuhu ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "SU Qin",
                "org": "College of Territorial Resource and Tourism,Anhui Normal University,Wuhu ,China"
            }
        ],
        "venue": "Geographical Research",
        "year": 2009
    },
    "yB8tOK45": {
        "id": "yB8tOK45",
        "title": "The spatial pattern evolution of the inbound tourism economic development level and the causes in China——Based on the inbound tourism economic entropy analysis",
        "abstract": "Based on the meaning of the district entropy,the author constructed the inbound tourism economic entropy,then took it as the calculation tool,selected the inbound tourism related data of the 1995,2000 and 2005 as the time cross-sections,discussed the characteristics of the spatial pattern evolution of the level of inbound tourism economic development of China.The correlation analysis method was used to analyze the reasons.These characteristics are: ① With the economic development,the area of the inbound tourism economic prosperity was gradually enlarging a prosperous areas and backward areas of bipolar evolution pattern.② Inbound tourism economy experienced the spatial pattern evolution process from dispersed to concentration to the proliferation in China.③ From east to west the spatial pattern evolution has been showing a significant difference between the gradient zone.The significant factors influencing the current spatial pattern of the inbound tourism economic development level were the attraction of high-grade tourism resources,the socio-economic level,the extent of the development of business services,the throughput of air passengers belongs,the scale of the first major cities,and the urbanization level of the cities.The effections of the factors,such as the passenger volume and throughput which represented the accessibility,the primate city and so on were ont obvious.",
        "keywords": [
            "the correlation analysis",
            "the spatial pattern",
            "inbound tourism economy",
            "the district entropy"
        ],
        "authors": [
            {
                "name": "WU Tiehong",
                "org": "Department of Land Resources and Tourism Science,Nanjing University,Nanjing ,P.R.China;Tourism Department of College Humanities,Inner Mongolia University,Huhhot ,P.R.China"
            },
            {
                "name": "ZhANG Jie",
                "org": "Department of Land Resources and Tourism Science,Nanjing University,Nanjing ,P.R.China"
            },
            {
                "name": "LI Wenjie",
                "org": "College of Geographic Science,Inner Mongolia Normal University,Huhhot ,P.R.China"
            },
            {
                "name": "CAO Jing",
                "org": "Department of Land Resources and Tourism Science,Nanjing University,Nanjing ,P.R.China"
            },
            {
                "name": "LIU Zehua",
                "org": "Department of Land Resources and Tourism Science,Nanjing University,Nanjing ,P.R.China"
            }
        ],
        "venue": "Journal of Arid Land Resources and Environment",
        "year": 2009
    },
    "iPD85mnw": {
        "id": "iPD85mnw",
        "title": "SPATIAL BEHAVIOR CHARACTERISTICS OF URBAN PLAZA USERS——A Case Study of Taihui Lake Plaza,Wuxi City",
        "abstract": "The spatial patterns and processes of the search for human recreation are critical to recreation geography.There are many researches on spatial behavior of recreationist and spatial structure of the generating areas at present.However,those are mostly about the spatial structure of medium or large scale generating market while few about small scale for the interurban daily leisure activities.So it is very important to understand the leisure behavior of urban residents and the overall arrangement of urban leisure spaces.This paper employs the indirect distance which is transformed by travel time and the velocity of its corresponding traffic mode,to examine the spatial behavior characteristics of urban plaza's users with case survey of Taihu Lake Plaza,Wuxi,Jiangsu Province of China.Based on the above,the paper reveals that percents of plaza users decrease with travel time and distance increasing.However,there are some differences between percent change with travel time and spatial distance.Time-distance mostly concentrates in 30mins,but spatial distance extends abroad.Also,the paper finds that they have different decay modes as in the whole but still with some similarities.Curves of physical health training and city park activities are close to the plaza leisure activities,especially for the former.The number of consumers in Supermarkets has the slowest attenuation but that in bars has the fastest.In addition,the paper puts forward a spatial structure mode of obvious belts because of different travel modes.Considering time and traffic mode factors,the authors can more accurately measure the influence of distance on urban plaza activities.Above results and conclusion are of great significance to effectively estimate urban plazas' radius and plan urban public leisure space,and might be a great supplement about urban public leisure space research.",
        "keywords": [
            "urban plaza",
            "distance decay",
            "spatial characteristics",
            "critical distance",
            "time-distance"
        ],
        "authors": [
            {
                "name": "TIAN Zhun-jun",
                "org": "Shool of Geographic and Oceanographic Sciences,Nanjing University,Nanjing  China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Shool of Geographic and Oceanographic Sciences,Nanjing University,Nanjing  China"
            },
            {
                "name": "SHI Chun-yun",
                "org": "School of Urban and Environmental Sciences,Xuzhou Normal University,Xuzhou ,China"
            },
            {
                "name": "CAO Jing",
                "org": "Shool of Geographic and Oceanographic Sciences,Nanjing University,Nanjing  China"
            }
        ],
        "venue": "Human Geography",
        "year": 2009
    },
    "1NDKV5N1": {
        "id": "1NDKV5N1",
        "title": "RESEARCH ON THE FEATURES OF SPATIAL DISTRIBUTION OF TOURISTS' EXPENDITURE IN THE DESTINATION OF SUZHOU",
        "abstract": "So far, there have been many results about the model of the tourist's spatial distribution at home and abroad.At the same time, several models of the distribution of the resident's small-scale open space have been researched during the past study.However, most of the researches still focus on the macroscopic geographic models, such as gravity model and model of distance decay.Few researches are conducted on tourists' expenditure.Thus, we try to find an inner mechanism and establish a spatial model depending on tourists' expenditure.In general, the following 6 factors which impact on the tourist's expenditure are:tourists' income, price levels of the destination, the fluctuations of currency exchange rate, tourist's demographic features, special events and other factors.We find that no research has been made on the impact of tourists' expenditure in terms of the factor of pure distance.Tourists' expenditure covers two parts:the cost in destination and the cost on the way.To avoid the impact of the correlation between the total expenditure and the distance, we study tourists' expenditure in destination.Choosing 3337 available samples in sampling survey offered by Jiangsu Travel Bureau, using a series of statistical methods, such as the correlation analysis, etc., based on the factors of social economy, we educe and explain the two stages of the curve of spatial distribution of tourists' expenditure in the destination of Suzhou:the increasing stage and the stagnant stage.The result of our using the same method to analyse the samples of the intraprovincial tourists' cost in destination has verified the reliability of the spatial distribution.Correlation coefficient R between tourists' cost in destination and the distance is 0.712.And the correlation is significant at 0.01 level.Within 250 kilometers, the correlation is more intense.After that, the curve is becoming more and more gentle.This is consistent to previous research.Finally, in the view of segment cost, a further study shows that accommodation and restaurant make largest contribution to the whole spatial distribution, and the less important part is recreation.Other factors' impact is not so obvious.",
        "keywords": [
            "segment cost",
            "features of spatial distribution",
            "expenditure in destination",
            "tour distance"
        ],
        "authors": [
            {
                "name": "CAO Jing",
                "org": "School of Geographic and Oceanographic Science,Nanjing University,Nanjing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "School of Geographic and Oceanographic Science,Nanjing University,Nanjing ,China"
            },
            {
                "name": "WANG Lan",
                "org": "School of Geographic and Oceanographic Science,Nanjing University,Nanjing ,China"
            },
            {
                "name": "WU Tie-hong",
                "org": "School of Geographic and Oceanographic Science,Nanjing University,Nanjing ,China"
            },
            {
                "name": "XU Zhen-xiao",
                "org": "School of Geographic and Oceanographic Science,Nanjing University,Nanjing ,China"
            },
            {
                "name": "QI Qiu-yin",
                "org": "School of Geographic and Oceanographic Science,Nanjing University,Nanjing ,China"
            }
        ],
        "venue": "Human Geography",
        "year": 2009
    },
    "Fi8hIyqk": {
        "id": "Fi8hIyqk",
        "title": "Research on Distortion of Tourist's Cognitive Distance in Jiuzhaigou",
        "abstract": "The term cognitive distance refers to people's beliefs about distances between places in large-scale spaces that are far apart and not visible from each other.In the article,we put forward five hypothesis according to past research conclusion and related theory.With the survey data of Jiuzhaigou,we use the statistical method of box counting,regression analysis and independent-samples T test to verify the five hypothesis.In general,distortion of tourist's cognitive distance is plus.Distortion of tourist's cognitive distance is increasing with the increase of tour distance.Distortion of tourist's cognitive distance is significantly influenced by travel times and transportation,but not significantly influenced by travel mode.Finally,we use hierarchical theory and nonhierarchical theory to discuss the influence mechanism of the distortion of tourist's cognitive distance.",
        "keywords": [
            "transportation mode",
            "travel times",
            "travel mode",
            "distortion of cognitive distance",
            "tour distance"
        ],
        "authors": [
            {
                "name": "Wang Lan",
                "org": "School of Geographic and Oceanographic Science,Nanjing University,Nanjing ,China"
            },
            {
                "name": "Zhang Jie",
                "org": "School of Geographic and Oceanographic Science,Nanjing University,Nanjing ,China"
            },
            {
                "name": "Cao Jing",
                "org": "School of Geographic and Oceanographic Science,Nanjing University,Nanjing ,China"
            },
            {
                "name": "Zhang Honglei",
                "org": "School of Geographic and Oceanographic Science,Nanjing University,Nanjing ,China"
            }
        ],
        "venue": "Journal of Beijing International Studies University",
        "year": 2009
    },
    "ch4Uu0Kv": {
        "id": "ch4Uu0Kv",
        "title": "A STUDY OF THE PROVINCIAL EMISSIVENESS IN CHINA BASED ON THE SOCIO-ECONOMIC PROPERTIES——WITH CONTRAST BETWEEN CHINA AND OTHER COUNTRIES",
        "abstract": "Emissiveness can be classified to two categories: tourist emissivness and origin emissiveness. Tourist emissiveness emphasizes particularly on tourists which are the principal part of recreation from microcosmic dimension, while origin emissiveness is studied from macroscopical dimension. Tourism geographers have paid so much attention to tourist emissiveness with little regard to origin emissiveness. So this paper examines some of the geographical dimensions of the provincial emissiveness in china based on the socio-economic properties. The discussions and conclusions are as follows: ① 31 provinces in china are selected as study objects and 21 socio-economic variables are choosed describing the provincial properties. The hypothesis is validated of which is the origin’s socio-economic properties determines its emissiveness, tourism is a socio-economic phenomenon essentially. Socio-economic scale facor, residents’ living standard factor and connective level factor are the main socio-economic properties. Travel happens after the spatial interaction of origin emissiveness and destination attractiveness, whether or not is the destination attractiveness also be determined by the socio-economic properties? The theory of socio-economic phenomenon of tourism should be studied thoroughly; ②When origin emissiceness is decomposed to three dimensionalities which are socio-economic scale facor, residents’ living standard factor and connective level factor, the result shows that origin emissiveness in different dimensions have different mechanisms. ③The pattern of domestic tourism emissiveness in china is that travellers’ quantity is tremendous and travel expenditure is low, short excursions are the top choice. So the orientation of domestic tourist market and marketing for most destinations should focus on their own provinces,adjacent provinces and five other provinces with hign emissiveness of which are Beijing, Shanghai,Tianjin,Jiangsu and Zhejiang. Tourism geography should attach much more importance to \"day trip\",\"weekend trip\" and\"leisure trip\", because such recreational behavior in medium and small dimensions have more commercial meaning and can help the tourism geography develop. ④60 percent accumulated of emissiveness is agglomerate in 4 tourists generating region: Ji’lu’yu, Su’zhe’hu, E’xiang’yue and Sichuan of which Ji’lu’yu and Su’zhe’hu are the main tourist generating region. Since 1999. domestic tourism in china develops very quickly and tourism will be an important socio-economic activity, tourism industry will also confront new opportunities. So the 4 tourist generating region should increase the devotion into such areas of tourism productivity: star-rated hotels,travel agencies and so on.",
        "keywords": [
            "emissiveness",
            "distance decay",
            "ternary graph",
            "factor analysis",
            "spatial form",
            "hypothesis"
        ],
        "authors": [
            {
                "name": "ZHONG Shi-en",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,Jiangsu,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,Jiangsu,China"
            },
            {
                "name": "REN Li-xiu",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,Jiangsu,China"
            },
            {
                "name": "LUO Hao",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,Jiangsu,China"
            },
            {
                "name": "LI Min",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,Jiangsu,China"
            },
            {
                "name": "DONG Xue-wang",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,Jiangsu,China"
            }
        ],
        "venue": "Economic Geography",
        "year": 2009
    },
    "uZBGA4tZ": {
        "id": "uZBGA4tZ",
        "title": "Study System about Residents' Perceptions and Attitudes to the Tourism Impacts and its Reflection on Tourism Development in Ancient Villages",
        "abstract": "Study on the residents' perceptions and attitudes to tourism destinations have been a lasting study topic of Tourism Sociology and Tourism Geography.Based on the literature analysis,the paper summarizes the study system about residents' perceptions and attitudes to the tourism impacts,which is made up of residents' perceptions scales,perceptions differences and its predictors,cluster analysis,the temporal and spatial analysis of residents' perceptions,residents' perceptions on community life quality and models of residents' perceptions and attitudes.The importance of residents' perceptions on sustainable tourism development is also analyzed.Furthermore,the paper analyzes the important reflection of residents' perceptions on the sustainable tourism development and heritage protection in ancient villages.Community tourism is an effective approach in boosting community development ability and heritage in ancient villages,and tourism community characteristics determine that residents are in the key position in community tourism sustainable development and heritage protection.So effective measures should be taken to improve ancient villages residents' perceptions and attitudes.",
        "keywords": [
            "sustainable tourism",
            "ancient villages",
            "residents' perceptions",
            "study system"
        ],
        "authors": [
            {
                "name": "LU Song",
                "org": "College of Territorial Resource and Tourism,Anhui Normal University,Wuhu ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,China"
            }
        ],
        "venue": "Journal of Anhui Normal University(Natural Science)",
        "year": 2009
    },
    "JPJ89G3X": {
        "id": "JPJ89G3X",
        "title": "Research on influence of residents place attachment on positive attitude to tourism with a mediator of development expectation: A case of core tourism community in jiuzhaigou",
        "abstract": "Drawing from the literatures of Place Attachment and Anticipation Theory, a theoretical model of influence of place attachment of core tourism community's residents on supporting for tourism development with a mediator of expectation was proposed. The model consisted of five latent constructs of place attachment, development anticipation, benefits perception, cost perception and support attitude of residents, and seven path hypotheses and is based upon 188 questionnaires by residents of Jiuzhaigou, China, a major nature-based tourist destination. The model and the hypotheses were tested by utilizing a three-stage structural equation modeling approach involving Confirmatory Factor Analysis. The path analysis of each dimension revealed that path coefficients of each sub-dimension in place attachment and development expectation were consistent in two sub-SEMs, which implied the reasonability of the supposed sub-dimensions in each structural factor. The paper found that the influence on benefit perception or the cost perception of tourism by place attachment is different, and the former is always stronger than the later with or without an intermediary role in the case. Further, self-identity dimension, as the most directly perceived and likely identified dimension for residents, was found play the most important role in the SEM of residents' benefit perception, finding of which also rich the traditional evaluation model about social and cultural impact of tourism. There also had a positive support attitude from the residents with a benefit perception of tourism but a negative impact for supporting with a cost perception. The study also revealed that residents' expectation of tourism development as a mediator is subsistent and effective. Through the mediator of development expectation, the influence of residents' place attachment on perception as well as support of tourism was strengthened. Again, as a mediator, development expectation played a more important role in the SEM of residents' benefit perception than that in cost side.",
        "keywords": [
            "Development expectation",
            "Jiuzhaigou",
            "Mediatory effect",
            "Place attachment",
            "Resident",
            "Tourism community",
            "Tourism support"
        ],
        "authors": [
            {
                "name": "Zhenxiao Xu",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Wall Geoffrey",
                "org": "University of Waterloo(University of Waterloo,Univ of Waterloo),Waterloo,Canada"
            },
            {
                "name": "Jing Cao",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Honglei Zhang",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            }
        ],
        "venue": "Acta Geographica Sinica",
        "year": 2009
    },
    "sMELs6aa": {
        "id": "sMELs6aa",
        "title": "On the Relationship between Tourism Destination Attributes and Tourists' Perceived Attitude,Post-purchase Behavior——A Case of Jiuzhaigou Landscape Area",
        "abstract": "It is very important to identify the effectiveness of destination attributes on tourism destination image, tourists' satisfaction and their intention to revisit and willingness to recommend. Taking Jiuzhaigou landscape area as a case study, and by adopting methods of factor analysis and regression analysis, we find: 1.The local attributes of Jiuzhaigou landscape area can be divided into three dimensions of resource values and the atmosphere of humane environment, reception service, natural tourism resources and environment. 2. Not all of the local attributes have significant effect on the formation of its image, tourists' satisfaction and their intention to revisit and willingness to recommend. Only 11 out of 18 attributes are related with tourists' perceived attitude and their post-purchase behavior, which can be used to construct structural model. 3. The effectiveness of local attributes and their perceived quality are not completely coupled. The study intends to offer suggestions for tourism development and management and help tourism destinations to take appropriate measures and marketing strategies.",
        "keywords": [
            "destination image",
            "intention to revisit",
            "tourism destination attribute",
            "tourists' satisfaction",
            "willingness to recommend"
        ],
        "authors": [
            {
                "name": "WU Tie-hong",
                "org": "Department of Land Resources and Tourism Science,Nanjing University,Nanjing ,China;Tourism Department,Inner Mongolia University,Huhhot ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Land Resources and Tourism Science,Nanjing University,Nanjing ,China"
            },
            {
                "name": "ZHANG Hong-lei",
                "org": "Department of Land Resources and Tourism Science,Nanjing University,Nanjing ,China"
            },
            {
                "name": "CAO Jing",
                "org": "Department of Land Resources and Tourism Science,Nanjing University,Nanjing ,China"
            },
            {
                "name": "CAI Yong-shou",
                "org": "The Management Office of Jiuzhaigou Landscape Showplace,Jiuzhaigou County ,China"
            },
            {
                "name": "YANG Qing-xia",
                "org": "The Management Office of Jiuzhaigou Landscape Showplace,Jiuzhaigou County ,China"
            }
        ],
        "venue": "Tourism Tribune",
        "year": 2009
    },
    "0QW0fXP5": {
        "id": "0QW0fXP5",
        "title": "Spatial concentration of domestic tourist flow of Chinese rural residents",
        "abstract": "Tourist flow is a basic question of tourism geography.Accordingly,spatial concentration of tourist flow draws great attention.But present studies have not distinguished its basic types concerning inherent mechanisms.This paper brings in the delimitation technique of Jansen-Verbeke's paper on the basis of domestic tourist flows of Chinese rural residents in 2003~2005.Accordingly,spatial concentration of tourist flow is classified into two basic types,that is,intra-provincial concentration and special-provincial concentration.The results can be obtained as follows: (1) Intra-provincial concentration is constrained by multi-dimensional elements,including provincial size,spatial accessibility,hierarchy of city,socio-economic factors,potential distribution of population,and motivation of travelling.As to the period 2003~2005,about 70% of tourist flows are concentrated intra-provincially.Practically,this examination is helpful to the formation of development strategy called \"intra-provincial tourism\".Although man-made delimitation contradicts the limitless behavior of travelling,it accords with the true fundamental characteristics. (2) Dissymmetrical flowing of inter-provincial tourist flow induces the formation of special-provincial concentration,characterized by the special pointing which reflects the inter-provincial spatial interaction.Inter-provincial tourist flows mostly inclined to move to neighbouring provinces,to economically-developed regions,to large regional centres in economic,historical and cultural perspectives,to coastal areas.\"Polycentric and asymmetrical tourism system\" has elementarily formed and takes on a stable spatial pattern.Its \"centre-periphery\" characters have different meanings for centre(i.e.eastern coastal areas) and periphery(i.e.central and western China).Central areas bear great weight of the large-scale inbound tourist flow while peripheral areas seek development due to regional economic disparities caused by development of tourism. (3) To analyze the evolving tendency from dialectic angle,this paper anticipates that intra-provincial concentration will slow down as special-provincial concentration with the increase of people's emissiveness,continual experiments of people's leisure plan,and the increasingly perfect full paid vacation system.Inter-provincial flowing of tourist flow will be much more frequent in the future.",
        "keywords": [
            "concentration",
            "rural residents",
            "tourism system",
            "tourist flow",
            "centre-periphery pattern",
            "dominant flow analysis technique"
        ],
        "authors": [
            {
                "name": "ZHONG Shi-en",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "ZHOU Qiang",
                "org": "Jiangsu Provincial Tourism Bureau,Nanjing ,China"
            },
            {
                "name": "DONG Xue-wang",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "LI Min",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "LIU Ze-hua",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,China"
            }
        ],
        "venue": "Geographical Research",
        "year": 2009
    },
    "ufy1nsqM": {
        "id": "ufy1nsqM",
        "title": "Tourists' Perceived Study on the Authenticity of Urban Historical Blocks——Taking Confucius Temple in Nanjing as An Example",
        "abstract": "Study of authenticity has prompted a flurry of concern in domestic tourism science. Authenticity contains not only the genuineness of tourist destinations,but also tourists' perception of the authenticity of destinations. The paper,taking RBD and historical blocks in Nanjing Confucius Temple as an example,studies the \"authenticity\" of scenic area that can satisfy tourists' experience of history and culture and comprehensive demand of their commercial consumption. Then the authors,after conducting factor analysis of tourists' real perception of key scenic spots in Confucius Temple,induce two factors that construct the perception of authenticity:\"ancient sightseeing activity\" and \"shopping leisure activity\" and compare their perceptions of authenticity among local residents,transients and tourists from all parts of the country as well as \"culture-experience type\",\"recreational-type\" and \"comprehensive and mobile-type\" tourists. The results show distinct difference. The investigation indicates that the main motives of tourists to Confucius Temple scenic area include cultural experience and recreational leisure. They have more accurate grasp of the objective authenticity of Confucius Temple,but even if they know not so much ancient architecture remains in Confucius Temple,they still think Confucius Temple is a scenic area that successfully embodies ancient architecture of the Ming and Qing style.",
        "keywords": [
            "tourists",
            "traditional blocks",
            "historical authenticity",
            "Nanjing Confucius Temple"
        ],
        "authors": [
            {
                "name": "LIAO Ren-jing",
                "org": "School of Geographic and Oceanographic and Sciences of Nanjing University,Nanjing ,China"
            },
            {
                "name": "LI Qian",
                "org": "School of Geographic and Oceanographic and Sciences of Nanjing University,Nanjing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "School of Geographic and Oceanographic and Sciences of Nanjing University,Nanjing ,China"
            },
            {
                "name": "LU Shao-jing",
                "org": "School of Geographic and Oceanographic and Sciences of Nanjing University,Nanjing ,China"
            },
            {
                "name": "QI Qiu-yin",
                "org": "School of Geographic and Oceanographic and Sciences of Nanjing University,Nanjing ,China"
            }
        ],
        "venue": "Tourism Tribune",
        "year": 2009
    },
    "ymaaWxnb": {
        "id": "ymaaWxnb",
        "title": "On Environmental Attitudes and Behavior Intention of Tourists in Natural Heritage Site——A Case Study of Jiuzhaigou",
        "abstract": "Based on relevant theories and empirical studies both at home and abroad,the paper,taking Jiuzhaigou as a case,constructs structural equation model(SEM) to explore potential relationship of tourists' environmental attitudes and behavior in natural heritage site.Through exploratory factor analysis,we find that tourists' environmental attitudes can be further categorized into four dimensions,namely,environmental sentiment,environmental responsibility,environmental knowledge and environmental morality.Furthermore,as indicated by the verified factor analysis and SEM,the study analyzes the relationship between tourists' environmental attitudes and environmental behavior intention.The result of model estimation shows that environmental sentiment and environmental knowledge have significant and positive impact on environmental behavior intention,environmental moral exerts little influence on environmental behavior intention,whereas environmental responsibility is not significant.Finally,some theoretical conclusions about model analysis are summarized.",
        "keywords": [
            "tourist environmental attitude",
            "environmental behavior intention",
            "Jiuzhaigou",
            "structural equation model"
        ],
        "authors": [
            {
                "name": "QI Qiu-yin",
                "org": "Department of Land Resources and Tourism Science,Nanjing University,Nanjing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Land Resources and Tourism Science,Nanjing University,Nanjing ,China"
            },
            {
                "name": "YANG Yang",
                "org": "School of Hotel and Tourism Management,Hongkong Polytechnic University,Hongkong ,China"
            },
            {
                "name": "LU Shao-jing",
                "org": "Department of Land Resources and Tourism Science,Nanjing University,Nanjing ,China"
            },
            {
                "name": "ZHANG Hong-lei",
                "org": "Department of Land Resources and Tourism Science,Nanjing University,Nanjing ,China"
            }
        ],
        "venue": "Tourism Tribune",
        "year": 2009
    },
    "y88mfosh": {
        "id": "y88mfosh",
        "title": "Researching the Transformation of Vernacular Architectural Landscape in Tourism Destination Based on the Residents' Perception——Case Study of the Transformation of the Characteristics of the Tibetam Architectural Landscape in Jiuzhaigou",
        "abstract": "The aim of using method of residents' perception on researching vernacular architectural landscape transformation of tourism destination is promoting residents' participating in tourism plan and vernacular architecture protection. Based on the spot answered questionnaires and further interviews in Shuzheng village of Jiuzhaigou,and the software spss,this paper analyzes the perceptive degree of Shuzheng residents to the transformation of the characteristics of their Tibetan architectural landscape. And the factors of these perceptions are also involved in the paper. As indicated in the analysis,the general structure and the harmonization with the nature of building are recognized as the stronger ingredients in residents evaluating the transformations of the characteristics of their Tibetan architectural landscape; the decoration on elevation and indoor,and the function changing are all recognized as a kind of adaptation to the modern life. According to this paper,the general structure and the harmonization with the nature of building,and the correlative perspectives should be regarded as principles and implies in the following planning and designs,no matter of protection or of new developmental projects.",
        "keywords": [
            "protection",
            "perception of local residents",
            "vernacular architectural landscape",
            "Jiuzhaigou",
            "transformation"
        ],
        "authors": [
            {
                "name": "Li Na",
                "org": " School of Art Design,Nanjing University of Finance and Economic,Nanjing ,China"
            },
            {
                "name": "Zhang Jie",
                "org": " Department of Land Resources and Tourism Sciences,Nanjing University,Nanjing ,China"
            }
        ],
        "venue": "Journal of Nanjing Normal University(Natural Science Edition)",
        "year": 2009
    },
    "9rtxeUnD": {
        "id": "9rtxeUnD",
        "title": "The characteristics and dynamical factors of Chinese inbound tourist flow network",
        "abstract": "Tourist flows could be taken as inherent relations among destinations. It is necessary and feasible to analyze the inbound tourist flows from the view of network, and that would be more theoretical and practical significance to tourist flow study. This paper not only defines the notion of tourist flows network in theory, discusses its significance, but constructs an assessment model of tourist flows network, and uses characterization, density, E-I indictor, centralization, cohesive subgroup and core-periphery, which are from the Social Network Analysis, into the analysis of Chinese inbound tourist flow network as well. Then this paper tries to find out the dynamical factors on tourist flows among provinces by using QAP regression and correlation, which are stemmed from SNA too and better than OLS analysis to some extent in matrix analysis. It is concluded that the inbound tourist flow scale presents a decreasing trend from the Eastern, the Western, the Northeast, to the Midland of China. The whole network is loosely organized and unbalanced. Some eastern provinces not only possess higher centralization and structural dominance, but also closely connect with each other. Furthermore some western provinces have become more important in network, and the regional imbalance of inbound tourist flow network has been narrowing. The natural tourism resource, provincial economic position, foreign relation and spatial distance are major constraints to inbound tourist flows, and the numbers of international travel agencies and flights which are representatives of high quality service and top grade, whether they are in the same region or not, contribute to the tourist flow. By doing all of these, this paper aims at offering a new method for inbound tourist flow research and assisting the formulation of tourism policies at national and provincial levels.",
        "keywords": [
            "Chinese inbound tourism",
            "QAP analysis",
            "Social network analysis",
            "Tourist flow network"
        ],
        "authors": [
            {
                "name": "Fajian Liu",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Dongdong Chen",
                "org": "Anhui Broadcasting Movie and Television College(Anhui Broadcasting Movie and Television College),Hefei,China"
            }
        ],
        "venue": "Acta Geographica Sinica",
        "year": 2010
    },
    "9hKb2mQ1": {
        "id": "9hKb2mQ1",
        "title": "SPATIAL PATTERNS OF TOURIST FLOW:PROBLEMS AND PROSPECTS",
        "abstract": "Tourist flow has long been a basic issue of tourism geography.Researches on spatial patterns of tourist flow have been very popular since 1950s.After literature review,the authors classify the spatial pat-terns of tourist flow into three basic theories which are concentric zone theory,centre-periphery theory and spatial diffusion theory.Concentric zone theory stresses on the regular,centripetal and hierarchical structure from the inner zone to the outlying zone.Centre-periphery theory reflects the relationship between the core areas and the peripheral areas from dependence perspective and spatial diffusion theory research the spatial pattern,flowing process of tourist flow from dynamic angle.This paper makes a sketch map from two dimen-sional scales to visualize the basic spatial patterns of tourist flow.One dimensional scale covers a hierarchical ordering which is \"single point dimension,point to point dimension and systematic dimension\".The other di-mensional scale spans a spectrum,which reveals the above three basic spatial patterns of tourist flow from left to right.The research finds that the problems existing in tourism studies which are that(1)there exists confu-sion of \"regional perspective\" for tourist flow and \"individualistic perspective\" for single tourist for a long time.Tourist flow should be studied from regional perspective;(2) definitions of tourist origin and tourist des-tination from regional perspective is confused;(3) \"dual trap\" is existing in a wide range in spatial patterns of tourist flow but scientific analysis of differences in the functional tourist areas(FTA) are absent;(4) unilateral flowing presented in contemporary studies contradicts with the practical bidirectional inter-regional flow;(5) the research on the direction of tourism flow diffusing only adopted the qualitative method,and only provided empirical evaluations on the statistic of tourist flow and tourism phenomenon;(6) few research focus on spa-tial diffusion in the study of tourism spatial pattern,especially for multi-destination travel behavior.",
        "keywords": [
            "spatial pattern",
            "tourist flow",
            "dual trap",
            "directional bias",
            "tourist O-D system"
        ],
        "authors": [
            {
                "name": "ZHONG Shi-en",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing,Jiangsu ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing,Jiangsu ,China"
            },
            {
                "name": "HAN Guo-sheng",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing,Jiangsu ,China"
            },
            {
                "name": "WANG Lan",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing,Jiangsu ,China"
            },
            {
                "name": "ZHANG Hong-lei",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing,Jiangsu ,China"
            }
        ],
        "venue": "Human Geography",
        "year": 2010
    },
    "3ys1OnVe": {
        "id": "3ys1OnVe",
        "title": "The Measure and Transformation of Border Effect of Cross-border Tourism Region Based on Social Network",
        "abstract": "Administrative boundary is one of the main factors of the cross-border tourism region space development.The border effect measure is the important yardstick to define its influence size.With indexes of social networks such as network density and centrality index,the paper constructs two types of measurement indicators which are the whole border effect and the node border effect,and also carries on empirical analysis for Dabie Mountain Tiantangzhai tourist area.The results showed that: ① The whole border effects of cross-provincial tourist areas are greater than that of cross-county tourist areas,the whole border effects on both sides of the same cross-border tourism region are also different;the proportion of significant node organizations of the cross-provincial border effect is higher than the cross-county border effect.And the non-significance nodes mainly concentrate on scenic area management committee,travel agency,scenic area business company and other social organizations.② The border effect depends on the level of administrative boundaries,geographic traffic,tourism development level and maturity differences on both sides of the border,emotional,cognitive and other factors.③ The source force of the cross-border tourist areas shielding effect into bridge effect comes from the symbiotic nature of tourism resources,the willing of stakeholders in the tourism market development,the fundamental force comes from the demand of regional tourism integration,and the corresponding transformation means are introduced.Based on social network the border effect analysis provides a new perspective for the study on cooperation mechanism of the cross-border tourism.",
        "keywords": [
            "social network",
            "Tiantangzhai tourist area",
            "border effect",
            "cross-border tourism region"
        ],
        "authors": [
            {
                "name": "YANG Xiao-zhong",
                "org": " .College of Territorial Resource and Tourism,Anhui Normal University,Wuhu,Anhui ;Department of Land Resources and Tourism Sciences,Nanjing University,Nanjing,Jiangsu "
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Land Resources and Tourism Sciences,Nanjing University,Nanjing,Jiangsu "
            },
            {
                "name": "YE Shu-juan",
                "org": " .College of Territorial Resource and Tourism,Anhui Normal University,Wuhu,Anhui "
            }
        ],
        "venue": "Scientia Geographica Sinica",
        "year": 2010
    },
    "ERoKQm8i": {
        "id": "ERoKQm8i",
        "title": "Cytotoxic chaetoglobosins from the endophyte Chaetomium globosum.",
        "abstract": "Two new alkaloids chaetoglobosins V (1) and W (2), together with the six known congeners 3-8, were isolated through bioassay-guided fractionations from the EtOAc extract of a solid culture of Chaetomium globosum IFB-E041. The structures were elucidated by spectroscopic methods including mainly 1D and 2D NMR techniques. Chaetoglobosin W (2) was unique in its possession of an oxolane ring formed via an oxygen bridge between C-3 and C-6. The isolated fungal metabolites exhibited moderate cytotoxic activities against four human cancer cell lines (KB, K562, MCF-7, and HepG2) with their IC(50) values in a range of 18-30 µg/mL.",
        "keywords": [
            "chaetoglobosin",
            "structure elucidation",
            "cytotoxicity",
            "chaetomiaceae",
            "chaetomium globosum"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Hui Ming Ge",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Rui Hua Jiao",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Jing Li",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Hui Peng",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Yu Rong Wang",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Jun Hua Wu",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Yong Chun Song",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Ren Xiang Tan",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            }
        ],
        "venue": "Planta medica",
        "year": 2010
    },
    "cB5ERRRQ": {
        "id": "cB5ERRRQ",
        "title": "Analysis on the factors effecting tourists' perceptual image to calligraphic landscape scenic——A case study in Diecaishan,Guilin",
        "abstract": "Diecaishan,a scenic concentrated with inscriptions on precipices in Guilin,is chosen as the example in this case study.The tourist's perception to calligraphic landscape is extracted through influence factor analysis and the differences in perceptual image are researched in light of demographics of the tourists. It is found that the tourist gender has obvious difference in perception to factor\"practice and interest\", female is more liable to be infected and has stronger perception to practicing interest than male;the perception to factor\"association and brain development\"is remarkably effected by the educational level received,good-educated tourist has higher perception to the calligraphic landscape appreciation.Perception differences of different-motivated tourists to calligraphic landscape in Diecaishan are contrasted by means of one-way analysis of variance.It is proved that there are obvious differences in perception to factor\"practice and interest\"and factor\"geographic mark\"in different-motivated tourists.",
        "keywords": [
            "perceptual image",
            "calligraphic landscape",
            "effect factor"
        ],
        "authors": [
            {
                "name": "KE Li",
                "org": "Department of Land Resource and Tourism Sciences,Nanjing University,Nanjing,Jiangsu ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Land Resource and Tourism Sciences,Nanjing University,Nanjing,Jiangsu ,China"
            },
            {
                "name": "LI Qian",
                "org": "Department of Land Resource and Tourism Sciences,Nanjing University,Nanjing,Jiangsu ,China"
            }
        ],
        "venue": "Carsologica Sinica",
        "year": 2010
    },
    "oPVZU8Uy": {
        "id": "oPVZU8Uy",
        "title": "The Impact of Regional Cultural Differences on Tourists' Perception of Tourism Destination Image——A Case Study of Tourists' Perception of Prairie Image in Inner Mongolia Autonomous Region",
        "abstract": "In the field of tourism destination image research,scholars have been attaching great importance to the impact of regional cultural differences on tourism destination image.Based on the model of tourism destination image formation,taking the prairie tourism destination of Inner Mongolia as an example and using some quantitative methods such as Principle Component Analysis,One-Way ANOVN Analysis,the paper comparatively analyzes the changes and differences of three components of tourism destination images(cognitive image /affective image /total image) between cultural tourists inside and outside Inner Mongolia Autonomous Region.The following conclusions are obtained:1.The perception of the prairie tourism destination image of both two regional cultural groups is positive and the image plays an active role in tourism market.2.The overall image of cultural group inside autonomous region is higher than that of cultural group outside autonomous region,while the affective image between the two groups is converse.Among the seven dimensions of cognitive image,the perception of most dimensions of cognitive image of cultural group inside the region is higher than that outside the region.3.Regional cultural differences have no significant impact on tourists' perception of prairie tourism destination image.The study is of certain referential value to the impact of cultural differences on destination image inside the same cultural system.",
        "keywords": [
            "tourists",
            "tourism destination image",
            "prairie destination",
            "regional cultural difference"
        ],
        "authors": [
            {
                "name": "WU Tie-hong",
                "org": "Tourism Department,Inner Mongolia University,Huhhot ,China;Department of Land Resources and Tourism Science,Nanjing University,Nanjing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Land Resources and Tourism Science,Nanjing University,Nanjing ,China"
            },
            {
                "name": "LI Wen-jie",
                "org": "Tourism College,Inner Mongolia Normal University,Huhhot ,China"
            }
        ],
        "venue": "Tourism Tribune",
        "year": 2010
    },
    "ph6U8ru7": {
        "id": "ph6U8ru7",
        "title": "The Relationship between Regional Tourism Interrelation and Fractional Structure of Scenic Spots——A Case Study of Sichuan Province,China",
        "abstract": "This paper examines the intensity and direction of tourism economics relationships among the administrative districts in Sichuan Province.All administrative districts of Sichuan can be classified into two zones: strongly and weakly interrelated zones.This paper analyzes the spatial fractional structure of both zones and concludes that it is influenced by the intensity of the relationship among districts.In the strongly interrelated zone,both capacity dimension and information dimension of tourism scenic spots system tend to have a low value,which indicates a relatively balanced distribution of tourism scenic spots.On the other hand,in the weakly interrelated zone,the value of capacity dimension and information dimension of tourism scenic spots system tend to have a higher value.This indicates that the distribution variation of scenic spots is relatively bigger.",
        "keywords": [
            "spatial fractional structure",
            "tourism scenic spots",
            "tourism interrelationship",
            "Sichuan Province"
        ],
        "authors": [
            {
                "name": "YANG Guo-liang",
                "org": "College of Geography and Resources Science,Sichuan Normal University,Chengdu ,Sichuan;The Study Institute of Tourism and City/Rural Plan,Sichuan Normal University,Chengdu ,Sichuan"
            },
            {
                "name": "ZHANG Jie",
                "org": "The Tourism Institute,Nanjing University,Nanjing ,Jiangsu"
            },
            {
                "name": "PENG Wen-fu",
                "org": "The Study Institute of Tourism and City/Rural Plan,Sichuan Normal University,Chengdu ,Sichuan"
            },
            {
                "name": "WU Yan",
                "org": "The Study Institute of Tourism and City/Rural Plan,Sichuan Normal University,Chengdu ,Sichuan"
            },
            {
                "name": "XU Xia",
                "org": "The Study Institute of Tourism and City/Rural Plan,Sichuan Normal University,Chengdu ,Sichuan"
            },
            {
                "name": "WU Gui-shu",
                "org": "College of Geography and Resources Science,Sichuan Normal University,Chengdu ,Sichuan;The Study Institute of Tourism and City/Rural Plan,Sichuan Normal University,Chengdu ,Sichuan"
            }
        ],
        "venue": "Journal of Sichuan Normal University(Natural Science)",
        "year": 2010
    },
    "KZRG4t0R": {
        "id": "KZRG4t0R",
        "title": "Roles and functions of provincial destinations in Chinese inbound tourist flow network",
        "abstract": "The roles and functions of tourism destination are not only determined by the discrepancy of its tourism statistical indicators,but depended on the tourist flows relations among relative destinations as well,and the interactive relationship is vital to all of destinations.By constructing Chinese inbound tourist flow network,this article firstly classifies,compares,and positions the roles and functions of provincial destinations by structural equivalence model which is from the theory of Social Network Analysis.Then it analyzes those functions by the centralization analysis indicators quantitatively.Finally,this article tries to find out which factors and how those factors affect the function models.It is suggested that 31 provincial destinations in China could be divided into four role types,namely,national tourist center,regional tourist hub,common destination and marginal destination.Although there are many differences among every single destination,the same role type has the same centralization indicator characters.Furthermore,the roles and functions in Chinese inbound tourist flow network are largely subject to regional economic development level,tourist facilities,external contact strength etc.Meanwhile the tourism resources and internal traffic convenience have less influence.In brief,by analyzing the structural character of Chinese inbound tourist flow network and positioning the roles and functions of provincial destinations,this article provides some references for guiding the Chinese inbound tourism in every province into coordination and harmony.",
        "keywords": [
            "tourist flow network",
            "roles and functions",
            "provincial destinations",
            "structural equivalence analysis",
            "chinese inbound tourism"
        ],
        "authors": [
            {
                "name": "LIU Fa-jian",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "ZHANG Jin-he",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "CHEN Dong-dong",
                "org": "Anhui Broadcasting Movie and Television College,Hefei ,China"
            }
        ],
        "venue": "Geographical Research",
        "year": 2010
    },
    "XpjFxISo": {
        "id": "XpjFxISo",
        "title": "CLASSIFIED STATISTIC IN CALLIGRAPHIC LANDSCAPE OF KARST CAVES AND DEVELOPMENT OF CAVE TOURISM ——A Case Study of Guilin in Guangxi Province",
        "abstract": "This paper classifies 1659 historical stone sculptures in Guilin and examines the development of cave tourism of Guilin.Firstly,after summing up all the stone sculptures,the attraction degree of show caves is evaluated.Secondly,the contents of stone sculptures are categorized into 6 types,including spot construction,extensive tour,mass tourism,history of spot and folk custom.The characteristics of cave tourism in different dynasties are revealed and analyzed.The sums of stone sculptures in caves in different sight spots reflect the traveling appeal of each spot in history.In Guilin,9 sight spots(Hidden Dragon Cave,Seven-star Cave,Nanxi Hill etc.) obtain about 50 stone sculptures in caves.The sum and the distribution of stone sculptures in Tang,Song,Yuan,Ming as well as The Republic of China can generally describe the tourist behavior features in ancient tourism.The sum of stone sculptures is chosen as the indicator of tourism and the sum of stone sculptures in caves is chosen as the indicator of cave tourism.By comparing the distributions of the two indicators in different dynasties,the authors find that ancient tourist behavior has characteristics of extensive tourism.And after contrasting the distributions of stone sculptures and stone sculptures in caves,they find that extensive tourism in cave tourism shows a higher proportion than it in other types of tourism.The result shows that Tang Dynasty is the first peak in ancient tourism in Guilin.After that,cave tourism in Song Dynasty experiences a significant period when both scenery construction and group tourism reach general maturity and high prosperity.From the Perspectives of tourist experience,tourism at that time reflects rudiment of mass tourism.The summit of scenery construction appears in Ming Dynasty.Meanwhile,based on tourist experience,the cave tourism has recorded a rising trend of progress since Song Dynasty.",
        "keywords": [
            "calligraphy geography",
            "caves",
            "calligraphic landscape",
            "stone sculptures",
            "tourism"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Department of Land Resource and Tourism Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "KE Li",
                "org": "Department of Land Resource and Tourism Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "YU Jin-biao",
                "org": "Department of Land Resource and Tourism Sciences,Nanjing University,Nanjing ,China"
            }
        ],
        "venue": "Human Geography",
        "year": 2010
    },
    "NxaX7OGj": {
        "id": "NxaX7OGj",
        "title": "A STUDY ON THE EVALUATION OF THE ACCESSIBILITY OF A TOURIST DESTINATION FROM THE PERSPECTIVES OF TOURISTS' PERCEPTION——A Case Study of Jiuzhaigou Nature Reserve",
        "abstract": "Accessibility of a tourist attraction plays an important role in the development of tourism industry.Using a case study of Juzhaigou Nature Reserve,this study establishes a quantitative evaluation model of accessibility of tourist destinations.It is generally assumed that accessibility is the convenience of a place to connect to other places.The accessibility of a tourist destination includes two parts.One is the geographical accessibility,which is related to the location and transportation.The other is the tourists'(consumers') accessibility,which is determined by hardware facilities,cultural environment,as well as visitors' behavior.This investigation is based on a survey of 600 visitors in Jiuzhaigou Nature Reserve,which is conducted during April 28th-May 4th(2008).Likert Scaling and SPSS16.0 are adopted in the analysis process.The result indicates that(1) internal transportation system,information accessibility,facilities and services,cultural environment,comfort and health are the main concern of tourists as accessibility in Jiuzhaigou Nature Reserve;(2) from the visitors' perceptional perspectives,the most important factors which influence the accessibility of a tourist destination are internal transportation conditions,medical service,and personal security;(3) tourists are satisfied with the accessibility of Jiuzhaigou Nature Reserve on the whole;(4) tourists' appraisal after tour is better than the one before tour;(5) Jiuzhaigou Nature Reserve still has lots of opportunities to upgrade its accessibility.Therefore,effective tourism marketing program should be conducted to enhance the competitive power.",
        "keywords": [
            "obstacles",
            "Jiuzhaigou",
            "tourist perception",
            "accessibility"
        ],
        "authors": [
            {
                "name": "WANG Lan",
                "org": "1.School of Geographic and Oceanographic Science,Nanjing University,Nanjing ,China "
            },
            {
                "name": "ZHANG Jie",
                "org": "1.School of Geographic and Oceanographic Science,Nanjing University,Nanjing ,China "
            },
            {
                "name": "CAO Jing",
                "org": "1.School of Geographic and Oceanographic Science,Nanjing University,Nanjing ,China "
            },
            {
                "name": "WU Tie-hong",
                "org": "1.School of Geographic and Oceanographic Science,Nanjing University,Nanjing ,China "
            },
            {
                "name": "CAI Yong-shou",
                "org": "2.The Management Office of Jiuzhaigou Landscape Showplace,Zhangzha Town,Jiuzhaigou ,China"
            },
            {
                "name": "YANG Qing-xia",
                "org": "2.The Management Office of Jiuzhaigou Landscape Showplace,Zhangzha Town,Jiuzhaigou ,China"
            }
        ],
        "venue": "Human Geography",
        "year": 2010
    },
    "psAYbSHp": {
        "id": "psAYbSHp",
        "title": "Factors influencing local residents'attitude towards nature conservation in natural tourism destination:a comparative study on China's Jiuzhaigou National Park and UK's New Forest National Park",
        "abstract": "Nature conservation has become an important part of natural tourism destination management,and local residents' attitude towards nature conservation is crucial to the environmental protection and the sustainable tourism development in the destinations.Nevertheless,there has been only little research work on local residents' environmental attitude and their attitude towards nature conservation in destination to the present.This paper was aimed to determine what factors and how they influence local residents' attitude towards nature conservation in natural tourism destination.Taking China's Jiuzhaigou National Park and UK's New Forest National Park as cases,this paper made a comparative quantitative analysis of local residents' demographic features,environmental improvement expectation of tourism development,perception of tourism environmental impact,tourism environment ethics and the relations to their attitude towards nature conservation.Random sampling questionnaire survey was conducted respectively in local communities of the two case study areas in 2008 and 2009.After some statistic analyses of Chi-Square test,Spearman' s rho Correlation,ANOVA and MANOVA with the software of SPSS16.0,this research came to some results as below:(1) As to local residents in natural tourism destination,their attitude towards nature conservation is effected by various factors with obvious difference between the UK and China;(2) demographic features of local residents have no impact on New Forest National Park's residents' attitude towards nature conservation;while gender and possibility of tourism participation do influence local residents' attitude towards nature conservation in Jiuzhaigou National Park:female residents(Chi-Square χ2 = 5.720,P = 0.017) and those who participated in tourism business(Chi-Square χ2 = 7.365,P = 0.007) are more likely to support nature conservation here;(3) As for residents in New Forest National Park,their attitude towards nature conservation is effected by their environment improvement expectation of tourism development(FNF = 2.222,PNF = 0.071 < 0.10) and their tourism environment ethics rather than their perception of tourism environmental impact(FNF = 1.240,PNF = 0.298).Residents who held stronger environmental improvement expectation of tourism development and who are environment protectionism in New Forest National Park are more likely to be nature conservation supporters(FNF = 5.295,PNF = 0.006) ;(4) With reference to local residents in Jiuzhaigou National Park,their environment improvement expectation of tourism development(FJZG =.686,PJZG = 0.563) and tourism environment ethics(FJZG = 0.437,PJZG = 0.648) have no impact on their attitude towards nature conservation,but their perception of tourism environmental impact does influence their attitude towards nature conservation(FJZG = 3.237,PJZG = 0.017 < 0.10).The more negative their perception of tourism environmental impact is,the stronger they hold supportive attitude towards nature conservation there.",
        "keywords": [
            "natural tourism destination",
            "New Forest National Park(NF)",
            "Jiuzhaigou National Park",
            "attitude towards nature conservation"
        ],
        "authors": [
            {
                "name": "CHENG Shaowen",
                "org": " School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,China; School of City and Environmental Science,Huazhong Normal University,Wuhan ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "School of Service Management; School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "XU Feifei",
                "org": "Bournemouth University; School of Service Management,Bournemouth University,BH12 5BB,UK"
            }
        ],
        "venue": "Acta Ecologica Sinica",
        "year": 2010
    },
    "dAXCjcB0": {
        "id": "dAXCjcB0",
        "title": "On the Progress of Foreign Study on Tourism in Peripheral Areas and Its Enlightenment to China",
        "abstract": "With the strengthening of the trend of tourism globalization,outlying areas have been more and more integrated into entire world tourism system.The champaign and undisturbed natural environment conforms to the demand of tourists for \"nature-based travel\".People in outlying areas are longing for the change of their backward state by developing tourism,but congenital defect there has limited the sustainable development.What are the problems confronting their development of tourism? Which impact on economy,society and environment will be produced? Can regional gap be narrowed? Have there been any mature experiences? With these problems in mind,the paper makes retrospect about the concept,characteristics,main themes for development,the existing problems regarding overseas study on tourism in peripheral areas as well as some mature experiences for the realization of sustainable development in the hope of providing some enlightenment for the sustainable development in China,especially in the middle and western regions.",
        "keywords": [
            "periphery",
            "sustainable development",
            "periphery of periphery",
            "peripheral tourism",
            "pleasant periphery"
        ],
        "authors": [
            {
                "name": "ZHONG Shi-en",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "ZHANG Hong-lei",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "KE Li",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "YIN Li-jie",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "LI Qian",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,China"
            }
        ],
        "venue": "Tourism Tribune",
        "year": 2010
    },
    "SaxDYHFD": {
        "id": "SaxDYHFD",
        "title": "A COMPARATIVE STUDY ON IMPACT OF TOURIST FLOWS IN SPECIAL-TERM ON REGIONAL TOURISM STRUCTURE——As Illustrated by Tourist Flows of Beijing,Huangshan and Xi'an in Golden Weeks",
        "abstract": "Public holidays play a key role in Chinese tourism industry,and the present distribution of tourist flow is a very important topic.Three pairs of scenic spots are selected for study: 1) the Imperial Palace and the Badaling Great Wall in Beijing;2) Hua Mountain and the Ancient Villages at Huangshan,Southern An-hui;3) Terra-cotta Warriors and Horses Museum and Hua Mountain near Xi'an.A comparative study is ap-plied to analyze the impact of tourist flows in special-term of regional tourism structure in golden weeks.Af-ter golden week in \"Labor Day\" and \"National Day\",the National Holiday Affairs Office issues reports of tourist flows in some major tourists spots nationwide based on its information system.We can find that the tourist flows of the six scenic spots all have a bell curve in golden weeks;the mean of R index of the spots is between 0.056 and 0.077;the distinction between the two is less than 0.01;and the G index of every spot is less than 0.The result indicates that more tourists visit these spots in the early stage of golden weeks than usu-al.With the similar grade and popularity,the Imperial Palace has the priority to be visited because of its better location compared to the Badaling Great Wall.The absolute G index of the former one is therefore bigger than the other,and the Pearson Correlation Coefficient will reach the highest value if tourist flow of the Impe-rial Palace lagged 1 day behind.The grade,popularity,location,accessibility of tourism facility of destina-tions and the spatial relationship in a same city affect the spatial structure of the tourist origins,choices of scenic spots and tourist route.These factors determine the tendency of spatial and present distribution of tourist flows.Furthermore,it is the response of tourist flow to the structure of regional tourism in golden weeks.",
        "keywords": [
            "tourist flows",
            "golden week",
            "tourism spatial structure"
        ],
        "authors": [
            {
                "name": "LIU Ze-hua",
                "org": "School of Geography and Oceanographic Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "School of Geography and Oceanographic Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "WU Xiao-gen",
                "org": "School of Geography and Oceanographic Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "SHI Chun-yun",
                "org": "School of Urban Environmental Sciences,Xuzhou Normal University,Xuzhou ,China"
            }
        ],
        "venue": "Human Geography",
        "year": 2010
    },
    "gxZt7Mwf": {
        "id": "gxZt7Mwf",
        "title": "Effect of residents' tourism development expectation and tourism impacts perception on their attitude towards tourism in natural tourist destination:A comparative study between China's Jiuzhaigou and the UK's New Forest National Parks",
        "abstract": "Local residents' perception of tourism impacts in tourist destinations has been found to affect their attitude towards tourism;however,there have been relatively few studies on the influence of residents' tourism development expectation on their attitude towards tourism.With the utilization of SPSS16.0 software,this paper,taking China's Jiuzhaigou and the UK's New Forest National Parks as case study areas,makes a comparative study on the influence of local residents' tourism development expectation and touirism impacts perception on their attitude towards tourism.And potentially possible reasons for the influence and the differences between these two cases have been conducted with a qualitative analysis.Some conclusions can be obtained as follows.(1) Local residents' tourism impacts perception,especially tourism benefit perception,directly influences their support of tourism development.(2) Tourism development expectation of local residents directly influences their tourism impacts perception,espetially their tourism benefit perception,and indirectly influences their attitude towards tourism development in the parks via the medium of tourism benefit perception.(3) Residents in both destinations hold positive tourism development expectation with minor differences between the two cases due to cultural differences.Tourism benefit perception of local residents in the two national parks is less and worse than their tourism development expectation,indicating that there is a great gap between their tourism development expectation and tourism impacts perception in these two case study areas.But the majority of local residents in these two parks still hold no negative attitude towards local tourism development in spite of the existing gap.",
        "keywords": [
            "new forest national park",
            "tourism impacts perception",
            "tourism development expectation",
            "jiuzhaigou national park",
            "tourism attitude"
        ],
        "authors": [
            {
                "name": "CHENG Shao-wen",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,China;School of Urban and Environment Science,Huazhong Normal University,Wuhan ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "XU Fei-fei",
                "org": "School of Tourism,Bournemouth University,Bournemouth BH12 5BB,UK"
            },
            {
                "name": "LIANG Yue-lin",
                "org": "School of Management,China University of Geosciences,Wuhan ,China"
            }
        ],
        "venue": "Geographical Research",
        "year": 2010
    },
    "EAXnEY0r": {
        "id": "EAXnEY0r",
        "title": "Research on interactive relationship between terrain cognition and spatial behavior in small-scale environment: A case study of Pukou Campus in Nanjing University",
        "abstract": "Although the interactive relationship between terrain cognition and spatial behavior plays an important role in human-environment relationships, few studies have explored this issue which has been recently paid more attention in behavioral geography. To examine such relationship in daily activities, the Pukou Campus in Nanjing University is chosen as a study area. On the basis of pre-research, the stratified proportional sampling method is used to obtain the samples in the survey of the terrain cognition and spatial behavior respectively, while sketch mapping and verbal description methods are also employed to collect the data. Then the data were analyzed by using the coding method of the geographical elements and attributes, public maps of terrain cognition and spatial behavior, overlay and buffer analysis, bias correlation. Some conclusions can be drawn as follows: (1) The rank orders of elevation cognition of terrain have been coded in subject's cognitive map, and most parts of spatial pattern of terrain in the case area have been recognized. (2) Most major points of campus activities are correlated with requisite activities, while more minor points of campus activities are in relation to spontaneous activities and social activities. The routes of requisite activities which lined the living area and teaching area are straight-line and distributed in south of the campus. Moreover the routes of spontaneous activities which lined more stadium and landscape are scattered in campus. (3) There is interactive relationship between terrain cognition and spatial behavior. The spatial pattern of behavior is influenced by terrain cognition, but such influence is mediated by the motive and cognition of efficiency. The spatial behavior is among the dominant factors of terrain cognition and vise versa, and its effect is mediated by the motive and period of behavior. (4) It is the location of dorm instead of gender and subject that significantly influences the interactive relationship between terrain cognition and spatial behavior. Finally the insufficiency and future direction of research is discussed.",
        "keywords": [
            "Geographical environment cognition",
            "Human-environment relationships",
            "Interactive relationship",
            "Spatial behavior",
            "Terrain cognition",
            "Way finding"
        ],
        "authors": [
            {
                "name": "Zhijie Jiang",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Lili Li",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Shouhong Nie",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            }
        ],
        "venue": "Acta Geographica Sinica",
        "year": 2011
    },
    "lfN9VoON": {
        "id": "lfN9VoON",
        "title": "Analysis of tourism labor's inter-industry mobilty rules based on comparison among five areas at home and abroad",
        "abstract": "Tourism employment has many positive and negative characteristics,which play a particular role in tourism labor's inter-industry mobility under different social backgrounds.Taking Jiuzhaigou as a case study,the article,through a comparative study in the existing work on mobility in Hungary,Somerset and Coventry in the United Kingdom,Jiuhua Mountain in China and Vancouver Island in Canada,analyzes tourism labor's mobility pattern,self-evaluation of mobility impacts,and mobility motivations under different backgrounds.The findings of the study are as follows.First,labor comes from an unusually wide range of industries.In foreign countries,the highest percentage engaged in trade(Wholesale and Retails Trade),and public sector such as public administration,and education and health contributed a high proportion,and mobility from declining industries was not insignificant,approximately accounting for 10%.In China tourism draws labor mainly from the traditional sectors such as agriculture and manufacturing,and high proportion of unemployed and female young labors are inclined to work in tourism.Second,the most positive impact of mobility was reported on the job satisfaction variables.The dominance of job satisfaction and physical environment may have been traded off for poor income,long working hours and job/education match.As is indicated by the multi-regression analysis,the satisfaction is mainly supported by career prospects,living standards,working hours and physical environment in China.Third,factor analysis of 30 motivation variables confirms five-dimensional structure.The means' ranking of motivation and factor display that labor mainly arrives by \"positive\" attributes associated with this industry and few are absorbed for \"refuge\".In China \"instrumental utility\" together with \"positive\" is the strongest motivational forces.\"Entrepreneurial\" is correlated with businessman moving from agriculture and service industry.\"Instrumental utility\" and \"positive\" are most approved by all kinds of samples,but \"refuge\" approved least.These rules result from the combined effort exerted by the three powers of tourism employment's characteristics,regional socio-economic backgrounds and case's features.",
        "keywords": [
            "comparative study",
            "mobility rule",
            "dynamics mechanism",
            "tourism labor"
        ],
        "authors": [
            {
                "name": "YANG Zhao",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,China;College of Territorial Resource and Tourism,Anhui Normal University,Wuhu ,Anhui,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "CAI Yong-shou",
                "org": "The Management Office of Jiuzhaigou Landscape Showplace,Jiuzhaigou ,Sichuan,China"
            },
            {
                "name": "SHANGGUAN Xiao-yan",
                "org": "The Management Office of Jiuzhaigou Landscape Showplace,Jiuzhaigou ,Sichuan,China"
            },
            {
                "name": "HAN Guo-sheng",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,China"
            }
        ],
        "venue": "Geographical Research",
        "year": 2011
    },
    "GtuEmkmH": {
        "id": "GtuEmkmH",
        "title": "Evaluation of Difference in Rural Residents' Conception on Tourism Impact——A Case Study of Tiantangzhai Scenic Spot",
        "abstract": "Based on evaluation of relevant documents on the residents′ perception on tourism impact,there is few study relating to a developing tourism destination at the primary stage.Based on a case study of rural community in Tiantang Zhai scenic spot,Anhui Province,this study aims to explore the effects of relevant independent variable on the rural residents' perceptions of tourism impact.Both in-depth interviews and questionnaire survey were used to collect data,and factor analysis,multivariate analysis of variance(MANOVA),and Mean Test were used to analyze the data.Meanwhie detailed qualitive data helps to provide convicing interpretation and confirmation to the quantitive findings with fully thick description.The findings indicate that there is significant difference in perceived tourism impact among gender,age,members of village committee,and occupation.The gender variable is significantly different between perceived social costs and community satisfaction while the age variable is significantly different between perceived social cost and nature protection.A significant difference exists in the variable of village committee member between social cost and nature protection.There is significant difference in occupation between nature protection and economic expectation.The results may provide insights for rural resident tourism education and nature protection policies.Also it may provide insights for rural resident tourism education and nature protection policies as follows.Firstly,in order to promote the level of satisfaction,all kinds of tourism benefits for the community from the development of tourism industry should be introduced to the female villagers.Secondly,the possible negative effect of tourism should be explained to common young villagers.Thirdly,all kinds of economical opportunities provided by the tourism industry should be introduced to middle-age villagers and villagers whose occupation are not farmer.Fourthly,tremendous opportunities to handle some significant issues in community provided by the development of tourism should be introduced to elderly persons.",
        "keywords": [
            "Tiantangzhai scenic spot",
            "MANOVA",
            "residents` perceived tourism impacts",
            "community-based tourism"
        ],
        "authors": [
            {
                "name": "HAN Guo-sheng",
                "org": "School of Geography Science,Nanjing University,Nanjing,Jiangsu ,China;School of Business Studies, Shandong University at Weihai,Weihai,Shandong ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "School of Geography Science,Nanjing University,Nanjing,Jiangsu ,China"
            },
            {
                "name": "HUANG Yue-wen",
                "org": "School of Management,Shih Hsin University,Taipei,Taiwan 11604,China"
            },
            {
                "name": "YIN Li-jie",
                "org": "School of Geography Science,Nanjing University,Nanjing,Jiangsu ,China"
            }
        ],
        "venue": "Scientia Geographica Sinica",
        "year": 2011
    },
    "XfXl32QE": {
        "id": "XfXl32QE",
        "title": "A reformulated directional bias of tourist flow",
        "abstract": "Conventional directional bias is unable to identify the interactions and relationships between emitted tourist flows and attracted tourist flows, while arguably contradicting the actual emitting/attracting functions for any region, especially in systematic analysis. A newly coined FTR (Functional Tourism Region) based on a regional perspective and a new directional bias derived from conceptual, geographical and technical contexts are proposed. This paper proposes that the new directional bias is defined in terms of two characteristics. The first is the pointing of tourist flow as well as its pointing types, and the second is the inertial state of pointing. Pointing types are classified into three basic types: city-pointing, seaside-pointing and sun-lust-pointing. A case study of Chinese rural residents' domestic overnight travel pattern demonstrates that the new definition of directional bias may yield useful qualitative and quantitative information. Results indicate that city-pointing and seaside-pointing constitute the main pattern, while sun-lust-pointing increasingly contributes to the evolution of the whole tourist flow system. Increasing regional disparity is also detected in that China's eastern economic belt continuously enjoys tourism profits. Finally, it is postulated that the new directional bias of tourist flow can also be applied to other non-work flows that also have origins and destinations. © 2011 Taylor & Francis.",
        "keywords": [
            "china",
            "city-pointing",
            "directional bias",
            "domestic tourism",
            "functional tourism region",
            "rural residents",
            "seaside-pointing",
            "sun-lust-pointing",
            "tourist flow",
            "geography",
            "tourism",
            "profitability"
        ],
        "authors": [
            {
                "name": "Shien Zhong",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Zhang Jie",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Xiang Li",
                "org": "University of South Carolina(University of South Carolina),Columbia,United States"
            }
        ],
        "venue": "Tourism Geographies",
        "year": 2011
    },
    "9LSJzjbr": {
        "id": "9LSJzjbr",
        "title": "Tourism disturbance assessment of Jiuzhaigou Tourism Area based on landscape metrics",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Zhang Jie",
                "org": "2School of Geography and Oceanographic Sciences,Nanjing University,Nanjing 210093,China)"
            }
        ],
        "venue": "Chinese Journal of Ecology",
        "year": 2011
    },
    "bJwf9Rch": {
        "id": "bJwf9Rch",
        "title": "The Characteristics and Impact Mechanism of Region Cooperation in Cross-border Tourism",
        "abstract": "Cross-border tourism region is a special type of tourist destination which has large tourism development potential,complexity of problem and obvious contradiction.Now it becomes a new research focal point in regional tourism development.The study sums up the six characteristics of cross-border tourism region cooperation based on its space attribute,functional attribute,supply and demand attribute,the content of cooperation,border attitude,and organizational attribute.And taking Tiantangzhai of Dabie Mountain,a mountainous resort cross-border tourist region in China,as an example,this study reveals that the influence mechanism of cross-border tourism region cooperation is a complex feedback system with an interaction among macro,medium and micro factors.The macro-view impact factor is the regional level,including regional economic factors,regional socio-cultural factors,regional institutional factors and regional location factors.The medium-view factors is the organizational level,including organizational values and culture,organizational structure,organizational history,organizational systems and organizational networks.And the micro-view factors is individual stakeholders,including the stakeholder values,professional background,personality traits and the awareness,attitudes and behavior to the scenic area development and environmental protection.",
        "keywords": [
            "cross-border cooperation",
            "cross-border tourism region",
            "impact mechanism"
        ],
        "authors": [
            {
                "name": "YANG Xiao-Zhong",
                "org": "College of Territorial Resource and Tourism,Anhui Normal University,Wuhu,Anhui ,China;Department of Land Resources and Tourism Sciences,Nanjing University,Nanjing,Jiangsu ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Land Resources and Tourism Sciences,Nanjing University,Nanjing,Jiangsu ,China"
            },
            {
                "name": "PENG Min",
                "org": "College of Territorial Resource and Tourism,Anhui Normal University,Wuhu,Anhui ,China"
            }
        ],
        "venue": "Scientia Geographica Sinica",
        "year": 2011
    },
    "ueuHizYT": {
        "id": "ueuHizYT",
        "title": "Review of studies on environmental impacts of tourism waste",
        "abstract": "Tourism environmental impact has been a core issue in Tourism studies and its investigation has originated from 1960s abroad while it attracted researcher's attention till early 1980s in China. Although the impacts of tourism development on natural and social environment has been recognized, systematic studies of destination environment and its sustainable development in evaluation models, measure approaches, determinant factors, mechanism, integrative measures and management are still relatively rare. Researchers and policymakers pay much attention to the particular region, but give little consideration to that environmental impact of tourism development has the characteristics of interregional diffusion, spatial shift and worldwide influence of ecological liability. Therefore how to investigate the tourist environmental impact thoroughly and how to realize sustainable development from a broad perspective is a theoretical and empirical issue. This paper gives the definition of tourist wastes from the characters of tourism ecosystem cycle of substances and energy. Based on the abroad related literatures of tourism wastes studies published in recent years. It is found that the relative studies covered a wide range regarding their contents and study areas, including tourism waste of tourism exploitation, tourist and tourist corporation activities. But in China, the studies on the tourism wastes are still on the initial stage. The suitable management system for handling the tourism wastes has not been established in China. Some key issues of tourism waste should be Strengthen the research, such as follows. First, research the concept of tourism waste, type, production process and mechanism. Second, analyze the correlations between tourism waste and socio-economic, cultural life. Third, discuss the recycling use of waste tourism. Fourth, Eco-efficiency of tourism waste. Fifth, CO2 emissions of tourism industry and the global climate change. Sixth, assessment the environmental and ecological impacts of tourism waste. © 2011 IEEE.",
        "keywords": [
            "ecological footprint",
            "environmental impact",
            "review",
            "tourism waste",
            "solids",
            "pollution",
            "recycling"
        ],
        "authors": [
            {
                "name": "Jinhe Zhang",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Honglei Zhang",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Fajian Liu",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            }
        ],
        "venue": "2011 2nd International Conference on Artificial Intelligence, Management Science and Electronic Commerce, AIMSEC 2011 - Proceedings",
        "year": 2011
    },
    "MrmCXxAj": {
        "id": "MrmCXxAj",
        "title": "Neural Network Ensemble for Chinese Inbound Tourism Demand Prediction",
        "abstract": "Accurate prediction of the tourism demand is important for tourism management.The state-of-art methods for predictive modeling used in tourism research include traditional statistical methods,soft computing methods,and artificial intelligence methods.Note that artificial intelligence methods,which were introduced to tourism research in the 1990s,have greatly improved the predictive accuracy of modeling methods.Machine learning is an important area of artificial intelligence,which has been widely recognized as a powerful tool for intelligent data analysis.BP neural network,as one of the traditional machine learning technique,has been widely used to construct predictive model for intelligent data analysis.However,BP neural network suffers from several drawbacks,such as overfitting,difficulties in setting parameters,and local minima problem,and hence the performance of BP neural network is very unstable in practical applications.This paper combines an advanced machine learning paradigm named ensemble learning with BP neural network to build neural network ensemble for tourism demand prediction.This study conducts predictive modeling for tourism demand of three important tourist source countries of US,Britain and Australia for travel to Chinese mainland.The results show that,by combining a number of diverse neural networks,neural network ensemble significantly improves the predictive accuracy over traditional statistical methods and traditional machine learning methods including single BP neural network.Such method provides a better choice for more accurate predictive modeling for tourism demand.",
        "keywords": [
            "inbound tourism demand",
            "tourism demand prediction",
            "machine learning",
            "neural network ensemble"
        ],
        "authors": [
            {
                "name": "ZHANG Chen",
                "org": "Department of Land Resources and Tourism Sciences,Nanjing University,Nanjing,Jiangsu ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Land Resources and Tourism Sciences,Nanjing University,Nanjing,Jiangsu ,China"
            }
        ],
        "venue": "Scientia Geographica Sinica",
        "year": 2011
    },
    "rdk9m6Bf": {
        "id": "rdk9m6Bf",
        "title": "Review on Several Issues of Travel Cost Method in Tourist Resources Valuation",
        "abstract": "Travel Cost Method(TCM) is a revealed preference approach for valuing tourist resources based on observed economic behavior.In TCM research,several problems,including selecting model,measuring travel cost and estimating the demand function,are controversial.Based on the literature review and analysis,this paper discusses the biases in TCM research and puts forward some solutions respectively.After that,the validity,applicability and legality of TCM are discussed and the emphasis and direction of the future research are proposed.The result of literature review shows that: 1) there are six categories of TCM,including ZTCM,TCIA,GTCM,ITCM,HTCM and RUM;2) the following problems,which include endogenous stratification,sampling errors,opportunity cost of time and multi-destination trip during the measurement of travel cost,and multi-colinearity,endogeneity and the choice of function form during the estimation of recreational demand function,may lead to biases in TCM valuation;3) although there are various defects in validity in developing countries,and its applicability and legality are controversial,TCM is still an effective method to measure the recreational value of tourist resources;and 4) the development of TCM should shift gradually from case study to bias analysis and validity test,and then,modification and improvement of the TCM model,especially the combination of the TCM and CVM,should be emphasized to establish and perfect the TCM implementation rules that are suitable to developing countries.",
        "keywords": [
            "Travel Cost Method(TCM)",
            "recreational value",
            "tourist resources",
            "resource economics"
        ],
        "authors": [
            {
                "name": "DONG Xue-wang",
                "org": "School of Tourism & Urban Management,Zhejiang Gongshang University,Hangzhou ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Land Resources and Tourism Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "ZHANG Jin-he",
                "org": "Department of Land Resources and Tourism Sciences,Nanjing University,Nanjing ,China"
            }
        ],
        "venue": "Journal of Natural Resources",
        "year": 2011
    },
    "AF3fvIqn": {
        "id": "AF3fvIqn",
        "title": "Oligostilbenes from Vatica mangachapoi with xanthine oxidase and acetylcholinesterase inhibitory activities",
        "abstract": "Phytochemical examination of the branches and twigs of the tropical plant Vatica mangachapoi resulted in the isolation of three novel oligostilbenes named vaticahainols A-C (1-3) along with seventeen known oligostilbenes (4-20). The structures of the new compounds were elucidated on the basis of extensive spectroscopic data analysis, modified Mosher's method, and quantum chemical computation. All of the isolated phytochemicals were screened for their xanthine oxidase (XO) and acetylcholinesterase (AChE) inhibitory activities. © The Royal Society of Chemistry 2011.",
        "keywords": [],
        "authors": [
            {
                "name": "YanHua Qin",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Jiangtao Cui",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Zhikai Guo",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Nan Jiang",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Renxiang Tan",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Huiming Ge",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            }
        ],
        "venue": "RSC Advances",
        "year": 2011
    },
    "qUw4GteC": {
        "id": "qUw4GteC",
        "title": "Hole-fingering in Playing High Diapason Range of Overtone of Dongxiao and Its Related Cultural Significance",
        "abstract": "Most presented textbooks of introduction to Dongxiao(traditional Chinese vertical flute) playing,usually describe the diapason range of Dongxiao as d1-# f3.In this paper,we provide the hole-fingering patterns with a expended range of d1-d4.From the archeological data and historic records,it reveals that Dongxiao is an aboriginal music instrument.And with analysis on historic records,it hypothesized that in ancient China people might play Dongxiao with wider diapason range than that of the most contemporary textbook of Dongxiao.With the characteristics in history,such as folklore music,acoustic aesthetics,cultural symbolic significance,religion and literature,Dongxiao might be a typical symbol to Chinese ancient and folklore music culture with significant cultural identity.With view of development and succeeding of traditional music and cross-cultural exchange,the development of hole-fingering in playing high diapason range of overtone of Dongxiao provides a large space for the development of Dongxiao culture,while the transformation and the related innovation of the structure of the appearances of Dongxiao could cause the decrease of image authenticity of Dongxiao.So it is profitable to conserve the traditional model of the six-hole Dongxiao for the authenticity and cultural identity of Dongxiao culture.",
        "keywords": [
            "identity",
            "hole-fingering",
            "cultural significance",
            "Dongxiao",
            "high diapason"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Institute of Tourism,Nanjing University,Nanjing ,China"
            }
        ],
        "venue": "Journal of Aesthetic Education",
        "year": 2011
    },
    "3rahKXBW": {
        "id": "3rahKXBW",
        "title": "Bias Analysis and Reliability and Validity Test in Contingent Valuation Method:A Case Study of Assessment of Jiuzhaigou's Recreational Value",
        "abstract": "Contingent valuation method(CVM) is a valuation instrument for public goods on the basis of simulated market.However,its hypothesis arouses suspicions and controversies on its reliability and validity among academics.Combined with the literature review,this paper employs CVM to assess the recreational value of Jiuzhaigou and analyzes the biases in the survey.And finally,we conduct tests on test-retest reliability,content validity and convergent validity.It is found that(1) the recreational values of Jiuzhaigou in 2008 and 2009 are 333 million RMB yuan and 346 million RMB yuan respectively.Compared with other valuation results,these values are significantly lower;(2) the biases in CVM lie both in CVM itself and in the procedures where CVM is carried out.The former problems include hypothetical bias,information bias,protest response bias and strategic bias.The latter ones refer to questionnaire design,definition of population and samples,sampling methodology,and statistical analysis process;(3) the test on test-retest reliability indicates that this study is of high reliability;i.e.the valuation results are of high stability and repeatability;but the tests on content validity and convergent validity suggest low validity of the results and the fact that CVM tends to underestimate the value of tourist resources;(4) the development of CVM should shift gradually from case studies to validity and reliability tests.Thus,we have to establish and perfect the CVM implementation rules,which are suitable for developing countries to ensure validity and reliability of the valuation results.",
        "keywords": [
            "Bias",
            "Contingent valuation method (CVM)",
            "Jiuzhaigou",
            "Reliability",
            "Validity",
            "Value of the tourist resources"
        ],
        "authors": [
            {
                "name": "Xuewang Dong",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Chuanhua Liu",
                "org": "Zhejiang Academy of Agricultural Sciences(Zhejiang Academy of Agricultural Sciences,Zhejiang Academy of Agricultural Science),Hangzhou,China"
            },
            {
                "name": "Min Li",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Shi'En Zhong",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            }
        ],
        "venue": "Acta Geographica Sinica",
        "year": 2011
    },
    "IhV8zWjg": {
        "id": "IhV8zWjg",
        "title": "Research prospect of Internet of Things Geography",
        "abstract": "Due to the development of Internet of Things, which is closely related to a series of geographical questions, this paper explore such new phenomenon of Human Geography, especially the change from Internet era to Internet of Things era, and try to construct the framework of Internet of Things Geography, including: 1. Internet of Things break through time and space isolation between geographical space and virtual space, forming smart geographical space, and building new man-land relationship; 2. Internet of Things profoundly affect Spatial Structure, Product Space, Behavioral Geography, and Urban Geography; 3. Geographical study on derivative phenomenon of Internet of Things such as spatial organization, distribution, and industrial distribution, has guidance value for development strategy of Internet of Thing; 4. Information Geography faces new opportunities; 5. Internet of Things profoundly changes the scale and means of geographical study, providing a more micro and real-time research platform. © 2011 IEEE.",
        "keywords": [
            "framework",
            "information and communication technologies (icts)",
            "information geography",
            "internet of things",
            "behavioral geography",
            "urban geography",
            "geographic information systems",
            "human geography",
            "information and communication technology",
            "economics",
            "product space",
            "spatial organization",
            "internet"
        ],
        "authors": [
            {
                "name": "Zhou, Qilou",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            }
        ],
        "venue": "Proceedings - 2011 19th International Conference on Geoinformatics, Geoinformatics 2011",
        "year": 2011
    },
    "lVAgAtan": {
        "id": "lVAgAtan",
        "title": "Modeling hotel room price with geographically weighted regression",
        "abstract": "Insufficient attention has been given to hotel-room-price attributions and its mechanism in the lodging research field till now. This article examines how site and situation factors differently affect lodging industry and room prices. Comparative analysis of four hedonic price models has been conducted to investigate how these attributions influence room price of Beijing's hotels above star three. Spatial autocorrelation in hotel prices and in hedonic room price equation residuals were analyzed in this research too. Some conclusions can be found and summarized: according to the estimated results, for specific locales, the results expressed in a global model might be inaccurate. The fitting coefficient of geographically weighted regression demonstrates the importance of going beyond the global modeling framework when incorporating geographically weighted regression into hedonic price model. At last, an innovative method for determining the influence of a hotel's attributes at market rates on its’ values, or implicit prices was put forward by the authors.",
        "keywords": [
            "geographically weighted regression",
            "hotel room price",
            "spatial autocorrelation",
            "beijing",
            "hedonic price model",
            "accommodation",
            "hospitality industry",
            "comparative analysis"
        ],
        "authors": [
            {
                "name": "Honglei Zhang",
                "org": "School of Geographic and Oceanographic Sciences, Nanjing University, Nanjing, 210093 Jiangsu, PR China"
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Shaojing Lu",
                "org": "School of Geographic and Oceanographic Sciences, Nanjing University, Nanjing, 210093 Jiangsu, PR China"
            },
            {
                "name": "Shaowen Cheng",
                "org": "School of Urban and Environmental Science, Huazhong Normal University, Wuhan, PR China"
            },
            {
                "name": "Jinhe Zhang",
                "org": "School of Geographic and Oceanographic Sciences, Nanjing University, Nanjing, 210093 Jiangsu, PR China"
            }
        ],
        "venue": "International Journal of Hospitality Management",
        "year": 2011
    },
    "mvjqKZtU": {
        "id": "mvjqKZtU",
        "title": "Tourism disturbance assessment of Jiuzhaigou Tourism Area based on landscape metrics",
        "abstract": "The impact of tourism activity on landscape pattern is an important reflection of tourism disturbance,while landscape metrics are the quantitative indices in reflecting the changes of landscape pattern.In order to evaluate tourism disturbance,this paper selected landscape metrics to construct a tourism disturbance degree index with the consideration of tourism use extent and intensity.The index was then applied to evaluate the tourism disturbance in Jiuzhaigou tourism area.During the evaluation process,QuickBird image of the tourism area was selected,and 3S technology was used in the image interpretation and the tourism area partitioning (sub-areas 1-5).From the sub-area 1 to sub-area 5,the elevation was ascending,and the vertical distance of each sub-area was the same.Then,the tourism disturbance degree of each sub-area was calculated.The results indicated that from sub-area 1 to sub-area 5,the tourism use extent was the same but the tourism use intensity showed a decreasing trend,and thereby,the tourism disturbance degree had an overall decrease.Specifically,the tourism disturbance degree of sub-area 2 was the largest,followed by sub-areas 1 and 3,while those of sub-areas 4 and 5 were the smallest.As to each sub-area,the tourism disturbance degree didn’t have significant relationship with the mean patch fractal dimension,which demonstrated that the tourism disturbance had no significant effects on the land use pattern.",
        "keywords": [
            "landscape metric",
            "tourism disturbance",
            "Jiuzhaigou Tourism Area"
        ],
        "authors": [
            {
                "name": "ZHONG Jing",
                "org": "Business Administration Department,Nanjing University of Finance and Economics,Nanjing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "School of Geography and Oceanographic Sciences,Nanjing University,Nanjing ,China"
            }
        ],
        "venue": "Chinese Journal of Ecology",
        "year": 2011
    },
    "cccuZ9Cv": {
        "id": "cccuZ9Cv",
        "title": "AN ANALYSIS OF THE INTERACTION BETWEEN TOURISTS' COGNITIVE DISTANCE AND THEIR SATISFACTION",
        "abstract": "The term cognitive distance refers to people's beliefs about distances between places in large-scale spaces that are far apart and not visible from each other.The cognitive distance phenomenon suggests that when tourists evaluate the impact of distance on their travel decisions,destinations will be placed in a relatively better or worse situation regarding distance than actually exists.Cognitive distance is an important antecedent of tourism geography because it plays a significant role in destination choice and travel behavior.The purpose of this study was to detect the interaction between tourists' cognitive distance and their satisfaction using a survey data.Researchers found that past experience is important in that tourists learn what features of a holiday are more likely to provide them with satisfactory experiences.The theoretical basis of this study was that distance may be an important factor to tourist's satisfaction and more experienced tourists with higher scores on measures of satisfaction may score marginally lower on measures of cognitive distance.A survey data of Jiuzhaigou was used to examine the interaction between tourists' cognitive distance and their satisfaction.Among all the factors we used,only cognitive distance and travel cost affected tourist's satisfaction at a significant level.The results support that cognitive distance has a positive impact on the tourists' satisfaction;the travel cost of Jiuzhaigou's arrivals also has a positive impact on the satisfaction.In the early stage of tourism activities,the main benefits of tourists are the travel benefits from the origin to the destination.The cognitive distance raised the benefits of tourists,and led to the increase of satisfaction level.Arrivals of Jiuzhaigou National Park had high income level and were more concerned about the quality of travel and tourism product quality.Analysis of variance was used to detect the effect of satisfaction to distance perception in the late stage of tourism activities.The study showed that satisfaction of tourists will significantly affect the cognitive distance estimates,and the cognitive distance decreases as the satisfaction enhancing.",
        "keywords": [
            "ANOVA",
            "satisfaction",
            "ordered Logit model",
            "travel cost",
            "cognitive distance"
        ],
        "authors": [
            {
                "name": "ZHANG Hong-lei",
                "org": "Department of Land Resource and Tourism Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Land Resource and Tourism Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "SHI Chun-yun",
                "org": "School of Urban Environmental Sciences,Xuzhou Normal University,Xuzhou ,China"
            },
            {
                "name": "LIU Ze-hua",
                "org": "Department of Land Resource and Tourism Sciences,Nanjing University,Nanjing ,China"
            }
        ],
        "venue": "Human Geography",
        "year": 2011
    },
    "V1T0qMBG": {
        "id": "V1T0qMBG",
        "title": "Spatial structure of excellent tourism resources in Suzhou, China: A GIS-based approach",
        "abstract": "Scientific analysis of regional tourism resources is an important task of tourism planning. Its spatial distribution has determined the direction of tourism development to a certain extent, thus it is vital to reveal the spatial features of tourism resources by the GIS method, which possesses excellent spatial analysis function. This paper used NNI, mean center, standard distance, and standard deviational ellipse to analysis excellent tourism resources of Suzhou. It comes to the conclusions that :(1) the excellent resources shows clustering pattern totally; (2) Grade 5 human tourism resources exhibited the most clustering in the ancient city of Suzhou, rather than others; (3) this spatial structure both had advantages and disadvantages to Suzhou tourism development. This paper reveals the spatial clustering and spatial distribution of eminent tourism resources in Suzhou, in order to give good advice to the scientific planning and balanced development in future.",
        "keywords": [
            "tourism planning",
            "human tourism resources",
            "regional tourism resources",
            "spatial distribution",
            "suzhou",
            "spatial analysis function",
            "pattern clustering",
            "human resource management",
            "travel industry",
            "geographic information systems",
            "china",
            "clustering analysis",
            "spatial structure",
            "planning",
            "tourism development",
            "tourism resources",
            "gis-based approach",
            "dispersed analysis",
            "spatial features",
            "scientific analysis",
            "standard deviation",
            "cluster analysis",
            "indexation",
            "geographic information system",
            "spatial analysis",
            "cultural differences",
            "indexes"
        ],
        "authors": [
            {
                "name": "Fajian Liu",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Honglei Zhang",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Dongdong Chen",
                "org": "Anhui Broadcasting Movie and Television College(Anhui Broadcasting Movie and Television College),Hefei,China"
            }
        ],
        "venue": "Shanghai",
        "year": 2011
    },
    "4QurzxfM": {
        "id": "4QurzxfM",
        "title": "THE RESEARCH ON THE ROLES OF CALLIGRAPHIC LANDSCAPE IN THE CONSTRUCTION OF TOURIST IMAGE——A Case Study in Forest of Steles,Xi'an",
        "abstract": "Calligraphy is not only a symbol of Chinese culture,but also one of cultural landscape symbols in constructing national identity with its long history,diverse forms,abundant connotation and close relationship with human life.For its considerable aesthetic,historical and cultural value,calligraphy plays an important role in modern tourism industry.Calligraphic landscape,as one of important cultural landscapes,which provides much information for tourists,has a major impact on the perception and behavior of visitors.The proposition of the concept of calligraphic landscape makes it possible that the research of calligraphic geography has material carrier and definite object from geographic perspective.Since 1970s,tourism image research has developed rapidly including two research directions: conceptual research and application research,but there is almost no research about the impact of landscape elements on overall destination tourism image.In this paper,we take Xi'an Beilin Museum for an example to study the relationship between tourism image and calligraphic landscape.Firstly,based on the brief summary of calligraphic landscape,combining the method of factor analysis,calligraphy landscape is divided into three dimensions from the function point of view: the dimension of aesthetic experience function,the dimension of local identity function,and the dimension of behavior oriented function.Secondly,by establishing a structural equation model,the role of calligraphic landscape in constructing tourism image has been researched,hoping to help in the future development of tourism and in tourism planning.The result shows that calligraphic landscape has a positive role on tourism image development.However,different dimensions of calligraphic landscape features have different ways in their functions and also different strength.The dimension of calligraphic landscape`s local identity function`s role to emotion image is significant,however,the effect on perception/ cognitive image is not very significant.",
        "keywords": [
            "tourist image",
            "perception",
            "calligraphic landscape",
            "experience"
        ],
        "authors": [
            {
                "name": "YIN Li-jie",
                "org": "School of Geographic Oceanography Sciences,Nanjing University,Nanjing 10093,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "School of Geographic Oceanography Sciences,Nanjing University,Nanjing 10093,China"
            },
            {
                "name": "ZHANG Hong-lei",
                "org": "School of Geographic Oceanography Sciences,Nanjing University,Nanjing 10093,China"
            },
            {
                "name": "ZHANG Chen",
                "org": "School of Geographic Oceanography Sciences,Nanjing University,Nanjing 10093,China"
            }
        ],
        "venue": "Human Geography",
        "year": 2011
    },
    "QES1T16n": {
        "id": "QES1T16n",
        "title": "The Changes of Domestic Tourist Motivations in Tourism Site of Disaster Area Before and After Earthquake:Case of Jiuzhaigou Before and After \"5.12\" Wenchuan Earthquake",
        "abstract": "Crisis or disaster has increasingly influenced tourism development and tourism demands obviously.Effective tourism marketing has been widely proved to be one of the focusing measurements for tourism market recovery in many destinations which suffered no dramatic tourism attractions or facilities damages by disasters.Then study on influence of certain disaster or crisis on tourists' motivation is very crucial for after-disaster tourism destination management and tourism market recovery after some disasters.Taking China's Jiuzhaigou National Park as a case,the authors conducted some quantitatively comparative analyses of tourists's motivation based on the questionnaire survey data collected in the park before(from April 27th to May 5th,2008) and after(from,May 5th to 10th,2009) the Wenchuan Earthquake on May 12th,2008.And some quantitative analytical methods such as MANOVA analysis has been used to analyze the changes of tourist motivation in the destination.Some research results can be drawn as below: 1) Tourists to Jiuzhaigou were mostly motivated by their desire of \"being close to nuture\" both before and after the quake.It is important to note that nature attraction of the world natural heritage was the main and common pull motivation for both short-haul and long-haul markets before and after the earthquake.On the other hand,the Wenchuan Earthquake did great influence most of the tourists' motivations to visit this park—the importance of pulling motivation declined while that of all pushing motivation but \"for social status\" increased;2) Before the earthquake,tourists' knowledge obtaining motivation(experience new things and learn about other culture) was more important than that of recreation motivation(enjoy life and enjoy tranquility),while it has reversely changed after the shock.The importance of the social and psychological motivations(for social status motivation \"to see famous sights\") decreased after the disaster.3) The attraction of non-core attractions in the destination has experienced distance-decay changes,while the attraction of some core attractions in the park showed no changes with distance before and after the shock.Actually,Jiuzhaigou's tourist market segmentation within central-western China experienced adverse changes.According to the results of MANOVA,there were reverse trends between the midwest(increse) and midwest(decrease) in the change of market share before and after the earthquake.But all of these markets showed no great differences of tourist motivation.It may imply that tourist motivation can play a tiny role in the explaination of the market changes within some adajacent developing regions before and after the quake.Based on previous research conclusion,the authors put forward some differential marketing suggestions for its market recovery.",
        "keywords": [
            "tourism site of disaster area",
            "Jiuzhaigou",
            "Wenchuan Earthquake",
            "tourist motivations",
            "before and after earthquake"
        ],
        "authors": [
            {
                "name": "LI Min",
                "org": "Department of Land Resources and Tourism Sciences,Nanjing University,Nanjing,Jiangsu ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Land Resources and Tourism Sciences,Nanjing University,Nanjing,Jiangsu ,China"
            },
            {
                "name": "ZHONG Shi-en",
                "org": "Department of Land Resources and Tourism Sciences,Nanjing University,Nanjing,Jiangsu ,China"
            },
            {
                "name": "DONG Xue-wang",
                "org": "Department of Land Resources and Tourism Sciences,Nanjing University,Nanjing,Jiangsu ,China"
            },
            {
                "name": "LIU Ze-hua",
                "org": "Department of Land Resources and Tourism Sciences,Nanjing University,Nanjing,Jiangsu ,China"
            },
            {
                "name": "CHENG Shao-wen",
                "org": "School of City and Environment Science,Huazhong Normal University,Wuhan,Hubei ,China"
            }
        ],
        "venue": "Scientia Geographica Sinica",
        "year": 2011
    },
    "zVjZ1cQc": {
        "id": "zVjZ1cQc",
        "title": "A new evaluation model for intangible cultural tourism resources:A case study of the ancient poems in Wujiang,Jiangsu",
        "abstract": "Ancient poems,the intangible cultural tourism resources(ICTR),are used to being neglected in tourism development research.In this paper,we carried on a case study of the ancient poems in Wujiang and proposed a qualitative assessment model and two quantitative evaluation models.We also designed a new method for calculating tourism potential based on psychology.In addition,a comparison of proposed evaluation models was made.",
        "keywords": [
            "marginal diminishing",
            "ancient poems",
            "intangible cultural resources",
            "tourist attractions",
            "evaluation"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,China"
            }
        ],
        "venue": "Journal of Suzhou University of Science and Technology(Natural Science Edition)",
        "year": 2011
    },
    "nRSbsqjH": {
        "id": "nRSbsqjH",
        "title": "Study of Tourist Perception after the Special Natural Disaster: A Case Study of Jiuzhaigou after \"5.12\" Wenchuan Earthquake",
        "abstract": "To know tourists risk perception and impact of disasters on tourist behavior is the first step for post-disaster tourism market recovery and tourism industry relief.This study tried to explore the relationship among tourist risk perceptions,the perception of disaster's impact on destination,tourists satisfaction,and loyalty.Taking the Jiuzhaigou as the case study area,we conducted an on-site questionnaire survey with 572 domestic tourists visiting Jiuzhaigou,a world natural heritage in earthquake-hit area,in nearly one year after the massive\"5.12\"Wenchuan earthquake.Based on a structural equation modeling and analysis, some results can be obtained as follows.(1)The less tourists perceived risk,the less they perceived negative disaster's impact on destination;the less the perceived negative disaster's impact on destination,the higher level of satisfaction with the destination;and the higher the level of tourist satisfaction,the stronger the loyalty to the destination;vice versa.(2)It was not tourists’risk perception level but the perceived impact of disaster on destination had direct influence on tourist satisfaction.The loyalty to the destination was positively related with satisfaction during both post-disaster recovery and normal periods.This investigation also concluded that,except perceived negative disaster's impact on destination,tourists’risk perception,satisfaction and loyalty varied significantly by gender and age.Therefore,the strategic priority should focus on reconstructing the destination safety image and easing tourists’risk perception,especially for women and the youth.Finally,comprehensive management recommendations and suggestions have been put forward and discussed for tourist market recovery of disaster-hit destinations.",
        "keywords": [
            "domestic tourist",
            "risk perceptions",
            "satisfaction",
            "Jiuzhaigou",
            "perception of disasters impacts on tourism",
            "5.12 Wenchuan earthquake"
        ],
        "authors": [
            {
                "name": "LI Min",
                "org": "Department of Land Resources and Tourism Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Land Resources and Tourism Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "DONG Xuewang",
                "org": "Department of Land Resources and Tourism Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "CAI Yongshou",
                "org": "Jiuzhaigou World Heritage Administration,Jiuzhaigou ,Sichuan,China"
            },
            {
                "name": "SHANGGUAN Xiaoyan",
                "org": "Jiuzhaigou World Heritage Administration,Jiuzhaigou ,Sichuan,China"
            }
        ],
        "venue": "Acta Geographica Sinica",
        "year": 2011
    },
    "TZ5SdXHf": {
        "id": "TZ5SdXHf",
        "title": "Impact of Disaster Event on Tourism Destination Image:A Case Study of Jiuzhaigou National Park",
        "abstract": "This paper takes a case study of Jiuzhaigou National Park to analysis the change of images of nature-based tourism destination.Data collected in April 27-May 2,2008(just before the 5.12 Wenchuan earthquake) and May 5-May 9,2009(a year after the earthquake) is compared and analyzed with structural equation model,which provides a new perspective to compare the latent variable.Results show that cognitive image has no significant change for actual tourists,because earthquake did not cause substantial and great damage to Jiuzhaigou and it is already after a year of recovery.However,tourist loyalty shows a marked increase mainly due to the impact of emotion.Additionally,tourists'perception on tourism security and social order is declining,leading to lower cognition in nightlife and entertainment.Hoping this study could be an assistant to management,planning and marketing of tourism destination,especially being a reference to reduce economic,political,natural and other impact and help its recovery.",
        "keywords": [
            "disaster",
            "structural equation modeling",
            "tourism destination image",
            "Jiuzhaigou National Park."
        ],
        "authors": [
            {
                "name": "Dong Xiaoli",
                "org": " Center for Recreation and Tourism Research,College of Urban and Environmental Sciences,Peking University,Beijing ,China; Department of Land Resources and Tourism Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "Zhang Jie",
                "org": " Department of Land Resources and Tourism Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "Wu Bihu",
                "org": " Center for Recreation and Tourism Research,College of Urban and Environmental Sciences,Peking University,Beijing ,China"
            },
            {
                "name": "Jiang Zhijie",
                "org": " Department of Land Resources and Tourism Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "Wu Tiehong",
                "org": " Tourism Department of Humanities College,Inner Mongolia University,Huhhot ,China"
            },
            {
                "name": "Dong Xuewang",
                "org": " Department of Land Resources and Tourism Sciences,Nanjing University,Nanjing ,China"
            }
        ],
        "venue": "Areal Research and Development",
        "year": 2011
    },
    "iAcWGAVL": {
        "id": "iAcWGAVL",
        "title": "A STUDY ON THE RELATIONSHIP BETWEEN TOURISM DESTINATION IMAGE,TOURIST SATISFACTION AND BEHAVIORAL INTENTIONS——A Case Study of Guilin Seven Star Park",
        "abstract": "This paper examines the cognitive components of the destination image and their influence on affective image tourists' satisfaction and behavioral intentions and provides a case study of the Seven Star Park in Guilin.Structural questionnaires are employed in the data collection process,and a 19-item scale for measuring the perceptional cognitive image and a 3-item scale for one-dimensional affective image.480 effective questionnaires are finally used for the following analysis.Firstly,the results of exploratory factor analysis of 19-item cognitive image scale confirm the functional-mixed-psychological continuum in the cognitive image of a destination put forward and modified by some international researchers.The four factors finally obtained as the perspective of resource and environmental,which are that(1) tourists' perception of tourism facility and service is posited as the functional component;(2) tourists' perception of natural resources;(3) historical/cultural environment as mixed component;(4) that of place environment of the destination as a psychological component.Secondly,using structural equation model,this paper analyses the influence of each components of cognitive image on the affective image and the influence of all the components of the tourism destination image on tourists' satisfaction and behavioral intentions.Six hypothesis of the conceptual model put forward on this paper are partially supported by the results,which show that,for the Seven Star Park in Guilin,tourists' perception of the place environment as a psychological component of cognitive image of destination influence significantly on tourists' emotions as the affective image;and the other three factors has a statistical significant influence on tourist satisfaction.",
        "keywords": [
            "satisfaction",
            "tourism destination image",
            "functional-psychological continuum",
            "behaviral intention",
            "Qixing Park"
        ],
        "authors": [
            {
                "name": "LU Shao-jing",
                "org": "Department of Land Resources and Tourism Science,Nanjing University,Nanjing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Land Resources and Tourism Science,Nanjing University,Nanjing ,China"
            },
            {
                "name": "ZHANG Hong-lei",
                "org": "Department of Land Resources and Tourism Science,Nanjing University,Nanjing ,China"
            },
            {
                "name": "ZHANG Jin-he",
                "org": "Department of Land Resources and Tourism Science,Nanjing University,Nanjing ,China"
            },
            {
                "name": "KE Li",
                "org": "Department of Land Resources and Tourism Science,Nanjing University,Nanjing ,China"
            }
        ],
        "venue": "Human Geography",
        "year": 2011
    },
    "MAW4QWPV": {
        "id": "MAW4QWPV",
        "title": "Public Awareness of Calligraphy Landscape, Calligraphy Aesthetic Education and Cultural Inheritance",
        "abstract": "Calligraphy landscape is an important component of calligraphy culture and an important way of implementing calligraphy aesthetic education and calligraphy inheritance. The survey of the public awareness is done from two aspects: one is about the general awareness and the other is about the awareness in special geographic locations. The findings show that the characteristics of geographical awareness in special locations are identical with that of the public awareness and living environment is an important geographical element in calligraphy landscape awareness. The survey also discloses that the degree of awareness is related to a person’s geographical background which suggests that calligraphy aesthetic education and cultural inheritance are conducted not only in the field of pure art but also in the field of everyday life environment.",
        "keywords": [
            "cultural geography",
            "calligraphy landscape",
            "public awareness",
            "aesthetic education",
            "cultural inheritance"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Department of Land Resources and Tourism, Nanjing University, Nanjing , China"
            }
        ],
        "venue": "Journal of Aesthetic Education",
        "year": 2011
    },
    "a5NN5SJz": {
        "id": "a5NN5SJz",
        "title": "The dimensions and characteristics of the perception of Chinese calligraphic landscape",
        "abstract": "Combining the human/natural landscapes with the element of Chinese calligraphy which is characterized by the handwriting of Chinese characters, Chinese calligraphic landscape is an essential part of cultural landscapes. And it is worthy to be taken into consideration when exploring the factors causing the spatial differentiation of places and landscapes. The calligraphic landscape is defined as a portion of geographical space with certain visual characteristics and special sense of place resulted from the layout of assembles of calligraphic works/analogous calligraphic works with a certain scale or visual performance. The basic characteristics of the calligraphic landscape can be explored by the investigation of the perceptual dimensions of the calligraphic landscape. By the open-ended questionnaires, undergraduate students, excluding those who major in calligraphy, from Nanjing University and Nanjing University of Finance, were investigated in April and May in 2004. A total of 496 valid questionnaires were collected finally. After context encoding and weight processing, this article reveals the public perceptual characteristics of Chinese calligraphic landscape. Six perceptual dimensions are concluded as i) perceptual time, ii) geographic environment, iii) calligraphic idiosyncrasy, iv) the calligraphy carrier form, v) value and vi) individual psychology, among which calligraphic idiosyncrasy and geographic environment are the most important factors influencing the perceptual process of calligraphic landscapes. Then this article describes different types and their perceptual characteristics of the settings of calligraphic landscapes. According to the statistical results of perceptual frequency, the settings investigated are divided as three levels as i) the scenic spots thought to be the representative of calligraphic landscape by the public, ii) the place related with the public's normal life where calligraphic landscapes can be perceived more easily if related with exhibition/economy/daily life/culture, and iii) the news media and squares where calligraphic landscapes are believed impossible to present. The result of eye movement analysis indicates the importance of calligraphic landscapes as landmarks during tourists' perception of a scenic spot. On tourism scenic spots, compared with the calligraphic landscapes in the garden, the lake and seaside, those in the mountains, the palace and the temples are more impressive for the public. This research has contributed to the empirical study of Chinese cultural landscape with a valid method.",
        "keywords": [
            "Calligraphic landscape",
            "Cultural geography",
            "Cultural symbol",
            "Perceptual dimensions",
            "Spatial differentiation"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Shaojing Lu",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Zhijie Jiang",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Qi Li",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Li Liang",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Na Li",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Zhengming Huang",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            }
        ],
        "venue": "Acta Geographica Sinica",
        "year": 2012
    },
    "VTiH9kAI": {
        "id": "VTiH9kAI",
        "title": "Spatial Characteristics and Optimition Countermeasures of Chinese City Hotel Industry Efficiency",
        "abstract": "Through the use of DEA model,this paper analyses spatial characteristics and optimization of Chinese city hotel industry efficiency,the result shows:(1) The comprehensive efficiency of Chinese city hotel industry is general level,the number of the pure technical efficiency optimal city is more than the number of comprehensive efficiency of optimal city and scale efficiency of optimal city,and it also discloses the pure technical efficiency is the main influence factors of comprehensive efficiency which is general level.(2) In the aspect of regional characteristics,Chinese city hotel industry comprehensive efficiency show \"the eastern regions higher than the northeast regions,the northeast regions higher than the western regions,the western regions higher than the central regions\"spatial pattern.In the aspect of the classification characteristics,high efficiency,low efficiency and intermediate two types show \"big in the middle and pointed in both ends\" spatial pattern.(3) Chinese city hotel industry input and output indicators generally exist input redundancy and output shortcomings phenomenon,and this paper points out several measures,for example,vigorously the introduction of new technology,improvement the overall quality of employees,adjustment factor input structure and scale,enhancement factor conversion efficiency and promotion asset to recombine and so on,in order to improve the comprehensive efficiency of the city hotel industry in China.",
        "keywords": [
            "spatial characteristics",
            "optimization countermeasures",
            "hotel industry efficiency",
            "city"
        ],
        "authors": [
            {
                "name": "SUN Jing-rong",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,Jiangsu,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,Jiangsu,China"
            },
            {
                "name": "ZHANG Jin-he",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,Jiangsu,China"
            },
            {
                "name": "ZHONG Shi-en",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,Jiangsu,China"
            },
            {
                "name": "MA Jin-hai",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,Jiangsu,China"
            },
            {
                "name": "ZHANG Yu-ling",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,Jiangsu,China"
            }
        ],
        "venue": "Economic Geography",
        "year": 2012
    },
    "ruN58SiU": {
        "id": "ruN58SiU",
        "title": "Analysis of Regional Differences in Response to Crisis Events of China's Inbound Tourism",
        "abstract": "Crisis events occur frequently in last 30 years,and have brought series of negative effects on China's inbound tourism.So,it has a practical sinificance to analyze the regional differences of crisis events impacting.Time series method and coefficient of variation calculation are the main research methods in this research.Annual propotion of regional inbound tourist flows during high probability period of the regional climate disaster or disaster occurred year which are often lower than corresponding national average,whereas the disasters which threating life safety strongly or blocking traffic have a serious impacting on inbound tourism.The inbound tourism is more nonsensitive to the crisis events what the ability to resist crisis events is stronger in the east region,also it's faster to recover after crisis events.Meanwhile,the inbound tourism is more sensitive to the crisis events what the ability to resist crisis events is weaker in the northwest arid area,Tibet Autonomous Region,and Hainan province,also it's slower to recover after crisis events.The inbound tourism of Beijing and Shanghai in the leading position in the country,but it disturbed by crises events vulnerably.Both inbound tourism and domestic tourism are strucked by political events and disease,meanwhile,variety of crisis occured at the same time have impacted inbound tourism seriously.It's clearly that inbound tourism is more sensitive to crisis events compared with domestic tourism.",
        "keywords": [
            "extreme weather and climate events",
            "coefficient of variation",
            "trough",
            "inbound tourism",
            "crisis events"
        ],
        "authors": [
            {
                "name": "ZHANG Yu-ling",
                "org": "Department of Land Resources and Tourism Sciences,Nanjing University,Nanjing ,Jiangsu,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Land Resources and Tourism Sciences,Nanjing University,Nanjing ,Jiangsu,China"
            }
        ],
        "venue": "Economic Geography",
        "year": 2012
    },
    "ApQDO0Ek": {
        "id": "ApQDO0Ek",
        "title": "Mining tourist preferences with twice-learning",
        "abstract": "Data mining techniques have been recognized as powerful tools for predictive modeling tourist decision-making process. However, two practical yet important problems have not been resolved by the data miners in empirical tourism research. Firstly, comprehensibility-the role of the data mining should not only generate accurate predictions, but also provide insights why certain prediction is made. But most widely used data mining methods that can generalize well are black-box in nature and can provide little information on the tourist decision-making facts. Secondly, the lack of training samples-it is usually rather difficult to collect enough training samples through surveying the tourist on site, especially for surveying the tourist's decision-making facts. Many data mining methods may not achieve satisfactory performance if learned on small data set. In this paper, we show that these two problems can be addressed simultaneously using a twice-learning framework on the travel preference data. The results indicate that by addressing these two problems properly, we can predict tourist preferences accurately as well as extracting meaningful insights which would be useful for tourism marketing.",
        "keywords": [
            "predictive modeling tourist decision-making",
            "small data",
            "data mining",
            "tourist decision-making fact",
            "data mining method",
            "decision-making fact",
            "tourist preference",
            "data miner",
            "mining tourist preference",
            "travel preference data",
            "data mining technique"
        ],
        "authors": [
            {
                "name": "Chen Zhang",
                "org": "Department of Land Resources and Tourism Sciences, Nanjing University, Nanjing, China"
            },
            {
                "name": "Jie Zhang",
                "org": "Department of Land Resources and Tourism Sciences, Nanjing University, Nanjing, China"
            }
        ],
        "venue": "Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)",
        "year": 2012
    },
    "a4OORRtj": {
        "id": "a4OORRtj",
        "title": "The Dimensions and Characteristics of the Perception ofChinese Calligraphic Landscape",
        "abstract": "Combining the human/natural landscapes with the element of Chinese calligraphywhich is characterized by the handwriting of Chinese characters,Chinese calligraphiclandscape is an essential part of cultural landscapes.And it is worthy to be taken intoconsideration when exploring the factors causing the spatial differentiation of places andlandscapes.The calligraphic landscape is defined as a portion of geographical space withcertain visual characteristics and special sense of place resulted from the layout of assemblesof calligraphic works/analogous calligraphic works with a certain scale or visual performance.The basic characteristics of the calligraphic landscape can be explored by the investigation ofthe perceptual dimensions of the calligraphic landscape.By the open-ended questionnaires,undergraduate students,excluding those who major in calligraphy,from Nanjing Universityand Nanjing University of Finance,were investigated in April and May in 2004.A total of496 valid questionnaires were collected finally.After context encoding and weight processing,this article reveals the public perceptual characteristics of Chinese calligraphic landscape.Sixperceptual dimensions are concluded as i) perceptual time,ii) geographic environment,iii)calligraphic idiosyncrasy,iv) the calligraphy carrier form,v) value and vi) individualpsychology,among which calligraphic idiosyncrasy and geographic environment are the mostimportant factors influencing the perceptual process of calligraphic landscapes.Then thisarticle describes different types and their perceptual characteristics of the settings ofcalligraphic landscapes.According to the statistical results of perceptual frequency,thesettings investigated are divided as three levels as i) the scenic spots thought to be therepresentative of calligraphic landscape by the public,ii) the place related with the public'snormal life where calligraphic landscapes can be perceived more easily if related withexhibition/economy/daily life/culture,and iii) the news media and squares where calligraphiclandscapes are believed impossible to present.The result of eye movement analysis indicatesthe importance of calligraphic landscapes as landmarks during tourists' perception of a scenicspot.On tourism scenic spots,compared with the calligraphic landscapes in the garden,thelake and seaside,those in the mountains,the palace and the temples are more impressive forthe public.This research has contributed to the empirical study of Chinese cultural landscapewith a valid method.",
        "keywords": [
            "cultural geography",
            "perceptual dimensions",
            "cultural symbol",
            "calligraphic landscape",
            "spatialdifferentiation"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "LU Shaojing",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "JIANG Zhijie",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "LI Qian",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "LIANG Li",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "LI Na",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "HUANG Zhengming",
                "org": "School of Geographic and Oceanographic Sciences,Nanjing University,Nanjing ,China"
            }
        ],
        "venue": "Acta Geographica Sinica",
        "year": 2012
    },
    "xPGBvuQ4": {
        "id": "xPGBvuQ4",
        "title": "A Study on the Behavioral Models of the Business Associations",
        "abstract": "The business associations can be classified into two types: club-type business associations and associations for collective actions. The former mainly provides club-type products for the sake of its members' optimal interests; while the latter is intended to advocate and organize collective actions. The main problem to be solved for the latter is the representativeship for the whole interest group. For mixed-type associations offering both products mentioned above, there must be a compromise between their members' optimal interests and the most universal representativeship.",
        "keywords": [
            "Club-type Product",
            "Free-rider",
            "Public Goods",
            "Business Associations"
        ],
        "authors": [
            {
                "name": "XU Linqing",
                "org": "Department of International Economy and Trade, Jinan University, "
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of International Economy and Trade, Jinan University, "
            }
        ],
        "venue": "Finance & Trade Economics",
        "year": 2007
    },
    "Vs6YC3GH": {
        "id": "Vs6YC3GH",
        "title": "The Sino-US Structural Trade Imbalance:An Analysis Based on Heckscher-Ohlin Model",
        "abstract": "An analysis of Sino-US trade imbalance under the background of new pattern of international labor division shows that the root cause for Sino-US trade imbalance consists in the structural imbalance between service trade and goods trade. The Sino-US trade imbalance impinges on the asymmetry of global trade liberalization in services and goods. Allowing for the slow progress in global trade liberalization in service and the commitment China has made for service trade liberalization, Sino-US trade imbalance will not be extinguished for a long time.",
        "keywords": [
            "trade in service.",
            "international division of labor",
            "comparative advantages",
            "Sino-US trade imbalance"
        ],
        "authors": [
            {
                "name": "ZHENG Hui",
                "org": "College of Economics, Jinan University, Guangzhou ;College of Economics and Management, Southwest University, Chongqing "
            },
            {
                "name": "ZHANG Jie",
                "org": "College of Economics, Jinan University, Guangzhou "
            }
        ],
        "venue": "Finance and Trade Research",
        "year": 2009
    },
    "BKye8cIm": {
        "id": "BKye8cIm",
        "title": "The Basic Characteristics of Business Associations' Governance and the Empirical Evidence in China",
        "abstract": "This paper analyzes the basic characteristics of governance in business associations comparing with the frame of corporate governance.The governance in business associations is typical weak governance, considering the lack of interest-oriented ownership and market pressure caused by the nonprofit character, the diversity of governance objectives,the weakness of incentive mechanism and the mutual governance between the organization and its members.Furthermore,the efficiency of weak governance mainly depends on whether business associations could take good use of their unique social capital to overcome the disadvantages of physical capital and formal rules.We also find the evidence about existence of weak governance through survey of business associations' governance in Guangdong and Zhejiang Province.",
        "keywords": [
            "weak governance",
            "characteristics",
            "business association",
            "governance mechanism"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Jinan University,Guangzhou,Guangdong,,China"
            },
            {
                "name": "ZHANG Yuan-yuan",
                "org": "Jinan University,Guangzhou,Guangdong,,China"
            }
        ],
        "venue": "Economic Management Journal",
        "year": 2009
    },
    "X2xUyGRR": {
        "id": "X2xUyGRR",
        "title": "The Effect of Institutional Climates on FDI of Different Industries:An empirical study of the US overseas FDI",
        "abstract": "The institutional climates of host countries do have an effect on the FDI,while different industries have different institution-intensive.The literatures have not supported whether the institutional climates will have the same effect on different industries.The present paper uses the US overseas FDI data to carry out an empirical study of the effect of the institutional climates on American oversea investment in finance,special science and technology service industries,food and manufacture industries.The research findings indicate that,in finance,special science and technology service industries,the institutional climates make larger effect than in food and manufacture industries.These conclusions make a good suggestion to the transitions of our country,which is about to transfer from the manufacturing economy to the service economy.",
        "keywords": [
            "FDI",
            "institutional climate",
            "institutional distance",
            "institutional-intensive"
        ],
        "authors": [
            {
                "name": "HU Chao",
                "org": "College of International Trade,Jinan University,Jinan,Guangdong,,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "College of Economics,Jinan University,Jinan,Guangdong,,China"
            }
        ],
        "venue": "Journal of Guizhou University(Social Sciences)",
        "year": 2010
    },
    "ZmwWRXJl": {
        "id": "ZmwWRXJl",
        "title": "Analysis on Social Capital and Governance Performance of Trade Associations——Taking Trade Associations in Dongguan Guangdong as Example",
        "abstract": "This paper first presents the theorem that Trade Associations(TAs) Social Capital(SC) consists oftwo parts—the internal and external SC,and then analyzes the approach to accumulate TAs SC.It also presentsthree main factors that affect TAs SC: the member structure and common interest,TA servicing,TA regulating.Basing on TAs data from Dongguan Guangdong,employing factor analysis and regression analysis approach,the paper conducts empirical test to and theoretical explanation on the effect which SC has on the TAs governance performance.Further research and conclusion are given at last.",
        "keywords": [
            "trade associations",
            "social capital",
            "factor analysis",
            "governance"
        ],
        "authors": [
            {
                "name": "SHI Bi-tao",
                "org": "School of Economics,Jinan University,Guangzhou,Guangdong,,China;Dept of Economics and Trade,Dongguan University of Technology,Dongguan,Guangdong,,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "School of Economics,Jinan University,Guangzhou,Guangdong,,China"
            }
        ],
        "venue": "Economic Management Journal",
        "year": 2011
    },
    "RYlDQyvT": {
        "id": "RYlDQyvT",
        "title": "Effect of all-trans-retinoic acid and Vitamin D_3 on chemosensitivity of human lung adenocarcinoma cells",
        "abstract": "Objective:To explore the cell cycle progress,apoptosis and chemosensitive effect of all-trans-retinoic acid(ATRA)and VitaminD3(VD3)on human lung adenocarcinoma cells.Method:MTT colorimetric assay,immunohistochemical method,flow cytometry and RT-PCR were applied to observe the effects induced by ATRA or VD3,as well as ATRA and VD3 on lung adenocarcinoma cells.Results:Incubated with 1 μmol/L ATRA or VD3,A549 cells were more sensitive to 1,10 μg/ml cisplatin,but not to 100 μg/ml cisplatin;A549 cells were inhibited the growth and blocked in the G1 phase;A549 cells were promoted the prognosis,increased the expression of Fas and decreased the expression of Bcl-2.While,incubated with with 0.1,0.01 μmol /L ATRA or VD3,A549 cells had not significant changes.Conclusion:ATRA or VD3 enhances the chemosensitivity of lung adenocarcinoma cells,and the two acting together will better the effect.",
        "keywords": [
            "Cholecalciferol",
            "Lung neoplasms",
            "Tretinoin"
        ],
        "authors": [
            {
                "name": "WANG Ying-tian",
                "org": "Department of Respiratory Diseases"
            },
            {
                "name": "MU Xiao-yan",
                "org": "Department of Respiratory Diseases"
            },
            {
                "name": "JIANG Shu-juan",
                "org": "Department of Respiratory Diseases"
            },
            {
                "name": "ZHANG Jie",
                "org": "Central Laboratory,Shandong Provincial Hospital,Shandong University,Jinan ,Shandong,China"
            },
            {
                "name": "ZHANG Xian-xin",
                "org": "Department of Respiratory Diseases"
            },
            {
                "name": "LI Huai-chen",
                "org": "Department of Respiratory Diseases"
            }
        ],
        "venue": "Journal of Shandong Univenity(Health Scicnes)",
        "year": 2005
    },
    "vQlSLkth": {
        "id": "vQlSLkth",
        "title": "Seperation and culture of hepatic stellate cells and Kupffer cells simultaneously",
        "abstract": "Objective:To establish a method for separation and culture of hepatic stellate cells(HSCs)and Kupffer cells(KCs)simultaneously.Method:Non-parenchymal cells were fractionated by sequential collagenase and pronase digestion of liver.HSCs and KCs were separated by 18%(W/V)Nycodenz.HSCs presented themselves at the boundary,while KCs presented themselves below the boundary.Viability of HSCs and KCs was measured by the Trypan blue exclusion test.HSCs were established by the visualization of desmin with anti-desmin antibody by immunocytochemistry staining.KCs were established by the visualization of lysozyme by immunocytochemistry staining.Results:Purity of these cultures was about 95%.This method for cell isolation resulted in a yield of(3.0±0.5)×107 HSCs and(4.0±0.5)×106 KCs per liver.Conclusion:HSCs and KCs can be separated by one-step density gradient centrifugation with nycodenz.",
        "keywords": [
            "Rats",
            "Kupffer cells",
            "Astrocytes",
            "Centrifugation density gradient"
        ],
        "authors": [
            {
                "name": "SHI Jun",
                "org": "Center for Liver Diseases,Shandong Provincial Hospital,Jinan ,Shandong,China"
            },
            {
                "name": "REN Wan-hua",
                "org": "Center for Liver Diseases,Shandong Provincial Hospital,Jinan ,Shandong,China"
            },
            {
                "name": "HAO Jing-hua",
                "org": "Center for Liver Diseases,Shandong Provincial Hospital,Jinan ,Shandong,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Center for Liver Diseases,Shandong Provincial Hospital,Jinan ,Shandong,China"
            },
            {
                "name": "ZHU Ju-ren",
                "org": "Center for Liver Diseases,Shandong Provincial Hospital,Jinan ,Shandong,China"
            }
        ],
        "venue": "Journal of Shandong Univenity(Health Scicnes)",
        "year": 2005
    },
    "zZ5lRp58": {
        "id": "zZ5lRp58",
        "title": "Cloning and expression of human interleukin-26 in Escherichia coli]",
        "abstract": "To clone human interleukin-26 (hIL-26) and express it in E. coli efficiently. Two pairs of primers were synthesized according to the hIL-26 gene reported on GenBank. The hIL-26 gene was cloned by nest PCR following the first round RT-PCR from human peripherial blood monocytes total RNA, and then the PCR product was cloned into pMD18-T vector. Colony PCR, restriction analysis and sequence analysis showed that the gene cloned was the same as the reported hIL-26. The recombinant was cut with BamHI and EcoR I to obtain the hIL-26 fragment, and then the fragment was inserted into pBV220 which was cut with the same enzymes. The recombinant expression vector was induced to express hIL-26 at 42 degrees C, SDS-PAGE analysis showed that the recombinant protein accounted for up to 20% of the whole protein of E. coli, and the protein was also confirmed by Western blotting. Purity of the protein was found to be above 90% after purified with molecular sieve. After renaturalized with glutathione buffer, the promoting effect of it on the production of IFN-y in PBMC was detected by RT-PCR. A recombinant bacterial strain for expressing hIL-26 with biological activity was constructed successfully.",
        "keywords": [
            "cloning and expression",
            "interleukin-26",
            "escherichia coli",
            "biological activity",
            "enzyme",
            "recombinant protein",
            "sequence analysis",
            "nested pcr",
            "interleukin 26",
            "glutathione",
            "molecular sieve"
        ],
        "authors": [
            {
                "name": "Yi-Qing Liu",
                "org": "Institute of Basic Medicine, Shandong Academy of Medical Sciences, Ji'nan 250062, China"
            },
            {
                "name": "Zi-Jiang Chen",
                "org": "Medical Research Center, Shandong Provincial Hospital, Shandong University, Ji'nan 250021, China"
            },
            {
                "name": "Xue Zhang",
                "org": "Medical Research Center, Shandong Provincial Hospital, Shandong University, Ji'nan 250021, China"
            },
            {
                "name": "Lai-Cheng Wang",
                "org": "Medical Research Center, Shandong Provincial Hospital, Shandong University, Ji'nan 250021, China"
            },
            {
                "name": "Yu-Lian Jiao",
                "org": "Medical Research Center, Shandong Provincial Hospital, Shandong University, Ji'nan 250021, China"
            },
            {
                "name": "Jie Zhang",
                "org": "Medical Research Center, Shandong Provincial Hospital, Shandong University, Ji'nan 250021, China"
            },
            {
                "name": "Chun-Yan Ma",
                "org": "Medical Research Center, Shandong Provincial Hospital, Shandong University, Ji'nan 250021, China"
            },
            {
                "name": "Bin Cui",
                "org": "Medical Research Center, Shandong Provincial Hospital, Shandong University, Ji'nan 250021, China"
            },
            {
                "name": "Xin-Pu Gao",
                "org": "Medical Research Center, Shandong Provincial Hospital, Shandong University, Ji'nan 250021, China"
            },
            {
                "name": "Zheng-Min Liu",
                "org": "Medical Research Center, Shandong Provincial Hospital, Shandong University, Ji'nan 250021, China"
            },
            {
                "name": "Kan Wu",
                "org": "Medical Research Center, Shandong Provincial Hospital, Shandong University, Ji'nan 250021, China"
            },
            {
                "name": "Yue-Ran Zhao",
                "org": " Medical Research Center, Shandong Provincial Hospital, Shandong University, Jinan , China; Institute of Basic Medicine, Shandong Academy of Medical Sciences, Jinan , China"
            }
        ],
        "venue": "Sheng wu gong cheng xue bao = Chinese journal of biotechnology",
        "year": 2006
    },
    "4ZBV0bWC": {
        "id": "4ZBV0bWC",
        "title": "Effect of mifepristone on cell cycle arrest and its regulators in prostate cancer cell line PC-3",
        "abstract": "Objective To investigate the effects of mifepristone ( MIF) on cell cycle arrest and its regulating proteins in androgen-independent prostate cancer cell line PC-3. Methods The A values of the prostate cancer cells PC-3 in each group with various concentrations (1 ,10,50 and 100μmol/L) of MIF at different time intervals (24 - 120 h) were detected with MTT assay. 0.1% ethanol was used in controls. The cell cycles of the PC-3 cells treated with 10 and 50μmol/L of MIF for 48 h were assessed by flow cytometry (FCM) analysis. Immunohistochemical and Western blot methods were used to determine the expression of cyclin D1 ,bax and bcl-2 proteins after treatment with 10 and 50μmol/L of MIF. Results The A values of the cancer cells treated with 1μmol/L of MIF were similar to that of controls( P > 0. 05) , while those of the cells treated with 10,50μmol/L and 100μmol/L of MIF were significantly different from that of controls (P <0. 01). MIF markedly inhibited cell proliferation of prostate cancer cells PC-3 in a dose- and time-dependent manner. FCM analysis showed the cell cycle of cancer cells treated with 10 and 50μmol/L of MIF for 48h were blocked at G1/G0 phase,at which the cell ratio increased from 27.4% (controls) to 50.4% (10μmol/L MIF group) and 59.2% (50μmol/L MIF group) ,showing significant difference between the treatment groups and controls(P <0.05). Immunohistochemistry showed the bcl-2 expression decreased from 3.53±0.47 (controls) to 2. 03±0.74 and 1.83±0.44 in the cells treated with 10 and 50μmol/L of MIF, which was significantly different from that of controls (P < 0. 05) ; the expression of cyclin D1 in the cells treated with 10 and 50μmol/L of MIF were significantly decreased to 2. 66±0. 79 and 1. 74±0. 56, as compared with controls(4. 27±0. 98) (P < 0. 05 ) ; and the expression of bax increased from 1. 88±0. 50 (controls) to 2.62±0. 36 ( 10μmol/L MIF group) and 3. 78±0. 31 (50μmol/L MIF group). Western blot analysis revealed the ratio of cyclin D1/β-actin decreased from 0. 82±0. 15(controls) to 0. 57±0. 09 (10μmol/L MIF group) and0.42±0.13 (50μmol/L MIF group) ( P <0. 05 ). The ratio of bcl-2/β-actin in the cells treated with 10 and 50μmol/L of MIF significantly decreased to 0. 59±0. 09 and 0. 47±0. 09, compared with that of controls (0.78±0. 13 ) ( P < 0. 05). However, the ratio of bax/β-actin of 50μmol/L MIF group (0.74±0.11) significantly increased( P <0. 01 ) , while the ratio of bax/β-actin of 10μmol/L MIF group (0.63±0.09) was similar to that of controls (0.51±0. 10). Conclusions MIF can inhibit proliferation of androgen-independent prostate cancer cell line PC-3 in time- and dose-dependent manner. The inhibiting effect is through decreasing cyclin D1 protein expression, which blocks cell cycle progression in G1/G0 phase,and through down-regulating bcl-2 and increasing bax protein expression.",
        "keywords": [
            "Apoptosis",
            "Prostatic neoplasms",
            "Androgen-independent",
            "Mifepristone"
        ],
        "authors": [
            {
                "name": "ZHANG Hui",
                "org": ",L%%#?%%# Jia-ju. Department of Urology, Shandong Provincial Hospital, Shandong University,Jinan ,China"
            },
            {
                "name": "GAO Qing-zhen",
                "org": ",L%%#?%%# Jia-ju. Department of Urology, Shandong Provincial Hospital, Shandong University,Jinan ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": ",L%%#?%%# Jia-ju. Department of Urology, Shandong Provincial Hospital, Shandong University,Jinan ,China"
            },
            {
                "name": "ZHAO Yue-ran",
                "org": ",L%%#?%%# Jia-ju. Department of Urology, Shandong Provincial Hospital, Shandong University,Jinan ,China"
            }
        ],
        "venue": "Chinese Journal of Urology",
        "year": 2006
    },
    "FtmXtSos": {
        "id": "FtmXtSos",
        "title": "Association between polymorphisms of killer cell immunogloblin-like receptor gene and ankylosing spondylitis",
        "abstract": "Objective: To investigate whether the polymorphisms of killer cell immunoglublin-like receptor(KIR) gene has relation with the ankylosing spondylitis(AS).Methods: Polymerase chain reaction-sequence-specific primers(PCR-SSP) method was employed for genotyping KIRs from genomic DNA of 86 AS patients and 412 healthy donors.Results: Gene frequencies of KIR3DS1(P=0.044),KIR2DL2(P=0) and KIR2DL5(P=0.01)were statistically significant higher in the patient group than in the control group.Moreover,the percentage of patients carrying two or more activating KIRs was higher than that of controls.The frequencies of the other KIR loci subjected to assay in this work showed no significant difference in patients and controls.Conclusion: The data from this study suggest that the imbalance of KIR genes may have an association with a genetic predisposition to ankylosing spondylitis.",
        "keywords": [
            "Immunogloblin-like",
            "Genotyping",
            "Spondylitis ankylosing",
            "Receptors",
            "Killer cells"
        ],
        "authors": [
            {
                "name": "JIAO Yu-lian",
                "org": "Medical Research Centre,Shandong Provincial Hospital,Shandong University,Jinan ,Shandong,China;Institute of Basic Medicine,Shandong Academy of Medical Sciences,Jinan ,Shandong,China"
            },
            {
                "name": "MA Chun-yan",
                "org": "Medical Research Centre,Shandong Provincial Hospital,Shandong University,Jinan ,Shandong,China"
            },
            {
                "name": "CUI Bin",
                "org": "Medical Research Centre,Shandong Provincial Hospital,Shandong University,Jinan ,Shandong,China"
            },
            {
                "name": "WANG Lai-cheng",
                "org": "Medical Research Centre,Shandong Provincial Hospital,Shandong University,Jinan ,Shandong,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Medical Research Centre,Shandong Provincial Hospital,Shandong University,Jinan ,Shandong,China"
            },
            {
                "name": "LIU Yi-qing",
                "org": "Medical Research Centre,Shandong Provincial Hospital,Shandong University,Jinan ,Shandong,China"
            },
            {
                "name": "ZHANG Xue",
                "org": "Medical Research Centre,Shandong Provincial Hospital,Shandong University,Jinan ,Shandong,China"
            },
            {
                "name": "CHEN Zi-jiang",
                "org": "Medical Research Centre,Shandong Provincial Hospital,Shandong University,Jinan ,Shandong,China"
            },
            {
                "name": "ZHAO Yue-ran",
                "org": "Medical Research Centre,Shandong Provincial Hospital,Shandong University,Jinan ,Shandong,China;Institute of Basic Medicine,Shandong Academy of Medical Sciences,Jinan ,Shandong,China"
            }
        ],
        "venue": "Journal of Shandong University(Health Sciences)",
        "year": 2006
    },
    "JjGRABJw": {
        "id": "JjGRABJw",
        "title": "Cloning of human interleukin-26 and constructing of its eukaryotic expression vector",
        "abstract": "Objective: To clone the gene of human interleukin-26(hIL-26)and to construct its eukaryotic expression vector.Methods: Total RNA was extracted from the human peripheral blood monocytes,and reverse transcriptase-polymerase chain reaction(RT-PCR)was performed.The PCR product was inserted into cloning vector pMD18-T to construct the recombinant plasmid of hIL-26——pMD18-T/hIL-26.Recombinants were transformed into E.coli-DH5α and screened with colony PCR and restriction analysis.The gene of hIL-26 cloned was sequenced.The hIL-26 gene fragment obtained from pMD18-T/hIL-26 was digested with SalⅠ and EcoRⅠ,and then inserted into pIRES2-EGFP that was cut with XhoⅠ and EcoRⅠ.Recombinants were identified by colony PCR and restriction analysis.The recombinant expression plasmid pIRES2-EGFP-hIL26 was transfected into COS7 cells mediated via nonliposomaltransfection reagent Fugene 6.Results: The sequence of the cloned DNA fragment was identical to hIL-26 that was reported on GenBank,and hIL-26 gene was inserted into eukaryotic expression vector pIRES2-EGFP correctly.The recombinant expression plasmid was successfully transfected into COS7 cells observed by fluorescent microscope and effective expression of hIL-26 was also testified by Western blotting.Conclusion: The recombinant eukaryotic expression vector of hIL26 is successfully constructed and effectively expressed in eukaryotic cells.",
        "keywords": [
            "Eukaryotic expression vector",
            "Gene cloning",
            "Interleukin-26",
            "COS7 cells"
        ],
        "authors": [
            {
                "name": "LIU Yi-qing",
                "org": "Institute of Basic Medicine,Shandong Academy of Medical Sciences,Jinan ,Shandong,China;Medical Research Center,Shandong Provincial Hospital,Shandong University,Jinan ,Shandong,China"
            },
            {
                "name": "WANG Lai-cheng",
                "org": "Medical Research Center,Shandong Provincial Hospital,Shandong University,Jinan ,Shandong,China"
            },
            {
                "name": "JIAO Yu-lian",
                "org": "Medical Research Center,Shandong Provincial Hospital,Shandong University,Jinan ,Shandong,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Medical Research Center,Shandong Provincial Hospital,Shandong University,Jinan ,Shandong,China"
            },
            {
                "name": "MA Chun-yan",
                "org": "Medical Research Center,Shandong Provincial Hospital,Shandong University,Jinan ,Shandong,China"
            },
            {
                "name": "CUI Bin",
                "org": "Medical Research Center,Shandong Provincial Hospital,Shandong University,Jinan ,Shandong,China"
            },
            {
                "name": "GAO Xin-pu",
                "org": "Medical Research Center,Shandong Provincial Hospital,Shandong University,Jinan ,Shandong,China"
            },
            {
                "name": "LIU Zheng-min",
                "org": "Medical Research Center,Shandong Provincial Hospital,Shandong University,Jinan ,Shandong,China"
            },
            {
                "name": "ZHANG Xue",
                "org": "Medical Research Center,Shandong Provincial Hospital,Shandong University,Jinan ,Shandong,China"
            },
            {
                "name": "ZHAO Yue-ran",
                "org": "Institute of Basic Medicine,Shandong Academy of Medical Sciences,Jinan ,Shandong,China;Medical Research Center,Shandong Provincial Hospital,Shandong University,Jinan ,Shandong,China"
            }
        ],
        "venue": "Journal of Shandong University(Health Sciences)",
        "year": 2006
    },
    "s2cvjdos": {
        "id": "s2cvjdos",
        "title": "Effects of heparin on proliferation and incretion of hepatic stellate cells in fibrotic rats",
        "abstract": "[Objective] To evaluate the effects of heparin on the proliferation and secretion of hepatic stellate cells (HSCs),and explore the mechanism. [Methods] HSCs were isolated by one-step density gradient centrifuge with nycodenz and divided into 3 groups. A and B group were given 1 000 μg/ml and 2 000 μg/ml heparin respectively. HSCs proliferation was detected by MTT colorimetric assay.The expressions of α-smooth muscle actin(α-SMA),transforming growth factor-beta 1 (TGF-β_1) and laminin (LN) were measured with immunocytochemistry. [Results] The OD values of HSCs in A,B and C group were 0.0626±0.0137,0.0746± 0.0131 and 0.1106±0.0198,respectively. The OD value of HSCs in A and B group was lower than that in C group significantly (P<0.05) ,and the OD value of HSCs in B group was lower than that in A group.The expression of α-SMA,TGF-β_1 and LN in HSCs of A and B group was weaker than that in HSCs of group C. [Conclusion] Heparin can inhibit the proliferation of HSCs and the collagen synthesis,it may be related with the inhibition of TGF-β_1 expression in HSCs.",
        "keywords": [
            "actins",
            "heparin",
            "hepatic stellate cells"
        ],
        "authors": [
            {
                "name": "SHI Jun",
                "org": "Shandong Provincial Hospital,Jinan ,P.R.China"
            },
            {
                "name": "MA Jin-cai",
                "org": "Shandong Provincial Hospital,Jinan ,P.R.China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Shandong Provincial Hospital,Jinan ,P.R.China"
            },
            {
                "name": "REN Wan-hua",
                "org": "Shandong Provincial Hospital,Jinan ,P.R.China"
            },
            {
                "name": "ZHU Ju-ren",
                "org": "Shandong Provincial Hospital,Jinan ,P.R.China"
            }
        ],
        "venue": "Shandong Medical Journal",
        "year": 2006
    },
    "WLGmtVWJ": {
        "id": "WLGmtVWJ",
        "title": "Inhibition of polypeptide extract from scorpion venom(PESV) against proliferation of Prostate cancer androgen-independent cell lines in vitro",
        "abstract": "Aim To study the effects of PESV on the growth and proliferation of androgen-independent human prostate cancer line DU-145 and PC-3.Methods Cell growth inhibition rate was determined using MTT;cell cycle distribution was analysed using flow cytometry(FCM); cyclin E and p27 expression in protein level was detected using immunohistochemistry.Result PESV(dose range:40~200 mg·L -1)inhibited the growth of PC-3 in a dose-depended matter(inhibiting rate(IR)of DU-145 and PC-3 cell lines with PESV(40 mg·L -1)treatment was 30.5% and 33.1%,P<0.05,vs control,100% with 200 mg·L -1 treatment).FCM analysis showed that PESV arrested the cell cycle mainly in G_1-phase,and cells at G_0/G_1 and G_2/M phase clearly increased. Immunohistochemistry showed PESV downregulate cyclin E(grey analysis, P<0.01 vs control) and upregulated p27 expression (grey analysis, P<0.05 vs control) at protein level Conclusion PESV can inhibit PC-3 and DU-145 growth and proliferation in vitro and may play an important role in prostate cancer therapy",
        "keywords": [
            "PESV",
            "Proliferation",
            "Prostate cancer cells"
        ],
        "authors": [
            {
                "name": "WANG Zhao-peng",
                "org": "Dept of Pathology ,Institute of Basic Medcine,Shandong Academy of Medical Science,Jinan ,China"
            },
            {
                "name": "ZHANG Wei-dong",
                "org": "Dept of Pathology ,Institute of Basic Medcine,Shandong Academy of Medical Science,Jinan ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Dept of Central Laboratory,Shandong Provincial Hospital,Jinan ,China"
            },
            {
                "name": "JIA Qing",
                "org": "Dept of Pathology ,Institute of Basic Medcine,Shandong Academy of Medical Science,Jinan ,China"
            },
            {
                "name": "SONG Shou-qin",
                "org": "Dept of Pathology ,Institute of Basic Medcine,Shandong Academy of Medical Science,Jinan ,China"
            },
            {
                "name": "WANG Zhao-xia",
                "org": "Dept of Pathology ,Institute of Basic Medcine,Shandong Academy of Medical Science,Jinan ,China"
            },
            {
                "name": "HUANG Shan-ying",
                "org": "Dept of Pathology ,Institute of Basic Medcine,Shandong Academy of Medical Science,Jinan ,China"
            },
            {
                "name": "ZHANG Yue-ying",
                "org": "Dept of Pathology ,Institute of Basic Medcine,Shandong Academy of Medical Science,Jinan ,China"
            }
        ],
        "venue": "Chinese Pharmacological Bulletin",
        "year": 2006
    },
    "WgIi0J77": {
        "id": "WgIi0J77",
        "title": "Cilostazol down-regulates intercellular adhesion molecule-1 expression in kidney in streptozocin-induced diabetic rats",
        "abstract": "Objective: To investigate the effect of cilostazol on intercellular adhesion molecule-1(ICAM-1) in kidney of diabetic rats and the protective effect of cilostazol on diabetic kidney.Methods: The diabetic model of male SD rat was prepared by streptozocin(STZ) intraperitoneally.There were 4 groups: normal control group(n=10),diabetic control group(n=15),high-dose of cilostazol group(n=15,25 mg·kg-1·d-1) and low-dose of cilostazol group(n=15,18 mg·kg-1·d-1).Treatment for 12 weeks,all animals were sacrificed.The fasting blood glucose(BG),HbA1c,the ratio of kidney weight to body weight were measured;the ICAM-1 mRNA level of kindey was semi-quantitated by RT-PCR;the expression of ICAM-1 protein of kidney was detected by western blot;the ICAM-1 location tested by immunofluorescence.Results: The levels of BG and HbA1c in diabetic control group were higher than those in normal control group(P<0.05).Compared with diabetic group,the levels of BG and HbA1c did not decrease significantly in both cilostazol treatment groups.Compared with normal control group,the ratio of kidney weight to body weight significantly increased in diabetic control group(P<0.01)and Cilostazol treatment groups(P<0.01).The expression of renal ICAM-1 mRNA in diabeteic control group was significant higher than that in other groups,but showed a down-regulation in cilostazol groups(P<0.01).By immunofluoescence,ICAM-1 staining in diabetic group was strong and located at fargoing kidney tissues,but was weak and located within limits in diabetic animals with cilostazol treatmeat.By western blotting,expression of ICAM-1 protein of kidney was weak in normal control group,increased significantly in diabetic control group,and had a tendency to decrease after the treatment with cilostazol.Conclusion: The expression of ICAM-1 increases in kidney of the STZ-induced SD diabetic rat.Cilostazol can protect the kidney by decreasing the expression of ICAM-1 and delay the development of diabetic nephropathy.",
        "keywords": [
            "Diabetes mellitus",
            "Cilostazol",
            "experimental",
            "Cell adhesion molecules",
            "Diabetic nephropathies"
        ],
        "authors": [
            {
                "name": "LI Mei",
                "org": "Centeral Laboratory,Shandong Provincial Hospital,Jinan ,Shandong,China;Institute of Pharmacology,School of Medicine,Shandong University,Jinan ,Shandong,China"
            },
            {
                "name": "GAO Ling",
                "org": "Centeral Laboratory,Shandong Provincial Hospital,Jinan ,Shandong,China"
            },
            {
                "name": "HU Jian-ting",
                "org": "Centeral Laboratory,Shandong Provincial Hospital,Jinan ,Shandong,China;Institute of Pharmacology,School of Medicine,Shandong University,Jinan ,Shandong,China"
            },
            {
                "name": "BIAN Li-xiang",
                "org": "Department of Endocrinology,Shandong Provincial Hospital,Jinan ,Shandong,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Centeral Laboratory,Shandong Provincial Hospital,Jinan ,Shandong,China"
            },
            {
                "name": "CUI Bin",
                "org": "Centeral Laboratory,Shandong Provincial Hospital,Jinan ,Shandong,China"
            },
            {
                "name": "ZHAO Jia-jun",
                "org": "Department of Endocrinology,Shandong Provincial Hospital,Jinan ,Shandong,China"
            },
            {
                "name": "ZHANG Xiu-mei",
                "org": "Institute of Pharmacology,School of Medicine,Shandong University,Jinan ,Shandong,China"
            }
        ],
        "venue": "Journal of Shandong University(Health Sciences)",
        "year": 2006
    },
    "rn51bx0i": {
        "id": "rn51bx0i",
        "title": "The effects of anticardiolipin antibody(ACA) positive blood sera from patients with recurrent spontaneous abortion on the development of trophoblast",
        "abstract": "Objective To evaluate the adverse effects of anticardiolipin antibody (ACA) positive blood sera from patients suffering from recurrent spontaneous abortion on the development of trophoblast and determine the role of aspirin in regulating these functions. Methods Gight patients with recurrent pregnancy loss whose anticardiolipin antibody was positive and 8 healthy women with history of term delivery were selected. BeWo cells were cultured in sera from patients and helathy women with and without aspirin.Viability was assessed by using MTT reduction test,M30 expression was assessed by flow cytofluorometry and secretion of β-HCG promoted by forskolin was assessed by ELISA.Results The value of 490nmmOD and β-HCG contentration in the study group decreased significantly compared with the control group (0.02061±0.0191 vs 0.2414±0.0320)and [(19.4488±1.8132)U/L vs (22.9900±2.2568(U/L](P<0.05),while the M30 expression increased significantly[(4.7868±0.5170)% vs (0.7900±0.1786)%](P<0.05).Afcer adding aspirin,the value of 490 nmOD in the control group was 0.2411±0.0329,β-HCG concentration was (23.2288±2.0581)U/L,and M30 expression was (0.6325±0.1701)%,P>0.05,compared to before adding,while in the study group,they were 0.2369±0.0311,(21.5675±1.3338)U/L and (2.7037±0.8920)%,respectively,P<0.05,compared to before adding.Conclusion Besides thrombosis, ACA have direct effects on trophoblast biology .Aspirin can reverse these effects to some degree,providing an additional mechanism to explain the clinical benefits on recurrent pregnancy loss.",
        "keywords": [
            "aspirin",
            "anticardiolipin antibodies",
            "BeWo cell",
            "recurrent spontaneous abortion"
        ],
        "authors": [
            {
                "name": "YU Xiao-yan",
                "org": ".Shandong Provincial Hospital,Shandong University,Jinan ,China"
            },
            {
                "name": "WANG Xie-tong",
                "org": ".Shandong Provincial Hospital,Shandong University,Jinan ,China"
            },
            {
                "name": "LIU Zong-hua",
                "org": ".Shandong Provincial Hospital,Shandong University,Jinan ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": ".Shandong Provincial Hospital,Shandong University,Jinan ,China"
            }
        ],
        "venue": "Chinese Journal of Practical Gynecology and Obstetrics",
        "year": 2008
    },
    "wi8h3Rfi": {
        "id": "wi8h3Rfi",
        "title": "Construction of recombinant plasmid vector pIRES-CD and its expression in ACC-2 cells]",
        "abstract": "To clone CD gene, construct its eukaryotic expression vector pIRES-CD and obtain positive ACC-2 cells expressing E.coli CD gene stably.PCR amplification was performed using primers based on E.coli CD gene sequence from Genebank, E.coli genomic DNA as template. PCR product was inserted into pMD18-T. After sequence confirmation, the gene was subcloned to pIRES to construct recombinant eukaryotic expression vector pIRES-CD. Then the combinant plasmid was conducted into ACC-2 cell by electroporation. ACC-2 cells stably expressing CD was obtained by 10-day positive selection with 400 mug/mL G418. Total RNA was extracted and the expression of the CD gene in transfected ACC-2 cells was identified by RT-PCR.PCR yielded a fragment of 1280bp and CD was verified by sequence analysis. A fragment of 6.1kb and inserted fragment of 1280bp were obtained by cutting positive recombinant plasmid of pIRES-CD with XbaI and NotI. RT-PCR analysis demonstrated that CD gene could be effectively expressed in ACC-2 cells.The CD gene is successfully amplified and the eukaryotic expression plasmid containing E.coli CD is successfully constructed.The positive ACC-2 cell clones expressing CD gene stably are obtained, which provide a basis for further study of adenoid cystic carcinoma gene therapy with CD/5-FC suicide gene system. Supported by Natural Science Foundation of Shandong Province(Grant No.Z2003C03).",
        "keywords": [
            "cytosine deaminase",
            "suicide gene",
            "endonuclease",
            "adenoid cystic carcinoma",
            "internal ribosome entry site"
        ],
        "authors": [
            {
                "name": "Sheng-Yun Huang",
                "org": "1.Department of Oral and Maxillofacial Surgery,"
            },
            {
                "name": "Dong-Sheng Zhang",
                "org": "1.Department of Oral and Maxillofacial Surgery,"
            },
            {
                "name": "Shi-Zhou Zhang",
                "org": "1.Department of Oral and Maxillofacial Surgery,"
            },
            {
                "name": "Gui-Jun Liu",
                "org": "1.Department of Oral and Maxillofacial Surgery,"
            },
            {
                "name": "Wen-Li Mu",
                "org": "2.Medical Research Center,Shandong Provincial Hospital,Shandong University.Jinan ,Shandong Province,China"
            },
            {
                "name": "Jie Zhang",
                "org": "2.Medical Research Center,Shandong Provincial Hospital,Shandong University.Jinan ,Shandong Province,China"
            }
        ],
        "venue": "Shanghai kou qiang yi xue = Shanghai journal of stomatology",
        "year": 2008
    },
    "C3kqDiao": {
        "id": "C3kqDiao",
        "title": "Construction of recombinant plasmid TK and its expression in ACC -2 cells",
        "abstract": "Objective:To clone TK gene,construct its eukaryotic expression vector pIRES-TK and obtain positive ACC-2 cells expressing TK gene stably.Method:PCR amplification was performed using primers based on TK gene se-quence from Genebank,pLNSX-TK DNA as template.PCR product was inserted into pMD18-T.After the sequencing was confirmed,the gene was subcloned to pIRES to construct recombinant eukaryotic expression vector pIRES-TK.Then the combinant plasmid was conducted into ACC-2 cell by electroporation.ACC-2 cells stably expressing TK was obtained by positive select with G418.Total RNA was extracted and the expression of the TK gene in transfected ACC-2 cells was i-dentified by RT-PCR.Result:PCR yielded a fragment of 1128 bp and TK was verified by sequence analysis.A fragment of 2692 bb and inserted fragment of 1128 bp were got by cutting positive recombinant plasmid of pIRES-TK with XhoI and MulI.RT-PCR analysis demonstrated that TK gene could be effectively expressed in ACC-2 cells.Conclusion:The TK gene was successfully amplified and the eukaryotic expression plasmid containing TK was successfully constructed.The positive ACC-2 cell clones expressing TK gene stably were obtained,which has laid a solid ground for further study of adenoid cystic carcinoma gene therapy with TK/GCV suicide gene system.",
        "keywords": [
            "adenoid cystic carcinoma",
            "transfection",
            "suicide gene",
            "endonuclease",
            "thymidine kinase"
        ],
        "authors": [
            {
                "name": "HUANG Sheng-yun",
                "org": ".Department of Oral and Maxillofacial Surgery,Shandong Provincial Hospital,Shandong University.Jinan ,China"
            },
            {
                "name": "ZHANG Dong-sheng",
                "org": ".Department of Oral and Maxillofacial Surgery,Shandong Provincial Hospital,Shandong University.Jinan ,China"
            },
            {
                "name": "LIU Gui-jun",
                "org": ".Department of Oral and Maxillofacial Surgery,Shandong Provincial Hospital,Shandong University.Jinan ,China"
            },
            {
                "name": "MU Wen-li",
                "org": ".Department of Oral and Maxillofacial Surgery,Shandong Provincial Hospital,Shandong University.Jinan ,China"
            },
            {
                "name": "ZHANG Shi-zhou",
                "org": ".Department of Oral and Maxillofacial Surgery,Shandong Provincial Hospital,Shandong University.Jinan ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": ".Department of Oral and Maxillofacial Surgery,Shandong Provincial Hospital,Shandong University.Jinan ,China"
            }
        ],
        "venue": "Journal of Clinical Stomatology",
        "year": 2008
    },
    "25AiV4W4": {
        "id": "25AiV4W4",
        "title": "Effect of the CD4~+ T lymphocyte in the development of viral myocarditis in mice",
        "abstract": "Objective To investigate the effect of the CD4+ T lymphocyte in the development of experimental coxsackievirus B3(CVB3) myocarditis in mice.Methods A total of 70 BALB/c mice used in the experiments,were randomly divided into the control group and the CVB3 infection group.The mice in the CVB3 infection group were intraperitoneally inoculated with 0.15 ml TCID50 109/ml CVB3 and the mice in the control group with 0.15 ml eagle reagent.The mice were sacrificed on 7,10,14,21 and 28 days post-inoculation and then the hearts were aseptically removed.Pathological changes in the myocardium were observed by light microscopy and the expression of the CD4+ T lymphocyte in the myocardium was determined by immunohistochemistry.Results The CD4+ T lymphocyte was found in the myocardium in the CVB3 infection group.There was a significantly positive correlation between the expression of the CD4+ T lymphocyte and changes of myocardial histopathological scores(r=0.98,P<0.01).The expression of the CD4+ T lymphocyte reached a peak during 10 to 14 days(P<0.01).Conclusion The CD4+ T lymphocyte leads to myocardial damage while cleaning the virus in experimental CVB3 myocarditis.",
        "keywords": [
            "Viral diseases",
            "CD4+ T lymphocyte",
            "Myocarditis",
            "Mice"
        ],
        "authors": [
            {
                "name": "LIU Zhen-hu",
                "org": "Department of Pediatrics,Provincial Hosiptal Affiliated to Shandong University,Jinan ,China"
            },
            {
                "name": "HAN Bo",
                "org": "Department of Pediatrics,Provincial Hosiptal Affiliated to Shandong University,Jinan ,China"
            },
            {
                "name": "GUO Chun-yan",
                "org": "Department of Pediatrics,Provincial Hosiptal Affiliated to Shandong University,Jinan ,China"
            },
            {
                "name": "CHANG Hong",
                "org": "Department of Pediatrics,Provincial Hosiptal Affiliated to Shandong University,Jinan ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Pediatrics,Provincial Hosiptal Affiliated to Shandong University,Jinan ,China"
            },
            {
                "name": "HAN Xiu-zhen",
                "org": "Department of Pediatrics,Provincial Hosiptal Affiliated to Shandong University,Jinan ,China"
            }
        ],
        "venue": "Journal of Shandong University(Health Sciences)",
        "year": 2008
    },
    "ZgVCi13c": {
        "id": "ZgVCi13c",
        "title": "Effected of radioactive ray on the expression of NF-κB p65 in human oral squamous cell carcinoma",
        "abstract": "Objective:To investigate the effected of radioactive ray on the expression of NF-κB p65 in human oral squamous cell carcinoma. Method:To adopt the squamous cell carcinoma of tongue Tca8113 cell,the experiment was divided into six groups,0、2、4、6、8 and 10 Gy group. To use immunocyteochemistry to detect the NF-κB p65 protein after irradiation in various times(1、3、6、10、24、48 h) .To apply the Leica Qwin Plus image analytical system to analyzed the gray scale. Result:To compare the brtween various dose group and 0 Gy group,the P <0.05,the difference was statistical significance. The difference of average gray scale between 3h group and other different time group was significance(P <0.05) . Conclusion:Radioactive ray can activitate the NF-κB p65 of oral squmaous cell carcinoma cell.NF-κB p65 maybe an important activity in the tumor radiotherapy.",
        "keywords": [
            "p65",
            "radioactive ray",
            "oral squamous cell"
        ],
        "authors": [
            {
                "name": "MA Li",
                "org": ". 1.Department of Oral ang Maxillafacial Surgery,Shandong Provincial Hospital,Shandong University.Shandong Jinan ,China"
            },
            {
                "name": "ZHANG Dong-sheng",
                "org": ". 1.Department of Oral ang Maxillafacial Surgery,Shandong Provincial Hospital,Shandong University.Shandong Jinan ,China"
            },
            {
                "name": "HAN Jun-qing",
                "org": "Cancer Center of Shandong Provincial Hospital,Shandong University.Shandong Jinan ,China"
            },
            {
                "name": "ZHANG Shi-zhou",
                "org": ". 1.Department of Oral ang Maxillafacial Surgery,Shandong Provincial Hospital,Shandong University.Shandong Jinan ,China"
            },
            {
                "name": "LIU Gui-jun",
                "org": ". 1.Department of Oral ang Maxillafacial Surgery,Shandong Provincial Hospital,Shandong University.Shandong Jinan ,China"
            },
            {
                "name": "MU Wen-li",
                "org": "Medical Research Center of Shandong Provincial Hospital,Shandong University.Shandong Jinan ,China."
            },
            {
                "name": "ZHANG Jie",
                "org": "Medical Research Center of Shandong Provincial Hospital,Shandong University.Shandong Jinan ,China."
            }
        ],
        "venue": "Journal of Clinical Stomatology",
        "year": 2009
    },
    "JX1Z8r4H": {
        "id": "JX1Z8r4H",
        "title": "Construction of eukaryotic expression vectors of human HMGB1 and its expression in monocytes",
        "abstract": "Objective To construct the eukaryotic expression vectors of human HMGB1 gene and investigate its immunomodulatory effect.Methods The HMGB1 gene fragment was isolated from cloning vector pMD-HMGB1 with digestion of Sal I and EcoR I and agarose gel separation,and inserted into the same sites of eukaryotic expression vector pCITE-EGFP.The recombinant plasmid was screened by colony PCR and restriction enzyme digestion.The human monocyte cell line U937 was transfected with recombinant expression plasmid and screened by gradient G4l8.Expression of HMGB1 was determined under an inverted fluorescence microscope and Western blotting.Results Colony PCR and the restriction endonuclease digestion showed that the HMGB1 gene was correctly inserted into the eukaryotic expression vector and the recombinant plasmid pCITE-EGFP-HMGB1 was obtained.With an increase of G418 concentration in the culture medium,the U937 cells stably expressing human HMGB1 were established.The quantity of HMGB1 in the transfected cells was increased.Conclusion The eukaryotic vector of pCITE-EGFP-HMGB1 was successfully constructed and a human monocyte cell line stably expressing HMGB1 was obtained,which established a solid foundation for further study on the effects and mechanisms of HMGB1on mononuclear-macrophages.",
        "keywords": [
            "eukaryotic cells",
            "high mobility group proteins",
            "monocytes",
            "recombinant dna",
            "polymerase chain reaction",
            "cell lines",
            "genes",
            "gene expression"
        ],
        "authors": [
            {
                "name": "XU Jie",
                "org": "Institute of Basic Medicine,Shandong Academy of Medical Sciences,Jinan ,China"
            },
            {
                "name": "CUI Bin",
                "org": "Medical Research Center,Provincial Hospital Affiliated to Shandong University,Jinan ,China"
            },
            {
                "name": "JIAO Yu-lian",
                "org": "Medical Research Center,Provincial Hospital Affiliated to Shandong University,Jinan ,China"
            },
            {
                "name": "YOU Li",
                "org": "Medical Research Center,Provincial Hospital Affiliated to Shandong University,Jinan ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Medical Research Center,Provincial Hospital Affiliated to Shandong University,Jinan ,China"
            },
            {
                "name": "LIU Xiao-wen",
                "org": "Medical Research Center,Provincial Hospital Affiliated to Shandong University,Jinan ,China"
            },
            {
                "name": "QU Yun-yun",
                "org": "Medical Research Center,Provincial Hospital Affiliated to Shandong University,Jinan ,China"
            },
            {
                "name": "ZHU Min",
                "org": "Medical Research Center,Provincial Hospital Affiliated to Shandong University,Jinan ,China"
            },
            {
                "name": "SUN Xin-ping",
                "org": "Medical Research Center,Provincial Hospital Affiliated to Shandong University,Jinan ,China"
            },
            {
                "name": "ZHAO Yue-ran",
                "org": "Institute of Basic Medicine,Shandong Academy of Medical Sciences,Jinan ,China;Medical Research Center,Provincial Hospital Affiliated to Shandong University,Jinan ,China"
            }
        ],
        "venue": "Journal of Shandong University(Health Sciences)",
        "year": 2009
    },
    "Eoh2PbVg": {
        "id": "Eoh2PbVg",
        "title": "Influence of Carvedilol on Apoptosis and Expression of Bcl-2/Bax Protein of Cultured Cardiomyocytes Infected by Coxsackievirus B3",
        "abstract": "Objective To investigate the effects of carvedilol on apoptosis and expression of Bcl-2/Bax protein of cultured cardiomyocytes infected by coxsackievirus B3(CVB3).Methods Cardiomyocytes derived from neonatal Wistar rats were purified by differential adhesion method.There were 4 groups:CVB3 group,carvedilol group,metoprolol group and normal control group.The cardiomyocytes of the first 3 groups were infected by CVB3 and then added by serum-free dulbecco's modified eagle medium(DMEM),carvedilol media,metoprolol media,respectively.The cardiomyocytes in normal control group were added by serum-free DMEM.The histopathologic changes and rhythmical beat of cardiomyocytes were observed by inverted phase contrast after 72 h.Superoxide dismutase(SOD)activity and malondialdehyde(MDA)content in the culture media were measured by xanthine oxidase method and thiobarbituric acid method,respectively.Flow cytometry was used to detect cardiomyocytes apoptosis.The expression of Bcl-2 and Bax protein in cardiomyocytes were determined by immunocytochemistry.Results 1.Compared with CVB3 group,the beating rate of cardiomyocytes and SOD activity in culture media were significantly increased(Pa<0.05),MDA content in culture media and cardiomyocytes apoptosis were significantly decreased in carvedilol group(Pa<0.05).There was no significant difference in the beating rate,cardiomyocytes apoptosis,SOD activity,and MDA content between the metoprolol group and CVB3 group(Pa>0.05).2.The expression of Bcl-2 protein of cardiomyocyte in carvedilol group was stronger than that of CVB3 group and metoprolol group,while the expression of Bax protein of cardiomyocyte was significantly decreased.Conclusions Carvedilol is effective in inhibiting apoptosis of CVB3-infected cultured cardiomyocytes,which may be due to its antioxidation capacity,upregulation of Bcl-2 and downregulation of Bax of cardiomyocytes.",
        "keywords": [
            "Bax",
            "apoptosis",
            "cardiomyocyte",
            "Bcl-2",
            "carvedilol",
            "coxsackievirus B3"
        ],
        "authors": [
            {
                "name": "XI Jun-fang",
                "org": "Department of Pediatric Cardiology,Provincial Hospital Affiliated to Shandong University,Jinan ,Shandong Province,China"
            },
            {
                "name": "HAN Bo",
                "org": "Department of Pediatric Cardiology,Provincial Hospital Affiliated to Shandong University,Jinan ,Shandong Province,China"
            },
            {
                "name": "CHEN Yong-fen",
                "org": "Department of Pediatric Cardiology,Provincial Hospital Affiliated to Shandong University,Jinan ,Shandong Province,China"
            },
            {
                "name": "GAO Ling",
                "org": "Central of Laboratory,Provincial Hospital Affiliated to Shandong University,Jinan ,Shandong Province,China"
            },
            {
                "name": "MA Chun-yan",
                "org": "Central of Laboratory,Provincial Hospital Affiliated to Shandong University,Jinan ,Shandong Province,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Central of Laboratory,Provincial Hospital Affiliated to Shandong University,Jinan ,Shandong Province,China"
            },
            {
                "name": "LU Kang",
                "org": "Department of Pediatric Cardiology,Provincial Hospital Affiliated to Shandong University,Jinan ,Shandong Province,China"
            },
            {
                "name": "SUN Shi-jing",
                "org": "Department of Pediatric Cardiology,Provincial Hospital Affiliated to Shandong University,Jinan ,Shandong Province,China"
            }
        ],
        "venue": "Journal of Applied Clinical Pediatrics",
        "year": 2010
    },
    "0RZSKJtE": {
        "id": "0RZSKJtE",
        "title": "Therapeutic Role of CD_(40) Immunoglobulin Chimera Protein by Blocking T Cell Costimulatory Signals in Mice with Viral Myocarditis",
        "abstract": "Objective To investigate the effect of CD40immunoglobulin(CD40Ig) chimera protein on the mortality,viral replication and pathologic changes of myocardium in mice with viral myocarditis(VMC) induced by coxsackievirus B3(CVB3).Methods One hundred and six healthy male BALB/c mice,4 to 6 weeks old,with weight of 12 to 16 g,were divided into CD40Ig group(n=16),CVB3 group(n=40),IgG group(n=40) and normal control group(n=10),randomly.Each mouse in CD40Ig group,CVB3 group and IgG group was inoculated intraperitoneally with 0.15 mL CVB3 of 10-3·L-1 50% tissue culture interactive dose(TCID50) and each mouse in normal control group with 0.15 mL Eagle reagent.Each mouse in CD40Ig group and IgG group was inoculated with CD40Ig(0.1 mg·kg-1) and IgG(0.1 mg·kg-1) 6 hours and 72 hours post inoculation,respectively.The surplus mice in each group were sacrificed on day 7 post inoculation.The histopathologic changes were observed by light microscope and the myocardial histopathology scores were calculated.Real-time quantitative-polyme-rase chain reaction(RQ-PCR) was used to detect the expression of CVB3 mRNA of myocardium.The expression of CD40 protein in myocardium was determined by immunohistochemistry.Results The mice mortality(80% vs 50%,P<0.05),myocardial histopathology score [(8.88±2.95) score vs(3.42±1.21) score,P<0.05] and myocardial CVB3 mRNA(3.48±2.89 vs 0.91±0.75 P<0.05) in CD40Ig group were lower than those in CVB3 group.CD40 expressions were observed in both myocardium of CVB3 group and CD40Ig group.There was strong expression of CD40 on the membrane of infiltrating cells,and on the membrane and cytoplasm of cardiac myocytes in the inflammatory areas of myocardium.Conclusions It is suggested that CD40Ig can relieve myocardial inflammation,decrease myocardial virus replication and mice mortality in CVB3-induced viral myocarditis.CD40Ig might reduce myocardial injury by blocking the interaction of CD40 with CD40L and inhibiting T lymphocyte activation.",
        "keywords": [
            "CD40 immunoglobulin chimera protein",
            "mouse",
            "viral myocarditis"
        ],
        "authors": [
            {
                "name": "LU Kang",
                "org": "Department of Pediatric Cardiology,Provincial Hospital Affiliated to Shandong University,Jinan ,Shandong Province,China"
            },
            {
                "name": "HAN Bo",
                "org": "Department of Pediatric Cardiology,Provincial Hospital Affiliated to Shandong University,Jinan ,Shandong Province,China"
            },
            {
                "name": "ZHANG Yi",
                "org": "Department of Pediatric Cardiology,Provincial Hospital Affiliated to Shandong University,Jinan ,Shandong Province,China"
            },
            {
                "name": "ZHAO Li-jian",
                "org": "Department of Pediatric Cardiology,Provincial Hospital Affiliated to Shandong University,Jinan ,Shandong Province,China"
            },
            {
                "name": "XI Jun-fang",
                "org": "Department of Pediatric Cardiology,Provincial Hospital Affiliated to Shandong University,Jinan ,Shandong Province,China"
            },
            {
                "name": "ZHANG Jian-jun",
                "org": "Department of Pediatric Cardiology,Provincial Hospital Affiliated to Shandong University,Jinan ,Shandong Province,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Central Laboratory,Provincial Hospital Affiliated to Shandong University,Jinan ,Shandong Province,China"
            }
        ],
        "venue": "Journal of Applied Clinical Pediatrics",
        "year": 2010
    },
    "uzHcUtlZ": {
        "id": "uzHcUtlZ",
        "title": "Construction of recombinant prokaryotic expression plasmid of human high mobility group box1 and its expression and purification",
        "abstract": "Objective To construct the prokaryotic expression plasmid of human high mobility group box1 (hHMGB1) gene,and to express and purify the His-tagged hHMGB1 fusion protein. Methods According to the sequence reported in GenBank,we optimized codons by OptimumGeneTM and synthesized the human HMGB1 gene. To construct prokaryotic expression plasmid pQE-T7-2 /HMGB1,the DNA fragment obtained from PCR was digested with NdeⅠ and Xho Ⅰ,and then inserted into pQE-T7-2 that was cut with the same enzymes. The recombinants were screened by colony PCR,restriction mapping and sequencing. The recombinant E. coli BL21 (DE3) was induced for expression with isopropyl-beta-D-thiogalactopyranoside (IPTG),and the recombinant protein was identified by SDS-PAGE and Western blotting. The recombinant human HMGB1 was further purified by Ni-NTA Agarose. Results The prokaryotic expression plasmid pQE-T7-2 /HMGB1 was successfully constructed. The expressed recombinant protein accounted for about 20% of the total bacterial proteins. The recombinant protein could specifically react with anti-HMGB1 antibody and anti-His antibody. The purity of recombinant human HMGB1 separated with affinity chromatography was more than 90% . Conclusion The recombinant prokaryotic expression vector of human HMGB1 which was successfully constructed may lay the foundation for the further study of the function of human HMGB1.",
        "keywords": [
            "Escherichia coli",
            "High mobility group proteins",
            "Purification",
            "Prokaryotic cells"
        ],
        "authors": [
            {
                "name": "CUI Bin",
                "org": " Institute of Basic Medicine,Shandong Academy of Medical Sciences,Jinan ,China; Central Laboratory,Provincial Hospital Affiliated to Shandong University,Jinan ,China"
            },
            {
                "name": "WANG Lai-cheng",
                "org": " Central Laboratory,Provincial Hospital Affiliated to Shandong University,Jinan ,China"
            },
            {
                "name": "ZHU Min",
                "org": " Central Laboratory,Provincial Hospital Affiliated to Shandong University,Jinan ,China"
            },
            {
                "name": "JIAO Yu-lian",
                "org": " Central Laboratory,Provincial Hospital Affiliated to Shandong University,Jinan ,China"
            },
            {
                "name": "XIN Wei",
                "org": " Central Laboratory,Provincial Hospital Affiliated to Shandong University,Jinan ,China"
            },
            {
                "name": "MA Chun-yan",
                "org": " Central Laboratory,Provincial Hospital Affiliated to Shandong University,Jinan ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": " Central Laboratory,Provincial Hospital Affiliated to Shandong University,Jinan ,China"
            },
            {
                "name": "ZHAO Yue-ran",
                "org": " Central Laboratory,Provincial Hospital Affiliated to Shandong University,Jinan ,China"
            }
        ],
        "venue": "Journal of Shandong University(Health Science)",
        "year": 2010
    },
    "TuttYnRq": {
        "id": "TuttYnRq",
        "title": "Effects of low molecular weight heparin on the rat model of alcoholic liver disease",
        "abstract": "Objective To study the effect of low molecular weight heparin on alcohol-fed rats. Methods The rat model of alcoholic liver disease was established by alcohol lavage,and then treated with low molecular weight heparin(100 IU/kg).After 4 weeks,blood and liver tissue samples were collected.The effect of low molecular weight heparin on alcoholic liver disease rats was observed by pathology,ultrastructures and molecular immunology.Results Compared with the model group,the low molecular weight heparin therapy group significantly improved the levels of aspartate aminotransferase,total cholesterol and low density lipoprotein(P<0.01),while it lowered the serum leptin level(P<0.05).Under observation by optical and electronic microscopes,degrees of liver steatosis,inflammation reaction and fibrosis were significantly reduced(P<0.01).Conclusion Low molecular weight heparin has a therapeutic effect on alcohol-induced liver disease rats by improving fat metabolism and reducing serum leptin.",
        "keywords": [
            "Leptin",
            "low-molecular-weight",
            "Liver disease",
            "alcoholic",
            "Heparin"
        ],
        "authors": [
            {
                "name": "YAN Chun-ying",
                "org": "Department of Liver Diseases"
            },
            {
                "name": "SHI Jun",
                "org": "Department of Liver Diseases"
            },
            {
                "name": "HAO Jing-hua",
                "org": "Department of Liver Diseases"
            },
            {
                "name": "ZHANG Jie",
                "org": "Central Laboratory,Provincial Hospital Affiliated to Shandong University,Jinan ,China"
            },
            {
                "name": "SUN Lin-lin",
                "org": "Department of Liver Diseases"
            },
            {
                "name": "REN Wan-hua",
                "org": "Department of Liver Diseases"
            }
        ],
        "venue": "Journal of Shandong University(Health Sciences)",
        "year": 2011
    },
    "GRdcu70Z": {
        "id": "GRdcu70Z",
        "title": "Relationship between P65 and radiotherapy-induced oral squamous cell carcinoma cell line apoptosis]",
        "abstract": "To investigate the effects of different X-ray doses on the expression of nuclear factor-kappaB (NF-kappaB) P65 in human oral squamous cell carcinoma cell (OSCC) line and the relationship between NF-kappaB P65 and radiation-induced OSCC cell line apoptosis.The squamous cell carcinoma of Tca8113 cell was cultivated in the 37 degrees C, 5% CO2 incubator after recovery. The experiment samples were divided into six groups (control group, 2, 4, 6, 8, 10 Gy). After growing to logarithm period, Tca8113 cells were irradiated using above-mentioned X-ray doses. The immunocyteochemistry and Western blot were used to detect the expression of NF-kappaB P65 after irradiation in various times (1, 3, 6, 10, 24, 48 h). The apoptosis rates under different radiotherapy dose were detected by flow cytometer and TDT-mediated dUTP-biotin nick end labeling (TUNEL).Compared with the control group, cytoplasm expression of P65 under different X-ray doses had statistically significant differences (P < 0.05). While the cytoplasm P65 protein expression at different time were compared each other, the 3 h group demonstrated significant difference (P < 0.05). Apoptosis rates in various groups, compared with control group, had statistically significant differences (P < 0.05). While the groups at different time points were compared each other, the apoptosis rates of 3 h group had significant differences (P < 0.05).X-ray can activate the NF-kappaB P65 in oral squmaous cell carcinoma cell lines. The correlation between expressional quantity of P65 and radiotherapy induced apoptosis of oral squamous cell carcinoma cell lines possesses positive correlation. The activated and intranuclear P65 may have radiotherapy resistant effect.",
        "keywords": [
            "cell apoptosis",
            "p65",
            "oral squamous cell carcinoma"
        ],
        "authors": [
            {
                "name": "Li Ma",
                "org": " Dept.of Oral and Maxillofacial Surgery,Provincial Hospital Affiliated to Shandong University,Jinan ,China"
            },
            {
                "name": "Dong-Sheng Zhang",
                "org": " Dept.of Oral and Maxillofacial Surgery,Provincial Hospital Affiliated to Shandong University,Jinan ,China"
            },
            {
                "name": "Jun-Lou Wu",
                "org": " Dept.of Oral and Maxillofacial Surgery,Provincial Hospital Affiliated to Shandong University,Jinan ,China"
            },
            {
                "name": "Jun-Qing Han",
                "org": "Cancer Center,Provincial Hospital Affiliated to Shandong University,Jinan ,China"
            },
            {
                "name": "Shi-Zhou Zhang",
                "org": " Dept.of Oral and Maxillofacial Surgery,Provincial Hospital Affiliated to Shandong University,Jinan ,China"
            },
            {
                "name": "Gui-Jun Liu",
                "org": " Dept.of Oral and Maxillofacial Surgery,Provincial Hospital Affiliated to Shandong University,Jinan ,China"
            },
            {
                "name": "Wen-Li Mu",
                "org": "Medical Research Center,Provincial Hospital Affiliated to Shandong University,Jinan ,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Medical Research Center,Provincial Hospital Affiliated to Shandong University,Jinan ,China"
            }
        ],
        "venue": "Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology",
        "year": 2011
    },
    "7DhSEFCu": {
        "id": "7DhSEFCu",
        "title": "Effect of aldose reductase inhibitor on rat kidney aldose reductase gene expression",
        "abstract": "Objective: To investigate the effect of an aldose reductase inhibitor (ARI)-epalrestat on AR mRNA level of rat kidney and renal function. Methods: To establish the diabetic nephropathy animal model by an injection of streptozotocin following unilateral kidney ligation. There are four groups including control group, model group, low dose group and high dose group. Low dose group and high dose group was given aldose reductase inhibitor epalrestat 50 mg/kg and 100 mg/kg respectively by intragastric administration, which last for 4 weeks. The level of AR mRNA of rat kidney was analyzed by quantitatively RT-PCR method and evaluate the effect of epalrestat on AR mRNA level between groups.Results: The level of renal function is significantly different between diabetic nephropathy groups and normal controls, but there is no significant difference between the groups given epalrestat and groups without epalrestat. AR mRNA level in rat kidney of diabetic nephropathy is significantly higher than that in rat kidney of normal controls. After given epalrestat 4 weeks, the level of AR mRNA decrease, but there is no significant difference between low dose groups and high dose groups. Conclusion: Rats with diabetic nephropathy have a significantly higher expression of AR mRNA in kidney than normal controls. Epalrestat have no effect on renal function of rats with diabetic nephropathy, but AR mRNA level decrease after given epalrestat for 4 weeks. Rats rendered diabetic by an injection of streptozocin, following half kidney ligation, are an excellent model of diabetic nephropathy.",
        "keywords": [
            "Gene expression",
            "Aldose reductase inhibitor",
            "Aldose Reductase",
            "Diabetic nephropathy"
        ],
        "authors": [
            {
                "name": "YU De-min",
                "org": "Metabolic Diseases Hospital of Tianjin Medical University, Tianjin ,China"
            },
            {
                "name": "LIU De-min",
                "org": "Metabolic Diseases Hospital of Tianjin Medical University, Tianjin ,China"
            },
            {
                "name": "LIU Xiao-hui",
                "org": "Metabolic Diseases Hospital of Tianjin Medical University, Tianjin ,China"
            },
            {
                "name": "SUN Ying",
                "org": "Metabolic Diseases Hospital of Tianjin Medical University, Tianjin ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Metabolic Diseases Hospital of Tianjin Medical University, Tianjin ,China"
            }
        ],
        "venue": "Journal of Tianjin Medical University",
        "year": 2005
    },
    "fU3dBSYS": {
        "id": "fU3dBSYS",
        "title": "Correlation between polymorphism of SUR1 gene and type 2 diabetes",
        "abstract": "Objective: To study the relationship between polymorphism and human sulfonylurea receptor1 (SUR1) gene in type 2 diabetes mellitus(T2DM). Methods: 136 normal subjects and 173 patients with T2DM in Tianjin were included. Genomic DNA was extracted from white cells of peripheral blood. The aim fragment containing polymorphism site was amplified by PCR and then was digested by restrictive enzymes(PCR-RFLP).The mutations were sequenced to verify the consistency. Results: The mutation frequency in intron 24 in normal subjects was significantly higher than that in patients with T2DM(P<0.05). Conclusion: SUR1 gene is possibly a susceptible gene for T2DM in Tianjin.",
        "keywords": [
            "Polymorphism",
            "T2DM",
            "SUR1",
            "Restriction fragment length"
        ],
        "authors": [
            {
                "name": "SUN Ying",
                "org": "The Metabolic Hospital of Tianjin Medical University,Tianjin ,China"
            },
            {
                "name": "LIU De-min",
                "org": "The Metabolic Hospital of Tianjin Medical University,Tianjin ,China"
            },
            {
                "name": "JIN Li-zhong",
                "org": "The Metabolic Hospital of Tianjin Medical University,Tianjin ,China"
            },
            {
                "name": "FANG Xian-feng",
                "org": "The Metabolic Hospital of Tianjin Medical University,Tianjin ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "The Metabolic Hospital of Tianjin Medical University,Tianjin ,China"
            }
        ],
        "venue": "Journal of Tianjin Medical University",
        "year": 2005
    },
    "AFGUOuKG": {
        "id": "AFGUOuKG",
        "title": "Study on the Clone of Human Adiponectin Gene and Its Expression in Escherichia Coli",
        "abstract": "Objective: To clone human adiponectin gene and identify its expression in E.coli. Methods: Total RNA was extracted from human subcutaneous adipose tissue and a full length cDNA was obtained by RT-PCR. The product was ligated to pMD-18T vector, and was sequenced and constructed to the expression vector in pET-DEST 42, and the expression was induced by IPTG in E.coli. Results: A high level expression was obtained by 0.4mmol/L IPTG inducement in recombined adiponectin E.coli. Conclusion: Human adiponectin gene in E.coli is successfully cloned and expressed.",
        "keywords": [
            "intercellular signaling peptides and proteins cloning",
            "molecular gene expression escherichia coli"
        ],
        "authors": [
            {
                "name": "LIU Demin",
                "org": "Tianjin Medical University Metabolic Hospital, Tianjin , China"
            },
            {
                "name": "YANG Lili",
                "org": "Tianjin Medical University Metabolic Hospital, Tianjin , China"
            },
            {
                "name": "SUN Ying",
                "org": "Tianjin Medical University Metabolic Hospital, Tianjin , China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Tianjin Medical University Metabolic Hospital, Tianjin , China"
            }
        ],
        "venue": "Tianjin Medical Journal",
        "year": 2006
    },
    "03T4wqbu": {
        "id": "03T4wqbu",
        "title": "The effect of LiCl on the expression of rat hepatocype glucose-6-phosphatase",
        "abstract": "Objective:To study the effect of LiCl on the expression of rat hepatocype glucose-6-phosphatase.Methods:The primary hepatocyte was cultured in different concentrations of glucose and LiCl.Total RNA was extracted after 4 hours incubated with glucose or LiCl.The mRNA of glucose-6-phosphatase catalytic(G6PC)gene and the putative glucose-6-phosphate translocase(G6PT)gene were measured by semiquantitative RT-PCR.Results:The rat hepatocyte cultured with the medium containing LiCl-the inhibitor of GSK and Glu(25mM)for 4 hours,both the mRNA level of P36 and P46 decreased significantly(P<0.05).Conclusion:The inhibitor of glycogen synthase kinase LiCl can both decrease the mRNA level of P36 and P46.The hyperglycemia of diabetes can be amelioratea by intervening the experssion of glucose-6-phosphatase.",
        "keywords": [
            "Gene expression",
            "Hepatocyte cell culture",
            "Glucose-6-phosphatase",
            "LiCl",
            "Diabetes"
        ],
        "authors": [
            {
                "name": "LIU De-min",
                "org": "The Metabolic Hospital of Tianjin Medical University,Tianjin ,China"
            },
            {
                "name": "FANG Xian-feng",
                "org": "The Metabolic Hospital of Tianjin Medical University,Tianjin ,China"
            },
            {
                "name": "SUN Ying",
                "org": "The Metabolic Hospital of Tianjin Medical University,Tianjin ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "The Metabolic Hospital of Tianjin Medical University,Tianjin ,China"
            }
        ],
        "venue": "Journal of Tianjin Medical University",
        "year": 2006
    },
    "ibAIU63p": {
        "id": "ibAIU63p",
        "title": "Study on the Relationship between Homocysteine & N~(5,10)-methylenetetrahydrofolate Reductase and Diabetic Retinopathy",
        "abstract": "Objective: To study the relationship between plasma total homocysteine(tHcy), its metabolic correlating enzyme methylenetetrahydrofolate reductase(MTHFR) gene polymorphism, folate, and diabetic retinopathy. Methods: The plasma tHcy was measured by rHPLC in DR patients, folate level, plasma VitB12 were detected by radioimmunity. Genotype distribution of MTHFR 677CT and MTHFR 1298AC genotype distribution was analyzed by PCR-RFLP and then compared with the healthy group(control). Results: MTHFR C677T genotype frequency distribution and allele frequency in DR patients were statistically significant compared with the control group(P< 0.01). Patients with diabetic retinopathy had higher tHcy level than control subjects, and had lower folate level. DR patients who had MTHFR677CT mutation were associated with higher plasma tHcy level than those of the same genotype in the group(P< 0.05). There were no significant differences in MTHFR1298AC genotype distribution and allele frequency,neither were tHcy and folate level between mutant and wide types (P > 0.05). Conclusion: HHcy is a dangerous factor to DR. Plasma HCY level increase is ralated to the decrease of folate, MTHFR gene 677CT mutation is a main reason for HCY but MTHFR1298AC gene polymorphism is not related to DR.",
        "keywords": [
            "hyperhomocysteinemia methylenetetrahydrofolate reductase(NADPH2) diabetic retinopathy polymorphism(genetics)"
        ],
        "authors": [
            {
                "name": "LIU Demin",
                "org": "The Metabolic Hospital, Tianjin Medical University, Tianjin , China"
            },
            {
                "name": "FAN Xinping",
                "org": "The Metabolic Hospital, Tianjin Medical University, Tianjin , China"
            },
            {
                "name": "SUN Ying",
                "org": "The Metabolic Hospital, Tianjin Medical University, Tianjin , China"
            },
            {
                "name": "YU Demin",
                "org": "The Metabolic Hospital, Tianjin Medical University, Tianjin , China"
            },
            {
                "name": "ZHANG Jie",
                "org": "The Metabolic Hospital, Tianjin Medical University, Tianjin , China"
            }
        ],
        "venue": "Tianjin Medical Journal",
        "year": 2006
    },
    "v6zvTvfs": {
        "id": "v6zvTvfs",
        "title": "Construction and Identification of Eukaryotic pcDNA3.1/ CT- GFP-TOPO-Adiponectin Expression Vector",
        "abstract": "Objective: To construct the pcDNA3.1/CT -GFP-TOPO-Adiponectin expression vector. Methods: The encoding fragment of human Adiponectin gene was obtained from a recombinant plasmid pMD18-T/Adiponectin using PCR, then the gene was inserted into the vector pcDNA3.1/CT-GFP-TOPO after sequencing, which introduced into TOP10 competent cells in order to choose and sequence. Results: A 736 bp fragment was obtained by PCR clone after bloting and sequencing. The results were matching to the cDNA of human adiponectin, which accession of the gene bank was NM-004797. Conclusion: The eukaryotic pcDNA3.1/ CT-GFP-TOPO- Adipon ectin expression vector was constructed successfully.",
        "keywords": [
            "lipids genetic vectors plasmids green fluorescent proteins polymerase chain reaction"
        ],
        "authors": [
            {
                "name": "LIU Demin",
                "org": " Tianjin Medical University Metabolic Hospital, Tianjin ,China"
            },
            {
                "name": "DU Chunhong",
                "org": " Tianjin Medical University Metabolic Hospital, Tianjin ,China"
            },
            {
                "name": "SUN Ying",
                "org": " Tianjin Medical University Metabolic Hospital, Tianjin ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": " Tianjin Medical University Metabolic Hospital, Tianjin ,China"
            }
        ],
        "venue": "Tianjin Medical Journal",
        "year": 2007
    },
    "XCmhD22K": {
        "id": "XCmhD22K",
        "title": "Effect of Quercetin on Expression and Activity of Glucose-6-Phosphatase Gene",
        "abstract": "Objective:To study the effect of quercetin on expression and activity of glucose-6-phosphatase gene.Methods:The primary hepatocyte of rat was cultured in 25 mmol/L glucose and different concentrations of quercetin.Total RNA was extracted after 16 h incubated with 1640 medium containing glucose and quercetin.The levels of mRNA expression of glucose-6-phosphatase catalytic subunit(G6PC)and glucose-6-phosphate translocase(G6PT)were measured by semiquantitative RT-PCR.The enzymatic activity of glucose-6-phosphatase gene was determined by glucose dehydrogenase-coupled reaction.Results:The levels of G6PC and G6PT mRNA increased about two fold after incubated with 25 mmol/L glucose(P < 0.05).The enzymatic activities of G6PC and G6PT mRNA were inhibited by quercetin at different concentrations.Conclusion:Quercetin can inhibit the expression and activity of glucose-6-phosphatase gene induced by glucose in vitro.",
        "keywords": [
            "Wistar",
            "messenger hepatocytes rats",
            "quercetin glucose-6-phosphatase gene expression RNA"
        ],
        "authors": [
            {
                "name": "SUN Ying",
                "org": " Metabolism Disease Hospital,Tianjin Medical University,Tianjin ,China"
            },
            {
                "name": "LIU Demin",
                "org": " Metabolism Disease Hospital,Tianjin Medical University,Tianjin ,China"
            },
            {
                "name": "ZHAO Huiru",
                "org": " Metabolism Disease Hospital,Tianjin Medical University,Tianjin ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": " Metabolism Disease Hospital,Tianjin Medical University,Tianjin ,China"
            }
        ],
        "venue": "Tianjin Medical Journal",
        "year": 2007
    },
    "l2udemVq": {
        "id": "l2udemVq",
        "title": "Expression of human adiponectin gene in the baculovirus-insect cell expression system",
        "abstract": "Objective To investigate the expression of recombinant human adiponectin(ADPN) using baculovirus expression system in Sf 9 insect cell line.Methods PCR method was used to amplify human ADPN gene,and then the gene was inserted into plasmid pFastBacl.Recombinant plasmid was transformed into E.coli DH10Bac containing a shuttle vector,Bacmid.Recombinant shuttle vector Bacmid-ADPN was obtained by site-specific transposition and transfect Sf 9 cells.To identify the expressed product by SDS-PAGE、Western blot.Results Sf 9 cells infected by the recombinant baculovirus was observed for morphological changes.The Mw of recombinant protein was about 30 ku and Western blot proved that expressed protein could combine with ADPN polyclonal antibody.ConclusionHuman ADPN gene was successfully expressed in Sf 9 cells,and thus provided the material for studying its bioactivity and mechanism of action.",
        "keywords": [
            "expression",
            "baculovirus",
            "adiponectin",
            "insect cell"
        ],
        "authors": [
            {
                "name": "LIU De-min",
                "org": "Metabolic Disease Hospital,Tianjin Medical University,Tianjin ,China"
            },
            {
                "name": "DING Yu-jing",
                "org": "Metabolic Disease Hospital,Tianjin Medical University,Tianjin ,China"
            },
            {
                "name": "SUN Ying",
                "org": "Metabolic Disease Hospital,Tianjin Medical University,Tianjin ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Metabolic Disease Hospital,Tianjin Medical University,Tianjin ,China"
            }
        ],
        "venue": "Basic & Clinical Medicine",
        "year": 2007
    },
    "9ji1IWHU": {
        "id": "9ji1IWHU",
        "title": "The Relationship between PPAR γ and TLR4 Gene Polymorphisms and Type 2 Diabetes Mellitus",
        "abstract": "Objective: To explore the relationship among peroxisome proliferator-activated receptorγ(PPARγ) gene Pro12Ala and toll-like receptor 4(TLR4) gene Asp299Gly,Thr399Ile polymorphisms and type 2 diabetes mellitus(T2DM) in Tianjin area. Methods: To extract the genome DNA from 365 patients with T2DM and 95 healthy controls,and use polymerase chain reaction(PCR) to amply the objective fragment,then use DHPLC to detect the mutation. Results: There were no significant differences in genotype frequencies(P/A) of PPARγ gene Pro12Ala polymorphism between T2DM and control groups(0.074 0,27/365 and 0.031 6,3/95,respectively,P > 0.05). The genotypes of TLR4 gene Asp299Gly and Thr399Ile mutations were not found in the two groups. Conclusion: There were no significant correlation among PPARγ gene Pro12Ala,TLR4 gene Asp299Gly,Thr399Ile polymorphisms and type 2 diabetes mellitus in Tianjin area.",
        "keywords": [
            "diabetes mellitus",
            "genetic mutation chromatography",
            "Type 2 PPAR gamma polymorphism",
            "high pressure liquid Toll-like receptor 4 TIANJIN"
        ],
        "authors": [
            {
                "name": "HU Wenchao",
                "org": " Department of Laboratory,Metabolic Diseases Hospital,Tianjin Medical University,Tianjin ,China"
            },
            {
                "name": "LIU Demin",
                "org": " Department of Laboratory,Metabolic Diseases Hospital,Tianjin Medical University,Tianjin ,China"
            },
            {
                "name": "SUN Ying",
                "org": " Department of Laboratory,Metabolic Diseases Hospital,Tianjin Medical University,Tianjin ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": " Department of Laboratory,Metabolic Diseases Hospital,Tianjin Medical University,Tianjin ,China"
            }
        ],
        "venue": "Tianjin Medical Journal",
        "year": 2008
    },
    "2I7Jvsql": {
        "id": "2I7Jvsql",
        "title": "Evaluation of tumor drug resistance with Ku80 mRNA expression in human lung cancer",
        "abstract": "Objective:To study the different Ku80 mRNA expression in normal lung tissue group, lung cancer group(non small cell lung cancer) without chemotherapy, lung cancer group with multiple chemotherapy(n≥2),to evaluate the relationship of tumor drug resistance with Ku80 mRNA expression in human lung cancer.Methods:The lung tissue gene level of Ku80 mRNA was measured by reverse transcription polymerase chain reaction(RT-PCR) in 25 normal lung tissues, 51 lung cancer tissue,taking β-actin as inner reference.The data were analyzed by SPSS software.Results:Ku80 mRNA expression in normal lung tissue compared to lung cancer group without chemotherapy, lung cancer group with multiple chemotherapy(n≥2) had statistic significant meaning,respectively P<0.05 and P<0.01. Lung cancer group with multiple chemotherapy Ku80 mRNA expression was higher than lung cancer group with multiple chemotherapy(n≥2,P<0.05).Conclusion:The quantity of Ku80 mRNA expression could be an indicator to motoring lung cancer sensibility to chemotherapy. Therefore Ku80 mRNA expression amount may become a new useful indicators for predicting and assessing tumor chemotheraphy sensitivity.",
        "keywords": [
            "Chemotherapy",
            "Ku80 mRNA expression",
            "Lung cancer"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": ". The Second Affiliated Hospital of Jilin University,Changchun ,China"
            },
            {
                "name": "ZHENG Xiao-Wen",
                "org": ". The Second Affiliated Hospital of Jilin University,Changchun ,China"
            },
            {
                "name": "XU Ming-Yu",
                "org": ". The Second Affiliated Hospital of Jilin University,Changchun ,China"
            },
            {
                "name": "SU Zhen-Zhong",
                "org": ". The Second Affiliated Hospital of Jilin University,Changchun ,China"
            },
            {
                "name": "ZHI Yue",
                "org": ". The Second Affiliated Hospital of Jilin University,Changchun ,China"
            },
            {
                "name": "CHI Bao-Rong",
                "org": ". The Second Affiliated Hospital of Jilin University,Changchun ,China"
            }
        ],
        "venue": "Chinese Journal of Immunology",
        "year": 2006
    },
    "4QyE1n8G": {
        "id": "4QyE1n8G",
        "title": "The affection of Ku70 mRNA expression to tumor and drug resistance in human lung cancer",
        "abstract": "Objective:To investigate the relationship between Ku70 mRNA expression in non-neoplasm,in normal appearing pulmonary tissues,and in lung cancer tissue of pre-or post-chemotherapy and drug resistance.Methods:Ku70 mRNA in the lung tissues was measured by reverse transcription polymerase chain reaction (RT-PCR).The samples were extracted form 26 non-neoplasm, normal appearing pulmonary tissues and 56 lung cancer tissues.Results:Non-neoplasm, normal appearing pulmonary tissue group expressed Ku70 mRNA lower than lung cancer tissue group(P<0.01). And the lung cancer tissue with multiple chemotherapy (N≥2) expressed Ku70 mRNA more than the lung cancer tissue without chemotherapy (P<0.01).Conclusion:Ku70 mRNA expression may concern with chemotherapy resistance in human lung cancer, which is up-regulated following chemotherapy.",
        "keywords": [
            "Ku70 mRNA expression",
            "Chemotherapy",
            "Lung cancer"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": ".The Second Hospital of Jilin University,Changchun ,China"
            },
            {
                "name": "LI Ya-Rong",
                "org": ".The Second Hospital of Jilin University,Changchun ,China"
            },
            {
                "name": "SU Zhen-Zhong",
                "org": ".The Second Hospital of Jilin University,Changchun ,China"
            },
            {
                "name": "ZHENG Xiao-Wen",
                "org": ".The Second Hospital of Jilin University,Changchun ,China"
            },
            {
                "name": "ZHANG Yun-Xia",
                "org": ".The Second Hospital of Jilin University,Changchun ,China"
            },
            {
                "name": "ZHI Yue",
                "org": ".The Second Hospital of Jilin University,Changchun ,China"
            }
        ],
        "venue": "Chinese Journal of Immunology",
        "year": 2007
    },
    "Lc0fsQKo": {
        "id": "Lc0fsQKo",
        "title": "A case of moxifloxacin in the treatment of COPD complicated with pulmonary infection",
        "abstract": "",
        "keywords": [
            "moxifloxacin",
            "pulmonary infection",
            "chronic obstructive pulmonary disease"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": ". Department of Respiratory Medicine,the Second Hospital of Jilin University,Changchun ,China"
            },
            {
                "name": "DONG Chun-ling",
                "org": ". Department of Respiratory Medicine,the Second Hospital of Jilin University,Changchun ,China"
            }
        ],
        "venue": "Chinese Journal of Practical Internal Medicine",
        "year": 2009
    },
    "4eqbRNia": {
        "id": "4eqbRNia",
        "title": "Effect of 12(S)-HETE on the p27~(kip1) expression in rat mesangial cells and glomeruli",
        "abstract": "Objective:To investigate the effect of 12(S)-HETE on the p27kip1 expression in mesangial cells and glomeruli.Methods:Mesangial cells were exposed to 12(S)-HETE.12(S)-HETE was infused to rats by osmotic mini-pump.Total protein content measurement for cell hypertrophy,RT-PCR for mRNA expression and Western blot for protein expression were performed respectively.Results:12(S)-HETE stimulation induced mesangial cell hypertrophy and p27kip1 protein expression,but not p27kip1 mRNA expression.Furthermore,p27kip1 mRNA and protein expression in the glomeruli were significantly increased by 12(S)-HETE stimulation using osmotic mini-pump.Conclusion:12(S)-HETE plays an important role in the pathogenesis of glomerular cell hypertrophy and senescence through upregulation of p27kip1 expression.",
        "keywords": [
            "12(S)-HETE",
            "Mesangial cell",
            "Glomeruli",
            "p27kip1"
        ],
        "authors": [
            {
                "name": "CUI Ying-Chun",
                "org": ".Second Hospital of Jilin University,Changchun ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": ".Second Hospital of Jilin University,Changchun ,China"
            },
            {
                "name": "LIU Qing-Xin",
                "org": ".Second Hospital of Jilin University,Changchun ,China"
            },
            {
                "name": "GUO Qiao-Yan",
                "org": ".Second Hospital of Jilin University,Changchun ,China"
            },
            {
                "name": "WU Man",
                "org": ".Second Hospital of Jilin University,Changchun ,China"
            },
            {
                "name": "ZHANG Dong-Mei",
                "org": ".Second Hospital of Jilin University,Changchun ,China"
            },
            {
                "name": "MIAO Li-Ning",
                "org": ".Second Hospital of Jilin University,Changchun ,China"
            },
            {
                "name": "XU Zhong-Gao",
                "org": ".Second Hospital of Jilin University,Changchun ,China"
            }
        ],
        "venue": "Chinese Journal of Immunology",
        "year": 2009
    },
    "xQOMbDN4": {
        "id": "xQOMbDN4",
        "title": "Expression of RBM6-RBM5 transcription-induced chimera in tumor cells and tissues",
        "abstract": "Objective: To determine the existence of RBM6-RBM5 chimera and study its relationship with oncogenesis. Methods: Ten cell lines including GLC-20, MDA. MB. 231, Jurkat, TF-I, MCF-7, HeIa, BT-474, A431, K562 and Raji ; several cDNAs from tumor tissues including lung, ovary, skeletal, skin, spleen, uterus, heart, bone, brain, lymph node, pancreas, prostate, testis and their normal controls and 5 breast cancer tissues were collected for the study. Nested PCR was used to identify the existence and expression level of RBM6-RBM5 chimera. QPCR was used to determine the RBM6, RBM5 gene expression level in chimeric positive and negative tumor tissues. Results: RBM6-RBM5 chimera was identified in MDA, MB, 231 cell line, which lacked exons 20, 21 of RBM6 and exon 1 of RBM5. The chimeric expression was only observed on 10 tumor cell lines and tissues, among some specific tumor types, the chimeric expression was associated with elevated levels of RBM6 and RBM5 mRNA. Conclusion: RBM6 mRNA experiences altered co-transcriptional gene regulation in certain cancers. RBM6-RBM5 transcription-induced chimerism might be a process that is linked to the tumor-associated increased transcriptional activity of the RBM6 and RBM5 genes, and this chimera might be a new marker for tumor prediction.",
        "keywords": [
            "RNA binding motif protein",
            "Transcription-induced chimera",
            "Tumor cells",
            " cultured"
        ],
        "authors": [
            {
                "name": "Ke Wang",
                "org": "Jilin University(Jilin University),Changchun,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Jilin University(Jilin University),Changchun,China"
            },
            {
                "name": "LI Ran-wei",
                "org": "Jilin University(Jilin University),Changchun,China"
            }
        ],
        "venue": "Journal of Jilin University(Medicine Edition)",
        "year": 2009
    },
    "2s5AmSKy": {
        "id": "2s5AmSKy",
        "title": "The Design and Realization of the Digital Audio Play System",
        "abstract": "For the shortage of the traditional simulated audio system,a kind of digital audio play system based on ARM embedded microprocessor is designed and realized.This system can storage and play audio format of WAV and MP3 by timer interrupt.The design project and part program of the system are given in the paper.",
        "keywords": [
            "digital audio",
            "ARM microprocessor",
            "decoder",
            "interrupt"
        ],
        "authors": [
            {
                "name": "LV Ming",
                "org": " Nanjing North Information Industry Group Ltd.,Nanjing,Jiangsu,,China"
            },
            {
                "name": "ZHANG Jie",
                "org": " Nanjing University of Science and Technology,Nanjing,Jiangsu,,China"
            }
        ],
        "venue": "Journal of Jingchu University of Technology",
        "year": 2009
    },
    "V9hGcxWF": {
        "id": "V9hGcxWF",
        "title": "Fault Detection of Networked Control Systems with Output Delays",
        "abstract": "Considering a class of networked control systems with long time delays,the fault detection is carried out supposing that the output delays are present between the sensor and the controller.The fault observer with delay compensation is constructed,and the state estimate error equation is given.Based on the theory of discrete switching systems,a linear matrix inequality is given to express the stability condition of this observer.When the system is normal,if the given inequality condition is satisfied,the observer system is asymptotically stable.When a fault is present,the observer residual can change rapidly and detect the occurrence of the fault.An illustrative example shows the effectiveness of the proposed method.",
        "keywords": [
            "observer",
            "output delay",
            "fault detection",
            "networked control system"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Institute of Automation,Nanjing University of Science and Technology, Nanjing ,China"
            },
            {
                "name": "BO Yu-ming",
                "org": "Institute of Automation,Nanjing University of Science and Technology, Nanjing ,China"
            },
            {
                "name": "HU Wei-li",
                "org": "Institute of Automation,Nanjing University of Science and Technology, Nanjing ,China"
            }
        ],
        "venue": "Control Engineering of China",
        "year": 2009
    },
    "a6LMZ4wU": {
        "id": "a6LMZ4wU",
        "title": "Integrated Chi-square fault detection of networked control systems based on Kalman filter with delay compensation",
        "abstract": "Considering a class of networked control systems with time delays, a novel method was proposed to design Kalman filters with delay compensation, and it was used to estimate the state of the system. Through studying the delay characteristics, a discrete-time Kalman filter formula of the networked control systems was derived by using the variational method, and a specific optimal linear recursive filtering algorithm was given. And in the fault detection, a new Integrated Chi-square Test was proposed. Finally, a simulation example was given to verify the effectiveness of the proposed Kalman filter and Integrated Chi-square Test.",
        "keywords": [
            "Chi-square test",
            "Delay compensation",
            "Fault detection",
            "Kalman filter",
            "Networked control system"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Nanjing University of Science and Technology(Nanjing University of Science and Technology,Nanjing Univ. of Sci. and Technol.,Nanjing Univ. of Sci. and Technology,NUST),Nanjing,China"
            },
            {
                "name": "BO Yu-ming",
                "org": "Nanjing University of Science and Technology(Nanjing University of Science and Technology,Nanjing Univ. of Sci. and Technol.,Nanjing Univ. of Sci. and Technology,NUST),Nanjing,China"
            }
        ],
        "venue": "Xitong Fangzhen Xuebao / Journal of System Simulation",
        "year": 2009
    },
    "g7XXYHq7": {
        "id": "g7XXYHq7",
        "title": "Decentralized robust fault-tolerant control for large-scale systems with time-delays in interconnection",
        "abstract": "A method of decentralized robust fault-tolerant control is presented for large-scale systems with time-delays in interconnection.The purpose of the method is to make the system remain stable,for sensor or actuator failures as well as uncertainties. Based on Lyapunov theory,the sufficient conditions of the systems with fault-tolerance under sensor failures and the design procedure of the controller are given.And the result is generalized to the systems under actuator failures.At the end of this paper,an illustrative example is given to demonstrate the correctness of the proposed method,and the result of the example is analyzed.",
        "keywords": [
            "state-feedback",
            "robustness",
            "fault-tolerant",
            "time-delay"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": " Department of Automation,Nanjing University of Science and Technology,Nanjing ,China"
            },
            {
                "name": "BO Yu-ming",
                "org": " Department of Automation,Nanjing University of Science and Technology,Nanjing ,China"
            }
        ],
        "venue": "Computer Engineering and Applications",
        "year": 2010
    },
    "QV7rRVBy": {
        "id": "QV7rRVBy",
        "title": "Handwritten Digital Recognition Based on Wavelet Transform and ART Neural Networks",
        "abstract": "Because that wavelet transform can effectively extract the characters, the Adaptive Resonance Theory (ART) Neural Networks has a good learning ability. This paper combines the two aspects to recognize handwritten digits by using wavelet transform to extract feature and Adaptive Resonance Theory (ART) Neural Networks for Classification. The result of experiment shows high recognition rate, which indicates that the method can effectively classify handwritten digits and be put into practical use.",
        "keywords": [
            "Handwritten digital recognition Wavelet transform ART neural networks"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Department of management, Xi'an University of Arch. & Tech. , Xi'an , China"
            },
            {
                "name": "HUANG Guang-qiu",
                "org": "Department of management, Xi'an University of Arch. & Tech. , Xi'an , China"
            },
            {
                "name": "FENG Jun-hong",
                "org": "Department of management, Xi'an University of Arch. & Tech. , Xi'an , China"
            }
        ],
        "venue": "Microcomputer Applications",
        "year": 2006
    },
    "ivGeTVpU": {
        "id": "ivGeTVpU",
        "title": "Research and Implementation of Converting PPT Files into Word Files Based on VBA",
        "abstract": "On the basis of researching the Word VBA and the Powerpoint VBA,this paper deeply studies the Word object and the Powerpoint object,puts forward the perfect solution to convert PPT files into Word files,and researches and develops the corresponding conversion system.",
        "keywords": [
            "Word",
            "VBA",
            "Conversion",
            "PPT"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Information Science Department,Sontan School,Guangzhou University,Zengcheng,Guangzhou ;School of Computer Science and Technology,Xidian University,Xi'an ,China"
            },
            {
                "name": "FENG Jun-hong",
                "org": "Information Science Department,Sontan School,Guangzhou University,Zengcheng,Guangzhou "
            }
        ],
        "venue": "Microcomputer Applications",
        "year": 2009
    },
    "VPwt3V0i": {
        "id": "VPwt3V0i",
        "title": "Dynamic particle swarm optimization based on dynamic distance threshold and regeneration mechanism",
        "abstract": "Through introducing dynamic distance threshold to standard PSO,two kinds particle between inside and outside the best location were divided into,the former executed concentrated search,the latter did scatter search,which reasonably ba-lanced the both contradiction.This result in that under the circumstance of keeping fundamental stable condition in particle diversity,convergence speed was improved.By regenerating the dead particle without any contribution,this both might suppress effectively reductions of the particle diversity,and could cause the search to jump out local optimization.The simulating experiment have certified that the algorithm can improve not only the convergence but also the particle diversity.",
        "keywords": [
            "dynamic distance threshold",
            "diversity",
            "convergence",
            "dead particle",
            "PSO(particle swarm optimization)"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Dept.of Information Science,Sontan College,Guangzhou University,Guangzhou ,China;School of Computer Science & Technology,Xidian University,Xi'an ,China"
            },
            {
                "name": "FENG Jun-hong",
                "org": "Dept.of Information Science,Sontan College,Guangzhou University,Guangzhou ,China"
            }
        ],
        "venue": "Application Research of Computers",
        "year": 2009
    },
    "XJI5Pg2I": {
        "id": "XJI5Pg2I",
        "title": "The Parellel Particle Swarm Optimization Based on Dynamic Distance Threshold",
        "abstract": "Through introducing dynamic distance threshold to standard PSO,the particles are divided into three categories of the vicinity of the best position,the vicinity of the average position and the other position,which are formed three Subspecies. The first category execute concentrated search,the second category do general search and the third category do scatter search,which reasonably balance the contradiction of coarse search and detailed search. This bring about that convergence speed is improved under the circumstance of keeping fundamental stable condition in particle diversity. The parallel algorithm is used to speed up calculating speed,to keep the particle diversity and to jump out local optimization. The simulating experiments have certified that the algorithm can improve not only the convergence but also the particle diversity.",
        "keywords": [
            "parallel",
            "dynamic distance threshold",
            "diversity",
            "optimization",
            "PSO"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": " Information Science and Engineering Department,Sontan College of Guangzhou University,Zengcheng ,China; School of Computer Science and Technology,Xidian University,Xi′an ,China"
            },
            {
                "name": "FENG Jun-hong",
                "org": " Information Science and Engineering Department,Sontan College of Guangzhou University,Zengcheng ,China"
            }
        ],
        "venue": "Microelectronics & Computer",
        "year": 2010
    },
    "k9262of8": {
        "id": "k9262of8",
        "title": "Synthesis and characterization of a new zinc phosphate with 16-ring channels: Zn3PO4(HPO4)3·C6N3H18",
        "abstract": "A new open-framework zinc phosphate, Zn 3 PO 4 (HPO 4 ) 3 · C 6 N 3 H 18 (denoted FJ-11), was synthesized under solvothermal conditions in the presence of 1-(2-aminoethyl)piperazine as structure-directing agent. Its structure was determined by single-crystal X-ray diffraction and further characterized by FTIR, elemental analysis, ICP analysis, powder X-ray diffraction and thermogravimetric analysis. The compound crystallized in the triclinic space group, P -1, with a =8.2807(2) Å, b =9.13750(10) Å, c =13.3463(2) Å, α =83.7700(10)°, β =84.4460(10)°, γ =78.0250(10)°, V =979.17(3) Å 3 , Z =2. The structure consists of ZnO 4 , PO 4 and HPO 4 tetrahedra with shared corners, forming intersecting three-dimensional channels. The triply protonated 1-(2-aminoethyl)piperazine molecules reside in the large 16-ring channels and interact with the inorganic framework by extensive hydrogen bonds. Keywords Open-framework Crystal structure Zinc phosphate Solvothermal synthesis 16-Ring channels Zeolites",
        "keywords": [
            "16-Ring channels",
            "Crystal structure",
            "Open-framework",
            "Solvothermal synthesis",
            "Zeolites",
            "Zinc phosphate"
        ],
        "authors": [
            {
                "name": "Zhi-En Lin",
                "org": "Coordination and Hydrothermal Chemistry Group, State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, 155 West Yangqiao Road, Fuzhou, Fujian 350002, China"
            },
            {
                "name": "Qing-Xin Zeng",
                "org": "Coordination and Hydrothermal Chemistry Group, State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, 155 West Yangqiao Road, Fuzhou, Fujian 350002, China"
            },
            {
                "name": "Jie Zhang",
                "org": "Coordination and Hydrothermal Chemistry Group, State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, 155 West Yangqiao Road, Fuzhou, Fujian 350002, China"
            },
            {
                "name": "Guo-Yu Yang",
                "org": ""
            }
        ],
        "venue": "Microporous and Mesoporous Materials",
        "year": 2003
    },
    "ubjkfTR3": {
        "id": "ubjkfTR3",
        "title": "Synthesis, structure and properties of a neutral zincophosphate monomer decorated with 2,2′-bipyridine ligands",
        "abstract": "A neutral zincophosphate monomer [Zn(2,2 ′ -bipy)] 2 (H 2 PO 4 ) 4 has been synthesized under hydrothermal condition in the presence of 2,2 ′ -bipyridine ligands. The structure consists of a 4-membered ring formed by vertex-sharing ZnO 3 N 2 square pyramids and H 2 PO 4 tetrahedra, with two H 2 PO 4 groups hanging from the zinc atoms. This compound exhibits intense photoluminescence upon photoexcitation at 388 nm.",
        "keywords": [
            "Hybrid materials",
            "Zinc phosphate",
            "Hydrothermal synthesis",
            "Crystal structure",
            "Luminescence"
        ],
        "authors": [
            {
                "name": "Zhi-En Lin",
                "org": "Coordination and Hydrothermal Chemistry Group, State Key Laboratory of the Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, Fujian 350002, China"
            },
            {
                "name": "Jie Zhang",
                "org": "Coordination and Hydrothermal Chemistry Group, State Key Laboratory of the Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, Fujian 350002, China"
            },
            {
                "name": "Shou-Tian Zheng",
                "org": "Coordination and Hydrothermal Chemistry Group, State Key Laboratory of the Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, Fujian 350002, China"
            },
            {
                "name": "Guo-Yu Yang",
                "org": ""
            }
        ],
        "venue": "Inorganic Chemistry Communications",
        "year": 2003
    },
    "vYfD1jMp": {
        "id": "vYfD1jMp",
        "title": "Synthesis and characterization of a new hybrid zinc phosphite (4,4′-bipy)[Zn(HPO3)]2 with a pillared layer structure",
        "abstract": "A new inorganic–organic hybrid solid, (4,4 ′ -bipy)[Zn(HPO 3 )] 2 (4,4 ′ -bipy=4,4 ′ -bipyridine), has been hydrothermally synthesized in the presence of 4,4 ′ -bipy ligand. Its structure was determined by single-crystal X-ray diffraction and further characterized by FTIR, elemental analysis, ICP analysis, powder X-ray diffraction, thermogravimetric analysis and fluorescent spectrum. It crystallized in the monoclinic space group, P 2 1 / c , with a =9.741(2), b =7.4423(16), c =10.271(2) Å, β =100.038(4)°, V =733.3(3) Å 3 , Z =2. The structure consists of neutral sheets of zinc phosphite which is pillared through 4,4 ′ -bipy ligands to generate a 3D framework. The compound shows relatively high thermal stability and exhibits intense photoluminescence upon photo-excitation at 362 nm.",
        "keywords": [
            "Zinc phosphite",
            "Crystal structure",
            "Hybrid solid",
            "Fluorescent emission",
            "Open-framework"
        ],
        "authors": [
            {
                "name": "Zhi-En Lin",
                "org": "Coordination and Hydrothermal Chemistry Group, State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, 155 West Yangqiao Road, Fuzhou, Fujian 350002, PR China"
            },
            {
                "name": "Jie Zhang",
                "org": "Coordination and Hydrothermal Chemistry Group, State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, 155 West Yangqiao Road, Fuzhou, Fujian 350002, PR China"
            },
            {
                "name": "Shou-Tian Zheng",
                "org": "Coordination and Hydrothermal Chemistry Group, State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, 155 West Yangqiao Road, Fuzhou, Fujian 350002, PR China"
            },
            {
                "name": "Guo-Yu Yang",
                "org": ""
            }
        ],
        "venue": "Microporous and Mesoporous Materials",
        "year": 2004
    },
    "85eOWVu2": {
        "id": "85eOWVu2",
        "title": "K7{(BO3)Mn[B12O18(OH)6]}·H2O: first manganese borate based on covalently linked B12O18(OH)6 clusters and BO3 units via Mn2+ cations",
        "abstract": "A novel manganese oxyborate, K 7 {(BO 3 )[B 12 O 18 (OH) 6 ]} · H 2 O ( 1 ), which is the first example showing the edge-sharing between boron and transition metal, has been solvothermally synthesized. The structure consists of [B 12 O 20 (OH) 4 ] and [BO 3 ] which are linked through unusual MnO 5 polyhedron via vertexes and edges. This compound exhibits NLO properties and the intensity of the green light (frequency-doubled output: λ =532 nm) produced by 1 is as large as that of KDP. Keywords Manganese Borate NLO properties",
        "keywords": [
            "Borate",
            "Manganese",
            "NLO properties"
        ],
        "authors": [
            {
                "name": "Hong-Xia Zhang",
                "org": "Coordination and Hydrothermal Chemistry Group, State Key Laboratory of Structural Chemistry, Fujian Institution of Research on the Structure of Matter, Chinese Academy of Science, Fuzhou, Fujian 350002, China"
            },
            {
                "name": "Jie Zhang",
                "org": "Coordination and Hydrothermal Chemistry Group, State Key Laboratory of Structural Chemistry, Fujian Institution of Research on the Structure of Matter, Chinese Academy of Science, Fuzhou, Fujian 350002, China"
            },
            {
                "name": "Shou-Tian Zheng",
                "org": "Coordination and Hydrothermal Chemistry Group, State Key Laboratory of Structural Chemistry, Fujian Institution of Research on the Structure of Matter, Chinese Academy of Science, Fuzhou, Fujian 350002, China"
            },
            {
                "name": "Guo-Yu Yang",
                "org": ""
            }
        ],
        "venue": "Inorganic Chemistry Communications",
        "year": 2004
    },
    "1PfAFjmR": {
        "id": "1PfAFjmR",
        "title": "Synthesis and characterization of Ga2(phen)(HPO4)3: a new 2D hybrid gallium phosphate with neutral framework",
        "abstract": "A new layered inorganic–organic hybrid gallium phosphate, Ga 2 (phen)(HPO 4 ) 3 (phen=1,10-phenanthroline), has been hydrothermally synthesized and characterized by single crystal X-ray diffraction, FTIR, elemental analysis, ICP, power X-ray diffraction and thermogravimetric analysis. This compound crystallizes in the triclinic system, space group P -1 (No. 2), a =7.7730(6) Å, b =11.7968(10) Å, c =12.1458(9) Å, α =114.089(2)°, β =102.310(2)°, γ =102.905(2)°, V =931.28(13) Å 3 , Z =2. The structure is built from strictly alternating GaO 4 N 2 octahedra, GaO 4 tetrahedra and HPO 4 tetrahedra through their vertices, forming a neutral layered architecture grafted with phen ligands. The adjacent sheets are stacked in an AAAA sequence along [0 0 1] direction and held together by strong π–π interactions. Keywords Gallium phosphate Layer Hybrid solid Hydrothermal synthesis Crystal structure",
        "keywords": [
            "Crystal structure",
            "Gallium phosphate",
            "Hybrid solid",
            "Hydrothermal synthesis",
            "Layer"
        ],
        "authors": [
            {
                "name": "Zhi-En Lin",
                "org": "Coordination and Hydrothermal Chemistry Group, State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, Fujian 350002, PR China"
            },
            {
                "name": "Jie Zhang",
                "org": "Coordination and Hydrothermal Chemistry Group, State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, Fujian 350002, PR China"
            },
            {
                "name": "Shou-Tian Zheng",
                "org": "Coordination and Hydrothermal Chemistry Group, State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, Fujian 350002, PR China"
            },
            {
                "name": "Guo-Yu Yang",
                "org": "State Key Laboratory of Structural Chemistry, Fuzhou(Chinese Academy of Sciences),Fuzhou,China"
            }
        ],
        "venue": "Microporous and Mesoporous Materials",
        "year": 2004
    },
    "BcUqLvfX": {
        "id": "BcUqLvfX",
        "title": "Syntheses and structures of two new 3D open-framework germanates constructed from Ge9O18(OH)4 clusters",
        "abstract": "Two new open-framework germanates, [Cd 2 (C 2 N 2 H 8 ) 3 ][Ge 9 O 18 (OH) 4 ] ( 1 ) and (C 8 N 4 H 26 )[Ge 9 O 18 (OH) 4 ] ( 2 ), have been hydrothermally synthesized and characterized by single-crystal X-ray diffraction. Compound 1 crystallizes in the orthorhombic space group, P bca, with a = 14.318(3), b = 13.106(3), c = 14.580(3) Å, V = 2736.0(9) Å 3 , Z = 4. The compound is the first organically templated cadmium germanate. The structure of 1 is constructed from two distinct motifs, a body-centered [Ge 9 O 18 (OH) 4 ] cluster and a cadmium complex [Cd 2 (C 2 N 2 H 8 ) 3 O 6 ], which integrate to generate a 3D architecture with neutral framework. The structures of 2 is closely related to that of 1 and has identical Ge 9 O 18 (OH) 4 clusters. It crystallizes in the orthorhombic space group, P bca, with a = 14.158(3), b = 13.213(3), c = 14.553(3) Å, V = 2722.5(9) Å 3 , Z = 4. The connectivity between the Ge 9 clusters result in a 3D open-framework structure. The quadruply protonated N , N ′-bis(3-aminopropyl)ethylene diamine molecules are located in the free voids and interact with the macroanionic inorganic framework by extensive hydrogen bonds. Keywords Open framework Germanate Cluster Hydrothermal synthesis Crystal structure 1 Introduction Open-framework inorganic solids attracted considerable attention in the past decades due to their rich structural chemistry and potential application in ion-exchange, separation and catalysis [1] . Zeolites (aluminosilicates) are the most well-known family of such materials. Following the discovery of organically templated germanates in 1991 [2,3] , great efforts have been devoted to the pursuit of novel open-framework structures within this system [4–14] . Open-framework germanates are interesting for several reasons. First, in contrast to silicon, which is usually tetrahedrally coordinated, germanium can exist in a more variable and expanded coordination environment due to the relatively large Ge/O radius ratio. This implies that a large number of novel structures can be potentially accessed. Second, germanates show great tendency to form extended structures with odd-membered rings. For example, open-framework germanates with 3-, 5-, 7- and 9-rings have been synthesized and characterized [15–18] . Finally, the capacity of germanium to form cluster aggregates offers great opportunities for the design of open frameworks with large pores and channel sizes. Yaghi et al. have reported Ge 7 O 14.5 F 2 · [(CH 3 ) 2 NH 2 ] 3 (H 2 O) 0.86 (ASU-12) as a genuinely porous germanate with large 16-membered-ring windows [19] . The structure is constructed from Ge 7 clusters and exhibits remarkable ion-exchange properties reminiscent of aluminosilicate zeolites. By using a different organic amine as structure-directing agent, a material (ASU-16) with the same building units, but with a larger 24-ring channels and much lower framework density (8.6 Ge atoms per 1000 Å 3 ), has been prepared in similar synthesis conditions [9] . Zhao et al. have reported the synthesis and structure of another 24-membered-ring germanate (FDU-4), which is condensed from Ge 9 clusters under solvothermal conditions [20] . The aim of our work is to construct new open frameworks from germanium-oxide clusters, and we have isolated several new compounds in this system [21] . Here, we report two new germanates [Cd 2 (C 2 N 2 H 8 ) 3 ][Ge 9 O 18 (OH) 4 ] ( 1 ) and (C 8 N 4 H 26 )[Ge 9 O 18 (OH) 4 ] ( 2 ), which consist of Ge 9 clusters as building units connected though common vertices to form 3D framework. 2 Experimental 2.1 Synthesis and initial characterization In a typical synthesis for 1 , 0.15 g of GeO 2 was dispersed in a mixed solution of 0.5 ml of H 2 O and 1.33 ml of ethylene glycol, and then 0.77 ml of ethylenediamine was dropwise added to get a clear solution. To this mixture, 0.082 g of CdCl 2 · 2H 2 O was finally added and homogenized for 30 min. The resulting mixture of the composition GeO 2 :ethylenediamine:CdCl 2 · 2H 2 O:H 2 O:ethylene glycol in a molar ratio of 1:8:0.25:25:15 was sealed in a Teflon-lined steel autoclave, heated at 170 °C for 7 days and then cooled to room temperature. The product was recovered by filtration, washed thoroughly with distilled water, dried at room temperature, and then colorless prism-like crystals were obtained (65% yield based on germanium). The ICP analysis shows that the compound contains 44.86 wt% Ge and 15.13 wt% Cd, indicating a Ge:Cd ratio of 9:2. Elemental analysis results of the bulk product are consistent with the stoichiometry of 1 . Anal. found: C, 5.24%; H, 1.51%; N, 5.92%. Calcd: C, 5.09%; H, 1.71%; N, 5.94%. IR (KBr, cm −1 ) for 1 : 3318m, 3267m, 3161w, 2920m, 2457w, 1583m, 1485w, 1458w, 1283m, 1189w, 1110m, 1038m, 950w, 780s, 728s, 703s, 581s, 522s, 482s, 416m. In a typical synthesis for 2 , a mixture of GeO 2 (0.15 g), H 2 O (0.5 ml), ethylene glycol (1.33 ml) and N , N ′-bis(3-aminopropyl)ethylene diamine (2.2 ml) in a molar ratio of 1:25:15:8 was stirred under ambient conditions. The resulting gel, with a pH of ∼9, was sealed in a Teflon-lined steel autoclave and heated in 170 °C for 7 days and then cooled to room temperature. The resulting product, which contained colorless prism-like crystals, was recovered by filtration, washed with distilled water and dried in air (54% yield based on germanium). Elemental analysis was carried out to verify the organic content. Anal. found: C, 8.00%; H, 2.57%; N, 4.61%. Calcd: C, 8.09%; H, 2.55%; N, 4.72%. IR (KBr, cm −1 ) for 2 : 3024w, 1600m, 1506m, 1475m, 1285m, 1213m, 779vs, 717s, 583s, 492s, 417m. Preliminary thermogravimetric analyses of compound 1 and 2 were carried out under O 2 atmosphere with a heating rate of 10 °C/min −1 from 40 to 700 °C. For 1 , a two-step weight loss of 15.78% was observed in the range between 360 and 670 °C, corresponding to the departure of ethylenediamine molecules (observed: 13.01%; expected: 12.75%) and the dehydration process (observed: 2.77%; expected: 2.55% weight loss for two water molecules per formula unit). The post residue is CdO and GeO 2 . For 2 , a total weight loss of 17.24% was observed in the range between 260 and 680 °C, due to the release of organic amines (expected: 14.67%) from the structure and the partial dehydration process (expected: 6.06% weight loss for four water molecules per formula unit). The final product is amorphous GeO 2 . 2.2 Crystal structure determination A suitable single crystal of as-synthesized compounds with the dimensions of 0.29 × 0.11 × 0.06 mm for 1 and 0.33 × 0.20 × 0.16 mm for 2 was carefully selected under an optical microscope and glued to a thin glass fiber with epoxy resin, respectively. Crystal structure determination by X-ray diffraction was performed on a Siemens SMART CCD diffractometer with graphite-monochromated MoKα ( λ = 0.71073 Å) radiation in the ω and ϕ scanning mode at room temperature. Both structures were solved by direct methods and refined on F 2 by full-matrix least-squares methods using the SHELX97 program package [22,23] . The crystal structure of 1 was solved in the orthorhombic space group P bca (No. 61). The cadmium and germanium atoms were first located, and the carbon, nitrogen, and oxygen atoms were found in the final difference Fourier map. The cadmium atom is disorder over two positions, with the occupancies of 90% and 10%, respectively. The H atom were positioned at idealized geometry and refined using a riding model, except the hydrogen attached to O(10) and N(1) atoms. All non-hydrogen atoms were refined anisotropically. Experimental details for the structure determination are presented in Table 1 . The coordinates of all non-H atoms are given in Table 2 . Selected bond distances are listed in Table 3 . The determination of the crystal structure of 2 followed the same procedure as outlined for 1 with location of the Ge atoms from direct methods (space group P bca; No. 61), and subsequent difference Fourier analysis in order to locate the carbon, nitrogen, and oxygen atoms. There is one protonated N , N ′-bis(3-aminopropyl)ethylene diamine per formula, which is disordered within the cavities of the structure. The hydrogen atoms were positioned at idealized geometry and all the framework atoms were refined anisotropically. Experimental details for the structure determination are presented in Table 1 . The coordinates of all non-H atoms are given in Table 4 . Selected bond distances are listed in Table 5 . 3 Results 3.1 Crystal structure of [Cd 2 (C 2 N 2 H 8 ) 3 ][Ge 9 O 18 (OH) 4 ] 1 The asymmetric unit of 1 consists of 23 non-hydrogen atoms, as shown in Fig. 1 . There are one crystallographically distinct cadmium atom and five unique germanium atoms. The cadmium atom is octahedrally coordinated, bonded to three oxygen atoms [Cd–O (ave.) 2.399 Å] and three nitrogen atoms [Cd–N (ave.) 2.260 Å] from ethylenediamine ligands. Of the five independent Ge atoms, Ge(1) and Ge(2) atoms are tetrahedrally coordinated, with the Ge–O distances in the range 1.715(7)–1.773(7) Å (ave. 1.743 Å) and the O–Ge–O angles in the range of 106.4(3)–113.2(3)°. Ge(3) and Ge(4) atoms are coordinated to five oxygen atoms, with the Ge–O bond distances varying from 1.747(8) to 2.018(7) Å (ave. 1.836 Å). Ge(5) is located at the inversion center and is octahedrally coordinated, with Ge–O distances between 1.880(7) and 1.885(6) Å (ave. 1.883 Å). These geometric parameters are in accord with those observed for open-framework germanates containing Ge 9 O 18 (OH) 4 clusters [24–27] . Assuming the usual valence of Cd, Ge, and O atoms to be +2, +4, and −2, respectively, the framework stoichiometry of [CdGe 4.5 O 11 ] creates a net charge of −2, which is needed to be balanced. Bond valence sum values indicate that O(10) and O(11) are hydroxyl groups. The structure of 1 is constructed from two distinct motifs, a body-centered [Ge 9 O 18 (OH) 4 ] cluster and a cadmium complex [Cd 2 (C 2 N 2 H 8 ) 3 O 6 ], which integrate to generate a 3D architecture with neutral framework ( Fig. 2a and b ). As shown in Fig. 3a , the Ge 9 building block is condensed from four GeO 4 tetrahedra, four GeO 4 (OH) trigonal bipyramids, and one GeO 6 octahedron. The GeO 6 occupies the center of the cluster and links the four GeO 4 and four GeO 4 (OH) through doubly bridging oxygen atoms and tri-bridging oxygen atoms. Each of such building units is connected to eight adjacent Ge 9 units in a body-centered manner to form a three-dimensional framework. The second structural building block is a cadmium complex [Cd 2 (C 2 N 2 H 8 ) 3 O 6 ] containing two types of ethylenediamine molecules, one acts as chelating ligand and protrudes into the 8-ring channel and the other serves as a bridge to connect two symmetry-related cadmium atoms ( Fig. 3b ). In addition to the three nitrogen donors from the ethylenediamine ligands, each cadmium atom is connected to the germanate framework through O(7), O(9) and O(10) atoms. 3.2 Crystal structure of (C 8 N 4 H 26 )[Ge 9 O 18 (OH) 4 ] 2 As seen in Fig. 4 , the asymmetric unit of 2 contains five crystallographically distinct germanium atoms, which have three different coordination numbers. Ge(1) and Ge(2) each has typical tetrahedral coordination, with the Ge–O distances in the range 1.721(4)–1.781(4) Å (ave. 1.748 Å) and the O–Ge–O angles in the range of 105.38(19)–112.6(2)°. Ge(3) and Ge(4) each is coordinated to five oxygen atoms, one of them being a terminal –OH group. Ge(5) is located at the inversion center and adopts an octahedral coordination. The Ge–O distances within the trigonal bipyramidal and octahedral germanium centers are between 1.761(4) and 2.022(4) Å, which are markedly longer than those found in the GeO 4 tetrahedra. The connectivity of GeO 4 tetrahedra, GeO 5 trigonal bipyramids and GeO 6 octahedra gives rise to the 3D framework. In the structure, there are three types of channels. The smaller one has an eight-membered ring and runs along the [0 1 0] direction, as shown in Fig. 5 . The diameter of the channel is approximately 5.9 × 6.1 Å (corresponding to the interatomic O–O distances). Intersecting this channel are the two elliptical 10-membered windows, which have the same aperture and run along the [1 0 1] and [−1 0 1] directions, respectively. The diameter of the channels is approximately 7.1 × 7.6 Å ( Fig. 6 ). The quadruply protonated N , N ′-bis(3-aminopropyl)ethylene diamine molecules are located in the 10-ring channels and interact with the inorganic framework through hydrogen bonds as N(1)–H(4) ⋯ O(10) [ d = 2.27 Å], N(1)–H(5) ⋯ O(4) [ d = 2.39 Å], N(2)–H(6) ⋯ O(11) [ d = 2.20 Å], and N(2)–H(7) ⋯ O(7) [ d = 2.12 Å]. The extensive interactions between the organic moieties and the inorganic framework may play an important role to stabilize the structure, because attempts to remove of the organic moieties by calcination make the structure collapse. 4 Discussion Two new 3D open-framework germanates, [Cd 2 (C 2 N 2 H 8 ) 3 ][Ge 9 O 18 (OH) 4 ] ( 1 ) and (C 8 N 4 H 26 )[Ge 9 O 18 (OH) 4 ] ( 2 ), have been obtained as good-quality single crystals under similar hydrothermal conditions. The two compounds possess similar germanate framework that is assembled from Ge 9 O 18 (OH) 4 clusters. Interestingly, the molecular Ge 9 cluster has been successfully isolated under hydrothermal conditions by Tripathi et al. [28] . According to the aufbau principle of building higher-dimensional structures from that of the lower-dimensional ones [29] , it is conceivable that the use of this Ge 9 clusters as the precursor to produce novel open frameworks may be realized either in the solid state or via a solution mediated process. The role of the metal complex in the structure of 1 is subtle and merits some attention. In previous literatures, metal complexes are usually used as structure-directing agents to direct the formation of specific inorganic frameworks [30–38] . These complexes are accommodated in the free voids of the structures and interact with the macroanionic “host” frameworks through H-bonding interactions. In the present compound 1 the Cd atom is bound to the host via covalent bonds. The framework density defined as the number of polyhedra per 1000 Å 3 is 16.1 for 1 , compared with the value of 16.7 for the structurally related zinc germanates ZnGe-1A(B) [39] , and 16.4 for the cobalt germanate [Co 2 (C 2 N 2 H 8 ) 3 ][Ge 9 O 18 (OH) 4 ] [40] . Compound 2 possesses a similar germanate framework constructed from Ge 9 O 18 (OH) 4 clusters, however, the framework density of 13.2 for 2 makes it more of an open framework structure than 1 . Another way to quantify the openness of these types of compounds is to calculate the fraction of the unit cell volume not occupied by the framework atoms, assuming typical van der Waals’ radii for these species. A void space analysis with PLATON indicates that the inorganic framework of 2 occupies 58.0% of the unit cell volume, leaving 42.0% (1142.2 Å 3 out of the unit cell volume of 2722.5 Å 3 ) as “solvent accessible” space [41] . However, only 427.9 Å 3 (15.6% of the unit cell volume) for compound 1 remains unoccupied, when the C, N, and H atoms of the ethylenediamine molecules are ignored. The decreased free space of compound 1 is due to that the cadmium complexes block the 10-ring channels along the [1 0 1] and [−1 0 1] directions. 5 Conclusion Two new open-framework germanates, [Cd 2 (C 2 N 2 H 8 ) 3 ][Ge 9 O 18 (OH) 4 ] ( 1 ) and (C 8 N 4 H 26 )[Ge 9 O 18 (OH) 4 ] ( 2 ), were obtained as good quality single crystals under hydrothermal conditions. The structural analyses demonstrate that they have 3D structures assembled from the building unit of [Ge 9 O 18 (OH) 4 ] clusters. For 1 , the connectivity between the [Ge 9 O 18 (OH) 4 ] clusters and the cadmium complexes results in a neutral inorganic-organic hybrid framework; while the structures of 2 has a macroanionic inorganic framework with 8-, 10-, and 10-ring channels along the [0 1 0], [1 0 1] and [−1 0 1] directions. Acknowledgements This work was supported by the NSF of China (Grant nos. 20271050 and 20171045), the SRF for ROCS of State Education Ministry, the Ministry of Finance of China and the Talents Program of Chinese Academy of Sciences, and State Key Laboratory of Inorganic Synthesis and Preparative Chemistry of Jilin University. Supplementary material Supplementary data associated with this article can be found, in the online version, at doi:10.1016/j.micromeso.2004.06.020 . Supplementary material Figures Supplementary figures. References [1] M.E. Davis Nature 417 2002 813 [2] J. Cheng R. Xu J. Chem. Soc., Chem. Commun. 1991 483 [3] J. Cheng R. Xu G. Yang J. Chem. Soc., Dalton Trans. 1991 1537 [4] R.H. Jones J. Chen J.M. Thomas A. George M.B. Hursthouse R. Xu S. Li Y. Lu G. Yang Chem. Mater. 4 1992 808 [5] H. Li O.M. Yaghi J. Am. Chem. Soc. 120 1998 10569 [6] C. Cascales E. Gutiérrez-Puebla M. Iglesias M.A. Monge C. Ruı́z-Valero Angew. Chem. Int. Ed. 38 1999 2436 [7] X. Bu P. Feng G.D. 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Wilkinson Chem. Mater. 9 1997 2168 [33] K.R. Morgan G.J. Gainsford N.B. Milestone Chem. Commun. 1997 61 [34] M.J. Gray J.D. Jasper A.P. Wilkinson J.C. Hanson Chem. Mater. 9 1997 976 [35] D.J. Williams J.S. Kruger A.F. McLeroy A.P. Wilkinson J.C. Hanson Chem. Mater. 11 1999 2241 [36] J. Yu Y. Wang Z. Shi R. Xu Chem. Mater. 13 2001 2972 [37] G.-Y. Yang S.C. Sevov Inorg. Chem. 40 2001 2214 [38] Y. Wang J. Yu M. Guo R. Xu Angew. Chem. Int. Ed. 42 2003 4089 [39] X. Bu P. Feng G.D. Stucky Chem. Mater. 12 2000 1811 [40] N.N. Julius A. Choudhury C.N.R. Rao J. Solid State Chem. 170 2003 124 [41] A.L. Spek Acta Crystallogr. A 46 1990 C34",
        "keywords": [
            "Cluster",
            "Crystal structure",
            "Germanate",
            "Hydrothermal synthesis",
            "Open framework"
        ],
        "authors": [
            {
                "name": "Zhi-En Lin",
                "org": "Coordination and Hydrothermal Chemistry Group, State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, 155 West Yangqiao Road, Fuzhou, Fujian 350002, China"
            },
            {
                "name": "Jie Zhang",
                "org": "Coordination and Hydrothermal Chemistry Group, State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, 155 West Yangqiao Road, Fuzhou, Fujian 350002, China"
            },
            {
                "name": "Shou-Tian Zheng",
                "org": "Coordination and Hydrothermal Chemistry Group, State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, 155 West Yangqiao Road, Fuzhou, Fujian 350002, China"
            },
            {
                "name": "Guo-Yu Yang",
                "org": ""
            }
        ],
        "venue": "Microporous and Mesoporous Materials",
        "year": 2004
    },
    "FZD6sP2J": {
        "id": "FZD6sP2J",
        "title": "1D Polyoxometalate-based Inorganic-Organic Hybrid Derived from �-Octamolybdate ? Synthesis and Crystal Structure of [CoII(2, 2?-bipy)2]2[Mo8O26]",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Chun-Mei Wang",
                "org": ""
            },
            {
                "name": "Qing-Xin Zeng",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Guo-Yu Yang",
                "org": ""
            }
        ],
        "venue": "Zeitschrift Fur Anorganische Und Allgemeine Chemie",
        "year": 2005
    },
    "C1wFVL5W": {
        "id": "C1wFVL5W",
        "title": "Vibration-induced change of crystal structure in isotactic polypropylene and its improved mechanical properties",
        "abstract": "",
        "keywords": [
            "crystal structure",
            "injection",
            "ipp",
            "melt vibration"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Kaizhi Shen",
                "org": ""
            },
            {
                "name": "Shun Na",
                "org": ""
            },
            {
                "name": "Qiang Fu",
                "org": ""
            }
        ],
        "venue": "Journal of Polymer Science Part B-polymer Physics",
        "year": 2004
    },
    "TRLETjfE": {
        "id": "TRLETjfE",
        "title": "Vibration-Induced Self-Reinforcement of Injection Molding Samples of High-Density Polyethylene",
        "abstract": "",
        "keywords": [
            "high-density polyethylene",
            "mechanical property",
            "self-reinforcement",
            "vibration",
            "high density polyethylene",
            "crystal structure",
            "tensile strength"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Kaizhi Shen",
                "org": ""
            },
            {
                "name": "Yaofeng Wen",
                "org": ""
            },
            {
                "name": "Qiang Fu",
                "org": ""
            }
        ],
        "venue": "Polymer-plastics Technology and Engineering",
        "year": 2006
    },
    "WDxX9eNQ": {
        "id": "WDxX9eNQ",
        "title": "Crystal form and orientation of isotactic polypropylene samples prepared by vibration-injection molding",
        "abstract": "",
        "keywords": [
            "crystal form",
            "isotactic polypropylene",
            "orientation",
            "pole figure",
            "vibration-injection",
            "waxd",
            "sample preparation"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Tai Zeng",
                "org": ""
            },
            {
                "name": "Ji Zhu",
                "org": ""
            },
            {
                "name": "Yanwei Lei",
                "org": ""
            },
            {
                "name": "Kaizhi Shen",
                "org": ""
            },
            {
                "name": "Qiang Fu",
                "org": ""
            }
        ],
        "venue": "Journal of Applied Polymer Science",
        "year": 2007
    },
    "jdMom6Um": {
        "id": "jdMom6Um",
        "title": "Mechanical Property, Thermal Property and Crystal Structure of Isotactic Polypropylene Samples Prepared by Vibration Injection Molding",
        "abstract": "Summary  A self-designed pressure vibration injection device was used to study the effect of vibration frequency and vibration pressure\n on tensile strength and impact strength of iPP F401 vibration injection molding samples. Furthermore, vicat softening temperature,\n WAXD measurements and polarized microscopic observation were conducted. According to the results, tensile strength and impact\n strength increase with increasing vibration frequency and vibration pressure. The maximum increment of tensile strength is\n 26.1%. Under certain process conditions, there is a transition of the impact strength, whose maximum increment is 85%. The\n vicat softening temperatures have a significant increase of 6∼8 �C for the samples obtained at high vibration frequencies\n compared with that of static samples. According to pole figures, α-PP of vibration samples orientates much stronger than that\n of static samples. PM micrograghs show that vibration changes the crystal structure of samples and enhances their orientation.\n \n ",
        "keywords": [
            "vibration injection molding",
            "iPP",
            "thermal property",
            "mechanical property",
            "crystal structure"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Sichuan University College of Polymer Science & Engineering, State Key Laboratory of Polymer Materials Engineering 610065 Chengdu PR China"
            },
            {
                "name": "Ji Zhu",
                "org": "Sichuan University College of Polymer Science & Engineering, State Key Laboratory of Polymer Materials Engineering 610065 Chengdu PR China"
            },
            {
                "name": "Yanwei Lei",
                "org": "Sichuan University College of Polymer Science & Engineering, State Key Laboratory of Polymer Materials Engineering 610065 Chengdu PR China"
            },
            {
                "name": "Tai Zeng",
                "org": "Sichuan University College of Polymer Science & Engineering, State Key Laboratory of Polymer Materials Engineering 610065 Chengdu PR China"
            },
            {
                "name": "Kaizhi Shen",
                "org": "Sichuan University College of Polymer Science & Engineering, State Key Laboratory of Polymer Materials Engineering 610065 Chengdu PR China"
            },
            {
                "name": "Qiang Fu",
                "org": "Sichuan University College of Polymer Science & Engineering, State Key Laboratory of Polymer Materials Engineering 610065 Chengdu PR China"
            }
        ],
        "venue": "Polymer Bulletin",
        "year": 2008
    },
    "tFLV2Aot": {
        "id": "tFLV2Aot",
        "title": "Mechanical Property and Crystal Structure of Nylon6 Samples Prepared by Vibration Injection Molding",
        "abstract": "",
        "keywords": [
            "crystal structure",
            "mechanical property",
            "nylon6",
            "vibration injection molding"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "sichuan university"
            },
            {
                "name": "Yanwei Lei",
                "org": "sichuan university"
            },
            {
                "name": "Liangbo Yang",
                "org": "sichuan university"
            },
            {
                "name": "Qixiong Zhou",
                "org": "sichuan university"
            },
            {
                "name": "Yaofeng Wen",
                "org": "sichuan university"
            },
            {
                "name": "Kaizhi Shen",
                "org": "sichuan university"
            },
            {
                "name": "Qiang Fu",
                "org": "sichuan university"
            }
        ],
        "venue": "Polymer-plastics Technology and Engineering",
        "year": 2009
    },
    "UzZbdBj7": {
        "id": "UzZbdBj7",
        "title": "Effect of melt vibration on structure and mechanical properties of HDPE/nano-CaCO3 blend",
        "abstract": "Melt vibration technology was used to prepare injection sample of HDPE/nano-CaCO3 blend, whose mechanical properties were improved significantly. Compared with conventional injection molding, the enhancements of the tensile strength and impact strength of the sample molded by vibration injection molding were 41.2 and 43.2%, respectively. According to the SEM, WAXD, and DSC measurement, it was found that a much better dispersion of nano-CaCO3 in sample was achieved by vibration injection molding. Moreover, crystal orientation degree of matrix HDPE increased under the effect of melt vibration. The crystallinity degree of HDPE in vibration sample increased by 5.5% compared with conventional one. The improvement of mechanical properties of HDPE/nano-CaCO3 blend prepared by low-frequency vibration injection molding attributes to the even distribution of nano-CaCO3 particles and the orientation of HDPE crystals and increase of crystallinity degree under the influence of melt vibration. © 2010 Springer-Verlag.",
        "keywords": [
            "Melt vibration",
            "HDPE/nano-CaCO",
            "3",
            "blend",
            "Mechanical properties",
            "Structure"
        ],
        "authors": [
            {
                "name": "XueQin Gao",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Cong Deng",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Jing Xu",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Zhongming Li",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Kaizhi Shen",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            }
        ],
        "venue": "Polymer Bulletin",
        "year": 2010
    },
    "cBJQb95y": {
        "id": "cBJQb95y",
        "title": "Effect of melt vibration on structure and mechanical properties of HDPE/nano-CaCO<sub>3</sub> blend",
        "abstract": "Melt vibration technology was used to prepare injection sample of HDPE/nano-CaCO3 blend, whose mechanical properties were improved significantly. Compared with conventional injection molding, the enhancements\n of the tensile strength and impact strength of the sample molded by vibration injection molding were 41.2 and 43.2%, respectively.\n According to the SEM, WAXD, and DSC measurement, it was found that a much better dispersion of nano-CaCO3 in sample was achieved by vibration injection molding. Moreover, crystal orientation degree of matrix HDPE increased under\n the effect of melt vibration. The crystallinity degree of HDPE in vibration sample increased by 5.5% compared with conventional\n one. The improvement of mechanical properties of HDPE/nano-CaCO3 blend prepared by low-frequency vibration injection molding attributes to the even distribution of nano-CaCO3 particles and the orientation of HDPE crystals and increase of crystallinity degree under the influence of melt vibration.",
        "keywords": [
            "melt vibrationhdpe/nano-caco3 blendmechanical properties � structure"
        ],
        "authors": [
            {
                "name": "Xue-qin GaoCong",
                "org": "Sichuan University College of Polymer Science and Engineering, State Key Laboratory of Polymer Materials Engineering Chengdu 610065 China"
            },
            {
                "name": "Cong Deng",
                "org": "Sichuan University College of Polymer Science and Engineering, State Key Laboratory of Polymer Materials Engineering Chengdu 610065 China"
            },
            {
                "name": "Jing Xu",
                "org": "Sichuan University College of Polymer Science and Engineering, State Key Laboratory of Polymer Materials Engineering Chengdu 610065 China"
            },
            {
                "name": "Zhong-ming Li",
                "org": "Sichuan University College of Polymer Science and Engineering, State Key Laboratory of Polymer Materials Engineering Chengdu 610065 China"
            },
            {
                "name": "Jie Zhang",
                "org": "Sichuan University College of Polymer Science and Engineering, State Key Laboratory of Polymer Materials Engineering Chengdu 610065 China"
            },
            {
                "name": "Kai-zhi Shen",
                "org": "Sichuan University College of Polymer Science and Engineering, State Key Laboratory of Polymer Materials Engineering Chengdu 610065 China"
            }
        ],
        "venue": "Polymer Bulletin",
        "year": 2010
    },
    "xIVg1T1J": {
        "id": "xIVg1T1J",
        "title": "Screen of Bacillus thuringiensis toxins for transgenic rice to control Sesamia inferens and Chilo suppressalis.",
        "abstract": "Transgenic rice to control stem borer damage is under development in China. To assess the potential of Bacillus thuringiensis (Bt) transgenes in stem borer control, the toxicity of five Bt protoxins (Cry1Aa, Cry1Ab, Cry1Ac, Cry1Ba and Cry1Ca) against two rice stem borers, Sesamia inferens (pink stem borer) and Chilo suppressalis (striped stem borer), was evaluated in the laboratory by feeding neonate larvae on artificial diets containing Bt protoxins. The results indicated that Cry1Ca exhibited the highest level of toxicity to both stem borers, with an LC(50) of 0.24 and 0.30 microg/g for C. suppressalis and S. inferens, respectively. However, S. inferens was 4-fold lower in susceptibility to Cry1Aa, and 6- and 47-fold less susceptible to Cry1Ab and Cry1Ba, respectively, compared to C. suppressalis. To evaluate interactions among Bt protoxins in stem borer larvae, toxicity assays were performed with mixtures of Cry1Aa/Cry1Ab, Cry1Aa/Cry1Ca, Cry1Ac/Cry1Ca, Cry1Ac/Cry1Ba, Cry1Ab/Cry1Ac, Cry1Ab/Cry1Ba, and Cry1Ab/Cry1Ca at 1:1 (w/w) ratios. All protoxin mixtures demonstrated significant synergistic toxicity activity against C. suppressalis, with values of 1.6- to 11-fold higher toxicity than the theoretical additive effect. Surprisingly, all but one of the Bt protoxin mixtures were antagonistic in toxicity to S. inferens. In mortality-time response experiments, S. inferens demonstrated increased tolerance to Cry1Ab and Cry1Ac compared to C. suppressalis when treated with low or high protoxin concentrations. The data indicate the utility of Cry1Ca protoxin and a Cry1Ac/Cry1Ca mixture to control both stem borer populations.",
        "keywords": [
            "susceptibility",
            "sesamia inferens",
            "bacillus thuringiensis",
            "synergism",
            "chilo suppressalis",
            "transgenic rice"
        ],
        "authors": [
            {
                "name": "Yulin Gao",
                "org": ""
            },
            {
                "name": "Yang Hu",
                "org": ""
            },
            {
                "name": "Qiang Fu",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": "State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100193, PR China"
            },
            {
                "name": "Brenda Oppert",
                "org": "USDA ARS Center for Grain and Animal Health Research, 1515 College Avenue, Manhattan, KS 66502, USA"
            },
            {
                "name": "Fengxiang Lai",
                "org": "State Key Laboratory of Rice Biology, China National Rice Research Institute, Hangzhou 310006, PR China"
            },
            {
                "name": "Yufa Peng",
                "org": "State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100193, PR China"
            },
            {
                "name": "Zhitao Zhang",
                "org": "State Key Laboratory of Rice Biology, China National Rice Research Institute, Hangzhou 310006, PR China"
            }
        ],
        "venue": "Journal of invertebrate pathology",
        "year": 2010
    },
    "H0bfJGsP": {
        "id": "H0bfJGsP",
        "title": "Study on the morphology and properties of PP/HDPE blend prepared by vibration injection molding",
        "abstract": "A self-designed pressure vibration injection molding device was used to study the effect of vibration frequency and vibration pressure on tensile strength and impact strength of PP/HDPE (70/30) samples prepared by vibration injection molding. Furthermore, DSC and scanning electron microscopy (SEM) observations were conducted. The tensile strength and impact strength increase with increasing vibration frequency and vibration pressure. SEM micrographs show that the orientation degree of the vibration sample obtained at 190C obviously increases compared with the static sample, and the clusters of lamellae are stretched along the flow direction, whereas their lateral sizes decrease correspondingly. There is no evident orientation in the core layer of the vibration sample obtained at 230C. DSC testing results show that the degree of crystallinity of vibration samples are higher than those of static samples. Copyright © Taylor & Francis Group, LLC.",
        "keywords": [
            "crystal structure",
            "mechanical properties",
            "PP/HDPE blends",
            "vibration injection molding"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Xinyuan Qian",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Fanghui Liu",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Ji Zhu",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Kaizhi Shen",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "XueQin Gao",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            }
        ],
        "venue": "Journal of Macromolecular Science, Part B: Physics",
        "year": 2011
    },
    "smScsQqI": {
        "id": "smScsQqI",
        "title": "Shish–kebab-like cylindrulite structures resulted from periodical shear-induced crystallization of isotactic polypropylene",
        "abstract": "In this study, isotactic polypropylene (iPP) samples were prepared by conventional injection molding (CIM) and pressure vibration injection molding (PVIM), in which a periodical shear field was imposed on the iPP melt during the cooling solidification. The distribution of supermolecular structures of samples was investigated by Polarized Light Microscopy (PLM) and Scanning Electron Microscopy (SEM). Results show that the through-the thickness-morphology of sample prepared by CIM features a typical skin-core structure, as a result of general shear-induced crystallization. This structure can be divided into three layers, including a skin layer in which the shish-kebab structure was found, a transition region with deformed spherulite structure and a core layer with spherulitic structure. However, the morphology of the sample prepared by PVIM, as a result of periodical shear-induced crystallization, features a richer and fascinating supermolecular structure and can not be roughly divided into three layers. A region full of shish-kebab-like cylindrulite structures was found between the transition region and the core layer, which is rare to be seen in conventional injection molding. Based on their various core structures, two kinds of shish-kebab-like cylindrulites were defined: one is multi-fibril-core cylindrulite of which core is an assembly of multiple fibrils, and the other is single-fibril-core cylindrulite of which the core just contains a single fibril. Based on the investigated results, a schematic illustration is proposed to depict the through-the thickness-distribution of supermolecular structure of iPP sample prepared by PVIM. The mechanism of the formation of the two kinds of shish-kebab-like cylindrulite structures is also depicted by a schematic illustration, and it was discussed in terms of periodical shear-induced crystallization. © 2011 Elsevier Ltd. All rights reserved.",
        "keywords": [
            "cylindrulite",
            "periodical shear-induced crystallization",
            "isotactic polypropylene",
            "sample preparation",
            "polarized light microscopy",
            "scanning electron microscopy"
        ],
        "authors": [
            {
                "name": "Qixiong Zhou",
                "org": "State Key Laboratory of Polymer Materials Engineering, College of Polymer Science and Engineering, Sichuan University, Chengdu, China"
            },
            {
                "name": "Fanghui Liu",
                "org": "State Key Laboratory of Polymer Materials Engineering, College of Polymer Science and Engineering, Sichuan University, Chengdu, China"
            },
            {
                "name": "Chao Guo",
                "org": "State Key Laboratory of Polymer Materials Engineering, College of Polymer Science and Engineering, Sichuan University, Chengdu, China"
            },
            {
                "name": "Qiang Fu",
                "org": "State Key Laboratory of Polymer Materials Engineering, College of Polymer Science and Engineering, Sichuan University, Chengdu, China"
            },
            {
                "name": "Kaizhi Shen",
                "org": "State Key Laboratory of Polymer Materials Engineering, College of Polymer Science and Engineering, Sichuan University, Chengdu, China"
            },
            {
                "name": "Jie Zhang",
                "org": ""
            }
        ],
        "venue": "Polymer",
        "year": 2011
    },
    "mhnPjFiz": {
        "id": "mhnPjFiz",
        "title": "Electrical properties of isotactic polypropylene/multiwalled carbon nanotubes composites prepared by vibration injection molding",
        "abstract": "To study the effect of vibration field on the electrical conductivity properties of nanocomposites, isotactic polypropylene (iPP)/multiwalled carbon nanotubes (MWCNT) composites were prepared by conventional injection molding and vibration injection molding. Results showed that the electrical conductivity of iPP/MWCNT composites was significantly promoted by vibration injection molding. Vibration injection molded samples had a percolation threshold of about 2.7 wt% compared with the threshold of about 4.5 wt% for conventional injection molded samples. The effects of test locations and vibration frequency on the electrical conductivity of composites were investigated. The samples exhibited an inhomogeneity along the injection direction. The electrical conductivity of the samples was different at different test locations and increased with increasing vibration frequency. Polarized light microscopy (PLM) results indicated that vibration injection molding can induce MWCNT aggregates to be stretched and oriented along the flow direction, which could form conductive networks and greatly enhance the electrical conductivity of iPP/MWCNT composites. © 2011 Copyright Taylor and Francis Group, LLC.",
        "keywords": [
            "electrical property",
            "isotactic polypropylene",
            "multiwalled carbon nanotubes",
            "nanocomposite",
            "vibration frequency",
            "vibration injection molding"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Xian Wu",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Chao Guo",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Liangbo Yang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "XueQin Gao",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Hesheng Xia",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            }
        ],
        "venue": "Journal of Macromolecular Science, Part B: Physics",
        "year": 2011
    },
    "XSHWTKZU": {
        "id": "XSHWTKZU",
        "title": "Morphological distribution in micro-injected polypropylene parts in the presence of β-nucleating agent",
        "abstract": "Micro-injection molding is attracting much attention nowadays. Characterization of the morphological distribution in parts prepared by micro-injection molding is thus of growing importance. The morphological features of micro-parts may strongly differ from those of the macro-parts prepared by conventional injection molding, resulting in specific physical properties. In the present study, β-nucleated isotactic polypropylene micro-parts (PPB) with 200μm thickness, as well as macro-parts (PPB) with 2000m thickness, were prepared. Polarized light microscopy (PLM), scanning electron microscopy (SEM), differential scanning calorimetry (DSC), and wide-angle X-ray diffraction (WAXD) were used to investigate their morphological features. The results show that the morphology distribution in μPPB had many differences from that of the PPB. The one-dimensional WAXD and DSC analysis showed similar results; the degree of crystallinity of the μPPB was higher than that of the PPB. However, the content of β-crystals of PPB was lower than that of the PPB. This can be explained by the restraining effect for the formation of β-crystals in β-nucleated isotactic polypropylene (iPP) under the strong shear field. The through-the thickness-morphology of both PPB and PPB exhibited a \"skin-core\" structure from PLM observations, but the former had a large fraction of shear layer in comparison to the latter implied. The SEM observations showed that the shear layer of PPB consisted of a highly oriented shish-kebab structure, while that of the core layer consisted of deformed spherulites structure. The two-dimensional WAXD pattern of the core layer of μPPB, showing full Debye rings, indicated an overall random orientation of the iPP chains, while the arcing indicated a pronounced orientation in the shear layer. The more pronounced arcing of the PPB indicated a more pronounced orientation. Copyright © 2012 Taylor and Francis Group, LLC.",
        "keywords": [
            "β-nucleating agent",
            "micro-injection molding",
            "morphological distribution",
            "orientation",
            "polypropylene",
            "shish-kebab",
            "skin-core structure"
        ],
        "authors": [
            {
                "name": "Hong Liu",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Lei Zhang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Fanghui Liu",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Chao Guo",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            }
        ],
        "venue": "Journal of Macromolecular Science, Part B: Physics",
        "year": 2012
    },
    "dlCT9wHl": {
        "id": "dlCT9wHl",
        "title": "Study of Micro-Injection Moulding: Factors Affecting the Content of the β-phase in Isotactic Polypropylene with β-nucleating Agent",
        "abstract": "The special processing conditions of micro-injection moulding will affect the micro-structure of polymer microparts processed by micro-injection moulding. In this article, two-dimensional wide-angle X-ray diffraction (2D-WAXD) and differential scanning calorimetry (DSC) were used to study the influence of nucleating agent concentration, mould temperature and injection pressure on content of the β-phase in isotactic polypropylene (iPP) with β-nucleating agent in micro-injection moulding. It was found that the high shear stress during micro-injection moulding could induce the formation of β-phase crystals in pure iPP, but which could restrain the formation of β-phase crystals in iPP with β-nucleating agent. The β-crystal content in micro-injection moulded samples decreased continuously with increasing the mould temperature from 130°C to 160°C. Besides, the shear stress that could restrain the nucleating efficiency of β-nucleating agent in β-nucleated iPP increased with the rise of the injection pressure and resulted in the decrease of β-phase crystals in the sample. © 2012 Copyright Taylor and Francis Group, LLC.",
        "keywords": [
            "β-nucleating agent",
            "β-phase content",
            "isotactic polypropylene",
            "micro-injection moulding",
            "processing factors",
            "differential scanning calorimetry",
            "shear stress"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Lei Zhang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Hong Liu",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Fanghui Liu",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Chao Guo",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            }
        ],
        "venue": "Polymer - Plastics Technology and Engineering",
        "year": 2012
    },
    "gUV1FNiC": {
        "id": "gUV1FNiC",
        "title": "Morphological evolution of HDPE parts in the microinjection molding: Comparison with conventional injection molding",
        "abstract": "To compare the difference of morphological evolution of HDPE micropart and macropart, micropart with 200 μm thickness and macropart with 2000 μm thickness were prepared. The PLM images of micropart and macropart exhibited a similar \"skin-core\" structure, but the micropart showed a much larger fraction of orientation layer. The SEM observation of core layer of micropart featured an unoriented lamellae structure and shear layer of micropart showed a highly oriented shish-kebab structure. The 2D-WAXD patterns of shear layer of macropart indicated twisted oriented shish-kebab (KM-I) structures, however that of micropart indicated untwisted oriented shish-kebab (KM-II) structures which was firstly found in microinjection molding. The diffraction pattern of the micropart exhibited stronger azimuthal dependence than the shear layer of macropart, indicating the most pronounced orientation of HDPE chains within lamellae. Copyright © 2012 Wiley Periodicals, Inc.",
        "keywords": [
            "conventional injection",
            "hdpe",
            "microinjection molding",
            "morphology"
        ],
        "authors": [
            {
                "name": "Chao Guo",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Fanghui Liu",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Xian Wu",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Hong Liu",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            }
        ],
        "venue": "Journal of Applied Polymer Science",
        "year": 2012
    },
    "DNAbDMvi": {
        "id": "DNAbDMvi",
        "title": "The morphology and property of HDPE in the presence of oscillation pressure and poly(ethylene terephthalate)",
        "abstract": "The injection-molded specimens of neat HDPE and the PET/HDPE blends were prepared by conventional injection molding (CIM) and by pressure vibration injection molding (PVIM), respectively. The effect of oscillation pressure and PET phase with different shapes on superstructure and its crystal orientation distribution of injection molded samples were characterized by differential scanning calorimetry (DSC), scanning electron microscopy (SEM), and two-dimension wide-angle X-ray diffraction techniques (2D-WAXD). Hermans' orientation functions were determined from the wide-angle X-ray diffraction patterns. With the PET particles added, the shear viscosity of blend increase and crystallization rate of HDPE phase is enhanced. For the neat HDPE samples, with the promotion from oscillation shear, the orientation parameter experienced a large increase, moreover, the PVIM can induce transverse lamellae (kebabs) twisting in growth direction. Because of the redefined flow field and nucleation effect of PET particles, the crystal orientation of blend is also increased. So the tensile strength of vibration samples enhanced and elongation at break declined. © 2011 Wiley Periodicals, Inc.",
        "keywords": [
            "conventional injection molding",
            "crystal orientation",
            "lamellae twisting",
            "pet/hdpe blend",
            "pressure vibration injection molding"
        ],
        "authors": [
            {
                "name": "Xinyuan Qian",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Hong Liu",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Fanghui Liu",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "XueQin Gao",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            }
        ],
        "venue": "Journal of Applied Polymer Science",
        "year": 2012
    },
    "3lqcZNmo": {
        "id": "3lqcZNmo",
        "title": "Design of biological filter for iron and manganese removal from water.",
        "abstract": "The technology core of biological removal of iron and manganese by contact oxidation is iron and manganese oxidizing bacteria. This article made a study on down flow and up flow filtration, the results show that down flow filtration of the homogenous filter medium is more adapted to the reproduction of biotic formation. Homogeneous filter increase the depth of effective biological filter and the biomass that develop the bio-chemical capability of the biological filter. Homogeneous filter increase removal capability of Fe/Mn and alleviate the formation of sludge cake, which can get a quite backwash. Down flow homogeneous biological filter can solve some engineering problems of heterogeneous up flow filtration. The down flow homogeneous biological filter is more adapted to the removal of Fe/Mn in groundwater.",
        "keywords": [
            "groundwater",
            "remove",
            "biological oxidation",
            "filter structure",
            "manganese",
            "iron"
        ],
        "authors": [
            {
                "name": "Hong Yang",
                "org": ""
            },
            {
                "name": "Dong Li",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Ruixia Hao",
                "org": ""
            },
            {
                "name": "Bo Li",
                "org": ""
            }
        ],
        "venue": "Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering",
        "year": 2004
    },
    "Q1IG63YD": {
        "id": "Q1IG63YD",
        "title": "Operational performance of biological treatment plant for iron and manganese removal",
        "abstract": "The treatment plant was designed according to the theory of biological fixation and removal of manganese from water. The process included low level aeration followed by single stage filtration. The separated native iron and manganese oxidizing bacteria after multiplication were inoculated to the filtering medium alongside raw water. After 2-3 months of culturing, the filter exhibited strong manganese removal capability. Under the usual filtration rate conditions, the manganese concentration in the raw water was 0.575-3.05 mg l-1 and total iron (T-Fe) 0.01-0.5 mg l-1; the manganese concentration in the filtrate was 0.05 mg l-1 and T-Fe in trace, which was superior to the Chinese National Standard for drinking water (Fe<0.3 mg l-1, Mn<0.1 mg l-1). The product water was stable and of high quality that completely meets the above-mentioned standard. The process can reduce investment costs by 50 million yuans (¥) and operation and maintenance cost by ¥12,000 per day compared with traditional processes. © IWA Publishing 2005.",
        "keywords": [
            "biological fixation and removal of manganese",
            "cost-effective process",
            "low level aeration",
            "simultaneous removal"
        ],
        "authors": [
            {
                "name": "Dong Li",
                "org": "Tsinghua University(Tsinghua University,Tsinghua Univ,Tsinghua Univ.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Harbin Institute of Technology(Harbin Institute of Technology,Harbin Inst. of Technol.),Harbin,China"
            },
            {
                "name": "Hongtao Wang",
                "org": "Tsinghua University(Tsinghua University,Tsinghua Univ,Tsinghua Univ.),Beijing,China"
            },
            {
                "name": "Hong Yang",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "Baozhen Wang",
                "org": "Harbin Institute of Technology(Harbin Institute of Technology,Harbin Inst. of Technol.),Harbin,China"
            }
        ],
        "venue": "Journal of Water Supply: Research and Technology - AQUA",
        "year": 2005
    },
    "8qIMRg9S": {
        "id": "8qIMRg9S",
        "title": "Innovative nitrogen removal process for domestic wastewater treatment",
        "abstract": "The performances of anaerobic ammonium oxidation (ANAMMOX) process in nitrogen removal from secondary effluent of domestic wastewater were investigated by using a downflow anoxic biofilter. The results showed that ANAMMOX process is suitable for advanced wastewater treatment as well as ammonia-rich wastewater treatment. The relation between ammonium consumption, nitrite consumption and nitrate production could be found to be m(ΔNH4 +-N): m(ΔNO2 --N): m(ΔNO3 --N)=1:(1-1.5): (0.17-0.27), and the consumption of total carbon ranged from 0.3 to 1.3 mg/L during the experiment. The results showed that ammonia removal rate were improved with increasing nitrite concentration, and the reactor rate reached a climax at 118.4 mg/L of nitrite nitrogen concentration. Beyond the concentration, the ANAMMOX process was significantly inhibited though the ANAMMOX bacteria still showed a relatively high activity. The data also indicated that the proper ratio of m(NO2 --N):m(NH4 +-N) in influent was 1.3:1 to achieve excellent nitrogen removal. Besides, the data suggested that the pH could be used as an indicator to monitor the course of ANAMMOX reaction in biofilter. The pH increased steadily with the ANAMMOX reaction, and stopped changing as the reaction finished.",
        "keywords": [
            "Advanced treatment",
            "ANAMMOX",
            "Anoxic biofilter",
            "Domestic wastewater",
            "Nitrite",
            "Nitrogen removal",
            "PH"
        ],
        "authors": [
            {
                "name": "Jie Li",
                "org": "Harbin Institute of Technology(Harbin Institute of Technology,Harbin Inst. of Technol.),Harbin,China"
            },
            {
                "name": "XIONG Bi-yong",
                "org": "Harbin Institute of Technology(Harbin Institute of Technology,Harbin Inst. of Technol.),Harbin,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Harbin Institute of Technology(Harbin Institute of Technology,Harbin Inst. of Technol.),Harbin,China"
            }
        ],
        "venue": "Harbin Gongye Daxue Xuebao/Journal of Harbin Institute of Technology",
        "year": 2007
    },
    "8g3VAuWV": {
        "id": "8g3VAuWV",
        "title": "Optimal rehabilitation model of water supply network with non-dominated genetic algorithm-II",
        "abstract": "To improve the objectivity of rehabilitation model for water supply network and provide more feasible solutions, a multi-objective rehabilitation model was developed by transforming the hydraulic constraints of the single objective model into objective functions, and the non-dominated sorting genetic algorithm-II (NS-GA-II) was used to solve the developed model. The test on a case of water supply network shows that a solution satisfied with all objectives can be obtained by considering the low pressure node, high load pipe and rehabilitation cost as objectives of rehabilitation model. The introduction of multi-objective concept and multi-objective oriented algorithm (NSGA-II) into the solving process of rehabilitation problem for water supply network overcomes the conflict between the rehabilitation model with one objective and that with multi-objectives, which avoids the uncertainties brought by using weight coefficients or punish functions. The introduction of artificial induction gene mutation operator accelerates the convergence speed of population, thus improves the convergence speed, which proves the feasibility of the method.",
        "keywords": [
            "Artificial inducement mutation",
            "Genetic algorithm",
            "Non-dominated sorting",
            "Optimal rehabilitation",
            "Water supply network"
        ],
        "authors": [
            {
                "name": "Xi Jin",
                "org": "Harbin Institute of Technology(Harbin Institute of Technology,Harbin Inst. of Technol.),Harbin,China"
            },
            {
                "name": "Jinliang Gao",
                "org": "Harbin Institute of Technology(Harbin Institute of Technology,Harbin Inst. of Technol.),Harbin,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Harbin Institute of Technology(Harbin Institute of Technology,Harbin Inst. of Technol.),Harbin,China"
            },
            {
                "name": "Fang Wang",
                "org": "Wuhan Academy of Urban Planning and Design(Wuhan Academy of Urban Planning and Design,Wuhan Academy of Urban Planning Design),Wuhan,China"
            }
        ],
        "venue": "Harbin Gongye Daxue Xuebao/Journal of Harbin Institute of Technology",
        "year": 2008
    },
    "Q5D3E5KJ": {
        "id": "Q5D3E5KJ",
        "title": "Spontaneous self-assembly of metal-organic cationic nanocages to form monodisperse hollow vesicles in dilute solutions.",
        "abstract": "In this communication we report the unprecedented spontaneous self-assembly of cationic nanoporous metal-organic coordination cages (nanocages) into giant hollow vesicle-like structures in polar solvents. Such highly soluble nanocages (macrocations) have separated hydrophobic regions. However, their assembly is not due to hydrophobic interactions but the counterion-mediated attractions, very similar to the unique self-assembly of polyoxometalate macroanions into single-layer, spherical blackberry structures, as characterized by laser light scattering and TEM studies. This is the first study on the solution behavior of metal-organic nanocages and also the first report on the self-assembly of soluble macrocations. Therefore, the blackberry structure is likely to be a universal type of self-assembly for soluble macroions. In addition, the self-assembled nanocages can provide blackberry structures a wide range of organic functionalities that are impossible to reach with purely inorganic systems, which may open the door to many types of applications.",
        "keywords": [
            "self assembly"
        ],
        "authors": [
            {
                "name": "Dong Li",
                "org": "Department of Chemistry, Lehigh University, Bethlehem, Pennsylvania 18015, USA."
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Kai Landskron",
                "org": ""
            },
            {
                "name": "Tianbo Liu",
                "org": ""
            }
        ],
        "venue": "Journal of the American Chemical Society",
        "year": 2008
    },
    "AsqgGnOA": {
        "id": "AsqgGnOA",
        "title": "Research on the removal of alachlor by homogeneous photocatalytic oxidation process",
        "abstract": "In the study, UV/H2O2 photodegradation system was adopted in the removal of alachlor in water, and the effect of pH, influent temperature, dose of H2O2, influent concentration of alachlor and other conditions on the photodegradation efficiency were discussed. The results indicated that under different experimental conditions, alachlor got high removal efficiency by UV/H2O2 photodegradation systems, and the removal of alachlor could reach 99% more by the time of 10min.The concentration of ·OH from photodecompose of H2O2 were key factors that affected reaction rate, and the conditions of 20°C, pH=7.0, and 70mg/L of H2O2 were optimum photodegradation conditions of alachlor.",
        "keywords": [
            "Insecticides",
            "Optimum reaction conditions",
            "Photodegradation",
            "Removal efficiency"
        ],
        "authors": [
            {
                "name": "KONG Xiang-ji",
                "org": "Harbin Institute of Technology(Harbin Institute of Technology,Harbin Inst. of Technol.),Harbin,China"
            },
            {
                "name": "Dong Li",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Harbin Institute of Technology(Harbin Institute of Technology,Harbin Inst. of Technol.),Harbin,China"
            }
        ],
        "venue": "Beijing Gongye Daxue Xuebao / Journal of Beijing University of Technology",
        "year": 2009
    },
    "uUfM6nu6": {
        "id": "uUfM6nu6",
        "title": "A preliminary study on total removal efficiency of organic pollutants in sewage by Harbin municipal sewage treatment plant",
        "abstract": "To evaluate the removal efficiency of organic pollutants in the sewage by Harbin municipal sewage treatment plant, the influent and effluent samples from the plant were pretreated by liquid-liquid extraction (LLE) under conditions of acidity, neutrality and alkalescence in sequence, and then were analyzed by gas chromatograph-mass spectrum (GC-MS) procedures. Results indicate that there are 70 species of organic pollutants in the influent sample of the plant, which mainly consist of alkyls, benzene series, esters, and heterocyclic compounds. Some of these organic pollutants are biotoxic and belong to persistent organic pollutants (POPs). Four species among them are on the list of Prior Pollutants of Environmental Protection Agency of USA (USEPA). However, 7 species of organic pollutants appearing in the effluent sample mainly include alkyls of multi-carbons and phthalate esters. The removal efficiency of phthalates is poor because of their poor biodegradability. The sewage treatment technique is effective in removing most of organics pollutants.",
        "keywords": [
            "GC-MS",
            "Municipal sewage",
            "Organic pollutants",
            "Removal efficiency"
        ],
        "authors": [
            {
                "name": "KONG Xiang-ji",
                "org": "Harbin Institute of Technology(Harbin Institute of Technology,Harbin Inst. of Technol.),Harbin,China"
            },
            {
                "name": "LI Xiang-kun",
                "org": "Harbin Institute of Technology(Harbin Institute of Technology,Harbin Inst. of Technol.),Harbin,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Harbin Institute of Technology(Harbin Institute of Technology,Harbin Inst. of Technol.),Harbin,China"
            },
            {
                "name": "Dong Li",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "ZHANG Xue-mei",
                "org": "Academy of Measurement(Academy of Measurement),Harbin,China"
            },
            {
                "name": "Yan Zhao",
                "org": "Harbin Institute of Technology(Harbin Institute of Technology,Harbin Inst. of Technol.),Harbin,China"
            },
            {
                "name": "Yang Lv",
                "org": "Harbin Institute of Technology(Harbin Institute of Technology,Harbin Inst. of Technol.),Harbin,China"
            }
        ],
        "venue": "Journal of Harbin Institute of Technology (New Series)",
        "year": 2009
    },
    "5kC8mQ7I": {
        "id": "5kC8mQ7I",
        "title": "Determinations of PCBs in municipal sewage with SPE-GC-MS",
        "abstract": "The optimum pretreatment process is especially required in order to get the exact concentration of PCBs in municipal sewage. In the paper, C18 solid-phase extraction (SPE) columns were adopted in the enriching of PCBs in Harbin municipal sewage, and the target compounds were extracted with mixed extractant of acetone and n-hexane of 1:1 in the optimum dosage of 10 milliliter. And the extract was further purified with sulfuric acid, silica gel and anhydrous sodium sulfate. GC-MS was applied in the identification and quantification of PCBs in sewage samples, and seven PCBs congeners recommended by EPA were chosen as the exterior references. It indicated that the total concentration of the seven PCBs in the sewage samples was 27.75 ng/L, the relative standard deviations of the method were in the scope of 1.6%-8.8%, the recoveries were between 84% and 103%, and the lowest detection limit of PCBs was 0.014 μg/L.",
        "keywords": [
            "Extractant",
            "GC-MS",
            "Municipal sewage",
            "PCBs",
            "SPE"
        ],
        "authors": [
            {
                "name": "Xiangji Kong",
                "org": "Harbin Institute of Technology(Harbin Institute of Technology,Harbin Inst. of Technol.),Harbin,China"
            },
            {
                "name": "Dong Li",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Harbin Institute of Technology(Harbin Institute of Technology,Harbin Inst. of Technol.),Harbin,China"
            },
            {
                "name": "Xuemei Zhang",
                "org": "Academy of Measurement(Academy of Measurement),Harbin,China"
            },
            {
                "name": "KeBin Li",
                "org": "Beijing Tian Heng Real Estate Corporation Limited(Beijing Tian Heng Real Estate Corporation Limited),Beijing,China"
            }
        ],
        "venue": "Beijing Gongye Daxue Xuebao / Journal of Beijing University of Technology",
        "year": 2009
    },
    "g2yTxfej": {
        "id": "g2yTxfej",
        "title": "An environmental perspective of nitrogen cycle",
        "abstract": "",
        "keywords": [
            "anammox",
            "cycle",
            "denitrification",
            "economic",
            "environment",
            "global",
            "impact",
            "nitrification",
            "nitrogen",
            "social",
            "economic impact",
            "environmental impact",
            "conversion",
            "water treatment",
            "wastewater treatment",
            "ecosystems",
            "oxidation",
            "nitrogen cycle",
            "wastewater",
            "waste treatment",
            "cycling",
            "nutrient cycle",
            "terrestrial ecosystems"
        ],
        "authors": [
            {
                "name": "Zhiyong Tian",
                "org": ""
            },
            {
                "name": "Dong Li",
                "org": ""
            },
            {
                "name": "Junliang Liu",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Christal Banks",
                "org": ""
            },
            {
                "name": "Gang Chen",
                "org": ""
            }
        ],
        "venue": "International Journal of Global Environmental Issues",
        "year": 2009
    },
    "DyLZJXW3": {
        "id": "DyLZJXW3",
        "title": "Effect factors for ANAMMOX biofilter at room temperature",
        "abstract": "In order to promote the engineering applications of anaerobic ammonium oxidation(ANAMMOX) for urban sewage treatment, the impact of nitrate, phosphate, ammonia and nitrite on the running performance of ANAMMOX biofilter reactor at room temperature was investigated respectively. Experimental results show that there is no significant impact on the TN removal load when the influent NO3 --N concentration is increased to about 500 mg/L. However, the TN removal load will drop obviously when the infulent TP concentration is higher than 10 mg/L, which can be restored after stopping dosing phosphate. Appropriately increasing the concentration of NH4 +-N and NO2 --N is beneficial to the improvement of TN removal load. At room temperature conditions, nitrate basically has no effect on the ANAMMOX biofilter for municipal wastewater with low ammonia. But for phosphate, it has a certain impact on the activity of ANAMMOX, and the improvement of the influent phosphate concentration has a reversible inhibition for ANAMMOX reaction in the urban sewage with low ammonia.",
        "keywords": [
            "ANAMMOX",
            "Biofilter",
            "Biological nitrogen removal",
            "Municipal wastewater",
            "Room temperature"
        ],
        "authors": [
            {
                "name": "Dong Li",
                "org": "Harbin Institute of Technology(Harbin Institute of Technology,Harbin Inst. of Technol.),Harbin,China"
            },
            {
                "name": "WANG Jun-an",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "TAO Xiao-xiao",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "Zhan Li",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Harbin Institute of Technology(Harbin Institute of Technology,Harbin Inst. of Technol.),Harbin,China"
            }
        ],
        "venue": "Harbin Gongye Daxue Xuebao/Journal of Harbin Institute of Technology",
        "year": 2010
    },
    "OZ8wpGiE": {
        "id": "OZ8wpGiE",
        "title": "Rapid Start-Up of Biofilter for Removal of Iron and Manganese from Groundwater",
        "abstract": "",
        "keywords": [
            "biofilter",
            "groundwater",
            "iron removal",
            "manganese removal",
            "start-up procedure",
            "iron",
            "ground water"
        ],
        "authors": [
            {
                "name": "Hui Ping Zeng",
                "org": ""
            },
            {
                "name": "Dong Li",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            }
        ],
        "venue": "Advanced Materials Research",
        "year": 2010
    },
    "XCZ1RKyM": {
        "id": "XCZ1RKyM",
        "title": "Optimal operation of multi-storage tank multi-source system based on storage policy",
        "abstract": "A two-stage method is developed to solve a new class of multi-storage tank multi-source (MTMS) systems. In the first stage,\n the optimal storage policy of each tank is determined according to the electricity tariff, and the ground-level storage tank\n is modeled as a node. In the second stage, the genetic algorithm, combined with a repairing scheme, is applied to solve the\n pump scheduling problem. The objective of the pump scheduling problem is to ensure that the required volume is adequately\n provided by the pumps while minimizing the operation cost (energy cost and treatment cost). The decision variables are the\n settings of the pumps and speed ratio of variable-speed pumps at time steps of the total operational time horizon. A mixed\n coding methodology is developed according to the characteristics of the decision variables. Daily operation cost savings of\n approximately 11% are obtained by application of the proposed method to a pressure zone of S. Y. water distribution system\n (WDS), China.",
        "keywords": [
            "genetic algorithm",
            "repairing scheme",
            "storage policy",
            "multi-storage tank system",
            "pump scheduling",
            "scheduling problem"
        ],
        "authors": [
            {
                "name": "haien",
                "org": "harbin institute of technology"
            },
            {
                "name": "fang",
                "org": "harbin institute of technology"
            },
            {
                "name": "jie",
                "org": "harbin institute of technology"
            },
            {
                "name": "zhang",
                "org": "harbin institute of technology"
            },
            {
                "name": "jinliang",
                "org": "harbin institute of technology"
            },
            {
                "name": "gao",
                "org": "harbin institute of technology"
            }
        ],
        "venue": "Journal of Zhejiang University Science",
        "year": 2010
    },
    "BXnE9CzL": {
        "id": "BXnE9CzL",
        "title": "Efficient star-up of partial nitrification process in sequencing batch biofilm reactor with domestic wastewater at room temperature",
        "abstract": "This study focused on star-up of the partial nitrification in sequencing batch biofilm reactor (SBBR) with domestic wastewater at room temperature. No significant nitrate formation was observed during the full period of operation and the nitrite oxidizing bacteria (NOB) was successfully outcompeted. When influent ammonium concentration decreased from 200mg/L to 80mg/L, a stable influent at a ratio of 1.03 NO2-N/NH4-N was produced after 44 continuous cycles(33d)and that indicated partial nitrification achievement. A recommended start-up strategy based on high FA concentration and aeration control was proposed to achieve partial nitrification with low ammonium strength wastewater at room temperature. © (2011) Trans Tech Publications, Switzerland.",
        "keywords": [
            "ammonia oxidizing bacteria (aob)",
            "domestic wastewater",
            "partial nitrification",
            "sequencing batch biofilm reactor (sbbr)"
        ],
        "authors": [
            {
                "name": "Taotao Zeng",
                "org": "Harbin Institute of Technology(Harbin Institute of Technology,Harbin Inst. of Technol.),Harbin,China"
            },
            {
                "name": "Dong Li",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Harbin Institute of Technology(Harbin Institute of Technology,Harbin Inst. of Technol.),Harbin,China"
            }
        ],
        "venue": "Advanced Materials Research",
        "year": 2011
    },
    "SmPLTAhE": {
        "id": "SmPLTAhE",
        "title": "Factors of the rapid startup for nitrosation in sequencing batch reactor",
        "abstract": "The approach and factors for realizing the rapid startup of nitrosation were researched at the low level of dissolved oxygen (DO) in sequencing batch reactor (SBR). The main parameters of the reactor were controlled as follows: DO were 0.15-0.40 mg/L, pH values kept from 7.52 to 8.30, temperature maintained at 22.3-27.1°C, and time of aeration was 8 hours. The purpose of rapid startup for nitrosation was achieved after 57 cycles (36 d) with the alternative influent of high and low ammonium wastewater (the mean values were 245.28 mg/L and 58.08 mg/L respectively) in a SBR, and the nitrosation rate was even 100%. Factors of accumulation of nitrite were investigated and the effects of DO and pH were analyzed during the startup for nitrosation. The results showed that it could improve the efficiency of nitrosation when DO concentration was increased appropriately. The activity of nitrite oxidizing bacteria (NOB) was recovered gradually when DO was higher than 0.72 mg/L. The key factor of controlling nitrosation reaction was the concentration of free ammonia (FA), while the final factor was the concentration of DO. pH was a desired controlling parameter to show the end of nitrification in a SBR cycle, while DO concentration did not indicate the finishing of SBR nitrification accurately because it increased rapidly before ammonia nitrogen was oxidized absolutely.",
        "keywords": [
            "Dissolved oxygen (DO)",
            "Free ammonia (FA)",
            "Nitrosation",
            "PH",
            "Sequencing batch reactor (SBR)"
        ],
        "authors": [
            {
                "name": "Dong Li",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "Xiaoxiao Tao",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "Zhan Li",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "JunAn Wang",
                "org": "Research and Development Center(Research and Development Center),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Harbin Institute of Technology(Harbin Institute of Technology,Harbin Inst. of Technol.),Harbin,China"
            }
        ],
        "venue": "Huanjing Kexue/Environmental Science",
        "year": 2011
    },
    "1KivtWYI": {
        "id": "1KivtWYI",
        "title": "Research on the rapid start-up and optimization of parameters for nitrosation at room temperature",
        "abstract": "The nitrosation rate was around 85% after 33 continuous cycles(20 d) with the alternative influent of high and low ammonium wastewater in a sequencing batch reactor(SBR) which low oxygen(0.15-0.40 mg/L). The growth of nitrobacteria was inhibited successfully which led to a steady and high accumulation of nitrite. The effects of five different DO concentrations were investigated with low ammonium influent on nitrite accumulation. The results clearly showed that ratios of the nitrite accumulation rate [Δc(NO2 --N)/t] to that of nitrate accumulation [Δc(NO3 --N)/t] were 16.37, 17.28, 17.69, 7.29, 3.64 at five different DO concentrations(0.27, 0.48, 0.72, 0.99, 1.47 mg/L ), respectively. The corresponding nitrosation rates were 95.28%, 94.49%, 94.64%, 87.84% and 78.63% at the temperature of 22.3-27.6°C. Results showed that a maximum of 94% nitrosation efficiency was reached with average DO concentration of 0.72 mg/L and the aeration time of 4 hours at normal temperature after 23 continuous cycles(13 d).",
        "keywords": [
            "Dissolved oxygen",
            "Free ammonia",
            "Nitrosation",
            "Room temperature",
            "Sequencing batch reactor(SBR)"
        ],
        "authors": [
            {
                "name": "Dong Li",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "TAO Xiao-xiao",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "Zhan Li",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "WANG Jun-an",
                "org": "Research and Development Center(Research and Development Center),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Harbin Institute of Technology(Harbin Institute of Technology,Harbin Inst. of Technol.),Harbin,China"
            }
        ],
        "venue": "Huanjing Kexue/Environmental Science",
        "year": 2011
    },
    "F8KL3C6N": {
        "id": "F8KL3C6N",
        "title": "Distribution and genetic diversity of functional microorganisms in different CANON reactors.",
        "abstract": "Completely autotrophic nitrogen removal over nitrite (CANON) has been regarded as an efficient and economical process for nitrogen removal from wastewater. The distribution and genetic diversity of the functional microorganisms in five lab-scale CANON reactors have been investigated by using some molecular biology methods. Nitrosomonas-like aerobic ammonium oxidizing bacteria (AerAOB) and Candidatus Brocadia-related anaerobic ammonium oxidizing bacteria (AnAOB) were detected as predominant functional microbes in the five reactors while Nitrobacter-like nitrite oxidizing bacteria (NOB) existed only in the systems operated at ambient temperature. Communities of AerAOB and AnAOB were almost similar among the five reactors while the distribution of the functional microbes was either scattered or densely packed. Meanwhile, this study has demonstrated the feasibility of starting up CANON by inoculating conventional activated sludge in low ammonium content at ambient temperature.",
        "keywords": [
            "canon",
            "distribution",
            "diversity",
            "fish",
            "pcr-dgge"
        ],
        "authors": [
            {
                "name": "Tao Liu",
                "org": "Harbin Institute of Technology(Harbin Institute of Technology,Harbin Inst. of Technol.),Harbin,China"
            },
            {
                "name": "Dong Li",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "Huiping Zeng",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "Xiangkun Li",
                "org": "Harbin Institute of Technology(Harbin Institute of Technology,Harbin Inst. of Technol.),Harbin,China"
            },
            {
                "name": "Yuhai Liang",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "Xiaoyan Chang",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Harbin Institute of Technology(Harbin Institute of Technology,Harbin Inst. of Technol.),Harbin,China"
            }
        ],
        "venue": "Bioresource technology",
        "year": 2012
    },
    "d3n0ZifS": {
        "id": "d3n0ZifS",
        "title": "Biodiversity and quantification of functional bacteria in completely autotrophic nitrogen-removal over nitrite (CANON) process.",
        "abstract": "The research was conducted to investigate the microbial diversity and population with the different concentration of NH(4)(+)-N in a biofilm reactor filled with volcanic filter for completely autotrophic nitrogen-removal over nitrite (CANON) process. The reactor had an excellent performance with the decreasing of NH(4)(+)-N concentration from 400 to 200 mg L(-1) while NH(4)(+)-N removal loading reduced at the NH(4)(+)-N concentration of 100 mg L(-1). Biodiversity analysis indicated that Nitrosomonas related aerobic ammonia oxidizing bacteria (AOB) and Planctomycetales-like anaerobic ammonia oxidizing (anammox) bacteria were dominant functional bacteria. Despite the different influent NH(4)(+)-N concentration, anammox bacteria had a low and stable biodiversity, which was not the same to AOB. With the concentration reduction of influent NH(4)(+)-N, the estimates of total bacteria population ranged between 2.29×10(11) and 1.44×10(12) copies mg(-1) total DNA, and the quantity of AOB decreased while anammox bacteria kept stable. The population of Nitrospira increased and little Nitrobacter was detected during the experiment.",
        "keywords": [
            "real-time pcr",
            "quantification",
            "canon",
            "biodiversity",
            "pcr-dgge"
        ],
        "authors": [
            {
                "name": "Tao Liu",
                "org": "Harbin Institute of Technology(Harbin Institute of Technology,Harbin Inst. of Technol.),Harbin,China"
            },
            {
                "name": "Dong Li",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "Huiping Zeng",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "Xiangkun Li",
                "org": "Harbin Institute of Technology(Harbin Institute of Technology,Harbin Inst. of Technol.),Harbin,China"
            },
            {
                "name": "Taotao Zeng",
                "org": "Harbin Institute of Technology(Harbin Institute of Technology,Harbin Inst. of Technol.),Harbin,China"
            },
            {
                "name": "Xiaoyan Chang",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "Yan'an Cai",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Harbin Institute of Technology(Harbin Institute of Technology,Harbin Inst. of Technol.),Harbin,China"
            }
        ],
        "venue": "Bioresource technology",
        "year": 2012
    },
    "2d9XWSeI": {
        "id": "2d9XWSeI",
        "title": "Influential factors of the rapid startup of nitrosation at ambient temperature in SBR for domestic sewage",
        "abstract": "The nitrosation rate was around 85% after 33 continuous cycles (20d) with the alternative influent of high and low ammonium wastewater in a sequencing batch reactor (SBR) under low oxygen (0.15~0.40mg/L). The growth of nitrobacteria was inhibited successfully which led to steady and high accumulation of nitrite. Factors of accumulation of nitrite were investigated and the effects of DO and pH were analyzed during the startup for nitrosation. The results showed that it could improve the efficiency of nitrosation when DO concentration was increased appropriately. The activity of nitrite oxidizing bacteria (NOB) was recovered gradually when DO was higher than 0.72mg/L. The key factor of nitrosation reaction was the concentration of free ammonia (FA), while the final factor was the concentration of DO. pH was a desired controlling parameter showing the end of nitrification in a SBR cycle, while DO concentration did not indicate the end of SBR nitrification accurately because it increased rapidly before ammonia nitrogen was oxidized absolutely. © (2013) Trans Tech Publications, Switzerland.",
        "keywords": [
            "ambient temperature",
            "domestic sewage",
            "nitrosation",
            "sbr",
            "short-cut nitrification",
            "start-up"
        ],
        "authors": [
            {
                "name": "Di Wu",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "Dong Li",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "Xiaoxiao Tao",
                "org": "Zhengzhou Coal Industry Design and Research Institute Co., Ltd.(Coal Industry Zhengzhou Design and Research Institute,Zhengzhou Coal Industry Design and Research Institute Co., Ltd.,Zheng Zhou Design and Research Institute of Coal Industry Co. Ltd.,Zhengzhou Design and research institute of coal industry stock co.,Zhengzhou Design Research Institutes of Coal Inductry CO. LTD.),Zhengzhou,China"
            },
            {
                "name": "Huiping Zeng",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Harbin Institute of Technology(Harbin Institute of Technology,Harbin Inst. of Technol.),Harbin,China"
            }
        ],
        "venue": "Advanced Materials Research",
        "year": 2013
    },
    "qrAb9pzW": {
        "id": "qrAb9pzW",
        "title": "Influence of alkalinity on partial nitrification treating domestic sewage and the microbial community in MBR",
        "abstract": "Partial nitrification (PN) was rapidly started-up in a sequencing batch membrane bioreactor(MBR) treating domestic wastewater with low temperature (11~15°C), the influence of alkalinity on PN process and the feasibility to control the ratio of nitrite to ammonia in effluent were investigated through changing the ratio of Alkalinity/ammonia in influent. Results showed that effluent ratio can be controlled flexibly with the liner relationship between ammonia conversion and the ratio of alkalinity to ammonia when alkalinity is insufficient, whereas, that could be effectively achieved by the indicator role of alkalinity on nitrite. Phylogenetic results indicated the predominance of Nitrosomonas and the absence of the Nitrosospira in the condition of insufficient alkalinity, which was consistent with the SEM results. FISH results suggested that lack of alkalinity presented little impact on the relative quantity of AOB. © (2013) Trans Tech Publications, Switzerland.",
        "keywords": [
            "alkalinity",
            "domestic sewage",
            "membrane bioreactor (mbr)",
            "partial nitrification"
        ],
        "authors": [
            {
                "name": "Xiaojing Zhang",
                "org": "Harbin Institute of Technology(Harbin Institute of Technology,Harbin Inst. of Technol.),Harbin,China"
            },
            {
                "name": "Dong Li",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "Yulong Zhang",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "Yongping He",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Harbin Institute of Technology(Harbin Institute of Technology,Harbin Inst. of Technol.),Harbin,China"
            }
        ],
        "venue": "Advanced Materials Research",
        "year": 2013
    },
    "M5MRzJoP": {
        "id": "M5MRzJoP",
        "title": "Rapid start-up of biological purifying filter of groundwater containing high concentration of iron and manganese associated ammonia nitrogen",
        "abstract": "Biological manganese removal process has a problem of long start-up period, when it is adopted to purify groundwater containing high concentration of iron, manganese and ammonia nitrogen. In order to investigate the effect of circulation reflux on start-up, three starting modes with varying reflux ratio, constant reflux ratio and no reflux were adopted in three same filters. Results showed that the total iron, manganese and ammomia nitrogen in effluent of the three filters was below 0.3 mg/L, 0.05 mg/L and 0.2 mg/L on 51, 61 and 82 day, respectively; Variation of iron, manganese and ammonia nitrogen removal along the filter showed that the iron was removed mainly in the depth of 0-0.4 m, the manganese was adsorbed by manganese sand at the beginning and biological manganese removal was improved gradually after ammonia nitrogen reduced to be low enough. The circulation reflux is an effective way to shorten the start-up period of biological manganese removal process with high concentration of iron, manganese and ammonia nitrogen.",
        "keywords": [
            "Biological manganese removal",
            "Circulation reflux",
            "Groundwater",
            "High concentration of iron",
            " manganese and ammonia nitrogen",
            "Start-up"
        ],
        "authors": [
            {
                "name": "Qingfeng Cheng",
                "org": "Harbin Institute of Technology(Harbin Institute of Technology,Harbin Inst. of Technol.),Harbin,China"
            },
            {
                "name": "Dong Li",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "Xiangkun Li",
                "org": "Harbin Institute of Technology(Harbin Institute of Technology,Harbin Inst. of Technol.),Harbin,China"
            },
            {
                "name": "Xiaojing Zhang",
                "org": "Harbin Institute of Technology(Harbin Institute of Technology,Harbin Inst. of Technol.),Harbin,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Harbin Institute of Technology(Harbin Institute of Technology,Harbin Inst. of Technol.),Harbin,China"
            }
        ],
        "venue": "Harbin Gongye Daxue Xuebao/Journal of Harbin Institute of Technology",
        "year": 2013
    },
    "mhOrEJxq": {
        "id": "mhOrEJxq",
        "title": "Start-up of ANAMMOX bio-filter for domestic secondary effluent in ambient temperature",
        "abstract": "The start-up of ANAMMOX bio-filter for domestic secondary effluent was investigated in ambient temperature. The raw water for ANAMMOX bio-filter was the effluent from an anoxic-aerobic (A/O) phosphorous removal system. Nitrification biofilm was successfully transformed into ANAMMOX biofilm during 7 months, with the induction of added nitrite, hydrazine and oxyammonia. The highest TN removal rate reached 6.8 kg/m3/d during start-up, with observed growth rate of 0.0018 h-1 and doubling time of 16.45 d. © (2013) Trans Tech Publications, Switzerland.",
        "keywords": [
            "ambient temperature",
            "anammox",
            "bio-filter nitrification biofilm",
            "domestic sewage"
        ],
        "authors": [
            {
                "name": "Di Wu",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "Dong Li",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "Weinan Gao",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "Huiping Zeng",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Harbin Institute of Technology(Harbin Institute of Technology,Harbin Inst. of Technol.),Harbin,China"
            }
        ],
        "venue": "Advanced Materials Research",
        "year": 2013
    },
    "sNvhsY9P": {
        "id": "sNvhsY9P",
        "title": "Influence of backwashing time on iron, manganese, ammonia and turbidity removal using a pilot-scale biological filter",
        "abstract": "Backwashing time is one of the most critical operational parameters for biological filter. In order to investigate the effect of backwashing time on iron, manganese, ammonia and turbidity removal, three backwashing time (5 min, 4 min and 3 min) were adopted. Results showed that the average concentration of total iron, manganese and ammonia in effluent was 0.025 mg/L, 0.007 mg/L, and 0.022 mg/L; 0.012 mg/L, 0.001 mg/L and 0.017 mg/L; 0.013 mg/L, 0.000 mg/L and 0.016 mg/L, respectively, which illustrated varying backwashing time had little influence on the removal efficiency of them. The turbidity in effluent was 0.28 NTU, 0.38 NTU, 0.57 NTU, respectively. The shorter backwashing time, the higher turbidity in effluent. Turbidity was almost completely removed in 0~0.4m of the media. After backwashing, the turbidity in effluent was decreased to less than 1 NTU in 40 min, droped to less than 0.5 NTU in 90 min. © (2013) Trans Tech Publications, Switzerland.",
        "keywords": [
            "backwashing time",
            "biological filter",
            "groundwater",
            "iron",
            "manganese and ammonia",
            "turbidity",
            "manganese",
            "ground water"
        ],
        "authors": [
            {
                "name": "Qingfeng Cheng",
                "org": "Harbin Institute of Technology(Harbin Institute of Technology,Harbin Inst. of Technol.),Harbin,China"
            },
            {
                "name": "Dong Li",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "Xiangkun Li",
                "org": "Harbin Institute of Technology(Harbin Institute of Technology,Harbin Inst. of Technol.),Harbin,China"
            },
            {
                "name": "Lingwei Meng",
                "org": "Harbin Institute of Technology(Harbin Institute of Technology,Harbin Inst. of Technol.),Harbin,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Harbin Institute of Technology(Harbin Institute of Technology,Harbin Inst. of Technol.),Harbin,China"
            }
        ],
        "venue": "Advanced Materials Research",
        "year": 2013
    },
    "V9SUykRS": {
        "id": "V9SUykRS",
        "title": "Start-up and stability of Anammox bioreactor at normal temperature and low substrate concentration",
        "abstract": "In this study, lab-scale up-flow biofilter reactor fed with the oxidation ditch backflow sludge was used to start-up the anaerobic ammonium oxidation (Anammox) process under normal temperature and low substrate concentration. Firstly, aerobic nitration biofilm was cultivated, and then Anammox biofilm was cultivated under anaerobic condition. The influent pH of 7.50~7.80, NH4 +-N of 30~40 mg/L, NO2 --N of 35~50 mg/L and temperature of 20~25°C were controlled in this study. After 224 days of operation, the Anammox reactor was started up successfully. In the stable operation stage, the average concentration of effluent NO2 --N and NH4 +-N were 1.4 mg/L and 4.6 mg/L, respectively, the removal rate of NO2 --N and NH4 +-N were 95.3% and 90.1%, respectively. The removal proportion of NO2 --N/NH4 +-N was 1~1. 8:1 and the main focused on 1.4~1.5:1. The removal volume loading rate of NO2 --N and NH4 +-N were 104.2 mg/(L·d) and 146.0 mg/(L·d), respectively.",
        "keywords": [
            "Anammox",
            "Low substrate",
            "Normal temperature",
            "Stability",
            "Start-up"
        ],
        "authors": [
            {
                "name": "Linlin Bao",
                "org": "Henan Normal University(Henan Normal University),Xinxiang,China"
            },
            {
                "name": "Jianguo Zhao",
                "org": "Henan Normal University(Henan Normal University),Xinxiang,China"
            },
            {
                "name": "Xiaokai Li",
                "org": "Henan Normal University(Henan Normal University),Xinxiang,China"
            },
            {
                "name": "Dong Li",
                "org": "Henan Normal University(Henan Normal University),Xinxiang,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Harbin Institute of Technology(Harbin Institute of Technology,Harbin Inst. of Technol.),Harbin,China"
            }
        ],
        "venue": "Chinese Journal of Environmental Engineering",
        "year": 2013
    },
    "Lg0iZv62": {
        "id": "Lg0iZv62",
        "title": "Effect of phosphate on Ananmmox at low substrate and normal temperature",
        "abstract": "The influence of phosphate concentration on anaerobic ammonia oxidation (Anammox) reaction was investigated using a lab-scale up-flow Anammox biofilter reactor in this study. The experimental conditions were controlled at temperature of (25± 1)°C, pH values of 7.5~7.7, the concentration of NH4 +-N was 30~45 mg/L, NO2 --N was 30~45 mg/L and COD was less than 10 mg/L. The results showed that phosphate concentration had no effect on the Anammox reactor when TP < 5 mg/L, the NH4 +-N removal was inhibited and removal rate of TN was reduced when TP was between 5 mg/L and 7.5 mg/L. The systems recovered quickly when stop dosing phosphate.",
        "keywords": [
            "Anammox",
            "Low substrate",
            "Normal temperature",
            "Phosphate"
        ],
        "authors": [
            {
                "name": "Linlin Bao",
                "org": "Henan Normal University(Henan Normal University),Xinxiang,China"
            },
            {
                "name": "Gangqiang Li",
                "org": "Henan Normal University(Henan Normal University),Xinxiang,China"
            },
            {
                "name": "Dong Li",
                "org": "Henan Normal University(Henan Normal University),Xinxiang,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Harbin Institute of Technology(Harbin Institute of Technology,Harbin Inst. of Technol.),Harbin,China"
            }
        ],
        "venue": "Chinese Journal of Environmental Engineering",
        "year": 2013
    },
    "sR1wsejC": {
        "id": "sR1wsejC",
        "title": "[Effect of Seeding Single/Mixed Sludge on Rapid Start-up of an ANAMMOX Reactor].",
        "abstract": "The experiment explored the effect of different seeding sludge on the rapid start-up of an anaerobic ammonium oxidation (ANAMMOX) reactor by seeding a single type of denitrified granular sludge and a mixed sludge composed of denitrified granular sludge and aerobic nitrification sludge (the volume ratio of the mixed sludge was 2:1) in two sequencing batch reactors (SBR), R0 and R1, respectively. The results indicated that R0 was started up successfully on day 64 with a nitrogen removal rate (NRR) of 0.26 kg·(m·d), while R1 was started up by day 47 with a NRR of 0.30 kg·(m·d), which was shorter than R0 by 17 d. In the enrichment stage, reddish sludge appeared in R1, and the characteristics of anaerobic ammonium oxidation of the system were more obvious than in R0. After the reactor was started up successfully, the stoichiometric ratio of R0 was 1.20 and 0.34, respectively, and the stoichiometric ratio of R1 was 1.26 and 0.21, which was closer to the theoretical values of 1.32 and 0.26. The mixed liquor suspended solids (MLSS) and mixed liquor volatile suspended solids (MLVSS) of R0 were restored to 51% (4.2 g·L) and 38% (2.3 g·L)of the initial seeding sludge, respectively, while the MLSS and MLVSS of R1 were restored to 54% (4.4 g·L) and 42% (2.6 g·L),which was higher than R0. It can be speculated that the proliferation rate of AnAOB in R1 was faster than in R0. Seeding mixed sludge can accelerate the start-up process of anaerobic ammonium oxidation with more stable N-removal performance.",
        "keywords": [
            "MLSS",
            "MLVSS",
            "anaerobic ammonium oxidation (ANAMMOX)",
            "mixed sludge",
            "rapid start up",
            "stoichiometric ratio"
        ],
        "authors": [
            {
                "name": "Ze-Wen Zhang",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Dong Li",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Jie Zhang",
                "org": "State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin 150090, China."
            },
            {
                "name": "Yue-Zhou Guo",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Shuai Li",
                "org": "State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin 150090, China."
            }
        ],
        "venue": "Huan jing ke xue= Huanjing kexue",
        "year": 2017
    },
    "5I47MSeD": {
        "id": "5I47MSeD",
        "title": "[Laboratory-scale CANON Processes Applied to Wastewater Treatment Plants].",
        "abstract": "A laboratory-scale completely autotrophic nitrogen removal over nitrite (CANON) process was operated in a municipal wastewater treatment plant (WWTP). Sewage effluent treated by the anaerobic/oxic (A/O) process and was used to operate a WWTP to obtain the initial substance for the start-up of a CANON filter reactor. On the 48th day, the ammonia removal rate was measured at greater than 90% in successive 10 d samples and the nitrogen removal rate was greater than 70%. The CANON filter was successful at start up. From the 49 to the 129 day, the dissolved oxygen in the reactor was maintained at fairly low concentration of 0.2-0.5 mg·L. The effluent contained nearly no ammonia and the maximum total nitrogen (TN) concentration was 15.6 mg·L, which exceeded the national Class 1A Discharge Standards for pollutants from municipal wastewater treatment plants. Nitrite oxidizing bacteria (NOB) proliferated excessively in the reactor. Backwash was implemented on 129th, 169th and 213th days. The nitrogen removal rate was more than 70% for a long time and TN concentration in effluent was below 12 mg·L. The nitrogen concentration in effluent fitted the national Class 1A Discharge Standards and the NOB were effectively inhibited. These results show that backwash has negligible on the structure of filter and its impact on the thickness of the bio-membrane and its functional bacteria was small, however, it is capable of effectively inhibiting the activity of the NOB. Periodically backwashing can be utilized as an engineering application to maintain stable operation of the CANON process.",
        "keywords": [
            "CANON",
            "backwash",
            "domestic wastewater",
            "filter",
            "nitrite oxidizing bacteria"
        ],
        "authors": [
            {
                "name": "Dong Li",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Shi-Xun Zhao",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Jun-An Wang",
                "org": "Technology Research and Development Center, Beijing Sander Environmental Group, Beijing 101102, China."
            },
            {
                "name": "Jin-Feng Zhu",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Hong-Wei Guan",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Jie Zhang",
                "org": "State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin 150090, China."
            }
        ],
        "venue": "Huan jing ke xue= Huanjing kexue",
        "year": 2017
    },
    "0l6JdIfn": {
        "id": "0l6JdIfn",
        "title": "[Removal of High Concentration of Iron, Manganese and Ammonia Nitrogen from Low Temperature Groundwater Using Single Bio-filter].",
        "abstract": "A pilot-scale bio-filter was constructed for the removal of high concentrations of iron (TFe 9.0-12.0 mg·L, Fe(Ⅱ) 6.5-8.0 mg·L), manganese (1.9-2.1 mg·L), and ammonia nitrogen (1.4-1.7 mg·L) simultaneously from low temperature (5-6℃) groundwater in a plant. The results showed that iron was removed at the beginning of the bio-filter start-up, and manganese and ammonia nitrogen were removed on day 72 and day 75, respectively. The start-up period was influenced by the culture temperature and the raw water quality. For higher filtration rates, the removal of manganese was lower. When the filtration rate was more than 1.0 m·h, the maximum removal of manganese was about 3.0 mg·L. Manganese was the limiting factor for the increase of filtration rate, and the maximum filtration rate of the single bio-filter was 4.5 m·h. When the filtration rate was less than 6.0 m·h, the removal of ammonia nitrogen was about 1.5 mg·L, which was not affected by the filtration rate. Dissolved oxygen (DO) deficiency led to failure with the removal of more ammonia nitrogen. The required thickness of the bio-filter required for purification increased as the concentration of manganese and ammonia nitrogen increased when DO was sufficient. The removed iron, manganese, and ammonia nitrogen move to the depth of the filter layer, and there will be \"manganese dissolution\" when the filtration rate is increased. Iron and ammonia nitrogen in the filter layer can be oxidized and removed simultaneously. Manganese is oxidized and removed after the iron and ammonia nitrogen. The effective oxidation and removal section of manganese, iron, and ammonia nitrogen are obviously graded.",
        "keywords": [
            "filtration rate",
            "groundwater",
            "high concentration of iron",
            "manganese and ammonia nitrogen",
            "low temperature",
            "oxidation and removal section",
            "single bio-filter",
            "start-up",
            "thickness of filter layer"
        ],
        "authors": [
            {
                "name": "Dong Li",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Rui-Hua Cao",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Hang Yang",
                "org": "State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin 150090, China."
            },
            {
                "name": "Liu-Yu Wang",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Jie Zhang",
                "org": "State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin 150090, China."
            },
            {
                "name": "Hui-Ping Zeng",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, Beijing University of Technology, Beijing 100124, China."
            }
        ],
        "venue": "Huan jing ke xue= Huanjing kexue",
        "year": 2017
    },
    "89ljXDD6": {
        "id": "89ljXDD6",
        "title": "[Lab-scale SNAD Process in Wastewater Treatment Plant].",
        "abstract": "Outside the municipal waste water treatment plant(WWTP) which located in Mentougou District, Beijing, the effluent of the anoxic/oxic(A/O) phosphorus removal process served as the substrate to operate a completely autotrophic nitrogen removal over nitrite(CANON) filter reactor.. After the reactor was successfully activated, glucose was added to the influent as the organic carbon source. The simultaneous partial nitrification, anaerobic ammonium oxidation (ANAMMOX), and denitrification (SNAD) process was started to study the effect of SNAD filter on sewage treatment. The results showed that from 119 d to 128 d, the ammonia removal rate of the CANON process was more than 95%, and the maximum total nitrogen concentration in the effluent was 13.0 mg·L. Total nitrogen concentration surpassed the 1A level of the Integrated Discharge Standard of Water Pollutants applied in Beijing City. The SNAD process was started by adding glucose to the influent at 129 d. The total nitrogen removal rate of this process was about 85% at 133-187 d, and the total nitrogen concentration in the effluent was 5.5-7.3 mg·L. The filter plugged up at 195 d, and backwash was utilized at 196 d. During the subsequent 30 d, the total nitrogen removal rate of the reactor was greater than 85%, and the total nitrogen concentration in the effluent remained at 6.2-7.2 mg·L. Compared with the CANON process, the SNAD process improved the total nitrogen removal rate and reduced the total nitrogen concentration of the effluent by 6 mg·L. The ammonia and total nitrogen concentrations in effluent satisfied the 1A level of the Integrated Discharge Standard of Water Pollutants.",
        "keywords": [
            "bio-membrane",
            "filter",
            "organic carbon source",
            "sewage",
            "simultaneous partial nitrification",
            "ANAMMOX and denitrification(SNAD)"
        ],
        "authors": [
            {
                "name": "Dong Li",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, College of Architecture and Civil Engineering of Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Ya-Qian Cui",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, College of Architecture and Civil Engineering of Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Shi-Xun Zhao",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, College of Architecture and Civil Engineering of Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Zhi-Cheng Liu",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, College of Architecture and Civil Engineering of Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Jie Zhang",
                "org": "State Key Laboratory of Urban Water Resource and Environment, School of Environment, Harbin Institute of Technology, Harbin 150090, China."
            }
        ],
        "venue": "Huan jing ke xue= Huanjing kexue",
        "year": 2018
    },
    "TNRMdd98": {
        "id": "TNRMdd98",
        "title": "[Start-up and Operation of Biofilter Coupled Nitrification and CANON for the Removal of Iron, Manganese and Ammonia Nitrogen].",
        "abstract": "A pilot-scale bio-filter coupled nitrification and CANON was started up to remove iron, manganese and ammonia nitrogen from groundwater in a plant, and the main removal route of ammonia nitrogen was analyzed. The experiment showed that the bio-filter could be started up successfully and achieved stable operation after 164 days of culture development. The value of △NH-N/△NO-N was 1.49, and the oxidation and removal of Fe(Ⅱ), Mn(Ⅱ), and NH-N were (9.87±1.17), (2.25±0.06), and (1.51±0.06) mg·L, respectively. The calculation based on the quantitative relationship between nitrogen conservation and dissolved oxygen (DO) measurement indicated that the contribution of CANON to NH-N removal was 33.48%-38.87%, and the average ratio of ammonia nitrogen removal amount to DO was 1:3.79-1:3.94. The removal ratio of ammonia nitrogen was lower with lower temperature.",
        "keywords": [
            "CANON",
            "ammonia nitrogen",
            "dissolved oxygen",
            "iron and manganese",
            "nitrogen conservation"
        ],
        "authors": [
            {
                "name": "Dong Li",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Rui-Hua Cao",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Hang Yang",
                "org": "State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin 150090, China."
            },
            {
                "name": "Yan-Ju Wang",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Sai-Sai Lü",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Jie Zhang",
                "org": "State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin 150090, China."
            }
        ],
        "venue": "Huan jing ke xue= Huanjing kexue",
        "year": 2018
    },
    "443wZhlz": {
        "id": "443wZhlz",
        "title": "[Effect of Aerobic/Phosphorus Granules on Start-up of Partial Nitrification Granular Sludge].",
        "abstract": "The different effects of additional aerobic granules (AGs) and phosphorus removal granules (PRGs) on the start-up and stable operation of partial nitrification granular sludge (PNGS) were compared at room temperature(22-28℃). The results showed that in the first stage (days 0-22), partial nitrification was accomplished on day 19 for the three reactors (R1, R2, and R3). In the second stage (days 23-56), 20% AGs and 20% PRGs were added to R2 and R3 to induce PNGS. The start-up of the granules of the three reactors was successfully achieved. The mean particle sizes of R1, R2, and R3 reached 412 μm at day 76, 468 μm at day 42, and 400 μm at day 56. In the third stage (days 57-108), because the influent ammonia load increased from 0.4 kg·(m·d) to 0.5 kg·(m·d) and the COD load increased from 0.2 kg·(m·d) to 0.5 kg·(m·d), the mean particle sizes of R1 and R2 increased significantly. The average particle sizes of R1 and R2 reached 689 μm and 893 μm by the end of the operation (day 108), but sludge expansion occurred in R3. The inoculation of either AGs or PRGs could quickly achieve granulation, but the PNGS inoculated with the AGs could adapt to higher C/N and be more tolerable to shock loads and long-term stable operation.",
        "keywords": [
            "COD load",
            "aerobic granules",
            "ammonia nitrogen load",
            "partial nitrification granular sludge",
            "phosphorus removal granules"
        ],
        "authors": [
            {
                "name": "Dong Li",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Yue-Zhou Guo",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Mei-Zhong Cao",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Ze-Wen Zhang",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Shuai Li",
                "org": "State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin 150090, China."
            },
            {
                "name": "Jie Zhang",
                "org": "State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin 150090, China."
            }
        ],
        "venue": "Huan jing ke xue= Huanjing kexue",
        "year": 2018
    },
    "FB1Qtczm": {
        "id": "FB1Qtczm",
        "title": "[Effect of Carbon Source on Lab-scale SAD Process in a Wastewater Treatment Plant].",
        "abstract": "Lab-scale anaerobic ammonia oxidation and denitrification (SAD) processes were operated simultaneously in a municipal waste water treatment plant (WWTP). Sewage treated by the A/O and nitrification process was used as the substance to start up an anaerobic ammonia oxidation filter reactor. Adding glucose and sodium propionate to influent was used as the substance to start up the SAD filter reactor after the successful start-up of the ANAMMOX reactor. The SAD process performed well with an average total nitrogen concentration in the effluent of 6.41 mg·L when 30 mg·L glucose was added to the effluent sewage at ambient temperature. Compared with the ANAMMOX process, the total nitrogen concentration in the effluent from the SAD process decreased 42%. The stability of the SAD process was destroyed and the SAD process turned into a denitrification process when 30 mg·L glucose was added in the influent sewage in a low temperature environment. In normal and low temperature environments, the SAD process functioned well, and the average total nitrogen concentration of the effluent was 6.54 mg·L when 30 mg·L sodium propionate was added in the influent sewage. Compared with glucose, sodium propionate had little influence on the SAD process.",
        "keywords": [
            "ANAMMOX",
            "carbon source",
            "denitrification",
            "filter",
            "sewage"
        ],
        "authors": [
            {
                "name": "Dong Li",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Shi-Xun Zhao",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Jun-An Wang",
                "org": "Technology Research and Development Center, Beijing Sander Environmental Group, Beijing 101102, China."
            },
            {
                "name": "Jin-Feng Zhu",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Hong-Wei Guan",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Jie Zhang",
                "org": "State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin 150090, China."
            }
        ],
        "venue": "Huan jing ke xue= Huanjing kexue",
        "year": 2018
    },
    "EuE4e4u3": {
        "id": "EuE4e4u3",
        "title": "[Arsenic(Ⅴ) Removal by Granular Adsorbents Made from Backwashing Residuals from Biofilters for Iron and Manganese Removal].",
        "abstract": "Granular adsorbents for arsenic removal (GA) made from the backwashing residuals from iron and manganese removal biofilters for groundwater were characterized and examined as an arsenate sorbent. The GA were characterized by SEM-EDS microscopy, X-ray diffraction (XRD), and BET surface area measurement. The results showed that the GA had rough surfaces, developed pores, and were mainly amorphous, with small fractions of crystalline quartz and hematite. The surface area of the GA, which consists of many mesopores, was 43.8 m·g. The kinetic studies revealed that arsenate adsorption on the GA was described by a pseudo-second-order kinetic equation, and the Freundlich isotherm equation fit the arsenate adsorption well (=0.994). The maximum adsorption capacity calculated by the Langmuir isotherm equation for As(Ⅴ) was 5.05 mg·g. Further studies showed that the GA operated well for As(Ⅴ) removal over a broad range in pH from 1.1 to 9.5. The coexistence of HCO and SO had no great influence on arsenic adsorption, while the HPO and SiO showed negative effects. The GA can be regenerated well, and 82% of the original adsorption capacity was maintained after three regeneration cycles.",
        "keywords": [
            "adsorption",
            "arsenic remove",
            "backwashing residuals",
            "characterization",
            "granular adsorbents"
        ],
        "authors": [
            {
                "name": "Hui-Ping Zeng",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, Colloge of Architecture and Civil Engineering, Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Sai-Sai Lü",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, Colloge of Architecture and Civil Engineering, Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Hang Yang",
                "org": "State Key Laboratory of Urban Water Resource and Environment, School of Municipal and Environmental Engineering, Harbin Institute of Technology, Harbin 150090, China."
            },
            {
                "name": "Can Yin",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, Colloge of Architecture and Civil Engineering, Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Rui-Hua Cao",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, Colloge of Architecture and Civil Engineering, Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Yan-Ju Wang",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, Colloge of Architecture and Civil Engineering, Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Dong Li",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, Colloge of Architecture and Civil Engineering, Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Jie Zhang",
                "org": "State Key Laboratory of Urban Water Resource and Environment, School of Municipal and Environmental Engineering, Harbin Institute of Technology, Harbin 150090, China."
            }
        ],
        "venue": "Huan jing ke xue= Huanjing kexue",
        "year": 2018
    },
    "og9v5eDv": {
        "id": "og9v5eDv",
        "title": "[COD Requirement for Biological Phosphorus Removal Granule System Under Different Phosphorus Concentrations].",
        "abstract": "In this study, the effect of COD loading on a biological phosphorus removal granule system under different phosphorus concentrations was investigated by changing the concentration of total phosphorus (TP) and COD in the influent. The lowest concentration of COD for good performance of the biological phosphorus removal system under different phosphorus concentrations was obtained. The results show that when the concentration of TP was 10 mg·L in the influent, the lowest concentration of COD for good performance of the biological phosphorus removal system was 175 mg·L. The concentration of TP in the effluent was below 0.5 mg·L; the particle size and SVI were 1020 μm and 36 mL·g, respectively; and the contents of PN and PS (by MLSS) were 78 mg·g and 39 mg·g, respectively. Furthermore, the PN/PS was lower and the granules had good structure and performance. When the concentration of TP was 6 mg·L in the influent, the lowest concentration of COD for good performance of the biological phosphorus removal system was 150 mg·L. The concentration of TP in the effluent was below 0.3 mg·L; the particle size and SVI were respectively 960 μm and 35 mL·g; and the contents of PN and PS were 75 mg·g and 35 mg·g, respectively. Moreover, the PN/PS was lower and the granules had good structure and performance. The removal efficiency of COD was above 83% and the concentration of COD in the effluent was below 25 mg·L throughout the operational process. Under different the influent phosphorus concentrations, the contents of PN and PS decreased, PN/PS increased, particle size decreased, SVI increased, and the structure and performance of the biological phosphorus removal granules deteriorated as the COD concentration decreased.",
        "keywords": [
            "COD concentration",
            "EPS",
            "PN/PS",
            "biological phosphorus removal granules",
            "particle size",
            "removal efficiency"
        ],
        "authors": [
            {
                "name": "Dong Li",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Mei-Zhong Cao",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Yue-Zhou Guo",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Ning Mei",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Shuai Li",
                "org": "State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin 150090, China."
            },
            {
                "name": "Jie Zhang",
                "org": "State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin 150090, China."
            }
        ],
        "venue": "Huan jing ke xue= Huanjing kexue",
        "year": 2018
    },
    "8NoxWz2H": {
        "id": "8NoxWz2H",
        "title": "[Effect of Organic Carbon Source on Start-up and Operation of the CANON Granular Sludge Process].",
        "abstract": "The effect of organic carbon on the start-up and operation of the CANON granular sludge process was investigated in two SBR reactors with different strategies:gradually increased organic carbon concentration (R1) and without organic carbon (R2). The results showed that adding 50 mg·L organic carbon accelerated the start-up of the CANON granular sludge process. R1 and R2 were started up in 23 d and 32 d, respectively. Moreover, the appropriate organic carbon enhanced the activity of AOB, AnAOB, and denitrification, increasing the ammonia removal rates and total nitrogen (TN) removal rates. The maximum ammonia removal rates and total nitrogen removal rates of R1 were 92% and 88%, respectively. The maximum ammonia removal rates and total nitrogen removal rates of R2 were 89% and 80%, respectively. Further tests showed that excessive organic carbon concentration decreased the activity of AOB and AnAOB and reduced the removal efficiency of ammonia and total nitrogen. Adding organic carbon promoted denitrification activity and increased nitrogen removal efficiency.",
        "keywords": [
            "CANON",
            "SBR",
            "granular sludge",
            "low ammonia concentration",
            "organic carbon source"
        ],
        "authors": [
            {
                "name": "Dong Li",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Yan-Ju Wang",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Yu-Feng Lü",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Rui-Hua Cao",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Shuai Li",
                "org": "State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin 150090, China."
            },
            {
                "name": "Jie Zhang",
                "org": "State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin 150090, China."
            }
        ],
        "venue": "Huan jing ke xue= Huanjing kexue",
        "year": 2018
    },
    "40Cb8CCR": {
        "id": "40Cb8CCR",
        "title": "[Lab-scale ANAMMOX Process in a Wastewater Treatment Plant].",
        "abstract": "A lab-scale, completely anaerobic ammonium oxidation (ANAMMOX) process was operated in a municipal wastewater treatment plant (WWTP). Sewage effluent treated by an A/O process and nitrification process was input as the substance to start up the up-flow ANAMMOX filter reactor. After the 109 day, the ammonia removal rate and nitrite removal rate were greater than 90% for 15 successive days and the nitrogen removal rate was higher than 70%. The ANAMMOX filter reactor successfully started up. From days 245 to 333, the reactor was running during the winter. The weight of biomass reached 12.24 mg·g, and the average nitrogen removal rate was 54.3%. Backwash was adopted at day 461, and the weight of biomass decreased to 8.01 mg·g. From days 605 to 693, the reactor was running in the winter again. The weight of biomass was 10.41 mg·g, and the average nitrogen removal rate was sustained at 69.7%. Compared with the previous winter, the weight of biomass was lighter but the total nitrogen removal loading was 23% greater. For the entire operation, the ANAMMOX rate at high temperature was stable but that at low temperature increased from 1.5 kg·(kg·d) to 3.6 kg·(kg·d). The results show:Long-term domestication at low temperature was in favor of improving treatment efficiency of ANAMMOX process in cold environment and realized ANAMMOX process operated efficiently in winter.",
        "keywords": [
            "ANAMMOX",
            "biomembrane",
            "filter",
            "low temperature",
            "sewage"
        ],
        "authors": [
            {
                "name": "Dong Li",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Shi-Xun Zhao",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Jun-An Wang",
                "org": "Technology Research and Development Center, Beijing Sander Environmental Group, Beijing 101102, China."
            },
            {
                "name": "Jin-Feng Zhu",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Hong-Wei Guan",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Jie Zhang",
                "org": "State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin 150090, China."
            }
        ],
        "venue": "Huan jing ke xue= Huanjing kexue",
        "year": 2018
    },
    "cUxwetsU": {
        "id": "cUxwetsU",
        "title": "[Effects of Different Substrate Concentrations on the Short-term Storage of ANAMMOX Bacteria].",
        "abstract": "Anaerobic ammonium oxidizing bacteria were stored under NH-N and NO-N conditions (addition ratio 1:1) at a substrate concentration of 0, 60, and 120 mg·Lat 15℃±1℃ for 15 days. The effect of different substrate concentrations on the short-term storage and recovery of anaerobic ammonia oxidation sludge was investigated. After a short period of storage, a recovery experiment was performed. The results show that the anaerobic ammonia oxidation activities in the reactors 1, 2, and 3 decrease by 41.8%, 17.4%, and 33.4%, respectively. Because of the excessive endogenous respiration and high substrate concentration, the activities of the bacteria in reactors 1 and 3 were inhibited, respectively. Therefore, the activities decreased greatly. Because the substrate concentration was relatively suitable in reactor No. 2, excessive endogenous respiration and high substrate concentration inhibition were avoided such that the activity of the bacteria species was maintained at the substrate concentration. Endogenous respiration occurred during the storage period. Subsequently, the organic matter in the three reactors was consumed. As a result, the EPS content decreased by 50.9%, 41.7%, and 23.7% and the particle size decreased by 31.6%, 16.7%, and 8.2%, respectively. This shows that endogenous respiration is maintained by the bacteria in the matrix-deficient period and the higher concentration of the substrate can to some extent delay the endogenous respiration. During the recovery period, the three reactors recover the denitrification performances after 15, 10, and 7 d respectively. This shows that the denitrification performance of the system has a faster recovery through enhanced strain activities compared with the proliferation of the strain.",
        "keywords": [
            "activity recovery",
            "anaerobic ammonium oxidation (ANAMMOX)",
            "endogenous respiration",
            "short-term storage",
            "substrate concentration"
        ],
        "authors": [
            {
                "name": "Xue-Jian Gao",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Jie Zhang",
                "org": "State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin 150090, China."
            },
            {
                "name": "Dong Li",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Zheng-Mei Cao",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Yue-Zhou Guo",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Shuai Li",
                "org": "State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin 150090, China."
            }
        ],
        "venue": "Huan jing ke xue= Huanjing kexue",
        "year": 2018
    },
    "ifYyoddh": {
        "id": "ifYyoddh",
        "title": "[Effect of Different Ratios of Anaerobic Time and Aeration Time on the Formation of Partial Nitrification Granules].",
        "abstract": "Flocculent sludge with good nitritation performance and MLSS and SVI values of 3500 mg ·L and 162 mL ·g, respectively, was inoculated in the R1, R2, and R3 groups of the same SBR reactors at room temperature (22-28℃). The effects of different anaerobic time and aeration time ratios (1:2, 1:1, and 2:1) on the formation of partial nitrification granular sludge were studied. The results showed that granules in three reactors were successfully formed at 103 d, 82 d, and 64 d. The nitrosation rate of R1, R2, and R3 were 86%, 98%, and 96%, respectively, and SVI decreased to 89, 75, and 58 mL ·g and MLSS increased to 2314, 2781, and 2946 mg ·L, respectively, at the 85 d. The larger ratio of anaerobic time and aeration time was more conducive to sludge granulation, better settling, and nitritation performance. When the anaerobic time and aeration time ratio was 1:2, the nitritation performance of the sludge decreased since the NOB could not be suppressed, and the settling performance of the sludge became better and then worse. In addition, at the larger ratio of anaerobic time and aeration time, there was more PN and PS from microbial secretion. The PN of R1, R2, and R3 was smaller at the end of the anaerobic phase compared to that of the aerobic phase in the early stage of granular formation, but were reversed in the stabilization stage. The PS of the anaerobic phase was larger than that of the aerobic stage over the entire process.",
        "keywords": [
            "EPS",
            "SBR",
            "anaerobic time and aeration time ratio",
            "nitrosation rate",
            "partial nitrification granular"
        ],
        "authors": [
            {
                "name": "Dong Li",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Yue-Zhou Guo",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Mei-Zhong Cao",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Hui-Mei Lao",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Shuai Li",
                "org": "State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin 150090, China."
            },
            {
                "name": "Jie Zhang",
                "org": "State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin 150090, China."
            }
        ],
        "venue": "Huan jing ke xue= Huanjing kexue",
        "year": 2018
    },
    "xepn97uF": {
        "id": "xepn97uF",
        "title": "[Effect of Intermediate-Setting Aeration on the CANON Granular Sludge Process in the AUSB Reactor].",
        "abstract": "The impact of different aeration positions on startup and operation of the continuous flow CANON granular sludge process was considered by inoculating flocculent ANAMMOX activated sludge at room temperature (25±1)℃ in two sets of AUSB reactors. The aeration unit of R1 was installed 0.3 m above the base, while the aeration unit of R2 was set at the bottom. R1 and R2 successfully developed the granule CANON process on the 43rd d and 56th d, respectively. The mean particle diameter of R1 granular sludge increased to 214.79 μm, and the eigenvalue (△NO-N/△TN) was maintained at 0.128; whereas, the granular sludge size of R2 rose to 205.27 μm with an eigenvalue maintained at 0.129. The nitrogen loading rate (NLR) was gradually increased in the low ammonia-nitrogen (90 mg·L) wastewater within R1 and R2. This was more beneficial in R1, resulting in the persistent growth of CANON granular sludge and the enhancement of the systematic nitrogen removal rate (NRR). The average particle diameter of R1 rose to 507.46 μm in 88 d, while NRR reached up to 0.277 kg·(m·d). R2 granule sludge particle size was 467.72 μm after 108 d of cultivation, and achieved a 0.243 kg·(m·d)NRR, which was 87.73% of that in R1. During the course of steady operation, the specific anoxic/aerobic mode of R1 effectively suppressed NOB microbial activity, the eigenvalue remained around 0.127±0.003, and the NRR of R1 was maintained at about (0.262±0.019) kg·(m·d). However, NOB was propagated observably in the continuously aerobic R2, whose eigenvalue rose to 0.136±0.004, while NRR was merely (0.231±0.015) kg·(m·d) after 125 d of long-term operation. During the whole experiment period, the intermediate-setting aerated AUSB accelerated the formation of CANON granular sludge evolving from flocculent ANAMMOX sludge, and better nitrogen removal performance and operational stability were achieved.",
        "keywords": [
            "AUSB",
            "bottom-setting aeration",
            "granular sludge",
            "intermediate-setting aeration",
            "operational stability"
        ],
        "authors": [
            {
                "name": "Shuo Cheng",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, College of Architecture and Civil Engineering, Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Dong Li",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, College of Architecture and Civil Engineering, Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Jie Zhang",
                "org": "State Key Laboratory of Urban Water Resource and Environment, School of Municipal and Environmental Engineering, Harbin Institute of Technology, Harbin 150090, China."
            },
            {
                "name": "Shuai Li",
                "org": "State Key Laboratory of Urban Water Resource and Environment, School of Municipal and Environmental Engineering, Harbin Institute of Technology, Harbin 150090, China."
            },
            {
                "name": "Rui-Hua Cao",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, College of Architecture and Civil Engineering, Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Sai-Sai Lü",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, College of Architecture and Civil Engineering, Beijing University of Technology, Beijing 100124, China."
            }
        ],
        "venue": "Huan jing ke xue= Huanjing kexue",
        "year": 2018
    },
    "HMrxyCV6": {
        "id": "HMrxyCV6",
        "title": "Start-Up of a Biofilter in a Full-Scale Groundwater Treatment Plant for Iron and Manganese Removal.",
        "abstract": "In recent years, biological purification technology has been widely developed in the process of iron and manganese removal from groundwater. The cultivation and maturation of the biological filter layer are key for biological iron and manganese removal processes. The time needed for maturation varies significantly with the water quality, filter and filter media conditions and operation parameters; sometimes it takes only one or two months, sometime more than half a year. In this paper, the feasibility of adopting an intermittent operation for the cultivation of biofilter was investigated with productive filters in a groundwater treatment plant, and the comparative test of the filter column was conducted. The results showed that the intermittent operation had little effect on the cultivation of the biofilter because dissolved oxygen would be gradually exhausted during the filter-suspension process, making the filter layer anaerobic, thus possibly inhibiting the growth and reproduction of IMOB (Iron and Manganese Oxidizing Bacteria). At the same time, the test shows that when the mature biological filter needs the suspension operation, the emptying method should be considered to avoid the destruction of the biological layer.",
        "keywords": [
            "biofilter",
            "groundwater",
            "iron and manganese removal"
        ],
        "authors": [
            {
                "name": "Huiping Zeng",
                "org": "Key Laboratory of Water Science and Water Environment Recovery Engineering, Beijing University of Technology, Beijing 100124, China. zenghuiping@bjut.edu.cn."
            },
            {
                "name": "Can Yin",
                "org": "Key Laboratory of Water Science and Water Environment Recovery Engineering, Beijing University of Technology, Beijing 100124, China. 18811715867@163.com."
            },
            {
                "name": "Jie Zhang",
                "org": "State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin 150090, China. 6282031@163.com."
            },
            {
                "name": "Dong Li",
                "org": "Key Laboratory of Water Science and Water Environment Recovery Engineering, Beijing University of Technology, Beijing 100124, China. lidong2006@bjut.edu.cn."
            }
        ],
        "venue": "International journal of environmental research and public health",
        "year": 2019
    },
    "KIfGKT9S": {
        "id": "KIfGKT9S",
        "title": "[Startup and Stabilization of Nitrosation in an Anoxic-aerobic Continuous-flow Reactor with Granules].",
        "abstract": "Matured nitrosation granules were inoculated to an anoxic-aerobic continuous-flow reactor at room temperature (17-19℃). The startup and stabilization of nitrosation with granules were studied. The results show that the nitrosation of the continuous-flow was successfully achieved with an average nitrite accumulation rate (NAR) above 95%. With the increase of the dissolved oxygen (DO) content from (3±0.2) to (4.5±0.2) mg·L in the aerobic zone, the NAR remained above 95%. The effect of the hydraulic retention time (HRT) of the continuous-flow reactor was investigated. The short HRT (8.4 h) sped up the circulation of the sludge particles in the continuous-flow system such that the broken granular sludge could not be integrated in time, resulting in the deterioration of granular sludge settling and the loss of sludge granules. The performance of the system was restored with the increase of the HRT to 12.2 h and the continuous-flow system stabilized. The ammonia removal efficiency and NAR were 86.7% and 96.2% on day 166, respectively.",
        "keywords": [
            "anoxic-aerobic",
            "dissolved oxygen (DO)",
            "hydraulic retention time (HRT)",
            "nitrite accumulation rate (NAR)",
            "nitrosation granules"
        ],
        "authors": [
            {
                "name": "Dong Li",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Yue-Zhou Guo",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Hui-Mei Lao",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Mei-Zhong Cao",
                "org": "Key Laboratory of Beijing for Water Quality Science and Water Environment Recovery Engineering, Beijing University of Technology, Beijing 100124, China."
            },
            {
                "name": "Jie Zhang",
                "org": "State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin 150090, China."
            }
        ],
        "venue": "Huan jing ke xue= Huanjing kexue",
        "year": 2019
    },
    "H7xSsMmn": {
        "id": "H7xSsMmn",
        "title": "Evaluation of municipal sewage treatment systems for pollutant removal efficiency by measuring levels of micropollutants.",
        "abstract": "In order to evaluate the municipal sewage treatment systems used at Harbin municipal sewage treatment plant for their pollutant removal efficiency, raw sewage and effluent samples at different treatment stages from the sewage treatment systems were taken, priority pollutants (PPs) were identified and quantified using gas chromatography-mass spectrometry (GC-MS) and inductively coupled plasma-atomic emission spectrograph (ICP-AES). The test results indicated that there were one hundred and fifty species of organic pollutants identified in the raw sewage sample, and only ten species of PPs in all the sewage samples. The levels of dimethyl phthalate (DMP), diethyl phthalate (DEP), dibutyl phthalate (DBP), di-n-octyl phthalate (DnOP) in the sewage samples were 0.779-0.111 microg l(-1), 1.977-0.022 microg l(-1), 6.411-2.194 microg l(-1) and 7.152-2.953microg l(-1), respectively, and most of these phthalate esters (PAEs) were removed through anaerobic/aerobic (A/O) process; The levels of alachlor, acetochlor, atrazine were 0.074-0.021 microg l(-1), 0.160-0.096 microg l(-1) and 0.238-0.184 microg l(-1), respectively, and the total removal efficiency of atrazine was poorest through the sewage treatment systems. The levels of Cu, Cr, Se, Hg, Ni and Zn were 0.0030-0.2327 mg l(-1). It is therefore concluded from these results that the sewage treatment systems were efficient in removing most of the organic and inorganic compounds in this study, and so, the discharged effluent could cause little of the secondary pollution of the aquatic environment.",
        "keywords": [
            "gc-ms",
            "icp-aes",
            "levels of pps",
            "sewage treatment systems"
        ],
        "authors": [
            {
                "name": "Xiang-Ji Kong",
                "org": ""
            },
            {
                "name": "Dong Li",
                "org": "Laboratory of Water Quality Science and Recovery of Aquatic Environment, Beijing University of Technology, Beijing 100022, China"
            },
            {
                "name": "Lian-Qiu Cao",
                "org": "School of Municipal and Environmental Engineering, Harbin Institute of Technology, Harbin 150090, China"
            },
            {
                "name": "Xue-Mei Zhang",
                "org": "Heilongjiang Provincial Institute of Measurement and Verification, Harbin 150036, China"
            },
            {
                "name": "Yan Zhao",
                "org": "School of Municipal and Environmental Engineering, Harbin Institute of Technology, Harbin 150090, China"
            },
            {
                "name": "Yang Lv",
                "org": "School of Municipal and Environmental Engineering, Harbin Institute of Technology, Harbin 150090, China"
            },
            {
                "name": "Jie Zhang",
                "org": "Laboratory of Water Quality Science and Recovery of Aquatic Environment, Beijing University of Technology, Beijing 100022, China"
            }
        ],
        "venue": "Chemosphere",
        "year": 2008
    },
    "aWlfmUYv": {
        "id": "aWlfmUYv",
        "title": "Research on CANON process for municipal sewage in room temperature",
        "abstract": "In the room temperature 14.7-24.7 degrees C, simultaneous nitrification-ANAMMOX (CANON) process for municipal sewage was tested by SBR while the DO was controlled between 0.05 and 0.30 mg/L. As a result, the research shows that CANON process can be applied to the nitrogen treatment of municipal wastewater in room temperature by SBR. DO can be regarded as the indication parameter of reaction terminal, and 1 mg/L has been confirmed in the experiment. In the exploring SBR experiments, the consumption velocity of NH4(+) -N was 0.164-0.218 kg/(m3 x d), the production velocity of NO3(-) -N was 0.026-0.036 kg/(m3 x d), the removal velocity and efficiency of TN were 0.124-0.194 kg/(m3 x d) and 65%-75% respectively. Additionally, in the improving SBR experiments, there were three methods for avoiding nitrite accumulation and increasing the nitrogen removal efficiency. They were improving temperature, adding non-aeration period of time and increasing the quantity of ANAMMOX bacteria. Therefore, the removal efficiency of TN was increased to 77%-88% through the three ways above. However, in view of the nitrogen removal velocity and the fact of engineering application condition, the third approach was the best to advance the general ability of ANAMMOX.",
        "keywords": [
            "ANAMMOX",
            "Municipal sewage",
            "Nitrification",
            "Room temperature"
        ],
        "authors": [
            {
                "name": "Jun-An Wang",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "Dong Li",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "Zhi-Yong Tian",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "Zhao-Liang Zhu",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "Kun-Ming Fu",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            }
        ],
        "venue": "Huan jing ke xue= Huanjing kexue / [bian ji, Zhongguo ke xue yuan huan jing ke xue wei yuan hui \"Huan jing ke xue\" bian ji wei yuan hui.]",
        "year": 2009
    },
    "QDsJYG17": {
        "id": "QDsJYG17",
        "title": "Start-up and nitrogen removal performance of anaerobic ammonium oxidation bio-filter",
        "abstract": "The study on the start-up and the performance of ANAMMOX process was undertaken by using the filter reactor loading ceramsite media. In this study, the effluent of \"A-O\" phosphorus removal process was feeded into the reactor as experimental substrate. Firstly, the aerobic nitrifying bio-membrane on the ceramsite media of reactor was cultivated naturally; then the nitrifying bio-membrane was converted into the ANAMMOX bio-membrane by the natural selection and artificial inducement under the anoxic condition. It had been 7 months before the ANAMMOX bio-filter was started up successfully, in which the removal load of TN reached 6.8 kg/m3·d with an apparent specific growth rate of the ANAMMOX biomass upto 0.0018 h-1. The upflow experiment indicates that the upflow operation is favorable to improving nitrogen removal capability of the ANAMMOX bio-filter. The maximum total nitrogen removal load of the experimental filter reached 12.37 kg/m3·d, which was higher than the maximum value of 8.9 kg/m3·d that were achieved in a gas lift reactor reported in the literature. In addition, the stoichiometry and the removal property of COD in the process of ANAMMOX indicates that the heterotrophic denitrification process follows the ANAMMOX process and is favorable to the total nitrogen removal of the bio-filter.",
        "keywords": [
            "ANAMMOX",
            "Bio-filter",
            "Nitrogen removal",
            "Starting-up",
            "Upflow",
            "Wastewater treatment"
        ],
        "authors": [
            {
                "name": "TIAN Zhi-yong",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "Dong Li",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "Hong Yang",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "ZHANG Li-cheng",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "ZHANG Shu-de",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            }
        ],
        "venue": "Beijing Gongye Daxue Xuebao / Journal of Beijing University of Technology",
        "year": 2009
    },
    "i6XZYOFZ": {
        "id": "i6XZYOFZ",
        "title": "Optimization theory and system design of integrated reclamation flow for municipal sewage",
        "abstract": "A new optimization theory of integrated reclamation flow for municipal sewage is put forward. In addition, the mechanism and representative technics of biological dephosphorization and nitrogen removal are expatiated. Based on the new technics of biological dephosphorization and nitrogen removal, some systems of wastewater integrated reclamation flow are formed according to the optimization theory.",
        "keywords": [
            "Dephosphorization and nitrogen removal",
            "Integrated flow optimization",
            "Municipal sewage",
            "Reclamation"
        ],
        "authors": [
            {
                "name": "WANG Jun-an",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "Dong Li",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            }
        ],
        "venue": "Xiandai Huagong/Modern Chemical Industry",
        "year": 2009
    },
    "7ucBLQBz": {
        "id": "7ucBLQBz",
        "title": "Relations of the substrate concentration to the COD and pH in the ANAMMOX process",
        "abstract": "Analyzed the change rules of the concentration of nitrogen compounds, COD and pH in the upflow ANAMMOX biofilter, and the distribution rules of the ANAMMOX activity and biomass. And furthermore, the relations of the nitrogen compounds concentration to the COD and pH in the ANAMMOX process were studied with the statistical method. The results showed that the dissolved oxygen and nitrogen load together caused the uneven distribution of the ANAMMOX activity and biomass along the filter layer in a \"ridge\" shape; the existence of heterotrophic denitrification and the consumption of H+ made the COD decrease and the pH increase in the ANAMMOX process; the concentration of the organic matters below 100 mg/L has little influence on ANAMMOX bacteria, and the relations of the substrate NH4 +-N concentration to the COD and pH showed a good linear correlation. The slopes of the fitting line of the COD-NH4 +-N and pH-NH4 +-N were 1.1138±0.0522 and-0.1113±0.0012 respectively, with the confidence level being 95% and the average correlation coefficient R2 0.9823 and 0.9850 respectively.",
        "keywords": [
            "ANAMMOX",
            "Bio-filter",
            "COD",
            "pH",
            "Substrate concentration",
            "Up-flow"
        ],
        "authors": [
            {
                "name": "Zhiyong Tian",
                "org": "Chinese Research Academy of Environmental Sciences(Chinese Research Academy of Environmental Sciences,Chinese Research Academy of Environmental Science),Beijing,China"
            },
            {
                "name": "Dong Li",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            }
        ],
        "venue": "Huanjing Kexue/Environmental Science",
        "year": 2009
    },
    "WIm9oaJ2": {
        "id": "WIm9oaJ2",
        "title": "Nitrite effect on biological phosphorus removal process",
        "abstract": "In this study, phosphorus accumulating organisms (PAOs) were cultivated in two SBR systems, one operated as anaerobic/aerobic mode, the other as anaerobic/anoxic mode. The effects of nitrite on the two modes of phosphorus removal system were investigated. The results showed that presence of nitrite inhibits both aerobic and anoxic phosphorus uptake, but aerobic phosphorus uptake was more affected than anoxic phosphorus uptake. In this research, 0.88 mg/gVSS and 6.72 mg/gVSS were observed as threshold for aerobic and anoxic phosphate uptake, respectively. With the aid of a stepwise elevation of NO2 --N added in influent, denitrifying phosphorus accumulating organisms were gradually accommodated to resist and utilize NO2 --N as electron acceptor, but the phosphorus removal efficiency was lower than O2 and NO3 --N as electron acceptors.",
        "keywords": [
            "Biological phosphorus removal",
            "Electron acceptor",
            "Nitrite inhibition",
            "Phosphorus accumulating organisms"
        ],
        "authors": [
            {
                "name": "BAO Lin-lin",
                "org": "Harbin Institute of Technology(Harbin Institute of Technology,Harbin Inst. of Technol.),Harbin,China"
            },
            {
                "name": "LI Xiang-kun",
                "org": "Harbin Institute of Technology(Harbin Institute of Technology,Harbin Inst. of Technol.),Harbin,China"
            },
            {
                "name": "Dong Li",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "KONG Xiang-ji",
                "org": "Harbin Institute of Technology(Harbin Institute of Technology,Harbin Inst. of Technol.),Harbin,China"
            },
            {
                "name": "Yan Zhao",
                "org": "Harbin Institute of Technology(Harbin Institute of Technology,Harbin Inst. of Technol.),Harbin,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            }
        ],
        "venue": "Harbin Gongye Daxue Xuebao/Journal of Harbin Institute of Technology",
        "year": 2010
    },
    "jM3z3N0k": {
        "id": "jM3z3N0k",
        "title": "Research on bulking sludge and system recovery of anaerobic-aerobic process",
        "abstract": "Under the condition of low temperature, after the state of activated bulking sludge observed, the problem of sludge bulking is solved through adjusting the running parameters of anaerobic-oxic reactor. Furthermore, the recovery approaches and steady and long-time running under the condition of room temperature are discussed. The result shows that the bulking sludge under the condition of low temperature has both the characteristics of filamentous bulking and non-filamentous bulking at the same time. The system's recovery time under the condition of room temperature is 5 days shorter than that under the lower temperature. The aerobic sludge is much easier than the anaerobic sludge for the system recovery, and the more of sludge the easier. Because of the effect of different seasons, the running parameters of the reactor should be adjusted in time along with the water temperature.",
        "keywords": [
            "Biological phosphorus removal",
            "Filamentous bacteria",
            "Low temperature",
            "Municipal wastewater",
            "Sludge bulking"
        ],
        "authors": [
            {
                "name": "WANG Jun-an",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "Dong Li",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "TAO Xiao-xiao",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "Zhan Li",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            }
        ],
        "venue": "Xiandai Huagong/Modern Chemical Industry",
        "year": 2010
    },
    "iEBXYESL": {
        "id": "iEBXYESL",
        "title": "The monitoring and removal efficiency of toxic and harmful organic matter in northern wastewater treatment plant",
        "abstract": "In recent years, large amount of plastics have caused a wide distribution in the world. The thesis focuses on this challenge and tries to investigate the transportation, transference and degradation rules of toxic and harmful organic matter in two wastewater treatment plants (WWTP) at Harbin by using liquid-liquid extraction (LLE) and solid phase extraction (SPE). Choosing environment hormone-phthalate acid esters (PAEs) as research objects, the presence, transportation and degradation of PAEs are investigated in secondary and advanced treatment process. This research indicate that most organic pollutants can be removed by secondary treatment plant, the removal ratio of trace organic pollutant is 79%-94% for Taiping WWTP, 88%-90% of removal ratio for Wenchang WWTP. The organic species numbers detected in the two WWTP are 73 and 70 by means of LLE, 87 and 101 by means of SPE, respectively. The total numbers of organic pollutants detected in this study are 102, among which 12 species are belong to Stress control pollutants in water environment by USEPA and 6 species belong to China priority controlled pollutant in black lists. Most pollutants in effluent are PAEs.",
        "keywords": [
            "Environmental hormone",
            "Toxic and harmful organic matter",
            "Wastewater treatment plant"
        ],
        "authors": [
            {
                "name": "HUANG Rong-xin",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "Dong Li",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "PENG Yong-zhen",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "CHEN Jian-yu",
                "org": "State Environmental Protection Administration(State Environmental Protection Administration,State Environmental Protection Administration of China),Beijing,China"
            }
        ],
        "venue": "Beijing Gongye Daxue Xuebao/Journal of Beijing University of Technology",
        "year": 2011
    },
    "ZAApvoqM": {
        "id": "ZAApvoqM",
        "title": "Quick start-up for ANAMMOX biofilter under the condition of low ammonium",
        "abstract": "In the condition of room temperature 14.2~23.9°C, ANAMMOX bacteria granule sludge is inoculated to the biofilter, which is filled with lava as carrier. In the inlet sewage of initial stages, ρ(NH4 +-N)=70 mg/L, ρ(NO2 --N)=90 mg/L, the removal load of TN is 0.12 kg/(m3·d). After 105 days, the removal load of TN increases to 2.22 kg/(m3·d). The quick start-up of ANAMMOX biofilter was realized successfully. In the start-up process, according to the change of N2 yield, apparent color of biofilm, nitrogen removal velocity and pH value, the whole start-up process can be divided into two phases including domestication and quick multiplication of ANAMMOX bacteria.",
        "keywords": [
            "ANAMMOX",
            "Bio-film reactor",
            "Municipal wastewater",
            "Quick start-up",
            "Room temperature"
        ],
        "authors": [
            {
                "name": "WANG Jun-an",
                "org": "Technology R and D Center(Technology R and D Center),Beijing,China"
            },
            {
                "name": "Dong Li",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            }
        ],
        "venue": "Beijing Gongye Daxue Xuebao/Journal of Beijing University of Technology",
        "year": 2011
    },
    "eIH0b26k": {
        "id": "eIH0b26k",
        "title": "Coupling nitrogen removal bacteria based on the ANAMMOX process",
        "abstract": "Two SBRs are first used to train activated sludge of heterotrophic denitrification bacteria for nitrate and nitrite, respectively. Then, the activated sludge that has ANAMMOX function is simultaneously inoculated into the two reactors. The efficiency of the coupling activated sludge including heterotrophic denitrification bacteria and ANAMMOX bacteria is researched. Experimental results show that the efficiency of heterotrophic denitrification of nitrite is better than that of nitrate. However, the coupling effect with ANAMMOX bacteria is on the contrary. Under the condition of aeration, the two reactors have better nitrification function at the same time, and the accumulation ratios of nitrite are 62.2% and 87.3%, respectively.",
        "keywords": [
            "ANAMMOX",
            "Biological nitrogen removal",
            "Heterotrophic denitrification",
            "Shortcut nitrification"
        ],
        "authors": [
            {
                "name": "WANG Jun-an",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "Dong Li",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "TAO Xiao-xiao",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            },
            {
                "name": "Zhan Li",
                "org": "Beijing University of Technology(Beijing University of Technology,Beijing Polytechnic University),Beijing,China"
            }
        ],
        "venue": "Beijing Gongye Daxue Xuebao/Journal of Beijing University of Technology",
        "year": 2012
    },
    "oU0Xmblr": {
        "id": "oU0Xmblr",
        "title": "Structural analysis of the photonic switching network in three divisions using diagrams",
        "abstract": "A new method using connection logical maps to describe the alteration of network structure from the space-division switching network to the photonic switching network in three divisions was proposed. As an example, a multistage photonic switching network with 8 input ports and 8 output ports in the space-only division, which matches Benes structure, is converted to another network in three divisions with the same connection structure by this method.",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Guorui Li",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Daxiong Xu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Zhongguo Jiguang/Chinese Journal of Lasers",
        "year": 1998
    },
    "txbMHR51": {
        "id": "txbMHR51",
        "title": "Functional architectures for optical cross-connect nodes",
        "abstract": "Optical cross-connects (OXC′s) will be key switching and routing components in future wavelength-division multiplexed optical transport networks. The physical architecture for one OXC node has been deeply studied nowadays. Several schemes to build the OXC using variant photonic devices has already been proposed. In terms of the optical cross-connect function a new model to describe the functional architecture for the OXC node is given in this paper and the comparison for the functional architectures among different OXC designs is also made.",
        "keywords": [
            "Optical cross-connect",
            "Optical transport network",
            "Wavelength-division multiplexing"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Yunfeng Shen",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Guorui Li",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Daxiong Xu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Guangzi Xuebao/Acta Photonica Sinica",
        "year": 1998
    },
    "lS1lbgIb": {
        "id": "lS1lbgIb",
        "title": "Five-node optical wavelength division multiplexing experimental network in China",
        "abstract": "A five-node, eight-channel, wave-length division multiplexing (WDM) experimental all-optical network is present in China. The network has nodes of three OADMs and two OXCs, management function and self-healing function. Digital signal of 2.5 Gbit/s and analogue signals of CATV can be transmitted through and cross-connected. BER is less than 1.5 × 10-13 with digital signal of 2.5 Gbit/s through four of EDFAs and fiber of 143.2 km.",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Anshi Xu",
                "org": "Peking University(Peking University),Beijing,China"
            },
            {
                "name": "Hanyi Zhang",
                "org": "Tsinghua University(Tsinghua University,Tsinghua Univ,Tsinghua Univ.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Deming Wu",
                "org": "Peking University(Peking University),Beijing,China"
            },
            {
                "name": "Yili Guo",
                "org": "Tsinghua University(Tsinghua University,Tsinghua Univ,Tsinghua Univ.),Beijing,China"
            },
            {
                "name": "Bingkun Zhou",
                "org": "Tsinghua University(Tsinghua University,Tsinghua Univ,Tsinghua Univ.),Beijing,China"
            },
            {
                "name": "Zhenning Tao",
                "org": "Peking University(Peking University),Beijing,China"
            },
            {
                "name": "Wenlu Chen",
                "org": "Tsinghua University(Tsinghua University,Tsinghua Univ,Tsinghua Univ.),Beijing,China"
            },
            {
                "name": "Yunfeng Shen",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "ZhangYuan Chen",
                "org": "Peking University(Peking University),Beijing,China"
            },
            {
                "name": "Lei Zong",
                "org": "Tsinghua University(Tsinghua University,Tsinghua Univ,Tsinghua Univ.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Ying Tang",
                "org": "Peking University(Peking University),Beijing,China"
            },
            {
                "name": "Yunsi Fei",
                "org": "Tsinghua University(Tsinghua University,Tsinghua Univ,Tsinghua Univ.),Beijing,China"
            },
            {
                "name": "Xuesong Wei",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Baicheng Zhang",
                "org": "Peking University(Peking University),Beijing,China"
            },
            {
                "name": "Zhigen Xu",
                "org": "Tsinghua University(Tsinghua University,Tsinghua Univ,Tsinghua Univ.),Beijing,China"
            },
            {
                "name": "Xueyuan Liu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Hongbo Wang",
                "org": "Peking University(Peking University),Beijing,China"
            },
            {
                "name": "Jian Sun",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Gang Zhao",
                "org": "Peking University(Peking University),Beijing,China"
            },
            {
                "name": "Xiaodong Zhao",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Maohai Zhao",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Chinese Journal of Electronics",
        "year": 1999
    },
    "jDdOvEMV": {
        "id": "jDdOvEMV",
        "title": "Algorithm for computing the average hop distance of reduced-stage shuffle networks",
        "abstract": "GSA is a generalization of shuffle-exchange networks and it can represent a family of networks structures (including ShuffleNet and de Bruijn graph) for an arbitrary number of nodes. GSN employs a regular interconnection graph with highly desirable properties and it can serve as a logical (virtual), multihop topology for constructing the next generation of light wave networks using wavelength-division multiplexing (WDM). GSN can be divided into two classes: extra-stage and reduced-stage. The architecture of the GSN was introduced briefly. Then, the performance of the GSN was analyzed. An algorithm for computing the average hop distance for the reduced-stage GSN was proposed.",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Yunfeng Shen",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Guorui Li",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Daxiong Xu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Zhongguo Jiguang/Chinese Journal of Lasers",
        "year": 1999
    },
    "7jSHaHeP": {
        "id": "7jSHaHeP",
        "title": "Research on same-frequency crosstalk in all-optical network",
        "abstract": "Same-frequency crosstalk will degrade the system performance seriously in all-optical networks. The impact of same-frequency crosstalk on intensity-modulation direct-detection system is studied both theoretically and experimentally. The relationships between the impact and various factors are discussed. Instructions are provided for the design of all-optical networks.",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Yuanfeng Shen",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Huajie He",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Tien Tzu Hsueh Pao/Acta Electronica Sinica",
        "year": 1999
    },
    "HjwroLSP": {
        "id": "HjwroLSP",
        "title": "New algorithm of wavelength assignment in wavelength-routed optical networks",
        "abstract": "The assignment of wavelength in the design of optical path layer of wavelength-routed network is discussed and a new mathematical description is proposed. According to the characteristics of the wavelength-routed optical network and the concept of pathgraph, a new algorithm for wavelength assignment is proposed. The assignment of wavelength is resulted from the resolve of the vertices coloring problem of the pathgraph. Simulation on computer is carried out to compare this algorithm with a used one on random network, the higher wavelength efficiency is acquired by new algorithm. This algorithm can be used to exploit the wavelength resources effectively under the condition of static services.",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Xuesong Wei",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Guorui Li",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Beijing Youdian Xueyuan Xuebao/Journal of Beijing University of Posts And Telecommunications",
        "year": 1999
    },
    "8AcS1SdQ": {
        "id": "8AcS1SdQ",
        "title": "Scaling limitation of full-mesh rings using the novel OADMs",
        "abstract": "",
        "keywords": [
            "wavelength division multiplexing",
            "crosstalk",
            "oadm",
            "network topology",
            "scaling limit",
            "optical switches",
            "scaling"
        ],
        "authors": [
            {
                "name": "laih fang",
                "org": "peking university"
            },
            {
                "name": "xueyuan liu",
                "org": ""
            },
            {
                "name": "jianquan wang",
                "org": ""
            },
            {
                "name": "mianfeng lin",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "wanyi gu",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2000
    },
    "riLFRpYN": {
        "id": "riLFRpYN",
        "title": "The research and realization of OADM technology in metro optical network",
        "abstract": "Optical Add/Drop Multiplexer (OADM) is an important network element. In the ring architecture, OADM can be introduced to make efficient use of network capacity, network protection, wavelength routing and many more good features. In this paper, an OADM with high performance realized by us is demonstrated. The key technical problem, solving method and design rule for the OADM are given. The experiment results of long distance transmission by use of the OADM are illuminated by some figure. It shows that the OADM realized by us is advanced, practical, reliable, and applied in China Advanced Info-Optical Network (CAINONet).",
        "keywords": [
            "Optical add/drop multiplexer",
            "Optical communication",
            "WDM"
        ],
        "authors": [
            {
                "name": "Yuefeng Ji",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Yongmei Sun",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Bin Ye",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Yong Zhao",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Proceedings of SPIE - The International Society for Optical Engineering",
        "year": 2001
    },
    "A2Tmkrfi": {
        "id": "A2Tmkrfi",
        "title": "Atomic components for WDM simulation software",
        "abstract": "The atomic component is introduced based on atomic functional model. The method to build optical network elements model using atomic components is proposed. Atomic components necessary to build the key network elements (i.e. OADM/OXC) are given, the results are presented also. The application of atomic components is demonstrated in simulation software of optical transport network.",
        "keywords": [
            "Atomic functional model",
            "OADM",
            "Optical network",
            "OXC",
            "WDM"
        ],
        "authors": [
            {
                "name": "Xiaofei Cheng",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Mianfeng Lin",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Tien Tzu Hsueh Pao/Acta Electronica Sinica",
        "year": 2001
    },
    "2ID1Hhip": {
        "id": "2ID1Hhip",
        "title": "Two modules for building OADM and OXC in metro networks",
        "abstract": "One FBG-MZI-based component and one mediator are proposed in this paper. The proposed OADM building module consists of one FBG-based MZI module and one reconfigurable module, and it can add/drop or pass-by the specified wavelength. OADM created by concatenating the proposed modules, owns wavelength modularity, and can add-drop and pass-by any specified wavelengths. The mediator is one simplified 4 × 4 optical switch matrix. It can be used to interconnect multiple OADM modules to build one OXC with multiple ports.",
        "keywords": [
            "fiber bragg grating (fbg)",
            "mach-zender interferometer (mzi)",
            "metro optical network",
            "modularity",
            "matrices",
            "networks",
            "optical switch",
            "optical switching",
            "fiber bragg gratings"
        ],
        "authors": [
            {
                "name": "Mianfeng Lin",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wenjian Wu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Laifu Fang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Proceedings of SPIE - The International Society for Optical Engineering",
        "year": 2001
    },
    "r3O0a4sY": {
        "id": "r3O0a4sY",
        "title": "The IP-based restoration algorithm for optical networks",
        "abstract": "One distributed restoration algorithm used to protect optical transport networks against network failures is proposed in the paper. The algorithm takes advantage of the existing IP protocols, and therefore it can restore the affected traffic in the distributed and efficiently manner. By carrying the wavelength availability information in protocol data unit, the algorithm can reserve the required capacities as well as search the restoration routing.",
        "keywords": [
            "IP protocol",
            "Optical transport networks",
            "Provisioning",
            "The distributed restoration algorithm"
        ],
        "authors": [
            {
                "name": "Mianfeng Lin",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Chunbo Mu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Laifu Fang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Proceedings of SPIE - The International Society for Optical Engineering",
        "year": 2001
    },
    "BVp4Cqmx": {
        "id": "BVp4Cqmx",
        "title": "Novel scheme for routing optical supervisory channels adhering to OXC",
        "abstract": "One novel scheme for routing optical supervisory channels adhering to optical cross-connect (OXC) is developed in this paper. Beginning with the definition of the new frame to carry the optical channel (OCH) layer overheads, the proposed scheme processes the overhead associated the individual optical channel, which is carried by optical supervisory channel (OSC), in the similar way as the message-oriented data communication channel (DCC) in OSC. Therefore, all OCH-specified information carried by OSC can be routed by a uniform manner.",
        "keywords": [
            "optical channel",
            "optical cross connect",
            "optical supervisory channel (osc)",
            "overhead"
        ],
        "authors": [
            {
                "name": "Mianfeng Lin",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jianwu He",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Laifu Fang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Proceedings of SPIE - The International Society for Optical Engineering",
        "year": 2001
    },
    "0FMIVqAP": {
        "id": "0FMIVqAP",
        "title": "Novel architecture model and information model for OTN",
        "abstract": "The development of complicated networking nodes (such as OXC and OADM) and the requirements of flexible configuration as well as protection and restoration functions of the next generation optical networks challenge the current functional architecture model defined in G.805. Based on the analysis of the current solutions, we propose to open the stiff binding relationships of the transport processing functions and transport entities specified in G.803. Virtual layer network, virtual CI, virtual adaptation, virtual connection point and virtual link connection are introduced as an extension of the current functional components to model the architecture of optical transport networks (OTN) in order to supply different transparent connections within a layer network. Corresponding managed object classes and the guidelines of using the virtual components to build the management information model of OTN are defined.",
        "keywords": [
            "Characteristic information (CI)",
            "Connection",
            "Information model",
            "Layer network",
            "Managed object class",
            "Optical channel (OCh)",
            "Optical transport network (OTN)"
        ],
        "authors": [
            {
                "name": "Han Li",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "YueYing Hu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "JianQuan Wang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Proceeding of the International Conference on Telecommunications",
        "year": 2002
    },
    "VdIBqz2g": {
        "id": "VdIBqz2g",
        "title": "Survivability of the optical networks consisting of the two-level cross-connect node",
        "abstract": "The protection designing issue for the optical network consisting of the two-level optical crass-connect node is investigated. The protection capacities programming model is built and simulated. The simulation result shows that the protection performance severely depends on the optimization function of the model and the assignment policy of network capacities.",
        "keywords": [
            "Multiple granularities cross-connect",
            "Optical network",
            "Protection performance",
            "Protection programming model"
        ],
        "authors": [
            {
                "name": "Mianfeng Lin",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Laifu Fang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jianwu He",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Tien Tzu Hsueh Pao/Acta Electronica Sinica",
        "year": 2002
    },
    "7Fazm7Wr": {
        "id": "7Fazm7Wr",
        "title": "Spare capacity allocation in optical networks",
        "abstract": "With the emergence of optical cross-connects (OXCs) and optical add/drop multiplexers (OADMs), all-optical networks and a new layer named as optical layer are emerging. Although the number of available wavelength per fiber and the bandwidth per wavelength are all becoming larger, the total bandwidth per fiber is limited. So for a network operator, pre-allocating minimum spare capacity in an optical network under the advanced connection demands to meet to survivability requirements is needed. In this paper, the above problem can be formulized as an ILP model, in which different survivability requirements of connections are considered jointly. The solution to this problem has an advantage over the result of the separate allocation problem, i.e., allocating resources for service connections and protection/restoration connections are performed separately.",
        "keywords": [
            "ilp",
            "network planning",
            "optical networks",
            "spare resource allocation",
            "survivability",
            "networks",
            "optical cross connect",
            "optical add drop multiplexer"
        ],
        "authors": [
            {
                "name": "Jianwu He",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wenyan Jin",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Mianfeng Lin",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Proceedings of SPIE - The International Society for Optical Engineering",
        "year": 2002
    },
    "daVvuajU": {
        "id": "daVvuajU",
        "title": "One lower limit protection time model for optical transport networks",
        "abstract": "Based on the analysis on protection process protecting optical transport network in the condition of failure, one lower limit model for evaluating the protection and switching time is shown and validated. The emulation result shows that the protection time severely depends on protection and switching protocol, and the effect of the switch time of optical switches on protection time is independent on network size.",
        "keywords": [
            "Optical transport network",
            "Protection and switch",
            "Protection time"
        ],
        "authors": [
            {
                "name": "Mianfeng Lin",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Laifu Fang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Xiaofei Cheng",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Tien Tzu Hsueh Pao/Acta Electronica Sinica",
        "year": 2002
    },
    "sLnvEvvt": {
        "id": "sLnvEvvt",
        "title": "Spanning tree-based protection capacity allocation algorithm for optical networks",
        "abstract": "One novel protection capacities reservation algorithm is proposed. Through reserving protection capacities in all trunks and partial chords on one pre-created spanning tree, the proposed algorithm assures that every node-pair on network keeps connection by at least two diverse protection routes, which can protect the networks from failing in case of the single link or node failure event.",
        "keywords": [
            "Algorithm",
            "Chord",
            "Optical network",
            "Protection capacity network",
            "Spanning tree"
        ],
        "authors": [
            {
                "name": "Mianfeng Lin",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jianwu He",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Laifu Fang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Tien Tzu Hsueh Pao/Acta Electronica Sinica",
        "year": 2002
    },
    "jkounsQ4": {
        "id": "jkounsQ4",
        "title": "Analysis of error detection codes in optical transport networks",
        "abstract": "Based on burst error model, the mathematical expressions for the probability of occurrence of a block error and the probability of detecting a block error, as well as the detection efficiency. Analyses and simulations to determine the maximum BER that can be detected (i.e., the saturation BER) and the minimum detection efficiency are given. Conclusions are drawn as follows: 2 × BIP-4 EDC can satisfy the performance monitoring requirement for each tandem connection. When real-time BER measurement estimation is not required, 8 × BIP-1 EDC is acceptable and 6 dB extra saturation BER is provided.",
        "keywords": [
            "Bit interleaved parity",
            "Error detecting code",
            "Optical transport network"
        ],
        "authors": [
            {
                "name": "Han Li",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "JianQuan Wang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Beijing Youdian Daxue Xuebao/Journal of Beijing University of Posts and Telecommunications",
        "year": 2002
    },
    "lEpXCD7x": {
        "id": "lEpXCD7x",
        "title": "Routing and wavelength assignment for survivability in optical networks",
        "abstract": "This paper presents a routing and wavelength assignment for survivability (RWAS) algorithm in optical networks. The attentions of most previous RWA algorithms focus on traffic balance, blocking performance, and network resource utilization, which are key performances of optical networks. However, with the development of DWDM systems and the increase of traffics in optical network, services survivability and network survivability must be paid much more attentions to. RWAS considers services survivability while routing and assigning wavelength(s) for a set of connections, which perhaps has not better resources utilization and blocking performances, but assures that as many service connections as possible can be restored in the current network in the case of any single link failure.",
        "keywords": [
            "distributed connection management",
            "optical networks",
            "restoration",
            "routing and wavelength assignment for survivability (rwas)",
            "survivability",
            "resource utilization"
        ],
        "authors": [
            {
                "name": "Jianwu He",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Mianfeng Lin",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Proceedings of SPIE - The International Society for Optical Engineering",
        "year": 2002
    },
    "LkLAecse": {
        "id": "LkLAecse",
        "title": "Design and Implementation of Intelligent Optical Network Management System",
        "abstract": "Intelligent optical network (ION) is deemed the representation of next generation optical networks which can realize fast establishment of connections, automatic resource discovery, traffic engineering and many other intelligent functions. Compared with traditional network management, ION management has some new characteristics due to the introduction of intelligent control plane and deserves deeper research. In this paper, we proposed an inter-domain layered ION management system scheme dealing with the multi-domain network environment. And the management information models designed for ION are presented, especially that for the control plane and three connection types. Then we discuss the key technologies which we use to implement the ION management system, for instance DML, Java and CORBA. At last, the simulation results of the ION management system are showed.",
        "keywords": [
            "control plane",
            "intelligent optical network (ion)",
            "inter-domain network management system (inms)",
            "next generation networking",
            "intelligent control",
            "dml",
            "management system",
            "environmental management",
            "intelligent systems",
            "java",
            "intelligent networks",
            "corba",
            "network management",
            "information model",
            "technology management",
            "traffic engineering",
            "information management"
        ],
        "authors": [
            {
                "name": "Hongsheng Song",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Yunbin Xu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Xuan Gui",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "International Conference on Communication Technology Proceedings, ICCT",
        "year": 2003
    },
    "ulcdfdyZ": {
        "id": "ulcdfdyZ",
        "title": "Information model for connection management in automatic switched optical network",
        "abstract": "The three types of connections (Permanent Connection, Soft Permanent Connection and Switched Connection) provided by Automatic Switched Optical Network (ASON) can adapt the requirement of different network services. Management and maintenance of these three connections are the most important aspect of ASON management. The information models proposed in this paper are used for the purpose of ASON connection management. Firstly a new information model is proposed to meet the requirement for the control plane introduced by ASON. In this model, a new class Control Network Element (NE) is given, and the relationship between the Control NE and the transport NE is also defined. Then this paper proposes information models for the three types of connections for the first time, and analyzes the relationship between the three kinds of connections and the basic network transport entities. Finally, the paper defines some CORBA interfaces for the management of the three connections. In these interfaces, some operations such as creating or releasing a connection are defined, and some other operations can manage the performance of the three kinds of connections, which is necessary for a distributed management system.",
        "keywords": [
            "Automatic switched optical network",
            "Permanent connection",
            "Soft permanent connection",
            "Switched connection"
        ],
        "authors": [
            {
                "name": "Yunbin Xu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Hongsheng Song",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Xuan Gui",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "High Technology Letters",
        "year": 2004
    },
    "6w3kv4TW": {
        "id": "6w3kv4TW",
        "title": "GMPLS signaling extension for multi-granularity optical switching node",
        "abstract": "The multi-granularity labels has been defined by Internet engineering task force (IETF), but the corresponding signaling process has not been standardized up to now. A new generalized multi-protocol label switching based signaling mechanism, which could be used for multi-granularity optical networks to create, release and modify its optical paths under the service-driven model, was proposed. With the help of communication finite state machine (CFSM) to analyze the signaling mechanism, we conclude that the signaling mechanism proposed could be satisfied in the dynamic requirement of different granularity optical paths.",
        "keywords": [
            "Communication finite state machine",
            "Generalized multi-protocol label switching",
            "Label switching path",
            "Multi-granularity switching"
        ],
        "authors": [
            {
                "name": "Yunbin Xu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Hongsheng Song",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Beijing Youdian Daxue Xuebao/Journal of Beijing University of Posts and Telecommunications",
        "year": 2004
    },
    "rFoaQGRT": {
        "id": "rFoaQGRT",
        "title": "Resource assignment in multi-granularity switching optical network",
        "abstract": "Multi-granularity switching is an attractive technology, which can not only save the network cost but also realize traffic grooming. There are many different sizes tunnels available in multi-granularity optical network, so resource assignment becomes very important for lightpath establishment. In this paper, we focus on the research in waveband switching (WBS) network. Firstly the node structure and multi-granularity connections are analyzed, and the term of RRA (routing and resource assignment) is proposed to state the problem of lightpath establishment. And a kind of resource assignment policy for RRA is proposed according to the tunnel granularity. As a part of resource assignment in WBS network, the problem of waveband paths assignment is discussed and several new dynamic algorithms are proposed. They are SBP (shortest waveband path), FBP (first-fit waveband path), LBP (longest waveband path) and LBC (longest waveband combination) algorithms. In our numerical simulations, some factors that impact the performance of network are analyzed, such as waveband assignment algorithm, switching ratios and waveband partition. And also some useful conclusions are drawn, which are instructive for the design and implementation of multi-granularity network.",
        "keywords": [
            "multi-granularity optical cross-connect (mg-oxc)",
            "multi-granularity switching",
            "routing and resource assignment (rra)",
            "waveband assignment algorithm",
            "waveband switching (wbs) network",
            "algorithms",
            "networks",
            "numerical simulation",
            "traffic grooming"
        ],
        "authors": [
            {
                "name": "Hongsheng Song",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Xuan Gui",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Proceedings of SPIE - The International Society for Optical Engineering",
        "year": 2004
    },
    "3CcAoR0L": {
        "id": "3CcAoR0L",
        "title": "Analysis and design of optical virtual private networks (OVPN) over ASON",
        "abstract": "This paper studies design and provision problem of OVPN over ASON. Some special issues are dedicated, including address translation, access authentication, OVPN membership management. UNI framework which supports OVPN over ASON is presented. And procedures of OVPN operation are designed.",
        "keywords": [
            "ason",
            "network reference model",
            "ovpn",
            "service requirements",
            "study design",
            "networks"
        ],
        "authors": [
            {
                "name": "Xuan Gui",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Yunbin Xu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Hongsheng Song",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Proceedings of SPIE - The International Society for Optical Engineering",
        "year": 2004
    },
    "y46ou6I6": {
        "id": "y46ou6I6",
        "title": "Analysis, design and implementation of ASON management system",
        "abstract": "To manage Automatically Switched Optical Network (ASON), management requirements were analyzed first, including heterogeneous networks management, control plane components and new kind of connection management. Management information classes were abstracted based on these requirements. A two-layer management architecture was designed, in which Inter-domain Network Management System (INMS) provided an integrated view and Network Management System (NMS) focused on management of certain network domain. An implementation of ASON management system was described, whose interfaces were based on CORBA and GUI based on Java. At last, a test platform which demonstrated multi-domain, connection and control plane management was shown.",
        "keywords": [
            "Automatic switched optical network (ASON)",
            "Control plane",
            "Management information model",
            "Network management system"
        ],
        "authors": [
            {
                "name": "Xuan Gui",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Yunbin Xu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Hongsheng Song",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "High Technology Letters",
        "year": 2005
    },
    "7fxCTDMQ": {
        "id": "7fxCTDMQ",
        "title": "ASON control link bandwidth requirements analysis",
        "abstract": "It is important to know the control link bandwidth requirements because the control messages should be reliably transported and at the same time the capital expenditure must be saved. The implementation methods of the control link and the composition of the control protocol traffic flow are analyzed. And we introduce a practicable software simulation-based ASON network framework and node structure. Then based on this simulation platform simulations of the control link bandwidth requirements in ASON under different conditions is realized. Relationship between the control link traffic rate and the network traffic load of the ASON network is described. Relationship between the control link traffic rate and the quantity of the users in ASON network is described as well. The bandwidth requirements of the control link under different connection setup time limits are also analyzed. We also indicate that traffic blocking can significantly increase the control overhead. In the end the approximate equations to describe these relations are developed to help the real ASON network design. © by Fachverlag Schiele & Schön 2005.",
        "keywords": [],
        "authors": [
            {
                "name": "Jianping Li",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Peiyuan Lee",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Journal of Optical Communications",
        "year": 2005
    },
    "KEoAZAnD": {
        "id": "KEoAZAnD",
        "title": "Dynamic traffic grooming with adaptive routing in optical WDM mesh networks",
        "abstract": "In this paper, we propose two novel dynamic adaptive routing grooming algorithms for optical WDM mesh networks using the fixed alternate routing (FAR) approach. The algorithms consider both load balance and resources utilization in the network and use FAR mechanism to reduce computation complexity and transmission delay. The simulation results show that the network performance can be improved significantly by these algorithms.",
        "keywords": [
            "adaptive routing (ar)",
            "routing and wavelength assignment (rwa)",
            "traffic grooming",
            "wavelength division multiplex (wdm)",
            "load balance",
            "algorithms",
            "networks",
            "adaptive routing",
            "computational complexity",
            "network performance",
            "resource utilization",
            "wavelength division multiplexing",
            "mesh network"
        ],
        "authors": [
            {
                "name": "Shanguo Huang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Mingxia Bo",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Proceedings of SPIE - The International Society for Optical Engineering",
        "year": 2005
    },
    "AvlPsb9D": {
        "id": "AvlPsb9D",
        "title": "A novel wavelength availability advertisement based ASON routing protocol implementation",
        "abstract": "A novel wavelength availability advertisement based ASON routing protocol implementation is proposed in this paper which is derived from Open Shortest Path First protocol (OSPF) version 2. It can be applied to ASON network with a single control domain and can be easily extended to support routing in the multi-domain scenarios. Two new types of link state advertisement (LSA) are suggested for disseminating wavelength availability and network topology information. The OSPF mechanisms are inherited to ensure that the routing messages are delivered more reliably and converged more quickly while with fewer overheads. The topology auto discovery is realized through LSA flooding interacting with auto neighbor discovery using Link Management Protocol. The new LSA formats are given and how the link state database (LSD) is comprised is described. The new data structures proposed include topology resource list, adjacency list and route table. Then we analyze the differences of ASON in link state exchange, routing information flooding procedure, flushing procedure and new resources participating, i.e. new links or nodes join in an existing ASON. The link or node failure and recovery effect and how to deal with them are settled as well. In order to adopt different Routing and Wavelength Assignment (RWA) algorithms, a standard and efficient interface is designed. After extensive simulation we give the numerical analysis and come to the following conclusions: wavelength availability information flooding Convergence Time is about 30 milliseconds and it is not affected by RWA algorithms and the call traffic load; routing Protocol Average Overhead rises linearly with the increase of traffic load; Average Connection Setup Time decreases with the increase of traffic load because of the decrease of Average Routing Distance of the successfully lightpaths; Wavelength availability advertisement can greatly promote the blocking performance of ASON in relatively low traffic load; ASON operator can make a good trade off between the wavelength availability advertisement Protocol Average Overhead and Blocking Probability by adopting and adjusting the routing update triggers; and the last is that wavelength availability advertisement throughout the optical network is applicable and our ASON routing protocol implementation could be applied in ASON when its scale is not too large and if the calls do not arrive and leave the network in a too frequent pace.",
        "keywords": [
            "ason",
            "flooding trigger",
            "optical communication",
            "ospf",
            "rwa",
            "wavelength information distribution",
            "databases",
            "interfaces",
            "open shortest path first",
            "network topology",
            "numerical analysis",
            "routing protocol",
            "algorithms",
            "neighbor discovery",
            "data structure",
            "networks"
        ],
        "authors": [
            {
                "name": "Jianping Li",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Juan Liu",
                "org": "Motorola China Electronics Ltd.(Motorola (China) Electronics Ltd.),Tianjin,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Proceedings of SPIE - The International Society for Optical Engineering",
        "year": 2005
    },
    "8LRY4Ao0": {
        "id": "8LRY4Ao0",
        "title": "Performance analysis and improvement in GMPLS-based Multi-granularity optical network",
        "abstract": "A novel switching architecture of multi-granularity optical cross-connects (MG-OXCs) is proposed, which cooperate with the generalized multi-protocol label switching (GMPLS) control plane. We study the performance using both analysis and simulations. The result demonstrates a significant cost reduction that could be achieved for a moderately small reduction of throughput.",
        "keywords": [
            "ason",
            "control plane",
            "gmpls",
            "intelligent optical networks",
            "lrm",
            "multi-granularity",
            "ospf-te",
            "rc",
            "rsvp-te",
            "signalling",
            "optical cross connect"
        ],
        "authors": [
            {
                "name": "Aiping Yang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Ling Yun",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Proceedings of SPIE - The International Society for Optical Engineering",
        "year": 2005
    },
    "EASXvYeS": {
        "id": "EASXvYeS",
        "title": "Comparative study of signalling and routing schemes in ASTN",
        "abstract": "We have developed a GMPLS-based software platform with Intelligence Optical Network (ION) capabilities to simulate different technologies and protocols of ASTN. For optical transport network (OTN) based ASTN, usually named as automatically switched optical network (ASON), two signalling schemes, Explicit Label Control (ELC) and Backward Wavelength Reservation with N retries (BWR-N), are considered. The ELC is associated with two routing and wavelength assignment (RWA) policies, the shortest path first routing (Dijkstra algorithm) with first-fit (FF) wavelength assignment and the fixed path least congestion (FPLC) routing with FF wavelength assignment. For the BWR-N, the route is determined by Dijkstra's algorithm and the wavelength is selected through signalling process. For SDH/SONET-based ASTN, we also consider two signalling scheme, the ELC and the Forward Timeslot Reservation (FIR). Similar simulations have been performed. These signalling and routing schemes are evaluated by several crucial metrics, such as the blocking probability, the setup time, the average routing length of the connections and the control overhead. Some significant conclusions have been presented by this paper.",
        "keywords": [
            "astn",
            "blocking probability",
            "bwr",
            "control overhead",
            "dijkstra",
            "elc",
            "ff",
            "fplc",
            "ftr",
            "routing",
            "routing length",
            "setup time",
            "signalling",
            "networks",
            "dijkstra s algorithm",
            "optical transport network"
        ],
        "authors": [
            {
                "name": "Hui Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Yuanyuan Ma",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Dongfeng Mao",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Proceedings of SPIE - The International Society for Optical Engineering",
        "year": 2005
    },
    "haY6iE5z": {
        "id": "haY6iE5z",
        "title": "Management information model design for ASON network resource",
        "abstract": "Automatic Switched Optical Network(ASON) is the key technology for the next generation optical network, and the recommendations for ASON are also developed by ITU-T, but for management plane, the related recommendations have not been constituted. In this paper, the management information mode for network layer and control plane resources are proposed based on the requirements for ASON network management. The managed object model of network layer resource could be used for the end-to-end connections management in multi-domain networks. The model for the control plane could be used for the management of control Network Elements (NEs) and control channels, this model could also be used for route areas division in control plane and configuring and performance inspecting for the control modules in the control NEs.",
        "keywords": [
            "Automatic Switched Optical Networks (ASON)",
            "Control plane",
            "Network management",
            "Resource information mode"
        ],
        "authors": [
            {
                "name": "Yunbin Xu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Hongsheng Song",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Xuan Gui",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Dianzi Yu Xinxi Xuebao/Journal of Electronics and Information Technology",
        "year": 2005
    },
    "P0IFTiqa": {
        "id": "P0IFTiqa",
        "title": "The realization and function evaluation of the LCAS technology in MSTP system",
        "abstract": "The technology of link capacity adjustment scheme (LCAS) is one of the key technologies of the next generation of MSTP solution in MAN.In this paper, it first summarizes the next generation of MSTP, then introduces the EoS network testlab and expatiates the fuction designing for the testlab according to the characteristic of LCAS,then particularly describes critical points of the realization. Then, it analyses the plan of the function testing and brings forword some evaluations a of the LCAS technology points based on the testing result. Finally,it gives some conclusion for the LCAS technology.",
        "keywords": [
            "networks",
            "functional testing",
            "critical point"
        ],
        "authors": [
            {
                "name": "Miao Cao",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Liang Feng",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Proceedings of SPIE - The International Society for Optical Engineering",
        "year": 2005
    },
    "zYfyS9V2": {
        "id": "zYfyS9V2",
        "title": "Novel ASON routing implementation",
        "abstract": "An OSPF-based ASON routing implementation was proposed. In the implementation a wavelength LSA and network node LSA were extended to distribute wavelength and topology information. The topology was discovered automatically and routing messages were delivered reliably. In addition, the RWA interface was designed to introduce RWA algorithms easily. The simulation results show that the routing protocol implementation could converge rapidly and could be extended easily at low protocol overhead. The routing information flooding trigger strategies and the feasibility of flooding wavelength information throughout the network are also analyzed.",
        "keywords": [
            "ASON",
            "Flooding trigger",
            "OSPF",
            "RWA",
            "Wavelength information distribution"
        ],
        "authors": [
            {
                "name": "Jianping Li",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Aiping Yang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Tongxin Xuebao/Journal on Communications",
        "year": 2006
    },
    "JRuXuti0": {
        "id": "JRuXuti0",
        "title": "Two new metrics for evaluating the routing advertisement triggers",
        "abstract": "The existing metrics to evaluate the advertisement triggers could not judge the trigger's impact on the routing bandwidth requirement. To solve this problem we introduce two new metrics, i.e. Average Routing Update Overhead (ARUO) and Maximum Routing Update Overhead (MRUO). We re-evaluate the existing triggers using not only blocking probability but also ARUO and MRUO.",
        "keywords": [
            "probability"
        ],
        "authors": [
            {
                "name": "Jianping Li",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Fangdi Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Peng Lin",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "International Conference on Communication Technology Proceedings, ICCT",
        "year": 2006
    },
    "C6bCNc60": {
        "id": "C6bCNc60",
        "title": "A study of waveband assignment in waveband switching optical network",
        "abstract": "Tremendous internet traffic makes DWDM (Dense Wavelength Division Multiplexing) technology popularly applied in optical network and the scale of optical cross-connect (OXC) becomes larger. In order to save node cost and realize traffic grooming, waveband switching (WBS) with many new algorithms for lightpath establishment has been proposed. In this paper, the concept of RWA (routing and wavelength assignment) in wavelength-routed network is extended to RRA (routing and resource assignment) in hierarchical optical network. And a kind of resource assignment policy for RRA is proposed according to the path granularity. Then several new dynamic waveband assignment algorithms for sequential multi-granularity OXC (MG-OXC) in WBS network without wavelength converters are presented. They are SBP (shortest waveband path), FBP (first-fit waveband path), LBP (longest waveband path) and LBC (longest waveband combination) algorithms. Numerical results show that LBP algorithm is simple and more effective for middle-scale WBS optical network and LBC algorithm is suitable for large-scale one.",
        "keywords": [],
        "authors": [
            {
                "name": "Hongsheng Song",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wenyan Jin",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Journal of Optical Communications",
        "year": 2006
    },
    "gxbpi8DP": {
        "id": "gxbpi8DP",
        "title": "Multicast in Splitter-Sharing Optical Network",
        "abstract": "In optical multicast, because of the high cost and complex architecture of multicast capable (MC) node, splitter-sharing switch structure is introduced. To accommodate to this structure, a multicast routing algorithm in splitter-sharing optical network and a changing link weight policy to balance traffic throughput are proposed. At the same time, by extending RSVP and OSPF, an optical multicast protocol mechanism is provided. Simulations in NSFNET show when the number of splitters is 25% of that demanded by traditional MC nodes, the performance has been close to the ideal circumstance. Using changing link weight can improve the performance fairly but has a longer setup time.",
        "keywords": [
            "telecommunication switching",
            "changing link weight",
            "multicast routing algorithm",
            "optical fibre networks",
            "splitter-sharing optical network",
            "changing link weight policy",
            "splitter-sharing switch structure",
            "multicast capable node",
            "multicast protocols",
            "optical multicast protocol mechanism"
        ],
        "authors": [
            {
                "name": "Peng Jia",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jianping Li",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jiaying Wang",
                "org": "Zte(ZTE Corporation,ZTE Corp.),Shenzhen,China"
            }
        ],
        "venue": "Beijing",
        "year": 2006
    },
    "8qxUM4cJ": {
        "id": "8qxUM4cJ",
        "title": "Research of the Survival Mechanisms in ASON",
        "abstract": "This paper focuses on the survival mechanisms against single link failure for optical QoS services in ASON (Automatically Switched Optical Network). The new protection and restoration methods and optical QoS services enabled by ASON also bring new requirements. Correspondingly, the component functions in ASON control plane, such as Connections Controller, Link Resource manager and Routing Controller are extended. According to the survival level of the QoS service requested, we divide the traffic into five types, viz. 1+1, 1:1, shared-mesh, rerouting and extra traffic. Optical QoS services and resource preemption are realized in our simulation platform. Extensive simulations are performed concerning failure localization time, failure recovery time, recovery success ratio and network resource utilization.",
        "keywords": [
            "automatically switched optical network",
            "failure recovery",
            "optical qos services",
            "resource utilization",
            "local time",
            "networks",
            "resource manager"
        ],
        "authors": [
            {
                "name": "Yu Deng",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jianping Li",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Ludi Zheng",
                "org": "Bell Labs Research China(Bell Labs. Research China,Bell Labs Research China),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Proceedings of SPIE - The International Society for Optical Engineering",
        "year": 2006
    },
    "VfYxQIZ3": {
        "id": "VfYxQIZ3",
        "title": "Wavelength reservation in wavelength-routed optical networks",
        "abstract": "A novel wavelength reservation protocol is proposed for wavelength-continuous lightpaths establishment in the wavelength-routed optical networks. The protocol uses backward reservation protocol (BRP) with intermediate retry to reduce the chance of blocking. BRP is normally considered to be better than forward reservation protocol (FRP) from the blocking point of view. Intermediate retries make it more efficient in that respect. We show through simulation that the protocol improves the success rate in lightpaths setup considerably without much incrementing the lightpath setup delay.",
        "keywords": [],
        "authors": [
            {
                "name": "Jianping Li",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jielan Xie",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Journal of Optical Communications",
        "year": 2006
    },
    "FrZsW1KV": {
        "id": "FrZsW1KV",
        "title": "Novel virtual source based multicast routing algorithm in WDM networks with sparse light splitting",
        "abstract": "Wavelength-division multiplexed (WDM) networks using wavelength-routing are considered to be potential candidates for the next generation wide area backbone networks. A node in the network may have both wavelength conversion and splitting capabilities which is called as virtual source. It is assumed that virtual sources are limited in number and are distributed evenly in the network. One virtual source based algorithm has been proposed in previous work. But this scheme will leads to high tree Cost and the virtual source is easy to be exhausted. In this paper, we propose two improved virtual source based algorithms that constructs all-optical multicast trees. We directed detailed simulations. The results show that our mechanism builds light-trees with the least wavelength channel cost and with the smallest number of wavelengths under certain number of multicast sessions.",
        "keywords": [
            "wavelength division multiplexing"
        ],
        "authors": [
            {
                "name": "Peng Lin",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Shuai Shi",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jianping Li",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "International Conference on Communication Technology Proceedings, ICCT",
        "year": 2006
    },
    "JPcnCm2j": {
        "id": "JPcnCm2j",
        "title": "Research of resource reservation schemes of RSVP-TE in ASON",
        "abstract": "Various resource reservation schemes in RSVP-TE (Resource Reservation Protocol-Traffic Engineering) which is the most promising candidate for the signalling protocol of ASON (Automatically Switched Optical Network), viz. FRP (Forward Reservation Protocol), BRP (Backward Reservation Protocol), and the proposed scheme named BRP with Single-Wavelength-Reservation are presented. Based on the simulation and comparative analysis, it is concluded that the proposed scheme takes the advantages of both FRP and BRP. It is of low control overhead and short service set-up time, and can exploit the network resource efficiently and alleviate service blocking probability.",
        "keywords": [
            "ASON",
            "BRP",
            "BRP with single-wavelength-reservation",
            "FRP",
            "RSVP-TE"
        ],
        "authors": [
            {
                "name": "Yu Deng",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Lei Zhao",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "XIE Jie-lan",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "GU Wan-yi",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Guangzi Xuebao/Acta Photonica Sinica",
        "year": 2007
    },
    "awrJtV7t": {
        "id": "awrJtV7t",
        "title": "Adaptability of optical multi-service transport networks",
        "abstract": "Optical multi-service transport networks are on the edge of new round of revolution from automation to autonomy. The viewpoint of adaptability is proposed as an important topic to understand future optical networks in this paper. Related studies have been deployed in the aspects of service-oriented, traffic-oriented and media-oriented adaptability.",
        "keywords": [
            "adaptability",
            "all-optical",
            "automatically switched optical network",
            "multi-service",
            "transport network",
            "networks"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Proceedings of SPIE - The International Society for Optical Engineering",
        "year": 2007
    },
    "9JmXHVR4": {
        "id": "9JmXHVR4",
        "title": "Resource advance reservation mechanism in intelligent optical network",
        "abstract": "To apply advance reservation in intelligent optical network, the related protocols of GMPLS were extended. Three routing and wavelength assignment algorithms, which were shortest path, link weight change and layered graph, were provided. Meanwhile a classification of shared wavelengths and dedicated wavelengths for non-advanced reservation was proposed. Simulations show layered graph is best with low traffic loads. Wavelength-dedicated mechanism can improve the performance of non-advance reservation to a certain degree; but it will cause the high block of advance reservation and inefficient resource utilization.",
        "keywords": [
            "Advance reservation",
            "Intelligent optical network",
            "Layered graph",
            "Protocol"
        ],
        "authors": [
            {
                "name": "Peng Jia",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Bi Feng Mo",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "GU Wan-yi",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Bandaoti Guangdian/Semiconductor Optoelectronics",
        "year": 2007
    },
    "4Wg7Eylu": {
        "id": "4Wg7Eylu",
        "title": "A novel P-cycle protection algorithm for dual link failures in mesh optical networks",
        "abstract": "The fundamental of the dual link failures protection with P-cycles in mesh optical networks was introduced. The configuration strategy of the protection cycles with P-cycles in networks with at least 3 degrees was then discussed. Furthermore, a heuristic algorithm based on the working resource distribution and the straddling links efficiency was proposed. And the proposed algorithm was simulated in COST239 network under static traffic model on OPNET simulation platform. The results show that the proposed algorithm has shorter restoration time and lower capacity redundancy.",
        "keywords": [
            "Dual link failure",
            "Mesh optical network",
            "P-cycle",
            "Protection",
            "Stride link efficiency"
        ],
        "authors": [
            {
                "name": "ZANG Yun-hua",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jianping Li",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "GU Wan-yi",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "ZHENG Lu-di",
                "org": "Bell Labs Research China(Bell Labs. Research China,Bell Labs Research China),Beijing,China"
            }
        ],
        "venue": "Beijing Youdian Daxue Xuebao/Journal of Beijing University of Posts and Telecommunications",
        "year": 2007
    },
    "ERyTEWd2": {
        "id": "ERyTEWd2",
        "title": "Research on the multi-granularity optical switching node with tunable wavelength converters",
        "abstract": "The characteristics of the multi-granularity optical cross connect (MG-OXC) node with the tunable wavelength converters is analyzed. A new dynamic routing and wavelength assignment algorithm which is applied in multi-granularity optical switching network is also proposed. The performance of the MG-OXC with tunable optical converters, compared with traditional OXC and MG-OXC, is evaluated with help of numerical calculations under NSFNET topology. The results show that the performance of the network with MG-OXC with tunable wavelength converters is superior to that of the network composed with only traditional OXC and MG-OXC.",
        "keywords": [
            "Dynamic routing and wavelength assignment",
            "Multi-granularity optical switching",
            "Tunable wavelength converter"
        ],
        "authors": [
            {
                "name": "XU Yue-gang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "HAN Da-hai",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "GU Wan-yi",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Beijing Youdian Daxue Xuebao/Journal of Beijing University of Posts and Telecommunications",
        "year": 2007
    },
    "4MquWtEf": {
        "id": "4MquWtEf",
        "title": "Optimal path selection for virtual concatenation in SDH networks",
        "abstract": "The path selection for members of virtual concatenation group is non-deterministic polynomial(NP) complete problem in synchronous digital hierarchy(SDH) networks applying virtual concatenation technology. Two-sided constrained optimal path (TSOP) algorithm was proposed to maintain high utilization of network resources and ensure the new adding VC-n to satisfy the differential delay constraints. Simulations results showed the performance of TSOP algorithm is superior to those of k-shortest path algorithm and modified-link-weight k-shortest path algorithm.",
        "keywords": [
            "Link capacity adjustment scheme",
            "Two-sided constrained optimal path algorithm",
            "Virtual concatenation"
        ],
        "authors": [
            {
                "name": "XU Yue-gang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "HAN Da-hai",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "GU Wan-yi",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Beijing Youdian Daxue Xuebao/Journal of Beijing University of Posts and Telecommunications",
        "year": 2007
    },
    "zZr0cgHz": {
        "id": "zZr0cgHz",
        "title": "Evaluation of GMPLS controlled multi-granularity automatically switched optical network",
        "abstract": "The Single-granularity Automatically Switched Optical Network (SASON) has been extensively researched in recent years. Yet little work has been done in the research of integrating multi-granularity Optical Cross-Connects (OXCs) with ASON architecture, that is Multi-granularity ASON (MASON). In this paper, Generalised Multi-Protocol Label Switching (GMPLS) controlled MASON is evaluated through simulations. For the first time MASON is compared with SASON. The results reveal that MASON is more scalable and does better in cost saving. But its advantages are at the expenses of longer connection setup time, worse blocking performance and more sensitivity to the inaccuracy of the routing information. Copyright © 2007 John Wiley & Sons, Ltd.",
        "keywords": [],
        "authors": [
            {
                "name": "Jianping Li",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Ling Yun",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "European Transactions on Telecommunications",
        "year": 2008
    },
    "lQrnREnW": {
        "id": "lQrnREnW",
        "title": "Performance of a threshold-based dynamic priority bandwidth allocation scheme in metro area networks",
        "abstract": "In this paper, we probe into the traditional multiple class selective discard scheme and Multiple Class Buffer Priority (MCBP) algorithm based on the Markov Modulated Poisson Process (MMPP) traffic, analyse the impact of the arriving traffic with long-duration burstiness on multi-priority system performance. Then, a threshold-based dynamic priority bandwidth allocation scheme suitable for SDH/SONET-based Metro Area Networks is proposed, the use of threshold decreases about 50of the scheme is tractable and can provide relatively accurate result, which is suitable for the burstiness circumstance under the model of SDH/SONET-based MANs. We verify the effect of dynamic bandwidth allocation under the restriction of threshold through simulation, the result shows that the TDPBA scheme can guarantee the high QoS service getting efficient transmission bandwidth in the premise of sacrificing the performance of low priority service. Copyright © 2008 Watam Press.",
        "keywords": [
            "MANs",
            "MCBP",
            "MMPP",
            "SDH",
            "TDPBA"
        ],
        "authors": [
            {
                "name": "Dahai Han",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Dynamics of Continuous, Discrete and Impulsive Systems Series B: Applications and Algorithms",
        "year": 2008
    },
    "GNuwkVaN": {
        "id": "GNuwkVaN",
        "title": "Distributed wavelength reservation method research and analysis in dynamic optical network",
        "abstract": "Three methods of distributed reservation named FQRP (Forward Queue Reservation Protocol), FRP-ë (Single Wavelength Forward Reservation Protocol) and Extension of FRP in optical network are proposed in this paper. The three methods make some improvements on the traditional FRP (Forward Reservation Protocol) and BRP (Backward Reservation Protocol). They are described, analyzed and simulated in detail in this paper. The simulation results show that they do have advantages over the traditional two methods. Each has its own advantage. © 2008 SPIE.",
        "keywords": [
            "blocking probability",
            "brp",
            "delay upper limit",
            "extension of frp",
            "fqrp",
            "frp",
            "frp-ë",
            "trying upper limit"
        ],
        "authors": [
            {
                "name": "Li Li.",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Dahai Han",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Yongli Zhao",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Miao Wang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Proceedings of SPIE - The International Society for Optical Engineering",
        "year": 2008
    },
    "rq6iOOwk": {
        "id": "rq6iOOwk",
        "title": "Implementation of bandwidth on demand service on adaptive service provisioning platform of transport networks",
        "abstract": "A novel framework named Service Plane is put forward in transport networks on the basis of the principle of adaptive multi-services provisioning platform. The flexible implementation of service and the expansibility of framework is what we concern most in this kind of Service Plane. Here we raise the core algorithms of bandwidth on demand service on this platform, simulation testbed and the implementation result are also presented in this paper. © 2008 SPIE.",
        "keywords": [
            "amson",
            "bod",
            "distributed provision",
            "service plane",
            "slb",
            "web service",
            "algorithms",
            "networks"
        ],
        "authors": [
            {
                "name": "Feng Yuan",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Dahai Han",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Haibin Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Xiuzhong Chen",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wenyu Zhao",
                "org": "MII(MII),Beijing,China"
            }
        ],
        "venue": "Proceedings of SPIE - The International Society for Optical Engineering",
        "year": 2008
    },
    "uOdhpCIL": {
        "id": "uOdhpCIL",
        "title": "O3-SAN based on resource joint scheduling model in service-oriented optical networks",
        "abstract": "Traditional SAN (Storage Area Networks) are deployed by organization and used by themselves. These SAN are characterized by SAN islands-pockets of noninterconnected SAN infrastructure and SMEs (Small and medium-sized enterprises) cannot afford the expensive private SAN. The O3-SAN are Open, Optimized and Optical SAN architecture based on the service-oriented optical networks. A novel model of joint scheduling of optical resource (lightpath) and storage devices are presented, and then O3-SAN are implemented on the service plane based on web services (ws-sp). Results are showed and explained finally.",
        "keywords": [
            "optical resource",
            "medium-sized enterprise",
            "Storage Area Networks",
            "noninterconnected SAN infrastructure",
            "SAN islands-pockets",
            "Optical SAN architecture",
            "resource joint scheduling model",
            "joint scheduling",
            "Traditional SAN",
            "expensive private SAN",
            "service-oriented optical network"
        ],
        "authors": [
            {
                "name": "Xiuzhong Chen",
                "org": "Beijing University of Posts and Telecommunications, Beijing, China P.R."
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications, Beijing, China P.R."
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications, Beijing, China P.R."
            }
        ],
        "venue": "ICAIT '08 Proceedings of the 2008 International Conference on Advanced Infocomm Technology",
        "year": 2008
    },
    "5N1w5zrX": {
        "id": "5N1w5zrX",
        "title": "Routing on pre-configured topology for dynamic optical networks",
        "abstract": "Dynamic optical networks are the physical basis of the development and evolution of the next generation network (NGN). By pre-configuring the resources of dynamic optical networks, we can reconstruct the topology, increase the number of direct routes, and then optimize the performance of routing and forwarding. This article analyzes the characteristics of the pre-configuration process, and gives the corresponding mathematical description. A planning scheme of resource pre-configuration that forms a pre-configured topology different from physical topology and virtual topology has been introduced for dynamic optical networks. Two dynamic routing algorithms have been run on the pre-configured topology. Simulations results show that the connection establishing time of the control plane could be significantly reduced by using the resource pre-configuration strategy.",
        "keywords": "",
        "authors": [
            {
                "name": "Yongli Zhao",
                "org": "Key Laboratory of Optical Communication and Lightwave TechnologiesMinistry of Education, Beijing University of Posts and TelecommunicationsBeijingPeople’s Republic of China;"
            },
            {
                "name": "Jie Zhang",
                "org": "Key Laboratory of Optical Communication and Lightwave TechnologiesMinistry of Education, Beijing University of Posts and TelecommunicationsBeijingPeople’s Republic of China;"
            },
            {
                "name": "Dahai Han",
                "org": "Key Laboratory of Optical Communication and Lightwave TechnologiesMinistry of Education, Beijing University of Posts and TelecommunicationsBeijingPeople’s Republic of China;"
            },
            {
                "name": "Lei Wang",
                "org": "Key Laboratory of Optical Communication and Lightwave TechnologiesMinistry of Education, Beijing University of Posts and TelecommunicationsBeijingPeople’s Republic of China;"
            },
            {
                "name": "Wanyi Gu",
                "org": "Key Laboratory of Optical Communication and Lightwave TechnologiesMinistry of Education, Beijing University of Posts and TelecommunicationsBeijingPeople’s Republic of China;"
            },
            {
                "name": "Yuefeng Ji",
                "org": "Key Laboratory of Optical Communication and Lightwave TechnologiesMinistry of Education, Beijing University of Posts and TelecommunicationsBeijingPeople’s Republic of China;"
            }
        ],
        "venue": "Photonic Network Communications",
        "year": 2008
    },
    "ML3NmUtm": {
        "id": "ML3NmUtm",
        "title": "O<sup>3</sup>-SAN based on resource joint scheduling model in service-oriented optical networks",
        "abstract": "Traditional SAN (Storage Area Networks) are deployed by organization and used by themselves. These SAN are characterized by SAN islands-pockets of noninterconnected SAN infrastructure and SMEs (Small and medium-sized enterprises) cannot afford the expensive private SAN. The O3-SAN are Open, Optimized and Optical SAN architecture based on the service-oriented optical networks. A novel model of joint scheduling of optical resource (lightpath) and storage devices are presented, and then O3-SAN are implemented on the service plane based on web services (ws-sp). Results are showed and explained finally.",
        "keywords": [
            "web services",
            "storage are networks",
            "joint scheduling",
            "resource management",
            "service-oriented optical network"
        ],
        "authors": [
            {
                "name": "Xiuzhong Chen",
                "org": "beijing university of posts and telecommunications"
            },
            {
                "name": "Jie Zhang",
                "org": "beijing university of posts and telecommunications"
            },
            {
                "name": "Wanyi Gu",
                "org": "beijing university of posts and telecommunications"
            }
        ],
        "venue": "",
        "year": 2008
    },
    "PSQtx8Ob": {
        "id": "PSQtx8Ob",
        "title": "Blocking analysis of dynamic lightpath establishment based on multi-states reservation for wavelength-routed networks",
        "abstract": "Two methods of reservation namely ANIR (all nodes-initiated reservation) and MSR (multi-states reservation) are proposed and compared with SIR (source-initiated reservation) and DIR (destination-initiated reservation). The four methods of reservation are simulated in NSFNET and ARPA topologies. Numeric results show that the blocking probability of ANIR is lower than SIR, but the number of packages which it generates is larger, and the blocking probability of MSR is lower than DIR and SIR under light load. © 2008 SPIE.",
        "keywords": [
            "ANIR",
            "DIR",
            "MSR",
            "Resource reservation",
            "Signaling",
            "SIR",
            "Wavelength-routed networks"
        ],
        "authors": [
            {
                "name": "Yongli Zhao",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Li Li.",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Dahai Han",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Yu Yao",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Ting Liang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Proceedings of SPIE - The International Society for Optical Engineering",
        "year": 2008
    },
    "yRaL42W2": {
        "id": "yRaL42W2",
        "title": "Novel fault localization method for inter-domain node failure in automatic switched optical network",
        "abstract": "On the basis of research on fault localization in single-domain using link management protocol (LMP), a novel method to locate inter-domain node failure in automatic switched optical network (ASON) is proposed based on the communications between inter-domain nodes. The proposed method accomplishes the inter-domain fault localization by using distributed control plane in ASON, thus it is not dependent on transport plane's encoding manners and network manager's experience. Further the principle of our proposed method and the process of fault localization are set forth under different circumstances of inter-domain node failure.",
        "keywords": [
            "Automatic switched optical network (ASON)",
            "Fault localization",
            "Inter-domain node failure",
            "Link management protocol",
            "Multi-domain survivability"
        ],
        "authors": [
            {
                "name": "Yu Deng",
                "org": "State Key Laboratory of Information Photonics and Optical Communications(State Key Laboratory of Information Photonics and Optical Communications,Key Laboratory of Optical Communication and Lightwave Technologies),Beijing,China"
            },
            {
                "name": "ZHOU Xi-zeng",
                "org": "Yuan Ze University(Yuan Ze University,Yuan-Ze University ^),Chung-Li,Taiwan"
            },
            {
                "name": "Lei Zhao",
                "org": "State Key Laboratory of Information Photonics and Optical Communications(State Key Laboratory of Information Photonics and Optical Communications,Key Laboratory of Optical Communication and Lightwave Technologies),Beijing,China"
            },
            {
                "name": "ZANG Yun-hua",
                "org": "State Key Laboratory of Information Photonics and Optical Communications(State Key Laboratory of Information Photonics and Optical Communications,Key Laboratory of Optical Communication and Lightwave Technologies),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "State Key Laboratory of Information Photonics and Optical Communications(State Key Laboratory of Information Photonics and Optical Communications,Key Laboratory of Optical Communication and Lightwave Technologies),Beijing,China"
            },
            {
                "name": "GU Wan-yi",
                "org": "State Key Laboratory of Information Photonics and Optical Communications(State Key Laboratory of Information Photonics and Optical Communications,Key Laboratory of Optical Communication and Lightwave Technologies),Beijing,China"
            }
        ],
        "venue": "Guangdianzi Jiguang/Journal of Optoelectronics Laser",
        "year": 2008
    },
    "100S5m9s": {
        "id": "100S5m9s",
        "title": "The research of cloud computing based on service plane over optical networks",
        "abstract": "The implementation of Cloud Computing over optical networks faces many challenges and opportunities. A cloud computing architecture over optical networks is proposed based on the service plane. And the validity of the architecture we proposed was experimentally demonstrated in our Adaptive Multi-Service Optical Network testbed. © 2009 SPIE-OSA-IEEE.",
        "keywords": [
            "amson",
            "cloud computing",
            "optical network",
            "service plane",
            "internet",
            "grid computing",
            "photonics",
            "web pages",
            "resource management",
            "testing",
            "distributed computing",
            "meteorology",
            "servers",
            "service oriented architecture",
            "computer architecture",
            "adaptive systems"
        ],
        "authors": [
            {
                "name": "Zhen Li",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Dahai Han",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Xiuzhong Chen",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Yuefeng Ji",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Proceedings of SPIE - The International Society for Optical Engineering",
        "year": 2009
    },
    "X8LZC3e8": {
        "id": "X8LZC3e8",
        "title": "The research of cloud computing based on service plane over optical networks",
        "abstract": "A novel cloud computing architecture over optical networks is proposed based on the service plane. An experiment of resources dynamic co-schedule is deployed on our AMSON testbed and the result of it demonstrates the validity ofthe architecture we proposed. ©2009 Optical Society of America.",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Zhen Li",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Xiuzhong Chen",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Dahai Han",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Yuefeng Ji",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "2009 Asia Communications and Photonics Conference and Exhibition, ACP 2009",
        "year": 2009
    },
    "XGt3qONd": {
        "id": "XGt3qONd",
        "title": "A PCE-based fast reroute algorithm for multi-failures in multi-domain optical networks",
        "abstract": "A routing architecture based on PCE has been designed for the large, multi-layer and multi-domain optical networks, and a PCE-based fast reroute algorithm has been proposed for multi-failures in multi-domain optical networks. © 2009 OSA/ACP.",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Xuping Cao",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Yongli Zhao",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jian Liu",
                "org": "Hunan Environmental Protection Bureau(Hunan Environmental Protection Bureau),Changsha,China"
            },
            {
                "name": "Dahai Han",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "2009 Asia Communications and Photonics Conference and Exhibition, ACP 2009",
        "year": 2009
    },
    "CXLnNLww": {
        "id": "CXLnNLww",
        "title": "PCE-based service level agreement constraint routing strategy in multi-domain optical network",
        "abstract": "We developed a framework for constraint routing in multi-domain optical network which combines PCE with service plane. With the distributed routing computation characteristic of PCE and the adaptability of service plane for service attributes, the framework provides an optimal SLA-based constraint routing strategy. Experiment results verify our framework and strategy. © 2009 SPIE-OSA-IEEE.",
        "keywords": [
            "C",
            "Constraint",
            "E",
            "P",
            "Routing",
            "SLA",
            "SLA sub-TLV"
        ],
        "authors": [
            {
                "name": "Ying Chen",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Dahai Han",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Xiuzhong Chen",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Yongli Zhao",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Yuefeng Ji",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Proceedings of SPIE - The International Society for Optical Engineering",
        "year": 2009
    },
    "kLyJj9KK": {
        "id": "kLyJj9KK",
        "title": "A novel layer 1 virtual private network provisioning architecture in multi-domain optical networks",
        "abstract": "A novel multi-domain L1VPN provisioning architecture is proposed based on service plane of the adaptive multi-services provisioning platform. Moreover, the architecture we proposed was experimentally demonstrated in our AMSON testbed. ©2009 Optical Society of America.",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Ting Sun",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Dahai Han",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Xiuzhong Chen",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Feng Yuan",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "2009 Asia Communications and Photonics Conference and Exhibition, ACP 2009",
        "year": 2009
    },
    "bNsYcy0L": {
        "id": "bNsYcy0L",
        "title": "Capacity planning of WDM networks using cost-based ant colony algorithm",
        "abstract": "A cost-effective capacity planning method of WDM networks is proposed for increase of traffic load. An improved cost-based ant colony algorithm is presented from pheromone increase and update mechanisms to solve the planning problem. Simulation results show the applicability of our planning method.",
        "keywords": [
            "wavelength division multiplexing",
            "cost function",
            "routing",
            "ant colony algorithm",
            "explosives",
            "planning",
            "cost effectiveness",
            "switches"
        ],
        "authors": [
            {
                "name": "Pei Luo",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Shanguo Huang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Lin Lv",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Bin Li",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Communications and Photonics Conference and Exhibition",
        "year": 2009
    },
    "RDgetKFx": {
        "id": "RDgetKFx",
        "title": "Research on capacity planning of WDM networks using improved ant colony algorithm",
        "abstract": "A cost-effective capacity planning method of WDM networks is proposed for increase of traffic load. An improved costbased ant colony algorithm is presented from pheromone increase and update mechanisms to solve the planning problem. Simulation results show the applicability of our planning method.",
        "keywords": [
            "wavelength assignment",
            "ant colony algorithm",
            "wdm network planning",
            "routing",
            "routing and wavelength assignment",
            "capacity planning",
            "cost effectiveness",
            "photonics",
            "wavelength division multiplexing",
            "cost function",
            "communication networks"
        ],
        "authors": [
            {
                "name": "Pei Luo",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Shanguo Huang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Lin Lv",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Bin Li",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "ACP), 2009 Asia",
        "year": 2009
    },
    "fvTfAwSD": {
        "id": "fvTfAwSD",
        "title": "Adaptive routing and wavelength assignment algorithms for hierarchical architecture in ASON",
        "abstract": "The hierarchical routing and wavelength assignment problem in Automatic Switched Optical Network (ASON) is researched. Based on our analysis, three adaptive algorithms called MLLR (Multi-Layer Least Loaded Routing Algorithm), WMLCR (Wavelength-graph-based Multi-Layer Least Congestion Routing Algorithm) and BMR (Backtracking-based Multi-Layer Routing Algorithm) are proposed. A platform named AHORSP (ASON based hierarchical optimal routing & signaling platform) supporting our routing scheme is proposed and demonstrated. The simulation shows that the proposed algorithms can have comprehensive application on the basis of their convenience to be realized, low BP performance and acceptable operation time. ©2009 IEEE.",
        "keywords": [
            "ason",
            "fixed alternate routing",
            "hierarchical routing",
            "resource balancing",
            "routing and wavelength assignment",
            "adaptive routing",
            "routing",
            "bmr",
            "protocols",
            "algorithm design and analysis",
            "optical switches",
            "topology",
            "data mining",
            "approximation algorithms"
        ],
        "authors": [
            {
                "name": "Pei Luo",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Shanguo Huang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Bin Li",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Proceedings of 2009 IEEE International Conference on Network Infrastructure and Digital Content, IEEE IC-NIDC2009",
        "year": 2009
    },
    "qZutBKBZ": {
        "id": "qZutBKBZ",
        "title": "The design, implementation and performance analysis of transport-MPLS network",
        "abstract": "Transport multiple protocol label switching (transport-MPLS, T-MPLS) is one of networking schemes for packet transport network (PTN). It specifies a connection-oriented, packet-switched architecture for carrier class Ethernet. In order to evaluate the performance of T-MPLS network, we have to apply this technology to the real network topology with Internet-bound traffic (e.g., VoIP, P2P, Http). In this paper, we first design the functional architecture and interface of T-MPLS network. Then a novel simulation test bed based on 11-node topology of European Cost239 model is implemented. Most of protocols are realized and the characteristics of packet transport network are verified via numerical simulation.",
        "keywords": [
            "class-wfq",
            "real network topology",
            "t-mpls networking schemes",
            "11-node topology",
            "multiprotocol label switching",
            "packet transport network",
            "european cost239 model",
            "packet-switched architecture",
            "transport-mpls",
            "packet transport-mpls network performance analysis",
            "telecommunication network topology",
            "internet-bound traffic",
            "telecommunication traffic",
            "pseudo wire",
            "transport multiple protocol label switching",
            "carrier class ethernet",
            "data mining",
            "p2p",
            "bandwidth",
            "numerical simulation",
            "test bed",
            "network topology",
            "time division multiplexing"
        ],
        "authors": [
            {
                "name": "Chang Cao",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Yongjun Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Shanguo Huang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Beijing",
        "year": 2009
    },
    "tCzeTm2l": {
        "id": "tCzeTm2l",
        "title": "Clock synchronization in T-MPLS network via PTP (IEEE 1588 V2)",
        "abstract": "Clock synchronization is an essential problem faced by packet transport network. PTP (precise time protocol) can be used to solve this problem.Its feasibility has been verified by related literatures. In this paper, we use the OPNET simulation platform to further study the key factors affect the clocks' accuracy of packet-based synchronization schemes, e.g., queuing disciplines, network traffic load, whether low-pass filter is used or not, and deployment of the PTP enabled router. We intend to answer the question how much influence can each factor make to the clocks' synchronization performance.",
        "keywords": [
            "t-mpls",
            "ptp",
            "clock synchronization",
            "ieee 1588",
            "networks",
            "master slave",
            "time division multiplexing",
            "data mining",
            "jitter",
            "photonics",
            "physical layer",
            "synchronization",
            "low pass filter",
            "accuracy",
            "protocols"
        ],
        "authors": [
            {
                "name": "Rui Chen",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Yongjun Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Chang Cao",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Yongli Zhao",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Bin Li",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "ACP), 2009 Asia",
        "year": 2009
    },
    "dktDpSB4": {
        "id": "dktDpSB4",
        "title": "Clock synchronization in T-MPLS network via PTP (IEEE 1588 V2)",
        "abstract": "Clock synchronization is an essential problem faced by packet transport network. PTP (precise time protocol) can be used to solve this problem.Its feasibility has been verified by related literatures. In this paper, we use the OPNET simulation platform to further study the key factors affect the clocks' accuracy of packet-based synchronization schemes, e.g., queuing disciplines, number of nodes that PTP messages have passed, deployment of the PTP enabled router, and network traffic load. We intend to answer the question how much influence can each factor make to the clocks' synchronization performance. © 2009 OSA/ACP.",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Rui Chen",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Yongjun Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Chang Cao",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Yongli Zhao",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Bin Li",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "2009 Asia Communications and Photonics Conference and Exhibition, ACP 2009",
        "year": 2009
    },
    "Mna6WMF6": {
        "id": "Mna6WMF6",
        "title": "Energy efficient design based on the coordination of management and control in a multi-domain WSON",
        "abstract": "An energy efficiency scheme based on the coordination of management and control is proposed to reduce the power consumption in multi-domain WSON. Experiments are conducted on the energy efficient multi-domain WSON testbed (EEMWT) to assess the performance of the scheme. ©2010 IEEE.",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Lin Lv",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Shanguo Huang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Haotian Huang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Bingli Guo",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Chris I. Phillips",
                "org": "Queen Mary, University of London(^ University of London,Queen Mary University of London),London,United Kingdom"
            },
            {
                "name": "Yongjun Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "2010 Asia Communications and Photonics Conference and Exhibition, ACP 2010",
        "year": 2010
    },
    "KY7kcHgI": {
        "id": "KY7kcHgI",
        "title": "Fast path setup-oriented resource pre-configuration strategy in multi-granularity optical networks",
        "abstract": "To meet the requirements of multi-granularity optical networks for capability of switching at different granularities, a resource pre-configuration strategy is introduced into multi-granularity optical networks. By pre-configuring the resource of multi-granularity optical networks, the topology can be reconstructed with the number of direct routes increasing. The performance of routing and forwarding can be optimized. Numerical simulations show the connection establishing time of control plane could be significantly reduced by using resource pre-configuration strategy.",
        "keywords": [
            "Multi-granularity optical networks",
            "Resource pre-configuration",
            "Routing and wavelength assignment",
            "Topology"
        ],
        "authors": [
            {
                "name": "Yongli Zhao",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Beijing Youdian Daxue Xuebao/Journal of Beijing University of Posts and Telecommunications",
        "year": 2010
    },
    "F7GhXuDc": {
        "id": "F7GhXuDc",
        "title": "Design of an improved microstructure fibre for broadband dispersion compensation with low nonlinearity",
        "abstract": "A microstructure fibre for broadband dispersion compensation with low nonlinearity in a wide wavelength range centred at 1550 nm is designed. The effects of the number of air-hole rings, the air-hole diameters and the lattice pitch on both the dispersion property and nonlinear phenomenon are numerically described. The results indicate that the inner six air-hole rings have stronger impact on dispersion and nonlinearity. By adjusting the diameters of the fourth to sixth air-hole rings and the lattice pitch, the proposed microstructure fibre can compensate (to within 0.5%) the dispersion of 190 times of its length of a standard single-mode fibre with a low nonlinear coefficient over the entire 100 nm band centred at 1550 nm. © 2010 IOP Publishing Ltd.",
        "keywords": [
            "dispersion compensation",
            "fibre optics",
            "finite-difference beam propagation method",
            "microstructure fibre",
            "nonlinearity",
            "microstructures",
            "single mode fibre"
        ],
        "authors": [
            {
                "name": "Jiawei Han",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Shanglin Hou",
                "org": "Lanzhou University of Technology(Lanzhou University of Technology),Lanzhou,China"
            },
            {
                "name": "Daobin Wang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Journal of Optics",
        "year": 2010
    },
    "FU45H65y": {
        "id": "FU45H65y",
        "title": "Group-failure based cross-layer survivability research in intelligent optical networks",
        "abstract": "Different from general multi-failure, group-failure in cross-layer intelligent optical networks has the characteristic of cluster. Because multi-failure may occur due to single failure, it is more harmful for multi-failure than single failure. The original survivability with regards to multiple single failures is not suitable for group-failure based cross-layer survivability research. Group-failure based cross-layer survivability is eager to be solved in intelligent optical networks, and the corresponding key theory and technology are anxious to be proposed. This paper mainly focuses on the performance of cross-layer survivability based on group-failure in intelligent optical networks. Three topics are mainly paid attentions to, including the generation mechanism and model of group-failure in multi-layer optical networks, fast location mechanism for group-failure, and protection and recovery strategies applied to group-failure. At last, a PCE-based fast reroute algorithm (PFRR) is proposed and analyzed in the paper.",
        "keywords": [
            "survivability",
            "group failure",
            "crosslayer survivability research",
            "intelligent networks",
            "group-failure",
            "cross-layer",
            "intelligent optical networks",
            "pce based fast reroute algorithm",
            "optical communication",
            "crosslayer intelligent optical networks",
            "protocols",
            "topology",
            "network topology",
            "servers"
        ],
        "authors": [
            {
                "name": "Yongli Zhao",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Dahai Han",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Huibin Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Power System Technology",
        "year": 2010
    },
    "3nH7JJWw": {
        "id": "3nH7JJWw",
        "title": "Performance of PCE-based Fast Routing Strategy in Large-scale Multi-layer Multi-domain Optical Networks",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "yongli zhao",
                "org": ""
            },
            {
                "name": "shiyu zhao",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "dahai han",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2010
    },
    "tYLENAZU": {
        "id": "tYLENAZU",
        "title": "Application-oriented integrated control center (AICC) for heterogeneous optical networks",
        "abstract": "Various broad bandwidth services have being swallowing the bandwidth resource of optical networks, such as the data center application and cloud computation. There are still some challenges for future optical networks although the available bandwidth is increasing with the development of transmission technologies. The relationship between upper application layer and lower network resource layer is necessary to be researched further. In order to improve the efficiency of network resources and capability of service provisioning, heterogeneous optical networks resource can be abstracted as unified Application Programming Interfaces (APIs) which can be open to various upper applications through Application-oriented Integrated Control Center (AICC) proposed in the paper. A novel Openflow-based unified control architecture is proposed for the optimization of cross layer resources. Numeric results show good performance of AICC through simulation experiments. © 2011 SPIE-OSA-IEEE.",
        "keywords": [
            "AICC",
            "API",
            "Heterogeneous optical networks",
            "Openflow",
            "Unified control"
        ],
        "authors": [
            {
                "name": "Yongli Zhao",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Xuping Cao",
                "org": "Zte(ZTE Corporation,ZTE Corp.),Shenzhen,China"
            },
            {
                "name": "Dajiang Wang",
                "org": "Zte(ZTE Corporation,ZTE Corp.),Shenzhen,China"
            },
            {
                "name": "Koubo Wu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Yinxiang Cai",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Proceedings of SPIE - The International Society for Optical Engineering",
        "year": 2011
    },
    "MKD3soxt": {
        "id": "MKD3soxt",
        "title": "Analysis of blocking probability for OFDM-based variable bandwidth optical network",
        "abstract": "Orthogonal Frequency Division Multiplexing (OFDM) has recently been proposed as a modulation technique. For optical networks, because of its good spectral efficiency, flexibility, and tolerance to impairments, optical OFDM is much more flexible compared to traditional WDM systems, enabling elastic bandwidth transmissions, and optical networking is the future trend of development. In OFDM-based optical network the research of blocking rate has very important significance for network assessment. Current research for WDM network is basically based on a fixed bandwidth, in order to accommodate the future business and the fast-changing development of optical network, our study is based on variable bandwidth OFDM-based optical networks. We apply the mathematical analysis and theoretical derivation, based on the existing theory and algorithms, research blocking probability of the variable bandwidth of optical network, and then we will build a model for blocking probability. © 2011 SPIE-OSA-IEEE.",
        "keywords": [
            "blocking probability",
            "fixed routing",
            "OFDM",
            "variable-bandwidth"
        ],
        "authors": [
            {
                "name": "Lei Gong",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Yongli Zhao",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Xuefeng Lin",
                "org": "Zte(ZTE Corporation,ZTE Corp.),Shenzhen,China"
            },
            {
                "name": "Yuyao Wu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "2011 Asia Communications and Photonics Conference and Exhibition, ACP 2011",
        "year": 2011
    },
    "dV7YRkgJ": {
        "id": "dV7YRkgJ",
        "title": "Restoration scheme for multi-failures based on protection ring with dynamic weight in WDM networks",
        "abstract": "A novel restoration scheme for multi-failures based on protection ring with dynamic weight (PRDW) is proposed in this paper. This scheme effectively resolves the multi-failures which is in one service and the conflicts by restoration between services. PRDW use Dijkstra's algorithm to compute path and protection ring. These rings rely on protection weight which is dynamic, so that they can as much as possible to divide multi-failures to single ones. Meanwhile PRDW introduce independent protection weight to balance load, which effectively gets combat for resources less vicious. Simulation results show that PRDW works better than traditional schemes. © 2011 SPIE-OSA-IEEE.",
        "keywords": [
            "Multi-failures",
            "PCE",
            "Protection ring",
            "Protection weight",
            "WDM"
        ],
        "authors": [
            {
                "name": "Hai Huang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Yongli Zhao",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhanga",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Dajiang Wang",
                "org": "Zte(ZTE Corporation,ZTE Corp.),Shenzhen,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "2011 Asia Communications and Photonics Conference and Exhibition, ACP 2011",
        "year": 2011
    },
    "rkpMXDgY": {
        "id": "rkpMXDgY",
        "title": "A novel recovery algorithm for multi-link failures in spectrum-elastic optical path networks",
        "abstract": "In this paper, a novel survivable algorithm with dynamic load balancing shared-path protection is proposed, named DLBSPP algorithm, in spectrum-elastic optical path networks (SLICE). To tolerate multi-link failures in SLICE, traffic self-adaptive restoration (TSAR) mechanism is adopted to restore the traffic affected by the failures. Simulation results show that, compared with the conventional SPP algorithm, DLBSPP algorithm has lower blocking probability (BP), better spectrum utilization ratio (SUR) and higher failure restoration ratio (FRR). © 2011 SPIE-OSA-IEEE.",
        "keywords": [
            "Dynamical load balancing",
            "Multi-link failures restoration",
            "Recovery algorithm",
            "SLICE"
        ],
        "authors": [
            {
                "name": "Bowen Chen",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Yongli Zhao",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Chunhui Lv",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wei Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Yuan Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Shanguo Huang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "2011 Asia Communications and Photonics Conference and Exhibition, ACP 2011",
        "year": 2011
    },
    "yYkf8WkB": {
        "id": "yYkf8WkB",
        "title": "A novel PCE-based algorithm for P2MP inter-domain traffic engineering in optical networks",
        "abstract": "Point-to-Multipoint (P2MP) services in optical networks are more and more important for high-capacity applications. Steiner tree algorithms have been investigated to compute minimum-cost multicast tree. However, it is difficult to compute an optimal P2MP tree in multi-domain networks because of isolation of each domain. There are several algorithms based on Path Computation Element (PCE) for computing multi-domain Point-to-point path, but computing P2MP Traffic Engineering Label Switched Path (TE-LSP) in a multi-domain networks is still a challenge. In this paper, three PCE-based schemes for P2MP inter-domain LSP computation are compared in full splitting capability networks, and a novel Multi-Domain Minimum-cost Path Heuristic (MDMPH) algorithm is proposed. Simulation results proved that the MDMPH algorithm computes P2MP tree with less cost than the other three schemes. © 2011 SPIE-OSA-IEEE.",
        "keywords": [
            "full splitting capability",
            "inter-domain",
            "MDMPH",
            "multicast",
            "P2MP"
        ],
        "authors": [
            {
                "name": "Koubo Wu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Yongli Zhao",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Ziyan Yu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Dajiang Wang",
                "org": "Zte(ZTE Corporation,ZTE Corp.),Shenzhen,China"
            },
            {
                "name": "Xuping Cao",
                "org": "Zte(ZTE Corporation,ZTE Corp.),Shenzhen,China"
            }
        ],
        "venue": "2011 Asia Communications and Photonics Conference and Exhibition, ACP 2011",
        "year": 2011
    },
    "CFJV9k8U": {
        "id": "CFJV9k8U",
        "title": "Analysis of blocking probability for OFDM-based variable bandwidth optical network",
        "abstract": "Orthogonal Frequency Division Multiplexing (OFDM) has recently been proposed as a modulation technique. For optical networks, because of its good spectral efficiency, flexibility, and tolerance to impairments, optical OFDM is much more flexible compared to traditional WDM systems, enabling elastic bandwidth transmissions, and optical networking is the future trend of development. In OFDM-based optical network the research of blocking rate has very important significance for network assessment. Current research for WDM network is basically based on a fixed bandwidth, in order to accommodate the future business and the fast-changing development of optical network, our study is based on variable bandwidth OFDM-based optical networks. We apply the mathematical analysis and theoretical derivation, based on the existing theory and algorithms, research blocking probability of the variable bandwidth of optical network, and then we will build a model for blocking probability. © 2011 SPIE-OSA-IEEE.",
        "keywords": [
            "Blocking probability",
            "Fixed routing",
            "OFDM",
            "Variable-bandwidth"
        ],
        "authors": [
            {
                "name": "Lei Gong",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Yongli Zhao",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Xuefeng Lin",
                "org": "Zte(ZTE Corporation,ZTE Corp.),Shenzhen,China"
            },
            {
                "name": "Yuyao Wu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Optics InfoBase Conference Papers",
        "year": 2011
    },
    "eqeHRq8P": {
        "id": "eqeHRq8P",
        "title": "Dynamic weight protection ring apply to multi-failures in WDM optical networks",
        "abstract": "A novel restoration scheme for multi-failures based on dynamic weight protection ring (DWPR) is proposed in this paper, which resolves the simultaneous multi-failures and the conflicts by restoration between services effectively in Wavelength-Division-Multiplexing (WDM) optical mesh networks. DWPR use dijkstra algorithm to calculate route and protection ring. The protection ring is used to partition multi-failures, which can shorten the delay time by recovering link failures. Dynamic weight is introduced as load balancing, which reduces the conflict caused by restoring on common resource. Simulation results show that, compared with other scheme, DWPR has lower blocking rate, higher resource utilization and better multi-failures restoration rate.",
        "keywords": [
            "optical mesh networks",
            "dynamic protection weight",
            "dynamic weight protection ring",
            "wdm optical networks",
            "protection ring",
            "wavelength division multiplexing",
            "delay time",
            "wdm",
            "dijkstra algorithm",
            "link failures",
            "restoration",
            "multi-failures",
            "telecommunication network routing",
            "multi-failure restoration",
            "load balancing",
            "resource utilization",
            "load balance",
            "mesh network"
        ],
        "authors": [
            {
                "name": "Hai Huang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Linna Xia",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Yongli Zhao",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Information Photonics and Optical Communications",
        "year": 2011
    },
    "1BRWvvsc": {
        "id": "1BRWvvsc",
        "title": "Analysis of blocking probability for OFDM-based variable bandwidth optical network",
        "abstract": "Orthogonal Frequency Division Multiplexing (OFDM) has recently been proposed as a modulation technique. For optical networks, because of its good spectral efficiency, flexibility, and tolerance to impairments, optical OFDM is much more flexible compared to traditional WDM systems, enabling elastic bandwidth transmissions, and optical networking is the future trend of development. In OFDM-based optical network the research of blocking rate has very important significance for network assessment. Current research for WDM network is basically based on a fixed bandwidth, in order to accommodate the future business and the fast-changing development of optical network, our study is based on variable bandwidth OFDM-based optical networks. We apply the mathematical analysis and theoretical derivation, based on the existing theory and algorithms, research blocking probability of the variable bandwidth of optical network, and then we will build a model for blocking probability. © 2011 SPIE-OSA-IEEE.",
        "keywords": [
            "blocking probability",
            "fixed routing",
            "ofdm",
            "variable-bandwidth",
            "orthogonal frequency division multiplexing",
            "erbium",
            "spectral efficiency",
            "modulation",
            "networks",
            "business",
            "mathematics",
            "mathematical analysis",
            "wavelength division multiplexing",
            "algorithms"
        ],
        "authors": [
            {
                "name": "Lei Gong",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Yongli Zhao",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Xuefeng Lin",
                "org": "Zte(ZTE Corporation,ZTE Corp.),Shenzhen,China"
            },
            {
                "name": "Yuyao Wu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Proceedings of SPIE - The International Society for Optical Engineering",
        "year": 2011
    },
    "KBdf7beD": {
        "id": "KBdf7beD",
        "title": "An enhanced approach of inter-domain path computation in hierarchical PCE-based GMPLS multi-region networks",
        "abstract": "An integrated hierarchical PCE model is proposed to relieve the path selection policy constraint by the parent PCE in the hierarchical PCE (H-PCE) framework. The parent and child PCEs are unified by routing at a higher level in this new model, where each PCE maintains the summarized information of all the other domains apart from its interior link states in the Traffic Engineering Database (TED). This article puts forward a new procedure named Source-driven Hierarchical PCE-based Computation (SHPC) to compute shortest inter-domain paths in this new model, which provides a better approach to the solution of routing problems in PCE-based GMPLS multi-region networks. Numeric results show that SHPC does not ensure the best effectiveness of wavelength utilization but it achieves the lowest blocking probability in the IP-over-DWDM multi-domain environment under the scheme of routing with distributed wavelength assignment (R+DWA), which has been investigated and validated in the Dual Routing Engine (DRE) experimental platform.",
        "keywords": [
            "wavelength utilization",
            "ip networks",
            "brpc",
            "shpc",
            "multi-domain",
            "multiprotocol label switching",
            "ip-over-dwdm multidomain environment",
            "wavelength division multiplexing",
            "wavelength assignment",
            "blocking probability",
            "distributed wavelength assignment",
            "path selection policy constraint",
            "network routing problems",
            "inter-domain path computation approach",
            "dual routing engine experimental platform",
            "gmpls multiregion networks",
            "hierarchical pce",
            "interior link states",
            "traffic engineering database",
            "source-driven hierarchical pce-based computation",
            "telecommunication traffic",
            "telecommunication network routing",
            "integrated hierarchical pce model",
            "probability",
            "engines",
            "availability",
            "topology",
            "computer architecture",
            "routing",
            "computational modeling",
            "computer model",
            "accuracy"
        ],
        "authors": [
            {
                "name": "Yuan Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Yongli Zhao",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Yixia Mao",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Shengwei Meng",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Di Wu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Broadband Network and Multimedia Technology",
        "year": 2011
    },
    "3UZjuI0r": {
        "id": "3UZjuI0r",
        "title": "A Collision-aware Backward Recursive PCE-based Computation Algorithm in multi-domain optical networks",
        "abstract": "The traditional approach for inter-domain Traffic Engineering Label Switching Path (TE-LSP) computation like BRPC could provide a shortest inter-domain constrained TE-LSP, but under wavelength continuity constraint, it couldn't guarantee the success of the resources reservation for the shortest path. In this paper, a Collision-aware Backward Recursive PCE-based Computation Algorithm (CA-BRPC) in multi-domain optical networks under wavelength continuity constraint is proposed, which is implemented based on Hierarchical PCE (H-PCE) architecture, could provide an optimal inter-domain TE-LSP and avoid resources reservation conflict. Numeric results show that the CA-BRPC could reduce the blocking probability of entire network.",
        "keywords": [
            "collision-aware",
            "multi-domain",
            "traffic engineering label switching path",
            "optical fibre networks",
            "wavelength continuity constraint",
            "ca-brpc",
            "collision-aware backward recursive pce",
            "telecommunication computing",
            "h-pce",
            "recursive estimation",
            "multidomain optical networks",
            "hierarchical pce",
            "shortest path",
            "networks",
            "engineering"
        ],
        "authors": [
            {
                "name": "Jianchao Xing",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Yongli Zhao",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Xuping Cao",
                "org": "Zte(ZTE Corporation,ZTE Corp.),Shenzhen,China"
            },
            {
                "name": "Dajiang Wang",
                "org": "Zte(ZTE Corporation,ZTE Corp.),Shenzhen,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Shanghai",
        "year": 2011
    },
    "LJWH93vw": {
        "id": "LJWH93vw",
        "title": "A Collision-aware Backward Recursive PCE-based Computation Algorithm in multi-domain optical networks",
        "abstract": "The traditional approach for inter-domain Traffic Engineering Label Switching Path (TE-LSP) computation like BRPC could provide a shortest inter-domain constrained TE-LSP, but under wavelength continuity constraint, it couldn't guarantee the success of the resources reservation for the shortest path. In this paper, a Collision-aware Backward Recursive PCE-based Computation Algorithm (CA-BRPC) in multi-domain optical networks under wavelength continuity constraint is proposed, which is implemented based on Hierarchical PCE (H-PCE) architecture, could provide an optimal inter-domain TE-LSP and avoid resources reservation conflict. Numeric results show that the CA-BRPC could reduce the blocking probability of entire network. © 2011 SPIE-OSA-IEEE.",
        "keywords": [
            "CA-BRPC",
            "collision-aware",
            "H-PCE",
            "Multi-domain"
        ],
        "authors": [
            {
                "name": "Jianchao Xing",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Yongli Zhao",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Xuping Cao",
                "org": "Zte(ZTE Corporation,ZTE Corp.),Shenzhen,China"
            },
            {
                "name": "Dajiang Wang",
                "org": "Zte(ZTE Corporation,ZTE Corp.),Shenzhen,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "2011 Asia Communications and Photonics Conference and Exhibition, ACP 2011",
        "year": 2011
    },
    "0uG2Yo39": {
        "id": "0uG2Yo39",
        "title": "A collision-aware backward recursive PCE-based computation algorithm in multi-domain optical networks",
        "abstract": "The traditional approach for inter-domain Traffic Engineering Label Switching Path (TE-LSP) computation like BRPC could provide a shortest inter-domain constrained TE-LSP, but under wavelength continuity constraint, it couldn't guarantee the success of the resources reservation for the shortest path. In this paper, a Collision-aware Backward Recursive PCE-based Computation Algorithm (CA-BRPC) in multi-domain optical networks under wavelength continuity constraint is proposed, which is implemented based on Hierarchical PCE (H-PCE) architecture, could provide an optimal inter-domain TE-LSP and avoid resources reservation conflict. Numeric results show that the CA-BRPC could reduce the blocking probability of entire network. © 2011 SPIE-OSA-IEEE.",
        "keywords": [
            "CA-BRPC",
            "Collision-aware",
            "H-PCE",
            "Multi-domain"
        ],
        "authors": [
            {
                "name": "Jianchao Xing",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Yongli Zhao",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Xuping Cao",
                "org": "Zte(ZTE Corporation,ZTE Corp.),Shenzhen,China"
            },
            {
                "name": "Dajiang Wang",
                "org": "Zte(ZTE Corporation,ZTE Corp.),Shenzhen,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Optics InfoBase Conference Papers",
        "year": 2011
    },
    "rhMFEOZW": {
        "id": "rhMFEOZW",
        "title": "Contenionless ROADM architecture and extention for control plane in elastic optical path network",
        "abstract": "In this paper, we propose a colorless, directionless and contentionless (C/D/C) ROADM architecture using bandwidth variable carriers select switches (BV-WSS) for elastic optical network and illustrate various advantages offered by it. We also discuss some extensions for current control plane of ASON framework. © 2011 SPIE-OSA-IEEE.",
        "keywords": [
            "BV-WSS",
            "contentionless",
            "control plane",
            "elastic optical path network",
            "Optical OFDM",
            "ROADM"
        ],
        "authors": [
            {
                "name": "Weiguo Ju",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Shanguo Huang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Xin Li",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Bingli Guo",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Dajiang Wang",
                "org": "Zte(ZTE Corporation,ZTE Corp.),Shenzhen,China"
            },
            {
                "name": "Yongqi He",
                "org": "Peking University(Peking University),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "2011 Asia Communications and Photonics Conference and Exhibition, ACP 2011",
        "year": 2011
    },
    "1Fp7bKC7": {
        "id": "1Fp7bKC7",
        "title": "TE link dormant mode used in GMPLS optical transport networks for energy saving",
        "abstract": "This paper evaluates power efficiency of TE link dormant mode in optical transport network, considering daily traffic variability and GMPLS protocol. The proposed TE link dormant mode tries to let data links comprised the TE link transfer into the dormant state according to several selection criteria considering either the power consumption parameter of each link and their positioning in the network topology. The total energy saving is 35% on the energy efficient WSON test bed.",
        "keywords": [
            "optical transport networks",
            "multiprotocol label switching",
            "power consumption",
            "energy saving",
            "dormant mode",
            "optical fibre networks",
            "traffic engineering computing",
            "network topology",
            "wson",
            "te link dormant mode",
            "telecommunication network topology",
            "telecommunication computing",
            "gmpls",
            "traffic variability",
            "te link",
            "telecommunication traffic",
            "energy efficient",
            "networks",
            "wavelength division multiplexing",
            "power efficiency",
            "optical transport network",
            "test bed"
        ],
        "authors": [
            {
                "name": "Xin Li",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Shanguo Huang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Bingli Guo",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Shanghai",
        "year": 2011
    },
    "eiNe1iFL": {
        "id": "eiNe1iFL",
        "title": "TE link dormant mode used in GMPLS optical transport networks for energy saving",
        "abstract": "This paper evaluates power efficiency of TE link dormant mode in optical transport network, considering daily traffic variability and GMPLS protocol. The proposed TE link dormant mode tries to let data links comprised the TE link transfer into the dormant state according to several selection criteria considering either the power consumption parameter of each link and their positioning in the network topology. The total energy saving is 35% on the energy efficient WSON test bed. © 2011 SPIE-OSA-IEEE.",
        "keywords": [
            "Dormant Mode",
            "Energy Saving",
            "GMPLS",
            "TE link"
        ],
        "authors": [
            {
                "name": "Xin Li",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Shanguo Huang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Bingli Guo",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "2011 Asia Communications and Photonics Conference and Exhibition, ACP 2011",
        "year": 2011
    },
    "EDdxrw59": {
        "id": "EDdxrw59",
        "title": "TE link dormant mode used in GMPLS optical transport networks for energy saving",
        "abstract": "This paper evaluates power efficiency of TE link dormant mode in optical transport network, considering daily traffic variability and GMPLS protocol. The proposed TE link dormant mode tries to let data links comprised the TE link transfer into the dormant state according to several selection criteria considering either the power consumption parameter of each link and their positioning in the network topology. The total energy saving is 35% on the energy efficient WSON test bed. © 2011 SPIE-OSA-IEEE.",
        "keywords": [
            "Dormant mode",
            "Energy saving",
            "GMPLS",
            "TE link"
        ],
        "authors": [
            {
                "name": "Xin Li",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Shanguo Huang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Bingli Guo",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Optics InfoBase Conference Papers",
        "year": 2011
    },
    "SOhLcNYm": {
        "id": "SOhLcNYm",
        "title": "Dynamic Survivable Mapping in IP Over WDM Network",
        "abstract": "As the survivable mapping is critical in IP-over-wavelength-division-multiplexing (WDM) network to guarantee the restorability of IP layer, provisioning survivability in network with dynamic traffic is essential. However, survivable mapping problem for dynamic traffic shows more complexity than that for static traffic: 1) How to guarantee a survivable mapping since the lightpath is established and released dynamically; 2) how to make a balance between the cost of maintaining the survivable mapping and network utilization efficiency; 3) what kind of algorithm could be employed as an efficient online algorithm with acceptable computing complexity and scalability. In this paper, two schemes, dynamic routing and logical topology remapping, are proposed to keep a survivable mapping from logical topology to physical topology in dynamic traffic scenario. In addition, two different cutset-searching methods are presented in order to support the proposed online survivable mapping algorithm. At the end, a series of experiments employing regular networks and some special topologies with different connectivity have been carried out in order to evaluate the efficiency and scalability of our approach, in terms of the blocking probability, resource utilization, critical link holding time, and the restoration rate for random single failures. Generally, our results show that this new approach offers great degree of survivability for IP layer, but with acceptable resource cost and complexity.",
        "keywords": [
            "Topology",
            "Network topology",
            "IP networks",
            "Heuristic algorithms",
            "Routing",
            "WDM networks"
        ],
        "authors": [
            {
                "name": "Bingli Guo",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Shanguo Huang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Pei Luo",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Haotian Huang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Lightwave Technology, Journal of",
        "year": 2011
    },
    "V7JJJn9S": {
        "id": "V7JJJn9S",
        "title": "Centralized and distributed routing and spectrum assignment schemes for bandwidth-variable optical networks",
        "abstract": "Flexible bandwidth networking has recently been proposed as a spectrally efficient networking technology that effectively supports dynamically varying traffic demands [1]. This networking technology provides an opportunity to maximize spectral efficiency for each of many arbitrary bandwidth channels generated using one of many possible modulation formats [2]. Path Computation Element (PCE) is first introduced for dynamic routing and spectrum assignment problem in elastic optical network. We proposed three centralized and distributed routing and spectrum assignment solutions. They are Centralized Routing and Distributed Spectrum Assignment (CR+DSA), Centralized Routing and Centralized Spectrum Assignment (CR+CSA) and Distributed Routing and Distributed Spectrum Assignment (DR+DSA). The two centralized proposals both own PCE in its architecture. The performance of three proposed centralized and distributed routing and spectrum assignment solutions have been analyzed and compared. For the experimental evaluation, the performance of Centralized Routing and Centralized Spectrum Assignment is the most adaptable RSA strategy for the whole bandwidth-variable optical networks with dynamic traffic. © 2011 SPIE-OSA-IEEE.",
        "keywords": [
            "Centralized",
            "Distributed",
            "Routing and spectrum assignment",
            "SLICE"
        ],
        "authors": [
            {
                "name": "Jingjing Wang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Yongli Zhao",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Yuyao Wu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Dajiang Wang",
                "org": "Zte(ZTE Corporation,ZTE Corp.),Shenzhen,China"
            },
            {
                "name": "Xuping Cao",
                "org": "Zte(ZTE Corporation,ZTE Corp.),Shenzhen,China"
            }
        ],
        "venue": "2011 Asia Communications and Photonics Conference and Exhibition, ACP 2011",
        "year": 2011
    },
    "31SaDvdP": {
        "id": "31SaDvdP",
        "title": "Structural and wavelength dependence of mode power distribution for a broadband dispersion compensating microstructured fiber",
        "abstract": "Approximate empirical analysis of mode power distribution (MPD) carried by the fundamental mode is newly investigated based on a broadband dispersion compensating microstructured fiber (MF). The fraction of modal power in the core region, η, is defined with the help of extending the applicability of well-established classical optical fiber theories to MFs. In doing so, the influences of structural parameters and wavelength on MPD characteristics of the fundamental mode are systematically analyzed in detail based on simple physically consistent concepts of conventional fibers. As a result, it is shown that for the optimum MF design in Ref. [11] as a multimode fiber, when the number of guiding modes increases, the mode power ratio of the fundamental mode constantly increases from 69.4%; in addition, we find that as wavelength increases within 1.2-1.6 μm, mode power confinement ability of the fundamental mode is lessened for single-mode propagation, whereas for multimode propagation it becomes enhanced. © 2011 Elsevier GmbH.",
        "keywords": [
            "dispersion compensating",
            "microstructured fiber",
            "mode power distribution"
        ],
        "authors": [
            {
                "name": "Jiawei Han",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jien Song",
                "org": "Huaxin Consulting Co., Ltd.(Huaxin Consulting Co Ltd,Huaxin Consulting Co., Ltd,Huaxin Consulting Co., Ltd.),Hangzhou,China"
            },
            {
                "name": "Yun Xia",
                "org": "Huaxin Consulting Co., Ltd.(Huaxin Consulting Co Ltd,Huaxin Consulting Co., Ltd,Huaxin Consulting Co., Ltd.),Hangzhou,China"
            },
            {
                "name": "Shanglin Hou",
                "org": "Lanzhou University of Technology(Lanzhou University of Technology),Lanzhou,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Optik",
        "year": 2012
    },
    "yKoaqIDV": {
        "id": "yKoaqIDV",
        "title": "Traffic grooming in Flexible Bandwidth Optical Networks",
        "abstract": "Three novel traffic grooming schemes are proposed in Flexible Bandwidth Optical Networks. Simulations show that considering both link and spectrum resource efficiency, Improved Shortest Path Scheme can achieve better performance compared with the others.",
        "keywords": [
            "optical fibre networks",
            "traffic grooming",
            "shortest path scheme",
            "optical links",
            "flexible bandwidth optical networks",
            "optical link",
            "telecommunication traffic",
            "spectrum resource efficiency"
        ],
        "authors": [
            {
                "name": "Yibo Jia",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Yongli Zhao",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Ting Zhou",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Xiaosong Yu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Hui Yang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Communications and Photonics Conference",
        "year": 2012
    },
    "1Niwaw91": {
        "id": "1Niwaw91",
        "title": "Dynamic spectral defragmentation based on path connectivity in flexible bandwidth networks",
        "abstract": "A novel dynamic defragmentation algorithm MPC (Maximize Path Connectivity) is proposed based on the notion of Path Connectivity. Simulation results show that the proposed algorithm reduces blocking probability significantly and achieves higher profitability. © 2012 Optical Society of America.",
        "keywords": [
            "wavelength division multiplexing"
        ],
        "authors": [
            {
                "name": "Ying Wang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Yongli Zhao",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jiawei Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhao",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Xinbo Wang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "European Conference on Optical Communication, ECOC",
        "year": 2012
    },
    "BSh9cg9U": {
        "id": "BSh9cg9U",
        "title": "A novel method to evaluate clustering algorithms for hierarchical optical networks",
        "abstract": "The routing issues in multi-layer and multi-domain optical networks have drawn much attention in current research. With the introduction of the path computation element, routes can be calculated more efficiently in multi-domain optical networks. However, the optimal degree of routing approach in multi-layer and multi-domain optical networks is also determined by the clustering algorithms deployed for construction of hierarchical networks. Therefore, it is important to investigate the way to evaluate the impact of the clustering algorithm on the routing approach (e.g., blocking probability) in optical networks with dynamic traffic, which has not been studied sufficiently. In this paper, a novel method to describe and evaluate the clustered structures generated by different clustering algorithms for hierarchical optical networks is proposed. This method deploys a novel evaluation metric that represents blocking probability of clustered optical networks, so it can be used as guidelines for designing clustered structures. Besides theoretical analysis, simulations are carried out on different network topologies and clustered types to validate the effectiveness of the method presented.",
        "keywords": [
            "Optical networks",
            "Hierarchical networks",
            "Wavelength division multiplexing",
            "Clustering algorithm",
            "Routing algorithm",
            "Blocking probability"
        ],
        "authors": [
            {
                "name": "Shanguo Huang",
                "org": "State Key Laboratory of Information Photonics and Optical Communications, Beijing University of Posts and Telecommunications, Beijing, People's Republic of China 100876"
            },
            {
                "name": "Weihua Lian",
                "org": "State Key Laboratory of Information Photonics and Optical Communications, Beijing University of Posts and Telecommunications, Beijing, People's Republic of China 100876"
            },
            {
                "name": "Xian Zhang",
                "org": "Department of Electronic Engineering, Queen Mary, University of London, London, UK E1 4NS"
            },
            {
                "name": "Bingli Guo",
                "org": "State Key Laboratory of Information Photonics and Optical Communications, Beijing University of Posts and Telecommunications, Beijing, People's Republic of China 100876"
            },
            {
                "name": "Pei Luo",
                "org": "Research Institute of Highway Ministry of Transport, Beijing, People's Republic of China 100088"
            },
            {
                "name": "Jie Zhang",
                "org": "State Key Laboratory of Information Photonics and Optical Communications, Beijing University of Posts and Telecommunications, Beijing, People's Republic of China 100876"
            },
            {
                "name": "Wanyi Gu",
                "org": "State Key Laboratory of Information Photonics and Optical Communications, Beijing University of Posts and Telecommunications, Beijing, People's Republic of China 100876"
            }
        ],
        "venue": "Photonic Network Communications",
        "year": 2012
    },
    "te7w1Bgj": {
        "id": "te7w1Bgj",
        "title": "Pre-configured polyhedron (p-poly) based protection structure against multi-link failures in optical networks",
        "abstract": "In this paper, we propose a novel protection scheme based on pre-configured polyhedron (p-poly) structure against multi-link failures in high capacity and large scale optical transport networks. P-poly structure has higher capacity efficiency than the existing p-cycle protection structure even though we can design p-cycle based networks for multi-link failures scenario. We provide a theoretical underpinning for the application of p-poly structure in providing protection against multi-link failures. Two greedy algorithms and two ant colony optimization algorithms are respectively proposed for constructing p-poly structure in static and dynamic networks. Numerical results show that the logic redundancy of p-poly based networks is slightly higher than the lower bound on logic redundancy of link-restorable networks but much lower than that of p-cycles based protection structure under dual-link and three-link failures. © 2012 IEEE.",
        "keywords": [
            "aco",
            "greedy algorithms",
            "multi-link failures",
            "network redundancy",
            "network survivability"
        ],
        "authors": [
            {
                "name": "Shanguo Huang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Xin Li",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Yongli Zhao",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "CHINACOM",
        "year": 2012
    },
    "5bLjuS6W": {
        "id": "5bLjuS6W",
        "title": "Spectrum consecutiveness based routing and spectrum allocation in flexible bandwidth networks",
        "abstract": "In flexible bandwidth optical networks, the dynamic lightpath setup and teardown inevitably lead to spectrum fragmentation which blocks the new connections. In order to effectively allocate the spectrum along a better route, a notion of available spectrum consecutiveness is introduced and three dynamic routing and spectrum assignment (RSA) algorithms are proposed in this letter accordingly. The novel algorithms retain the spectrum consecutiveness as much as possible when establishing a lightpath and reduce the spectrum fragmentation. Simulation results indicate that our proposed spectrum consecutiveness based RSA algorithms achieve lower blocking probability and higher adaptability to more line rates mixture. © 2012 Chinese Optics Letter.",
        "keywords": [],
        "authors": [
            {
                "name": "Ying Wang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Yongli Zhao",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Junyan Liu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Chinese Optics Letters",
        "year": 2012
    },
    "5yBusp9q": {
        "id": "5yBusp9q",
        "title": "Dynamic adaptive spectrum defragmentation scheme in elastic optical path networks",
        "abstract": "We propose two novel adaptive spectrum defragmentation algorithms in elastic optical networks by properly rerouting existing connections based on the evaluation of current network status, and numerical evaluation shown to be resource efficient. © 2012 IEEE.",
        "keywords": [
            "decision support systems",
            "adaptive optics",
            "routing",
            "bandwidth",
            "topology"
        ],
        "authors": [
            {
                "name": "Weiguo Ju",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Shanguo Huang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Zhenzhen Xu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Technical Digest - 2012 17th Opto-Electronics and Communications Conference, OECC 2012",
        "year": 2012
    },
    "gWvIdhZh": {
        "id": "gWvIdhZh",
        "title": "A novel shared-path protection algorithm with correlated risk against multiple failures in flexible bandwidth optical networks",
        "abstract": "In this paper, to decrease the traffic loss caused by multiple link failures, we consider the correlated risk among different connection requests when both the primary and backup paths are routed and assigned spectrum. Therefore, a novel shared-path protection algorithm is developed, named shared-path protection algorithm with correlated risk (SPP-CR), in flexible bandwidth optical networks. Based on the correlated risk, the routing can be diverse and the sharing in backup spectral resource will be restricted by SPP-CR algorithm, then the dropped traffic caused by simultaneous multiple failures between primary and backup path can be efficiently decreased. Simulation results show that, SPP-CR algorithm (i) achieves the higher successful service ratio (SSR) than traditional shared-path protection (SPP), shared-path protection with dynamic load balancing (SPP-DLB) and dedicated path protection (DPP); (ii) makes a better tradeoff in blocking probability, protection ratio (PR), average frequency slots consumed (AFSC) and redundancy ratio (RR) than SPP, SPP-DLB and DPP algorithms. © 2012 Elsevier Inc. All rights reserved.",
        "keywords": [
            "Flexible bandwidth optical networks",
            "Survivability",
            "Multiple failures",
            "Correlated risk protection"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Chunhui Lv",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Yongli Zhao",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Bowen Chen",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Xin Li",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Shanguo Huang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Optical Fiber Technology",
        "year": 2012
    },
    "gRVARsgm": {
        "id": "gRVARsgm",
        "title": "Best fit decreasing based defragmentation algorithm in semi-dynamic elastic optical path networks",
        "abstract": "We propose a novel spectrum defragmentation algorithm in semi-dynamic elastic optical networks by introducing best fit decreasing strategy, numerical evaluation shows that the improvement of the blocking performance and small amount number of interrupted connections are achieved simultaneously. © 2012 OSA.",
        "keywords": [],
        "authors": [
            {
                "name": "Jia Wang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Shanguo Huang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Weiguo Ju",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Yongqi He",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Hongxiang Wang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Asia Communications and Photonics Conference, ACP",
        "year": 2012
    },
    "k0zSwN4Z": {
        "id": "k0zSwN4Z",
        "title": "A novel multi-fault localization mechanism in PCE-based multi-domain large capacity optical transport networks",
        "abstract": "A stateful PCE-based multi-link failure localization mechanism using fuzzy fault set is implemented in multi-domain large capacity optical networks. The novel localization mechanism has high scalability, speed and success rate compared with extended LVM protocol.",
        "keywords": [
            "protocols",
            "optical fibre networks",
            "fuzzy fault set",
            "multi-fault localization mechanism",
            "multi-domain large capacity optical networks",
            "pce-based multi-domain large capacity optical transport networks",
            "pce-based multi-link failure localization mechanism",
            "lvm protocol",
            "topology",
            "network topology"
        ],
        "authors": [
            {
                "name": "Jingran Luo",
                "org": "Beijing University of Posts and Telecommunitions(Beijing University of Posts and Telecommunitions,Beijing Univ. of Posts and Tele.),,China"
            },
            {
                "name": "Shanguo Huang",
                "org": "Beijing University of Posts and Telecommunitions(Beijing University of Posts and Telecommunitions,Beijing Univ. of Posts and Tele.),,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunitions(Beijing University of Posts and Telecommunitions,Beijing Univ. of Posts and Tele.),,China"
            },
            {
                "name": "Xin Li",
                "org": "Beijing University of Posts and Telecommunitions(Beijing University of Posts and Telecommunitions,Beijing Univ. of Posts and Tele.),,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunitions(Beijing University of Posts and Telecommunitions,Beijing Univ. of Posts and Tele.),,China"
            }
        ],
        "venue": "Optical Fiber Communication Conference and Exposition",
        "year": 2012
    },
    "F2v8y0f7": {
        "id": "F2v8y0f7",
        "title": "Routing and spectrum assignment by means of ant colony optimization in flexible bandwidth networks",
        "abstract": "We propose a dynamic ACO-based routing and spectrum assignment algorithm in the flexible bandwidth optical networks. Simulation results show that the novel strategy achieves a lower blocking probability with high adaptability to the traffic rate variation.",
        "keywords": [
            "ant colony optimisation",
            "flexible-bandwidth optical networks",
            "optical fibre networks",
            "blocking probability",
            "ant colony optimization",
            "traffic rate variation",
            "telecommunication network routing",
            "dynamic aco-based routing-spectrum assignment algorithm",
            "bandwidth",
            "routing"
        ],
        "authors": [
            {
                "name": "Ying Wang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Yongli Zhao",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jingjing Wang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Optical Fiber Communication Conference and Exposition",
        "year": 2012
    },
    "CYSrS6qH": {
        "id": "CYSrS6qH",
        "title": "Analysis of blocking probability For OFDM-based bandwidth-variable optical networks",
        "abstract": "Compared with the rigid and coarse granularity of Wavelength Division Multiplexing (WDM) networks, Orthogonal Frequency Division Multiplexing (OFDM)-based bandwidth-variable optical networks have the advantages of good spectral efficiency, flexibility, and tolerance to impairments, and can support the service with the bandwidth requirement of higher or lower than one wavelength. Blocking probability is one of the most important parameters for circuit-based optical networks performance evaluation, and of significance for the network planning. Using mathematical analysis and theoretical derivation, an analytical method for computing blocking probability is proposed for OFDM-based bandwidth-variable optical networks. A blocking probability model based on the wavelength decomposition approach (WDA) is built accordingly, and analyzed through the analytical and simulation results. Numeric results show that the blocking probability computed with our methodology matches closely with the blocking probability obtained through simulations for different traffic loads, which proves the correctness of our proposed blocking probability model.",
        "keywords": [
            "traffic load",
            "wavelength decomposition approach",
            "wavelength division multiplexing",
            "optical fibre networks",
            "blocking probability",
            "ofdm modulation",
            "orthogonal frequency division multiplexing",
            "bandwidth allocation",
            "bandwidth-variable",
            "wda",
            "network planning",
            "optical networks",
            "circuit-based optical network",
            "ofdm",
            "telecommunication traffic",
            "bandwidth-variable optical network",
            "spectral efficiency",
            "wdm network",
            "probability"
        ],
        "authors": [
            {
                "name": "Yongli Zhao",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jiawei Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "CHINACOM",
        "year": 2012
    },
    "ovC6fNBW": {
        "id": "ovC6fNBW",
        "title": "Multi-link failure restoration with dynamic load balancing in spectrum-elastic optical path networks",
        "abstract": "In this paper, we investigate network performance of multi-link failure restoration in spectrum-elastic optical path networks (SLICE). To efficiently restore traffic under multi-link failures, a novel survivable algorithm, named dynamic load balancing shared-path protection (DLBSPP), is proposed to compute primary and link-disjoint shared backup paths. The DLBSPP algorithm employs first fit (FF) and random fit (RF) schemes to search and assign the available spectrum resource. Traffic-aware restoration (TAR) mechanism is adopted in the DLBSPP algorithm to compute new routes for carrying the traffic affected by the multi-link failures and then the multi-link failures can be efficiently restored. Simulation results show that, compared with the conventional shared-path protection (SPP) algorithm, the DLBSPP algorithm achieves lower blocking probability (BP), better spectrum utilization ratio (SUR), more reasonable average hop (AH) and higher failure restoration ratio (FRR). Thus, the proposed DLBSPP algorithm has much higher spectrum efficiency and much better survivability than SPP algorithm. © 2011 Elsevier Inc. All rights reserved.",
        "keywords": [
            "SLICE",
            "Survivability",
            "Multi-link failure restoration",
            "Dynamical load balancing shared protection"
        ],
        "authors": [
            {
                "name": "Bowen Chen",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Yongli Zhao",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Chunhui Lv",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wei Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Shanguo Huang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Xian Zhang",
                "org": "Queen Mary, University of London(^ University of London,Queen Mary University of London),London,United Kingdom"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Optical Fiber Technology",
        "year": 2012
    },
    "pGmrfjTL": {
        "id": "pGmrfjTL",
        "title": "A Novel Protection Scheme Based on Hamiltonian Cycle in the Elastic Optical Networks",
        "abstract": "This paper proposes a protection mechanism utilizing Hamiltonian cycle based on slots. Numerical simulation shows the proposed scheme achieve higher level of survivability for the traffic in the Elastic Optical Networks.",
        "keywords": [
            "network survivability",
            "higher level",
            "all-optical networks",
            "hamiltonian cycle",
            "optical fibre networks",
            "numerical analysis",
            "novel protection scheme",
            "protection and restoration",
            "proposed scheme",
            "numerical simulation",
            "elastic optical networks",
            "protection mechanism"
        ],
        "authors": [
            {
                "name": "Tianbao Lan",
                "org": ""
            },
            {
                "name": "Shanguo Huang",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Wanyi Gu",
                "org": ""
            }
        ],
        "venue": "Instrumentation, Measurement, Computer, Communication and Control",
        "year": 2012
    },
    "NvNGrVS6": {
        "id": "NvNGrVS6",
        "title": "Minimized spectral resource consumption with rescaled failure probability constraint in flexible bandwidth optical networks",
        "abstract": "We propose an ILP model and an efficient rescaled failure-probability-aware algorithm (RFPA) to minimize spectral resource consumption. Simulation results show that, compared to a traditional algorithm, both ILP model and RFPA achieve higher spectrum efficiency. OFC/NFOEC Technical Digest © 2013 OSA.",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Bowen Chen",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Yongli Zhao",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Haining Chen",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Shanguo Huang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jason Jue",
                "org": "University of Texas at Dallas(University of Texas at Dallas,University of Texas),Richardson,United States"
            }
        ],
        "venue": "Optical Fiber Communication Conference and Exposition and the National Fiber Optic Engineers Conference",
        "year": 2013
    },
    "opQRhMyL": {
        "id": "opQRhMyL",
        "title": "Minimum Spectrum Block Consumption for Shared-Path Protection with Joint Failure Probability in Flexible Bandwidth Optical Networks",
        "abstract": "We propose a minimum-free-spectrum-block-consumption algorithm (MFSB) for shared-path protection with joint failure probability requirements in flexible bandwidth optical networks. Compared with conventional algorithms, MFSB efficiently decreases the spectrum block consumption and achieves higher spectrum utilization. © 2013 OSA.",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "A. Bowen Chen",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "A. Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "A. Yongli Zhao",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "A. Jinyan Liu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "A. Shanguo Huang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "A. Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jason Jue",
                "org": "University of Texas at Dallas(University of Texas at Dallas,University of Texas),Richardson,United States"
            }
        ],
        "venue": "2013 Optical Fiber Communication Conference and Exposition and the National Fiber Optic Engineers Conference, OFC/NFOEC 2013",
        "year": 2013
    },
    "vXUcwrj1": {
        "id": "vXUcwrj1",
        "title": "Fragment fusion degree based dynamic defragmentation in flexible grid optical networks",
        "abstract": "Flexible grid optical networks have been attracting much attention for their high spectrum efficiency (SE) and flexibility compared to the rigid grid WDM networks. As well known, the networks suffer from the problem of spectrum fragmentation under dynamic traffic. In this paper, we propose a new concept called 'fragment fusion degree (FFD)' to assess the level of spectrum fragmentation in flexible grid optical networks, which is calculated based on the availability of the spectrum fragments among neighboring links. Two FFD based dynamic defragmentation algorithms are presented to fuse the spectrum fragments among neighboring links. Simulation results show that the proposed defragmentation algorithms reduce blocking probability significantly and achieve high profitability. © 2013 Elsevier GmbH.",
        "keywords": [
            "flexible grid optical networks",
            "fragment fusion degree (ffd)",
            "spectrum defragmentation"
        ],
        "authors": [
            {
                "name": "Weiguo Ju",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Shanguo Huang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Bingli Guo",
                "org": "Peking University(Peking University),Beijing,China"
            },
            {
                "name": "Zhenzhen Xu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Yongqi He",
                "org": "Peking University(Peking University),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            }
        ],
        "venue": "Optik",
        "year": 2013
    },
    "hzNuFlfT": {
        "id": "hzNuFlfT",
        "title": "Pre-configured multi-dimensional protection (p-MDP) structure against multi-failures in high-degree node based optical networks",
        "abstract": "In this paper, a novel protection structure i.e. pre-configured multi-dimensional protection (p-MDP) structure is proposed against simultaneous m-link failures in high capacity and large scale optical transport networks (OTNs). The principles of p-MDP are proved, which shows that there are m+1 internally node-disjoint paths between any two nodes on p-MDP. It can provide 100% recovery to any m-link failures, and use less protection resource than p-Cycle. Heuristic algorithms of construction, protection and fast restoration on p-MDP are proposed in static optical transport networks. Numerical results show that, p-MDP can improve the survivability of optical networks, and it has lower redundancy but a bit longer recovery time than p-Cycle in dealing with the same number of simultaneous multi-link failures. © 2013 IEEE.",
        "keywords": [
            "heuristic algorithm",
            "multi-link failures",
            "network survivability",
            "protection structure"
        ],
        "authors": [
            {
                "name": "Chen Ma",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Yongli Zhao",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Jian Yuan",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Shanguo Huang",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Wanyi Gu",
                "org": "Beijing University of Posts and Telecommunications(Beijing University of Posts and Telecommunications,Beijing Univ. of Posts and Telecom.),Beijing,China"
            },
            {
                "name": "Yang Wang",
                "org": "China Electric Power Research Institute(China Electric Power Research Institute,Electric Power Research Inst),Beijing,China"
            },
            {
                "name": "Huixia Ding",
                "org": "China Electric Power Research Institute(China Electric Power Research Institute,Electric Power Research Inst),Beijing,China"
            },
            {
                "name": "Lifeng Lu",
                "org": "China Electric Power Research Institute(China Electric Power Research Institute,Electric Power Research Inst),Beijing,China"
            }
        ],
        "venue": "2013 8th International ICST Conference on Communications and Networking in China, CHINACOM 2013 - Proceedings",
        "year": 2013
    },
    "4OpBKRkA": {
        "id": "4OpBKRkA",
        "title": "Microbial control and biotechnology research on Bacillus thuringiensis in China.",
        "abstract": "The current status of production and application of biopesticides for pest control in China is briefly reviewed, with a focus on research advances in microbial control with Bacillus thuringiensis (Bt). These have led to improvements in Bt production, exploitation of Bt gene resources, and development of engineered Bt insecticides and transgenic Bt crops that have expanded host ranges and increased efficacy against target pests. Both conventional and biotechnology approaches need to be employed to achieve further progress in discovery, production technology, formulation processing, development of quality standards and recommended use patterns.",
        "keywords": [
            "biotechnology",
            "microbial control",
            "bacillus thuringiensis",
            "biopesticide",
            "bt crops",
            "host range",
            "process development",
            "quality standard",
            "pest control"
        ],
        "authors": [
            {
                "name": "Da-Fang Huang",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": "State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100094, China"
            },
            {
                "name": "Fu-Ping Song",
                "org": "State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100094, China"
            },
            {
                "name": "Zhi-Hong Lang",
                "org": "Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China"
            }
        ],
        "venue": "Journal of invertebrate pathology",
        "year": 2007
    },
    "8phS4QNd": {
        "id": "8phS4QNd",
        "title": "Identification and Distribution of Bacillus thuringiensis Isolates from Primeval Forests in Yunnan and Hainan Provinces and Northeast Region of China",
        "abstract": "Ninety-two Bacillus thuringiensis isolates were screened from 683 soil samples collected from tropical and semitropical primeval forests in Yunnan and Hainan provinces of China. Several shapes of crystals,including bipyramidal,square,ovoid,spherical,and amorphous,were observed in the B. thuringiensis isolates. Twenty-six pairs of primers were used to identify 31 holotype cry genes at primary rank of the B. thuringiensis cry gene nomenclature system. The cry gene-types of 92 B. thuringiensis isolates and 33 B. thuringiensis isolates screened from Northeast region of China were identified by PCR-RFLP and SDS-PAGE methods. Fifty-eight isolates harbored cry1 genes,32 isolates cry2 genes,12 isolates cry8 genes,3 isolates cry9 genes,12 isolates cry11 genes,and 13 isolates cry30 genes. Of the tested isolates,42 produced no reaction product with 26 pairs of primers and also exhibited no toxicity against 8 insect species tested. The isolate Z2-34 harbored a novel cry30 gene,exhibited insecticidal activity against Aedes albopictus of Dipterans. The accession number of the novel genes in this study is AY916046. Isolation and identification of B. thuringiensis and cry gene are important for investigating the diversity of B. thuringiensis resources and cloning new cry gene.",
        "keywords": [
            "Aedes albopictus",
            "Bacillus thuringiensis",
            "cry gene",
            "PCR-RFLP"
        ],
        "authors": [
            {
                "name": "Xu-dong SU",
                "org": "Agricultural University of Hebei, Baoding 071001, P.R.China"
            },
            {
                "name": "Chang-long SHU",
                "org": "State Key Laboratory of Biology for Plant Diseases and Insect Pests/Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100094, P.R.China"
            },
            {
                "name": "Jie ZHANG",
                "org": "State Key Laboratory of Biology for Plant Diseases and Insect Pests/Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100094, P.R.China"
            },
            {
                "name": "Da-fang HUANG",
                "org": "Institute of Biotechnology Research, Chinese Academy of Agricultural Sciences, Beijing 100081, P.R.China"
            },
            {
                "name": "Jian-xin TAN",
                "org": "Agricultural University of Hebei, Baoding 071001, P.R.China"
            },
            {
                "name": "Fu-ping SONG",
                "org": ""
            }
        ],
        "venue": "中国农业科学(英文版)",
        "year": 2007
    },
    "SNH5M047": {
        "id": "SNH5M047",
        "title": "Isolation of transposon mutants and characterization of genes involved in biofilm formation by Pseudomonas fluorescens TC222.",
        "abstract": "Biofilm formation mutants are often found to have defective or altered motility. The motility phenotype was exploited to identify\n Pseudomonas fluorescens biofilm formation mutants. Fourteen motility mutants were obtained from P. fluorescens isolate TC222 and eight stable mutants were studied further. The eight transposon insertion mutants showed altered ability\n to form biofilm compared with the parent. Five Tn5-inserted genes from these mutants were cloned and sequenced. Genetic analysis\n showed that two insertions were located in genes affecting multiple cell surface characteristics, including lipopolysaccharide\n (rfbD) and polar flagella (fliR). Three genes encoding for a putative Mig-14 family protein (epsB), a probable bacteriophage signal peptide protein (bspA) and a soluble pyridine nucleotide transhydrogenase (pyrA) were reported for the first time to be involved in biofilm formation. Complementation experiments of rfbD and epsB genes proved that biofilm formation of the corresponding mutants could be restored. Further semi-quantitative reverse transcription-PCR\n analysis showed that both rfbD and epsB can express their transcripts much higher in the complemented strains than that in wild-type strains. The transcripts of\n both genes in their mutants could not be detected.",
        "keywords": [
            "complementation",
            "tn5 mutagenesis",
            "biofilm formation",
            "semi-quantitative reverse transcription-pcr analysis",
            "pseudomonas fluorescens",
            "genetic analysis",
            "reverse transcription pcr",
            "wild type",
            "signal peptide",
            "nucleotides"
        ],
        "authors": [
            {
                "name": "Hongjuan Nian",
                "org": "Chinese Academy of Agricultural Sciences(Chinese Academy of Agricultural Sciences),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Chinese Academy of Agricultural Sciences(Chinese Academy of Agricultural Sciences),Beijing,China"
            },
            {
                "name": "Fuping Song",
                "org": "Chinese Academy of Agricultural Sciences(Chinese Academy of Agricultural Sciences),Beijing,China"
            },
            {
                "name": "Liqiang Fan",
                "org": "Chinese Academy of Agricultural Sciences(Chinese Academy of Agricultural Sciences),Beijing,China"
            },
            {
                "name": "Dafang Huang",
                "org": "Chinese Academy of Agricultural Sciences(Chinese Academy of Agricultural Sciences),Beijing,China"
            }
        ],
        "venue": "Archives of microbiology",
        "year": 2007
    },
    "plGBpwAF": {
        "id": "plGBpwAF",
        "title": "Effect of transgenic cotton with cry1Ac gene on intestinal bacterial community of apis mellifera ligustica",
        "abstract": "The effect of transgenic cotton SGK321 with cry1Ac gene on bacterial community structures in honeybee (Apis mellifera ligustica) intestines was studied by denaturing gradient gel electrophoresis (DGGE) based on sequencing of 16S rDNA.The honeybees were fed with the transgenic cotton pollens,non-transgenic cotton pollen and foreign DNA of high concentration for seven days,respectively.The intestinal bacterial diversity of each treatment was analyzed by DGGE and the possibility of a horizontal gene transfer was detected by polymerase chain reaction (PCR).The DGGE profile showed that the number of bands of all treatments ranged between 11.3～15.0 and Shannon's index between 0.87～1.05.The similarity (Dice) coefficient among the treatments ranged from 68.3% to 84.7%.These indices showed that different diets could not change the bacterial diversity in the honeybee intestines.At the same time,gene transfer was not detected.It was concluded that the transgenic cotton had no detrimental effects on the microbial diversity in honeybee intestines in short period of time.Fig 2,Tab 3,Ref 22",
        "keywords": [
            "DGGE",
            "Gene horizontal transfer",
            "Honeybee",
            "Intestinal microorganism",
            "Transgenic cotton"
        ],
        "authors": [
            {
                "name": "Weiyu Jiang",
                "org": "Chinese Academy of Agricultural Sciences(Chinese Academy of Agricultural Sciences),Beijing,China"
            },
            {
                "name": "Pingli Dai",
                "org": "Chinese Academy of Agricultural Sciences(Chinese Academy of Agricultural Sciences),Beijing,China"
            },
            {
                "name": "Yongjun Zhang",
                "org": "Chinese Academy of Agricultural Sciences(Chinese Academy of Agricultural Sciences),Beijing,China"
            },
            {
                "name": "Ting Zhou",
                "org": "Chinese Academy of Agricultural Sciences(Chinese Academy of Agricultural Sciences),Beijing,China"
            },
            {
                "name": "Yi Lin",
                "org": "Huaqiao University(Huaqiao University),Quanzhou,China"
            },
            {
                "name": "Changlong Shu",
                "org": "Chinese Academy of Agricultural Sciences(Chinese Academy of Agricultural Sciences),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Chinese Academy of Agricultural Sciences(Chinese Academy of Agricultural Sciences),Beijing,China"
            }
        ],
        "venue": "Chinese Journal of Applied and Environmental Biology",
        "year": 2010
    },
    "LjF09Cj6": {
        "id": "LjF09Cj6",
        "title": "High-efficiency regeneration of peanut (Arachis hypogaea L.) plants from leaf discs",
        "abstract": "A high-efficiency regeneration system for peanut plants was established. The regeneration frequency of leaf discs reached 40.9% on Murashige and Skoog medium supplemented with 0.5 mg l -1 naphthylacetic acid and 0.5 mg l -1 thidiazuron. The regenerated shoots elongated, developed roots and produced seeds. This procedure was highly efficient and is feasible for the genetic transformation of peanuts. © 2011 Academic Journals.",
        "keywords": [
            "high efficiency",
            "peanut",
            "regeneration"
        ],
        "authors": [
            {
                "name": "Lili Geng",
                "org": "Chinese Academy of Agricultural Sciences(Chinese Academy of Agricultural Sciences),Beijing,China"
            },
            {
                "name": "Lihong Niu",
                "org": "Chinese Academy of Agricultural Sciences(Chinese Academy of Agricultural Sciences),Beijing,China"
            },
            {
                "name": "Changlong Shu",
                "org": "Chinese Academy of Agricultural Sciences(Chinese Academy of Agricultural Sciences),Beijing,China"
            },
            {
                "name": "Fuping Song",
                "org": "Chinese Academy of Agricultural Sciences(Chinese Academy of Agricultural Sciences),Beijing,China"
            },
            {
                "name": "Dafang Huang",
                "org": "Chinese Academy of Agricultural Sciences(Chinese Academy of Agricultural Sciences),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Chinese Academy of Agricultural Sciences(Chinese Academy of Agricultural Sciences),Beijing,China"
            }
        ],
        "venue": "African Journal of Biotechnology",
        "year": 2011
    },
    "Fm22InQA": {
        "id": "Fm22InQA",
        "title": "Identification of the minimal active fragment of the Cry1Ah toxin.",
        "abstract": "cry1Ah1, a novel holo-type gene cloned from Bacillus thuringiensis strain BT-8, encoded a protein exhibiting strong insecticidal activity against lepidopteran insects. To identify the minimal active fragment of the Cry1Ah toxin, 9 pairs of primers were designed to generate different PCR products. Seven PCR products were amplified by different primers using the cry1Ah1 gene as a template and cloned into a pET-21b vector. These positive clones were separately transformed into Escherichia coli. Insecticidal activity against 2nd-instar larvae of Plutella xylostella was performed using the leaf-dip bioassay: the minimal active fragment of the Cry1Ah toxin was located between amino acid residues 50I and 639E.",
        "keywords": [
            "Bacillus thuringiensis",
            "Cry1Ah",
            "Toxicity",
            "Minimal active fragment",
            "Plutella xylostella"
        ],
        "authors": [
            {
                "name": "Jing Xue",
                "org": "State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, 100193 People’s Republic of China"
            },
            {
                "name": "Zishan Zhou",
                "org": "State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, 100193 People’s Republic of China"
            },
            {
                "name": "Fuping Song",
                "org": "State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, 100193 People’s Republic of China"
            },
            {
                "name": "Changlong Shu",
                "org": "State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, 100193 People’s Republic of China"
            },
            {
                "name": "Dafang Huang",
                "org": "Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing, 100081 People’s Republic of China"
            },
            {
                "name": "Jie Zhang",
                "org": "State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, 100193 People’s Republic of China"
            }
        ],
        "venue": "Biotechnology letters",
        "year": 2011
    },
    "HtoCLi2r": {
        "id": "HtoCLi2r",
        "title": "An improved PCR-restriction fragment length polymorphism (RFLP) method for the identification of cry1-type genes.",
        "abstract": "The cry1-type genes of Bacillus thuringiensis represent the largest cry gene family, which contains 50 distinct holotypes. It is becoming more and more difficult to identify cry1-type genes using current methods because of the increasing number of cry1-type genes. In the present study, an improved PCR-restriction fragment length polymorphism (PCR-RFLP) method which can distinguish 41 holotypes of cry1-type genes was developed. This improved method was used to identify cry1-type genes in 20 B. thuringiensis strains that are toxic to lepidoptera. The results showed that the improved method can efficiently identify single and clustered cry1-type genes and can be used to evaluate cry1-type genes in novel strain collections of B. thuringiensis. Among the detected cry1-type genes, we identified four novel genes, cry1Ai, cry1Bb, cry1Ja, and cry1La. The bioassay results from the expressed products of the four novel cry genes showed that Cry1Ai2, Cry1Bb2, and Cry1Ja2 were highly toxic against Plutella xylostella, whereas Cry1La2 exhibited no activity. Moreover, Cry1Ai2 had good lethal activity against Ostrinia furnacalis, Hyphantria cunea, Chilo suppressalis, and Bombyx mori larvae and considerable weight loss activity against Helicoverpa armigera.",
        "keywords": [],
        "authors": [
            {
                "name": "Changlong Shu",
                "org": "Chinese Academy of Agricultural Sciences(Chinese Academy of Agricultural Sciences),Beijing,China"
            },
            {
                "name": "Dongming Liu",
                "org": "Chinese Academy of Agricultural Sciences(Chinese Academy of Agricultural Sciences),Beijing,China"
            },
            {
                "name": "Zishan Zhou",
                "org": "Chinese Academy of Agricultural Sciences(Chinese Academy of Agricultural Sciences),Beijing,China"
            },
            {
                "name": "Jilin Cai",
                "org": "Chinese Academy of Agricultural Sciences(Chinese Academy of Agricultural Sciences),Beijing,China"
            },
            {
                "name": "Qi Peng",
                "org": "Chinese Academy of Agricultural Sciences(Chinese Academy of Agricultural Sciences),Beijing,China"
            },
            {
                "name": "Jiguo Gao",
                "org": "Northeast Agricultural University(Northeast Agricultural University),Harbin,China"
            },
            {
                "name": "Fuping Song",
                "org": "Chinese Academy of Agricultural Sciences(Chinese Academy of Agricultural Sciences),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Chinese Academy of Agricultural Sciences(Chinese Academy of Agricultural Sciences),Beijing,China"
            }
        ],
        "venue": "Applied and environmental microbiology",
        "year": 2013
    },
    "3CWxF7KW": {
        "id": "3CWxF7KW",
        "title": "The influence of Bt-transgenic maize pollen on the bacterial diversity in the midgut of Apis mellifera ligustica",
        "abstract": "Honeybees are subjected to direct contact with transgenic maize pollen due to their feeding activities on pollen. The potential side effects of transgenic cry1Ah-maize pollen on the midgut bacteria of the larvae and worker bees of Apis mellifera ligustica were investigated through denaturing gradient gel electrophoresis under both laboratory and field conditions. Newly emerged bees were fed transgenic cry1Ah-maize pollen, normal maize pollen, linear cry1Ah gene DNA, supercoiled plasmid DNA, and sugar syrup under the laboratory conditions. The results showed that there were no significant differences in the midgut bacterial community composition among the five treatments. No significant effects were observed in the midgut communities between larvae and adult honeybees fed transgenic cry1Ah-maize pollen and non-transgenic maize pollen in the field trials. © 2012 INRA, DIB and Springer-Verlag France.",
        "keywords": [
            "apis mellifera",
            "denaturing gradient gel electrophoresis",
            "intestinal community",
            "transgenic maize"
        ],
        "authors": [
            {
                "name": "Lili Geng",
                "org": "Chinese Academy of Agricultural Sciences(Chinese Academy of Agricultural Sciences),Beijing,China"
            },
            {
                "name": "Hongjuan Cui",
                "org": "Chinese Academy of Agricultural Sciences(Chinese Academy of Agricultural Sciences),Beijing,China"
            },
            {
                "name": "Pingli Dai",
                "org": "Ministry of Agriculture of the People's Republic of China(Ministry of Agriculture),Beijing,China"
            },
            {
                "name": "Zhihong Lang",
                "org": "Chinese Academy of Agricultural Sciences(Chinese Academy of Agricultural Sciences),Beijing,China"
            },
            {
                "name": "Changlong Shu",
                "org": "Chinese Academy of Agricultural Sciences(Chinese Academy of Agricultural Sciences),Beijing,China"
            },
            {
                "name": "Ting Zhou",
                "org": "Ministry of Agriculture of the People's Republic of China(Ministry of Agriculture),Beijing,China"
            },
            {
                "name": "Fuping Song",
                "org": "Chinese Academy of Agricultural Sciences(Chinese Academy of Agricultural Sciences),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Chinese Academy of Agricultural Sciences(Chinese Academy of Agricultural Sciences),Beijing,China"
            }
        ],
        "venue": "Apidologie",
        "year": 2013
    },
    "GqPovY6T": {
        "id": "GqPovY6T",
        "title": "Chloroplast-targeted expression of the codon-optimized truncated cry1Ah gene in transgenic tobacco confers a high level of protection against insects.",
        "abstract": "The study of insect-resistant transgenic tobacco provides a good foundation for the further application of the cry1Ah gene in other important crops. To improve transgene expression levels and insect resistance, the coding sequence of the novel Bacillus thuringiensis insecticidal gene cry1Ah (truncated cry1Ah) was modified according to the codon bias of the plant by increasing its GC content from the original 37 % to 48, 55, and 63 % (designated m1-cry1Ah, m2-cry1Ah, and m3-cry1Ah, respectively). In addition, the m3-cry1Ah gene was linked with a transit peptide sequence for chloroplast-targeted expression (designated ctp-m3-cry1Ah). Four plant expression vectors were constructed harboring m1-cry1Ah, m2-cry1Ah, m3-cry1Ah, or ctp-m3-cry1Ah. A total of 23 transgenic tobacco lines were produced with the four constructs by Agrobacterium tumefaciens-mediated transformation. PCR, Southern hybridization, quantitative RT-PCR and ELISA indicated that the cry1Ah gene was not only integrated into the tobacco genome, but was also successfully expressed at the mRNA and protein levels. The Cry1Ah protein level in ctp-m3-cry1Ah plants reached 4.42 μg/g fresh weight, which was a 2- to 10-fold increase over the levels observed in m1-cry1Ah, m2-cry1Ah, and m3-cry1Ah plants and resulted in the highest resistance to Helicoverpa armigera based on bioassays. Our results demonstrated that combining the codon optimization of cry1Ah gene with the targeting of Cry1Ah protein to the chloroplasts conferred a high level of protection against insects. The results of our experiments in tobacco, an important model system, provide a good foundation for enhancing the insecticidal efficacy of staple crops.",
        "keywords": [
            "truncated cry1ah gene",
            "codon optimization",
            "transgenic tobacco",
            "chloroplast targeting",
            "insect resistance"
        ],
        "authors": [
            {
                "name": "Xiuying Li",
                "org": "Northeast Agricultural University(Northeast Agricultural University),Harbin,China"
            },
            {
                "name": "Shengyan Li",
                "org": "Chinese Academy of Agricultural Sciences(Chinese Academy of Agricultural Sciences),Beijing,China"
            },
            {
                "name": "Zhihong Lang",
                "org": "Chinese Academy of Agricultural Sciences(Chinese Academy of Agricultural Sciences),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Chinese Academy of Agricultural Sciences(Chinese Academy of Agricultural Sciences),Beijing,China"
            },
            {
                "name": "Li Zhu",
                "org": "Chinese Academy of Agricultural Sciences(Chinese Academy of Agricultural Sciences),Beijing,China"
            },
            {
                "name": "Dafang Huang",
                "org": "Northeast Agricultural University(Northeast Agricultural University),Harbin,China"
            }
        ],
        "venue": "Plant cell reports",
        "year": 2013
    },
    "ARhdNTBY": {
        "id": "ARhdNTBY",
        "title": "Determination of the Contents of Total Saponins of Panax natoginseng in the Effective Fraction of Guanxin Danshen Tablet",
        "abstract": "Objective To establish the determination method of total saponins of Panax notoginseng in Guanxin Danshen tablet by UV.Methods UV,the detection wavelength was at 548 nm.Results The linear range was in the range of 0.0202～0.202mg.The average recovery was 97.38 %,and RSD was 1.10%(n=6).Conclusion The method is simple,highly accurate,and it can be used for quality control of Guanxin Danshen tablet.",
        "keywords": [
            "Guanxin Danshen tablet",
            "Total saponins of Panax notoginseng",
            "Spectrophotometry"
        ],
        "authors": [
            {
                "name": "WEI Hui-zhen",
                "org": "Jiangxi University of Chinese Traditional Medicine,Jiangxi Nanchang ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Jiangxi University of Chinese Traditional Medicine,Jiangxi Nanchang ,China"
            },
            {
                "name": "ZHANG Hong-hong",
                "org": "The National Pharmaceutical Engineering Center for Solid Preparation in Chinese Herbal Medicine,Jiangxi Nanchang ,China"
            },
            {
                "name": "WANG Yue-sheng",
                "org": "The National Pharmaceutical Engineering Center for Solid Preparation in Chinese Herbal Medicine,Jiangxi Nanchang ,China"
            },
            {
                "name": "FANG Hai-hong",
                "org": "Jiangxi University of Chinese Traditional Medicine,Jiangxi Nanchang ,China"
            },
            {
                "name": "RAO Yi",
                "org": "Jiangxi University of Chinese Traditional Medicine,Jiangxi Nanchang ,China"
            },
            {
                "name": "LI Xin-nan",
                "org": "Jiangxi University of Chinese Traditional Medicine,Jiangxi Nanchang ,China"
            }
        ],
        "venue": "Lishizhen Medicine and Materia Medica Research",
        "year": 2008
    },
    "zAEU8565": {
        "id": "zAEU8565",
        "title": "Study of Chromatographic Behavior of Oxymatrine,Sophoridine and Matrine by Ion Exchange Chromatography",
        "abstract": "In this paper,the effects of pH,concentration of buffer and triethylamine in mobile phase on chromatographic behavior of oxymatrine,sophoridine and matrine were studied by using ion exchange chromatography and their mechanisms were discussed.The results showed that pH of the mobile phase had great effect on chromatographic behavior of alkaloid and pKa of alkaloid could be used to guide the choice of the pH of the mobile phase.When the pH of mobile phase closed to the pKa of alkaloids,the value of capacity factor of three kinds alkaloids were decreased rapidly.Within the range of 20-100 mmol/L buffer concentration,the increase of buffer concentration would result in the decrease of the retention value and increase of the column efficiency.The results also showed that concentration of triethylamine in mobile phase had certain impact on the retention value,symmetry and column efficiency of alkaloids,that because the addition of triethylamine in mobile phase could masked free silicon-hydroxyl on the column.Under the appropriate conditions,the method was further used in the separation and determination of 3 alkaloids in radix sophorae flavescentis with satisfactory results.",
        "keywords": [
            "chromatographic behavior",
            "ion exchange chromatography",
            "matrine",
            "oxymatrine",
            "sophoridine"
        ],
        "authors": [
            {
                "name": "FANG Hai-hong",
                "org": "College of Pharmaceutical Sciences,Jiangxi University of Traditional Chinese Medicine,Nanchang ,China"
            },
            {
                "name": "YAN Yan",
                "org": "College of Pharmaceutical Sciences,Jiangxi University of Traditional Chinese Medicine,Nanchang ,China"
            },
            {
                "name": "ZHU Sheng-sheng",
                "org": "College of Pharmaceutical Sciences,Jiangxi University of Traditional Chinese Medicine,Nanchang ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "College of Pharmaceutical Sciences,Jiangxi University of Traditional Chinese Medicine,Nanchang ,China"
            },
            {
                "name": "WEI Hui-zhen",
                "org": "College of Pharmaceutical Sciences,Jiangxi University of Traditional Chinese Medicine,Nanchang ,China;The National Pharmaceutical Engineering Center%%#NPEC%%# for Solid Preparation in Chinese Herbal Medicine,Nanchang ,China"
            },
            {
                "name": "RAO Yi",
                "org": "College of Pharmaceutical Sciences,Jiangxi University of Traditional Chinese Medicine,Nanchang ,China;The National Pharmaceutical Engineering Center%%#NPEC%%# for Solid Preparation in Chinese Herbal Medicine,Nanchang ,China"
            }
        ],
        "venue": "Journal of Instrumental Analysis",
        "year": 2008
    },
    "XxrrwmwA": {
        "id": "XxrrwmwA",
        "title": "Determination of peoniflorin,naringin,aurantiamarin,neohesperidin,and ammonium glycyrrhizinate in Sini Powder by HPLC-\"internal standard\" multi-control method",
        "abstract": "Objective To establish a new quality evaluation method for Chinese compound medicine,using the \"internal standard\" in Sini Powder reference substance and to calculate multi-components simul- taneously. Methods Relative correction factors (RCF) of naringin,aurantiamarin,neohesperidin,ammo-nium glycyrrhizinate,and a characteristic component peoniflorin as marker,were calcalated in the chro-matographic conditions for the determination of Sini Powder as a research model. The content of peoni-florin was determined by external standard method,and those of naringin,aurantiamarin,neohesperidin,and ammonium glycyrrhizinnate were calculated by RCF compared with peoniflorin. The accuracy of the new method was evaluated by comparing the calculated contents with the determined contents. Results The linear response ranges of peoniflorin,naringin,aurantiamarin,neohesperidin,and ammonium gly-cyrrhizinate were 0.281 2-1.6870μg (r=0.999 6),0.5700-3.4200μg (r=0.999 4),0.0502- 0.3012 μg (r=0.999 9),0.0502-0.3012 μg (r=0.999 9),0.5230-3.138 0μg (r=0.999 9),0.3310-1.9860μg (r = 0. 9998). Conclusion For the first time,\"internal standard\" multi-control method is adopted in HPLC determination for five reference substances in Sini Powder. The assay demon-strates that the method is feasible and avalable for the quality control of Sini Powder and it is to be a new quality evaluation pattern for Chinese compound medicines.",
        "keywords": [
            "HPLC",
            "\"internal standard\" multi-control method",
            "aurantiamarin",
            "peoniflorin",
            "Sini Powder",
            "ammonium glycyrrhi-zinate",
            "naringin",
            "neohesperidin"
        ],
        "authors": [
            {
                "name": "WANG Yue-sheng",
                "org": "The National Pharmaceutical Engineering Center for Solid Preparation in Chinese Herbal Medicine,Nanchang ,China"
            },
            {
                "name": "WEI Hui-zhen",
                "org": "The National Pharmaceutical Engineering Center for Solid Preparation in Chinese Herbal Medicine,Nanchang ,China"
            },
            {
                "name": "WU You-gen",
                "org": " Jiangxi University of Traditional Chinese Medicine,Nanchang ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": " Jiangxi University of Traditional Chinese Medicine,Nanchang ,China"
            },
            {
                "name": "FANG Hai-hong",
                "org": " Jiangxi University of Traditional Chinese Medicine,Nanchang ,China"
            },
            {
                "name": "CHEN Yin-fang",
                "org": " Jiangxi University of Traditional Chinese Medicine,Nanchang ,China"
            }
        ],
        "venue": "Chinese Traditional and Herbal Drugs",
        "year": 2008
    },
    "OQXNFJu9": {
        "id": "OQXNFJu9",
        "title": "Application of uncertainty to Traditional Chinese Medicine",
        "abstract": "The application of uncertainty in the field of traditional Chinese medicine(TCM)in recent years are reviewed,problems existing in the wider application of this technology are explored and prospects of its application in TCM are discussed.",
        "keywords": [
            "Uncertainty",
            "progess",
            "traditional Chinese medicine"
        ],
        "authors": [
            {
                "name": "RAO Yi",
                "org": "The National Pharmaceutical Engineering Center for Solid Preparation in Chinese Herbal Medicine,Nanchang "
            },
            {
                "name": "WEI Hui-zhen",
                "org": "The National Pharmaceutical Engineering Center for Solid Preparation in Chinese Herbal Medicine,Nanchang "
            },
            {
                "name": "ZHANG Jie",
                "org": "Jiangxi University of Chinese Traditional Medicine,Nanchang ,China"
            },
            {
                "name": "LI Xin-Nan",
                "org": "Jiangxi University of Chinese Traditional Medicine,Nanchang ,China"
            },
            {
                "name": "WANG Yue-Sheng",
                "org": "The National Pharmaceutical Engineering Center for Solid Preparation in Chinese Herbal Medicine,Nanchang "
            }
        ],
        "venue": "Journal of Jiangxi University of Traditional Chinese Medicine",
        "year": 2008
    },
    "IHLGXarN": {
        "id": "IHLGXarN",
        "title": "Study of the combination of sodium valproate and arsenous trioxide on HL-60 cells",
        "abstract": "Objective: To study the growth inhibition and apoptosis of HL-60 cells affected by the combination of sodium valproate (SV) and arsenous trioxide (As2O3), and to explore the relationship between the apoptosis of HL-60 cells induced by the combination of SV and As2O3 and the expression of bcl-2 and bax mRNA. Methods: Various concentrations of SV and 1.0 μmol/L As2O3 were added to exponential growth HL-60 cells . MTT assays were used to measure the growth inhibitory effect of combination of SV and As2O3. Flow cytometry was used to evaluate their apoptosis. RT-PCR was adopted to measure the expression of bcl-2 and bax mRNA. Results: SV was able to induce growth inhibition and apoptosis in HL-60 cells. SV could enhance the growth inhibition and apoptosis induced by 1.0 μmol/L As2O3 alone. The expression of bcl-2 mRNA in HL-60 cells cultured with SV or the combination of SV and As2O3 decreased obviously, but the expression of bax mRNA increased. Conclusion: Combination of SV and As2O3 can synergistically inactivate HL-60 cells, inhibit the cell proliferation and induce apoptosis. The induction of apoptosis induced by SV or the combination of SV and As2O3 may be mediated by down-express bcl-2 mRNA and by up-express bax mRNA.",
        "keywords": [
            "Bax",
            "Apoptosis",
            "HL-60 cells",
            "Arsenous trioxide",
            "Bcl-2",
            "Sodium valproate"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Department of Hematology, the Affiliated Hospital of Nantong University, Nantong "
            },
            {
                "name": "TENG Rong",
                "org": "Department of Hematology, the Affiliated Hospital of Nantong University, Nantong "
            }
        ],
        "venue": "Journal of Nantong University(Medical Sciences)",
        "year": 2008
    },
    "WyzwMhOx": {
        "id": "WyzwMhOx",
        "title": "Experimental study on silencing Guanylyl cyclase-C expression by siRNA facilitates the apoptosis of gastric cancer cells",
        "abstract": "Objective:To investigate the effect of synthetic GC-C short interfering RNA(siRNA)on expression of GC-C gene in human gastric cancer line SGC-7901 cells,and its effect on apoptosis of the cells in vitro.Methods:Based on pSilencerTM4.1-CMV neo vector,GC-C siRNA was constructed.siRNA targeting GC-C mRNA was transfected into SGC-7901 cells.The apoptosis was examined by flow cytometry and TUNEL.Results:48h and 72h after transfected with GC-C siRNA,the flow cytometric analysis verified that the average apoptotic rate of SGC-7901 was 5.48%±0.10% and 5.63%±0.11% respectively,which were higher than that in the control groups(0.50%±0.09%).Furthermore,the apoptotic features of SGC-7901 were noticed by TUNEL assay,of which there were no obvious changes in the control groups.Conclusions:siRNA directed against GC-C can significantly induce apoptosis.It may provide a new target for the biotherapy of gastric cancer.",
        "keywords": [
            "guanylyl cyclase-C",
            "Gastric cancer cell",
            "Cell apoptosis",
            "small interferencing RNA"
        ],
        "authors": [
            {
                "name": "WANG Pengfei",
                "org": "Department of Gastroenterology,the Affiliated Hospital of Nantong University,Nantong "
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Gastroenterology,the Affiliated Hospital of Nantong University,Nantong "
            },
            {
                "name": "MAO Zhenbiao",
                "org": "Department of Gastroenterology,the Affiliated Hospital of Nantong University,Nantong "
            }
        ],
        "venue": "Medical Journal of Communications",
        "year": 2010
    },
    "nysYJ2ng": {
        "id": "nysYJ2ng",
        "title": "The influence of Guanylyl cyclase-C siRNA on growth of gastric cancer cells",
        "abstract": "Objective:To investigate the effect of synthetic GC-C short interfering RNA(siRNA)on growth of human gastric cancer line SGC-7901cells in vitro.Methods:Based on pSilencerTM4.1-CMV neo vector,GC-C siRNA was constructed.siRNA targeting GC-C mRNA was transfected into SGC-7901 cells,and GC-C expression was determined by RT-PCR and indirect immunofluorescence.The ability of cell adhesion was examined by adhesion assay.Results:A pair of siRNA sequences completely matched with target sequences.After transfected with GC-C siRNA,the expression of GC-C mRNA and protein in SGC-7901 cells were reduced by 66.7% and 75.8%,respectively.And the ability of cell adhesion was suppressed in vitro(P<0.05).Conclusions:SiRNA directed against GC-C can significantly suppress adhesion of SGC-7901 cells,which indicated that GC-C may play an important role in the process of gastric cancer's developing and metastasis.",
        "keywords": [
            "Small interferencing RNA",
            "Gastric cancer cell",
            "Guanylyl cyclase-C",
            "Adhesion"
        ],
        "authors": [
            {
                "name": "WANG Pengfei",
                "org": "The Affiliated Hospital of Nantong University,Nantong "
            },
            {
                "name": "ZHANG Jie",
                "org": "The Affiliated Hospital of Nantong University,Nantong "
            },
            {
                "name": "MAO Zhenbiao",
                "org": "The Affiliated Hospital of Nantong University,Nantong "
            }
        ],
        "venue": "Journal of Nantong University(Medical Sciences)",
        "year": 2010
    },
    "41pb8oKX": {
        "id": "41pb8oKX",
        "title": "Effect of trichostatin A and sodium butyrate on variation of Th1/Th2 cell balance after differentiation of peripheral blood CD4~+ T cells",
        "abstract": "Objective To investigate the effects of trichostatin A(TSA) and sodium butyrate(NaB),histone deacetylase inhibitors,on the balance of Th1/Th2 after differentiation of peripheral blood CD4+T cells.Methods Peripheral CD4+T cells were grown in vitro and were divided into TSA group,NaB group,and CON group.The concentrations of IL-4 and IFN-γ(Th1/Th2 factors) in the supernatants were examined by ELISA in each group 48 h later;the expressions of IL-4 and IFN-γ were analyzed by qRT-PCR;and the T-lymphocytes in peripheral blood(PBL) were measured by flow cytometry.Results ELISA showed that the supernatant IFN-γ and IL-4 levels in the TSA and NaB groups were significantly higher than those in the CON group 48 h after treatment with TSA(0.33 μmol/L) and NaB(1.4 mmol/L);real-time quantitative PCR also showed that the expressions of IFN-γ and IL-4 mRNA in TSA and NaB groups were significantly higher than those in the CON group(3.121,2.31;P<0.05).However,flow cytometry showed that the ratios of IFN-γ+ cells/IL-4+ cells were significantly higher in TSA and NaB groups than that in the CON group((1.931,1.551;P<0.05).Conclusion Treatment with TSA and NaB,both histone deacetylase inhibitors,can induce a shift of Th1/ Th2 cell balance toward Th1 cells in peripheral CD4+T cells.",
        "keywords": [
            "sodium butyrate",
            "interleukin-4",
            "interferon-γ",
            "trichostatin A",
            "Th2 cells",
            "Th1 cells"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": " Department of Immunology,College of Medicine,Nantong University,Nantong ,Jiangsu,China"
            },
            {
                "name": "ZHOU Ming-ming",
                "org": " Department of Immunology,College of Medicine,Nantong University,Nantong ,Jiangsu,China"
            },
            {
                "name": "SUN Xiao-lei",
                "org": " Department of Immunology,College of Medicine,Nantong University,Nantong ,Jiangsu,China"
            },
            {
                "name": "WANG Xiao-ying",
                "org": " Department of Immunology,College of Medicine,Nantong University,Nantong ,Jiangsu,China"
            }
        ],
        "venue": "Academic Journal of Second Military Medical University",
        "year": 2011
    },
    "20MNtSvR": {
        "id": "20MNtSvR",
        "title": "Bioequivalence of Famciclovir dispersible tablets in human body",
        "abstract": "OBJECTIVE To study the bioequivalence of Famciclovir dispersible tablets and Famciclovir tablets in human body.METHODS According to a paired,cross-over design,20 healthy male volunteers were randomly divided into two groups.A single oral dose of 0.5 g famciclovir either the test dispersant or its reference was given to them.The plasma concentration of famciclovir was determined by HPLC.The pharmacokinetic parameters were calculated by DAS program and the bioequivalence of the two tablets was evaluated.RESULTS AUC_(0→Tn) of test and reference were 13.80±2.73,13.65±2.42 μg·h·ml~(-1);AUC_(0→∞) were 4.62±2.73,14.35±2.28 μg·h·ml~(-1);C_(max) were 3.42±0.67,3.45±0.67 μg·ml~(-1);T_(max) were 1.11±0.31,1.05±0.25 h,respectively.The bioavailability of the test formation was 101.12%±(8.56%.)CONCLUSION The test famciclovir dispersible tablets were bioequivalent to the reference preparation.",
        "keywords": [
            "HPLC",
            "Dispersible tablets",
            "Bioequivalence",
            "Famciclovir"
        ],
        "authors": [
            {
                "name": "ZHANG Ting-ting",
                "org": "West China School of Pharmacy,Sichuan University,Chengdu ,China"
            },
            {
                "name": "LI Tong-ling",
                "org": "West China School of Pharmacy,Sichuan University,Chengdu ,China"
            },
            {
                "name": "SUN Jian",
                "org": "West China School of Pharmacy,Sichuan University,Chengdu ,China"
            },
            {
                "name": "CHEN Shu-ye",
                "org": "West China School of Pharmacy,Sichuan University,Chengdu ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "West China School of Pharmacy,Sichuan University,Chengdu ,China"
            },
            {
                "name": "HUANG Ting",
                "org": "West China School of Pharmacy,Sichuan University,Chengdu ,China"
            },
            {
                "name": "YANG Lan",
                "org": "West China School of Pharmacy,Sichuan University,Chengdu ,China"
            }
        ],
        "venue": "West China Journal of Pharmaceutical Sciences",
        "year": 2006
    },
    "7I8LTiaV": {
        "id": "7I8LTiaV",
        "title": "Relative bioavailability of Valaciclovir hydrochloride effervescent tablets in healthy volunteers",
        "abstract": "OBJECTIVE To investigate the relative bioavailability of two kinds of Valaciclovir hydrochloride effervescent tablet in healthy volunteers.METHODS According to a paired,cross-over design,18 healthy male volunteers were randomly divided into two groups.A single oral dose of 0.6 g Valaciclovir hydrochloride,either the test effervescent or its reference was given to them.The plasma concentration of Acyclovir was determined by HPLC with ultraviolet detection.The pharmacokinetic parameters were calculated by DAS program and the bioequivalence of the two tablets was evaluated.RESULTS For test and reference preparations,C_(max) were 2.54±0.32 μg·ml~(-1) and 2.59±0.44 μg·ml~(-1),T_(max) were 2.28±0.31 h and 2.22±0.26 h,AUC_(0→Tn) were 10.75±1.804 μg·h·ml~(-1) and 11.35±2.548 μg·h·ml~(-1),AUC_(0→∞) were 11.49±2.06 μg·h·ml~(-1) and 12.09±2.757 μg·h·ml~(-1),t_(1/2) were 2.55±0.69 h and 2.67±0.76 h,respectively.The relative bioavailability of the test was 96.1%.CONCLUSION The test preparation of Valaciclovir hydrochloride effervescent tablets are bioequivalent to the reference preparation.",
        "keywords": [
            "HPLC",
            "Bioequivalence",
            "Acyclovir",
            "Valaciclovir hydrochloride"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "West China School of Pharmacy,Sichuan University,Chengdu ,China"
            },
            {
                "name": "LI Tong-ling",
                "org": "West China School of Pharmacy,Sichuan University,Chengdu ,China"
            },
            {
                "name": "SUN Jian",
                "org": "West China School of Pharmacy,Sichuan University,Chengdu ,China"
            },
            {
                "name": "CHEN Shu-ye",
                "org": "West China School of Pharmacy,Sichuan University,Chengdu ,China"
            },
            {
                "name": "ZHANG Ting-ting",
                "org": "West China School of Pharmacy,Sichuan University,Chengdu ,China"
            },
            {
                "name": "YANG Lan",
                "org": "West China School of Pharmacy,Sichuan University,Chengdu ,China"
            }
        ],
        "venue": "West China Journal of Pharmaceutical Sciences",
        "year": 2006
    },
    "DQzGYuOF": {
        "id": "DQzGYuOF",
        "title": "Separation and identification of chlorogenic acid and related impurities by high performance liquid chromatography-tandem mass spectrometry",
        "abstract": "A method using high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) was established for analysis and identification of chlorogenic acid along with its related impurities. A Gemini C18 HPLC column (4. 6 mm × 150 mm, 5 μm) was used with acetonitrile-water (containing 0. 1% formic acid) (8:92, v/v) as mobile phase. Eight related impurities of chlorogenic acid were identified and their structures were determined by using online HPLC-MS/MS and photodiode array detector (DAD). The method is quick, simple and can be used directly to identify the structure of unknown trace substances in the sample of chlorogenic acid.",
        "keywords": [
            "Chlorogenic acid",
            "High performance liquid chromatography-mass spectrometry/mass spectrometry (HPLC-MS/MS)",
            "Identification",
            "Related impurities"
        ],
        "authors": [
            {
                "name": "Chenxu Tian",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Xiaoping Xü",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Liyun Liao",
                "org": "Chengdu Medical College(Chengdu Medical College,Chengdu Geological College),Chengdu,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Jing Liu",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Sha Zhou",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            }
        ],
        "venue": "Se pu = Chinese journal of chromatography / Zhongguo hua xue hui",
        "year": 2007
    },
    "IgvzJx0j": {
        "id": "IgvzJx0j",
        "title": "Bioequivalence of valaciclovir hydrochloride tablets in human",
        "abstract": "AIM To research the pharmacokinetics,relative bioavailability and bioequivalence of two different valaciclovir hydrochloride tablets in human beings.METHODS A single oral dose of 600 mg of tested valaciclovir hydrochloride tablet and 500 mg of reference valaciclovir hydrochloride tablets were given repectively to 18 healthy male volunteers according to an open randomized crossover design.The acyclovir concentration in plasma was determined by a efficient HPLC-UV method.The data were analysed by DAS program.RESULTS AUC0→Tn of tested tablet and reference one were(11.15±2.05) mg·h·L-1 and(9.82±2.09) mg·h·L-1;AUC0→∞ were(11.80±2.24)mg·h·L-1 and(10.51±2.20)mg·h·L-1;ρmax were(2.85±0.62) mg·L-1 and(2.40±0.51) mg·L-1;tmax were(2.19±0.30) h and(2.19±0.25) h;t12 were(2.51±0.45)h and(2.80±0.35) h,respectively.After dosage adjustment,the main pharmacokinetic parameters of two products showed no statistically significant difference according to DAS results.CONCLUSION Both preparations are bioequivalent.",
        "keywords": [
            "HPLC",
            "valaciclovir hydrochloride",
            "bioavailability"
        ],
        "authors": [
            {
                "name": "CHEN Shu-ye",
                "org": "Department of Clinic Pharmacy,West China School of Pharmacy,Sichuan University,Chengdu ,China"
            },
            {
                "name": "LI Tong-ling",
                "org": "Department of Clinic Pharmacy,West China School of Pharmacy,Sichuan University,Chengdu ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Clinic Pharmacy,West China School of Pharmacy,Sichuan University,Chengdu ,China"
            },
            {
                "name": "ZHANG Ting-ting",
                "org": "Department of Clinic Pharmacy,West China School of Pharmacy,Sichuan University,Chengdu ,China"
            },
            {
                "name": "SUN Jian",
                "org": "Department of Clinic Pharmacy,West China School of Pharmacy,Sichuan University,Chengdu ,China"
            },
            {
                "name": "YANG Lan",
                "org": "Department of Clinic Pharmacy,West China School of Pharmacy,Sichuan University,Chengdu ,China"
            },
            {
                "name": "HUANG Ting",
                "org": "Department of Clinic Pharmacy,West China School of Pharmacy,Sichuan University,Chengdu ,China"
            }
        ],
        "venue": "Chinese Journal of Clinical Pharmacy",
        "year": 2007
    },
    "2ZbHn0Sy": {
        "id": "2ZbHn0Sy",
        "title": "Determination of Paroxetine hydrochloride in tablets by HPLC",
        "abstract": "OBJECTIVE To establish a new RP-HPLC method to determine the content of Paroxetine hydrochloride tablets.METHODS Common ODS collumn was used for separating acided samples with methanol-0.02 mol·L-1 NaH2PO4(60:40,adjusting to pH 4.0 with phosphoric acid) as mobile phase and detective wavelength was set at 295 nm.RESULTS Paroxetine presented a good linearity within the concentration range of 10-100 mg·L-1,meanwhile both the inter-day and intra-day precision was less than 2%,and the mean recovery was 100.15% with RSD of 0.77%.CONCLUSION This method is accurate,simple and low-cost for Paroxetine hydrochloride determination.",
        "keywords": [
            "HPLC",
            "Determination",
            "Paroxetine hydrochloride"
        ],
        "authors": [
            {
                "name": "CHEN Shu-ye",
                "org": "West China School of Pharmacy,Sichuan University,Chengdu ,China"
            },
            {
                "name": "LI Tong-ling",
                "org": "West China School of Pharmacy,Sichuan University,Chengdu ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "West China School of Pharmacy,Sichuan University,Chengdu ,China"
            },
            {
                "name": "ZHANG Ting-ting",
                "org": "West China School of Pharmacy,Sichuan University,Chengdu ,China"
            }
        ],
        "venue": "West China Journal of Pharmaceutical Sciences",
        "year": 2007
    },
    "te4rW7Dx": {
        "id": "te4rW7Dx",
        "title": "Studies on Intestinal Absorption Kinetics of Paroxetine in Rats",
        "abstract": "OBJECTIVE To investigate the absorption kinetics of paroxetine hydrochloride (PRXT) at different segments of gastrointestinal tract under different dosages in rat.METHODS The absorption rate constant Ka of different segments under different dosages was evaluated by in situ recirculation model. The influence of circulation flow rate and P-glycoprotein(P-gp) on Ka was also tested.The concentrations of paronetine were detected by HPLC. RESULTS Ka from different segments was similar(P>0.05),and no distinctive effect on Ka was found (P>0.05). P-gp showed no significant effect (P>0.05) on absorption of PRXT.However, the flow rate showed a remarkable influence on absorption of PRXT (P<0.000 1), and with Pearson's correlation coefficient value as 0.925.The absorption of PRXT in stomach was comparatively poor (<5%).CONCLUSION The absorption of PRXT is a first-order process with a passive diffusion mechanism. PRXT is not the substrate of P-gp, and it is well absorbed in various intestinal tracts. Stomach is not the main area for PRXT absorption. Obviously, Ka is increased with the rising of flow rate.",
        "keywords": [
            "HPLC",
            "paroxetine hydrochloride",
            "seroxat",
            "in situ intestine absoption"
        ],
        "authors": [
            {
                "name": "CHEN Shu-ye",
                "org": "West China School of Pharmacy,Sichuan University,Chengdu ,China"
            },
            {
                "name": "LI Tong-ling",
                "org": "West China School of Pharmacy,Sichuan University,Chengdu ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "West China School of Pharmacy,Sichuan University,Chengdu ,China"
            },
            {
                "name": "ZHANG Ting-ting",
                "org": "West China School of Pharmacy,Sichuan University,Chengdu ,China"
            },
            {
                "name": "JIA Yi-min",
                "org": "West China School of Pharmacy,Sichuan University,Chengdu ,China"
            }
        ],
        "venue": "Chinese Pharmaceutical Journal",
        "year": 2007
    },
    "bBTQHYWJ": {
        "id": "bBTQHYWJ",
        "title": "Comparison of chlorogenic acid content in different kinds of tea",
        "abstract": "OBJECTIVE To find out the contents and distributing charaters of chlorogenic acid in tea from different enviroment and different kinds.To discuss the relationship between chlorogenic acid levels and producing processes.METHODSThe separation was performed on a Gemini C18 column(150 mm×4.6 mm,5 μm) with mobile phase of 0.1% H3PO4-acetonitril–triethylamine(92:8:0.1).The detection wavelength was 323 nm.RESULTSChlorogenic acid could be detected in all kinds of tea(0.01-0.40 mg·g-1).But the contents were different depending on the origin and producing processes.The contents of chlorogenic acid from high to low was:kuding tea>green tea>yellow tea>white tea>flower tea>blue tea>black tea>dark tea.In terms of producing area,tea from north area of the Yangtse river had the highest level,followed by the southern of Yangtse river> southwest of China>southern China.CONCLUSIONThe content of chlorogenic acid is diverse correlated with the place of produce as well as the producing technology of tea.",
        "keywords": [
            "HPLC",
            "Tea",
            "Distribution",
            "Chlorogenic acid"
        ],
        "authors": [
            {
                "name": "ZHOU Sha",
                "org": "West China School of Pharmacy,Sichuan University,Chengdu ,China"
            },
            {
                "name": "WU Xiao-dong",
                "org": "West China School of Pharmacy,Sichuan University,Chengdu ,China"
            },
            {
                "name": "LIU Jing",
                "org": "West China School of Pharmacy,Sichuan University,Chengdu ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "West China School of Pharmacy,Sichuan University,Chengdu ,China"
            },
            {
                "name": "HE Ying-jin",
                "org": "West China School of Pharmacy,Sichuan University,Chengdu ,China"
            },
            {
                "name": "TIAN Xin",
                "org": "West China School of Pharmacy,Sichuan University,Chengdu ,China"
            },
            {
                "name": "HE Wen-wen",
                "org": "West China School of Pharmacy,Sichuan University,Chengdu ,China"
            },
            {
                "name": "XU Xiao-ping",
                "org": "West China School of Pharmacy,Sichuan University,Chengdu ,China"
            }
        ],
        "venue": "West China Journal of Pharmaceutical Sciences",
        "year": 2008
    },
    "01ArDKLl": {
        "id": "01ArDKLl",
        "title": "Study on the pharmacokinetics of combretastatin A4 phosphate in rats",
        "abstract": "OBJECTIVE To study the pharmacokinetics of active compound -combretastatin A4(CA4) which was produced by combretastatin A4 phosphate(CA4P) in rats.METHODS After iv administration of CA4P at the dose of 10,20 mg·kg-1 in rats,the concentrations of CA4 in blood serum at various time points were detected by HPLC method.Concentration-time curves were simulated by DAS program.RESULTS The concentration -time curves of CA4 of two groups were consistent with the two-compartment model.The main pharmacokinetic parameters of two groups were listed as follow:t1/2βwere 34.427±2.849 min and 30.076±3.107 min,Vd were 1.402±0.178 L·kg-1 and 1.568±0.131 L·kg-1,Cl were 0.061±0.003 L·min-1·kg-1 and 0.058±0.003 L·min-1·kg-1,AUC0-t were 132.393±3.144 mg·L-1·min and 291.872±15.555 mg·L-1·min,respectively.CONCLUSION After iv administration of CA4P,CA4 was rapidly metabolized and eliminated as two-compartment model in rats.",
        "keywords": [
            "HPLC",
            "Combretastatin A4",
            "Combretastatin A4 phosphate",
            "Pharmacokinetics"
        ],
        "authors": [
            {
                "name": "HE Ying-jin",
                "org": "West China School of Pharmacy,Sichuan University,Chengdu ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "West China School of Pharmacy,Sichuan University,Chengdu ,China"
            },
            {
                "name": "LIU Jing",
                "org": "West China School of Pharmacy,Sichuan University,Chengdu ,China"
            },
            {
                "name": "HE Wen-wen",
                "org": "West China School of Pharmacy,Sichuan University,Chengdu ,China"
            },
            {
                "name": "ZHOU Sha",
                "org": "West China School of Pharmacy,Sichuan University,Chengdu ,China"
            },
            {
                "name": "TIAN Xin",
                "org": "West China School of Pharmacy,Sichuan University,Chengdu ,China"
            },
            {
                "name": "XU Xiao-ping",
                "org": "West China School of Pharmacy,Sichuan University,Chengdu ,China"
            }
        ],
        "venue": "West China Journal of Pharmaceutical Sciences",
        "year": 2008
    },
    "aL2EPJk3": {
        "id": "aL2EPJk3",
        "title": "HTOutlier: Hardware Trojan detection with side-channel signature outlier identification.",
        "abstract": "Hardware Trojan (HT) is a growing concern for the semiconductor industry. As a non-invasive and inexpensive approach, side-channel analysis methods based on signatures such as power, current, or circuit delay are widely used for HT detection. However, the effectiveness of these methods is greatly challenged by the ever-increasing process variation (PV) effects with technology scaling. In this work, considering the inherent relationship among side-channel signatures in a chip, we formulate the HT detection problem as a signature outlier identification problem, and solve it by comparing each signature with an estimated value from other signatures. Experimental results on benchmark circuits show that the proposed technique is much more effective than existing solutions. © 2012 IEEE.",
        "keywords": [
            "logic gates",
            "chip",
            "estimation",
            "hardware",
            "digital signatures",
            "silicon",
            "correlation",
            "integrated circuit design",
            "process variation"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Haile Yu",
                "org": ""
            },
            {
                "name": "Qiang Xu",
                "org": ""
            }
        ],
        "venue": "HOST",
        "year": 2012
    },
    "BI9fiw2q": {
        "id": "BI9fiw2q",
        "title": "On hardware Trojan design and implementation at register-transfer level",
        "abstract": "There have been a number of hardware Trojan (HT) designs at register-transfer level (RTL) in the literature, which mainly describe their malicious behaviors and trigger mechanisms. Generally speaking, the stealthiness of the HTs is shown with extremely low sensitization probability of the trigger events. In practice, however, based on the fact that HTs are not sensitized with verification test cases (otherwise their malicious behaviors would have manifested themselves), designers could focus on verification corners for HT detection. Consequently, a stealthy HT not only requires to be hard to trigger, but also needs to be able to evade those hardware trust verification techniques based on “unused circuit identification (UCI)”. In this paper, we present new HT design and implementation techniques that are able to achieve the above objectives. In addition, attackers would like to be able to control their HTs easily, which is also considered in the proposed HT design methodology. Experimental results demonstrate that HTs constructed with the proposed technique are both hard to be detected and easy to be controlled when compared to existing HTs shown in the literature.",
        "keywords": [
            "trigger mechanisms",
            "rtl",
            "malicious behaviors",
            "trusted computing",
            "hardware trojan design",
            "trust verification techniques",
            "trigger events",
            "sensitization probability",
            "unused circuit identification",
            "register transfer level",
            "security of data",
            "verification test cases",
            "security",
            "measurement",
            "radiation detectors",
            "hardware",
            "design methodology"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Qiang Xu",
                "org": ""
            }
        ],
        "venue": "HOST",
        "year": 2013
    },
    "WsXicg09": {
        "id": "WsXicg09",
        "title": "VeriTrust: verification for hardware trust",
        "abstract": "Hardware Trojans (HTs) implemented by adversaries serve as backdoors to subvert or augment the normal operation of infected devices, which may lead to functionality changes, sensitive information leakages, or Denial of Service attacks. To tackle such threats, this paper proposes a novel verification technique for hardware trust, namely VeriTrust, which facilitates to detect HTs inserted at design stage. Based on the observation that HTs are usually activated by dedicated trigger inputs that are not sensitized with verification test cases, VeriTrust automatically identifies such potential HT trigger inputs by examining verification corners. The key difference between VeriTrust and existing HT detection techniques is that VeriTrust is insensitive to the implementation style of HTs. Experimental results show that VeriTrust is able to detect all HTs evaluated in this paper (constructed based on various HT design methodologies shown in the literature) at the cost of moderate extra verification time, which is not possible with existing solutions.",
        "keywords": [
            "novel verification technique",
            "design stage",
            "potential ht trigger input",
            "hardware trust",
            "dedicated trigger input",
            "verification test case",
            "verification corner",
            "hardware trojan",
            "moderate extra verification time",
            "various ht design methodology",
            "ht detection technique",
            "sram",
            "puf",
            "trusted computing",
            "computer network security",
            "signature",
            "hardware security"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "The Chinese University of Hong Kong, Shatin, N.T., Hong Kong"
            },
            {
                "name": "Feng Yuan",
                "org": "The Chinese University of Hong Kong, Shatin, N.T., Hong Kong"
            },
            {
                "name": "Lingxiao Wei",
                "org": "The Chinese University of Hong Kong, Shatin, N.T., Hong Kong"
            },
            {
                "name": "Zelong Sun",
                "org": "The Chinese University of Hong Kong, Shatin, N.T., Hong Kong"
            },
            {
                "name": "Qiang Xu",
                "org": "The Chinese University of Hong Kong, Shatin, N.T., Hong Kong"
            }
        ],
        "venue": "DAC",
        "year": 2013
    },
    "IHO06wkQ": {
        "id": "IHO06wkQ",
        "title": "ForTER: a forward error correction scheme for timing error resilience",
        "abstract": "With technology scaling, integrated circuits suffer from increasingly severe static and dynamic variations, which often manifest themselves as infrequent timing errors on circuit speed paths, if a large timing guard-band is not reserved. This paper presents a new forward timing error correction scheme, namely ForTER, which predicts whether the occurrence of timing errors would propagate to the next level of sequential elements and corrects them without necessarily borrowing timing slack. The proposed technique can be combined with other timing error resilient circuit design techniques to further improve circuit performance, as demonstrated in our experimental results with various benchmark circuits.\n\n",
        "keywords": [
            "forward error correction scheme",
            "timing error resilience",
            "timing slack",
            "circuit performance",
            "various benchmark circuit",
            "large timing guard-band",
            "infrequent timing error",
            "timing error resilient circuit",
            "timing error",
            "integrated circuit",
            "new forward timing error",
            "circuit speed path",
            "forward error correction"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "The Chinese University of Hong Kong, Shatin, N.T., Hong Kong"
            },
            {
                "name": "Feng Yuan",
                "org": "The Chinese University of Hong Kong, Shatin, N.T., Hong Kong"
            },
            {
                "name": "Rong Ye",
                "org": "The Chinese University of Hong Kong, Shatin, N.T., Hong Kong"
            },
            {
                "name": "Qiang Xu",
                "org": "The Chinese University of Hong Kong, Shatin, N.T., Hong Kong"
            }
        ],
        "venue": "ICCAD",
        "year": 2013
    },
    "LS4S18GR": {
        "id": "LS4S18GR",
        "title": "DeTrust: Defeating Hardware Trust Verification with Stealthy Implicitly-Triggered Hardware Trojans",
        "abstract": "Hardware Trojans (HTs) inserted at design time by malicious insiders on the design team or third-party intellectual property (IP) providers pose a serious threat to the security of computing systems. Researchers have proposed several hardware trust verification techniques to mitigate such threats, and some of them are shown to be able to effectively flag all suspicious HTs implemented in the Trust-Hub hardware backdoor benchmark suite. No doubt to say, adversaries would adjust their tactics of attacks accordingly and it is hence essential to examine whether new types of HTs can be designed to defeat these hardware trust verification techniques. In this paper, we present a systematic HT design methodology to achieve the above objective, namely \\\\emph{DeTrust}. Given an HT design, DeTrust keeps its original malicious behavior while making the HT resistant to state-of-the-art hardware trust verification techniques by manipulating its trigger designs. To be specific, DeTrust implements stealthy implicit triggers for HTs by carefully spreading the trigger logic into multiple sequential levels and combinational logic blocks and combining the trigger logic with the normal logic, so that they are not easily differentiable from normal logic. As shown in our experimental results, adversaries can easily employ DeTrust to evade hardware trust verification. We close with a discussion on how to extend existing solutions to alleviate the threat posed by DeTrust. However, they generally suffer from high computational complexity, calling for more advanced techniques to ensure hardware trust.",
        "keywords": [
            "hardware security",
            "miscellaneous",
            "hardware trojan",
            "backdoors",
            "implicit trigger"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Feng Yuan",
                "org": ""
            },
            {
                "name": "Qiang Xu",
                "org": ""
            }
        ],
        "venue": "ACM Conference on Computer and Communications Security",
        "year": 2014
    },
    "byxSa4E0": {
        "id": "byxSa4E0",
        "title": "On trojan side channel design and identification",
        "abstract": "Trojan side channels (TSCs) are serious threats to the security of cryptographic systems because they facilitate to leak secret keys to attackers via covert side channels that are unknown to designers. To tackle this problem, we present a new hardware Trojan detection technique for TSCs. To be specific, we first investigate general power-based TSC designs and discuss the tradeoff between their hardware cost and the complexity of the key cracking process. Next, we present our TSC identification technique based on the correlation between the key and the covert physical side channels used by attackers. Experimental results demonstrate the effectiveness of the proposed solution.\n\n",
        "keywords": [
            "tsc identification technique",
            "invasive software",
            "trojan side channel identification",
            "cryptography",
            "general power-based tsc design",
            "trojan side channel design",
            "covert side channels",
            "cryptographic systems",
            "key cracking process complexity",
            "hardware",
            "smart home",
            "correlation",
            "cyberattack",
            "cybersecurity"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "The Chinese University of Hong Kong"
            },
            {
                "name": "Guantong Su",
                "org": "Tsinghua University"
            },
            {
                "name": "Yannan Liu",
                "org": "The Chinese University of Hong Kong"
            },
            {
                "name": "Lingxiao Wei",
                "org": "The Chinese University of Hong Kong"
            },
            {
                "name": "Feng Yuan",
                "org": "The Chinese University of Hong Kong"
            },
            {
                "name": "Guoqiang Bai",
                "org": "Tsinghua University"
            },
            {
                "name": "Qiang Xu",
                "org": "The Chinese University of Hong Kong"
            }
        ],
        "venue": "ICCAD",
        "year": 2014
    },
    "yQ5WWGOx": {
        "id": "yQ5WWGOx",
        "title": "Vulnerability analysis for crypto devices against probing attack",
        "abstract": "Probing attack is a severe threat for the security of hardware cryptographic modules (HCMs). In this paper, we make the first step to evaluate the vulnerability of HCMs against probing attack, wherein we investigate the probing complexity and the key candidate reduction capability for probing attack on every signal in the circuit. We also present approximate solutions for the calculation of the proposed metrics to reduce computational complexity. Experimental results demonstrate that the proposed evaluation metric is both effective and efficient.",
        "keywords": [
            "cryptodevices",
            "hcm security",
            "probing attack",
            "key candidate reduction capability",
            "security",
            "cryptography",
            "hcm vulnerability analysis",
            "computational complexity",
            "probing complexity",
            "hardware cryptographic modules"
        ],
        "authors": [
            {
                "name": "Lingxiao Wei",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Feng Yuan",
                "org": ""
            },
            {
                "name": "Yannan Liu",
                "org": ""
            },
            {
                "name": "Junfeng Fan",
                "org": ""
            },
            {
                "name": "Qiang Xu",
                "org": ""
            }
        ],
        "venue": "ASP-DAC",
        "year": 2015
    },
    "4iU71BDW": {
        "id": "4iU71BDW",
        "title": "On the premises and prospects of timing speculation",
        "abstract": "Timing speculation (TS), being able to detect and correct circuit timing errors at runtime, is a promising alternative solution to mitigate the ever-increasing variation effects in nanometer circuits. The potential energy-efficiency improvement, however, is limited by the circuit 'timing wall\\\", a critical operating point caused by conventional circuit optimization techniques (e.g., gate sizing). With a given circuit netlist, we study the bound of the potential benefits provided by TS techniques in this work, which facilitate designers to decide whether it worths the effort to implement a timing-speculative circuit. Experimental results on benchmark circuits demonstrate the effectiveness of the proposed methodology.",
        "keywords": [
            "logic gates",
            "block cipher",
            "low power electronics",
            "optimization",
            "nanoelectronics",
            "integrated circuit design",
            "benchmark testing",
            "error probability",
            "threshold voltage"
        ],
        "authors": [
            {
                "name": "Rong Ye",
                "org": "The Chinese University of Hong Kong, Shatin, N.T., Hong Kong"
            },
            {
                "name": "Feng Yuan",
                "org": "The Chinese University of Hong Kong, Shatin, N.T., Hong Kong"
            },
            {
                "name": "Jie Zhang",
                "org": "The Chinese University of Hong Kong, Shatin, N.T., Hong Kong"
            },
            {
                "name": "Qiang Xu",
                "org": "The Chinese University of Hong Kong, Shatin, N.T., Hong Kong"
            }
        ],
        "venue": "DATE",
        "year": 2015
    },
    "DNTB0aDh": {
        "id": "DNTB0aDh",
        "title": "Efficacy obeservation of different incremental regimens of narrow-band ultraviolet B phototherapy in psoriasis vulgaris",
        "abstract": "Objective: To study the efficacy of different incremental regimens of 311nm narrow-band ultraviolet B (NB-UVB) phototherapy in psoriasis vulgaris and determine whether maintenance NB-UVB affects the duration of remission. Methods: Twenty five patients with symmetrical psoriasis were treated by 311nm NB-UVB radiation using randomized half body, single blind method and twice weekly exposures to the phototherapy. After clinically significant improvement, 60 patients were randomly assigned to one of two groups, namely maintenance or no maintenance phototherapy. Both groups were followed up for 1 year. Results: PASI score more than 75 was achieved in 23 of 25(92%) treated patients. Of these 23 patients, the high increment dose regimen got better efficacy in shorter time. However, the low increment dose regimen achieved a 10% reduction in the median cumulative dose to clearance(19.64±3.87 vs. 21.90±3.17 J/cm2,P < 0.05) with more exposures(17.04±2.20 vs.14.96±1.56 times, P < 0.05) and extra costs(187.44±24.28 vs. 164.56±17.24 yuan, P < 0.05). For 60 patients in the reviewed group, Life quality table analysis indicated no statistically significant difference for the probability of remaining in remission between maintenance and no maintenance groups. Conclusions: Radiation of NB-UVB was safe and effective for psoriasis vulgaris; The long-term risk of low increment dose regimen is probably less than that of high increment dose regimen. However, the high increment dose regimen is characteristic with better efficacy in shorter time, fewer exposures and costs. The maintenance NB-UVB may not a recommendation for those patients with longer remission durations.",
        "keywords": [
            "MED",
            "NB-UVB",
            "Psoriasis vulgaris"
        ],
        "authors": [
            {
                "name": "YU Bo",
                "org": "Department of Dermatology, Shenzhen Hospital, Peking University, Shenzhen , China"
            },
            {
                "name": "ZHONG Qi-li",
                "org": "Department of Dermatology, Shenzhen Hospital, Peking University, Shenzhen , China"
            },
            {
                "name": "Jie Zhang",
                "org": "Peking University(Peking University),Beijing,China"
            },
            {
                "name": "Yong Shao",
                "org": "Peking University(Peking University),Beijing,China"
            },
            {
                "name": "ZHU Yi-nan",
                "org": "Department of Dermatology, Shenzhen Hospital, Peking University, Shenzhen , China"
            }
        ],
        "venue": "Journal of Clinical Dermatology",
        "year": 2007
    },
    "t5i66sqP": {
        "id": "t5i66sqP",
        "title": "Copy number variations of the human histamine H4 receptor gene are associated with systemic lupus erythematosus.",
        "abstract": "Systemic lupus erythematosus (SLE) is a complex genetic disease; the histamine H4 receptor (HRH4) has been shown to be related to different kinds of autoimmune disorders; and copy number variations (CNVs) have been found to be associated with various types of diseases.To explore a possible association between HRH4 (formerly H4R) CNVs and the risk of SLE.Genomic DNA and RNA from 340 patients with SLE and 392 healthy controls were extracted, and CNVs and mRNA levels of HRH4 were examined.The expression of HRH4 mRNA was significantly increased in patients with SLE compared with controls. Amplification of HRH4 copy numbers significantly increased the risk of SLE [P < 0·001, odds ratio (OR) 2·26, 95% confidence interval (CI) 1·50-3·40]. HRH4 amplifications also positively correlated with the incidence of arthritis (P = 0·019, OR 1·96, 95% CI 1·11-3·47), and proteinuria (P < 0·001, OR 2·95, 95% CI 1·73-5·00) and antinuclear antibody abnormalities (P < 0·001, OR 2·97, 95% CI 1·66-5·33). Deletions of HRH4 copy numbers were protective against proteinuria (P = 0·03, OR 0·50, 95% CI 0·26-0·94).CNVs of the HRH4 gene are associated with SLE.",
        "keywords": [
            "copy number variations",
            "histamine h4 receptor",
            "systemic lupus erythematosus",
            "copy number variation"
        ],
        "authors": [
            {
                "name": "B Yu",
                "org": "Peking University(Peking University),Beijing,China"
            },
            {
                "name": "Y Shao",
                "org": "Peking University(Peking University),Beijing,China"
            },
            {
                "name": "P Li",
                "org": "Shenzhen Children's Hospital(Shenzhen Children's Hospital,Shenzhen Children Hospital),Qingshuihe, Shenzhen,China"
            },
            {
                "name": "J Zhang",
                "org": "Peking University(Peking University),Beijing,China"
            },
            {
                "name": "Q Zhong",
                "org": "Peking University(Peking University),Beijing,China"
            },
            {
                "name": "H Yang",
                "org": "Peking University(Peking University),Beijing,China"
            },
            {
                "name": "X Hu",
                "org": "Peking University(Peking University),Beijing,China"
            },
            {
                "name": "B Chen",
                "org": "Peking University(Peking University),Beijing,China"
            },
            {
                "name": "X Peng",
                "org": "Peking University(Peking University),Beijing,China"
            },
            {
                "name": "Q Wu",
                "org": "Shenzhen-PKU-HKUST Medical Center(Shenzhen-PKU-HKUST Medical Center,Shenzhen PKU-HKUST Medical Center),Qingshuihe, Shenzhen,China"
            },
            {
                "name": "Y Chen",
                "org": "Jinan University(Jinan University),Jinan,China"
            },
            {
                "name": "M Guan",
                "org": "Huashan Hospital(Huashan Hospital,Hua Shan Hospital,Fudan University),Shanghai,China"
            },
            {
                "name": "J Wan",
                "org": "Hong Kong University of Science and Technology(Hong Kong University of Science and Technology,Hong Kong Univ. of Sci. and Technol.),Hong Kong,China"
            },
            {
                "name": "W Zhang",
                "org": "Jinan University(Jinan University),Jinan,China"
            }
        ],
        "venue": "The British journal of dermatology",
        "year": 2010
    },
    "VToSxLiG": {
        "id": "VToSxLiG",
        "title": "High-resolution melting analysis of ADAMTS18 methylation levels in gastric, colorectal and pancreatic cancers.",
        "abstract": "A disintegrin and metalloprotease with trombospondin motifs (ADAMTS) is a family of proteins characterized by the presence of a metalloproteinase domain linked to a variety of specialized ancillary domains. ADAMTS18 is a putative tumor suppressive gene related to nasopharyngeal carcinoma. We used high-resolution melting (HRM) analysis to detect the methylation levels of ADAMTS18 gene in 100 gastric cancers, 100 colorectal cancers, 70 pancreatic cancers, and equal number of adjacent normal tissues. The frequency of ADAMTS18 methylation in all three types of cancers was significantly higher than that in normal tissues. Expression levels of ADAMTS18 were inversely correlated with methylation levels. No significant association was found between ADAMTS18 methylation status and TNM staging in the cancers. In summary, epigenetic regulation of ADAMTS18 was associated with carcinogenesis. The application of HRM analysis is a fast and high-throughput way to investigate the epigenetic status of ADAMTS18.",
        "keywords": [
            "adamts18",
            "methylation",
            "pancreatic cancer",
            "hrm",
            "gastric cancer",
            "colorectal cancer",
            "high throughput",
            "high resolution melting"
        ],
        "authors": [
            {
                "name": "Zhi Li",
                "org": "Zhengzhou University(Zhengzhou University),Zhengzhou,China"
            },
            {
                "name": "Wei Zhang",
                "org": "Jinan University, School of Medicine(Medical College of Jinan University,Jinan University,Ji'nan University),Guangzhou,China"
            },
            {
                "name": "Yong Shao",
                "org": "Shenzhen-PKU-HKUST Medical Center(Shenzhen-PKU-HKUST Medical Center,Shenzhen PKU-HKUST Medical Center),Qingshuihe, Shenzhen,China"
            },
            {
                "name": "Chao Zhang",
                "org": "Shenzhen-PKU-HKUST Medical Center(Shenzhen-PKU-HKUST Medical Center,Shenzhen PKU-HKUST Medical Center),Qingshuihe, Shenzhen,China"
            },
            {
                "name": "Qi Wu",
                "org": "Shenzhen-PKU-HKUST Medical Center(Shenzhen-PKU-HKUST Medical Center,Shenzhen PKU-HKUST Medical Center),Qingshuihe, Shenzhen,China"
            },
            {
                "name": "Hong Yang",
                "org": "Peking University Shenzhen Hospital(Peking University Shenzhen Hospital,Shenzhen Hospital Peking University),,China"
            },
            {
                "name": "Xiangbin Wan",
                "org": "Henan Province Tumor Hospital(Henan Province Tumor Hospital,Henan Province Hospital),Zhengzhou,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Peking University Shenzhen Hospital(Peking University Shenzhen Hospital,Shenzhen Hospital Peking University),,China"
            },
            {
                "name": "Ming Guan",
                "org": "Huashan Hospital(Huashan Hospital,Hua Shan Hospital,Fudan University),Shanghai,China"
            },
            {
                "name": "Jun Wan",
                "org": "Shenzhen-PKU-HKUST Medical Center(Shenzhen-PKU-HKUST Medical Center,Shenzhen PKU-HKUST Medical Center),Qingshuihe, Shenzhen,China"
            },
            {
                "name": "Bo Yu",
                "org": "Shenzhen-PKU-HKUST Medical Center(Shenzhen-PKU-HKUST Medical Center,Shenzhen PKU-HKUST Medical Center),Qingshuihe, Shenzhen,China"
            }
        ],
        "venue": "Medical oncology (Northwood, London, England)",
        "year": 2010
    },
    "IPdJjrkh": {
        "id": "IPdJjrkh",
        "title": "Copy number variations of interleukin-17F, interleukin-21, and interleukin-22 are associated with systemic lupus erythematosus.",
        "abstract": "Systemic lupus erythematosus (SLE) represents the classic prototype of systemic autoimmune disease. The identification of the Th17 cell subset has provided new understanding regarding the underlying mechanisms of autoimmunity. Copy number variations (CNVS) have been discovered to have phenotypic consequences and are associated with various types of diseases. We undertook this study to explore a possible association between CNVS of Th17 cell-related genes and the risk of SLE.We extracted genomic DNA and RNA from 938 SLE patients and 1,017 healthy controls. We examined CNVS of Th17 cell-related genes, including retinoic acid receptor-related orphan nuclear receptor γt, STAT-3, interleukin-6 (IL-6), transforming growth factor β, tumor necrosis factor α, IL-17A, IL-17F, IL-21, IL-22, IL-23A, CCL20, and CCR6, and levels of messenger RNA (mRNA) for IL-17F, IL-21, and IL-22.Genotype and allele frequencies for copy number amplifications of IL-17F, IL-21, and IL-22 were found to be significantly higher in SLE patients than in healthy controls. CNVS of IL-17F, IL-21, and IL-22 had no synergistic contribution to SLE. The mRNA expression of IL-17F, IL-21, and IL-22 in the samples with >2 copies of DNA was significantly higher than that in those with 2 copies of DNA.Our findings indicate that CNVS of IL-17F, IL-21, and IL-22 are associated with the risk of SLE.",
        "keywords": [],
        "authors": [
            {
                "name": "Bo Yu",
                "org": "Peking University(Peking University),Beijing,China"
            },
            {
                "name": "Ming Guan",
                "org": "Huashan Hospital(Huashan Hospital,Hua Shan Hospital,Fudan University),Shanghai,China"
            },
            {
                "name": "Yinghui Peng",
                "org": "Jinan University(Jinan University),Jinan,China"
            },
            {
                "name": "Yong Shao",
                "org": "Peking University(Peking University),Beijing,China"
            },
            {
                "name": "Chao Zhang",
                "org": "Peking University(Peking University),Beijing,China"
            },
            {
                "name": "Xupeng Yue",
                "org": "Peking University(Peking University),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Peking University(Peking University),Beijing,China"
            },
            {
                "name": "Hong Yang",
                "org": "Peking University(Peking University),Beijing,China"
            },
            {
                "name": "Hejian Zou",
                "org": "Huashan Hospital(Huashan Hospital,Hua Shan Hospital,Fudan University),Shanghai,China"
            },
            {
                "name": "Wencai Ye",
                "org": "Jinan University(Jinan University),Jinan,China"
            },
            {
                "name": "Jun Wan",
                "org": "Peking University(Peking University),Beijing,China"
            },
            {
                "name": "Wei Zhang",
                "org": "Peking University(Peking University),Beijing,China"
            }
        ],
        "venue": "Arthritis and rheumatism",
        "year": 2011
    },
    "8rR4vtU3": {
        "id": "8rR4vtU3",
        "title": "A combined A431 cell membrane chromatography and online high performance liquid chromatography/mass spectrometry method for screening compounds from total alkaloid of Radix Caulophylli acting on the human EGFR.",
        "abstract": "We have developed an online analytical method that combines A431 cell membrane chromatography (A431/CMC) with high performance liquid chromatography and mass spectrometry (LC/MS) for identifying active components from Radix Caulophylli acting on human EGFR. Retention fractions on A431/CMC model were captured onto an enrichment column and the components were directly analyzed by combining a 10-port column switcher with an LC/MS system for separation and preliminary identification. Using Sorafenib tosylate as a positive control, taspine and caulophine from Radix Caulophylli were identified as the active molecules which could act on the EGFR. This A431/CMC-online-LC/MS method can be applied for screening active components acting on EGFR from traditional Chinese medicines exemplified by Radix Caulophylli and will be of great utility in drug discovery using natural medicinal herbs as a source of novel compounds.",
        "keywords": [
            "egfr",
            "radix caulophylli",
            "high performance liquid chromatography/mass spectrometry (lc/ms)",
            "cell membrane chromatography (cmc)",
            "traditional chinese medicine",
            "high performance liquid chromatography",
            "mass spectrometry",
            "drug discovery"
        ],
        "authors": [
            {
                "name": "Meng Sun",
                "org": "School of Medicine, Xi’an Jiaotong University, Xi’an 710061, China"
            },
            {
                "name": "Jing Ren",
                "org": "School of Medicine, Xi’an Jiaotong University, Xi’an 710061, China"
            },
            {
                "name": "Hui Du",
                "org": "School of Medicine, Xi’an Jiaotong University, Xi’an 710061, China"
            },
            {
                "name": "Yanmin Zhang",
                "org": "School of Medicine, Xi’an Jiaotong University, Xi’an 710061, China"
            },
            {
                "name": "Jie Zhang",
                "org": "School of Medicine, Xi’an Jiaotong University, Xi’an 710061, China"
            },
            {
                "name": "Sicen Wang",
                "org": ""
            },
            {
                "name": "Langchong He",
                "org": "School of Medicine, Xi’an Jiaotong University, Xi’an 710061, China"
            }
        ],
        "venue": "Journal of chromatography. B, Analytical technologies in the biomedical and life sciences",
        "year": 2010
    },
    "NucPsZcb": {
        "id": "NucPsZcb",
        "title": "EGFR/cell membrane chromatography-online-high performance liquid chromatography/mass spectrometry method for screening EGFR antagonists from <Emphasis Type=\"Italic\">Radix Angelicae Pubescentis</Emphasis>",
        "abstract": "The intracellular kinase domains of epidermal growth factor receptor(EGFR) in some tumor cells such as human epidermal squamous cells(A431 cells) are an important target for drug discovery.We have developed a new EGFR cell membrane chromatography(EGFR/CMC)-online-high performance liquid chromatography/mass spectrometry(HPLC/MS) method for screening anti-EGFR antagonists form medicinal herbs such as Radix Angelicae Pubescentis.In this study,the HEK293 EGFR cells with high expression of EGFR were used to prepare cell membrane stationary phase(CMSP) in EGFR/CMC model.The retention fractions on EGFR/CMC model were directly analyzed by combining a 10 port columns switcher with a HPLC/MS system online.As the results,osthole from Radix angelicae pubescentis were found to be the active components acted on EGFR like dasatinib as a control drug.There were a good relationship with their inhibiting effects on EGFR secretion and HEK293 EGFR cell growth in vitro.This new A431/CMC-online-HPLC/MS method can be applied for screening anti-EGFR antagonists from TCMs for instance Radix angelicae pubescentis.It will be a useful method for drug discovery with natural medicinal herbs as a leading compound resource.",
        "keywords": [
            "EGFR cell membrane chromatography",
            " high performance liquid chromatography/mass spectrometry",
            " anti-EGFR antagonists",
            " Radix Angelicae Pubescentis"
        ],
        "authors": [
            {
                "name": "SiCen Wang",
                "org": "Key Laboratory of Environment and Genes Related to Diseases, Ministry of Education; School of Medicine,Xi’an Jiaotong University,Xi’an,China"
            },
            {
                "name": "Meng Sun",
                "org": "Key Laboratory of Environment and Genes Related to Diseases, Ministry of Education; School of Medicine,Xi’an Jiaotong University,Xi’an,China"
            },
            {
                "name": "YanMin Zhang",
                "org": "Key Laboratory of Environment and Genes Related to Diseases, Ministry of Education; School of Medicine,Xi’an Jiaotong University,Xi’an,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Key Laboratory of Environment and Genes Related to Diseases, Ministry of Education; School of Medicine,Xi’an Jiaotong University,Xi’an,China"
            },
            {
                "name": "LangChong He",
                "org": "Key Laboratory of Environment and Genes Related to Diseases, Ministry of Education; School of Medicine,Xi’an Jiaotong University,Xi’an,China"
            }
        ],
        "venue": "中国科学:化学(英文版)",
        "year": 2010
    },
    "5bZ4Eywb": {
        "id": "5bZ4Eywb",
        "title": "Antitumor activity of taspine by modulating the EGFR signaling pathway of Erk1/2 and Akt in vitro and in vivo.",
        "abstract": "EGFR, as a critical signaling pathway in many human tumors, has become an important target of cancer drug design. Taspine has shown meaningful angiogenesis activity in previous studies. This paper is to investigate the antitumor action of taspine by modulating the EGFR signaling pathway. The study determined the expression of key signaling molecules of EGFR (EGFR, Akt, p-Akt, Erk, and p-Erk) by Western blot and real-time PCR and analyzed their correlations with subsequent reactions. In addition, the cell proliferation, migration, and EGF production were examined by MTT, transwell system, and ELISA. The antitumor activity in vivo was carried out by xenograft in athymic mice. The results showed that taspine could inhibit A431 and Hek293/EGFR cell proliferation and A431 cell migration as well as EGF production. Compared to the negative control, EGFR, Akt, and phosphorylation of Akt were significantly inhibited by taspine treatment in A431 and HEK293/EGFR cells. Consistent with the inhibition of Akt activity, Erk1/2 and its phosphorylation were reduced. Moreover, taspine inhibited A431 xenograft tumor growth. These results suggest that EGFR activated by EGF and its downstream signaling pathways proteins could be downregulated by taspine in a dose-dependent manner. The antitumor mechanism of taspine through the EGFR pathway lies in the ability to inhibit A431 cell proliferation and migration by reducing EGF secretion. This occurs through the repression of EGFR which mediates not only MAPK (Erk1/2) but also Akt signals.",
        "keywords": [
            "egfr",
            "egfr inhibitor",
            "signaling pathway",
            "taspine"
        ],
        "authors": [
            {
                "name": "Yanmin Zhang",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Lei Zheng",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Bingling Dai",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Nan Wang",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Yinnan Chen",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Langchong He",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            }
        ],
        "venue": "Planta medica",
        "year": 2011
    },
    "DOH6Z5kH": {
        "id": "DOH6Z5kH",
        "title": "A high expression EGFR/cell membrane chromatography and online high performance liquid chromatography/mass spectrometry method for screening EGFR antagonists from Rhizoma Polygoni Cuspidati",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "meng sun",
                "org": ""
            },
            {
                "name": "yanmin zhang",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "sicen wang",
                "org": ""
            },
            {
                "name": "langchong he",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2011
    },
    "vqfYfwE4": {
        "id": "vqfYfwE4",
        "title": "Anti-proliferative and apoptotic effects of the novel taspine derivative tas41 in the Caco-2 cell line.",
        "abstract": "Taspine was screened and isolated for the first time from Radix et Rhizoma Leonticis. Tas41 is a novel taspine derivative. We investigated the effects of tas41 on proliferation of the Caco-2 cell line using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT), a fluorescence-activated cell sorter (FACS), enzyme-linked immunosorbent assay (ELISA), reverse transcription-polymerase chain reaction (RT-PCR) and western blotting (WB). Changes in the cell cycle, apoptosis, activation of caspase-3, caspase-8 and caspase-9, and expressions of vascular endothelial growth factor (VEGF) and epidermal growth factor (EGF) were investigated after Caco-2 cells were treated with tas41. At the same time, expressions of apoptosis protein bcl-2 and bax were determined. Tas41 was found to induce apoptosis in a concentration-dependent manner as confirmed by DNA fragmentation analysis, TUNEL assay and flow cytometry. Protein and mRNA expressions of EGF, VEGF, CDK2, bcl-2 and bax were evaluated by ELISA, WB and RT-PCR. Tas41 had a better anti-proliferative effect than taspine on Caco-2 cells. A DNA ladder and apoptosis was observed, and the increased apoptotic activity by tas41 was accompanied by a decrease in the expression of VEGF protein and mRNA. The activities of caspase-3, caspase-8 and caspase-9 were significantly increased in cells treated with tas41 compared with those in the control group. In addition, protein and mRNA expressions of bcl-2 were decreased, and protein and mRNA expressions of bax were increased. These findings demonstrate that tas41 can inhibit the proliferation of, and induce apoptosis in, Caco-2 cells by activating caspase-3, caspase-8 and caspase-9, downregulating the expressions of VEGF, upregulating the ratio of bax/bcl-2.",
        "keywords": [
            "apoptosis",
            "tas41",
            "caco-2 cells",
            "protein expression",
            "proliferation",
            "dna fragmentation",
            "flow cytometry",
            "vascular endothelial growth factor",
            "caco 2 cells",
            "reverse transcription polymerase chain reaction",
            "control group",
            "cell cycle"
        ],
        "authors": [
            {
                "name": "Yanmin Zhang",
                "org": "School of Medicine, Xi’an Jiaotong University, No. 76, Yanta Weststreet, #120, Xi’an, Shaanxi Province 710061, PR China"
            },
            {
                "name": "Jie Zhang",
                "org": "School of Medicine, Xi’an Jiaotong University, No. 76, Yanta Weststreet, #120, Xi’an, Shaanxi Province 710061, PR China"
            },
            {
                "name": "Bingling Dai",
                "org": "School of Medicine, Xi’an Jiaotong University, No. 76, Yanta Weststreet, #120, Xi’an, Shaanxi Province 710061, PR China"
            },
            {
                "name": "Nan Wang",
                "org": "School of Medicine, Xi’an Jiaotong University, No. 76, Yanta Weststreet, #120, Xi’an, Shaanxi Province 710061, PR China"
            },
            {
                "name": "Langchong He",
                "org": ""
            }
        ],
        "venue": "Environmental toxicology and pharmacology",
        "year": 2011
    },
    "GFJsW0vd": {
        "id": "GFJsW0vd",
        "title": "Applications of HPLC/MS in the analysis of traditional Chinese medicines",
        "abstract": "In China,traditional Chinese medicines(TCMs)have been used in clinical applications for thousands of years.The successful hyphenation of high-performance liquid chromatography(HPLC)and mass spectrometry(MS)has been applied widely in TCMs and biological samples analysis.Undoubtedly,HPLC/MS technique has facilitated the understanding of the treatment mechanism of TCMs.We reviewed more than 350 published papers within the last 5 years on HPLC/MS in the analysis of TCMs.The present review focused on the applications of HPLC/MS in the component analysis,metabolites analysis,and pharmacokinetics of TCMs etc.50% of the literature is related to the component analysis of TCMs,which show that this field is the most popular type of research.In the metabolites analysis,HPLC coupled with electrospray ionization quadrupole time-of-flight tandem mass spectrometry has been demonstrated to be the powerful tool for the characterization of structural features and fragmentation behavior patterns.This paper presented a brief overview of the applications of HPLC/MS in the analysis of TCMs.HPLC/MS in the fingerprint analysis is reviewed elsewhere.",
        "keywords": [
            "traditional chinese medicines(tcms)",
            "metabolites analysis",
            "component analysis",
            "pharmacokinetics",
            "hplc/ms"
        ],
        "authors": [
            {
                "name": "miao li",
                "org": ""
            },
            {
                "name": "xiaofang hou",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "sicen wang",
                "org": ""
            },
            {
                "name": "qiang fu",
                "org": ""
            },
            {
                "name": "langchong he",
                "org": ""
            }
        ],
        "venue": "药物分析学报(英文版)",
        "year": 2011
    },
    "gujXzZCr": {
        "id": "gujXzZCr",
        "title": "Molecular Docking, 3D-QSAR Studies, and In Silico ADME Prediction of p-Aminosalicylic Acid Derivatives as Neuraminidase Inhibitors: Molecular Docking, 3D-QSAR Studies",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "yuanyuan shan",
                "org": ""
            },
            {
                "name": "xiaoyan pan",
                "org": ""
            },
            {
                "name": "chen wang",
                "org": ""
            },
            {
                "name": "wenfang xu",
                "org": ""
            },
            {
                "name": "langchong he",
                "org": ""
            }
        ],
        "venue": "Chemical Biology & Drug Design",
        "year": 2011
    },
    "LTHnrQWk": {
        "id": "LTHnrQWk",
        "title": "Synthesis and Anti-tumor Activities of Lactone Ring-Opened Taspine Coumarin Ester Fluorescent Derivatives",
        "abstract": "Using isovanillin as the starting material,the lactone ring-opened taspine derivative(compound 8) was obtained via bromination,benzylation,oxidation,Ulmman reaction and catalytic hydrogenation.Based on this,we designed and synthesized two novel lactone ring-opened taspine coumarin ester fluorescent derivatives with substituted coumarin(compounds 9a and 9b).The structures of the target compounds were characterized by means of IR,1H NMR and MS.The fluorescence and the anti-tumor activities of the target compounds were preliminarily examined.",
        "keywords": [
            "fluorescence",
            "anti-tumor activity",
            "coumarin",
            "taspine"
        ],
        "authors": [
            {
                "name": "HE Huaizhen",
                "org": "School of Medicine,Xi′an Jiaotong University,Xi′an "
            },
            {
                "name": "ZHAN Yingzhuan",
                "org": "School of Medicine,Xi′an Jiaotong University,Xi′an "
            },
            {
                "name": "ZHANG Jie",
                "org": "School of Medicine,Xi′an Jiaotong University,Xi′an "
            },
            {
                "name": "WANG Tao",
                "org": "School of Medicine,Xi′an Jiaotong University,Xi′an "
            }
        ],
        "venue": "Chinese Journal of Applied Chemistry",
        "year": 2012
    },
    "nqxBcjJ3": {
        "id": "nqxBcjJ3",
        "title": "Screening active compounds acting on the epidermal growth factor receptor from Radix scutellariae via cell membrane chromatography online coupled with HPLC/MS.",
        "abstract": "Radix scutellariae is a traditional Chinese medicine (TCM) and has many pharmacological effects, including antiviral, antibacterial, antifungal, antipyretic, hypotensive, anti-inflammatory and anti-anaphylaxis effects. However, few studies have screened the active compounds in this complex product for tumor therapy. In this study, a two-dimensional online method was developed to screen the active compounds from Radix scutellariae acting on the epidermal growth factor receptor. The screening results showed that wogonin from Radix scutellariae was the targeted component which acted on epidermal growth factor receptor specificity. The in vitro inhibitory activity of wogonin on the viability of cells with high epidermal growth factor receptor expression was tested using the MTT assay. In the dosage range of 0.40-50.0 μM, inhibition of HEK293/EGFR by wogonin was 8.94 ± 0.2, 20.64 ± 5.10, 34.16 ± 5.90 and 69.03 ± 7.80 at the concentrations of 0.4 × 10(-6), 2 × 10(-6), 10 × 10(-6) and 50 × 10(-6) molL(-1), respectively. These results showed that wogonin inhibited the growth of cells with high epidermal growth factor receptor expression in a dose-dependent manner.",
        "keywords": [
            "wogonin",
            "epidermal growth factor receptor",
            "radix scutellariae",
            "high performance liquid chromatography/mass spectrometry",
            "cell membrane chromatography"
        ],
        "authors": [
            {
                "name": "Huaizhen He",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Shengli Han",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Tao Zhang",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Sicen Wang",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Jingjing Hou",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            }
        ],
        "venue": "Journal of pharmaceutical and biomedical analysis",
        "year": 2012
    },
    "50hQMoXB": {
        "id": "50hQMoXB",
        "title": "A novel angiogenesis inhibitor impairs lovo cell survival via targeting against human VEGFR and its signaling pathway of phosphorylation",
        "abstract": "Colorectal cancer represents the fourth commonest malignancy, and constitutes a major cause of significant morbidity and mortality among other diseases. However, the chemical therapy is still under development. Angiogenesis plays an important role in colon cancer development.We developed HMQ18-22 (a novel analog of taspine) with the aim to target angiogenesis. We found that HMQ18-22 significantly reduced angiogenesis of chicken chorioallantoic membrane (CAM) and mouse colon tissue, and inhibited cell migration and tube formation as well. Then, we verified the interaction between HMQ18-22 and VEGFR2 by AlphaScreen P-VEGFR assay, screened the targets on angiogenesis by VEGF Phospho Antibody Array, validated the target by western blot and RNAi in lovo cells. We found HMQ18-22 could decrease phosphorylation of VEGFR2(Tyr1214), VEGFR1(Tyr1333), Akt(Tyr326), protein kinase Cα (PKCα) (Tyr657) and phospholipase-Cγ-1 (PLCγ-1) (Tyr771). Most importantly, HMQ18-22 inhibited proliferation of lovo cell and tumor growth in a human colon tumor xenografted model of athymic mice. Compared with normal lovo cells proliferation, the inhibition on proliferation of knockdown cells (VEGFR2, VEGFR1, Akt, PKCα and PLCγ-1) by HMQ18-22 decreased. These results suggested that HMQ18-22 is a novel angiogenesis inhibitor and can be a useful therapeutic candidate for colon cancer intervention. © 2012 Macmillan Publishers Limited. All rights reserved.",
        "keywords": [
            "angiogenesis",
            "hmq18-22",
            "inhibition",
            "signaling pathway",
            "vegfr",
            "cancer",
            " immunity",
            " neurodegeneration",
            " apoptosis",
            " cell death",
            " cell growth",
            " Stem Cell",
            " Signaling",
            " Autophagy",
            " Wallerian Degeneration",
            " Cornification",
            " Keratinization",
            " Toxicity",
            " Transcription"
        ],
        "authors": [
            {
                "name": "Yanmin Zhang",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Bingling Dai",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "LieRui Zheng",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Yingzhuan Zhan",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Wanli Wei Smith",
                "org": "University of Maryland, Baltimore(University of Maryland,U Maryland,University of Maryland Baltimore),Baltimore,United States"
            },
            {
                "name": "Xiaoli Wang",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Yule Chen",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Langchong He",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            }
        ],
        "venue": "Cell Death and Disease",
        "year": 2012
    },
    "xhgtLbQc": {
        "id": "xhgtLbQc",
        "title": "Synthesis of novel taspine diphenyl derivatives as fluorescence probes and inhibitors of breast cancer cell proliferation.",
        "abstract": "Two novel taspine diphenyl derivatives (Ta-dD) were designed and synthesized by introducing different coumarin fluorescent groups into the basic structure of Ta-dD. The main advantage of these two compounds is that they can be used as fluorescence probes and inhibitors simultaneously. In the present study, the fluorescent properties of the probes were measured and their inhibition of four breast cancer cell lines was tested. Different concentrations of the fluorescence probe were added to MCF-7 breast cancer cells for fluorescence imaging analysis under normal conditions. The results suggested that both of the new compounds have not only fluorescence but also the ability to inhibit effects on different breast cancer cell lines, which indicates their possible further use as dual functional fluorescence probes in tracer analysis.",
        "keywords": [
            "breast cancer cells",
            "fluorescence probe",
            "inhibitor",
            "taspine diphenyl derivatives"
        ],
        "authors": [
            {
                "name": "Huaizhen He",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Yingzhuan Zhan",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Yanmin Zhang",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Langchong He",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            }
        ],
        "venue": "Luminescence : the journal of biological and chemical luminescence",
        "year": 2012
    },
    "U1WvGDMJ": {
        "id": "U1WvGDMJ",
        "title": "ANovelTaspineDerivative,HMQ1611,InhibitsBreastCancer Cell Growth via Estrogen Receptor a and EGF Receptor Signaling Pathways",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "yingzhuan zhan",
                "org": ""
            },
            {
                "name": "yanmin zhang",
                "org": ""
            },
            {
                "name": "cuicui liu",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "wanli w smith",
                "org": ""
            },
            {
                "name": "nan wang",
                "org": ""
            },
            {
                "name": "yinnan chen",
                "org": ""
            },
            {
                "name": "lei zheng",
                "org": ""
            },
            {
                "name": "langchong he",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2012
    },
    "jIUJvL0E": {
        "id": "jIUJvL0E",
        "title": "Pharmacophore Modeling, 3D-QSAR Studies, and in-silico ADME Prediction of Pyrrolidine Derivatives as Neuraminidase Inhibitors: Pharmacophore Modeling, 3D-QSAR Studies",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "xiaoyan pan",
                "org": ""
            },
            {
                "name": "chen wang",
                "org": ""
            },
            {
                "name": "fang wang",
                "org": ""
            },
            {
                "name": "pengfei li",
                "org": ""
            },
            {
                "name": "wenfang xu",
                "org": ""
            },
            {
                "name": "langchong he",
                "org": ""
            }
        ],
        "venue": "Chemical Biology & Drug Design",
        "year": 2012
    },
    "aAl3vanA": {
        "id": "aAl3vanA",
        "title": "A novel taspine derivative, HMQ1611, inhibits breast cancer cell growth via estrogen receptor α and EGF receptor signaling pathways.",
        "abstract": "Breast cancer is a common cancer with a leading cause of cancer mortality in women. Currently, the chemotherapy for breast cancer is underdeveloped. Here, we report a novel taspine derivative, HMQ1611, which has anticancer effects using in vitro and in vivo breast cancer models. HMQ1611 reduced cancer cell proliferation in four human breast cancer cell lines including MDA-MB-231, SK-BR-3, ZR-75-30, and MCF-7. HMQ1611 more potently reduced growth of estrogen receptor α (ERα)-positive breast cancer cells (ZR-75-30 and MCF-7) than ERα-negative cells (MDA-MB-231 and SK-BR-3). Moreover, HMQ1611 arrested breast cancer cell cycle at S-phase. In vivo tumor xenograft model, treatment of HMQ1611 significantly reduced tumor size and weight compared with vehicles. We also found that HMQ1611 reduced ERα expression and inhibited membrane ERα-mediated mitogen-activated protein kinase (MAPK) signaling following the stimulation of cells with estrogen. Knockdown of ERα by siRNA transfection in ZR-75-30 cells attenuated HMQ1611 effects. In contrast, overexpression of ERα in MDA-MB-231 cells enhanced HMQ1611 effects, suggesting that ERα pathway mediated HMQ1611's inhibition of breast cancer cell growth in ERα-positive breast cancer. HMQ1611 also reduced phosphorylation of EGF receptor (EGFR) and its downstream signaling players extracellular signal-regulated kinase (ERK)1/2 and AKT activation both in ZR-75-30 and MDA-MB-231 cells. These results showed that the novel compound HMQ1611 had anticancer effects, and partially via ERα and/or EGFR signaling pathways, suggesting that HMQ1611 may be a potential novel candidate for human breast cancer intervention.",
        "keywords": [],
        "authors": [
            {
                "name": "Yingzhuan Zhan",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Yanmin Zhang",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Cuicui Liu",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Wanli W Smith",
                "org": "University of Maryland School of Pharmacy(University of Maryland School of Pharmacy,Univ. of Maryland School of Pharmacy,Univ. Maryland Sch. Pharm.),Baltimore,United States"
            },
            {
                "name": "Nan Wang",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Yinnan Chen",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Lei Zheng",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Langchong He",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            }
        ],
        "venue": "Cancer prevention research (Philadelphia, Pa.)",
        "year": 2012
    },
    "EsRzgmVp": {
        "id": "EsRzgmVp",
        "title": "Synthesis of novel taspine diphenyl derivatives as fluorescence probes and inhibitors of breast cancer cell proliferation: New fluorescence probes and labelled breast cancer cells",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "huaizhen he",
                "org": ""
            },
            {
                "name": "yingzhuan zhan",
                "org": ""
            },
            {
                "name": "yanmin zhang",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "langchong he",
                "org": ""
            }
        ],
        "venue": "Luminescence",
        "year": 2012
    },
    "PPavbLtY": {
        "id": "PPavbLtY",
        "title": "Design, synthesis, and vasorelaxation activity of novel imperatorin derivatives.",
        "abstract": "In this study, a series of novel imperatorin derivatives 7a-7e were designed and synthesized. Their vasorelaxation activities were evaluated by the pharmacological experiments in vitro. Most of the tested compounds exhibited better water solubility and vasorelaxation activity in different degrees, especially 7b and 7c with EC50 values of 2.29 and 2.63 μM, respectively on mesenteric artery, 7d and 7e with EC50 values of 1.04 and 2.65 μM, respectively on brain artery. The results indicated that these novel compounds have a potential interest for the development of novel and potent vasorelaxant agents for different kinds of arteries.",
        "keywords": [
            "synthesis",
            "xanthotoxol",
            "hypertension",
            "imperatorin",
            "vasorelaxation activity"
        ],
        "authors": [
            {
                "name": "Nan Zhou",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Jian-Yu He",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Tao Wang",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Huai-Zhen He",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            }
        ],
        "venue": "Journal of Asian natural products research",
        "year": 2013
    },
    "ndDHUiCp": {
        "id": "ndDHUiCp",
        "title": "Design, synthesis and biological evaluation of biphenyl urea derivatives as novel VEGFR-2 inhibitors",
        "abstract": "VEGFR-2 plays a critical role in vasculogenesis and VEGFR-2 inhibitors have been widely used in the treatment of cancer. In our continued efforts to search for potent and novel VEGFR-2 inhibitors as antitumor agents, we have identified a potent lead compound (HMQ-16) bearing a biphenyl scaffold. Rearrangement and replacement of arylcarbamoyl in HMQ-16 with a urea moiety generated a series of novel VEGFR-2 inhibitors. In order to enhance the affinity with VEGFR-2, the 4′-acetyl group was converted to an oxime group. Fourteen biphenyl urea derivatives were designed and synthesized as potent VEGFR-2 inhibitors. Six of them (T2, T5, T7, T9, T11, T14) exhibited potent VEGFR-2 inhibitory activity comparable to that of sorafenib. Compound T7 was the most potent with an IC 50 value of 1.08 nM. The enzymatic and cellular assays suggested that T7 has potential as a valuable lead compound for further optimization. © 2013 The Royal Society of Chemistry.",
        "keywords": [],
        "authors": [
            {
                "name": "Chen Wang",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Jinyun Dong",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Yanmin Zhang",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Fang Wang",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Hongping Gao",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Pengfei Li",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Sicen Wang",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            }
        ],
        "venue": "MedChemComm",
        "year": 2013
    },
    "2uBPWZ1V": {
        "id": "2uBPWZ1V",
        "title": "Effects of Filter Length and Ventilation on Transfer Behavior of Some Ester Flavors in Cigarette",
        "abstract": "In order to investigate the effects of filter length and ventilation on the transfer behavior of some ester flavors in cigarettes,the said ester flavors were injected into cigarettes with filters of various length and ventilation rates.These flavored cigarettes were stored airtightly for one week at temperature of 22 ℃±2 ℃ and relative humidity of 60%±5%,then analyzed by simultaneous distillation and extraction combined with GC and GC/MS.The relationships of flavor transfer ratio with filter length and ventilation rate were studied by multivariate analysis and multi-factor interaction stepwise regression analysis.The results showed that:1) The retention ratio in cut tobacco and transfer ratio into mainstream cigarette smoke of cinnamate flavors did not correlated with filter length and ventilation.2)If the flavor’s physical properties were neglected,filter length would be significantly negatively correlative with flavor’s retention ratio in cut tobacco,but significantly positively correlative with flavor’s transfer ratio into filter.Filter ventilation insignificantly correlated with flavor’s retention ratio in cut tobacco,while it weakly positively correlated with the transfer ratio into filter.3) The transfer ratios of ester flavors into mainstream cigarette smoke significantly negatively correlated with filter length and ventilation.",
        "keywords": [
            "Long filter",
            "Ester",
            "Flavor",
            "Ventilation and dilution",
            "Transfer behavior"
        ],
        "authors": [
            {
                "name": "ZHOU HUI-SHUN",
                "org": "Technology Center,China Tobacco Jiangxi Industrial Corporation,Nanchang ,China"
            },
            {
                "name": "ZONG YONG-LI",
                "org": "Zhengzhou Tobacco Research Institute of CNTC,Zhengzhou ,China"
            },
            {
                "name": "ZHANG JIE",
                "org": "Zhengzhou Tobacco Research Institute of CNTC,Zhengzhou ,China"
            },
            {
                "name": "PENG SHU-HAI",
                "org": "Zhengzhou Tobacco Research Institute of CNTC,Zhengzhou ,China"
            },
            {
                "name": "SONG YU-BING",
                "org": "Zhengzhou Tobacco Research Institute of CNTC,Zhengzhou ,China"
            }
        ],
        "venue": "Tobacco Science & Technology",
        "year": 2010
    },
    "YEoTKPk6": {
        "id": "YEoTKPk6",
        "title": "Transfer Behavior of Some Carbonyl Flavors in Filter and Tobacco Rod of Cigarette",
        "abstract": "Twelve carbonyl flavor samples were added into cut tobacco and filter tips of cigarettes and then analyzed by simultaneous distillation and extraction coupled with GC and GC/MS to determine the ratios of flavor retained in tobacco rod or filter,migrated to cut tobacco or filter and transferred into mainstream cigarette smoke.The results showed that:1) the retention ratios of the flavors injected into cut tobacco were lower than those added in filters,while their migration ratios from cut tobacco to filter were higher than those from filters to cut tobacco;2) filter flavoring facilitated the flavor with lower boiling point to transfer into cigarette mainstream smoke;3) the higher the boiling point,the greater the transfer ratio for isomeric carbonyl flavors,such as phenylacetaldehyde and acetophenone,caprylic aldehyde and 2-octanone,2-Heptanone,heptanal and 2,5-Hexanedione.",
        "keywords": [
            "Transfer ratio",
            "Carbonyl flavor",
            "Cigarette",
            "Migration ratio",
            "Retention ratio"
        ],
        "authors": [
            {
                "name": "ZHANG JIE",
                "org": "Zhengzhou Tobacco Research Institute of CNTC,Zhengzhou ,China"
            },
            {
                "name": "ZONG YONG-LI",
                "org": "Zhengzhou Tobacco Research Institute of CNTC,Zhengzhou ,China"
            },
            {
                "name": "ZHOU HUI-SHUN",
                "org": "Technology Center of China Tobacco Jiangxi Industrial Corporation,Nanchang ,China"
            },
            {
                "name": "PENG SHU-HAI",
                "org": "Zhengzhou Tobacco Research Institute of CNTC,Zhengzhou ,China"
            },
            {
                "name": "SONG YU-BING",
                "org": "Zhengzhou Tobacco Research Institute of CNTC,Zhengzhou ,China"
            }
        ],
        "venue": "Tobacco Science & Technology",
        "year": 2011
    },
    "dEZe4mko": {
        "id": "dEZe4mko",
        "title": "In vitro Test of Nicotine Release from Bagged Oral Smokeless Tobacco Products",
        "abstract": "A device for simulating nicotine release from oral smokeless tobacco product in human mouth was developed,which consisted of a container for solvent,a constant flow pump,a constant temperature trough,a pre-heating coil,a thermostatic tube,a thermostatic cell,and a liquid collector.The thermostatic cell acted as a buccal cavity to ensure nicotine to be released in the cell under a constant temperature of 37 ℃.The device was convenient in operation and good in stability and could effectively simulate nicotine release behavior of oral smokeless tobacco products and distinguish the difference of nicotine release between different products.The novel technique is suitable for quality evaluation,and nicotine level control of oral smokeless tobacco products as well as the assessment of bioavailability of nicotine.",
        "keywords": [
            "Oral smokeless tobacco product",
            "Nicotine",
            "In vitro release",
            "Release device"
        ],
        "authors": [
            {
                "name": "ZHANG JIE",
                "org": "Zhengzhou Tobacco Research Institute of CNTC,Zhengzhou ,China"
            },
            {
                "name": "LI PENG",
                "org": "Zhengzhou Tobacco Research Institute of CNTC,Zhengzhou ,China"
            },
            {
                "name": "PENG SHU-HAI",
                "org": "Zhengzhou Tobacco Research Institute of CNTC,Zhengzhou ,China"
            },
            {
                "name": "ZONG YONG-LI",
                "org": "Zhengzhou Tobacco Research Institute of CNTC,Zhengzhou ,China"
            },
            {
                "name": "SUN SHI-HAO",
                "org": "Zhengzhou Tobacco Research Institute of CNTC,Zhengzhou ,China"
            },
            {
                "name": "QIAN FA-CHENG",
                "org": "Zhengzhou Tobacco Research Institute of CNTC,Zhengzhou ,China"
            },
            {
                "name": "XIE JIAN-PING",
                "org": "Zhengzhou Tobacco Research Institute of CNTC,Zhengzhou ,China"
            }
        ],
        "venue": "Tobacco Science & Technology",
        "year": 2011
    },
    "2XU3vcKU": {
        "id": "2XU3vcKU",
        "title": "Simultaneous Determination of 1,2-Propylene Glycol,Glycerol and Triethylene Glycol in Smokeless Tobacco Products by Gas Chromatography-Mass Spectrometry",
        "abstract": "A gas chromatography-mass spectrometry(GC/MS) method under selected i on monitoring(SIM) mode was developed for the simultaneous determination of 1, 2-propylene glycol,glycerol and triethylene glycol in smokeless tobacco produc t s(STPs) by using 1,4-butanediol as an internal standard.Thirty STP samples w e re parallel tested by GC/MS/SIM and GC/FID,a CORESTA recommended method,and th e results were compared.The results showed that: 1) The recoveries of 1,2-pro p ylene glycol,glycerol and triethylene glycol ranged from 89.3% to 100.3% with the limits of detection of 1.25 to 2.75 μg/g and RSDs of 1.16 % to 4.37%.2) Th e contents of 1,2-propylene glycol,glycerol,and triethylene glycol in the sa mp les ranged from 0.011 to 40.817,0.024 to 39.044,0.012 to 0.099 mg/g,respectiv ely.3) 1,2-propylene glycol in 13 samples and glycerol in 14 samples were det e cted,and their contents in 9 of the samples were accurately determinable,howev er,triethylene glycol was undetectable in all samples by GC/FID.4) 1,2-propy l ene glycol in 29 samples,glycerol in 28 samples and triethylene glycol in 21 sa mples were detected,their contents in 16,25 and 11 of the samples could be acc urately determined by GC/MS/SIM method,respectively.5) The Pearson correlation coefficients between the contents of 1,2-propylene glycol in 13 samples and g l ycerol in 9 samples determined by GC/FID and GC/MS/SIM were over 0.99 probable v alue less than significant level of 0.05 and paired test t value over significan t level of 0.05.It was concluded that the target analytes in the samples determ ined by GC/MS/SIM agreed with those by GC/FID,however,GC/MS/SIM method was mor e sensitive and accurate.GC/MS/SIM method is more suitable for the qualitative and quantitative determination of 1,2-propylene glycol,glycerol,and triethyl ene glycol in smokeless tobacco products.",
        "keywords": [
            "1",
            "Glycerol",
            "Gas chromatography-mass spectrometry(GC/MS)",
            "2-Propylene glycol",
            "Smokeless tobacco produ cts",
            "Triethylene glycol"
        ],
        "authors": [
            {
                "name": "ZHANG JIE",
                "org": ",and ZONG YONG LI Zhengzhou Tobacco Research Institute of China National Tobacco Corporation,Zhen gzhou ,China"
            },
            {
                "name": "LI PENG",
                "org": ",and ZONG YONG LI Zhengzhou Tobacco Research Institute of China National Tobacco Corporation,Zhen gzhou ,China"
            },
            {
                "name": "SUN SHI-HAO",
                "org": ",and ZONG YONG LI Zhengzhou Tobacco Research Institute of China National Tobacco Corporation,Zhen gzhou ,China"
            },
            {
                "name": "SONG YU-BING",
                "org": ",and ZONG YONG LI Zhengzhou Tobacco Research Institute of China National Tobacco Corporation,Zhen gzhou ,China"
            },
            {
                "name": "XIE JIAN-PING",
                "org": ",and ZONG YONG LI Zhengzhou Tobacco Research Institute of China National Tobacco Corporation,Zhen gzhou ,China"
            }
        ],
        "venue": "Tobacco Science & Technology",
        "year": 2011
    },
    "GD3MsxsS": {
        "id": "GD3MsxsS",
        "title": "Analysis of Total Nicotine,Free Nicotine and Tobacco-specific N-nitrosamines in Foreign Oral Smokeless Tobacco Products",
        "abstract": "The moisture content,nicotine,pH,free nicotine,and 4 tobacco-specific nitrosamines(TSNAs) in 65 samples of foreign oral smokeless tobacco products were analyzed with CORESTA recommended methods.The results showed that there was wide discrepancy among these samples;moisture content and pH ranged from 12.07% to 55.58% and 5.55 to 8.98,respectively;on the basis of total wet weight,the contents of nicotine and free nicotine were in the range of 5.41-27.68 and 0.63-10.46 mg/g,respectively;the release rate of free nicotine was 7.8%-72.3%;the total content of 4 TSNAs was 0.54-31.91 μg/g,the contents of NNN,NNK,NAT,and NAB were 0.31-17.00,0.07-6.00,0.11-6.51,and 0.01-2.54 μg/g,respectively.",
        "keywords": [
            "Oral smokeless tobacco product",
            "Nicotine",
            "Tobacco-specific N-nitrosamines"
        ],
        "authors": [
            {
                "name": "ZHANG JIE",
                "org": "Zhengzhou Tobacco Research Institute of CNTC,Zhengzhou ,China;Beijing Workstation,Technology Center,Shanghai Tobacco%%#Group%%# Co.,Ltd.,Beijing ,China"
            },
            {
                "name": "LI PENG",
                "org": "Zhengzhou Tobacco Research Institute of CNTC,Zhengzhou ,China"
            },
            {
                "name": "ZONG YONG-LI",
                "org": "Zhengzhou Tobacco Research Institute of CNTC,Zhengzhou ,China"
            },
            {
                "name": "SUN SHI-HAO",
                "org": "Zhengzhou Tobacco Research Institute of CNTC,Zhengzhou ,China"
            },
            {
                "name": "WANG SHENG",
                "org": "Zhengzhou Tobacco Research Institute of CNTC,Zhengzhou ,China"
            },
            {
                "name": "XIE JIAN-PING",
                "org": "Zhengzhou Tobacco Research Institute of CNTC,Zhengzhou ,China"
            }
        ],
        "venue": "Tobacco Science & Technology",
        "year": 2011
    },
    "tT1OioFK": {
        "id": "tT1OioFK",
        "title": "Effect of Heat Treatment Process on Microstructure and Mechanical Properties of F550 Ship Plate Steel",
        "abstract": "The effect of the different heat treatment processes on microstructure and the mechanical properties of a 60mm thick F550 ship plate steel which was produced by controlled rolling and cooling process was studied by utilizing optical microscope and the mechanical properties tests.The results show that after being treated by the two-phase region quenching and tempering,the steel has better mechanical properties,especially significantly higher low-temperature toughness compared to that by complete quenching and tempering.Complete quenching and tempering obtained single bainite,while intercritical heat treatment obtained the bainite and fine-grained ferrite two-phase structure.",
        "keywords": [
            "intercritical heat treatment",
            "low-temperature toughness",
            "ship plate steel"
        ],
        "authors": [
            {
                "name": "LI Xiao-lin",
                "org": "Engieering Research Institute,University of Science and Technology Beijing,Beijng ,China"
            },
            {
                "name": "YU Wei",
                "org": "Engieering Research Institute,University of Science and Technology Beijing,Beijng ,China"
            },
            {
                "name": "WAN De-cheng",
                "org": "Engieering Research Institute,University of Science and Technology Beijing,Beijng ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Engieering Research Institute,University of Science and Technology Beijing,Beijng ,China"
            },
            {
                "name": "WU Hui-bin",
                "org": "Engieering Research Institute,University of Science and Technology Beijing,Beijng ,China"
            },
            {
                "name": "CAI Qing-wu",
                "org": "Engieering Research Institute,University of Science and Technology Beijing,Beijng ,China"
            }
        ],
        "venue": "Journal of Iron and Steel Research",
        "year": 2011
    },
    "KjZ5lqIK": {
        "id": "KjZ5lqIK",
        "title": "Effect of quenching temperature on microstructure and low temperature toughness of high strength offshore plateform steel",
        "abstract": "Effect of quenching temperature on microstructure and low temperature toughness of high strength offshore plateform steel was researched. The results show that austenite net which generated at the boundarys of granular bainite when heated and holded at 760 °C transformed to twin martensite after quenching, twin martensite resolved during tempering process, it will do harm to low teperature toughness. Austenite generated at 790 °C heating and holding transformed to bainite after quenching, which has strong stability in tempering process. Granular bainite which not transformed to austenite during heating process undergoes recrystallization, and forms many polygonal ferrites which help for low temperature toughness.",
        "keywords": [
            "High strength steel",
            "Low temperature toughness",
            "Microstructure",
            "Quenching"
        ],
        "authors": [
            {
                "name": "Zhiqiang Cao",
                "org": "University of Science and Technology Beijing(University of Science and Technology Beijing),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "University of Science and Technology Beijing(University of Science and Technology Beijing),Beijing,China"
            },
            {
                "name": "Huibin Wu",
                "org": "University of Science and Technology Beijing(University of Science and Technology Beijing),Beijing,China"
            },
            {
                "name": "Yanping Bao",
                "org": "University of Science and Technology Beijing(University of Science and Technology Beijing),Beijing,China"
            }
        ],
        "venue": "Jinshu Rechuli/Heat Treatment of Metals",
        "year": 2012
    },
    "Us3cX4qq": {
        "id": "Us3cX4qq",
        "title": "Effect of quenching temperature and tempering on low-temperature toughness of a F550 ship plate steel",
        "abstract": "Microstructure and mechanical properties of F550 ship plate steel after guenching at 820 ℃,850 ℃,910 ℃ and tempering at 600 ℃ were investigared.The effects of quenching temperature on low temperature toughness of F550 ship plate steel were examined.The morphology,size and distribution of martensite-austenite(M/A) constituents and the volume fraction of M/A islands and polygonal ferrite obtained after different heat treatment processes were observed by optical microscope,scanning electron microscopy(SEM),transmission electron microscopy(TEM) and quantitative metallographic methods.The results show that after intercritical quenching at 850 ℃ and tempering at 600℃,the low temperature toughness at-80 ℃ of the steel is the best,which is about 220 J.After complete quenching at 910 ℃ and tempering at 600 ℃,the main microstructure of the steel is bainite,and the amount of M/A islands with the size above 2 μm increases and the M/A islands are distributed at grain boundaries or between bainitic ferrite lathes with the form of elongated block and dots,which lead to the decrease of toughness.After sub-critical heat treatment,the microstructure consists of polygonal ferrite(QF) and granular bainite,and polygonal ferrite is fine and distributed uniformly.The amount of M/A islands is smaller compared with that of complete quenching and tempering,and the M/A islands with dot-shape disperse uniformly between bainitic ferrite lathes acting as effective barriers to crack propagation.",
        "keywords": [
            "Bainite",
            "Low temperature toughness",
            "M/A island",
            "Polygonal ferrite",
            "Sub-temperature quenching"
        ],
        "authors": [
            {
                "name": "LI Xiao-lin",
                "org": "Engineering Research Institute,University of Science and Technology Beijing,Beijing ,China"
            },
            {
                "name": "YU Wei",
                "org": "Engineering Research Institute,University of Science and Technology Beijing,Beijing ,China"
            },
            {
                "name": "ZHU Ai-ling",
                "org": "Nanjing Iron & Steel Co Ltd,Product Development Center,Nanjing ,China"
            },
            {
                "name": "WU Hui-bin",
                "org": "Engineering Research Institute,University of Science and Technology Beijing,Beijing ,China"
            },
            {
                "name": "WAN De-cheng",
                "org": "Engineering Research Institute,University of Science and Technology Beijing,Beijing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Engineering Research Institute,University of Science and Technology Beijing,Beijing ,China"
            }
        ],
        "venue": "Transactions of Materials and Heat Treatment",
        "year": 2012
    },
    "gzMVJLfw": {
        "id": "gzMVJLfw",
        "title": "Atmospheric Corrosion Resistance of EH36 Ocean Platform Steel",
        "abstract": "The atmospheric corrosion behaviors of three kinds of EH36 ocean platform steels with different compositions were investigated by cyclic wet-dry corrosion experiments.The results showed that the rust layer tended to be more compact by lowering C content and increasing Cr content.Protective corrosion products goethite(α-FeOOH) and lepidocrocite(γ-FeOOH) were the major constituents of the rust.The corrosion products can inhibit the increase of corrosion rates significantly during the later stage of corrosion.",
        "keywords": [
            "atmospheric corrosion",
            "corrosion product",
            "ocean platform steel"
        ],
        "authors": [
            {
                "name": "TANG Di",
                "org": "Research Institute of Metallurgy Engineering,Beijing University of Science and Technology,Beijing "
            },
            {
                "name": "ZHANG Ming-jie",
                "org": "Research Institute of Metallurgy Engineering,Beijing University of Science and Technology,Beijing "
            },
            {
                "name": "WU Hui-bin",
                "org": "Research Institute of Metallurgy Engineering,Beijing University of Science and Technology,Beijing "
            },
            {
                "name": "ZHANG Jie",
                "org": "Research Institute of Metallurgy Engineering,Beijing University of Science and Technology,Beijing "
            }
        ],
        "venue": "Corrosion & Protection",
        "year": 2012
    },
    "jeENFriW": {
        "id": "jeENFriW",
        "title": "Effect of quenching temperature on microstructure and properties of E550 ocean engineering steel",
        "abstract": "The TMCP 60 mm thick E550 ocean engineering steel plates were quenched at 860°C, 890°C and 930°C respectively and then tempered at 650°C, after that, the microstructure and mechanical properties of the steel plates was investigated by SEM and EBSD. The results show that with the increasing of quenching temperature, the yield strength of the steel plates is increased, while the tensile strength and elongation remain unchanged mainly. After quenching at 860°C and tempering at 650°C, the steel plate has fine and homogeneous microstructure and lots of small angle grain boundaries with good impact toughness; when the quenching temperature is increased to 890°C, grain size is increased and large angle grain boundaries are dominated; when the quenching temperature is increased to 930°C, neighbouring austenite grains grow and combine, therefore the impact toughness is deteriorated, the lowest value is 20 J.",
        "keywords": [
            "Electron backscattered diffraction (EBSD)",
            "Grain boundary",
            "Heat treatment",
            "Low carbon bainitic",
            "Ocean engineering steel",
            "TMCP"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "University of Science and Technology Beijing(University of Science and Technology Beijing),Beijing,China"
            },
            {
                "name": "Qingwu Cai",
                "org": "University of Science and Technology Beijing(University of Science and Technology Beijing),Beijing,China"
            },
            {
                "name": "Huibin Wu",
                "org": "University of Science and Technology Beijing(University of Science and Technology Beijing),Beijing,China"
            },
            {
                "name": "HongBao Zhou",
                "org": "University of Science and Technology Beijing(University of Science and Technology Beijing),Beijing,China"
            },
            {
                "name": "JIANG Jinxing",
                "org": "University of Science and Technology Beijing(University of Science and Technology Beijing),Beijing,China"
            }
        ],
        "venue": "Jinshu Rechuli/Heat Treatment of Metals",
        "year": 2012
    },
    "xWDfJHRa": {
        "id": "xWDfJHRa",
        "title": "Effect of Quenching Temperature on Microstructure and Properties of E690 Offshore Platform Steel",
        "abstract": "TMCP 60 mm thickness E690 offshore plateform steel plates were quenched at 730,760,790,820,850,880 and 910℃,respectively.The microstructure was investigated by scanning electron microscope and transmission electron microscope.The results show that when heat preserved at 730℃,the austenite generates at the boundary of granular bainite firstly,tiny austenite islands distributes along with the grain boundary;heat preserved at 760℃,the austenite islands along with grain boundary becomes merging,heat preserved at 790℃,austenite looks like net along with grain boundary and also generates at inner grain meanwhile;with the increase of quenching temperature to 820℃,the austenite size is in 1-3μm.The granular bainite which not transformed into austenite produces relaxation and recrystallization.The martensite/austenite islands inner granular bainite resolves continually and disappears during heating process.",
        "keywords": [
            "low carbon bainitic",
            "offshore plateform",
            "heat treatment"
        ],
        "authors": [
            {
                "name": "CAO Zhiqiang",
                "org": "Research Institute of Metallurgy Engineering,University of Science and Technology Beijing,Beijing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Research Institute of Metallurgy Engineering,University of Science and Technology Beijing,Beijing ,China"
            },
            {
                "name": "WU Huibin",
                "org": "Research Institute of Metallurgy Engineering,University of Science and Technology Beijing,Beijing ,China"
            },
            {
                "name": "BAO Yanping",
                "org": "Research Institute of Metallurgy Engineering,University of Science and Technology Beijing,Beijing ,China"
            }
        ],
        "venue": "Hot Working Technology",
        "year": 2012
    },
    "VrAe78Aa": {
        "id": "VrAe78Aa",
        "title": "Mechanical properties and marine atmosphere corrosion behavior of E690 ocean platform steel",
        "abstract": "Compared with E36 ocean platform steel, the microstructures and mechanical properties of three kinds of E690 ocean platform steels were studied as well as their corrosion behavior in simulating marine atmosphere. The corrosion rates during different periods were measured by the weight-loss method, the morphology and microstructure of the surface corrosion products were analyzed by scan electron microscopy and X-ray diffraction, and the grain boundaries were examined through electron backscattered diffraction. E690 platform steels consisting of bainite demonstrate outstanding mechanical properties and their impact values at -40°C exceed 200 J. The majority of grain boundaries are sub-grain boundaries in a range from 3° to 15° and high angle grain boundaries surpassing 50°. The minimum corrosion rate of E690 ocean platform steels after 16 d is 0.84 mm·a -1, which is far below 1.4 mm·a -1 of ferrite + pearlite steels. The corrosion rates also tend to stabilize due to a compact rust layer. The rust layer consists of Fe 3O 4, α-FeOOH, β-FeOOH, γ-FeOOH and amorphous substances. It is revealed that the heat treatment and microstructure play an important role in the corrosion behavior during the earlier stage, but the chemical composition and density of the rust layer influence the corrosion behavior greatly in the later stage.",
        "keywords": [
            "Atmospheric corrosion",
            "Bainite",
            "Drilling platforms",
            "Grain boundaries",
            "Low carbon steel",
            "Seawater corrosion"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "University of Science and Technology Beijing(University of Science and Technology Beijing),Beijing,China"
            },
            {
                "name": "CAI Qing-wu",
                "org": "University of Science and Technology Beijing(University of Science and Technology Beijing),Beijing,China"
            },
            {
                "name": "WU Hui-bin",
                "org": "University of Science and Technology Beijing(University of Science and Technology Beijing),Beijing,China"
            },
            {
                "name": "FAN Xue-hua",
                "org": "China Petroleum Engineering Co. Ltd. Beijing Branch(Beijing Branch of China Petroleum Engineering Co., Ltd.,China Petroleum Engineering Co. Ltd. Beijing Branch,Beijing Branch of China Petroleum Engineering Co. Ltd.),Beijing,China"
            },
            {
                "name": "ZHANG Ming-jie",
                "org": "University of Science and Technology Beijing(University of Science and Technology Beijing),Beijing,China"
            }
        ],
        "venue": "Beijing Keji Daxue Xuebao/Journal of University of Science and Technology Beijing",
        "year": 2012
    },
    "oXzyAdqj": {
        "id": "oXzyAdqj",
        "title": "Temperature distribution measurement of high energetic monopropellant by spectroscopic diagnostic technology]",
        "abstract": "The combustion flame temperature distribution in the axes are measured by relative intensity method of the spectroscopic diagnostic technology for monopropellant hexanitrohexaazaisowurtzitane (HNIW) at 3 MPa and 5 MPa pressure, respectively. The investigation results show that the curves of combustion flame temperature distribution in all combustion course are accurately measured by relative intensity method for monopropellant HNIW. The measured highest combustion flame temperature in the axes are lower than theoretical combustion temperature at the same pressure, and are more close to theoretical combustion temperature along with the rising of the pressure. The experimental results indicate that the combustion flame temperature distribution can be measured by the relative intensity method for high energetic and high burning rate propellant at higher pressure.",
        "keywords": [],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Institute of Nuclear Energy Technology, Tsinghua University, Beijing 100084, China."
            },
            {
                "name": "Yan-wen Zou",
                "org": ""
            },
            {
                "name": "Jun He",
                "org": ""
            },
            {
                "name": "Rong-jie Yang",
                "org": ""
            },
            {
                "name": "Wen-hua Zhao",
                "org": ""
            },
            {
                "name": "Zhong-yan Fang",
                "org": ""
            }
        ],
        "venue": "Guang pu xue yu guang pu fen xi = Guang pu",
        "year": 2004
    },
    "epO10PBa": {
        "id": "epO10PBa",
        "title": "Surface modification of solid particles and its application in propellants fields",
        "abstract": "Surface modification for solid particles component such as oxidizers and fuels in a formula for propellant can not only improve usable properties of single component, but also can increase mechanical properties and improve combustion properties and technical conditions of propellant. The method of surface modification for solid particles and token of the modified solid particles are summarized, then change of coated particles properties and its influence on properties of propellant are analyzed in this paper.",
        "keywords": [
            "Coating",
            "Propellant",
            "Sensitivity",
            "Surface modification"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Tsinghua University(Tsinghua University,Tsinghua Univ,Tsinghua Univ.),Beijing,China"
            },
            {
                "name": "Jun He",
                "org": "Tsinghua University(Tsinghua University,Tsinghua Univ,Tsinghua Univ.),Beijing,China"
            },
            {
                "name": "Yanwen Zou",
                "org": "Tsinghua University(Tsinghua University,Tsinghua Univ,Tsinghua Univ.),Beijing,China"
            }
        ],
        "venue": "Harbin Gongye Daxue Xuebao/Journal of Harbin Institute of Technology",
        "year": 2004
    },
    "cZ0xa3Hc": {
        "id": "cZ0xa3Hc",
        "title": "Study of a composite bipolar plate for PEMFC",
        "abstract": "The influences of the different conductive fillers (graphite), resins, pressures and temperature on the properties of resin/graphite composite PEMFC bipolar plates were investigated. Results show that the components of conductive filler, and the sort and content of resin have a larger effect on the composite properties than do the pressure and temperature. Bipolar plates using a mixture of natural graphite and electrographite as conductive filler are better than that using a single component. The resin content, molding pressures and temperature should be 16-18 w/%, 10-20 MPa and 150-200°C, respectively. The composite bipolar plates obtained have a conductivity over 300 S/cm, a flexural strength over 30MPa and a permeability of 10-7 cm2/s.",
        "keywords": [
            "Bipolar plate",
            "Composite materials",
            "Fuel cell"
        ],
        "authors": [
            {
                "name": "Yanwen Zou",
                "org": "Tsinghua University(Tsinghua University,Tsinghua Univ,Tsinghua Univ.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Tsinghua University(Tsinghua University,Tsinghua Univ,Tsinghua Univ.),Beijing,China"
            },
            {
                "name": "Jun He",
                "org": "Tsinghua University(Tsinghua University,Tsinghua Univ,Tsinghua Univ.),Beijing,China"
            },
            {
                "name": "Yongping Zheng",
                "org": "Tsinghua University(Tsinghua University,Tsinghua Univ,Tsinghua Univ.),Beijing,China"
            },
            {
                "name": "Yaping Tang",
                "org": "Tsinghua University(Tsinghua University,Tsinghua Univ,Tsinghua Univ.),Beijing,China"
            },
            {
                "name": "Bin Sun",
                "org": "Tsinghua University(Tsinghua University,Tsinghua Univ,Tsinghua Univ.),Beijing,China"
            },
            {
                "name": "Xueliang Qiu",
                "org": "Tsinghua University(Tsinghua University,Tsinghua Univ,Tsinghua Univ.),Beijing,China"
            }
        ],
        "venue": "Xinxing Tan Cailiao/New Carbon Materials",
        "year": 2004
    },
    "GAOyCGCK": {
        "id": "GAOyCGCK",
        "title": "Calculation and Analysis on Energy Characteristics of AN-based Propellants",
        "abstract": "The effect of oxidizers (HNIW, AP and HMX) and binders (BAMO, GAP, PET and HTPB) on energy characteristics of the AN-based propellants is investigated by the least free energy method. Results show that high energy compound HNIW to increase energy level of the AN-based propellants is always not higher than that of other two oxidizers. The amplitude of HNIW to increase the specific impulse of the AN-based propellants is higher than that of HMX, and less than that of AP when the content of binder is equal to 15%,however the amplitude of HNIW to increase the specific impulse of the AN-based propellants is higher than that of HMX and AP when the content of binder is equal to 5%. Non-energetic binders benefit increasing energy of the AN-based propellants in lower content (<12%)binder system, but energetic binders benefit increasing energy of the AN-based propellants in higher content(>13%)binder system. GAP is more beneficial to increasing energy better than BAMO, and every binder all exists a optimum addition amount.",
        "keywords": [
            "binder",
            "low signature sign",
            "ammonium nitrate(AN)",
            "specific impulse",
            "propellant",
            "physical chemistry"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Institute of Nuclear Energy and New Energy Technology, Tsinghua University, Beijing , China"
            },
            {
                "name": "HE Jun",
                "org": "Institute of Nuclear Energy and New Energy Technology, Tsinghua University, Beijing , China"
            }
        ],
        "venue": "Energetic Materials",
        "year": 2005
    },
    "fHf923UQ": {
        "id": "fHf923UQ",
        "title": "A study of the air permeation for the composite material bipolar plates of PEMFC",
        "abstract": "Composite material bipolar plates using thermoplastic resin as the binder and graphite as the conductive filler were prepared by means of compression molding technology.The influences of the resin content and molding parameter on the air permeation of bipolar plates were researched.The results showed the influences of content of resin and the molding pressure on the air permeation of bipolar plates were bigger than that of the molding temperature and temperature keeping time on it.The air permeation rate could reach the order of magnitute of 10~(-12) cm/s·Pa when the resin content was 10%～16%,molding temperature was 5～25 MPa,molding temperature was 140～170 ℃ and temperature keeping time was 10～40 min.",
        "keywords": [
            "composite materials",
            "bipolar plates",
            "air permeation rate"
        ],
        "authors": [
            {
                "name": "ZOU Yan-wen",
                "org": "Institute of Nuclear and New Energy Technology,Tsinghua University,Beijing ,China"
            },
            {
                "name": "SUN Bin",
                "org": "Institute of Nuclear and New Energy Technology,Tsinghua University,Beijing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Institute of Nuclear and New Energy Technology,Tsinghua University,Beijing ,China"
            },
            {
                "name": "HE Jun",
                "org": "Institute of Nuclear and New Energy Technology,Tsinghua University,Beijing ,China"
            },
            {
                "name": "WU Bing",
                "org": "Beijing LN Power Sources Co.,Ltd.,Beijing ,China"
            }
        ],
        "venue": "Battery Bimonthly",
        "year": 2006
    },
    "V3FQl70Z": {
        "id": "V3FQl70Z",
        "title": "Manufacture and characteristics of spherical fuel elements for the HTR-10",
        "abstract": "The R&D of spherical fuel elements for the 10 MW high temperature gas-cooled reactor (HTR-10) started in 1986 in China. A process known as cold quasi-isostatic molding was used for manufacturing spherical fuel elements, and about 20,540 spherical fuel elements were produced in 2000 and 2001. Fabrication technology and graphite matrix materials were investigated and optimized. Cold properties of the spherical fuel elements met the design specifications. The mean free uranium fraction of 44 batches was 4.57 × 10 −5 . In-pile irradiation test results showed that irradiation did not lead to apparent change in linear dimensional, geometrical density, porosity and strength of matrix graphite samples. No cracks and blisters were observed in spherical fuel elements. This indicated that matrix graphite and spherical fuel elements of HTR-10 met the requirement of design specifications. 1 Introduction Research and development of high temperature gas-cooled reactor (HTGR) fuel elements in China started from the middle of 1970s and have been enhanced since the China High Technology Program was put into effect in 1986. The HTR-10 constructed in China reached first criticality successfully in December 2000, and realized full power operation in the beginning of 2003. All-ceramic spherical fuel elements are used in the HTR-10. Spherical fuel elements 60 mm in diameter are composed of a fuel zone with a diameter of 50 mm and a fuel-free shell with a thickness of 5 mm. About 8300 TRISO coated fuel particles are homogeneously dispersed in the graphite matrix of the fuel zone. Graphite matrix, as a structural material, has to perform a series of tasks in the fuel element. Therefore, it should have suitable physical–chemical properties, which include: (1) nuclear-grade, impurities can decrease the corrosion resistance and other performances of fuel elements; (2) high density, density is an important parameter as a moderator, and it also has influence on mechanical strength. The design density of graphite matrix is larger than 1.70 g cm −3 ; (3) high thermal conductivity, the graphite matrix should have a high thermal conductivity so as to transfer fission heat from coated fuel particles to the outer surface of fuel elements; (4) high mechanical strength, fuel elements are subjected various external forces, for instance, spherical fuel elements fall onto the pebble bed when they are loaded into the reactor core. Fuel elements should have high mechanical strength to endure various external mechanical loads, irradiation stress and thermal stress, while keeping their integrity; (5) good corrosion resistance, various active impurities, such as H 2 O, O 2 , O, CO 2 , etc. present in helium coolant under normal condition, and accidental air or water ingress into the primary circuit can result in chemical oxidation of the graphite matrix; (6) good irradiation performance. Two types of graphite matrix materials, A3–3 standard matrix and A3–27 matrix with synthesized resin molded by cold quasi-isostatic molding, were used for manufacturing fuel elements for AVR and THTR in Germany ( Schulze et al., 1981; Mehner et al., 1990 ). Hot molding of spherical fuel elements was also developed in order to increase heavy metal loading ( Delle et al., 1985 ). Methods based on carbonization under pressure (CUP) ( Chernikov et al., 1991 ) of molded roughcast spherical fuel elements and volume gas-phase impregnations ( Zelenskij et al., 1991 ) of porous media with pyrocarbon were developed in the former USSR. Cold quasi-isostatic molding was chosen for manufacturing the spherical fuel elements for HTR-10 in China ( Tang et al., 2002 ). 2 Manufacturing technology for spherical fuel elements A schematic diagram of the manufacturing process for HTR-10 spherical fuel elements is shown in Fig. 1 . The process mainly consists of the following steps: manufacture of the graphite matrix powder, overcoating of coated particles (CP), cold quasi-isostatic molding and heat treatment. 2.1 Manufacture of graphite matrix powder The graphite matrix powder was composed of natural graphite, electrographite and resin in a certain proportion. In the traditional manufacturing process, coke was used as the aggregate and the final graphite temperature was higher than 2500 °C. However, the highest treatment temperature should not be higher than 2000 °C, far lower than the graphitization temperature of coke. If the coke was treated at a temperature of lower than 2000 °C, the matrix could not be graphitized, resulting in a decrease of irradiation resistance, thermal conductance, mechanical strength, corrosion resistance, etc. Choosing a mixture of natural graphite and electrographite as the aggregate can avoid the high temperature graphitization process and the matrix has a high degree of graphitization. In HTR-10, natural graphite and electrographite are used as filler components, and natural graphite is the main component of the graphite matrix. Ordinary natural flake graphite from Beishu Graphite Mine (Shandong Province, China) was purified before being used as raw materials for the graphite matrix by means of a wet chemical process using hydrofluoric acid, hydrochloric acid and sulfuric acid as leaching reagents. The content of ash, lithium and boron equivalent are about 100, <0.005 and <1 ppm, respectively. Particle sizes of raw materials can influence the molding characteristics of graphite matrix materials, as well as the quality and irradiation performance of spherical fuel elements. Natural graphite and electrographite used in HTR-10 were crushed to a suitable size distribution, listed in Table 1 , by a hammer mill. The two filler components, natural graphite and electrographite are pre-mixed, kneaded with the dissolved phenolic resin binder, dried under vacuum at 100 °C, and ground in a hammer mill with a sieve of 1 mm. The molding characteristics of the mixtures (carbonization at 800 °C) with different ratios of natural graphite and electrographite were researched. The compression of electrographite powder was difficult. The density of the roughcast with electrographite powder and resin binder was very low even though it was compacted at relatively high pressure. Correspondingly, the compression of natural graphite powder was easy. High density (1.8–2.0 g/cm 3 ), crack-free roughcast with natural graphite and resin binder could be obtained. However, too high pressure could result in cracking during the carbonization process. The results showed that the suitable mix-ratio of electrographite and natural graphite ranges from 1:4 to 1:6, which was consistent with the report of German scientists and engineers ( Schulze et al., 1981 ). In the manufacture of HTR-10 fuel elements, the mix-ratio of the graphite matrix made from the raw materials was 64 wt% natural flake graphite, 16 wt% electrographite and 20 wt% resin binder. 2.2 Overcoating of CP During molding of fuel elements, coated fuel particles may interact due to high pressure and crack. In the manufacture of HTR-10 fuel elements, coated fuel particles are overcoated with graphite matrix powder in a rotation drum prior to pressing in order to avoid breakage of particles during pressing due to direct contact between them. The overcoating layer is about 200 μm in thickness. A single overcoating batch consists of about 5 kg, which can produce about 500 spherical fuel elements. The quality of overcoating depends on the angle and the rotation velocity of the overcoating drum, the rate of addition of matrix powder, and the insufflation rate of alcohol. 2.3 Molding The irradiation resistance of graphite matrix depends on the anisotropy, grain size and degree of graphitization. The anisotropy of graphite matrix of spherical elements produced through traditional molding was great, and the irradiation resistance was poor. To decrease anisotropy, isostatic molding or quasi-isostatic molding should be employed. For the HTR-10, spherical fuel elements were manufactured by cold quasi-isostatic molding for which the manufacture of spherical and multilayer configuration and the final size is precise, and the technology is very concise. Cold quasi-isostatic molding with a silicon rubber die comprises two steps: the pre-molding of the fuel zone of the sphere at a low pressure of about 3 MPa and the final molding of the sphere at a pressure of about 300 MPa. 2.4 Heat treatment Heat treatment consists of two steps: carbonization up to 800 °C under argon atmosphere, and purification at 1950 °C under vacuum. The pyrolytic gases released during the carbonization process were collected and the thermal gravimetric analysis and pyrolytic-chromatograph-mass spectrum analysis of the phenolic resin were examined. Fig. 2 shows the curve of thermal gravimetric analysis of the phenolic resin up to 800 °C. It indicates that there was only a little volatilization below 200 °C. The release of pyrolytic gases gradually increased above 200 °C, and a great deal of pyrolytic gases was released in the range of 340–600 °C, while the volume of the released gases gradually decreased above 600 °C. Fig. 2 also shows that there are two pyrogenation peaks of weight loss at 385.6 and 560.6 °C, respectively. The pyrolytic-chromatograph spectra of the resin at 385 and 560 °C are shown in Fig. 3 . The results show that the volatile component at 385 °C consisted mainly of vapour, CO and CO 2 . While at 560 °C, besides vapour, CO and CO 2 , the volatile component consists mainly of C 4 H 5 , C 6 H 5 OH. According to the above results, the time–temperature curve was confirmed in the manufacture of spherical fuel elements for HTR-10, and the total carbonization time is 30 h. Some impurities exist in the raw graphite and resin, and some impurities can be introduced during the manufacturing process of graphite matrix materials. Therefore, the purifying process at high temperature is necessary, which can improve corrosion resistance of graphite matrix materials. In the manufacture of HTR-10 fuel elements, the purifying process was carried out under vacuum at 1950 °C for 1 h. 3 Quality control of HTR-10 spherical fuel elements Development and qualification of fuel elements for HTR-10 have been determined, at all stages, by the general performance requirements as follows: (1) Optimal fission product retention capability. The fractional release of radiologically relevant nuclides from fuel elements well below 10 −4 under normal and design-basis accident conditions. (2) High mechanical strength of the integral fuel element. (3) High corrosion resistance with respect to oxidizing agents in the primary coolant. (4) Sufficient dimensional stability. (5) Efficient heat transfer characteristics. Forty-four batches of fuel elements using qualified TRISO particles, consisting of about 20,540 fuel elements have been produced for the first loading of HTR-10. Sampling methods had to be established to ensure that samples were representative of the product. Sampling includes taking suitable sample size and representative sample. In China, acceptance standards of inspection items are calculated statistically based on the design specification. Table 2 summarizes the inspection items, methods and sample rate for HTR-10 fuel elements. The diameter, shell thickness and appearance have to be examined on a 100% basis. Nine spherical fuel elements are sampled from each batch to inspect the uranium loading, uranium contamination and free uranium fraction, respectively. The other property inspections for HTR-10 fuel element are carried out by measuring 55 reference graphite balls, which are produced in the same batch and used the fabrication process as the corresponding batch of the fuel element. The design specifications and the mean value of 44 batches of the HTR-10 spherical fuel elements are also listed in Table 2 . It indicates that the graphite matrix materials met the design specifications and the mean free uranium fraction was 4.57 × 10 −5 . 4 Irradiation performance of HTR-10 spherical fuel elements In-pile irradiation behavior test of matrix graphite and spherical fuel elements started in July 2000 in the Russian IVV-2M research reactor, and ended in February 2003 ( Tang et al., 2004a,b ). The irradiation temperature was 1000 ± 50 °C. The fast neutron fluence was 1.30 × 10 21 n/cm 2 . There were five capsules in the irradiation test. There were 60 matrix graphite samples with the size of 5 mm × 5 mm × 40 mm in Capsule 1 and four spherical fuel elements sampled randomly from the first and second batches of HTR-10 production in four capsules (from Capsule 2 to Capsule 5). The changes in linear dimension, geometrical density, porosity, strength of matrix graphite samples and spherical fuel elements before and after irradiation were observed and measured. The main results of irradiation test are listed in Tables 3 and 4 . It is shown from Table 3 that the average shrinkage of the length of matrix graphite samples was about 0.3%, while the average shrinkage of the diameter of spherical fuel elements was about 0.6%. The reason for the difference in both directions was not found out. Irradiation did not cause any weight change of matrix graphite samples. The in-pile irradiation led to the increase of the density and open pores of matrix graphite samples, and decrease of closed pores. The relative change of the density was about 0.9%. The irradiation also led to the increase of the bending strength of matrix graphite samples. The increase of average bending strength of matrix graphite samples perpendicular and parallel to the pressing direction was about 6.5% and about 16.2%, respectively. The results of dimensional change of spherical fuel element caused by irradiation test are listed in Table 4 and the primary results are satisfied. It is shown from the visual inspection results that the appearances of Capsule 2, Capsule 3 and Capsule 5 have not changed and no cracks and blisters were observed. However, Capsule 4 lost its integrity for unknown reason. There was no gas gap between the spherical fuel element and the graphite cap. It was filled up with graphite powder. The reason for the damage was not clear. 5 Conclusions The development of manufacture and qualification of the spherical fuel elements for HTR-10 have been performed. The fabrication technology and the matrix graphite materials were investigated and optimized. Fuel elements for the first loading of HTR-10 have been produced. The cold properties of the spherical fuel elements meet the design specifications. The mean free uranium fraction of 44 batches was 4.57 × 10 −5 . In pile irradiation test results show that the irradiation did not lead to apparent change in linear dimensional, geometrical density, porosity, strength of the matrix graphite samples and no cracks and blisters were observed in spherical fuel elements. It indicated that the matrix graphite and spherical fuel elements produced for HTR-10 met the requirement of design specifications. References Chernikov et al., 1991 A.S. Chernikov L.I. Mikgailichenko A.A. Kuzentsov V.A. Reshetnikov A.S. Cherkasov State of HTGR fuel element development Second Soviet-German Seminar on HTR Fuel and Graphite Jülich, Germany 1991 Delle et al., 1985 W. Delle R.-E. Schulze L. Binkele G. Haag W. Rind H.A. Schulze Warm-moulded graphitic matrix for spherical HTR fuel elements Jül-Conf-52 Germany 1985 Mehner et al., 1990 A.W. Mehner W. Heit K. Röllig H. Ragoß H. Müller Spherical fuel elements for advanced HTR manufacture and qualification by irradiation testing J. Nucl. Mater. 171 1990 9 18 Schulze et al., 1981 Schulze, R.E., Schulze, H.A., Rind, W., 1981. Graphitische Matrixwerkstoffe fuer kugelfoermige HTR-Brennelemente Juel-1752. Tang et al., 2002 C.H. Tang Y.P. Tang J.G. Zhu Y.W. Zou J.H. Li X.J. Ni Design and manufacture of the fuel element for the 10 MW high temperature gas-cooled reactor Nucl. Eng. Des. 218 2002 91 102 Tang et al., 2004a C.H. Tang X.M. Fu J.G. Zhu K.N. Koshceev A.V. Kozlov O.G. Karlov Yu.G. Degaltsev V.I. Vasiliev The behavior of HTR-10 fuel under irradiation Second International Topical Meeting on High Temperature Reactor Technology Beijing, China 2004 Tang et al., 2004b C.H. Tang X.M. Fu J.G. Zhu K.N. Koshceev A.V. Kozlov O.G. Karlov Yu.G. Degaltsev V.I. Vasiliev Irradiation performance of matrix graphite of HTR-10 fuel elements The Fifth international Nuclear Graphite Specialists’ Meeting Plas Tan-Y-Bwlch, Maentwrog, Gwynedd, Wales, UK 2004 Zelenskij et al., 1991 V.F. Zelenskij V.A. Gurin Yu.F. Konotop Yu.A. Deryuga V.A. Kolosenko IAEA-TECDOC-696, the status of graphite development for gas cooled reactors Proceedings of a Specialists Meeting Tokai-mural, Japan 1991",
        "keywords": [],
        "authors": [
            {
                "name": "Hongsheng Zhao",
                "org": ""
            },
            {
                "name": "Tongxiang Liang",
                "org": "Institute of Nuclear and New Energy Technology, Tsinghua University, Beijing 100084, China"
            },
            {
                "name": "Jie Zhang",
                "org": "Institute of Nuclear and New Energy Technology, Tsinghua University, Beijing 100084, China"
            },
            {
                "name": "Jun He",
                "org": "Institute of Nuclear and New Energy Technology, Tsinghua University, Beijing 100084, China"
            },
            {
                "name": "Yanwen Zou",
                "org": "Institute of Nuclear and New Energy Technology, Tsinghua University, Beijing 100084, China"
            },
            {
                "name": "Chunhe Tang",
                "org": "Institute of Nuclear and New Energy Technology, Tsinghua University, Beijing 100084, China"
            }
        ],
        "venue": "Nuclear Engineering and Design",
        "year": 2006
    },
    "8WXLEKxi": {
        "id": "8WXLEKxi",
        "title": "Study of the composite bipolar plates for PEMFC",
        "abstract": "Resin/graphite composite PEMFC bipolar plates using thermoplastic-resin as the binder were newly prepared by pressing.The influences of the temperature,pressures,resin and conductive fillers(graphite)on the properties of the bipolar plates were researched.The results show that the solvent dissolving is better than the direct mixing in relatively low temperature and pressures.For the preferable preparation,the resin content,the proportion of natural and manmade graphite,temperature and pressures should be 10%～16 %,about 1∶1,130-160 ℃ and 8-12 MPa.",
        "keywords": [
            "fuel cell",
            "composite materials",
            "thermoplastic-resin",
            "bipolar plate"
        ],
        "authors": [
            {
                "name": "SUN Bin",
                "org": "Institute of Nuclear and New Energy Technology,Tsinghua University,Beijing ,China"
            },
            {
                "name": "ZOU Yan-wen",
                "org": "Institute of Nuclear and New Energy Technology,Tsinghua University,Beijing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Institute of Nuclear and New Energy Technology,Tsinghua University,Beijing ,China"
            },
            {
                "name": "HE Jun",
                "org": "Institute of Nuclear and New Energy Technology,Tsinghua University,Beijing ,China"
            },
            {
                "name": "ZHENG Yong-ping",
                "org": "Institute of Nuclear and New Energy Technology,Tsinghua University,Beijing ,China"
            }
        ],
        "venue": "Chinese Journal of Power Sources",
        "year": 2006
    },
    "1O1PSQjH": {
        "id": "1O1PSQjH",
        "title": "Study on the Preparation of CeO_2/γ-Al_2O_3 Desulfurizer and Sulfation Kinetics",
        "abstract": "In this paper 0.03gCeO_2/g(γ-Al_2O_3)adsorbent was prepared by impregnation and characterized by X- ray diffraction which showed that the dispersion of CuO supported onγ-Al_2O_3 was submonolayer.Thermogravimetric technique was used to study the intrinsic sulfation kinetics of CeO_2/g-Al_2O_3 sorbent.With increasing SO2 concen- tration and temperature,conversion would increase.Intrinsic kinetics equation was R=1.1394E(-4)oexp(- 1508.39/T)mg/mg·s.Activation of CeO_2 supported onγ-Al_2O_3 lowered much compared with that of pure CeO_2. Activation energy,reaction order with respect to SO_2,and pre-exponential were 12540.78J/mol,first order,and 1.1394Exp (-4) mg(mgos)-1 respectively.0.03gCeO_2/g(γ-Al_2O_3) desulfurizer could be regenerated,but long time would reduce its regeneration performance.",
        "keywords": [
            "CeO_2/γ-Al_2O_3",
            "desulfurizer",
            "kinetics"
        ],
        "authors": [
            {
                "name": "YU Qing-chun",
                "org": " Institute of Nnclear and Energy Technology,Tsinghua University,Beijing ,China"
            },
            {
                "name": "ZHANG Shi-chao",
                "org": " Institute of Nnclear and Energy Technology,Tsinghua University,Beijing ,China"
            },
            {
                "name": "WANG Xin-dong",
                "org": " Institute of Nnclear and Energy Technology,Tsinghua University,Beijing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": " Institute of Nnclear and Energy Technology,Tsinghua University,Beijing ,China"
            },
            {
                "name": "LU Zhen-ming",
                "org": " Institute of Nnclear and Energy Technology,Tsinghua University,Beijing ,China"
            }
        ],
        "venue": "Clean Coal Technology",
        "year": 2007
    },
    "6gTdPyR3": {
        "id": "6gTdPyR3",
        "title": "Study on Sulfation of CeO_2/γ-Al_2O_3 Sorbent in Simulated Flue Gas",
        "abstract": "The sulfation of CeO2/γ-Al2O3 sorbent in simulated flue gas was studied. A series of CeO2/γ-Al2O3 sorbents with different CeO2 loadings were prepared by impregnation and characterized by X-ray diffraction. Thermogravimetric technique was used to study the sulfation of CeO2/γ-Al2O3 sorbents, mainly on the CeO2 loading, sulfation cycles, and intrinsic kinetics. The study revealed that monolayer coverage of CeO2 supported on γ-Al2O3 was 0.125 g CeO2/g (γ-Al2O3). Below monolayer coverage, CeO2 was highly dispersed on γ-Al2O3. The optimal CeO2 loading on sulfation was 0.03 g CeO2/g (γ-Al2O3). CeO2/γ-Al2O3 sorbent was recyclable by controlling sulfation time. Intrinsic kineticd equation was R=1.1394×10-4×exp (-1,508.39/T) mg·mg-1·s-1. Activation energy and reaction order were 12.54 kJ·mol-1 and first order, respectively.",
        "keywords": [
            "CeO2/γ-Al2O3",
            "intrinsic kinetics",
            "SO2",
            "rare earths",
            "recyclable"
        ],
        "authors": [
            {
                "name": "Yu Qingchun",
                "org": " Department of Physical Chemistry, University of Science and Technology Beijing, Beijing , China"
            },
            {
                "name": "Zhang Shichao",
                "org": " School of Material Science and Engineering, Beijing University of Aeronautics and Astronautics, Beijing , China"
            },
            {
                "name": "Wang Xindong",
                "org": " Department of Physical Chemistry, University of Science and Technology Beijing, Beijing , China"
            },
            {
                "name": "Zhang Jie",
                "org": " Institute of Nuclear and Energy Technology, Tsinghua University, Beijing , China"
            },
            {
                "name": "Lu Zhenming",
                "org": " Institute of Nuclear and Energy Technology, Tsinghua University, Beijing , China"
            }
        ],
        "venue": "稀土学报(英文版)",
        "year": 2007
    },
    "WnMVEXBN": {
        "id": "WnMVEXBN",
        "title": "Preparing amorphous graphite/resin bipolar plate by mould pressing process",
        "abstract": "Amorphous graphite/resin composite bipolar plates for PEMFC were prepared by mould pressing process.Thermosetting resin was used as the binder and amorphous graphite as the conductive filler.The effects of filler particle size,filler content,thermosetting resin and moulding condition on the performance of bipolar plates were studied.The bipolar plate prepared with thermosetting resin P104-02 whose content was 18%～20% as binder,amorphous graphite whose particle size was 200～250 mesh as conductive filler,in the moulding condition of 140～145 ℃,15～20 MPa and 18～22 min had such performance:flexural strength >25 MPa,conductivity >100 S/cm,permeability <3×10-5 ml/(s·cm2).",
        "keywords": [
            "proton exchange membrane fuel cell(PEMFC)",
            "thermosetting resin",
            "bipolar plate",
            "composite"
        ],
        "authors": [
            {
                "name": "LIN Zheng-yu",
                "org": "Institute of Nuclear and New Energy Technology,Tsinghua University,Beijing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Institute of Nuclear and New Energy Technology,Tsinghua University,Beijing ,China"
            },
            {
                "name": "LIU Bing",
                "org": "Institute of Nuclear and New Energy Technology,Tsinghua University,Beijing ,China"
            }
        ],
        "venue": "Battery Bimonthly",
        "year": 2011
    },
    "FoZk9mT2": {
        "id": "FoZk9mT2",
        "title": "Proton Exchange Membrane Fuel Cell Materials",
        "abstract": "Proton exchange membrane fuel cell(PEMFC),which is the closest to commercialization in all the five types of fuel cells,is one of the most promising power sources as the future electric vehicle engine and has rapid progress in the past two decades.To date,the biggest obstacles in the way of PEMFC’s commercialization are cost and lifetime,which must be solved by searching and developing novel materials.These areas have already become the keystones and hotspots in PEMFC ’s research and development.In this paper,recent years ’ developments on the key materials of PEMFC are reviewed.Firstly,the development in proton exchange membrane is introduced including the directions of fluorinated membrane,non-fluorinated membrane,high temperature membrane,inorganic ceramic membrane and so on.Secondly,the recent progress in platinum based and non-platinum electrocatalyst used in PEMFC is introduced;thirdly,the research results of the characteristics and materials of the gas diffusion layer in PEMFC is introduced.In the last,bipolar plates materials and their machining methods of graphite,metal and composite materials for PEMFC are reviewed.The authors also comment the state-of-the-art development of each material,and provide outlook of the future develop directions of the PEMFC materials.",
        "keywords": [
            "fuel cell",
            "proton exchange membrane",
            "material"
        ],
        "authors": [
            {
                "name": "Liu Zhixiang",
                "org": "Institute of Nuclear and New Energy Technology,Tsinghua University,Beijing ,China"
            },
            {
                "name": "Qian Wei",
                "org": "Institute of Nuclear and New Energy Technology,Tsinghua University,Beijing ,China"
            },
            {
                "name": "Guo Jianwei",
                "org": "Institute of Nuclear and New Energy Technology,Tsinghua University,Beijing ,China"
            },
            {
                "name": "Zhang Jie",
                "org": "Institute of Nuclear and New Energy Technology,Tsinghua University,Beijing ,China"
            },
            {
                "name": "Wang Cheng",
                "org": "Institute of Nuclear and New Energy Technology,Tsinghua University,Beijing ,China"
            },
            {
                "name": "Mao Zongqiang",
                "org": "Institute of Nuclear and New Energy Technology,Tsinghua University,Beijing ,China"
            }
        ],
        "venue": "Progress in Chemistry",
        "year": 2011
    },
    "cqfiVhbB": {
        "id": "cqfiVhbB",
        "title": "Graphite materials in pebble-bed high temperature gas-cooled reactors",
        "abstract": "As the core structural material and fuel element matrix in high temperature gas-cooled reactors(HTGR),graphite withstands extreme conditions such as high temperature and high doses of irradiation.In this paper the functions,environments and technical requirements of structural graphite used in pebble-bed HTGR were presented.Also the characteristics such as the physical,technologic and chemical characteristics of matrix graphite particles used in pebble fuel elements were discussed in detail.",
        "keywords": [
            "natural graphite",
            "pebble fuel elements",
            "structural graphite",
            "artificial graphite",
            "HTGR"
        ],
        "authors": [
            {
                "name": "ZHOU Xiang-wen",
                "org": "Institute of Nuclear and New Energy Technology,Tsinghua University,Beijing ,China"
            },
            {
                "name": "YI Zi-long",
                "org": "Institute of Nuclear and New Energy Technology,Tsinghua University,Beijing ,China"
            },
            {
                "name": "LU Zhen-ming",
                "org": "Institute of Nuclear and New Energy Technology,Tsinghua University,Beijing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Institute of Nuclear and New Energy Technology,Tsinghua University,Beijing ,China"
            },
            {
                "name": "YU Su-yuan",
                "org": "Institute of Nuclear and New Energy Technology,Tsinghua University,Beijing ,China"
            }
        ],
        "venue": "Carbon Techniques",
        "year": 2012
    },
    "yovus04E": {
        "id": "yovus04E",
        "title": "Overcoating process and equipments development in manufacture of fuel elements for HTR-PM",
        "abstract": "The equipments used in the overcoating process was developed, which comprise overcoating system, rotating screen, sorting device, homogenize equipment, and recovery system for unqualified overcoated particles. The results of batch experiments using optimized parameters show that the yield is high and stable. The failure ratio of coated particles in fuel elements satisfies design parameter. The equipments are easy to operation and control, and can satisfy the large-scale production of overcoated particles of fuel elements for HTR-PM.",
        "keywords": [
            "HTR-PM",
            "Overcoating system",
            "Spherical fuel element"
        ],
        "authors": [
            {
                "name": "LU Zhen-ming",
                "org": "Tsinghua University(Tsinghua University,Tsinghua Univ,Tsinghua Univ.),Beijing,China"
            },
            {
                "name": "ZHOU Xiang-wen",
                "org": "Tsinghua University(Tsinghua University,Tsinghua Univ,Tsinghua Univ.),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Tsinghua University(Tsinghua University,Tsinghua Univ,Tsinghua Univ.),Beijing,China"
            },
            {
                "name": "Bing Liu",
                "org": "Tsinghua University(Tsinghua University,Tsinghua Univ,Tsinghua Univ.),Beijing,China"
            }
        ],
        "venue": "Yuanzineng Kexue Jishu/Atomic Energy Science and Technology",
        "year": 2012
    },
    "AlZxIVDP": {
        "id": "AlZxIVDP",
        "title": "Key Process of Overcoating for Coated Particles in Manufacture of Fuel Elements for HTGR",
        "abstract": "With the commercial development of high temperature gas-cooled reactor(HTGR),higher requirements for large-scale production of overcoated particles of fuel elements were put forward.The impacts of rotating speed of drum on dynamic surface angle,repose angle and particle size distribution were studied.The key process parameters were optimized and determined,and the causes of unqualified particles were also analyzed.The results of batch experiments using optimized parameters show that the yield is high and stable and the average yield reaches 93.94%.The overcoating equipment is easy to operate and control,and can satisfy the scale production.",
        "keywords": [
            "Coated particle",
            "High temperature gas-cooled reactor",
            "Overcoat",
            "Spherical fuel element"
        ],
        "authors": [
            {
                "name": "LU Zhen-ming",
                "org": "Institute of Nuclear and New Energy Technology,Tsinghua University,Beijing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Institute of Nuclear and New Energy Technology,Tsinghua University,Beijing ,China"
            },
            {
                "name": "WANG Yi-min",
                "org": "Institute of Nuclear and New Energy Technology,Tsinghua University,Beijing ,China"
            },
            {
                "name": "TANG Ya-ping",
                "org": "Institute of Nuclear and New Energy Technology,Tsinghua University,Beijing ,China"
            },
            {
                "name": "Yanwen Zou",
                "org": "Tsinghua University(Tsinghua University,Tsinghua Univ,Tsinghua Univ.),Beijing,China"
            }
        ],
        "venue": "Atomic Energy Science and Technology",
        "year": 2012
    },
    "M3tQT7b4": {
        "id": "M3tQT7b4",
        "title": "Factors Influencing Flyings' Generation in Cellulose Acetate Tow Production and Measures for Reducing the Same",
        "abstract": "X-ray diffraction,thermogravimetric analysis and tow tensile test were adopted to analyze the factors influencing flyings' generation,such as wood pulp,tow tension,running status of crimper,tow oiling,spinning solution filtration and TiO2.The results showed that it was the characteristics of wood pulp and variations of physical and chemical properties between different batches that made flyings' generation unavoidable,however,flyings could be effectively reduced by decreasing tow tension and tow overfeed,and properly setting the pressure between paired rollers and pressure of compressor plate in crimper.",
        "keywords": [
            "Wood pulp",
            "Cellulose acetate tow",
            "Flyings",
            "Spinning"
        ],
        "authors": [
            {
                "name": "HUANG JIAN-XIN",
                "org": "Nantong Cellulose Fibers Co.,Ltd.,Nantong ,Jiangsu,China"
            },
            {
                "name": "MA XIAO-LONG",
                "org": "Nantong Cellulose Fibers Co.,Ltd.,Nantong ,Jiangsu,China"
            },
            {
                "name": "YANG ZHAN-PING",
                "org": "Nantong Cellulose Fibers Co.,Ltd.,Nantong ,Jiangsu,China"
            },
            {
                "name": "ZHANG JIE",
                "org": "Nantong Cellulose Fibers Co.,Ltd.,Nantong ,Jiangsu,China"
            },
            {
                "name": "CAO JIANHUA",
                "org": "Nantong Cellulose Fibers Co.,Ltd.,Nantong ,Jiangsu,China"
            }
        ],
        "venue": "Tobacco Science & Technology",
        "year": 2008
    },
    "wEVCiD9j": {
        "id": "wEVCiD9j",
        "title": "Change of Filtration Efficiency of Filter During Cigarette Smoking",
        "abstract": "The mainstream smoke constituents retained by Cambridge filter pad and cigarette filter were analyzed puff by puff under the standard smoking regime, and the change of total particulate matter filtration efficiency (TPMFE), nicotine filtration efficiency (NFE) and tar filtration efficiency (TFE) was studied. The results showed that: 1) the filtration efficiency differed from puff to puff; 2) TPMFE and TFE increased, while NFE decreased puff after puff, their order was TPMFE>TFE>NFE at the end of smoking; 3) when the filter length increased from 20 mm to 30 mm, the order of TPMFE and TFE changed from TFE>TPMFE to TPMFE>TFE during first puffing, while the change trends of TPMFE, TFE and NFE did not affected by filter length during the whole process of smoking.",
        "keywords": [
            "Filter",
            "Puff by puff",
            "Filtration efficiency"
        ],
        "authors": [
            {
                "name": "YU TAO",
                "org": " Technology Center of Nantong Cellulose Fibers Co., Ltd., Nantong , Jiangsu, China"
            },
            {
                "name": "ZHANG JIE",
                "org": " Technology Center of Nantong Cellulose Fibers Co., Ltd., Nantong , Jiangsu, China"
            },
            {
                "name": "CAO JIAN-HUA",
                "org": " Technology Center of Nantong Cellulose Fibers Co., Ltd., Nantong , Jiangsu, China"
            },
            {
                "name": "CHEN YUN",
                "org": " Technology Center of Nantong Cellulose Fibers Co., Ltd., Nantong , Jiangsu, China"
            },
            {
                "name": "GUO YE-SHU",
                "org": " Technology Center of Nantong Cellulose Fibers Co., Ltd., Nantong , Jiangsu, China"
            }
        ],
        "venue": "Tobacco Science & Technology",
        "year": 2009
    },
    "dsM4CPFD": {
        "id": "dsM4CPFD",
        "title": "Advances in the application of activated carbon fiber in cigarette filter",
        "abstract": "As a highly effective absorption materials,activated carbon fiber is superior to granular activated carbon(GAC) in many aspects.However,GAC has much wider applications.The application and progress of activated carbon fibers in cigarette filter in the last twenty yearsr were reviewed and its prospect was discussed.",
        "keywords": [
            "harm reduction",
            "absorption",
            "filter",
            "activated carbon fiber"
        ],
        "authors": [
            {
                "name": "YU Tao",
                "org": " Technology Center of Nantong Cellulose Fibers Co.,Ltd.,Nantong ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": " Technology Center of Nantong Cellulose Fibers Co.,Ltd.,Nantong ,China"
            },
            {
                "name": "CAO Jian-hua",
                "org": " Technology Center of Nantong Cellulose Fibers Co.,Ltd.,Nantong ,China"
            },
            {
                "name": "CHEN Yun",
                "org": " Technology Center of Nantong Cellulose Fibers Co.,Ltd.,Nantong ,China"
            },
            {
                "name": "DOU Feng",
                "org": " Technology Center of Nantong Cellulose Fibers Co.,Ltd.,Nantong ,China"
            }
        ],
        "venue": "Acta Tabacaria Sinica",
        "year": 2009
    },
    "GQ6IA5Yn": {
        "id": "GQ6IA5Yn",
        "title": "Preparation of Glutathione Emulsion and Its Application in Modified Cellulose Acetate Tow",
        "abstract": "Emulsion containing 1.52% mass fraction glutathione was prepared.Glutathione was coated on the surface of fibers via oil process,and the chemical properties of the cellulose acetate tow were modified.We analyzed the physical properties and surface morphology of the modified cellulose acetate tow.The contents of the common components and free radicals in cigarette smoke were also analyzed.The results showed that the manufacturing properties of the modified cellulose acetate tow were similar to that of common tow.The tar content in main smoke was reduced by 1.08 mg.The particulate-phase and gas-phase free radicals in the smoke can be reduced by up to 21.34% and 25.07%.",
        "keywords": [
            "free radical",
            "cellulose acetate tow",
            "glutathione",
            "emulsion"
        ],
        "authors": [
            {
                "name": "MA Xiao-Long",
                "org": "Nantong Cellulose Fibers Co.Ltd,Nantong "
            },
            {
                "name": "CHEN Yun",
                "org": "Nantong Cellulose Fibers Co.Ltd,Nantong "
            },
            {
                "name": "CAO Jian-Hua",
                "org": "Nantong Cellulose Fibers Co.Ltd,Nantong "
            },
            {
                "name": "ZHANG JIE",
                "org": "Nantong Cellulose Fibers Co.Ltd,Nantong "
            },
            {
                "name": "LU Xin",
                "org": "Key Laboratory of Industrial Biotechnology,Jiangnan University,Wuxi"
            },
            {
                "name": "HUA Zhao-Zhe",
                "org": "Key Laboratory of Industrial Biotechnology,Jiangnan University,Wuxi"
            },
            {
                "name": "CHEN Jian",
                "org": "Key Laboratory of Industrial Biotechnology,Jiangnan University,Wuxi"
            }
        ],
        "venue": "Chinese Journal of Applied Chemistry",
        "year": 2009
    },
    "81NUMe1W": {
        "id": "81NUMe1W",
        "title": "Study on selective filtration of major phenolic compounds in mainstream cigarette smoke by cellulose acetate filter",
        "abstract": "The filtration characteristics of cellulose acetate filter were studied by measuring filtration efficiency of seven phenolic compounds in mainstream smoke of different cigarettes. Results showed that phenolic compounds were selectively filtered by cellulose acetate fiber with priority order of phenol,o-cresol,m-cresol and p-cresol,catechol,resorcinol and hydroquinone.The selectivity for monohydric phenols by cellulose acetate filter was higher than that for bispheols. The selective filtration order was also proved by a selectivity index,Sx,defined as (1-ENFDPM)/(1-Ex).",
        "keywords": [
            "mainstream smoke",
            "phenolic compounds",
            "selective filtration",
            "cellulose acetate filter"
        ],
        "authors": [
            {
                "name": "YU Tao",
                "org": " Technical Center,Nantong Cellulose Fibers Co.Ltd,No.27,Zhongxiu East Road,Nantong,,China"
            },
            {
                "name": "ZHANG Jie",
                "org": " Technical Center,Nantong Cellulose Fibers Co.Ltd,No.27,Zhongxiu East Road,Nantong,,China"
            },
            {
                "name": "CAO Jian-hua",
                "org": " Technical Center,Nantong Cellulose Fibers Co.Ltd,No.27,Zhongxiu East Road,Nantong,,China"
            },
            {
                "name": "GU Hai-bing",
                "org": " Technical Center,Nantong Cellulose Fibers Co.Ltd,No.27,Zhongxiu East Road,Nantong,,China"
            },
            {
                "name": "CUI Lei",
                "org": " Technical Center,Nantong Cellulose Fibers Co.Ltd,No.27,Zhongxiu East Road,Nantong,,China"
            }
        ],
        "venue": "Acta Tabacaria Sinica",
        "year": 2009
    },
    "QpMgVXoy": {
        "id": "QpMgVXoy",
        "title": "Study on Producing of Functional Cellulose Acetate Tow by Porous Starch with Immobilized Catalase",
        "abstract": "The porous starch with immobilized catalase was prepared and dispersed in the spinning dope to be spinned into functional cellulose acetate tow. The physical properties,surface morphology of the functional cellulose acetate tow and the routine analytes and free radicals in mainstream smoke of cigarette tipped with the filter make of the tow were analyzed. The results showed that: the running property of the functional cellulose acetate tow was similar to that of normal tow. The tar delivery of mainstream cigarette smoke reduced by 10%,and the deliveries of nicotine and CO were almost unchanged. The contents of particulate phase and gas phase free radicals in smoke decreased by 38.36% and 28.57%,respectively.",
        "keywords": [
            "Free radical",
            "Porous starch",
            "Catalase",
            "Functional cellulose acetate tow"
        ],
        "authors": [
            {
                "name": "MA XIAO-LONG",
                "org": "School of Science,Nanjing University of Technology,Nanjing ,China;Technical Center of Nantong Cellulose Fibers Co.,Ltd.,Nantong ,China"
            },
            {
                "name": "SONG MIN-FENG",
                "org": "Technical Center of Nantong Cellulose Fibers Co.,Ltd.,Nantong ,China"
            },
            {
                "name": "ZHANG JIE",
                "org": "Technical Center of Nantong Cellulose Fibers Co.,Ltd.,Nantong ,China"
            },
            {
                "name": "CAO JIAN-HUA",
                "org": "Technical Center of Nantong Cellulose Fibers Co.,Ltd.,Nantong ,China"
            }
        ],
        "venue": "Tobacco Science & Technology",
        "year": 2009
    },
    "CyPZwMUQ": {
        "id": "CyPZwMUQ",
        "title": "Study on the Acetylation Reaction of Cotton Linters by Reaction Calorimeter",
        "abstract": "The acetylation reaction of cotton linters was studied by reaction calorimeter(RCle).It was found that the reaction exothermic rate map consisted of three to four exothermic peaks.The first or second peak value was larger due mainly to the hydrolysis of acetic anhydride,and the subsequent prak values became gradually smaller due to the acetylation of cotton linters.The effects of reaction temperature and moisture content on the exothermic rates were also studied.Experimental results showed that the acetylation of cotton linters reflected the characteristics of heterogeneous surface reaction.The exothermic rates increased with the increase of reaction temperature.Increasing moisture content in the cotton linters led to higher reaction rate and shorter total reaction time.Compared with wood pulp,cotton linters have lower moisture content,higher crystallinity and higher cellulose content.Its reaction exothermic characters showed the lower heat release rate in the initial stage than wood pulp,higher in the middle and later,and the longer total reaction time.",
        "keywords": [
            "acetylation",
            "heterogeneous surface reaction",
            "cotton linters",
            "reaction calorimetry"
        ],
        "authors": [
            {
                "name": "LIANG Yin-chun",
                "org": "Nantong Cellulose Fibers Co.,Ltd.,Nantong ,China"
            },
            {
                "name": "MA Xiao-long",
                "org": "Nantong Cellulose Fibers Co.,Ltd.,Nantong ,China"
            },
            {
                "name": "CHEN Yun",
                "org": "Nantong Cellulose Fibers Co.,Ltd.,Nantong ,China"
            },
            {
                "name": "HUANG Yu-qing",
                "org": "Nantong Cellulose Fibers Co.,Ltd.,Nantong ,China"
            },
            {
                "name": "CAO Jian-hua",
                "org": "Nantong Cellulose Fibers Co.,Ltd.,Nantong ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Nantong Cellulose Fibers Co.,Ltd.,Nantong ,China"
            }
        ],
        "venue": "Journal of Cellulose Science and Technology",
        "year": 2010
    },
    "vbDmLuh2": {
        "id": "vbDmLuh2",
        "title": "Characterization of Properties of Domestic Cotton Linters Pulp and Its Acetylation Behavior",
        "abstract": "In order to develop the domestic raw material of cellulose acetate,scanning electronic microscopy,X-ray diffraction,thermal gravity analysis,infrared spectrum and hemi-cellulose analysis were used to characterize the physical and chemical properties of domestic acetate-grade cotton linters pulp.The acetylating reactivity was also studied.The results show that domestic acetate-grade cotton linters pulp has high α-cellulose content,high crystallinity and low hemi-cellulose content.The acetylation reactivity of cotton linters pulp was worse than wood pulp.The whiteness and haze of flake made from cotton linters pulp is better than wood pulp.",
        "keywords": [
            "cotton linters pulp",
            "acetylation",
            "domestic raw material",
            "cellulose acetate flake",
            "acetate-grade pulp"
        ],
        "authors": [
            {
                "name": "MA Xiao-long",
                "org": "1.Technical Center of Nantong Cellulose Fibers Co.Ltd.,Nantong ,China ;2.School of Science,Nanjing University of Technology,Nanjing ,China"
            },
            {
                "name": "LE Bao-xiang",
                "org": "1.Technical Center of Nantong Cellulose Fibers Co.Ltd.,Nantong ,China "
            },
            {
                "name": "SHEN Lin",
                "org": "1.Technical Center of Nantong Cellulose Fibers Co.Ltd.,Nantong ,China "
            },
            {
                "name": "PENG Wei-jun",
                "org": "1.Technical Center of Nantong Cellulose Fibers Co.Ltd.,Nantong ,China "
            },
            {
                "name": "ZHANG Jie",
                "org": "1.Technical Center of Nantong Cellulose Fibers Co.Ltd.,Nantong ,China "
            }
        ],
        "venue": "Journal of Cellulose Science and Technology",
        "year": 2010
    },
    "P7SF1VWV": {
        "id": "P7SF1VWV",
        "title": "Analysis of the factors influencing axillary brachial plexus block]",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Xue-hua Che",
                "org": "Department of Anesthesia, Affiliated Huashan Hospital, Fudan University, shanghai 200040, China"
            },
            {
                "name": "Wei-min Liang",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            }
        ],
        "venue": "Zhonghua yi xue za zhi",
        "year": 2005
    },
    "qURxmvKJ": {
        "id": "qURxmvKJ",
        "title": "The Exprassion and the Significance of NF-κB in the Sjgren's Syndrome",
        "abstract": "Objective: To observe the expression of nuclear transcription factor kappa B(NF-κB) in the specimens of labial gland of SjOgren's Syndrome(SS) and to investigate the role of regulation of NF-κB in SjOgren's Syndrome(SS). Methods: Im-munohistochemistry was used to examine the expression of NF-κB in the specimens of labial gland of 20 cases of SS and 8 cases of normal specimens . Results:(1)The positive expression level of NF-κB in the specimens of labial gland of 20 cases of SS had a notable predominance over that in the control group. The difference was significant (P<0.05). (2) The expression level of NF-κB was positively correlated with lymphocyte foci in SS labial gland samples. Conclusion: NF-κB plays an important role in regulating the activity of SS.",
        "keywords": [
            "Nuclear transcription factor kappa B",
            "Labial gland",
            "Immunohistochemistry",
            "SjOgrens syndrome"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "g,et al.Department of Stomatology,Huashan Hospital,Fudan University,Shanghai "
            },
            {
                "name": "SUN Hongying",
                "org": "g,et al.Department of Stomatology,Huashan Hospital,Fudan University,Shanghai "
            },
            {
                "name": "JIANG Yiwen",
                "org": "g,et al.Department of Stomatology,Huashan Hospital,Fudan University,Shanghai "
            }
        ],
        "venue": "Chinese Journal of Clinical Medicine",
        "year": 2006
    },
    "flG8Zwma": {
        "id": "flG8Zwma",
        "title": "Axillary brachial plexus block guided by peripheral nerve stimulator",
        "abstract": "Objective To evaluate the efficacy of axillary brachial plexus block guided by peripheral nerve stimulator(PNS)in surgeries of ulnar nerve neurolysis at the elbow,and compare two nerve-localization techniques with a PNS:double-injection versus triple-injection.Methods Sixty patients who were diagnosed with cubital tunnel syndrome and had indications for surgery were involved in the study.They were randomly divided into double-injections group(group 2N,n=30)and triple-injection group(group 3N,n=30).The museulocutaneous nerve and the radial nerve were located by PNS in group 2N while the musetdocutaneous, radial and median nerves were located in group 3N.Double injections and triple injections were done respectively.The brachial plexus block was defined as complete when analgesia was present in all the sensory area distal to the elbow.Success rate of blockade,latency time of analgesia and occurrence of complications were compared between two groups.Results The success rate of group 3N was higher than that of group 2N (95.5% vs 54.5%,P<0.01).This was related to a lower success rate for blocking the median nerves(P< 0.05).However the effect of anesthesia for surgery did not show significant difference between the two groups. Conclusion PNS guided axillary brachial plexus block leads to effective anesthesia for ulnar nerve release and anterior transposition at the elbow.Double-injections to block the musculocutaneous nerve and radial nerve is enough for this kind of operation.",
        "keywords": [
            "Nerve block",
            "Axilla",
            "Peripheral nerve stimulator",
            "Brachial plexus"
        ],
        "authors": [
            {
                "name": "ZHANG jie",
                "org": " HANG Wei-min Department of Anesthesiology,Huashan Hospital,Fudan University,Shanghai ,China"
            },
            {
                "name": "CHE Xue-hua",
                "org": " HANG Wei-min Department of Anesthesiology,Huashan Hospital,Fudan University,Shanghai ,China"
            }
        ],
        "venue": "Chinese Journal of Hand Surgery",
        "year": 2007
    },
    "uedTnd0N": {
        "id": "uedTnd0N",
        "title": "Effects of Butorphanol on Infraclavicular Brachial Plexus Block with Ropivacaine",
        "abstract": "Objective:To evaluate the clinical effects of butorphanol on infraclavicular brachial plexus block with ropivacaine.Methods:120 adult patients(ASAⅠ-Ⅱ) undergoing forearm or hand surgery were divided randomly into four groups.Every group was received 0.5%ropivacaine 30ml in infraclavicular brachial plexus block with PNS.Group B,group C and group D were also received butorphanol 0.5mg,1.0mg,2.0mg with ropivacaine in brachial plexus block except group A.The degree of nerve blockade was evaluated at 5,10,15,20,30 min after local anesthetic infusion.The onset time,the duration time of nerve blockade and intra-and postoperative VAS scores,side effects were recorded by another doctor.Results:The onset time of both four groups has no difference(P>0.05).The duration of nerve blockade in group C and D was obviously longer than that in group A and B(P<0.01).And the scores of VAS at postoperative 8h,12h,24h,36h in group A ang B was higher than that in group C and D(P<0.01).But the side effects in group D were more popular than anyother groups.Conclusion:The effect of butorphanol on infraclavicular brachial plexus block with ropivacaine is beneficial.It can prolong the time of postoperative analgesia obviously.Especially with the dosage in 1mg.",
        "keywords": [
            "Ropivacaine",
            "Infraclavicular brachial plexus block",
            "Butorphanol"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": " Department of Anesthesiology,Huashan Hospital,Fudan University,Shanghai "
            },
            {
                "name": "LI Peiying",
                "org": " Department of Anesthesiology,Huashan Hospital,Fudan University,Shanghai "
            },
            {
                "name": "LIANG Weimin",
                "org": " Department of Anesthesiology,Huashan Hospital,Fudan University,Shanghai "
            }
        ],
        "venue": "Chinese Journal of Clinical Medicine",
        "year": 2008
    },
    "M4nVSThg": {
        "id": "M4nVSThg",
        "title": "Imaging Evaluation of the Effect of Continuous Brachial Plexus Blockade",
        "abstract": "Purpose:We will discuss the efficacy of different length of catheter on upper limb surgery through the X-ray diagnosis.Meterials and Methods:Sixty adult patients scheduled for open rotator cuff repair were entered in this randomized,single-blinded study.Patients received an infraclavicular brachial plexus blockade and a continuous peripheral nerve catheter as their primary anesthetic,with the length of catheter of 1cm as Group A and 3cm as Group B,then assess the location of the catheter through the X-ray imaging after the contrast agent injected.6h,12h,18h,24h after infraclavicular block was measured.Results:X-ray showed two kinds of shape:strip and non-strip.when the length of catheter were 1cm in Group A,the rate of strip is higher,the success rate was 93.3%,while the length of catheter was 3cm in Group B,the rate of strip is lower,and the success rate was 70%.The success rate of Group A was higher than Group B(P<0.05).In another hand,VAS scores of Group A is lower than Group B postoperation.Conclusion:Continuous infraclavicular brachial plexus block can provide excellent postoperative analgesia according to the X-ray imaging.The length of catheter left in infraclavicular approach should be 1cm,which can improve the success rate.",
        "keywords": [
            "Infraclavicular approach",
            "Continuous brachial plexus block",
            "Postoperative analgesia",
            "X-ray imaging"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": " Department of Anesthesiology,Huashan Hospital,Fudan University"
            },
            {
                "name": "LIANG Wei-min",
                "org": " Department of Anesthesiology,Huashan Hospital,Fudan University"
            },
            {
                "name": "XU Ying-hua",
                "org": " Department of Anesthesiology,Huadong Hospital,Fudan University"
            }
        ],
        "venue": "Chinese Computed Medical Imaging",
        "year": 2008
    },
    "nNkUSDAm": {
        "id": "nNkUSDAm",
        "title": "Postoperative Analgesic Effects of Parecoxib Sodium Combined with Infraclavicular Brachial Plexus Block on Patients Undergoing Hand Surgery",
        "abstract": "Objective:To investigate the postoperative analgesic effects of parecoxib sodium combined with infraclavicular brachial plexus block on patients undergoing hand surgery.Methods:One hundred patients undergoing hand surgery were selected and randomly divided into two groups(n=50): the parecoxib sodium group(Group P) and the control group(Group C).After the success of infraclavicular brachial plexus block,patients in Group P were administered one bolus of parecoxib sodium(40mg,diluted by 2mL N.S.) intravenously 15 minutes before the beginning of operation,while those in Group C were injected N.S.by the same volume.VAS(visual analogue scale) was performed at postoperative 6,8,12 and 24 hours respectively,meanwhile,time and VAS to first pain,the number of patients demanded painkiller,time and VAS to first analgesia demanded were recorded and the adverse reactions were observed as well within 24h after operation.Results: The VAS scores at postoperative 8 and 12 hours,the number of patients demanded painkiller,the VAS score to first analgesia demanded were all less in Group P than those in Group C(P<0.05),while there was no significant difference in incidence of adverse reactions between the two groups within 24h after operation(P>0.05).Conclusions: Parecoxib sodium combined with infraclavicular brachial plexus block is safe and effective on postoperative analgesic effects after hand surgery.Parecoxib sodium could be a good choice of perioperative multimodal analgesia techniques.",
        "keywords": [
            "Brachial plexus block",
            "Infraclavicular approach",
            "Postoperative analgesia",
            "Parecoxib sodium"
        ],
        "authors": [
            {
                "name": "WANG Zhuoqun",
                "org": " Department of Anesthesiology,Huashan Hospital,Fudan University,Shanghai ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": " Department of Anesthesiology,Huashan Hospital,Fudan University,Shanghai ,China"
            },
            {
                "name": "LIANG Weimin",
                "org": " Department of Anesthesiology,Huashan Hospital,Fudan University,Shanghai ,China"
            }
        ],
        "venue": "Chinese Journal of Clinical Medicine",
        "year": 2011
    },
    "9diug5bY": {
        "id": "9diug5bY",
        "title": "Effects of Various Prophylactic Solutions on Postoperative Cytomegalovirus Infection in Liver Transplant Recipients",
        "abstract": "Objective:To investigate the status of postoperative cytomegalovirus(CMV) infection among the liver transplant recipients and to evaluate the effects of prophylactic solutions on CMV infection after liver transplantation in China.Methods:All the clinical and follow-up data was retrospectively investigated in 309 liver transplantation patients from January 2004 to March 2007 in Liver Transplantation Center,Zhongshan Hospital,Fudan university.Results: In the preoperative CMV-seropositive recipients,the CMV infection rates in the three prophylactic groups(PG group) who have been treated with intravenous ganciclovir(GCV),acyclovir(ACV),GCV+ACV were 10.5%,15.9% and 7.9%,respectively.The incidences of the CMV disease were 10.5%,8.3% and 3.2%,which showed significant differences compared to those in the non-prophylactic group(NPG group,42.3% and 15.4%,P<0.01).One-year overall survival rates of the three PG groups were 86.8%,78.0% and 88.9%,respectively.There was statistical difference in one-year survival rate between GCV+ACV group and the NPG group(P<0.05).Conclusions: In the preoperative CMV-seropositive recipients,all the three different prophylactic methods can lower the incidence of CMV infection and CMV disease.Moreover,GCV+ACV prophylactic treatment can significantly increase one-year survival rate of liver transplantation patients.",
        "keywords": [
            "Ganciclovir",
            "Cytomegalovirus",
            "Aciclovir",
            "Prophylactic",
            "Liver transplantation"
        ],
        "authors": [
            {
                "name": "WANG Baoqing",
                "org": "Department of Respiratory Disease,Zhongshan Hospital,Fudan University,Shanghai ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Nuclear Medicine,Zhongshan Hospital,Fudan University,Shanghai ,China"
            },
            {
                "name": "ZHANG Hanzhi",
                "org": "Department of Respiratory Disease,Yangpu District Central Hospital,Shanghai ,China"
            },
            {
                "name": "ZHOU Jian",
                "org": "Department of Liver Surgery & Liver Cancer,Zhongshan Hospital,Fudan University,Shanghai ,China"
            },
            {
                "name": "HE Lixian",
                "org": "Department of Respiratory Disease,Zhongshan Hospital,Fudan University,Shanghai ,China"
            }
        ],
        "venue": "Chinese Journal of Clinical Medicine",
        "year": 2013
    },
    "98c31QEG": {
        "id": "98c31QEG",
        "title": "A novel ensemble decision tree approach for mining genes coding ion channels for cardiopathy subtype",
        "abstract": "Ion channels are critical for normal physiological function of humans and their functional abnormality may cause many disorders named channelopathy. Meanwhile, they are one of the few proteins that can be efficiently regulated by small molecule drugs, so they are ideal candidates for drug targets. Upon these viewpoints, it is known that research on ion channels will bring great scientific and practical value. Here, we applied a novel ensemble decision tree approach based on mining genes encoding the ion channels. Using this ensemble method, we analyzed an oligo array data set concerning the human cardiopathy which investigated by Medical College of Harvard University. By analyzing 57 samples and 1172 genes related to ion channels and other transmembrane proteins, we demonstrated that the ensemble approach can efficiently mine out disease related CACNA genes.",
        "keywords": [
            "mining gene",
            "ensemble method",
            "ensemble approach",
            "human cardiopathy",
            "functional abnormality",
            "novel ensemble decision tree",
            "ion channel",
            "drug target",
            "harvard university",
            "cacna gene",
            "cardiopathy subtype",
            "medical college",
            "drug targeting",
            "decision tree",
            "transmembrane protein"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": ",Department of Bioinformatics, Harbin Medical University, Harbin, P.R. China"
            },
            {
                "name": "Xia Li",
                "org": "Department of Bioinformatics, Harbin Medical University, Harbin, P.R. China"
            },
            {
                "name": "Wei Jiang",
                "org": "Department of Bioinformatics, Harbin Medical University, Harbin, P.R. China"
            },
            {
                "name": "Yanqiu Wang",
                "org": "Department of Bioinformatics, Harbin Medical University, Harbin, P.R. China"
            },
            {
                "name": "Chuanxing Li",
                "org": "Department of Bioinformatics, Harbin Medical University, Harbin, P.R. China"
            },
            {
                "name": "Qiuju Wang",
                "org": "Institute of Otolaryngology, Chinese PLA General Hospital, Beijing, P.R. China"
            },
            {
                "name": "Shaoqi Rao",
                "org": "Department of Bioinformatics, Harbin Medical University, Harbin, P.R. China"
            }
        ],
        "venue": "Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)",
        "year": 2006
    },
    "JxWRTXYh": {
        "id": "JxWRTXYh",
        "title": "Analysis of sib-pair IBD profiles and genomic context for identification of the relevant molecular signatures for alcoholism",
        "abstract": "Recent advances in SNPs that allow genome-wide profiling of complex biological phenotypes have offered the golden opportunities to unravel the high-order mechanisms and have also motivated development of the corresponding analysis strategies. Here, we design four novel comprehensive association criteria concerning both informatics of IBD statistic and genomic context. Application of these criteria along with sliding window and permutation test to 100 simulated replicates for two American populations to extract the relevant SNPs for alcoholism from sib-pair IBD profiles of pedigrees demonstrates that the proposed new approaches have successfully identified most of the simulated true loci, thus implicating that IBD statistic and genomic context could be used as the informatics for mining the underlying genes for complex human diseases. Compared with the classical Haseman-Elston method, our strategy is more efficient and simpler.",
        "keywords": [
            "ibd statistic",
            "sib-pair ibd profile",
            "complex biological phenotypes",
            "american population",
            "relevant snps",
            "genomic context",
            "corresponding analysis strategy",
            "relevant molecular signature",
            "simulated true locus",
            "complex human disease",
            "classical haseman-elston method",
            "correspondence analysis",
            "sliding window",
            "permutation test"
        ],
        "authors": [
            {
                "name": "Chuanxing Li",
                "org": "Department of Bioinformatics, Harbin Medical University, Harbin, P.R. China"
            },
            {
                "name": "Lei Du",
                "org": "Department of Bioinformatics, Harbin Medical University, Harbin, P.R. China"
            },
            {
                "name": "Xia Li",
                "org": ",Department of Bioinformatics, Harbin Medical University, Harbin, P.R. China"
            },
            {
                "name": "Binsheng Gong",
                "org": "Department of Bioinformatics, Harbin Medical University, Harbin, P.R. China"
            },
            {
                "name": "Jie Zhang",
                "org": "Department of Bioinformatics, Harbin Medical University, Harbin, P.R. China"
            },
            {
                "name": "Shaoqi Rao",
                "org": ",Department of Bioinformatics, Harbin Medical University, Harbin, P.R. China"
            }
        ],
        "venue": "Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)",
        "year": 2006
    },
    "pBClpT19": {
        "id": "pBClpT19",
        "title": "Association research on potassium channel subtypes and functional sites",
        "abstract": "Potassium channels, a goup of membrane proteins and found in virtually all cells, are of crucial physiological importance for understanding cell biology and channelopathy. Studying the association of channel subtypes with their functional sites, and mining the functional sites mostly relevant to channel subtypes, can not only enhance molecular classification of potassium channels but only provide some clues for the functional targets. Here, we proposed to use functional sites profiles as features, where the functional sites are often used to characterize ion channels in biomedical research domains. We employed a novel integrated decision method to recognize the functional sites subset that is mostly relevant to the differentiation of potassium channel subtypes.",
        "keywords": [
            "functional target",
            "cell biology",
            "functional sites profile",
            "potassium channel subtypes",
            "functional site",
            "association research",
            "ion channel",
            "channel subtypes",
            "biomedical research domain",
            "functional sites subset",
            "potassium channel",
            "membrane protein"
        ],
        "authors": [
            {
                "name": "Peng Wu",
                "org": "Department of Bioinformatics, Harbin Medical University, Harbin, P.R. China"
            },
            {
                "name": "Xia Li",
                "org": ",Department of Bioinformatics, Harbin Medical University, Harbin, P.R. China"
            },
            {
                "name": "Shaoqi Rao",
                "org": ",Department of Bioinformatics, Harbin Medical University, Harbin, P.R. China"
            },
            {
                "name": "Wei Jiang",
                "org": "Department of Bioinformatics, Harbin Medical University, Harbin, P.R. China"
            },
            {
                "name": "Chuanxing Li",
                "org": "Department of Bioinformatics, Harbin Medical University, Harbin, P.R. China"
            },
            {
                "name": "Jie Zhang",
                "org": "Department of Bioinformatics, Harbin Medical University, Harbin, P.R. China"
            }
        ],
        "venue": "ICIC",
        "year": 2006
    },
    "Temg7su4": {
        "id": "Temg7su4",
        "title": "B7-H4 gene polymorphisms are associated with sporadic breast cancer in a Chinese Han population.",
        "abstract": "B7-H4, a co-inhibitory molecule of the B7 family, can restrain T cell proliferation, cytokine secretion and the development of cytotoxicity. B7-H4 is expressed in tumor tissues at a higher level than in normal tissues, and has a potential effect to protect tumors from anti-tumor immune responses. This case-control study was carried out to determine the potential influences of B7-H4 gene polymorphisms on the susceptibility and progression of breast cancer in Han women of Northeast China.We genotyped three B7-H4 variants (rs10754339, rs10801935 and rs3738414) and tagged all common haplotypes (frequency greater than or equal to 1%) in a Chinese population consisting of 500 breast cancer cases and 504 control individuals matched for age. Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) technique was used to determine the genotypes.Our data indicated that, compared with the common genotype and allele of each SNP, the rs10754339 AG genotype and G allele showed a significantly increased risk of breast cancer (OR = 1.455, 95% CI 1.119-1.892; OR = 1.325, 95% CI 1.073-1.637, respectively). The rs10801935 CC genotype, the rs3738414 AA genotype and the rs3738414 A allele were associated with a significantly decreased risk of breast cancer (OR = 0.328, 95% CI 0.145-0.739; OR = 0.412, 95% CI 0.203-0.835; OR = 0.698, 95% CI 0.564-0.864, respectively). Additionally, the rs10754339 GG genotype was significantly associated with lymph node metastasis and PR status, and the G allele and the AG genotype were respectively associated with lymph node metastasis and ER status. In haplotype analysis, we observed that compared with the AAG haplotype, the AAA haplotype showed a significantly decreased risk of breast cancer (OR = 0.689, 95% CI 0.539-0.881), but the GAG haplotype was associated with a significantly increased risk of breast cancer (OR = 1.511, 95% CI 1.125-2.031). And the AAA and the GCG haplotypes also respectively have significant influences on tumor size and ER status.These results suggest that B7-H4 gene polymorphism may contribute to the sporadic breast cancer risk and prognosis in Chinese Han women.",
        "keywords": [
            "correlation",
            "breast cancer",
            "alleles",
            "genes",
            "haplotypes",
            "statistical analysis",
            "genetic variation",
            "genotypes",
            "gene polymorphism",
            "restriction fragment length polymorphism",
            "stem cells",
            "cell proliferation",
            "oncology",
            "polymerase chain reaction",
            "cancer research",
            "case control study",
            "internal medicine"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Department of Immunology, Harbin Medical University, Harbin, Heilongjiang, PR China|Institute of Cancer Prevention and Treatment, Harbin Medical University, Harbin, Heilongjiang, PR China"
            },
            {
                "name": "Mingyan Zhang",
                "org": "Department of Immunology, Harbin Medical University, Harbin, Heilongjiang, PR China"
            },
            {
                "name": "Wei Jiang",
                "org": "Department of Bioinformatics, Harbin Medical University, Harbin, Heilongjiang, PR China"
            },
            {
                "name": "Lihong Wang",
                "org": "Institute of Cancer Prevention and Treatment, Harbin Medical University, Harbin, Heilongjiang, PR China"
            },
            {
                "name": "Zhenkun Fu",
                "org": "Department of Immunology, Harbin Medical University, Harbin, Heilongjiang, PR China"
            },
            {
                "name": "Dalin Li",
                "org": "Department of Surgery, the Third Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, PR China"
            },
            {
                "name": "Da Pang",
                "org": "Institute of Cancer Prevention and Treatment, Harbin Medical University, Harbin, Heilongjiang, PR China|Department of Surgery, the Third Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, PR China"
            },
            {
                "name": "Dianjun Li",
                "org": "Department of Immunology, Harbin Medical University, Harbin, Heilongjiang, PR China|Institute of Cancer Prevention and Treatment, Harbin Medical University, Harbin, Heilongjiang, PR China"
            }
        ],
        "venue": "BMC cancer",
        "year": 2009
    },
    "YanhP5Aj": {
        "id": "YanhP5Aj",
        "title": "Realization and Optimization for the Scene of Virtual City",
        "abstract": "The application of virtual city′s scene is an important step to design virtual city.This paper describes the significance of constructing virtual city and depicts virtual reality modeling language.At the same time,using the mode of design actual example,the paper discusses the construction of the scene of virtual city on VRML,and points out optimization strategy in the scene of virtual city′s modeling aiming at the large file of VRML and the slow speed of rendering.It has some significance for reference to construct digital city.",
        "keywords": [
            "optimize",
            "virtual city",
            "scene",
            "construction",
            "VRML"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Faculty of Mechanical and Electrical Engineering,Kunming University of Science and Technology,Kunming,,China"
            },
            {
                "name": "XU Wu",
                "org": "Faculty of Physics and Electronics,Yunnan University of the Nationalities,Kunming,,China"
            }
        ],
        "venue": "Modern Electronics Technique",
        "year": 2007
    },
    "ybQcGKvF": {
        "id": "ybQcGKvF",
        "title": "Designing experiment teaching and an example analysis",
        "abstract": "The paper analyses the form of designing experiment,and illuminates the implementation of designing experiment teaching.Through analyzing an example of PLC's experiment teaching,it shows that designing experiment teaching can improve students' ability of innovation in the engineer practice and research;can make student receive the education of scientific methodology and attitude;can make teacher extend thinking methods, update knowledge,and achieve that teaching benefits teachers as well as students.",
        "keywords": [
            "designing experiment",
            "experiment teaching",
            "example analysis"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Faculty of Mechanical and Electrical Engineering,Kunming University of Science and Technology,Kunming ,China"
            },
            {
                "name": "XU Wu",
                "org": "Faculty of Physics and Electronics,Yunnan University of the Nationalities,Kunming ,China"
            }
        ],
        "venue": "Experimental Technology and Management",
        "year": 2007
    },
    "byJZ4qQW": {
        "id": "byJZ4qQW",
        "title": "Application of SPC3 in Design of Profibus-DP Intelligent Slave Station",
        "abstract": "Profibus interface to connect field equipment with field bus in industrial control field and to realize distributed control.This paper introduces the basic characteristics of Profibus field bus and the communication interface chip of intelligent slave,and describes the interface design between SPC3 and AT89C52 and the software design of the intelligent slave.The intelligent slave based on SPC3 has the data acquisition and transfer function,and it has a broad application prospect in industrial control field.",
        "keywords": [
            "intelligent slave",
            "field-bus",
            "SPC3",
            "AT89C52"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Faculty of Mechanical and Electrical Engineering,Kunming University of Science and Technology,Kunming,,China"
            },
            {
                "name": "WANG Zheng",
                "org": "China Tobacco Yunnan Industrial Corporation,Kunming,,China"
            },
            {
                "name": "GUO Tianle",
                "org": "Kunming Roleeteen Electronics System Company Limited,Kunming,,China"
            }
        ],
        "venue": "Modern Electronics Technique",
        "year": 2008
    },
    "TGqKOGLY": {
        "id": "TGqKOGLY",
        "title": "Opening Experimental Teaching's Mode",
        "abstract": "Opening laboratory is the requirement for advancing teaching innovation and improving the level of teaching.To open laboratory in high efficiency and continuable way,it must effectually construct the mode of opening laboratory teaching.This paper pointed out the meaning of opening laboratory,and expatiated the construction of the mode.Through the practice of opening laboratory,it was found opening laboratory not only can make full use of laboratory resources and improve the level of teaching,but also helps to form new mode of cultivating high-level and innovation talents.",
        "keywords": [
            "teaching mode",
            "opening",
            "innovation",
            "experimental teaching"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "School of Mechanical and Electrical Engineering,Kunming University of Science and Technology,Kunming ,China"
            },
            {
                "name": "ZHANG Zhong-yan",
                "org": "School of Mechanical and Electrical Engineering,Kunming University of Science and Technology,Kunming ,China"
            },
            {
                "name": "NIU Xiao",
                "org": "School of Mechanical and Electrical Engineering,Kunming University of Science and Technology,Kunming ,China"
            }
        ],
        "venue": "Research and Exploration in Laboratory",
        "year": 2008
    },
    "p5QkYj4N": {
        "id": "p5QkYj4N",
        "title": "A Signaling Game of Selecting Projects in Venture Capital",
        "abstract": "The influence of the signal (commerce plan), which is passed from new companies to the venture capital companies, is analyzed. The importance of commerce plan during the course of venture capital companies selecting new companies is pointed out by the signaling game model. Correlation advices are presented to the venture capital companies when they select projects. Clues and suggestions are provided for the venture capital companies to evaluate venture and anticipatory in investment return more positively.",
        "keywords": [
            "commerce plan",
            "signaling game",
            "venture capital"
        ],
        "authors": [
            {
                "name": "Zhang Jie",
                "org": "College of International Business,Hohai University,Nanjing ,China"
            }
        ],
        "venue": "Value Engineering",
        "year": 2005
    },
    "1HGmVRe7": {
        "id": "1HGmVRe7",
        "title": "Researches on flexible decision-making of investment into water resources projects based on real option",
        "abstract": "With regard to the characteristics of investment into water resources projects,the theory and method of real option are employed to study flexible problems in decision-making of investment into water resources projects under the condition of uncertainty.Take a large water transfer project as an example,the flexible decision-making model based on real option is established.Effect of various uncertain factors on the flexibility of projects and their decision-making are analyzed by use of numerical analysis.A new method is thus provided.",
        "keywords": [
            "investment into water resources project",
            "real option",
            "decision-making",
            "flexibility"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "State Key Laboratory of Hydrology,Water Resources and Hydraulic Engineering,Hohai University,Nanjing ,China"
            }
        ],
        "venue": "Journal of Economics of Water Resources",
        "year": 2007
    },
    "q2EqN7Vp": {
        "id": "q2EqN7Vp",
        "title": "Comparative Study on Water Right Trade Management",
        "abstract": "Water right trade is one of the most important means to solve water shortage problem and to optimize the allocation of water resources.Water right trade is still in the exploratory phase in our country.Through the comparative study on the water right trade between our country and foreign countries,the key problem in the water right trade is concluded that is original water right allocation,the water right system and the price of water right trade.The development proposal of water right trade is put forward that is establishing and improving the corresponding water right trade system,strengthening the unified management of river basin,allocating the original water right,and introducing the water right option trade.",
        "keywords": [
            "original water right",
            "water price",
            "water right trade",
            "water right option"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "State Key Laboratory of Hydrology Water Resource and Hydraulic Engineering,Hohai University,Nanjing ,China"
            },
            {
                "name": "WANG Ji-gan",
                "org": "State Key Laboratory of Hydrology Water Resource and Hydraulic Engineering,Hohai University,Nanjing ,China"
            }
        ],
        "venue": "Ecological Economy",
        "year": 2008
    },
    "flyQWRhX": {
        "id": "flyQWRhX",
        "title": "Social risk and management modes of South-to-North Water Transfer Project during its operation period",
        "abstract": "In order to realize the scientific management of social risk of Southto-North Water Transfer Project during its operation period,the social relations of South-to-North Water Transfer Project during its operation period were analyzed.The social risk management of South-to-North Water Transfer Project during its operation period was studied by use of the policy science theory.The management modes should include the policy-making,implementation and evaluation of the social risk.The 4 components for the social risk management policy-making model of South-to-North Water Transfer Project during its operation period based on the Agent were discussed.The policy implementation modes of the social risk during its operation period were designed.",
        "keywords": [
            "risk management",
            "policy science",
            "social risk",
            "South-to-North Water Transfer Project"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "State Key Laboratory of Hydrology-Water Resources and Hydraulic Engineering,Hohai University,Nanjing ,China"
            }
        ],
        "venue": "Journal of Economics of Water Resources",
        "year": 2009
    },
    "LbAU2jhO": {
        "id": "LbAU2jhO",
        "title": "Analysis of Anaphylactic Shock Induced by Azithromycin Intravenus Injection",
        "abstract": "OBJECTIVE:To analyze and statis the anaphylactic shock cases induced by azithromycin intro venous injection which reported by literatures in China.To warn the physicists to detect its adverse drug reaction,and prevent the happening of serious incidents.METHODS:We searched the literatures which reported the cases of anaphylactic shock induced by azithromycin through CNKI and PUBMED database,and connected with the ADR in our hospital.Then we find out the rules and characteristic of anaphylactic shock induced by azithromycin.RESULTS:We have collected 20 articles which reported anaphylactic shock cases induced by azithromycin include 51 cases.The average age is 38.6,and 4 out of 51 caused death,the mortality rate is 7.8%.CONCLUSION:Anaphylactic shock cases induced by azithromycin is connected with the drug delivery way and delivery rate,and have little relativity with the essential disease,gender,age and dose.",
        "keywords": [
            "Literatures analysis",
            "Azithromycin",
            "Macrolide",
            "Anaphylactic shock"
        ],
        "authors": [
            {
                "name": "ZHAO Chun-li",
                "org": "Department of Pharmacy,Beijing Tongren Hospital Affiliated to Capital Medical University,Beijing ,China"
            },
            {
                "name": "DING Jian-jun",
                "org": "Department of Pharmacy,Beijing Tongren Hospital Affiliated to Capital Medical University,Beijing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Pharmacy,Tiantan Hospital Affiliated to Capital Medical University,Beijing ,China"
            },
            {
                "name": "CHEN Li",
                "org": "Department of Pharmacy,Tiantan Hospital Affiliated to Capital Medical University,Beijing ,China"
            },
            {
                "name": "GAO Ying-chang",
                "org": "Department of Pharmacy,Tiantan Hospital Affiliated to Capital Medical University,Beijing ,China"
            },
            {
                "name": "CUI Xiang-li",
                "org": "Department of Pharmacy,Tiantan Hospital Affiliated to Capital Medical University,Beijing ,China"
            }
        ],
        "venue": "Evaluation and Analysis of Drug-Use in Hospitals of China",
        "year": 2008
    },
    "I2NyllyJ": {
        "id": "I2NyllyJ",
        "title": "Application of fish oil lipid emulsion for parenteral nutrition in critical illness",
        "abstract": "Use of fish oil lipid emulsions,which are rich inω-3 lip- ids,in critical ill patients may exert an effect to reduce ventilation time, mortality,antibiotic demand,and length of stay.ω-3 Fatty acid con- tained in fish oil has beneficial properties of reduction of inflammatory re- action and immunological modulation.Using a high-dose short-term infusion of fish oil lipid emulsion,rapid immunologic changes and effects on the endotoxin-induced stress response may be achieved.This review discussed the current advances in parenteral administration of fish oil lip- id emulsion in the intensive care patients.",
        "keywords": [
            "parenteral nutrition",
            "ω-3 fatty acid",
            "critical illness",
            "fish oil lipid emulsion"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Department of Pharmacy,Beijing Tiantan Hospital Affiliated to Capital Medical University,Beijing ,China"
            },
            {
                "name": "GAO Ying-chang",
                "org": "Department of Pharmacy,Beijing Tiantan Hospital Affiliated to Capital Medical University,Beijing ,China"
            },
            {
                "name": "CUI Xiang-li",
                "org": "Department of Pharmacy,Beijing Tiantan Hospital Affiliated to Capital Medical University,Beijing ,China"
            },
            {
                "name": "REN Shu-ping",
                "org": "Department of Pharmacy,Beijing Tiantan Hospital Affiliated to Capital Medical University,Beijing ,China"
            }
        ],
        "venue": "The Chinese Journal of Clinical Pharmacology",
        "year": 2008
    },
    "QgN3y0L7": {
        "id": "QgN3y0L7",
        "title": "Current status of clinical pharmacist",
        "abstract": "In recent years,great progress has been made in Chinese clinical pharmacy. Development mode and valuable experience of foreign countries have been positively learned,at the same time there still exist many distinct characters belonging to our country. Objectively to say,all of these changes put great impacts on our management and organizing mode of traditional hospital pharmacy,meanwhile this promote every pharmaceutical personnel in hospital to think over the development of hospital pharmacy in new era. Here the current progress status,problem,challenge,job disturbance and development tendency in the future of clinical pharmacy were reviewed and prospected to provide reference for promoting the development of clinical pharmacy.",
        "keywords": [
            "medication safety",
            "clinical pharmacist",
            "clinical pharmacy service"
        ],
        "authors": [
            {
                "name": "CUI Xiang-li",
                "org": "Department of Pharmacy,Tiantan Hospital Affiliated to Capital Medical University,Beijing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Pharmacy,Tiantan Hospital Affiliated to Capital Medical University,Beijing ,China"
            },
            {
                "name": "ZHAO Zhi-gang",
                "org": "Department of Pharmacy,Tiantan Hospital Affiliated to Capital Medical University,Beijing ,China"
            }
        ],
        "venue": "Chinese Journal of New Drugs",
        "year": 2009
    },
    "NJ6b3FL5": {
        "id": "NJ6b3FL5",
        "title": "Analysis of Utilization of Antidepressant Drugs in Our Hospital During 2004-2007",
        "abstract": "Objective:To appraise the current situation and the developmental trend of antidepressant drugs in our hospital.Method:The antidepressant drugs in our hospital during 2004-2007 were analyzed retrospectively in terms of drug varieties,consumption quantity,consumption sum,DDDs,daily cost,etc.Result:The consumption sum and DDDs of the antidepressant drugs increased but their daily cost decreased.The consumption sum of the antidepressant drugs decreased in 2006 because of the measure of the drug proportion control.Conclusion:Paroxetine and fluoxetine dominates the first place in terms of clinical application of antidepressants.Furthermore,the application of the new type of antidepressants has been on the rise.",
        "keywords": [
            "Drug utilization",
            "Antidepressant",
            "DDDs",
            "Daily cost"
        ],
        "authors": [
            {
                "name": "Tian Deqiang",
                "org": " Dept.of Pharmacy,Tiantan Hospital Affiliated to Capital University of Medical Sciences,Beijing ,China"
            },
            {
                "name": "Zhang Jie",
                "org": " Dept.of Pharmacy,Tiantan Hospital Affiliated to Capital University of Medical Sciences,Beijing ,China"
            },
            {
                "name": "Zhao Zhigang",
                "org": " Dept.of Pharmacy,Tiantan Hospital Affiliated to Capital University of Medical Sciences,Beijing ,China"
            },
            {
                "name": "Wang Liwen",
                "org": " Dept.of Pharmacy,Tiantan Hospital Affiliated to Capital University of Medical Sciences,Beijing ,China"
            }
        ],
        "venue": "Chinese Journal of Pharmacoepidemiology",
        "year": 2009
    },
    "NYPli3d6": {
        "id": "NYPli3d6",
        "title": "The effectiveness of restricting drug income proportion in Beijing Tiantan Hospital and discussion on coordinating method",
        "abstract": "Objective: To study the effectiveness of restricting drug income proportion in Beijing Tiantan Hospital and put forward corresponding coordinating methods. Methods: The statistical results of drug income proportion in the hospital from January 2006 to December 2008 were analyzed by taking advantage of the hospital information system. Results: The drug income proportion was decreased after restricting the highest drug income proportions in each department. Conclusion: Restriction of drug income proportion is effective. Decrease in medicine expenses can benefit the patients.",
        "keywords": [
            "Cost control",
            "Drug income proportion",
            "Fees",
            " pharmaceutical",
            "Health care reform"
        ],
        "authors": [
            {
                "name": "WANG Li-wen",
                "org": "Capital Medical University China(Capital University of Medical Sciences,Capital Medical University),Beijing,China"
            },
            {
                "name": "ZHANG Li-ren",
                "org": "Wuhai People's Hospital(Wuhai People's Hospital),,China"
            },
            {
                "name": "Ke Yang",
                "org": "Peking University(Peking University),Beijing,China"
            },
            {
                "name": "ZHU Chuan-jun",
                "org": "Peking University(Peking University),Beijing,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Capital Medical University China(Capital University of Medical Sciences,Capital Medical University),Beijing,China"
            },
            {
                "name": "Hui Ying Chen",
                "org": "Capital Medical University China(Capital University of Medical Sciences,Capital Medical University),Beijing,China"
            },
            {
                "name": "ZHAO Zhi-gang",
                "org": "Capital Medical University China(Capital University of Medical Sciences,Capital Medical University),Beijing,China"
            }
        ],
        "venue": "Pharmaceutical Care and Research",
        "year": 2009
    },
    "TkI1FeH4": {
        "id": "TkI1FeH4",
        "title": "Evaluation on the establishment of levothyroxine-induced cardiomyopathy rabbit models with quantitative tissue velocity imaging",
        "abstract": "Objective To assess the value of quantitative tissue velocity imaging (QTVI) in monitoring the establishment of levothyroxine-induced cardiomyopathy models on rabbits. Methods Thirty New Zealand purebred rabbits were divided into experimental group (n=20) and control group (n=10). Hyperthyroidism models were established by peritoneal injection of levothyroxine (L-Thy) in experimental group (45μg/). The same dose of saline was given to rabbits in control group for 4 weeks. QTVI and conventional echocardiographic parameters were obtained at the beginning day and 1, 2, 4 weeks in two groups. According to the changes of ultrasound parameters, the rabbits of experimental group were divided into two subgroups: Concentric hypertrophy (CH) subgroup and eccentric hypertrophy (EH) subgroup. Results At the first week, left ventricular ejection fraction (LVEF), fractional shortening (LVFS), mitral inflow peak velocity (E), average mitral annularsystolic peak velocity (Vs) and acceleration (a) increased obviously than before injection in experimental group (P<0.01). At the second week, posterior wall thickness at end diastole (PWT d), interventricular septal thickness at end diastole (IVSTd) and left ventricular mass index (LVMI) increased obviously than before injection in experimental group and control group (P<0.05), and the average mitral annular early diastolic velocity (Ve) was significantly lower (P<0.01). Compared with control group, the average Ve was significantly lower in CH subgroup (P<0.01), while LVEF, LVFS, average Vs, a and average Ve were significantly lower in EH subgroup (P<0.01). Conclusion QTVI is valuable in the assessment of establishing levothyroxine-induced cardiomyopathy models on rabbits.",
        "keywords": [
            "Cardiomyopathy",
            " levothyroxine-induced",
            "Echocardiography",
            "Quantitative tissue velocity imaging",
            "Rabbits"
        ],
        "authors": [
            {
                "name": "WANG Ya-juan",
                "org": "The Second Affiliated Hospital of Dalian Medical Uuniversity(The Second Affiliated Hospital of Dalian Medical Uuniversity),Dalian,China"
            },
            {
                "name": "LI Guang-sen",
                "org": "The Second Affiliated Hospital of Dalian Medical Uuniversity(The Second Affiliated Hospital of Dalian Medical Uuniversity),Dalian,China"
            },
            {
                "name": "SUN Yan-hong",
                "org": "The Second Affiliated Hospital of Dalian Medical Uuniversity(The Second Affiliated Hospital of Dalian Medical Uuniversity),Dalian,China"
            },
            {
                "name": "Jie Zhang",
                "org": "The Second Affiliated Hospital of Dalian Medical Uuniversity(The Second Affiliated Hospital of Dalian Medical Uuniversity),Dalian,China"
            },
            {
                "name": "WANG Wei-dong",
                "org": "The Second Affiliated Hospital of Dalian Medical Uuniversity(The Second Affiliated Hospital of Dalian Medical Uuniversity),Dalian,China"
            },
            {
                "name": "BI Wen-jun",
                "org": "The Second Affiliated Hospital of Dalian Medical Uuniversity(The Second Affiliated Hospital of Dalian Medical Uuniversity),Dalian,China"
            }
        ],
        "venue": "Chinese Journal of Interventional Imaging and Therapy",
        "year": 2011
    },
    "tUANxvIz": {
        "id": "tUANxvIz",
        "title": "Levels of serum cardic troponin in the different geometric patterns of left ventricle in rabbits with hyperthyroid cardiomyopathy",
        "abstract": "Objective To observe and study the level of serum cardiac troponin (cTn-I) in the different geometric patterns of left ventricle in rabbits with hyperthyroid cardiomyopathy. Methods Thirty New Zealand purebred rabbits were randomly divided into two groups: control group (n=10) and experimental group (n=20). Hyperthyroidism animal model was established by peritoneal injection of Levothyroxine (L-Thy) in experimental group. According to the ultrasound parameter changes, the ventricular geometries of experimental group were divided into two groups: concentric hypertrophy (CH) and eccentric hypertrophy(EH). Each groups underwent conventional echocardiogram, and evaluate cTn-I values. Results In CH group, the LVMI and RWT increased obviously(P<0.01). In EH group,the LVMI increased obviously(P<0.01), but RWT did not change significantly(P>0.05). EF and FS were significantly lower in EH group than those of the control group (P<0.01). The cTn-I in blood of CH group was conspicuously higher than that of the control group (P<0.01). The cTn-I in blood of EH group was conspicuously higher than that of the control group and CH group (P<0.01). The serum cTn-I was positive correlatd with LVMI. The pathological examination demonstrated that the damages increased in EH group than that in CH group. Conclusions Serum cTn-I in the different geometric patterns of left ventricle in rabbits with hyperthyroid cardiomyopathy increased in varying degree and the elevation of cTn-I is in accordance with the degree of pathological injury.",
        "keywords": [
            "Left ventricular morphology",
            "Rabbits",
            "Troponin I",
            "Cardiomyopathies"
        ],
        "authors": [
            {
                "name": "WANG Ya-juan",
                "org": ".Department of Ultrasonography,The Second Affiliated Hospital of Dalian Medical University,Dalian ,China"
            },
            {
                "name": "LI Guang-sen",
                "org": ".Department of Ultrasonography,The Second Affiliated Hospital of Dalian Medical University,Dalian ,China"
            },
            {
                "name": "SUN Yan-hong",
                "org": ".Department of Ultrasonography,The Second Affiliated Hospital of Dalian Medical University,Dalian ,China"
            },
            {
                "name": "WANG Wei-dong",
                "org": ".Department of Ultrasonography,The Second Affiliated Hospital of Dalian Medical University,Dalian ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": ".Department of Ultrasonography,The Second Affiliated Hospital of Dalian Medical University,Dalian ,China"
            },
            {
                "name": "BI Wen-jun",
                "org": ".Department of Ultrasonography,The Second Affiliated Hospital of Dalian Medical University,Dalian ,China"
            }
        ],
        "venue": "Chinese Journal of Clinicians(Electronic Edition)",
        "year": 2011
    },
    "qvNfYseS": {
        "id": "qvNfYseS",
        "title": "Evaluation of left ventricular systolic function of different geometic patterns in rabbits with hyperthyroid cardiomyopathy by tissue tracking",
        "abstract": "Objective To evaluate left ventricular systolic function of different geometic patterns in rabbits with hyperthyroid cardiomyopathy by tissue tracking(TT). Methods Thirty New Zealand purebred rabbits were randomly divided into control group(n=10)and experimental group(n=20).Hyperthyroidism animal model was established by intraperitoneal injection of Levothyroxine (45 μg·kg ﹣1 ·d ﹣1 ×28 d)in experimental group. According to ultrasonic parameters,the ventricular geometries of experimental group were divided into concentric hypertrophy (CH group)and eccentric hypertrophy (EH group). The systolic mitralannular peak displacement(Ds) was measured by TT. The systolic mitralannular displacement(Dm) was measured by M-mode echocardiography. The parameters of LVEF and FS were calculated by Teichholtz’s formula. The parameters in all groups were compared. Results In 2,3 weeks,2 of 20 rabbits in experimental group died,and eventually 18 rabbits were included in the study,including 7 in CH group and 11 in EH group. Compared with control group and CH group,the Ds,Dm,LVEF and FS of mitralannular in Eh group decreased (P<0.01). Compared with control group,the Ds and Dm of mitralannular decreased,while LVEF,FS did not significantly reduce. Conclusion TT can assess accurately left ventricular systolic function of different geometic patterns in rabbits with hyperthyroid cardiomyopathy.",
        "keywords": [
            "Ventricle function",
            "Cardiomyopathy",
            "Tissue tracking",
            "left",
            "hyperthyroid",
            "Rabbit"
        ],
        "authors": [
            {
                "name": "WANG Weidong",
                "org": " Department of Ultrasound,the Second Affiliated Hospital of Dalian Medical University,Dalian ,China"
            },
            {
                "name": "LI Guangsen",
                "org": " Department of Ultrasound,the Second Affiliated Hospital of Dalian Medical University,Dalian ,China"
            },
            {
                "name": "WANG Yajuan",
                "org": " Department of Ultrasound,the Second Affiliated Hospital of Dalian Medical University,Dalian ,China"
            },
            {
                "name": "SUN Yanhong",
                "org": " Department of Ultrasound,the Second Affiliated Hospital of Dalian Medical University,Dalian ,China"
            },
            {
                "name": "BI Wenjun",
                "org": " Department of Ultrasound,the Second Affiliated Hospital of Dalian Medical University,Dalian ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": " Department of Ultrasound,the Second Affiliated Hospital of Dalian Medical University,Dalian ,China"
            }
        ],
        "venue": "Journal of Clinical Ultrasound in Medicine",
        "year": 2012
    },
    "Ukqactw0": {
        "id": "Ukqactw0",
        "title": "Evaluation of right ventricular function in alcoholic cardiomyopathy by quantitative tissue velocity imaging",
        "abstract": "Objective To evaluate the clinical value of right ventricular function by quantitative tissue velocity imaging(QTVI)in patients with alcoholic cardiomyopathy(ACM).Methods 35 patients with ACM group and 30 healthy adults(control group)were examined,and QTVI and conventional echocardiographic parameters were obtained in two groups.QTVI parameters were measured from the tricuspid annular systolic and diastolic velocity curves in apical four-chamber at the tricuspid anterior leaflet and septal leaflet of using QTVI,which included peak systolic velocity(Vs),peak early diastolic velocity(Ve),peak late diastolic velocity(Va),the ratio of Ve and Va(Ve/Va),and the Tei index was also calculated.To analysis the correlation study of lateral wall annulus Tei index and Vs,Ve and Ve/Va in ACM group.Results Compared with the control group,LVDd and RVEDd were significantly increased in ACM group(P<0.05),LVEF was significantly decreased(P<0.05),but there was no obviously difference in RVEF between two groups(P>0.05).Compared with the control group,Vs,Ve and Ve/Va obtained by QTVI were significantly decreased in ACM group(P<0.05).Tei index was significantly increased in ACM group than that of the control group(P<0.05).Correlation analysis showed that the lateral wall annulus Tei index was negatively correlated with Vs,Ve and Ve/Va in ACM group(P<0.05).Conclusions QTVI provides an effective and non-invasive tool to assess the right ventricular function in patients with ACM,which has important clinical value.",
        "keywords": [
            "Cardiomyopathy",
            "Quantitative tissue velocity imaging",
            "alcoholic",
            "right",
            "Ventricular function"
        ],
        "authors": [
            {
                "name": "GUO Li-juan",
                "org": ".Department of Ultrasound,The Second Affiliated Hospital of Dalian Medical University,Dalian ,China"
            },
            {
                "name": "LI Guang-sen",
                "org": ".Department of Ultrasound,The Second Affiliated Hospital of Dalian Medical University,Dalian ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": ".Department of Ultrasound,The Second Affiliated Hospital of Dalian Medical University,Dalian ,China"
            }
        ],
        "venue": "Chinese Journal of Clinicians(Electronic Edition)",
        "year": 2012
    },
    "aEumJeR2": {
        "id": "aEumJeR2",
        "title": "Evaluation of right ventricular longitudinal function in patients with alcoholic cardiomyopathy by two-dimensional strain imaging",
        "abstract": "AIM:To evaluate the right ventricular longitudinal function with two-dimensional strain imaging(2DSI) in patients with alcoholic cardiomyopathy(ACM).METHODS:Conventional echocardiography parameters and 2DSI parameters were examined in 32 ACM patients(ACM group) and 35healthy adults(control group).2DSI parameters were recorded from the displacement(D),strain(S)and strain rate(SRs) curves,which were obtained from basal to apical right ventricular free wall in apical four-chamber using 2DSI.Parameters of peak systolic longitudinal displacement(D),strain(S),systolic strain rate(SRs),early diastolic strain rate(SRe) and late diastolic strain rate(SRa) were included.RESULTS:Compared with control group,RVEDd significantly increased in ACM group(P <0.05),but no obvious difference was seen in RVEF between groups.Parameters of D,S,SRs,SRe and SRa of all right ventricular free wall segments obtained by 2DSI significantly decreased in ACM group(P<0.05,P<0.01).CONCLUSION;2DSI provides an effective and non-invasive tool to assess right ventricular longitudinal function in patients with ACM,which has important clinical value.",
        "keywords": [
            "ventricular function",
            "alcoholic cardiomyopathy",
            "right",
            "two-dimensional strain imaging"
        ],
        "authors": [
            {
                "name": "GUO Li-juan",
                "org": ""
            },
            {
                "name": "LI Guang-sen",
                "org": ""
            },
            {
                "name": "ZHANG Jie",
                "org": ""
            },
            {
                "name": "SHAN Guo-xin",
                "org": ""
            },
            {
                "name": "XU Rui",
                "org": ""
            }
        ],
        "venue": "Chinese Heart Journal",
        "year": 2013
    },
    "8iLEI8JO": {
        "id": "8iLEI8JO",
        "title": "Cardiomyocyte apoptosis of different left ventricular geometric patterns in rabbits with hyperthyroid cardiomyopathy",
        "abstract": "AIM:To study cardiomyocyte apoptosis and the expressions of bcl-2 and bax protein in levothyroxine-induced cardiomyopathy in rabbits with different patterns of left ventricular geometric models.METHODS:Thirty New Zealand purebred rabbits were stochastically divided into experimental group(n =20) and control group(n = 10).Hyperthyroidism models were established by peritoneal injection of levothyroxine(L-Thy) in experimental group[45 μg/(kg ? day)]for 4 weeks.The same dose of saline was given to rabbits in the control group for 4 weeks.Conventional echocardiographic parameters were obtained at the end of the fourth week in both groups and according to the changes of ultrasound parameters,the rabbits of experimental group were divided into two subgroups:concentric hypertrophy(CH) and eccentric hypertrophy(EH).All rabbits were executed 4 weeks later,myocardial tissue was obtained and cardiomyocytes were observed by transmission electron microscope.Apoptotic cardiomyocytes were detected using terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling(TUNEL) method and the expressions of bcl-2 and bax protein were determined by immunohistochemical method using mean absorbance.RESULTS:Many apoptotic cardiomyocytes were found in CH subgroup and EH subgroup by electron microscope,whereas no apoptotic cardiomyocytes were seen in the control group.Compared with that in the control group,the index of apoptotic cardiomyocytes increased significantly in both subgroups(P <0.01).The index in apoptotic cardiomyocytes of the EH subgroup was higher than in the CH subgroup(P <0.01).Compared with the control group,bcl-2 protein expression was significantly lower in the CH subgroup and EH subgroup(P < 0.01) and bcl-2 protein expression in the EH subgroup was lower than in the CH subgroup(P <0.01).The expression of bax protein was significantly higher in the CH subgroup and EH subgroup(P <0.01) and bax protein expression in the EH subgroup was higher than in the CH subgroup(P <0.01);bcl-2/bax was significantly lower in CH subgroup and EH subgroup(P <0.01).CONCLUSION:The degree of cardiomyocyte apoptosis is different in different patterns of left ventricular geometric models of levothyroxine-induced cardiomyopathy,indicating that cardiomyocyte apoptosis is an important pathological mechanism of levothyroxine-induced cardiomyopathy.The effect may be related to the downregulation of bcl-2 protein expression and upregulation of bax protein expression.",
        "keywords": [
            "rabbit",
            "apoptosis",
            "cardiomyopathies",
            "hyperthyroidism"
        ],
        "authors": [
            {
                "name": "WANG Wei-dong",
                "org": ""
            },
            {
                "name": "LI Guang-sen",
                "org": ""
            },
            {
                "name": "WANG Ya-juan",
                "org": ""
            },
            {
                "name": "BI Wen-jun",
                "org": ""
            },
            {
                "name": "ZHANG Jie",
                "org": ""
            }
        ],
        "venue": "Chinese Heart Journal",
        "year": 2013
    },
    "Rr4R4IgI": {
        "id": "Rr4R4IgI",
        "title": "Correlation of myocardial enzymes and cardiac function in rabbits with hyperthyroid cardiomyopathy",
        "abstract": "AIM: To study the correlation between the level of serum myocardial enzyme and cardiac function in rabbits with hyperthyroid cardiomyopathy. METHODS: Thirty New Zealand purebred rabbits were randomly divided into two groups: control group( n = 10) and experimental group( n = 20). Animal model of hyperthyroidism was established by peritoneal injection of levothyroxine( L-Thy) in the experimental group. According to the ultrasound parameter changes,ventricular geometries of the experimental group were divided into two groups: concentric hypertrophy( CH) and eccentric hypertrophy( EH).Each group underwent conventional echocardiography and myocardial enzyme values were evaluated.RESULTS: In the CH group,LVMI and RWT increased in an obvious manner( P < 0. 01). In the EH group,LVMI increased in an obvious manner( P < 0. 01),whereas RWT did not change significantly.Both EF and FS in the EH group were significantly lower than those in the control group( P < 0. 01).Serum CK-MB in the EH group was conspicuously higher than in the control group and CH group( P <0. 01). Pathological examination showed that the damage in the EH group was more severe than in the CH group. LVEF and LVFS were negatively correlated with myocardial enzyme in blood( r = 0. 393,P < 0. 05; r = 0. 423,P < 0. 05). CONCLUSION: Serum CK-MB in different geometric patterns of the left ventricle in rabbits with hyperthyroid cardiomyopathy increases to different degrees. Elevation of myocardial enzyme is associated with the degree of pathological injury and is significantly correlated with cardiac dysfunction.",
        "keywords": [
            "rabbit",
            "hyperthyroid cardiomyopathy",
            "left ventricular morphology",
            "myocardial enzyme"
        ],
        "authors": [
            {
                "name": "BI Wen-jun",
                "org": ""
            },
            {
                "name": "LI Guang-sen",
                "org": ""
            },
            {
                "name": "WANG Ya-juan",
                "org": ""
            },
            {
                "name": "WANG Wei-dong",
                "org": ""
            },
            {
                "name": "ZHANG Jie",
                "org": ""
            }
        ],
        "venue": "Chinese Heart Journal",
        "year": 2013
    },
    "eSYKpb13": {
        "id": "eSYKpb13",
        "title": "Special Equipment for Corrosion-Prevention of Steel Piles in Tidal Region",
        "abstract": "With the development of Chinese and international shipping industry, large-diameter steel pipe piles are now widely used in port construction. However, the repair and maintenance for steel piles after corrosion can not be carried out easily because of the lack of special equipment providing dry working condition for surface corrosion-prevention of steel piles. This paper puts forward a special equipment for this purpose, which may serve as a reference for similar projects.",
        "keywords": [
            "steel pipe pile",
            "raking pile",
            "anti-corrosive treatment",
            "dry-condition construction"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Shanghai Jiaotong University, Shanghai , China"
            }
        ],
        "venue": "Port & Waterway Engineering",
        "year": 2005
    },
    "27GMnpBC": {
        "id": "27GMnpBC",
        "title": "Scheduling Strategy of Process Sequence for Rewind Cell of Fiber Manufacturing",
        "abstract": "To enhance information feedback speed and the efficiency of planning execution for rewind cell of fiber manufacturing,a strategy considering information feedback speed and rewind process time in high priority was proposed.To support the strategy,the characteristics of product production of rewind cell were analyzed and the criteria of product classification were addressed.According to product classification,priority of different product type and scheduling principle were set.The evaluation criteria of scheduling were presented.By experiments,the advantages of scheduling strategy proposed were validated.",
        "keywords": [
            "scheduling strategy",
            "rewind cell",
            "evaluation",
            "fiber manufacturing"
        ],
        "authors": [
            {
                "name": "Zhang Jie",
                "org": "Shanghai Jiaotong University,Shanghai,"
            },
            {
                "name": "Fang Haisong",
                "org": "Shanghai Jiaotong University,Shanghai,"
            },
            {
                "name": "Cheng Yang",
                "org": "Shanghai Jiaotong University,Shanghai,"
            }
        ],
        "venue": "China Mechanical Engineering",
        "year": 2006
    },
    "QxfvsHWO": {
        "id": "QxfvsHWO",
        "title": "Dynamic Job Shop Scheduling Research Based on Event-driven Strategy and Changed-cycle-driven Strategy",
        "abstract": "Dynamic scheduling strategy of event-driven and cycle-driven based on changed-cycle rolling window technology is put forward.The syncretized ant system combined of the elitist ant strategy,best-worst ant system and phase-control system as the dynamic optimizing algorithm is given.The dynamic events such as job cancelled,urgent job,machine fault and variational production load based on the strategy and algo- rithm are studied.The simulation result shows effectiveness of the strategy and algorithm.",
        "keywords": [
            "changed-cycle rolling window technology",
            "event-driven",
            "cycle-driven",
            "syncretized ant system"
        ],
        "authors": [
            {
                "name": "LU Wei",
                "org": "Computer Integrated Manufacturing Institute,Shanghai Jiaotong University,Shanghai ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Computer Integrated Manufacturing Institute,Shanghai Jiaotong University,Shanghai ,China"
            }
        ],
        "venue": "Control Engineering of China",
        "year": 2007
    },
    "ySY95DNE": {
        "id": "ySY95DNE",
        "title": "Enterprise Informatization Evaluation System and Method",
        "abstract": "Through the research of the whole life cycle of enterprise informatization,an evaluation system is established,which can evaluate by stages.And evaluating through progressive method of AHP model gives a phase-in and an all-around result.More than one hundred companies have practiced,which get reasonable and comprehensive result.Totally,the evaluation system that is scientific,rational and more exercisable provides the enterprise timely feedback and improved information.",
        "keywords": [
            "Performance evaluation",
            "Enterprise informatization",
            "AHP",
            "whole life cycle"
        ],
        "authors": [
            {
                "name": "CHENG Yang",
                "org": "Institute of Computer Integrated Manufacturing,Shanghai Jiaotong University,Shanghai "
            },
            {
                "name": "ZHANG Jie",
                "org": "Institute of Computer Integrated Manufacturing,Shanghai Jiaotong University,Shanghai "
            },
            {
                "name": "QU Zhaorong",
                "org": "East China Institute of Computing Technology,Shanghai "
            }
        ],
        "venue": "Computer Engineering",
        "year": 2007
    },
    "9pZ36rAd": {
        "id": "9pZ36rAd",
        "title": "The short-term prediction method of throughput for En-entrant manufacturing system",
        "abstract": "The re-entrant manufacturing systems (RMS) under the high uncertain environment have the non-linear characteristic of time series in the throughput.GA & wavelet neural network based short-term prediction method of throughput is proposed.It makes the prediction model have the excellent toward feature of wavelet analysis and the self-study & self-adaptive characteristic of neural network.At the same time,the parameters of neural network are trained by the genetic algorithm,and the search behaviors of optimal process are enriched by using the characteristic of recessive concurrent and whole search of genetic algorithm so as to enhance the overall and local search capacity and efficiency.The case study of semiconductor production line is as experiment.The experimental results demonstrate the effectiveness of the above proposed method and it has precedence over the back propaga- tion (BP) of neural network in the prediction performance.",
        "keywords": [
            "re-entrant manufacturing systems",
            "neural network",
            "genetic algorithm",
            "prediction"
        ],
        "authors": [
            {
                "name": "CHEN Xue-fang",
                "org": "Computer Integrate Manufacturing Institution of Shanghai Jiao Tong University,Shanghai ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Computer Integrate Manufacturing Institution of Shanghai Jiao Tong University,Shanghai ,China"
            }
        ],
        "venue": "Manufacturing Automation",
        "year": 2008
    },
    "zA5bIVNS": {
        "id": "zA5bIVNS",
        "title": "The Application and Research of a Simulation-based Streamline Balance Method",
        "abstract": "In order to improve a real compressor assembly line,the rebuilt strategy based on a streamline balance method and the object oriented modeling technology is proposed.Firstly the simulation model of the compressor assembly line is set up and,the bottleneck is found out and analyzed with the the model.Secondly the optimal strategies based on streamline balance method are given and evaluated by the model.Finally one of the strategies causing a 10.39% accretion of the production capacity is selected to rebuild the assembly line,which strongly proved the effectiveness of the simulation technology and the reliability of the streamline balance method.",
        "keywords": [
            "streamline balance",
            "capacity",
            "eM-Plant simulation"
        ],
        "authors": [
            {
                "name": "ZHU Qiong",
                "org": "CIM Institute,Shanghai Jiaotong University,Shanghai ,China"
            },
            {
                "name": "CHEN Xue-fang",
                "org": "Mechanical and electronic Engineering department,Suzhou Vocational University,Suzhou ,China"
            },
            {
                "name": "TIAN Shi-yong",
                "org": "CIM Institute,Shanghai Jiaotong University,Shanghai ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "CIM Institute,Shanghai Jiaotong University,Shanghai ,China"
            }
        ],
        "venue": "Industrial Engineering and Management",
        "year": 2008
    },
    "564ewlJ2": {
        "id": "564ewlJ2",
        "title": "Electronic Assembly Industry MES Architecture and Technology Implementation",
        "abstract": "In order to meet demands of electronic assembly industry Manufacturing Executed System(MES),the MES software architecture of Web service is introduced,which is based on SOA.In order to develop MES software architecture,the implementation technologies of MES software architecture with workflow are researched.The frameworks of real-time visualization,real-time dynamic scheduling,and real-time process tracking of electronic assembly shop based on workflow are proposed.And the technology framework of MES software architecture is introduced based on the Web Services technology and J2EE development platform.The application of MES on a SMT shop shows that the software has well real-time,component-based,configuration and integration performance.",
        "keywords": [
            "Manufacturing Executed System(MES)",
            "workflow",
            "software architecture"
        ],
        "authors": [
            {
                "name": "WU Li-hui",
                "org": "Institute of Computer Integrated Manufacturing,Shanghai Jiaotong University,Shanghai "
            },
            {
                "name": "ZHANG Jie",
                "org": "Institute of Computer Integrated Manufacturing,Shanghai Jiaotong University,Shanghai "
            }
        ],
        "venue": "Computer Engineering",
        "year": 2009
    },
    "IfM9V6b7": {
        "id": "IfM9V6b7",
        "title": "Key Techniques of Workflow Based MES for Electronic Assembly Industry",
        "abstract": "The functions of manufacturing execution system (MES) of electronic assembly industry such as the real-time visualization,dynamic schedule,production process track,configurablility and integration are discused.The workflow technology based model of electronic assemble industry is proposed.A software architecture of workflow engine is constructed in MES software system.The workflow engine is implemented based on J2EE architecture and EJB component technology.The application of the electronic assembly MES in PCB assembly industry shows that both production efficiency and management level are greatly improved.",
        "keywords": [
            "electronic assembly",
            "manufacturing executed system",
            "workflow engine",
            "software architecture",
            "workflow"
        ],
        "authors": [
            {
                "name": "WU Li-hui",
                "org": "Institute of Computer Integrated Manufacturing,Shanghai Jiao Tong University,Shanghai ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Institute of Computer Integrated Manufacturing,Shanghai Jiao Tong University,Shanghai ,China"
            }
        ],
        "venue": "Control Engineering of China",
        "year": 2009
    },
    "elKdTflu": {
        "id": "elKdTflu",
        "title": "Radio Frequency Identification Middleware for PCB Assembly Process Tracking",
        "abstract": "With high automation level,PCB assembly industry is circumscribed by the product marking while it intends to improve its production tracking. To change this,this paper uses Radio Frequency Identification(RFID) to mark the materials and the products instead of barcode as before. It defines the functions of RFID middleware,defines the information exchange between the function modules and develops the middleware. All this make product tracking system more efficient.",
        "keywords": [
            "RFID middleware",
            "PCB assembly",
            "Radio Frequency Identification(RFID)"
        ],
        "authors": [
            {
                "name": "TIAN Shi-yong",
                "org": "Computer Integrated Manufacturing Research Institute,Shanghai Jiaotong University,Shanghai "
            },
            {
                "name": "WU Li-hui",
                "org": "Computer Integrated Manufacturing Research Institute,Shanghai Jiaotong University,Shanghai "
            },
            {
                "name": "SUN Lei",
                "org": "Computer Integrated Manufacturing Research Institute,Shanghai Jiaotong University,Shanghai "
            },
            {
                "name": "ZHANG Jie",
                "org": "Computer Integrated Manufacturing Research Institute,Shanghai Jiaotong University,Shanghai "
            }
        ],
        "venue": "Computer Engineering",
        "year": 2009
    },
    "2QColGrn": {
        "id": "2QColGrn",
        "title": "The Digital Image Scrambling Encryption and Its HDTV Application",
        "abstract": "This paper introduces the digital image scrambling encryption and its HDTV application.Firstly,the principle of digital image scrambling encryption and current methods are introduced in this paper.Secondly,this paper discusses a typical method based on the Gray code and demonstrates a Matlab program based on the Gray code.Finally,the HDTV application of the scrambling encryption is discussed.",
        "keywords": [
            "Self-synchronous scrambler",
            "Encryption",
            "Gray code transformation"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Institute of Intelligence Control,Automation Department,Shanghai Jiaotong University,Shanghai ,China"
            },
            {
                "name": "WANG Wei",
                "org": "Institute of Intelligence Control,Automation Department,Shanghai Jiaotong University,Shanghai ,China"
            }
        ],
        "venue": "Microcomputer Applications",
        "year": 2009
    },
    "KYMlFwsh": {
        "id": "KYMlFwsh",
        "title": "Modeling technology for semiconductor wafer fabrication system based on Agent-oriented knowledge colored timed Petri net",
        "abstract": "For effective modeling of large-scale complex Semiconductor Wafer Fabrication System (SWFS), an Agent-Oriented Knowledge Colored Timed Petri Net (AOKCTPN) modeling approach was proposed. In machine agent layer, system resources, internal behaviors and relevant knowledge were encapsulated to form the AOKCTPN-based machine Agent models. In machine group Agent layer and system Agent layer, the AOKCTPN-based models were configured according to the internal and external relationships among machine group Agents. Based on the AOKCTPN-based modeling technology, modeling complexity was reduced, re-configurability and reusability of model were improved, and decision-making ability of model was enhanced. An illustrative example of 150 mm SWFS in Shanghai demonstrated the effectiveness of the proposed approach.",
        "keywords": [
            "Agent",
            "Modeling",
            "Petri net",
            "Semiconductor wafer fabrication system"
        ],
        "authors": [
            {
                "name": "WU Li-hui",
                "org": "Shanghai Jiaotong University(Shanghai Jiaotong University,Shanghai Jiao Tong University,Shanghai Jiaotong Univ.),Shanghai,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Shanghai Jiaotong University(Shanghai Jiaotong University,Shanghai Jiao Tong University,Shanghai Jiaotong Univ.),Shanghai,China"
            }
        ],
        "venue": "Jisuanji Jicheng Zhizao Xitong/Computer Integrated Manufacturing Systems, CIMS",
        "year": 2009
    },
    "niZGR2Qi": {
        "id": "niZGR2Qi",
        "title": "The Research and Application of the Operation of Electrical Assembly Line Based On Hierarchical Optimization",
        "abstract": "Focusing on the features of assembly plant,distribute the job scheduling of assembly line into the plant management decision layer and the plant assemble unit operation layer,and establish an operation scheduling model based on the theory of hierarchical optimization.In this model,the upper layer is the plant management layer,in aim to keep the lowest controlling cost.The sub layer includes several parallel assemble unites.This layer will optimize the system based on the constraint of the equipment ability and resource distribution,in order to minimize the finishing time.Moreover,the essay also draws into Genetic Algorithm to solve the model,and prove the validity and feasibility of it.This method combat the problem of the balance use of cost and capability between the plant management layer and the plant layer,which achieve the automation and optimization of the scheduling of assemble operations.",
        "keywords": [
            "hierarchical optimization",
            "electrical assembly line",
            "genetic algorithm(GA)"
        ],
        "authors": [
            {
                "name": "CHEN Xue-fang",
                "org": "Mechanical and electronic Engineering Department,Suzhou Vocational University,Suzhou ,China"
            },
            {
                "name": "ZHU Qiong",
                "org": "School of Mechanical Engineering,Shanghai Jiaotong University,Shanghai ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "School of Mechanical Engineering,Shanghai Jiaotong University,Shanghai ,China"
            }
        ],
        "venue": "Modular Machine Tool & Automatic Manufacturing Technique",
        "year": 2009
    },
    "kGfNnz5z": {
        "id": "kGfNnz5z",
        "title": "Scheduling with Single AGV and Single Buffer Area for Flexible Production System",
        "abstract": "To deal with the flexible production system scheduling problem,a new scheduling model was proposed based on the constrains of the single AGV and single buffer area.The strategy of the AGV scheduling was illustrated and the math model with the combination of job scheduling and AGV scheduling was constructed. To solve this model,a modified genetic algorithm was proposed to improve the average machine efficiency by optimizing its gene order.The result of scheduling is not only the jobs processing sequence in every workstation,but the move path of AGV.The experiment results show better computational performance of the proposed algorithm.Equipment utilization is also improved under the same experiment conditions.",
        "keywords": [
            "Automatic guidance vehicle (AGV)",
            "Flexible production system",
            "Genetic algorithm",
            "Scheduling"
        ],
        "authors": [
            {
                "name": "DONG Yi-jun",
                "org": "School of Mechanical Engineering,Shanghai Jiaotong University,Shanghai ,China"
            },
            {
                "name": "ZHANG Gong",
                "org": "School of Mechanical Engineering,Shanghai Jiaotong University,Shanghai ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "School of Mechanical Engineering,Shanghai Jiaotong University,Shanghai ,China"
            }
        ],
        "venue": "Journal of Shanghai Jiaotong University",
        "year": 2010
    },
    "1KBKsj4K": {
        "id": "1KBKsj4K",
        "title": "An inventory model with dynamic emergency ordering under stochastic lead time",
        "abstract": "Under the stochastic lead time and uncertain demand in the inventory system, an emergency ordering policy to optimize inventory replenishment was studied. Based on the classic (Q, R) policy, the inventory model with real time information in the process of regular ordering was set up. By comparing different cycle expected cost with different choices, this paper gave the expressions to calculate the optimal emergency ordering point and order amount. The numerical analysis shows that the model proposed can save much cost and it also proves the rationality of the optimal solution and the influence of the cost of emergency order.",
        "keywords": [
            "Emergency ordering",
            "Inventory model",
            "Order progress information",
            "Stochastic lead time"
        ],
        "authors": [
            {
                "name": "Lei Sun",
                "org": "Shanghai Jiaotong University(Shanghai Jiaotong University,Shanghai Jiao Tong University,Shanghai Jiaotong Univ.),Shanghai,China"
            },
            {
                "name": "Qiong Zhu",
                "org": "Shanghai Jiaotong University(Shanghai Jiaotong University,Shanghai Jiao Tong University,Shanghai Jiaotong Univ.),Shanghai,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Shanghai Jiaotong University(Shanghai Jiaotong University,Shanghai Jiao Tong University,Shanghai Jiaotong Univ.),Shanghai,China"
            }
        ],
        "venue": "Shanghai Jiaotong Daxue Xuebao/Journal of Shanghai Jiaotong University",
        "year": 2010
    },
    "Q86tlDIK": {
        "id": "Q86tlDIK",
        "title": "A phase space reconstruction based approach to throughput prediction in semiconductor wafer fabrication system",
        "abstract": "In order to manage and control semiconductor wafer fabrication system (SWFS) more effectively, the daily throughput prediction data of wafer fab are often used in the planning and scheduling of SWFS. In this paper, an artificial neural network (ANN) prediction method based on phase space reconstruction (PSR) and ant colony optimization (ACO) is presented, in which the phase space reconstruction theory is used to reconstruct the daily throughput time series, the ANN is used to construct the daily throughput prediction model, and the ACO is used to train the connection weight and bias values of the neural network prediction model. Testing with factory operation data and comparing with the traditional method show that the proposed methodology is effective. Copyright © 2010 Editorial Department of Journal of Donghua University.",
        "keywords": [
            "Artificial neural network",
            "Daily throughput prediction",
            "Phase space reconstruction"
        ],
        "authors": [
            {
                "name": "WU Li-hui",
                "org": "Shanghai Jiaotong University(Shanghai Jiaotong University,Shanghai Jiao Tong University,Shanghai Jiaotong Univ.),Shanghai,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Shanghai Jiaotong University(Shanghai Jiaotong University,Shanghai Jiao Tong University,Shanghai Jiaotong Univ.),Shanghai,China"
            }
        ],
        "venue": "Journal of Donghua University (English Edition)",
        "year": 2010
    },
    "75Sehoa7": {
        "id": "75Sehoa7",
        "title": "An Order Decision and Production Planning Integrated Availableto-Promise Model for Multi-plant Manufacturing",
        "abstract": "By considering factors such as plant geographic position,production capacity,inventory restriction,transport capacity and customer satisfaction etc.,an order decision and production planning integrated ATP model was developed for assemble-to-order multi-plant manufacturer.Finally,a series of performance analysis experiment was conducted to reveal the impact of some key factors such as planning horizon,batch interval etc.on overall profit.",
        "keywords": [
            "mixed integer programming(MIP)",
            "production planning and scheduling",
            "available-to-promise(ATP)",
            "multi-plant"
        ],
        "authors": [
            {
                "name": "WANG Wen-hao",
                "org": "School of Mechanical Engineering,Shanghai Jiaotong University,Shanghai ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "School of Mechanical Engineering,Shanghai Jiaotong University,Shanghai ,China"
            }
        ],
        "venue": "Journal of Shanghai Jiaotong University",
        "year": 2011
    },
    "7cFhrva5": {
        "id": "7cFhrva5",
        "title": "Real-time Schedule Approach for Material Handling System of Wafer Fabrication",
        "abstract": "The promotion of efficiency of transporting system is significant to the Semiconductor Wafer Fabrication System(SWFS).To reduce the average traveling time,the average waiting time,and blockages in the Interbay system,this paper proposes a new real-time method using Hungarian algorithm.Simulation results based on data of 300 mm wafer fabrication systems show that this method outperforms the traditional schedule approaches in term of overall efficiency and performance of Interbay material handling system.",
        "keywords": [
            "Automatic Material Handling System(AMHS)",
            "wafer fabrication",
            "Hungarian algorithm"
        ],
        "authors": [
            {
                "name": "SUN Yin-bin",
                "org": "Institute of Computer Integrated Manufacturing,Shanghai Jiaotong University,Shanghai ,China"
            },
            {
                "name": "WU Li-hui",
                "org": "Institute of Computer Integrated Manufacturing,Shanghai Jiaotong University,Shanghai ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Institute of Computer Integrated Manufacturing,Shanghai Jiaotong University,Shanghai ,China"
            }
        ],
        "venue": "Computer Engineering",
        "year": 2011
    },
    "LBeCnH2T": {
        "id": "LBeCnH2T",
        "title": "An Available-to-Promise Model for Order Promising Based on Dynamic Resource Reservation Policy and Dynamic Pricing Policy",
        "abstract": "Facing uncertain future customer orders,a firm is challenged to make good order promising and fulfillment decisions that balance current critical resources and future customer demands.The combination of a dynamic resource reservation policy and a dynamic pricing policy for order-promising was proposed,based on which a corresponding stochastic model was developed.Assuming known independent demand distributions,the optimal reservation level and price level was derived and proved to maximize expected total profit.Finally,a series of simulation experiments was conducted to reveal the impact of initial availability and demand-pricing elasticity.",
        "keywords": [
            "pricing",
            "resource allocation",
            "available-to-promise(ATP)",
            "reservation policy",
            "order management"
        ],
        "authors": [
            {
                "name": "WANG Wen-hao",
                "org": "School of Mechanical Engineering,Shanghai Jiao Tong University,Shanghai ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "School of Mechanical Engineering,Shanghai Jiao Tong University,Shanghai ,China"
            }
        ],
        "venue": "Industrial Engineering and Management",
        "year": 2011
    },
    "14NYdqfg": {
        "id": "14NYdqfg",
        "title": "A Fuzzy Logic Decision-making Based on Wafer Lot's Transportation Cost Model for the Interbay Material Handling System",
        "abstract": "To obtain better complex schedule performances of the Interbay material handling system in 300mm semiconductor manufacturing systems(SMSs),a fuzzy logic decision-making based w afer lot's transportation cost model for the Interbay material handling system is proposed.With experimental data from an Interbay material handling system of 300mm SMSs,the proposed fuzzy logic decision-making based w afer lot's transportation cost model is compared w ith the traditional w afer lot's transportation cost model w ith constant w eight coefficients.The results demonstrate that the proposed w afer lot's transportation cost model has better comprehensive schedule performances of the Interbay material handling system and SMSs than the traditional w afer lot's transportation cost model.",
        "keywords": [
            "fuzzy logic",
            "wafer lot",
            "interbay material handling system",
            "transportation cost model"
        ],
        "authors": [
            {
                "name": "WU Li-hui",
                "org": "School of Mechanical & Electrical Engineering,Henan Univ.of Technology,Zhengzhou , China"
            },
            {
                "name": "YAN Bing-sheng",
                "org": "School of Mechanical & Electrical Engineering,Henan Univ.of Technology,Zhengzhou , China"
            },
            {
                "name": "ZHANG Jie",
                "org": "School of Mechanical Engineering,Shanghai Jiaotong Univ.,Shanghai ,China"
            }
        ],
        "venue": "Modular Machine Tool & Automatic Manufacturing Technique",
        "year": 2012
    },
    "uJozX1xZ": {
        "id": "uJozX1xZ",
        "title": "Design and Development of Embedded Adapter for Data Acquisition of CNC Machine Tools",
        "abstract": "The traditional data acquisition system for CNC machine tools is based on wired communication and only some types of data have been acquired,which is lack of mobility in communication and adaptability in data acquisition,so chosen wireless communication as communication channel between embedded adapters and the host computer,designed and developed embedded adapter for networking and data acquisition of CNC machine tools.Then designed hardware system of embedded adapter,selected and customized embedded operation system,developed data acquisition and processing software according to the requirements of communication and data acquisition.The test result shows that embedded adapters supports wireless communication with the host computer,realized data acquisition of CNC machine tools and heterogeneous data processing and improved the flexibility of system.",
        "keywords": [
            "wireless communication",
            "data acquisition",
            "embedded"
        ],
        "authors": [
            {
                "name": "XIA Zhi",
                "org": "School of Mechanical Engineering,Shanghai Jiao Tong University,Shanghai ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "School of Mechanical Engineering,Shanghai Jiao Tong University,Shanghai ,China"
            },
            {
                "name": "ZHANG Gong",
                "org": "School of Mechanical Engineering,Shanghai Jiao Tong University,Shanghai ,China"
            }
        ],
        "venue": "Modular Machine Tool & Automatic Manufacturing Technique",
        "year": 2012
    },
    "tHl7Cf3H": {
        "id": "tHl7Cf3H",
        "title": "A Scheduling Approach for Interbay System with Hybrid Intelligence",
        "abstract": "To obtain better multi-objective performances of the Interbay material handling system in wafer fabrication,a novel hybrid intelligence-based dispatching approach for the Interbay material handling system is proposed.The weight coefficients of wafer lots’ transportation cost model are adjusted adaptively by Takagi-Sugeno based fuzzy logic method.The optimized dispatching solution between wafer lots and transport vehicles is obtained based on Hungarian algorithm.Experimental results demonstrate that the proposed approach has better comprehensive performances of the Interbay material handling system and SMS than traditional dispatching approaches.",
        "keywords": [
            "fuzzy logic",
            "scheduling",
            "multi-objective",
            "Interbay system",
            "wafer fabrication",
            "Hungarian method"
        ],
        "authors": [
            {
                "name": "WU Li-hui",
                "org": "School of Mechanical and Electrical Engineering,Henan University of Technology,Zhengzhou ,China"
            },
            {
                "name": "YAN Bing-sheng",
                "org": "School of Mechanical and Electrical Engineering,Henan University of Technology,Zhengzhou ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "School of Mechanical Engineering,Shanghai Jiaotong University,Shanghai ,China"
            }
        ],
        "venue": "Computer Engineering",
        "year": 2012
    },
    "lCxuUoer": {
        "id": "lCxuUoer",
        "title": "Performance analysis modeling approach for wafer fabrication material handling system",
        "abstract": "To rapidly and effectively analyze the performances of Automated Material Handling System(AMHS)during the design phase,an Extended Markov Chain Model(EMCM)based modeling approach was proposed.The scale of AMHS's performance analytical model was reduced and the state space explosion phenomenon of the model was avoided.With production data from a 300mm semiconductor wafer fabrication line,the proposed modeling approach was compared with simulation analytical approach.The result showed that the 96% relative error value of performance indexes between EMCM and simulation model such as AMHS's movement,vehicle's utilization ratio and interval of vehicle's mean arrival time within the range of[-8%,10%].The analytical efficiency of EMCM was 600times higher than the simulation model.It demonstrated that the proposed EMCM based modeling approach was effective.",
        "keywords": [
            "Automated material handling system",
            "Extended Markov chain model",
            "Modeling",
            "Wafer fabrication"
        ],
        "authors": [
            {
                "name": "WU Li-hui",
                "org": "School of Mechanical & Electrical Engineering,Henan University of Technology,Zhengzhou ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "School of Mechanical Engineering,Shanghai Jiaotong University,Shanghai ,China"
            }
        ],
        "venue": "Computer Integrated Manufacturing Systems",
        "year": 2013
    },
    "4Efu2i2b": {
        "id": "4Efu2i2b",
        "title": "Analysis on the Game Theory of Building Dynamic Union by Railway Diversified Logistics Enterprises",
        "abstract": "Focusing on the problems and competition existing in railway diversified logistics enterprises,the essay analyzes the necessity of building dynamic union by using game theory.The essay carries out the benefit-cost analysis with game theory under the cooperation strategy of railway diversified logistics enterprises from angle of regional dimension,then gets ordinary game theory model and the expanded game theory model,and points out that railway diversified logistics enterprises shall enhance their competitive forces on the basis of maximum profits through their union and cooperation.",
        "keywords": [
            "dynamic union",
            "railway",
            "logistics enterprises",
            "game theory"
        ],
        "authors": [
            {
                "name": "YI Ming",
                "org": "School of Economics and Management,Southwest Jiaotong University,Chengdu,Sichuan ,China"
            },
            {
                "name": "ZHOU Guo-hua",
                "org": "School of Economics and Management,Southwest Jiaotong University,Chengdu,Sichuan ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "School of Economics and Management,Southwest Jiaotong University,Chengdu,Sichuan ,China"
            }
        ],
        "venue": "Railway Transport and Economy",
        "year": 2006
    },
    "RdQpmmXC": {
        "id": "RdQpmmXC",
        "title": "New method for ride quality analysis of vehicle",
        "abstract": "Current spectral analysis for evaluating the rail ride quality effectively is based on the sampling data at a uniform time interval, but the train is of fluctuation velocity in motion, which results in a non-uniform interval between consecutive sampling data. Therefore the accuracy of routine spectral analysis is in doubt when applying it in evaluating the rail ride quality. This paper presents a new way, namely, re-sampling with variable frequency to eliminate the influence of the train's uneven velocity. Its feature is that there is no need for precision measurement of the train's moving speed. Experiment results from the test-bed of rolling stock vibration show that it is valid.",
        "keywords": [
            "Non-uniform sample",
            "Rail ride quality",
            "Resample and reconstitute",
            "Signal processing"
        ],
        "authors": [
            {
                "name": "LIN Jian-hui",
                "org": "Southwest Jiaotong University(Southwest Jiaotong University,Southwest Jiaotong Univ.),Chengdu,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Southwest Jiaotong University(Southwest Jiaotong University,Southwest Jiaotong Univ.),Chengdu,China"
            },
            {
                "name": "Yan Gao",
                "org": "Chengdu Electromechanical College(Chengdu Electromechanical College),Chengdu,China"
            },
            {
                "name": "LI Tian-rui",
                "org": "Southwest Jiaotong University(Southwest Jiaotong University,Southwest Jiaotong Univ.),Chengdu,China"
            }
        ],
        "venue": "Journal of Donghua University (English Edition)",
        "year": 2006
    },
    "y5jTL4zl": {
        "id": "y5jTL4zl",
        "title": "Application of TMS320LF2407 in micro-robot control system",
        "abstract": "In this paper introduced the application of specially designed motor control chip TMS320LF2407 in micro-robot control system.Aiming at the poor flexibility and expansion of the robot system,in which using PIC micro-controller to set up,a new scheme of using the DSP chip TMS320LF2407 as CPU to set up micro-robot control system was proposed.This system could to control servos and stepper motor by using a single chip of DSP.The design is of simple structure,small the volume of the control system and better performance in controlling.It has increased system's flexibility by DSP chip's abundant peripheral hardware.",
        "keywords": [
            "Servos",
            "Control system",
            "DSP",
            "Stepper motor",
            "Micro-robot"
        ],
        "authors": [
            {
                "name": "JIANG Hai-ying",
                "org": "School of Mechanical Engineering,Southwest Jiaotong University,Chengdu ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "School of Mechanical Engineering,Southwest Jiaotong University,Chengdu ,China"
            }
        ],
        "venue": "China Measurement Technology",
        "year": 2007
    },
    "D55YGJ3L": {
        "id": "D55YGJ3L",
        "title": "Signal analysis of mechanical modulated velocity processes based on the fractional fourier transform",
        "abstract": "The mechanical modulated velocity processes was treated.The Fractional Fourier Transform(FRFT) was applied to find the super properties in time-frequency plane about the chirp signal.So it could eliminate the influence of the uneven rotating velocity on signal analysis.It is useful in signal analysis and system detection and fault diagnosis on mechanical modulated velocity processes.",
        "keywords": [
            "Chirp signal",
            "Modulated velocity processes",
            "Fractional fourier transform(FRFT)"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "School of Mechanical Engineering,Southwest Jiaotong University,Chengdu ,China"
            },
            {
                "name": "JIANG Hai-Ying",
                "org": "School of Mechanical Engineering,Southwest Jiaotong University,Chengdu ,China"
            },
            {
                "name": "LIN Jian-hui",
                "org": "National Traction Power Lab.,Southwest Jiaotong University,Chengdu ,China"
            }
        ],
        "venue": "China Measurement Technology",
        "year": 2007
    },
    "vFhaO2Ea": {
        "id": "vFhaO2Ea",
        "title": "State-of-the-art review and trend of studies on coupling vibration for vehicle and highway bridge system",
        "abstract": "With the increase of highway transportation and the development of long-span flexible bridges, both the dynamic responses of highway bridges under high-speed and heavy vehicles and the safety control of vehicles have deserved general concerns. Starting with early experimental studies and classical analysis theory, the present primary achievements are summarized roundly according to vehicle analytical model, bridge analytical model, surface roughness of road and numerical method. Finally, some existing problem on vehicle-bridge interaction at present is mentioned and the direction of the further research on vehicle-bridge interaction in the future is pointed out.",
        "keywords": [
            "Dynamic response",
            "Highway bridge",
            "Summarize",
            "Surface roughness of road",
            "Vehicle-bridge interaction"
        ],
        "authors": [
            {
                "name": "LI Xiao-zhen",
                "org": "Southwest Jiaotong University(Southwest Jiaotong University,Southwest Jiaotong Univ.),Chengdu,China"
            },
            {
                "name": "ZHANG Li-ming",
                "org": "Southwest Jiaotong University(Southwest Jiaotong University,Southwest Jiaotong Univ.),Chengdu,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Southwest Jiaotong University(Southwest Jiaotong University,Southwest Jiaotong Univ.),Chengdu,China"
            }
        ],
        "venue": "Gongcheng Lixue/Engineering Mechanics",
        "year": 2008
    },
    "Mw2087kl": {
        "id": "Mw2087kl",
        "title": "Location control system design with wireless microcontroller NRF24E1",
        "abstract": "One wireless location control system was research and prepared with the wireless MCU NRF24E1 embedded compatible microcontroller 8051,approach switch sensor and SSR,the design plan of the hardware and software for this control system was described,and this system realized the function of warning as object approach and cutting off the power supply.It also was used in the location control of crash successfully.The application proved that the system is of advantages such as easy operation,stable,well performance in control with flexibility.The above prospected its good applications.",
        "keywords": [
            "NRF24E1",
            "Location control",
            "Wireless sensor",
            "SSR",
            "Approach switch"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "School of Mechanical Engineering,Southwest Jiaotong University,Chengdu ,China"
            }
        ],
        "venue": "China Measurement & Testing Technology",
        "year": 2008
    },
    "b7GY1AK0": {
        "id": "b7GY1AK0",
        "title": "Design of intelligent monitor and control system for overhead and gantry crane",
        "abstract": "Intelligent monitor and control system for overhead and gantry crane,which was based by AT89C5131,could real-time measure the job parameter and register at the same time.The job parameter was included the moving parts of the crane and dip angle of the tilting cable.The data of operation error could be transmitted to the computer through the USB interface,consulted the printing for the administrative personnel.The application proves that the system is of advantages such as easy operation,convenient assemblage,stable,anti-jamming.The use of the system can effectively avoid the scene of the brutal damage to the operating cranes.This system which had the far-reaching scientific management will be widely applied.",
        "keywords": [
            "Overhead and gantry crane",
            "Instrumentation and automation devices",
            "Location control",
            "USB interface",
            "AT89C5131"
        ],
        "authors": [
            {
                "name": "XU Qian",
                "org": "School of Mechanical Engineering,Southwest Jiaotong University,Chengdu ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "School of Mechanical Engineering,Southwest Jiaotong University,Chengdu ,China"
            },
            {
                "name": "WEN Bi",
                "org": "School of Mechanical Engineering,Southwest Jiaotong University,Chengdu ,China"
            }
        ],
        "venue": "China Measurement & Test",
        "year": 2009
    },
    "V59MjlfZ": {
        "id": "V59MjlfZ",
        "title": "Wireless data acquisition system based on NRF24E1 and FPGA technology",
        "abstract": "In order to solve the problem of state control for precision instruments and safety monitoring of bridges,radio frequency technology and FPGA technology were used to develop a wireless data acquisition system.Compared with the transmission cable,using wireless single chip nRF24E1 to achieve a wireless communications fupctions avoid the signal transmission lines restrictions at operating site.FPGA device EP1C3T144C6 was use to achieve a data acquisition,which is much better than traditional single-chip control data acquisition system.The results show that this system is simple,stable and reliable,fast and efficient and will be widely applied.",
        "keywords": [
            "Radio-frequency",
            "nRF24E1",
            "Wireless communications",
            "Data acquisition",
            "FPGA"
        ],
        "authors": [
            {
                "name": "WEN Bi",
                "org": "School of Mechanical Engineering,Southwest Jiaotong University,Chengdu ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "School of Mechanical Engineering,Southwest Jiaotong University,Chengdu ,China"
            },
            {
                "name": "XU Qian",
                "org": "School of Mechanical Engineering,Southwest Jiaotong University,Chengdu ,China"
            }
        ],
        "venue": "China Measurement & Test",
        "year": 2009
    },
    "E6tM8TxE": {
        "id": "E6tM8TxE",
        "title": "Design of wireless data acquisition system based on USB interface",
        "abstract": "In recent years,the short distance wireless communication technology based on the wireless system-on-chip(SoC) has been developed rapidly.The function of wireless data acquisition and communication,which was remotely controlled by PC,can be realized through combining wireless sensor technology with USB technology and using the wireless MCU NRF24E1 with embedded 8051 compatible microcontroller,AVR MCU and wireless data acquisition system of Philips PDIUSB12 with USB interface.The software designs of this system were composed of programs of wireless communication,MCU firmware,PC device driver and application.The application results proved that this system is of advantages such as easy to operate,reliable and stable.Thus it has a broad application prospect.",
        "keywords": [
            "USB",
            "NRF24E1",
            "AVR MCU",
            "PDIUSB12",
            "Data acquisition"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "School of Mechanical Engineering,Southwest Jiaotong University,Chengdu ,China"
            }
        ],
        "venue": "China Measurement & Test",
        "year": 2009
    },
    "Qfb2uxLg": {
        "id": "Qfb2uxLg",
        "title": "Linewidth Measurement of Narrow Fiber Laser Based on the DSHI",
        "abstract": "As an important parameter of the coherent optical system,the linewidth of narrow fiber laser must be measured accurately.Compared with other currently available linewidth measurement techniques,the Delayed Self-heterodyne Interferometer(DSHI) technique is the most promising one.In this paper,theory of the DSHI for determining the linewidth of lasers is described in detail.The MATLAB emulator is programmed to analyze the effects of fiber delay line on the results.Furthermore,an experimental setup based on the DSHI is constructed to measure IPG's fiber laser linewidth.We substitute oscilloscope for the spectrum analyzer in this system,and the software algorithm is designed for the analysis of the photocurrent signal.From numerical analysis,the measured linewidth of the IPG's fiber laser is about 16 kHz,which is in the range of an ideal accuracy.",
        "keywords": [
            "fiber delay line",
            "linewidth measurement",
            "DSHI",
            "fiber laser"
        ],
        "authors": [
            {
                "name": "XIAO Hua-ju",
                "org": "National Key Laboratory of Shock Wave and Detonation Physics,Institute of Fluid Physics,Chinese Academy of Engineering Physics,Mianyang ,Sichuan Province,China;Department of Mechanical Engineering,Southwest Jiaotong University,Chengdu ,China"
            },
            {
                "name": "WANG Xiang",
                "org": "National Key Laboratory of Shock Wave and Detonation Physics,Institute of Fluid Physics,Chinese Academy of Engineering Physics,Mianyang ,Sichuan Province,China"
            },
            {
                "name": "MA Yun",
                "org": "National Key Laboratory of Shock Wave and Detonation Physics,Institute of Fluid Physics,Chinese Academy of Engineering Physics,Mianyang ,Sichuan Province,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Mechanical Engineering,Southwest Jiaotong University,Chengdu ,China"
            }
        ],
        "venue": "Opto-Electronic Engineering",
        "year": 2010
    },
    "uLJ9A4tG": {
        "id": "uLJ9A4tG",
        "title": "Nonuniformly sampled signal analysis for track irregularity",
        "abstract": "Current spectral analysis for track irregularity is based on sampling data in uniform intervals, but a train has fluctuating velocity, therefore, the accuracy of the traditional spectral analysis is in doubt. A nonuniformly sampled sequence was studied to set up the power spectral density(PSD) formula of an nonuniformly sampled signal. The new formula was used to analyze the nonuniformly sampled cases when the sampling interval was Gaussian distribution. The results showed that the PSD formula of a nonuniformly sampled signal includes the classic uniformly sampled signal's PSD formula, it verifies the accuracy of the new formula. Finally a method was put forward to measure the probability density function of the sampling interval for track irregularity spectral analysis.",
        "keywords": [
            "Nonuniformly sampling",
            "Power spectral density",
            "Probability density function",
            "Random process",
            "Track irregularity"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Southwest Jiaotong University(Southwest Jiaotong University,Southwest Jiaotong Univ.),Chengdu,China"
            },
            {
                "name": "LIN Jian-hui",
                "org": "Southwest Jiaotong University(Southwest Jiaotong University,Southwest Jiaotong Univ.),Chengdu,China"
            }
        ],
        "venue": "Zhendong yu Chongji/Journal of Vibration and Shock",
        "year": 2011
    },
    "tINdcLW3": {
        "id": "tINdcLW3",
        "title": "Study of Performance-based Fire Resistance Design Methodology for High Speed Train",
        "abstract": "The fire safety design of the high speed train was met by a challenge from the using of enormous polymer materials and the sealed cabin.A new methodology of performance-based fire resistance design for high speed train was studied.The overall fire safety can be qualitatively and quantitatively assessed by analysis software of the fire simulation and the evacuating simulation.Based on the fire test,the certain performance of the materials in a cabin and the total combustible of the train could be illustrated.The results can serve as a good reference for the fire safety design of the high speed trains.",
        "keywords": [
            "fire test",
            "performance-based fire resistance",
            "fire safety design",
            "high speed train",
            "fire simulation"
        ],
        "authors": [
            {
                "name": "LIANG Jun-hai",
                "org": "CRS Qingdao Sifang Locomotive and Rolling Stock Co.,Qingdao ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "School of Mechanical Engineering,Southwest Jiaotong University,ChengDu ,China"
            },
            {
                "name": "LIN Jian-hui",
                "org": "National Traction Power Laboratory,Southwest Jiaotong University,ChengDu ,China"
            },
            {
                "name": "LIU Lu",
                "org": "National Traction Power Laboratory,Southwest Jiaotong University,ChengDu ,China"
            },
            {
                "name": "ZHANG Bing",
                "org": "National Traction Power Laboratory,Southwest Jiaotong University,ChengDu ,China"
            }
        ],
        "venue": "Railway Energy Saving & Environmental Protection & Occupational Safety and Health",
        "year": 2012
    },
    "3SydZh9i": {
        "id": "3SydZh9i",
        "title": "Wear properties of sub-micrometer SiCp/Al composites",
        "abstract": "Sliding wear-resistance of 1.5-5.0% SiCp(130 nm)/Al(149-75 μm) matrix composites fabricated by powder metallurgy followed by hot extrusion has been investigated. The purpose is to study the submicrometer SiCp dispersed in alumina matrix. The results showed that 1.5% and 5.0% of SiCp/Al composite have excellent sliding wear resistance. With the increase in SiCp (130 nm) volume fraction, the sliding wear property increases, and the sliding wear resistance is respectively 1.21 and 4.00 times of popularly used 6.5-0.4 bronze bearing materials, and 1.10 and 3.66 times of Al under the higher load. An excellent wear-resistance microstructure consisting of aluminum matrix, minute hole, spherical and moderate size, and homogeneous distribution of SiCp was formed in the wear surface of SiCp/Al matrix composites due to the plastic deformation resulting from friction and attrition.",
        "keywords": [
            "Friction and wear property",
            "Material fabrication",
            "Pressure property",
            "Sub-micrometer SiCp/Al composites"
        ],
        "authors": [
            {
                "name": "GE Xiao-lan",
                "org": "Jiangsu University(Jiangsu University),Zhenjiang,China"
            },
            {
                "name": "XU Xiao-jing",
                "org": "Jiangsu University(Jiangsu University),Zhenjiang,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Jiangsu University(Jiangsu University),Zhenjiang,China"
            },
            {
                "name": "JU Zhi-lan",
                "org": "Jiangsu University(Jiangsu University),Zhenjiang,China"
            }
        ],
        "venue": "Jiangsu Daxue Xuebao (Ziran Kexue Ban) / Journal of Jiangsu University (Natural Science Edition)",
        "year": 2006
    },
    "NKWaM0il": {
        "id": "NKWaM0il",
        "title": "Wear behaviour of submicrometer SiCp reinforced Al matrix composite",
        "abstract": "The pressure properties,Vickers hardness and sliding wear-resistance of 1.5～5vol% SiC_P(130nm)/Al(149～75μm)matrix composites fabricated by powder metallurgy and hot extrusion were investigated to research the effect of submicrometer SiC_P dispersed in alumina matrix on the wear behaviour.The results show that increase in the volume fraction of SiC_P causes Vickers hardness increasing.Its Vickers hardness is 28.4 and 33.3 when the(volume) fraction of SiC_P(130nm) is 1.5～5vol%.The pressure properties of the material are 170MPa and 186MPa(respectively).Under the higher load,the sliding wear-property increases with increasing the volume fraction of SiC_P;1.5vol% and 5vol% SiC_P/Al composites have higher sliding wear-behavior than 6.5-0.4 bronze bearing material and Al.An excellent wear-resistance microstructure consisting of aluminum matrix and minute hole and homogeneous distribution SiC_P is formed in the wear surface of SiC_P/Al matrix composites.",
        "keywords": [
            "Friction and wear property",
            "Material fabrication",
            "Pressure property",
            "Submicrometer SiCp/Al composites"
        ],
        "authors": [
            {
                "name": "Xiaolan Ge",
                "org": "Jiangsu University(Jiangsu University),Zhenjiang,China"
            },
            {
                "name": "Xiaojing Xu",
                "org": "Jiangsu University(Jiangsu University),Zhenjiang,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Jiangsu University(Jiangsu University),Zhenjiang,China"
            }
        ],
        "venue": "Fuhe Cailiao Xuebao/Acta Materiae Compositae Sinica",
        "year": 2006
    },
    "Ls4fX2vG": {
        "id": "Ls4fX2vG",
        "title": "Vacuum brazing of SiC_p/Cu composite",
        "abstract": "Vacuum brazing of SiCp/Cu composite fabricated by powder metallurgy and followed by hot extrusion was carried out with Ti and AgCuTi brazing filler metal in different condition.The morphologies of joint shear fracture and shear strength were also investigated by means of scanning electron microscope and shearing test.The results showed that the bonding of SiCp/Cu composite performed with Ti filler is better than that with AgCuTi.The maximum shear strength of the joint brazed at 850 ℃ for 20 min is up to 70.5 MPa.When the volume fraction of SiCp increases,the shear strength of the joint decreases,and when the volume fraction of SiCp is more than 10 vol.%,the shear strength of the joint decreases more quickly.",
        "keywords": [
            "bonding strength",
            "SiCp/Cu composite",
            "vacuum brazing"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Mechanical Engineering Department,Jiangsu University,Zhenjiang ,Jiangsu,China"
            },
            {
                "name": "XU Xiaojing",
                "org": "Mechanical Engineering Department,Jiangsu University,Zhenjiang ,Jiangsu,China"
            },
            {
                "name": "DAI Fengze",
                "org": "Mechanical Engineering Department,Jiangsu University,Zhenjiang ,Jiangsu,China"
            }
        ],
        "venue": "Transactions of the China Welding Institution",
        "year": 2007
    },
    "DSCvIC9K": {
        "id": "DSCvIC9K",
        "title": "Effect of adding graphite on wear resistance of submicrometer SiCp/Cu composite",
        "abstract": "The effect of adding graphite on mechanical properties and sliding wear behavior of the Cu-matrix SiCp composite fabricated by cold pressing sintering and hot extrusion, using submicrometer SiCp, graphite and Cu powder as the raw material were investigated. The results show that adding graphite slightly decreases elongation, hardness, tightness and wear resistance, increase ultimate tensile strength to some extent. In addition the adherence on the wear surface, plasticity deformation and transfer tendency decrease remarkably, bringing about good antifriction function.",
        "keywords": [
            "Graphite",
            "Submicrometer SiCp/Cu composites",
            "Wear resistance"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Jiangsu University(Jiangsu University),Zhenjiang,China"
            },
            {
                "name": "XU Xiao-jing",
                "org": "Jiangsu University(Jiangsu University),Zhenjiang,China"
            },
            {
                "name": "DAI Feng-ze",
                "org": "Jiangsu University(Jiangsu University),Zhenjiang,China"
            }
        ],
        "venue": "Jinshu Rechuli/Heat Treatment of Metals",
        "year": 2007
    },
    "Lu2kQHzV": {
        "id": "Lu2kQHzV",
        "title": "Mechanical properties of micrometer and sub-micrometer SiCp reinforced Al matrix composites",
        "abstract": "The tensile and pressure properties of sub-micro and micrometer SiCp reinforced Al matrix composites were investigated to study the effect of SiCp in different scale on the mechanical properties. The results show that SiCp/Al matrix composites exhibit excellent plasticity, and elongation percentage descends with the increase of the volume fraction of SiCp. Its tensile and compressive strength increase with the augment of the volume fraction. The tensile strength and compressive strength of sub micrometer SiCp/Al are better than those of micrometer SiCp/Al. The rupture mechanism of sub micrometer SiCp/Al is that the vacancy zone forms at interface of SiCp/Al and expands in the substrate. The rupture mechanism of micrometer SiCp/Al is the cleavage fracture of SiCp and its expanding in the substrate.",
        "keywords": [
            "Composites materials",
            "Compressive strength",
            "Micrometer",
            "Sub-micrometer",
            "Tensile strength"
        ],
        "authors": [
            {
                "name": "GE Xiao-lan",
                "org": "Jiangsu University(Jiangsu University),Zhenjiang,China"
            },
            {
                "name": "Lan Cai",
                "org": "Jiangsu University(Jiangsu University),Zhenjiang,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Jiangsu University(Jiangsu University),Zhenjiang,China"
            },
            {
                "name": "LI Xin-cheng",
                "org": "Jiangsu University(Jiangsu University),Zhenjiang,China"
            }
        ],
        "venue": "Jiangsu Daxue Xuebao (Ziran Kexue Ban) / Journal of Jiangsu University (Natural Science Edition)",
        "year": 2008
    },
    "JYUYNKeO": {
        "id": "JYUYNKeO",
        "title": "Influence of laser shock processing on properties of SiCp/Cu composite weld crack restored by electro-spark overlaying",
        "abstract": "The crack of SiCp/Cu composite weld restored by electro-spark overlaying was processed by Nd: glass laser, and effects of laser shock processing on the electro-spark overlaying weld crack were analyzed. Surface welding residual stress distribution alone the transverse direction of the weld was investigated by X-ray diffraction techniques, the tensile strength of the weld was investigated by strength test, and the micro-hardness distribution of the weld surface was measured with a micro-hardness tester. The results show that when laser power is 35 J and laser spot diameter is 5 mm, the laser shock processing can reduce the welding residual stresses, which even change from the tensile stress into compressive stress, and improve the tensile strength and the hardness of SiCp/Cu composite weld restored by electro-spark overlaying.",
        "keywords": [
            "Electro-spark overlaying",
            "Laser shock processing",
            "Residual stress"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Jiangsu University(Jiangsu University),Zhenjiang,China"
            },
            {
                "name": "Le Zhu",
                "org": "Jiangsu University(Jiangsu University),Zhenjiang,China"
            },
            {
                "name": "Aihua Sun",
                "org": "Jiangsu University(Jiangsu University),Zhenjiang,China"
            },
            {
                "name": "Xiang Gu",
                "org": "Jiangsu University(Jiangsu University),Zhenjiang,China"
            }
        ],
        "venue": "Hanjie Xuebao/Transactions of the China Welding Institution",
        "year": 2009
    },
    "YkcfJnZc": {
        "id": "YkcfJnZc",
        "title": "Process optimization of investment casting of high pressure water pump housing based on ProCast software",
        "abstract": "Process optimization of investment casting of high pressure water pump housing made from ZL101A was conducted by the ProCast software. Shrinkage and dispersed shrinkage can easily occur in the root of the inlet pipe where the thick-wall position of the pump housing is and hot tearing can easily occur in the flange used to connect with the cover by observing temperature and stress field in filling and solidification process. Qualified castings can be obtained by reducing pouring temperature, increasing pre-heating temperature of the mould and adding heat preservation material to the pouring system. The yield of the pump housing has been substantially increased through the above measures.",
        "keywords": [
            "Investment casting",
            "ProCast",
            "Process optimization",
            "Water pump housing"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Jiangsu University(Jiangsu University),Zhenjiang,China"
            },
            {
                "name": "Gang Wang",
                "org": "Jiangsu University(Jiangsu University),Zhenjiang,China"
            },
            {
                "name": "ZHENG Fu-sheng",
                "org": "Guangdong Technical College of Water Resources and Electric Engineering(Guangdong Technical College of Water Resources and Electric Engineering),Guangzhou,China"
            },
            {
                "name": "Feng Li",
                "org": "Jiangsu University(Jiangsu University),Zhenjiang,China"
            },
            {
                "name": "DAI Peng-long",
                "org": "Jiangsu University(Jiangsu University),Zhenjiang,China"
            }
        ],
        "venue": "Zhuzao/Foundry",
        "year": 2012
    },
    "Gg22pxaj": {
        "id": "Gg22pxaj",
        "title": "Investment Casting of Aeronautical Parts with A356/TiB_2 Aluminum Matrix Composite",
        "abstract": "The relationship between the thermal-physical parameters of TiB2/A356 aluminum matrix composite and the volume fraction of TiB2 was investigated.Based on the secondary development of ProCAST software,the relationship between temperature change and thermal-physical parameters of TiB2/A356Al aluminum matrix composite with varied volumetric fraction of TiB2 was presented.A investment casting aeronautical part was simulated and produced.The results reveal that through increasing the pouring temperature and velocity of alloy melt as well as adding insulation materials around the shell mold,shrinkage porosity and shrinkage hole in the surface of the parts can be eliminated effectively.",
        "keywords": [
            "Investment Casting",
            "Aluminum Matrix Composite",
            "Numerical Simulation",
            "Casting Defect"
        ],
        "authors": [
            {
                "name": "Zhang Jie",
                "org": "School of Mechanical Engineering,Jiangsu University"
            },
            {
                "name": "Zhang Dongqi",
                "org": "School of Mechanical Engineering,Jiangsu University"
            },
            {
                "name": "Wu Pengwei",
                "org": "School of Mechanical Engineering,Jiangsu University"
            },
            {
                "name": "Wang Gang",
                "org": "School of Mechanical Engineering,Jiangsu University"
            }
        ],
        "venue": "Special Casting & Nonferrous Alloys",
        "year": 2012
    },
    "lfU8zX4u": {
        "id": "lfU8zX4u",
        "title": "The Review of Multi-Perspective Study on Factors in the Process of R&D and Innovation",
        "abstract": "The study of factors in the process of R&D and innovation is of great significance for the development of national knowledge economy and to achieve our strategic goal of building an innovation-oriented country.This paper conducts deep analysis and discussions on a number of factors affecting the process of domestic and foreign R&D and innovations,and summarizes the effect of internal factors,external factors and the vertical impacts,major research achievements and inadequate research.At last,the paper concludes the direction of further research in the field of study on factors affecting the R&D and innovation process.",
        "keywords": [
            "Effect Factors",
            "R&D",
            "Innovations"
        ],
        "authors": [
            {
                "name": "Zhang Jie",
                "org": "School of Management,Xi'an Jiaotong University,Xi'an ,China;Humanities and Foreign Language School,Xi'an University of Technology,Xi'an ,China"
            },
            {
                "name": "Cai Hong",
                "org": "School of Management,Xi'an Jiaotong University,Xi'an ,China"
            },
            {
                "name": "Zhao Jiaohui",
                "org": "School of Management,Xi'an Jiaotong University,Xi'an ,China"
            }
        ],
        "venue": "Science & Technology Progress and Policy",
        "year": 2011
    },
    "MscRdbjc": {
        "id": "MscRdbjc",
        "title": "Experimental research on medical wastewater disposal by supercritical water oxidation",
        "abstract": "The oxidation of medical wastewater in supercritical water was investigated experimentally in a batch reactor. The results show that the COD removal rate of medical wastewater obviously increases with the increases of reaction time and temperature rise; whereas it scarcely changes with pressure in the range of 25-27 MPa. Both MnSO4 and CuSO4 are active catalysts for COD removal rate of the wastewater, and CuSO4 offers greater influence when reaction time is less than 7 min. Ammonia-nitrogen mass concentration has no evident variation under various reaction conditions. The experimental data under the conditions of 420-480°C, 25 MPa, and oxidant stoichiometric ratio 300% were used to fit the rate of reaction in a non-linear regression analysis, with the parameter values determined as follows: activation energy (170.025±11.692)kJ/mol, pre-exponential factor (4.98±0.01)×108 min-1·mg-0.918·L0.918 and reaction order of wastewater (based on COD) 1.918±0.256, and the confidence level of such kinetics modeling is 93%. Based on the enthalpy changes of the reaction mediums, the reaction heat of the medical wastewater in supercritical water oxidation (SCWO) was studied. The results indicate that the reaction heat is 296.63 kJ/kg when the organics are completely oxidized.",
        "keywords": [
            "Catalyst",
            "Kinetics",
            "Medical wastewater",
            "Reaction heat consumption",
            "Supercritical water oxidation"
        ],
        "authors": [
            {
                "name": "Lu Zhou",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "WANG Shu-zhong",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "MA Hong-he",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "GONG Yan-meng",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "XU Dong-hai",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            }
        ],
        "venue": "Huaxue Gongcheng/Chemical Engineering (China)",
        "year": 2011
    },
    "RfJ8oeKj": {
        "id": "RfJ8oeKj",
        "title": "Experimental study on supercritical water oxidation of azo dye wastewater",
        "abstract": "For exploring the transformation mechanism of azo group during the oxidation reaction, the supercritical water oxidation of the azo dye C.I. Reactive Orange 7 was investigated in a batch reactor. Temperature, oxidant coefficient, initial COD mass concentration, reaction time and solution pH value were selected as process parameters and the total nitrogen removal rate and ammonia-nitrogen mass concentration as the responses. Central Composite Design (CCD)method was employed for the experimental design, of which an experimental matrix of five-factorial, five-level CCD consisting of 22 experimental runs was obtained. The experimental results were simulated and analyzed by response surface methodology. A quadratic polynomial equation was established for describing the relationship between the total nitrogen removal rate and five process parameters. The analysis of individual and interactive effects of the five variables on responses was conducted in accordance with the simulated equation. The experimental results demonstrate that during the supercritical water oxidation for C.I. Reactive Orange 7, total nitrogen degrades obviously, which can reach 20.10%-64.16%, but NH3-N mass concentration is rarely produced. Moreover, the five variables all made a positive one-order contribution on total nitrogen removal rate.",
        "keywords": [
            "Azo dye",
            "Response surface methodology",
            "Supercritical water oxidation",
            "Wastewater"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "WANG Shu-zhong",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Yang Guo",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "XU Dong-hai",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "GONG Yan-meng",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "TANG Xing-ying",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "WANG Yu-zhen",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            }
        ],
        "venue": "Huaxue Gongcheng/Chemical Engineering (China)",
        "year": 2011
    },
    "EENNggQS": {
        "id": "EENNggQS",
        "title": "TREATMENT OF WASTEWATER FROM PRODUCTION OF ETHOFENPROX BY SUPERCRITICAL WATER OXIDATION",
        "abstract": "An experimental study on ethofenprox manufacturing wastewater treatment by supercritical water oxidation was conducted in a batch reaction plant.The results of experiments show that the determined reaction conditions are 430 ℃,25 MPa,residence time of 5min and oxidation coefficient of 2.0.Under this condition,the order of oxidation abilities of H2O2,O2 and air as oxidants is H2O2>O2>air.SCWO pilot scale plant with the largest treatment capacity in China was used to treat ethofenprox manufacturing wastewater preliminarily.The indexes of COD,TOC,chromaticity and pH of reactor effluent can meet the first order of \"Integrated Wastewater Discharge Standard\"(GB 8978—1996).",
        "keywords": [
            "oxidant",
            "ethofenprox",
            "supercritical water oxidation",
            "pilot scale plant"
        ],
        "authors": [
            {
                "name": "Tang Xingying",
                "org": "School of Energy and Power Engineering,Xi′an Jiaotong University,Xi′an ,China"
            },
            {
                "name": "Wang Shuzhong",
                "org": "School of Energy and Power Engineering,Xi′an Jiaotong University,Xi′an ,China"
            },
            {
                "name": "Zhang Jie",
                "org": "School of Energy and Power Engineering,Xi′an Jiaotong University,Xi′an ,China"
            },
            {
                "name": "Xu Donghai",
                "org": "School of Energy and Power Engineering,Xi′an Jiaotong University,Xi′an ,China"
            }
        ],
        "venue": "Environmental Engineering",
        "year": 2012
    },
    "5vMN2Y1w": {
        "id": "5vMN2Y1w",
        "title": "Quantitative Analysis on Influence Factors of Technology Spillovers from Japan to China",
        "abstract": "Based on the basic characteristics of the technology spillover from Japan to China,this paper identifies seven key influence factors and establishes the measurement model of the factors.The empirical result shows the investment from Japan to China contributes most to the effects of technology spillover,which is followed by China's telecommunication basis and the Japanese patents granted in China.",
        "keywords": [
            "technology spillovers",
            "influence factors",
            "international trade"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "School of Management,Xi'an Jiaotong University,Xi'an ;School of Humanities and Foreign Languages,Xi'an University of Technology,Xi'an "
            },
            {
                "name": "CAI Hong",
                "org": "School of Management,Xi'an Jiaotong University,Xi'an "
            },
            {
                "name": "JIANG Zhan-kun",
                "org": "School of Management,Xi'an Jiaotong University,Xi'an "
            }
        ],
        "venue": "Soft Science",
        "year": 2012
    },
    "q7V0bvHW": {
        "id": "q7V0bvHW",
        "title": "Technology Spillover from Japan and Its Impact on R&D Stock & Economic Growth of China",
        "abstract": "Firstly technology knowledge stock absorbed by China from Japan via three channels : international trade , FDI and disembodied spillovers are calculated ; then the stock up with R&D stock accumulated by R&D and technology import to obtain total technology knowledge stock of China are summed ; finally the output elasticity coefficient and the rate of marginal revenue are calculated by applying the Generalized Cobb Douglas production function.Empirical testing indicates that the technology spillover effect from Japan to China is significant , and that this effect plays an important role in improving the amount of technology knowledge stock and economic growth of China.",
        "keywords": [
            "FDI",
            "Economic Growth",
            "Technology Spillover",
            "R&D Stock"
        ],
        "authors": [
            {
                "name": "Zhang Jie",
                "org": "Faculty of Humanities and Foreign Languages , Xi'an University of Technology , Xi'an  , China"
            },
            {
                "name": "Cai Hong",
                "org": "School of Management , Xi'an Jiaotong University"
            },
            {
                "name": "Jia Yujian",
                "org": "The Institute of Science & Technology Management and Policy , Xi'an Jiaotong University , Xi'an  , China"
            }
        ],
        "venue": "Science & Technology Progress and Policy",
        "year": 2012
    },
    "6z3xokvE": {
        "id": "6z3xokvE",
        "title": "The least square pre‐stack depth migration method on complex media",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "zhenchun li",
                "org": ""
            },
            {
                "name": "jianping huang",
                "org": ""
            },
            {
                "name": "huimin hao",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "yujin liu",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2011
    },
    "8Hd49Li0": {
        "id": "8Hd49Li0",
        "title": "Pre‐stack stochastic inversion theory and its application in L gas field of South China Sea",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "huimin hao",
                "org": ""
            },
            {
                "name": "ma guangke",
                "org": ""
            },
            {
                "name": "zhou jiaxiong",
                "org": ""
            },
            {
                "name": "sun yuecheng",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2011
    },
    "1c4iuRvV": {
        "id": "1c4iuRvV",
        "title": "From rock physics to glass earth—Tools for unconventional hydrocarbon reservoir exploring and developing",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "yu wenhui",
                "org": ""
            },
            {
                "name": "zhu wei",
                "org": ""
            },
            {
                "name": "huimin hao",
                "org": ""
            },
            {
                "name": "bian aifei",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2011
    },
    "aGrFmtMC": {
        "id": "aGrFmtMC",
        "title": "Potential sequence stratigraphic controls on frac design: An integrated 3‐D seismic reservoir characterization using P‐Wave impedance inversion data from Marcellus Shale, Pennsylvania",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "ilgar azizov",
                "org": ""
            },
            {
                "name": "j d morris",
                "org": ""
            },
            {
                "name": "arthur cheng",
                "org": ""
            },
            {
                "name": "uwe strecker",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "huimin hao",
                "org": ""
            },
            {
                "name": "stephen john singleton",
                "org": ""
            },
            {
                "name": "m smith",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2011
    },
    "vGUHVk4X": {
        "id": "vGUHVk4X",
        "title": "Geophysical interpretation techniques for petroleum‐rich depression and application effects",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "huimin hao",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "yiping xia",
                "org": ""
            },
            {
                "name": "ligui xu",
                "org": ""
            },
            {
                "name": "lianghe zheng",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2011
    },
    "p1J4ediD": {
        "id": "p1J4ediD",
        "title": "Compensation for attenuation based on nonstationary trace model",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "huimin hao",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "chen zengbao",
                "org": ""
            },
            {
                "name": "chen xiaohong",
                "org": ""
            },
            {
                "name": "l i jingye",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2011
    },
    "AM3KGdjo": {
        "id": "AM3KGdjo",
        "title": "Improved numerical simulation of seismic wave propagation in viscoelastic medium by one‐way equation",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "huimin hao",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "h e binghong",
                "org": ""
            },
            {
                "name": "w guochen",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2011
    },
    "0lqPfKcM": {
        "id": "0lqPfKcM",
        "title": "A gas detection factor of tight sandstones and its application",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "zhang jinqiang",
                "org": ""
            },
            {
                "name": "huimin hao",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "li chengcheng",
                "org": ""
            },
            {
                "name": "ma zhonggao",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2011
    },
    "iUhrdwjD": {
        "id": "iUhrdwjD",
        "title": "A spectral method for reflectivity estimate",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "huimin hao",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "rui guo",
                "org": ""
            },
            {
                "name": "shangxu wang",
                "org": ""
            },
            {
                "name": "naichuan guo",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2011
    },
    "z5sewVrH": {
        "id": "z5sewVrH",
        "title": "Multiple attenuation based on angle‐domain common‐image gathers",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "li zhenchun",
                "org": ""
            },
            {
                "name": "li zhina",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "huimin hao",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2011
    },
    "D8hmPFsQ": {
        "id": "D8hmPFsQ",
        "title": "Study on petrophysical parameters of compacted sandy‐conglomerate",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "huimin hao",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "luo hongmei",
                "org": ""
            },
            {
                "name": "liu shuhui",
                "org": ""
            },
            {
                "name": "mu xing",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2011
    },
    "aW6OCR6J": {
        "id": "aW6OCR6J",
        "title": "Multi‐component wavefield decomposition versus PZ summation: A comparative study",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "sanyu ye",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "huimin hao",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2011
    },
    "LbGKNkCg": {
        "id": "LbGKNkCg",
        "title": "The study of 2D elastic wave forward modeling based on carbonate reservoir",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "qingyang li",
                "org": ""
            },
            {
                "name": "jianping huang",
                "org": ""
            },
            {
                "name": "zhenchun li",
                "org": ""
            },
            {
                "name": "jie zhang",
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    "z2oLBxTB": {
        "id": "z2oLBxTB",
        "title": "Application of the oil‐bearing prediction methods based on spectral decomposition",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "zhou liping",
                "org": ""
            },
            {
                "name": "wang xiaohui",
                "org": ""
            },
            {
                "name": "huimin hao",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "yu baoli",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2012
    },
    "JKyw8t8R": {
        "id": "JKyw8t8R",
        "title": "The analysis for factors affecting the elastic parameters of carbonate rocks",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "huimin hao",
                "org": ""
            },
            {
                "name": "yin xingyao",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "ma zhonggao",
                "org": ""
            },
            {
                "name": "li chengcheng",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2012
    },
    "on3uQhKE": {
        "id": "on3uQhKE",
        "title": "The researching and application of side interference noise attenuation in marine",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "jiang daoqing",
                "org": ""
            },
            {
                "name": "zhang wei",
                "org": ""
            },
            {
                "name": "zhu haihua",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "huimin hao",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2012
    },
    "gXw42LW0": {
        "id": "gXw42LW0",
        "title": "A study on bed resolution of interbedded clastic reservoirs",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "huimin hao",
                "org": ""
            },
            {
                "name": "jiang yan",
                "org": ""
            },
            {
                "name": "chen shumin",
                "org": ""
            },
            {
                "name": "qi jincheng",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2012
    },
    "6mKr4PiQ": {
        "id": "6mKr4PiQ",
        "title": "The seismic sedimentology application research for continental Compresso‐Shear Basin Clastics",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "song chuanchun",
                "org": ""
            },
            {
                "name": "wang shuhua",
                "org": ""
            },
            {
                "name": "huimin hao",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "qiao yulei",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2012
    },
    "1cDaWPm5": {
        "id": "1cDaWPm5",
        "title": "Analysis and evaluation of S/N ratio, resolution and velocity in high‐precision 3D bin‐divisible processing",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "shan lianyu",
                "org": ""
            },
            {
                "name": "wang jing",
                "org": ""
            },
            {
                "name": "zhang junhua",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "huimin hao",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2012
    },
    "gyg9834w": {
        "id": "gyg9834w",
        "title": "Ray tracing and local angle domain prestack depth migration in TI medium",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "duan pengfei",
                "org": ""
            },
            {
                "name": "cheng jiubing",
                "org": ""
            },
            {
                "name": "huimin hao",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2012
    },
    "EjgEAZQh": {
        "id": "EjgEAZQh",
        "title": "A way of arbitrary azimuth fracture estimation",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "yang wuyang",
                "org": ""
            },
            {
                "name": "yong xueshan",
                "org": ""
            },
            {
                "name": "liu junying",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "huimin hao",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2012
    },
    "dynCthpn": {
        "id": "dynCthpn",
        "title": "A case study of 2D seismic exploration on the plateau tundra",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "yanhong zhang",
                "org": ""
            },
            {
                "name": "haizhong tang",
                "org": ""
            },
            {
                "name": "hongxiao ning",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "huimin hao",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2012
    },
    "KDj9CdBe": {
        "id": "KDj9CdBe",
        "title": "Application of frequency‐division impedance inversion to prediction of mound‐bank bodies reservoir in Tazhong area",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "wang zhenqing",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "w u hongbin",
                "org": ""
            },
            {
                "name": "huimin hao",
                "org": ""
            },
            {
                "name": "zhang huquan",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2012
    },
    "4AZkUe0A": {
        "id": "4AZkUe0A",
        "title": "The application of elastic parameter inversion techniques in the rolling exploration and development of Mo109 oilfield",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "ran jianbin",
                "org": ""
            },
            {
                "name": "xing hongge",
                "org": ""
            },
            {
                "name": "yao yanfei",
                "org": ""
            },
            {
                "name": "huimin hao",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2012
    },
    "fJeQMVh6": {
        "id": "fJeQMVh6",
        "title": "Phase space projection with time domain constraint (TDC) for noise reduction",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Xiaodong Luo",
                "org": "Department of Electronic and Information Engineering|Hong Kong Polytechnic University"
            },
            {
                "name": "Jie Zhang",
                "org": "Department of Electronic and Information Engineering|Hong Kong Polytechnic University"
            },
            {
                "name": "Michael Small",
                "org": "Department of Electronic and Information Engineering|Hong Kong Polytechnic University"
            }
        ],
        "venue": "",
        "year": 0
    },
    "2i7ul72x": {
        "id": "2i7ul72x",
        "title": "Nonparametric Rank Test for Nonlinearity Detection",
        "abstract": "In this report we propose a rank test scheme to detect the potential nonlinearity in a scalar time series. Our scheme is based on the fact that, for a stationary linear stochastic process with jointly symmetric innovations, it proves that its ordinary least square (OLS) prediction error of linear autoregressive (AR) predictors are symmetric about zero. With this knowledge, a discriminating statistic, namely the Wilcoxon signed rank statistic, can be derived from the pre- diction error. The advantage of this statistic is that it has a known null distribution, thus we can perform statistical inference of the underlying system with exact confidence level. In addition, the exactness of the null distribution of the rank statistic does not depend on the sample size, which is usually not possessed by many other discriminat- ing statistics such as the correlation dimension. To illus- trate the discriminating power of the test scheme, we ex- amine several examples through our methods.",
        "keywords": [
            "prediction error",
            "statistical inference",
            "time series",
            "stochastic process",
            "ordinary least square",
            "confidence level",
            "sample size",
            "correlation dimension"
        ],
        "authors": [
            {
                "name": "Xiaodong Luo",
                "org": "Department of Electronic and Information Engineering|Hong Kong Polytechnic University"
            },
            {
                "name": "Jie Zhang",
                "org": "Department of Electronic and Information Engineering|Hong Kong Polytechnic University"
            },
            {
                "name": "Michael Small",
                "org": "Department of Electronic and Information Engineering|Hong Kong Polytechnic University"
            }
        ],
        "venue": "",
        "year": 2005
    },
    "YQqvIjBK": {
        "id": "YQqvIjBK",
        "title": "Chaos inducement and Enhancement in Two Particular Nonlinear Maps Using Weak Periodic/quasiperiodic Perturbations",
        "abstract": "",
        "keywords": [
            "periodic perturbation",
            "periodic intermittency.",
            "chaos inducement",
            "two dimensional maps",
            "chaos enhancement"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Michael Small",
                "org": ""
            },
            {
                "name": "Kai Zhang",
                "org": ""
            }
        ],
        "venue": "I. J. Bifurcation and Chaos",
        "year": 2006
    },
    "hIwqEnry": {
        "id": "hIwqEnry",
        "title": "Reducing colored noise for chaotic time series in the local phase space.",
        "abstract": "A two step method is proposed to reduce colored noise for chaotic data in the local phase space. With the observation that the energy of colored noise is mainly distributed in a low dimensional subspace, a noise dominated subspace is first estimated by the energy distribution of colored noise. At step 1, for the reference phase point, the components projected into the noise dominated subspace are deleted and the enhanced data are reconstructed with the remaining components. The residual error of the output of step 1 tends to distribute on each direction uniformly. So at step 2, the local projection method is further applied to the output of step 1, treating the residual error as white noise. Experiments show that our method performs well in eliminating colored noise for chaotic data.",
        "keywords": [],
        "authors": [
            {
                "name": "Junfeng Sun",
                "org": ""
            },
            {
                "name": "Yi Zhao",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Xiaodong Luo",
                "org": ""
            },
            {
                "name": "Michael Small",
                "org": ""
            }
        ],
        "venue": "Physical review. E, Statistical, nonlinear, and soft matter physics",
        "year": 2007
    },
    "g5gdCPWe": {
        "id": "g5gdCPWe",
        "title": "Asymptotically pivotal statistic for surrogate testing with extended\n  hypothesis",
        "abstract": "The method of surrogate data provides a framework for testing observed data\nagainst a hierarchy of alternative hypotheses. The aim of applying this method\nis to exclude the possibility that the data are consistent with simple linear\nexplanations before seeking complex nonlinear causes. However, in recent time\nthe method has attracted considerable criticism, largely as a result of\nambiguity about the formation of the underlying null hypotheses, or about the\npower of the chosen statistic. In this communication we show that by employing\na special family of ranks statistics these problems can be avoided and the\nmethod of surrogate data placed of a firm statistical foundation.",
        "keywords": [
            "surrogate data"
        ],
        "authors": [
            {
                "name": "Xiaodong Luo",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Junfeng Sun",
                "org": ""
            },
            {
                "name": "Michael Small",
                "org": ""
            },
            {
                "name": "Irene Moroz",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2007
    },
    "g51GVIFO": {
        "id": "g51GVIFO",
        "title": "Scale-free networks which are highly assortative but not small world.",
        "abstract": "Uncorrelated scale-free networks are necessarily small world (and, in fact, smaller than small world). Nonetheless, for scale-free networks with correlated degree distribution this may not be the case. We describe a mechanism to generate highly assortative scale-free networks which are not small world. We show that it is possible to generate scale-free networks, with arbitrary degree exponent gamma>1 , such that the average distance between nodes in the network is large. To achieve this, nodes are not added to the network with preferential attachment. Instead, we greedily optimize the assortativity of the network. The network generation scheme is physically motivated, and we show that the recently observed global network of Avian Influenza outbreaks arises through a mechanism similar to what we present here. Simulations show that this network exhibits very similar physical characteristics (very high assortativity, clustering, and path length).",
        "keywords": [],
        "authors": [
            {
                "name": "Michael Small",
                "org": ""
            },
            {
                "name": "Xiaoke Xu",
                "org": ""
            },
            {
                "name": "Jin Zhou",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Junfeng Sun",
                "org": ""
            },
            {
                "name": "Jun-An Lu",
                "org": ""
            }
        ],
        "venue": "Physical review. E, Statistical, nonlinear, and soft matter physics",
        "year": 2008
    },
    "pNt5mybm": {
        "id": "pNt5mybm",
        "title": "Generating an Assortative Network with a Given Degree Distribution",
        "abstract": "",
        "keywords": [
            "Assortativity",
            "Average path length",
            "Clustering coefficient",
            "Complex network",
            "Degree distribution",
            "Rich-club"
        ],
        "authors": [
            {
                "name": "Jin Zhou",
                "org": ""
            },
            {
                "name": "Xiaoke Xu",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Junfeng Sun",
                "org": ""
            },
            {
                "name": "Michael Small",
                "org": ""
            },
            {
                "name": "Jun-an Lu",
                "org": ""
            }
        ],
        "venue": "I. J. Bifurcation and Chaos",
        "year": 2008
    },
    "1i1EHBnx": {
        "id": "1i1EHBnx",
        "title": "Characterizing pseudoperiodic time series through the complex network approach",
        "abstract": "Recently a new framework has been proposed to explore the dynamics of pseudoperiodic time series by constructing a complex network [J. Zhang, M. Small, Phys. Rev. Lett. 96 (2006) 238701]. Essentially, this is a transformation from the time domain to the network domain, which allows for the dynamics of the time series to be studied via organization of the network. In this paper, we focus on the deterministic chaotic Rössler time series and stochastic noisy periodic data that yield substantially different structures of networks. In particular, we test an extensive range of network topology statistics, which have not been discussed in previous work, but which are capable of providing a comprehensive statistical characterization of the dynamics from different angles. Our goal is to find out how they reflect and quantify different aspects of specific dynamics, and how they can be used to distinguish different dynamical regimes. For example, we find that the joint degree distribution appears to fundamentally characterize spatial organizations of cycles in phase space, and this is quantified via an assortativity coefficient. We applied network statistics to electrocardiograms of a healthy individual and an arrythmia patient. Such time series are typically pseudoperiodic, but are noisy and nonstationary and degrade traditional phase-space based methods. These time series are, however, better differentiated by our network-based statistics.",
        "keywords": [
            "pseudoperiodic signal",
            "chaos",
            "complex network transformation",
            "unstable periodic orbits",
            "nonlinear time series analysis",
            "network topology",
            "time series",
            "complex network",
            "time domain",
            "phase space",
            "spatial organization",
            "degree distribution"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Junfeng Sun",
                "org": "Department of Electronic and Information Engineering, Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong"
            },
            {
                "name": "Xiaodong Luo",
                "org": "Oxford Center for Industrial and Applied Mathematics, Mathematical Institute, University of Oxford, Oxford, UK"
            },
            {
                "name": "Kai Zhang",
                "org": "Department of Computer Science and Engineering, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong"
            },
            {
                "name": "Tomomichi Nakamura",
                "org": "Sony Computer Science Laboratories Inc., Tokyo, Japan"
            },
            {
                "name": "Michael Small",
                "org": "Department of Electronic and Information Engineering, Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong"
            }
        ],
        "venue": "Physica D: Nonlinear Phenomena",
        "year": 2008
    },
    "wLPE1GjN": {
        "id": "wLPE1GjN",
        "title": "Effect of heterogeneity for the self-organization of a neural network",
        "abstract": "In this paper, a self-organized neural net- work consisting of neurons with heterogeneous dynam- ics is proposed. The heterogeneity is introduced into the network by choosing the key parameter from a uniform distribution covering a wide variety of neuronal behavior. In particular, the synaptic matrix evolves according to the spike-timing dependent plasticity (STDP) mechanism and finally leads to synchronous spiking and a sparse connec- tion. We argue that the self-emergent topology with active individuals having strong out-degree synapses essentially reflects the competition of different neurons and encodes the heterogeneity. And in order to test the effi ciency of this self-organized network in signal processing, we have made comparisons to three other networks of different topologies in terms of coherence resonance (CR) and stochastic res- onance (SR), which have been analyzed in various neural networks recently. It is shown that the network obtained from STDP learning can enhance the CR and SR of the en- tire network, indicating its high effi ciency in information processing.",
        "keywords": [
            "signal processing",
            "uniform distribution",
            "neural network",
            "self organization",
            "information processing"
        ],
        "authors": [
            {
                "name": "Xiumin Li",
                "org": "Department of Electronic and Information Engineering|Hong Kong Polytechnic University"
            },
            {
                "name": "Jie Zhang",
                "org": "Department of Electronic and Information Engineering|Hong Kong Polytechnic University"
            },
            {
                "name": "Michael Small",
                "org": "Department of Electronic and Information Engineering|Hong Kong Polytechnic University"
            }
        ],
        "venue": "",
        "year": 2008
    },
    "Luxax1ph": {
        "id": "Luxax1ph",
        "title": "Detecting phase synchronization in noisy data from coupled chaotic oscillators.",
        "abstract": "Two schemes are proposed to detect phase synchronization from chaotic data contaminated by noise. The first is a neighborhood-based method which links time delay embedding with instantaneous phase estimation. The second adopts the local projection method as a preprocessing filter to noisy data. Both schemes utilize the state recurrence, an important feature of chaotic data. The proposed schemes are applied to data measured from two typical chaotic systems, i.e., the coupled Rössler systems and the coupled Lorenz systems, respectively. The results show that phase synchronization, which may be buried by noise, is detected even when the noise level is high. Moreover, the overestimation of the degree of phase synchronization, which may be introduced by the Hilbert transform combined with a traditional linear bandpass filter, can be avoided when the data are contaminated by only measurement noise.",
        "keywords": [],
        "authors": [
            {
                "name": "Junfeng Sun",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Jin Zhou",
                "org": ""
            },
            {
                "name": "Xiaoke Xu",
                "org": ""
            },
            {
                "name": "Michael Small",
                "org": ""
            }
        ],
        "venue": "Physical review. E, Statistical, nonlinear, and soft matter physics",
        "year": 2008
    },
    "iQOv7vST": {
        "id": "iQOv7vST",
        "title": "Dynamics and Synchrony from Oscillatory Data via Dimension Reduction",
        "abstract": "Complex, oscillatory data arises from a large variety of biological,\nphysical, and social systems. However, the inherent oscillation and ubiquitous\nnoise pose great challenges to current methodology such as linear and nonlinear\ntime series analysis. We exploit the state of the art technology in pattern\nrecognition and specifically, dimensionality reduction techniques, and propose\nto rebuild the dynamics accurately on the cycle scale. This is achieved by\nderiving a compact representation of the cycles through global optimization,\nwhich effectively preserves the topology of the cycles that are embedded in a\nhigh dimensional Euclidian space. Our approach demonstrates a clear success in\ncapturing the intrinsic dynamics and the subtle synchrony pattern from\nuni/bivariate oscillatory data over traditional methods. Application to the\nhuman locomotion data reveals important dynamical information which allows for\na clinically promising discrimination between healthy subjects and those with\nneural pathology. Our results also provide fundamental implications for\nunderstanding the neuromuscular control of human walking.",
        "keywords": [
            "dimension reduction",
            "social system",
            "oscillations",
            "pattern recognition",
            "global optimization"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Department of Electronic and Information Engineering|Hong Kong Polytechnic University"
            },
            {
                "name": "Kai Zhang",
                "org": "Department of Computer Science and Engineering|Science and Technology"
            },
            {
                "name": "Jianfeng Feng",
                "org": "Department of Computer Science and Mathematics|Warwick University"
            },
            {
                "name": "Junfeng Sun",
                "org": "Department of Electronic and Information Engineering|Hong Kong Polytechnic University"
            },
            {
                "name": "Xiaoke Xu",
                "org": "Department of Electronic and Information Engineering|Hong Kong Polytechnic University"
            },
            {
                "name": "Michael Small",
                "org": "Department of Electronic and Information Engineering|Hong Kong Polytechnic University"
            }
        ],
        "venue": "",
        "year": 2008
    },
    "ktPDlPzI": {
        "id": "ktPDlPzI",
        "title": "Superfamily phenomena and motifs of networks induced from time series.",
        "abstract": "We introduce a transformation from time series to complex networks and then study the relative frequency of different subgraphs within that network. The distribution of subgraphs can be used to distinguish between and to characterize different types of continuous dynamics: periodic, chaotic, and periodic with noise. Moreover, although the general types of dynamics generate networks belonging to the same superfamily of networks, specific dynamical systems generate characteristic dynamics. When applied to discrete (map-like) data this technique distinguishes chaotic maps, hyperchaotic maps, and noise data.",
        "keywords": [
            "dynamic system",
            "time series",
            "complex network",
            "bioinformatics",
            "biomedical research"
        ],
        "authors": [
            {
                "name": "Xiaoke Xu",
                "org": "Department of Electronic and Information Engineering|Hong Kong Polytechnic University"
            },
            {
                "name": "Jie Zhang",
                "org": "Department of Electronic and Information Engineering|Hong Kong Polytechnic University"
            },
            {
                "name": "Michael Small",
                "org": "Department of Electronic and Information Engineering|Hong Kong Polytechnic University"
            }
        ],
        "venue": "Proceedings of the National Academy of Sciences of the United States of America",
        "year": 2008
    },
    "hoT9JmhR": {
        "id": "hoT9JmhR",
        "title": "Mapping from Architecture to Dynamics: A Unified View of Dynamical Processes on Networks",
        "abstract": "",
        "keywords": [
            "structural dynamics",
            "complex system",
            "network topology",
            "topology",
            "complex networks"
        ],
        "authors": [
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "changsong zhou",
                "org": ""
            },
            {
                "name": "xiaoke xu",
                "org": ""
            },
            {
                "name": "michael small",
                "org": ""
            }
        ],
        "venue": "Physical Review E",
        "year": 2009
    },
    "4BRrmPuT": {
        "id": "4BRrmPuT",
        "title": "Transforming Time Series into Complex Networks",
        "abstract": "We introduce transformations from time series data to the domain of complex networks which allow us to characterise the dynamics\n underlying the time series in terms of topological features of the complex network. We show that specific types of dynamics\n can be characterised by a specific prevalence in the complex network motifs. For example, low-dimensional chaotic flows with\n one positive Lyapunov exponent form a single family while noisy non-chaotic dynamics and hyper-chaos are both distinct. We\n find that the same phenomena is also true for discrete map-like data. These algorithms provide a new way of studying chaotic\n time series and equip us with a wide range of statistical measures previously not available in the field of nonlinear time\n series analysis.\n ",
        "keywords": [
            "time series data",
            "time series",
            "complex network",
            "lyapunov exponent"
        ],
        "authors": [
            {
                "name": "Michael Small",
                "org": "Hong Kong Polytechnic University Department of Electronic and Information Engineering"
            },
            {
                "name": "Jie Zhang",
                "org": "Hong Kong Polytechnic University Department of Electronic and Information Engineering"
            },
            {
                "name": "Xiaoke Xu",
                "org": "Hong Kong Polytechnic University Department of Electronic and Information Engineering"
            }
        ],
        "venue": "Complex (2)",
        "year": 2009
    },
    "EEzAUaL7": {
        "id": "EEzAUaL7",
        "title": "Seeding the Kernels in graphs: toward multi-resolution community analysis",
        "abstract": "Current endeavors in community detection suffer from the resolution limit problem and can be quite expensive for large networks, especially those based on optimization schemes. We propose a conceptually different approach for multi-resolution community detection, by introducing the kernels from statistical literature into the graph, which mimic the node interaction that decays locally with the geodesic distance. The modular structure naturally arises as the patterns inherent in the interaction landscape, which can be easily identified by the hill climbing process. The range of node interaction, and henceforth the resolution of community detection, is controlled via tuning the kernel bandwidth in a systematic way. Our approach is computationally efficient and its effectiveness is demonstrated using both synthetic and real networks with multiscale structures.",
        "keywords": [
            "geodesic distance",
            "hill climbing"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Department of Electronic and Information Engineering|Hong Kong Polytechnic University"
            },
            {
                "name": "Kai Zhang",
                "org": "Life Science Division|Lawrence Berkeley National Laboratory"
            },
            {
                "name": "Xiao-ke Xu",
                "org": "Department of Electronic and Information Engineering|Hong Kong Polytechnic University"
            },
            {
                "name": "Chi K Tse",
                "org": "Department of Electronic and Information Engineering|Hong Kong Polytechnic University"
            },
            {
                "name": "Michael Small",
                "org": "Department of Electronic and Information Engineering|Hong Kong Polytechnic University"
            }
        ],
        "venue": "New Journal of Physics",
        "year": 2009
    },
    "2CmqLgtd": {
        "id": "2CmqLgtd",
        "title": "Revising the simple measures of assortativity in complex networks.",
        "abstract": "We find that traditional statistics for measuring degree mixing are strongly affected by superrich nodes. To counteract and measure the effect of superrich nodes, we propose a paradigm to quantify the mixing pattern of a real network in which different mixing patterns may appear among low-degree nodes and among high-degree nodes. This paradigm and the simple revised measure uncover the true complex degree mixing patterns of complex networks with superrich nodes. The alternate method indicates that some networks show a false disassortative mixing induced by superrich nodes and have no tendency to be genuinely disassortative. Our results also show that the previously observed fragility of scale-free networks is actually greatly exacerbated by the presence of even a very small number of superrich nodes.",
        "keywords": [],
        "authors": [
            {
                "name": "Xiao-Ke Xu",
                "org": "School of Communication and Electronics Engineering|Qingdao Technological University"
            },
            {
                "name": "Jie Zhang",
                "org": "Department of Electronic and Information Engineering|Hong Kong Polytechnic University"
            },
            {
                "name": "Junfeng Sun",
                "org": "Med-X Research Institute|Shanghai Jiao Tong University"
            },
            {
                "name": "Michael Small",
                "org": "Department of Electronic and Information Engineering|Hong Kong Polytechnic University"
            }
        ],
        "venue": "Physical review. E, Statistical, nonlinear, and soft matter physics",
        "year": 2009
    },
    "LSBAWOdh": {
        "id": "LSBAWOdh",
        "title": "Two cadmium coordination polymers based on tris(p-carboxyphenyl) phosphane oxide with highly selective sensing of nitrobenzene derivatives and Hg2+ cations",
        "abstract": "Two coordination polymers (CPs), namely, [Cd1/2(L)1/3(bib)1/2(H2O)]n (1) and {[Cd2(HL)2(bibp)2]·3H2O}n (2), have been assembled from the tripodal ligand tris(p-carboxyphenyl)phosphane oxide (H3L) with the help of 1,4-bis(imidazol-1-yl)benzene (bib) or 4,4′-bis(imidazol-1-yl)biphenyl (bibp). Structural analyses revealed that complex 1 is an unprecedented (3,4)-connected {103}2{106}3 net with 2D [Cd3(L)2]n sheets arranged in an ABCA′B′C′A′′B′′C′′ fashion. Complex 2 exhibits 3-fold interpenetrated sheets with a 4-connected {44·62}-sql sheet. Structural comparison reveals that the length of bis(imidazole) ancillary linkers plays a critical role in determining the structures and topologies. To our delight, fluorescence measurements show that the two Cd(II) CPs can selectively and sensitively detect Hg2+ cations and nitrobenzene derivatives (nitrobenzene, p-nitrotoluene, p-nitroaniline, and p-nitrophenol), which suggests that the two Cd(II) CPs are promising bifunctional luminescence sensor materials that could sense metal ions and small organic molecules.",
        "keywords": "",
        "authors": [
            {
                "name": "Liangqin Huo",
                "org": "Department of Chemistry, College of Science, North University of China,Taiyuan 030051,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Department of Chemistry, College of Science, North University of China,Taiyuan 030051,China"
            },
            {
                "name": "Lingling Gao",
                "org": "Department of Chemistry, College of Science, North University of China,Taiyuan 030051,China"
            },
            {
                "name": "Xiaoqing Wang",
                "org": "Department of Chemistry, College of Science, North University of China,Taiyuan 030051,China"
            },
            {
                "name": "Liming Fan",
                "org": "Department of Chemistry, College of Science, North University of China,Taiyuan 030051,China"
            },
            {
                "name": "Kegong Fang",
                "org": "State Key Laboratory of Coal Conversion, Institute of Coal Chemistry, Chinese Academy of Sciences,Taiyuan 030051,China"
            },
            {
                "name": "Tuoping Hu",
                "org": "Department of Chemistry, College of Science, North University of China,Taiyuan 030051,China"
            },
            {
                "name": "Tuoping Hu",
                "org": "Department of Chemistry, College of Science, North University of China,Taiyuan 030051,China"
            }
        ],
        "venue": "CrystEngComm",
        "year": 2017
    },
    "DUJ9QjwJ": {
        "id": "DUJ9QjwJ",
        "title": "Selective sensing of two novel coordination polymers based on tris(4-carboxylphenyl)phosphine oxide for organic molecules and Fe3+ and Hg2+ ions",
        "abstract": "Abstract   Two novel coordination polymers, formulated as {[Zn(HTPO)(bib)]·4H 2 O} n  ( 1 ), {[Cu 3 (TPO) 2  (bib) 3 ]·2DMF·0.5EtOH·0.5H 2 O} n  ( 2 ) (H 3 TPO = tris(4-carboxylphenyl)phosphine oxide; bib = 1,4-bis(1H-imidazol-4-yl) benzene), have been synthesized under solvothermal method and characterized by single-crystal X-ray diffraction, elemental analysis (EA), IR spectra, thermogravimetric (TG) analysis, powder X-ray diffraction (PXRD). Structural analysis reveals that complex  1  is a 2D 4-connected sheet with an intriguing 2D + 2D→2D network. Complex  2  displays a 3D 3,4-connected net with the point symbol of {10 3 } 2 {10 6 } 3 . Furthermore, the photoluminescence properties of  1  and  2  were investigated in the solid state and various solvent emulsions, the results show that  1  and  2  have better fluorescent recognition for organic molecules, Fe 3+  and Hg 2+  ions.",
        "keywords": "",
        "authors": [
            {
                "name": "Liangqin Huo",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan 030051, China"
            },
            {
                "name": "Jie Zhang",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan 030051, China"
            },
            {
                "name": "Lingling Gao",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan 030051, China"
            },
            {
                "name": "Xiaoqing Wang",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan 030051, China"
            },
            {
                "name": "Liming Fan",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan 030051, China"
            },
            {
                "name": "Kegong Fang",
                "org": "State Key Laboratory of Coal Conversion, Institute of Coal Chemistry, Chinese Academy of Sciences, Taiyuan 030051, China"
            },
            {
                "name": "Tuoping Hu",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan 030051, China"
            },
            {
                "name": "Tuoping Hu",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan 030051, China"
            }
        ],
        "venue": "Journal of Solid State Chemistry",
        "year": 2017
    },
    "uHL4ZjFc": {
        "id": "uHL4ZjFc",
        "title": "Gas Adsorption and Fluorescent Sensing Properties of Two Porous Lanthanide Metal-Organic Frameworks Based on 3,5-Bis(2-carboxy-phenoxy)-Benzoic Acid",
        "abstract": "Abstract   Two porous isomorphic 3D Eu(III)/Nd(III) lanthanide metal−organic frameworks (Ln-MOFs), formulated as {[Eu(BCPB)(H 2 O)(DMF)]·H 2 O·1.5CH 3 OH} n  ( 1 ) and {[Nd(BCPB)(H 2 O)(DMF)]·2H 2 O} n  ( 2 ), have been designed and synthesized by using the tripodal ligand of 3,5-bis(2-carboxy-phenoxy)-benzoic acid (H 3 BCPB) under solvothermal condition. Complexes  1  and  2  display 3D (3,6)-c net with the point symbol of {4.6 2 } 2 {4 2 .6 10 .8 3 }. Furthermore, fluorescent measurements showed  1  has highly selective detection for Fe 3+  and CrO 4  2-  ions in aqueous solution, which shows that it acts as a chemical sensor for detecting Fe 3+ /CrO 4  2-  in aqueous solution. Meanwhile, gas adsorption properties of  1  and  2  have also been studied at different temperatures for N 2 , CH 4  and CO 2 .",
        "keywords": "",
        "authors": [
            {
                "name": "Lingling Gao",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan 030051, China"
            },
            {
                "name": "Jie Zhang",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan 030051, China"
            },
            {
                "name": "lijun zhai",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan 030051, China"
            },
            {
                "name": "Xiaoqing Wang",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan 030051, China"
            },
            {
                "name": "Liming Fan",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan 030051, China"
            },
            {
                "name": "Tuoping Hu",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan 030051, China"
            }
        ],
        "venue": "Polyhedron",
        "year": 2018
    },
    "qEwEXfKm": {
        "id": "qEwEXfKm",
        "title": "Three novel coordination polymers based on tris( p -carboxyphenyl)phosphane oxide: Syntheses, structural characterization and magnetic properties",
        "abstract": "Abstract   Three coordination polymers (CPs), namely, {[Co 3 (HL) 2 (bib) 3  (H 2 O) 7 ]·12H 2 O} n  ( 1 ), {[Co(HL)(bib)]·H 2 O} n  ( 2 ), and {[Co 1.5 (L)(bibp) 1.5  (H 2 O)]·1.5DMF·2EtOH·3H 2 O} n  ( 3 ), have been synthesized from the tripodal ligand of tris( p -carboxyphenyl)phosphane oxide (H 3 L) with the help of 1,4-bis(imidazol-1-yl)benzene (bib) or 4,4′-bis(imidazol-1-yl)biphenyl (bibp). Structural analyses reveal that complex  1  features a 3D 4-connected {6 5 0.8}-cds net.  2  displays a 2D 6–connected {3 6 0.4 6 0.5 3 }-hxl sheet based on the binuclear {Co 2 (COO) 2 } SBUs. Complex  3  shows a 3D (3,4,4)-connected net with {6·8 2 } 2 {6·8 4 0.10} 2 {6 2 0.8 2 0.10 2 } point symbol. Furthermore, the results of the variable-temperature magnetic susceptibilities indicate that complexes  1 – 3  have antiferromagnetic behavior between Co(II) ions.",
        "keywords": "",
        "authors": [
            {
                "name": "Liangqin Huo",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan 030051, China"
            },
            {
                "name": "Liming Fan",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan 030051, China"
            },
            {
                "name": "Jie Zhang",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan 030051, China"
            },
            {
                "name": "Lingling Gao",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan 030051, China"
            },
            {
                "name": "Lijun Zhai",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan 030051, China"
            },
            {
                "name": "Xiaoqing Wang",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan 030051, China"
            },
            {
                "name": "Tuo-Ping Hu",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan 030051, China"
            }
        ],
        "venue": "Journal of Solid State Chemistry",
        "year": 2018
    },
    "Zg0Sdkp0": {
        "id": "Zg0Sdkp0",
        "title": "Structural diversity, luminescent and magnetic properties of Tb(III)/Gd(III) metal–organic frameworks constructed by Tris(p-carboxyphenyl)phosphane oxide",
        "abstract": "Abstract   Two lanthanide metal-organic frameworks (LOFs), namely, {[Tb(L 3− ) (H 2 O)]·3CH 3 CN} n  ( 1 ) and {(Me 2 NH 2  + ) 0.5 ·[Gd(L 3− )(HCOO − ) 0.5  H 2 O]·DMF·4EtOH·H 2 O} n  ( 2 ) have been constructed by tris(4-carboxyphenyl)phosphane oxide (H 3 L) under solvothermal conditions. Structural analyses indicate that complex  1  appears a 3D 6-connected {4 12 ∙6 3 } net based on the binuclear {Tb 2 (COO) 2 } clusters. Complex  2  is also a 3D framework. Furthermore, the photoluminescence of  1  in the solid state and different solvent emulsions were studied, the results indicate that  1  shows characteristic green emission of Tb 3+  ion and has better fluorescent recognition for sorts of organic solvent molecules and Fe 3+  ion. Finally, the result of the variable-temperature magnetic susceptibilities suggests that complex  2  have antiferromagnetic behavior between Gd(III) ions.",
        "keywords": "",
        "authors": [
            {
                "name": "Chenxu Jiao",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan 030051, China"
            },
            {
                "name": "Jinfang Liang",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan 030051, China"
            },
            {
                "name": "Lingling Gao",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan 030051, China"
            },
            {
                "name": "Jie Zhang",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan 030051, China"
            },
            {
                "name": "Xiaoqing Wang",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan 030051, China"
            },
            {
                "name": "Liming Fan",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan 030051, China"
            },
            {
                "name": "Tuoping Hu",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan 030051, China"
            }
        ],
        "venue": "Inorganic Chemistry Communications",
        "year": 2018
    },
    "GXmXkN6L": {
        "id": "GXmXkN6L",
        "title": "Five new coordination polymers with a Y-shaped N-heterocyclic carboxylic acid: structural diversity, bifunctional luminescence sensing and magnetic properties",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Jinxia Liang",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan 030051, China"
            },
            {
                "name": "Jie Zhang",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan 030051, China"
            },
            {
                "name": "Jinfang Liang",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan 030051, China"
            },
            {
                "name": "Lijun Zhai",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan 030051, China"
            },
            {
                "name": "Haonan Wu",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan 030051, China"
            },
            {
                "name": "Xiaoyan Niu",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan 030051, China"
            },
            {
                "name": "Tuoping Hu",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan 030051, China"
            }
        ],
        "venue": "CrystEngComm",
        "year": 2019
    },
    "m3EutART": {
        "id": "m3EutART",
        "title": "Gas adsorption and fluorescent sensing properties of three metal-organic frameworks based on 3,5-di(2′,5′-dicarboxylphenyl)benozoic acid and cadmium ions",
        "abstract": "Abstract   Three 3D Cd(Ⅱ) metal-organic frameworks(MOFs), namely, {[Cd 3 (L)(OH)(H 2 O) 3 ] n ·2H 2 O} ( 1 ), {Cd 5 (L) 2 (H 2 O) 9 } n  ( 2 ) and {Cd 2 (L)(bib)(NH 4 )} n  ( 3 ), have been synthesized based on H 5 L and cadmium ion under hydrothermal conditions (H 5 L = 3,5-di(2′,5′-dicarboxylpyl)benozoic acid, bib = 1,4-bis(1-imidazoly)benzene), and characterized by IR spectrum analysis, powder X-ray diffraction analysis (PXRD) and thermogravimetric analysis (TGA). X-ray single crystal diffraction analyses showed that complex  1  is a porous 3D 4-connected net with the point symbol of {4.6 5 } with the trinuclear [Cd 3 (OH)(COO) 5 ] SBUs, complex  2  displays a 3D framework 7-connected net with the point symbol of {3 3 .4 12 .5 5 .6} with the pentanuclear [Cd 5 (COO) 10 (H 2 O) 9 ] SBUs and complex  3  presents a porous 3D 4,6-connected net with the point symbol of {4 3 .6 10 .8 2 }{4 3 .6 3 }. Furthermore, fluorescent measurements indicated that  1  and  2  have potential application in the detection for Fe 3+ , CrO 4  2-  and Cr 2 O 7  2-  ions in aqueous solution. Gas sorption properties exhibited that complex  1  has better hydrogen storage performance.",
        "keywords": "",
        "authors": [
            {
                "name": "Lingling Gao",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan 030051, China"
            },
            {
                "name": "Jie Zhang",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan 030051, China"
            },
            {
                "name": "Lijun Zhai",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan 030051, China"
            },
            {
                "name": "Xiaoyan Niu",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan 030051, China"
            },
            {
                "name": "Tuoping Hu",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan 030051, China"
            }
        ],
        "venue": "Journal of Solid State Chemistry",
        "year": 2019
    },
    "VtSih39e": {
        "id": "VtSih39e",
        "title": "Structural diversity and fluorescent sensing of four novel complexes based on rigid terphenyl-3,3″,5,5″-tetracarboxylic acid",
        "abstract": "Abstract   Based on H 4 TPTC and 1,2-bimb/1,3-bimb ligands, four novel complexes, namely, {[Cu(TPTC)(1,2-bimb) 2 ]·4.5(H 2 O)} n  ( 1 ), [Cu(TPTC) 0.5 (1,3-bimb)] n  ( 2 ), {[Eu 2 (TPTC) 1.5 (H 2 O) 4 ]·4.5(H 2 O)·2(1,4–DOX)} n  ( 3 ) and {[Ce(TPTC)(H 2 O) 4 ]·0.5(H 2 O)·0.5(1,4–DOX)} n  ( 4 ) have been constructed under solvothermal conditions [H 4 TPTC = terphenyl-3,3″,5,5″-tetracarboxylic acid, 1,3-bimb = 1,3-bis (imidazol-1-ylmethyl) benzene, 1,2-bimb = 1,2-bis (imidazol-1-ylmethyl) benzene]. Complexes  1  and  2  are 4-connected 2D networks with the topological types of sql ( 1 ) and kgm ( 2 ). Complex  3  exhibits a 4, 4, 12-connected network with the point symbol of {4 32 .6 34 }{4 4 .6 2 }{4 6 } 2 . Complex  4  presents a 3D supramolecular network through hydrogen bonds. The fluorescent properties of complexes  1  and  3  showed that  1  has good fluorescence sensitivity for Cr 2 O 7  2−  and Fe 3+  ions in aqueous solutions, and  3  can selectively detect NDVs. Furthermore, possible mechanism for luminescence quenching was also investigated.",
        "keywords": "",
        "authors": [
            {
                "name": "Jinxia Liang",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan, 030051, China"
            },
            {
                "name": "Qiannan Zhao",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan, 030051, China"
            },
            {
                "name": "Lingling Gao",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan, 030051, China"
            },
            {
                "name": "Jie Zhang",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan, 030051, China"
            },
            {
                "name": "Xiaoyan Niu",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan, 030051, China"
            },
            {
                "name": "Tuoping Hu",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan, 030051, China"
            }
        ],
        "venue": "Journal of Solid State Chemistry",
        "year": 2019
    },
    "4ugKc6fX": {
        "id": "4ugKc6fX",
        "title": "Fluorescence sensing and magnetic properties of three coordination polymers based on 6-(3,5-dicarboxylphenyl)nicotinic acid and pyridine/imidazole linkers",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Department of Chemistry, College of Science, North University of China,Taiyuan 030051,China"
            },
            {
                "name": "Lingling Gao",
                "org": "Department of Chemistry, College of Science, North University of China,Taiyuan 030051,China"
            },
            {
                "name": "Yang Wang",
                "org": "Department of Chemistry, College of Science, North University of China,Taiyuan 030051,China"
            },
            {
                "name": "Lijun Zhai",
                "org": "Department of Chemistry, College of Science, North University of China,Taiyuan 030051,China"
            },
            {
                "name": "Xiaoqing Wang",
                "org": "Department of Chemistry, College of Science, North University of China,Taiyuan 030051,China"
            },
            {
                "name": "Xiaoyan Niu",
                "org": "Department of Chemistry, College of Science, North University of China,Taiyuan 030051,China"
            },
            {
                "name": "Tuoping Hu",
                "org": "Department of Chemistry, College of Science, North University of China,Taiyuan 030051,China"
            }
        ],
        "venue": "New Journal of Chemistry",
        "year": 2019
    },
    "MSgZ4gOz": {
        "id": "MSgZ4gOz",
        "title": "Luminescent and magnetic properties of two novel coordination polymers based on N-heterocyclic carboxylic acid",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan, 030051, China"
            },
            {
                "name": "Lingling Gao",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan, 030051, China"
            },
            {
                "name": "Yang Wang",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan, 030051, China"
            },
            {
                "name": "Lijun Zhai",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan, 030051, China"
            },
            {
                "name": "Xiaoqing Wang",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan, 030051, China"
            },
            {
                "name": "Xiaoyan Niu",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan, 030051, China"
            },
            {
                "name": "Tuoping Hu",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan, 030051, China"
            }
        ],
        "venue": "Journal of Solid State Chemistry",
        "year": 2019
    },
    "uw7xgf2L": {
        "id": "uw7xgf2L",
        "title": "Structural diversity, magnetic properties, and luminescent sensing of four coordination polymers based on 6-(3,5-dicarboxylphenyl)nicotinic acid",
        "abstract": "Abstract   Four coo;rdination polymers (CPs), namely, [Ni(HDNA)(bibp)(H 2 O)] n  ( 1 ), [Co(HDNA)(bibp)] n  ( 2 ), {[Co(HDNA)(bibp)]·H 2 O} n  ( 3 ) and {[Zn(HDNA)(bibp)]·H 2 O} n  ( 4 ), have been synthesized from the mixed-ligand strategy of 6-(3,5-dicarboxylphenyl)nicotinic acid (H 3 DNA) and 4,4′-bis(benzimidazo-1-ly)benzene (bibp). Structural analyses revealed that four CPs all feature 2D sheets with diverse nets from {4 4 .6 2 }- sql  net ( 1 ), {Co 2 (COO) 2 } SBUs based {4 4 .6 2 }- sql  net ( 2 ), to 4-connected {6 5 .8} sheet ( 3 u0026 4 ). Besides, the temperature-dependent magnetic susceptibilities of CPs  1 - 3  were investigated. And the luminescent sensing indicated CP  4  is a good bifunctional sensor for Fe 3+  and Cr 2 O 7  2-  ions.",
        "keywords": "",
        "authors": [
            {
                "name": "Yujuan Zhang",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan 030051, China"
            },
            {
                "name": "Lingling Gao",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan 030051, China"
            },
            {
                "name": "Jie Zhang",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan 030051, China"
            },
            {
                "name": "Haonan Wu",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan 030051, China"
            },
            {
                "name": "Liming Fan",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan 030051, China"
            },
            {
                "name": "Tuoping Hu",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan 030051, China"
            }
        ],
        "venue": "Journal of Solid State Chemistry",
        "year": 2019
    },
    "B1fwfGSm": {
        "id": "B1fwfGSm",
        "title": "Four 3D metal-organic frameworks formed by 1,4-bis(imidazol-1-yl)terephthalic acid: Synthesis, luminescent sensing and magnetic properties",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Jinxia Liang",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan, 030051, China"
            },
            {
                "name": "Jie Zhang",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan, 030051, China"
            },
            {
                "name": "Jinfang Liang",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan, 030051, China"
            },
            {
                "name": "Lijun Zhai",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan, 030051, China"
            },
            {
                "name": "Xiaoyan Niu",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan, 030051, China"
            },
            {
                "name": "Tuoping Hu",
                "org": "Department of Chemistry, College of Science, North University of China, Taiyuan, 030051, China"
            }
        ],
        "venue": "Journal of Solid State Chemistry",
        "year": 2019
    },
    "HHUUatRt": {
        "id": "HHUUatRt",
        "title": "Compositions and methods for dermally treating neuropathic pain",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "kevin s warner",
                "org": ""
            },
            {
                "name": "sanjay sharma",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2006
    },
    "hmn4vnly": {
        "id": "hmn4vnly",
        "title": "Instant patch for dermal drug delivery",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "kevin s warner",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2006
    },
    "XhBJnBCz": {
        "id": "XhBJnBCz",
        "title": "Compositions and methods for treating dermatological conditions",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "kevin s warner",
                "org": ""
            },
            {
                "name": "sanjay sharma",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2006
    },
    "fH0OH0wp": {
        "id": "fH0OH0wp",
        "title": "Systems and methods for treating warts",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "kevin s warner",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2006
    },
    "KuDaRYqg": {
        "id": "KuDaRYqg",
        "title": "Compositions and methods for treating photo damaged skin",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "kevin s warner",
                "org": ""
            },
            {
                "name": "sanjay sharma",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2007
    },
    "nl6VfjME": {
        "id": "nl6VfjME",
        "title": "Polyvinyl alcohol-containing compositions and methods for dermal delivery of drugs",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "kevin s warner",
                "org": ""
            },
            {
                "name": "sanjay sharma",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2007
    },
    "vJihQddD": {
        "id": "vJihQddD",
        "title": "Compositions and methods for dermally treating infections",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "kevin s warner",
                "org": ""
            },
            {
                "name": "sanjay sharma",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2007
    },
    "IZ4mzx7l": {
        "id": "IZ4mzx7l",
        "title": "Compositions and methods for dermally treating neuropathy with minoxidil",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "kevin s warner",
                "org": ""
            },
            {
                "name": "sanjay sharma",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2008
    },
    "FOiVnECS": {
        "id": "FOiVnECS",
        "title": "Transdermal drug delivery systems for delivering anti-inflammatory drugs",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "kevin s warner",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2009
    },
    "BYaigEGc": {
        "id": "BYaigEGc",
        "title": "Patches, formulations, and associated methods for transdermal delivery of alprazolam and other drugs",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "sanjay sharma",
                "org": ""
            },
            {
                "name": "kevin s warner",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "guang yan",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2009
    },
    "gusg99gs": {
        "id": "gusg99gs",
        "title": "Systems, Methods, and Formulations for Topically Treating Nail Fungal Infections and Nail Psoriasis",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "hyder aliyar",
                "org": ""
            },
            {
                "name": "promod kumar",
                "org": ""
            },
            {
                "name": "kevin s warner",
                "org": ""
            },
            {
                "name": "jie zhang",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2009
    },
    "E5jFXmtC": {
        "id": "E5jFXmtC",
        "title": "TWO OR MORE SOLIDIFYING AGENT-CONTAINING COMPOSITIONS AND METHODS FOR DERMAL DELIVERY OF DRUGS",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "jie zhang",
                "org": ""
            },
            {
                "name": "kevin s warner",
                "org": ""
            },
            {
                "name": "sanjay sharma",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2012
    },
    "gbnZ0v13": {
        "id": "gbnZ0v13",
        "title": "Data Placement for Privacy-Aware Applications over Big Data in Hybrid Clouds.",
        "abstract": "Nowadays, a large number of groups choose to deploy their applications to cloud platforms, especially for the big data era. Currently, the hybrid cloud is one of the most popular computing paradigms for holding the privacy-aware applications driven by the requirements of privacy protection and cost saving. However, it is still a challenge to realize data placement considering both the energy consumption in private cloud and the cost for renting the public cloud services. In view of this challenge, a cost and energy aware data placement method, named CEDP, for privacy-aware applications over big data in hybrid cloud is proposed. Technically, formalized analysis of cost, access time, and energy consumption is conducted in the hybrid cloud environment. Then a corresponding data placement method is designed to accomplish the cost saving for renting the public cloud services and energy savings for task execution within the private cloud platforms. Experimental evaluations validate the efficiency and effectiveness of our proposed method.",
        "keywords": "",
        "authors": [
            {
                "name": "Xiaolong Xu",
                "org": ""
            },
            {
                "name": "Xuan Zhao",
                "org": "Nanjing University"
            },
            {
                "name": "Feng Ruan",
                "org": "Nanjing University"
            },
            {
                "name": "Jie Zhang",
                "org": "Nanjing University"
            },
            {
                "name": "Wei Tian",
                "org": "Nanjing University"
            },
            {
                "name": "Wanchun Dou",
                "org": ""
            },
            {
                "name": "Alex X. Liu",
                "org": "Computer Science and Engineering"
            }
        ],
        "venue": "Security and Communication Networks",
        "year": 2017
    },
    "vxoUOCPV": {
        "id": "vxoUOCPV",
        "title": "DSM: a dynamic scheduling method for concurrent workflows in cloud environment",
        "abstract": "Cloud computing, emerged as a commercial service model, has been widely concerned in both industry and academia. Massive workflow applications could be performed simultaneously on the cloud platforms, which significantly benefits from the elasticity and convenience of cloud computing. However, it is still a challenge to schedule virtualized resources for the concurrent workflows in cloud environment, with limited high-performance resources in a timesaving and efficient manner. In view of this challenge, a dynamic scheduling method for concurrent workflows, named as DSM, in cloud environment is proposed to satisfy the various resource requirements of the workflows. Technically, a time overhead model for the workflows and a resource utilization model for cloud datacenter are presented. Then a relevant dynamic scheduling method is designed based on critical path lookup, which aims at minimizing the makespan of workflows, and maximizing the resource utilization of the datacenter during the execution of the workflows. Extensive experimental evaluations demonstrate the efficiency and effectiveness of our proposed method.",
        "keywords": "",
        "authors": [
            {
                "name": "Shengjun Xue",
                "org": ""
            },
            {
                "name": "Yue Peng",
                "org": "Nanjing University of Information Science and Technology"
            },
            {
                "name": "Xiaolong Xu",
                "org": ""
            },
            {
                "name": "Xiaolong Xu",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": "Nanjing University"
            },
            {
                "name": "Chao Shen",
                "org": "Nanjing University of Information Science and Technology"
            },
            {
                "name": "Feng Ruan",
                "org": ""
            }
        ],
        "venue": "Cluster Computing",
        "year": 2017
    },
    "Xu8sHqkx": {
        "id": "Xu8sHqkx",
        "title": "High Quality Participant Recruitment of Mobile Crowdsourcing over Big Data.",
        "abstract": "With the rich set of embedded sensors installed in smart-phones, an increasing number of applications have been designed based on these mobile sensors rather than on static sensors in urban areas. In Mobile Crowdsourcing (MCS), participant selection is promoted to save energy and entire incentives. Nevertheless, most of the current researches on this problem assume that the system should get the entire information about the participants. As a result, the suitable tasks are always not allocated to the suitable participants. This practice contributes an inaccurate match between a task and participants, which leads to energy and incentives waste. In view of this challenge, we aim to select participants under a more accurate prediction model, rather than assuming that the information of each participant should be obtained in advance. The prediction model is enabled by the big data of participantsu0027 historic evaluation, which are used to predict the user action. Furthermore, a greedy method based on an improved singular value decomposition (SVD), named as SVD_G, is proposed to solve this problem. Finally, the proposed SVD_G method is validated by using the large-scale dataset collected from a real-world project (DaZhongDianPing APP).",
        "keywords": "",
        "authors": [
            {
                "name": "Shu Li",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Dongqing Xie",
                "org": ""
            },
            {
                "name": "Shui Yu",
                "org": ""
            },
            {
                "name": "Wanchun Dou",
                "org": ""
            }
        ],
        "venue": "GLOBECOM",
        "year": 2018
    },
    "6GGVIYIs": {
        "id": "6GGVIYIs",
        "title": "Hybrid computation offloading for smart home automation in mobile cloud computing.",
        "abstract": "Smart home automation enables the users to realize the access control of the in-home appliances by the mobile devices. With the rapid development of mobile cloud computing, offloading computation workloads of the home automation applications to nearby cloudlets has been treated as a promising approach to overcoming inherent flaws of portable devices, such as low battery capacity. The computing capacity of cloudlet is limited compared with the distant public cloud whose elastic computation resources are almost infinite. Therefore, some mobile services should wait for the occupied computation resources in the cloudlet to get released, which is less energy-efficient. In view of this challenge, we model the waiting time spending in the cloudlet as a M/M/m/∞ queue and propose a hybrid computation offloading algorithm for home automation applications to minimize the total energy consumption of the mobile devices within a given constant deadline. The proposed algorithm combines cloudlet with public clouds, providing a more energy-efficient offloading strategy for home automation applications. Technically, a particle swarm optimization (PSO)-based heuristic algorithm is implemented to schedule mobile services. Comprehensive experiments are conducted to demonstrate the effectiveness and efficiency of our proposed algorithm.",
        "keywords": [
            "Home automation",
            " Mobile cloud computing",
            " Cloudlet",
            " Mobile service",
            " Energy consumption"
        ],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "State Key Laboratory for Novel Software Technology,Nanjing University,Nanjing,China"
            },
            {
                "name": "Zhili Zhou",
                "org": "Jiangsu Engineering Centre of Network Monitoring, School of Computer and Software,Nanjing University of Information Science and Technology,Nanjing,China"
            },
            {
                "name": "Shu Li",
                "org": "State Key Laboratory for Novel Software Technology,Nanjing University,Nanjing,China"
            },
            {
                "name": "Leilei Gan",
                "org": "State Key Laboratory for Novel Software Technology,Nanjing University,Nanjing,China"
            },
            {
                "name": "Xuyun Zhang",
                "org": "Department of Electrical and Computer Engineering,The University of Auckland,Auckland,New Zealand"
            },
            {
                "name": "Lianyong Qi",
                "org": "School of Information Science and Engineering, Chinese Academy of Education Big Data,Qufu Normal University,Rizhao,China"
            },
            {
                "name": "Xiaolong Xu",
                "org": "Jiangsu Engineering Centre of Network Monitoring, School of Computer and Software,Nanjing University of Information Science and Technology,Nanjing,China"
            },
            {
                "name": "Wanchun Dou",
                "org": "State Key Laboratory for Novel Software Technology,Nanjing University,Nanjing,China"
            }
        ],
        "venue": "Personal and Ubiquitous Computing",
        "year": 2018
    },
    "eWsqWKvj": {
        "id": "eWsqWKvj",
        "title": "A Workflow Scheduling Method for Cloudlet Management in Mobile Cloud.",
        "abstract": "Cloudlet has emerged as a new paradigm to improve the ability to perform complex computations in mobile cloud computing. However, cloudlet suffers from the challenge of inefficient resource utilization as most of the times it operates below optimum resource utilization conditions. This results in waste of vital resources and increase in computation cost. So keeping in view this challenge, in this paper, a Workflow Scheduling Method (WSM) for cloudlet is proposed, which leverages Genetic Algorithm (GA) for efficient work flow tasks scheduling. Extensive experiments are performed to compare WSM with state of the art work flow task management method MCGA and Benchmark algorithm GA. Experimental evaluation shows that WSM outperforms both techniques and reduce the time cost of workflows and optimize the resource utilization of the cloudlet.",
        "keywords": "",
        "authors": [
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Lianyong Qi",
                "org": ""
            },
            {
                "name": "Yuan Yuan",
                "org": ""
            },
            {
                "name": "Xiaolong Xu",
                "org": ""
            },
            {
                "name": "Wanchun Dou",
                "org": ""
            }
        ],
        "venue": "SmartWorld/SCALCOM/UIC/ATC/CBDCom/IOP/SCI",
        "year": 2018
    },
    "XgaGTdEK": {
        "id": "XgaGTdEK",
        "title": "An incentive mechanism for crowdsourcing markets with social welfare maximization in cloud-edge computing: An Incentive Mechanism for Crowdsourcing Markets in Cloud-Edge Computing",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Xiaolong Xu",
                "org": ""
            },
            {
                "name": "Qing Cai",
                "org": "School of Computer and Software; Nanjing University of Information Science and Technology; Jiangsu China"
            },
            {
                "name": "Guoming Zhang",
                "org": "State Key Laboratory for Novel Software Technology; Nanjing University; Jiangsu China"
            },
            {
                "name": "Jie Zhang",
                "org": "State Key Laboratory for Novel Software Technology; Nanjing University; Jiangsu China"
            },
            {
                "name": "Wei Tian",
                "org": ""
            },
            {
                "name": "Xiaorui Zhang",
                "org": "School of Computer and Software; Nanjing University of Information Science and Technology; Jiangsu China"
            },
            {
                "name": "Alex X. Liu",
                "org": "Department of Computer Science and Engineering; Michigan State University; Michigan"
            }
        ],
        "venue": "Concurrency and Computation: Practice and Experience",
        "year": 2018
    },
    "d1MASQLo": {
        "id": "d1MASQLo",
        "title": "Energy-Efficient Cloudlet Management for Privacy Preservation in Wireless Metropolitan Area Networks.",
        "abstract": "Currently, cloudlet based wireless metropolitan area network (WMAN) is emerging as an effective paradigm to extend the performance of mobile devices, which enables the execution of computational intensive mobile applications. But the normal operation of cloudlets consumes a large amount of energy, which brings about carbon dioxide emissions, aggravation of the greenhouse effect, etc. Meanwhile the data transmission of various mobile users among cloudlets would cause leakage of personal privacy. In view of this challenge, we propose an energy-efficient cloudlet management method, named ECM, for privacy preservation in WMAN. Technically, an optimization model is designed to formalize our problem. Then, based on live virtual machine (VM) migration technique, a corresponding privacy-aware VM scheduling method for energy saving is designed to determine which VMs should be migrated and where they should be migrated. Finally, experimental data demonstrate that the proposed method is both efficient and effective.",
        "keywords": "",
        "authors": [
            {
                "name": "Xiaolong Xu",
                "org": ""
            },
            {
                "name": "Rui Huang",
                "org": "Jinling High School, Nanjing, China"
            },
            {
                "name": "Ruihan Dou",
                "org": "Jinling High School, Nanjing, China"
            },
            {
                "name": "Yuancheng Li",
                "org": "School of Computer and Software, Nanjing University of Information Science and Technology, Nanjing, China"
            },
            {
                "name": "Jie Zhang",
                "org": "State Key Laboratory for Novel Software Technology, Nanjing University, Nanjing, China"
            },
            {
                "name": "Tao Huang",
                "org": "Silicon Lake College, Kunshan, China"
            },
            {
                "name": "Wenbin Yu",
                "org": "School of Computer and Software, Nanjing University of Information Science and Technology, Nanjing, China"
            }
        ],
        "venue": "Security and Communication Networks",
        "year": 2018
    },
    "OrawegjE": {
        "id": "OrawegjE",
        "title": "A Blockchain-Powered Crowdsourcing Method With Privacy Preservation in Mobile Environment",
        "abstract": "Crowdsourcing is a booming technique that enables participants to exchange data directly, thus making it possible to answer latency-sensitive service requests and relieve the burden of core networks. With some incentives, providers compete to furnish service requests, thus pledging the quality of experience (QoE) for requestors. However, the decentralized communication in crowdsourcing increases the probability of information tapering. Furthermore, providers’ arbitrary selection of the requests poses great threat to the efficient and profitable service provision for the requestors. To deal with these challenges, we propose a blockchain-powered crowdsourcing method, named BPCM, while considering the privacy preservation in mobile environment. Specifically, a mobile crowdsourcing framework based on blockchain is designed first to preserve the privacy of the participants and keep the integrity of the service request and provision. Then, density-based spatial clustering of applications with noise (DBSCAN) and improved dynamic programming (IDP) are adopted to cluster the requestors and generate service strategies, respectively. Furthermore, simple additive weighting (SAW) and multiple criteria decision making (MCDM) are utilized to select the optimal strategy that achieves the tradeoffs among maximizing the service time, increasing the profits, and reducing the energy consumption for the providers. Finally, comprehensive experiments are conducted to verify the accuracy and effectiveness of BPCM.",
        "keywords": [
            "Crowdsourcing",
            "Privacy",
            "Blockchain",
            "Task analysis",
            "Device-to-device communication",
            "Data privacy",
            "Quality of experience"
        ],
        "authors": [
            {
                "name": "Xiaolong Xu",
                "org": "School of Computer and Software, Jiangsu Engineering Center of Network Monitoring, Nanjing University of Information Science and Technology, Nanjing, China"
            },
            {
                "name": "Qingxiang Liu",
                "org": "School of Computer and Software, Jiangsu Engineering Center of Network Monitoring, Nanjing University of Information Science and Technology, Nanjing, China"
            },
            {
                "name": "Xuyun Zhang",
                "org": "Department of Electrical and Computer Engineering, The University of Auckland, Auckland, New Zealand"
            },
            {
                "name": "Jie Zhang",
                "org": "State Key Laboratory for Novel Software Technology, Nanjing University, Nanjing, China"
            },
            {
                "name": "Lianyong Qi",
                "org": "School of Information Science and Engineering, Qufu Normal University, Qufu, China"
            },
            {
                "name": "Wanchun Dou",
                "org": "State Key Laboratory for Novel Software Technology, Nanjing University, Nanjing, China"
            }
        ],
        "venue": "IEEE Transactions on Computational Social Systems",
        "year": 2019
    },
    "kXvIdM9E": {
        "id": "kXvIdM9E",
        "title": "An investigation of hygrothermal effects on adhesive materials and double lap shear joints of CFRP composite laminates",
        "abstract": "Abstract   This paper was aimed to investigate the hygrothermal effects on the mechanical behavior of the double lap shear joints of Carbon/Epoxy composite laminates, which were bonded using epoxy adhesive film SY14. First, experimental method was used to evaluate the hygrothermal dependent properties of the adhesive and the static response of composite laminate double lap joints at various environment conditions. The specimens were grouped into room temperature/dry (RD), room temperature/wet (RW), elevated temperature/dry (ED) and elevated temperature/wet (EW). The wet specimens were immersed in deionized water at temperature of 90 °C for 60 h and the elevated temperature is 95 °C. Tensile tests were carried out at room temperature and elevated temperature (95 °C) in a controlled chamber. Results showed that the elastic modulus and tensile strength decreased about 24% and 27% respectively after exposure to humidity environment. And a large degradation was found when exposure to high temperature while the plasticity became notable. The failure modes of the double lap shear joints were studied by visual inspection. It was found that both adhesive and cohesive failure happened for dry specimens at room temperature. While failure modes were dominated by cohesive failure after moisture exposure and adhesive failure at elevated temperature. Second, a finite element model was utilized to simulate the damage evolution of the double lap joints. The moisture diffusion process, swelling stress and thermal stress were included. And hygrothermal dependent cohesive law was considered to study the damage evolution. It revealed that failure modes were highly dependent on the weaker strength of adhesive and cohesive. Moisture absorption caused large degradation in cohesive strength, so the failure modes were mostly cohesive failure. Elevated temperature decreases strength of adhesive seriously, so adhesive failure dominates. Good agreement was achieved between the predicted failure loads and experimental results. And the predicted failure modes were also consistent with the experimental phenomenon.",
        "keywords": "",
        "authors": [
            {
                "name": "Shufeng Liu",
                "org": "School of Aeronautic Science and Engineering, Beihang University, Beijing, China"
            },
            {
                "name": "Xiaoquan Cheng",
                "org": ""
            },
            {
                "name": "Qian Zhang",
                "org": "School of Aeronautic Science and Engineering, Beihang University, Beijing, China"
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Jianwen Bao",
                "org": "Beijing Institute of Aeronautical Materials, Beijing, China"
            },
            {
                "name": "Xin Guo",
                "org": "School of Aeronautic Science and Engineering, Beihang University, Beijing, China"
            }
        ],
        "venue": "Composites Part B-engineering",
        "year": 2016
    },
    "pdghQBSD": {
        "id": "pdghQBSD",
        "title": "Effect of damage on failure mode of multi-bolt composite joints using failure envelope method",
        "abstract": "Abstract   Failure envelope method is comprehensively used in failure mode prediction of multi-bolt composite joints. The method is based on the assumption that bolt load distribution proportion is constant till failure. However, bearing damage and net-section damage must have some influence on the load distribution and then change structure failure mode. In this paper, tensile experiments of two-bolt and three-bolt joints were conducted to obtain the failure modes and other properties. Three dimensional (3D) finite element models involving damage were constructed, and the results were consistent with experimental data. Then, the models were used to study the effect of damage on failure mode of multi-bolt composite joints. The results show that failure mode prediction with failure envelope method should involve the effect of composite damage. Compared with net-section damage, bearing damage has greater influence on failure mode. Based on conventional failure envelope method, a new evaluation procedure involving damage was proposed.",
        "keywords": "",
        "authors": [
            {
                "name": "Xiaoquan Cheng",
                "org": ""
            },
            {
                "name": "Songwei Wang",
                "org": "School of Aeronautic Science and Engineering, Beihang University, Beijing 100191, China"
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Wenjun Huang",
                "org": "AVIC China Helicopter Research and Development Institute, 333001 Jingdezhen, China"
            },
            {
                "name": "Yujia Cheng",
                "org": "School of Aeronautic Science and Engineering, Beihang University, Beijing 100191, China"
            },
            {
                "name": "Jikui Zhang",
                "org": "School of Aeronautic Science and Engineering, Beihang University, Beijing 100191, China"
            }
        ],
        "venue": "Composite Structures",
        "year": 2017
    },
    "kcDedNdg": {
        "id": "kcDedNdg",
        "title": "Effects of stacking sequence and rotation angle of patch on low velocity impact performance of scarf repaired laminates",
        "abstract": "Abstract   In this paper, a 3D progressive finite element model was established to simulate scarf repaired laminates subjected to low velocity impact, in which intralaminar damage evolution was captured by user-defined subroutine and interlaminar delamination was simulated via the failure of zero-thickness cohesive elements inserted between plies. By comparison, the numerical results are in good agreement with experimental results. Based on the validated model, the effects of patch stacking sequence and rotation angle on low velocity performances (impact loads and damages) of scarf repaired laminates were investigated respectively. Both of them have effects on the impact performance of scarf repaired laminates, but patch rotation angle has greater effect than patch stacking sequence.",
        "keywords": "",
        "authors": [
            {
                "name": "Xiaoquan Cheng",
                "org": "School of Aeronautic Science and Engineering, Beihang University, Beijing, 100191, China"
            },
            {
                "name": "Xiaoquan Cheng",
                "org": "School of Aeronautic Science and Engineering, Beihang University, Beijing, 100191, China"
            },
            {
                "name": "Xiaoyuan Du",
                "org": "School of Aeronautic Science and Engineering, Beihang University, Beijing, 100191, China"
            },
            {
                "name": "Jie Zhang",
                "org": "School of Aeronautic Science and Engineering, Beihang University, Beijing, 100191, China"
            },
            {
                "name": "Jikui Zhang",
                "org": "School of Aeronautic Science and Engineering, Beihang University, Beijing, 100191, China"
            },
            {
                "name": "Jikui Zhang",
                "org": "School of Aeronautic Science and Engineering, Beihang University, Beijing, 100191, China"
            },
            {
                "name": "Xin Guo",
                "org": "School of Aeronautic Science and Engineering, Beihang University, Beijing, 100191, China"
            },
            {
                "name": "Jianwen Bao",
                "org": "Science and Technology on Advanced Composites Laboratory, BIAM, AVIC Composite Center, AVIC Composite Corporation LTD, Beijing, 100095, China"
            }
        ],
        "venue": "Composites Part B-engineering",
        "year": 2018
    },
    "LqxxQnIJ": {
        "id": "LqxxQnIJ",
        "title": "Buckling and post-buckling behaviors of 1/3 composite cylindrical shell with an opening",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Yihao Ma",
                "org": ""
            },
            {
                "name": "Xiaoquan Cheng",
                "org": ""
            },
            {
                "name": "Zhaodi Wang",
                "org": ""
            },
            {
                "name": "Xin Guo",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Yahong Xu",
                "org": ""
            }
        ],
        "venue": "Steel and Composite Structures",
        "year": 2018
    },
    "5F7yZxp2": {
        "id": "5F7yZxp2",
        "title": "Low-velocity impact performance and effect factor analysis of scarf-repaired composite laminates",
        "abstract": "Abstract   Low-velocity impact performance of scarf-repaired composite laminates was investigated by experimental and numerical methods. The numerical model was built using continuum damage mechanics and cohesive elements were used in all the interfaces of the adherends (i.e. the patch and the parent). The model was verified to be efficient. Based on it, damage profiles and damage mechanism were studied, and the effects of the scarf angle, the adhesive thickness and the patch off-axis angles were analyzed. Results show that the patch damage occurs in its center region through the thickness, while the damages in the parent and adhesive mainly occur around the back face. Damage area of the patch is obviously more serious than that of the parent, and the adhesive can protect the parent to some degree. The scarf angle, the adhesive thickness and the patch off-axis angles have effects on the impact properties. The scarf angles ranging from 7° to 8°, the adhesive thicknesses of 0.15 mm, the patch off-axis angles ranging from 135° to 160° are recommended for better impact performances.",
        "keywords": "",
        "authors": [
            {
                "name": "Xiaoquan Cheng",
                "org": "School of Aeronautic Science and Engineering, Beihang University, Beijing, 100191, China"
            },
            {
                "name": "Jie Zhang",
                "org": "School of Aeronautic Science and Engineering, Beihang University, Beijing, 100191, China"
            },
            {
                "name": "Jianwen Bao",
                "org": "Science and Technology on Advanced Composites Laboratory, BIAM, AVIC Composite Center, AVIC Composite Corporation LTD, Beijing, 100095, China"
            },
            {
                "name": "Benyin Zeng",
                "org": "Helicopter Research and Development Institute, Aviation Industry Corporation of China, Jingdezhen, 333001, China"
            },
            {
                "name": "Yujia Cheng",
                "org": "School of Aeronautic Science and Engineering, Beihang University, Beijing, 100191, China"
            },
            {
                "name": "Renwei Hu",
                "org": "School of Aeronautic Science and Engineering, Beihang University, Beijing, 100191, China"
            }
        ],
        "venue": "International Journal of Impact Engineering",
        "year": 2018
    },
    "cjU9fw3g": {
        "id": "cjU9fw3g",
        "title": "Effect of environment conditions on adhesive properties and material selection in composite bonded joints",
        "abstract": "Abstract   Adhesives have been widely used in aircraft composite bonded structures, which are required to stand severe environment conditions involving high temperature and moisture during the service. Current relevant investigations focus on the environment effects on adhesive specific properties with little attention to adhesive material selection in different environment conditions. In this paper, the properties of two types of adhesives from the same material system, SY14M (an elevated temperature curing epoxy adhesive) and SY24C (a medium temperature curing epoxy adhesive), were studied in different environment conditions. An adhesive selection method based on property matching between adhesive tensile and shear strength in different environment conditions was proposed. Results show that hydrolysis reaction can cause adhesive color variation, moisture absorption acceleration and plasticity decrease. Thermal effect on tensile properties of the adhesives is greater than that on shear properties, while moisture effect is opposite. High temperature can extremely increase adhesive plasticity, especially for tough adhesive. For the two adhesives, the matching consistency between tensile and shear strength is different in different environment conditions, so environment conditions must be considered in the adhesive selection.",
        "keywords": "",
        "authors": [
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Xiaoquan Cheng",
                "org": ""
            },
            {
                "name": "Xin Guo",
                "org": ""
            },
            {
                "name": "Jianwen Bao",
                "org": ""
            },
            {
                "name": "Wenjun Huang",
                "org": ""
            }
        ],
        "venue": "International Journal of Adhesion and Adhesives",
        "year": 2018
    },
    "dcnrW54b": {
        "id": "dcnrW54b",
        "title": "Parameters prediction of cohesive zone model for simulating composite/adhesive delamination in hygrothermal environments",
        "abstract": "Abstract   In this paper, moisture parameters of adhesive SY-14M-III and composite T800/AC531 were firstly measured, which were used for the following moisture diffusion investigations. Then, double cantilever beam (DCB) tests and end notched flexure (ENF) tests were conducted in four environments, and relevant progressive damage models considering cohesive zone models were established. The results show that the models are efficient by comparison of experimental and numerical results, and eight pairs of cohesive parameters (interface strength and interface stiffness) corresponding to the specified fracture energy release rates were obtained. Finally, a modified Tsai prediction method of cohesive zone model for simulating composite/adhesive delamination in hygrothermal environments was proposed based on an assumption of the composite/adhesive moisture diffusion process, which can be as a reference or basic data for numerical analysis of adhesively bonded composite structures.",
        "keywords": "",
        "authors": [
            {
                "name": "Xiaoquan Cheng",
                "org": ""
            },
            {
                "name": "Qian Zhang",
                "org": ""
            },
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Xin Guo",
                "org": ""
            },
            {
                "name": "Zhongrong Niu",
                "org": ""
            }
        ],
        "venue": "Composites Part B-engineering",
        "year": 2019
    },
    "jM3HA8kI": {
        "id": "jM3HA8kI",
        "title": "Detemination of cryptotanshinone content in β-cyclic dextrin tanshinone ear drops by using HPLC",
        "abstract": "Objective To develop a quantitative method for determination of cryptotanshinone content inβ-cyclic dextrin tanshinone ear drops.Methods High-performance layer chromatography was used in this study.The chromatographic conditions included lntersil C18 column,mobile phase: acetonitrile and 10% acetonitrile(55∶45),flow rate 1.0 ml/min and wavelength 263 nm.Results The number of theoretical plates calculated by cryptotaashinone peak was 8000;The regression equation of cryptotanshinone was Y=-0.6242+(0.000 000 785 9)X(r=0.9998) and the liner range was 12.93~64.64 μg/ml.The average recovery of cryptotanshinone was 98.8%(RSD 1.9 %).The measurable lowest limit of cryptotanshinone was 0.1 μg/ml. Conclusions The method is sensitive,rapid and accurate for the measurement of cryptotanshinone content in β-cyclic dextrin tanshinone ear drops.",
        "keywords": [
            "HPLC β-cyclic dextrin Tanshinone ear drops Cryptotanshinone"
        ],
        "authors": [
            {
                "name": "LIU Chang-ye",
                "org": ",et al.Department of Pharmacy,306 Hospital of PLA,Beijing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": ",et al.Department of Pharmacy,306 Hospital of PLA,Beijing ,China"
            },
            {
                "name": "JIANG Ren",
                "org": ",et al.Department of Pharmacy,306 Hospital of PLA,Beijing ,China"
            }
        ],
        "venue": "Medical Journal of General Equipment Headquarters",
        "year": 2006
    },
    "ZTPUbTB9": {
        "id": "ZTPUbTB9",
        "title": "Determination of baicalein in Gujing pill by HPLC",
        "abstract": "Objective To develop a quantitative method for the determination of baicalein in Gujing pill by HPLC. Methods Baicalein was chromatographed on a YWG-NH2 column (4.6 mm ID×250 mm, 5 μm) using a mixture of acetonitrile and water (26∶74 v·v -1 ), which was adjusted to pH 2.6 by phosphoric acid, and monitored at 276 nm with a flow rate of 1.0 ml·min -1 . Results The number of theoretical plates calculated by baicalein peak was 2950. The regression equation was y=796121.5 x +621926.0 (r=0.9999), which was linear over a range from 20.20 μg·ml -1 to 202.0 μg·ml -1 . The average recovery was 100.5% (n=6, RSD 2.1%). Conclusion The method is proved to be sensitive, rapid and accurate.",
        "keywords": [
            "HPLC Gujing pill Baicalein"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": ", et al. Department of Pharmacy, 306 Hospital of PLA, Beijing , China"
            },
            {
                "name": "ZHANG Yan-ping",
                "org": ", et al. Department of Pharmacy, 306 Hospital of PLA, Beijing , China"
            },
            {
                "name": "LIU Chang-ye",
                "org": ", et al. Department of Pharmacy, 306 Hospital of PLA, Beijing , China"
            }
        ],
        "venue": "Medical Journal of General Equipment Headquarters",
        "year": 2006
    },
    "4BhiTZ3z": {
        "id": "4BhiTZ3z",
        "title": "A Comparison of two Methods of Preparing the Rapidly Dissolving Tablets of Oxycodone Hydrochloride",
        "abstract": "Aim To prepare rapidly-dssolving tablets of Oxycodone Hydrochloride. Methods Two kinds of granules were obtained by the fluidiz-bed granulation and traditional wet granulation. The appearance, flow ability, diameter distribution and pore structure of the two kinds of granules were compared.The granule was compressed to get rapidly dissolving tablets,and the disintegration time of the tablets was compared. Results Flow index was investigated, the uniformity, compressibility and flow ability of the granule made by the fluid-bed granulation were better than those of the traditional wet granulation.The rapidly dissolving tablets made by fluid-bed distintegrated faster than traditional wet granulation.Conclusion It was an ideal method to prepare rapidly-dissolving tablets of Oxycodone Hydrochloride by fluid-bed granulation.The high porosity of the granule might account for the fast dissolving effect.",
        "keywords": [
            "Oxycodone Hydrochloride",
            "Rapidly dissolving tablet",
            "Fluid-bed"
        ],
        "authors": [
            {
                "name": "SHI Ning",
                "org": "①Department of Pharmacy,Hospital 306 of PLA,Beijing  China"
            },
            {
                "name": "WU Jiu-Hong",
                "org": "①Department of Pharmacy,Hospital 306 of PLA,Beijing  China"
            },
            {
                "name": "ZHANG Jie",
                "org": "①Department of Pharmacy,Hospital 306 of PLA,Beijing  China"
            },
            {
                "name": "WANG Huan",
                "org": "①Department of Pharmacy,Hospital 306 of PLA,Beijing  China"
            },
            {
                "name": "LIU Chang-Ye",
                "org": "①Department of Pharmacy,Hospital 306 of PLA,Beijing  China"
            }
        ],
        "venue": "Pharmaceutical Journal of Chinese People's Liberation Army",
        "year": 2008
    },
    "2WSxCIZf": {
        "id": "2WSxCIZf",
        "title": "Simultaneous determination of chlorogenic acid and baicalin in Yinhuang oral liquid by HPLC",
        "abstract": "Objective:To develop a HPLC quantitative method for the determination of chlorgenic acid and baicalin in Yinhuang Oral liquid.Methods: An Agilent C18 column(ZORBAX Eclipse XDB-C18,4.6×150 mm,5 μm)was used and a mixture of methanol-water-phosphorc acid(50:950:5)was used as mobile phase A,methanol as mobile phase B,gradient elution:0～30,A:95%～35%,B:5%～65%.The flow rate was 1.0 mL/min and monitored at 327 nm.Results: The retention time of chlorgenic acid and baicalin were 10.5 min and 23.8 min,respectively.The regress equation for chlorgenic acid was Y=0.032 00X-0.021 60,r=0.999 9,and the linear range was 5.040～45.36 μg/mL.Baicalin was Y=0.049 70X-0.488 0,r=0.999 9 and the linear range was 44.88～403.9 μg/mL.The average recovery of chlorgenic acid and baicalin were(n=6)95.7% and 99.0%;RSD 0.43% and 0.33% respectively.Conclusion: Between the determination of this method in CP 2005,this method was sensiteve,time-saving and accurate.",
        "keywords": [
            "baicalin",
            "HPLC",
            "chlorgenic acid",
            "Yinhuang oral liquid"
        ],
        "authors": [
            {
                "name": "TAN Sheng-jian",
                "org": "Department of Pharmacy,No.306th Hospital of PLA,Beijing ,China"
            },
            {
                "name": "LIU Gang",
                "org": "Department of Pharmacy,No.306th Hospital of PLA,Beijing ,China"
            },
            {
                "name": "ZHANG Jie",
                "org": "Department of Pharmacy,No.306th Hospital of PLA,Beijing ,China"
            },
            {
                "name": "LIU Chang-ye",
                "org": "Department of Pharmacy,No.306th Hospital of PLA,Beijing ,China"
            },
            {
                "name": "PAN Min-xiang",
                "org": "Department of Pharmacy,No.306th Hospital of PLA,Beijing ,China"
            },
            {
                "name": "CHANG Hua",
                "org": "Department of Pharmacy,No.306th Hospital of PLA,Beijing ,China"
            }
        ],
        "venue": "Journal of Pharmaceutical Practice",
        "year": 2008
    },
    "c1Xl2NPb": {
        "id": "c1Xl2NPb",
        "title": "Analysis of Drug Utilization in Our Hospital During the Period 2003～2008",
        "abstract": "OBJECTIVE:To analyze the current situation and developing trend of drug utilization in our hospital in order to provide a reference for clinical rational drug use. METHODS: The drug consumption data in our hospital from 2003 to 2008 were analyzed statistically. RESULTS: The drug consumption sum increased year after year from 2003 to 2008,with an annual growth rate of up to 48.69%. The consumption sum of antimicrobical agents dominated the first place over the 6 years. Antimicrobical agents,nervous system agents and cardiovascular system agents ranked among the lead of the top 20 drugs on the consumption sum list. The consumption sum of Chinese medicine injection agents was high,and monitoring on their ADRs should be intensified. CONCLUSION: The clinical drug utilization in our hospital is satisfactory,however,the use of antimicrobical agents and nervous system agents were on the higher side. It is imperative to tighten control on drug use to ensure economical,safe and effective drug use.",
        "keywords": [
            "Analysis of drug use",
            "Pharmceutical care",
            "Consumption sum"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Dept. of Pharmacy,No. 306 Hospital of PLA,Beijing ,China"
            },
            {
                "name": "LIU Chang-ye",
                "org": "Dept. of Pharmacy,No. 306 Hospital of PLA,Beijing ,China"
            },
            {
                "name": "WANG Huan",
                "org": "Dept. of Pharmacy,No. 306 Hospital of PLA,Beijing ,China"
            },
            {
                "name": "DONG Ji-yan",
                "org": "Dept. of Pharmacy,No. 306 Hospital of PLA,Beijing ,China"
            }
        ],
        "venue": "Evaluation and Analysis of Drug-Use in Hospitals of China",
        "year": 2010
    },
    "ECX8RxA3": {
        "id": "ECX8RxA3",
        "title": "HPLC determination of hesperidin and baicalin in Xiao'er Runfeizhike oral liquid",
        "abstract": "Objective:To develop an HPLC quantitative method for the determination of hesperidin and baicalin in Xiao'er Runfeizhike oral liquid.Methods:Column C18(150 mm×4.6 mm,5 μm),0.5% phosphoric acid(include 5% methanol)as mobile phase A,methanol as mobile phase B at flow rate of 1 mL·min-1.Gradient elution:0-45 min,A:90%→60%,B:10%→40%;and monitored at 284 nm.Results:The regress equation for hesperidin was Y=0.05488X+0.01433,r=0.9999 and the linear range was 2.690-33.63 μg·mL-1,The average recovery of hesperidin was 97.2%,RSD 1.1%.The regress equation for baicalin was Y=0.03710X+0.03698,r=0.9999 and the linear range was 7.969-99.61 μg·mL-1,The average recovery of baicalin was 101.3%,RSD 0.60%.Conclusion:This method is simple,time-saving and accurate.It can be used for routine analysis of hesperidin and baicalin in Xiao'er Runfeizhike Koufuye.",
        "keywords": [
            "baicalin",
            "HPLC",
            "Xiao'er Runfeizhike oral liquid",
            "hesperidin"
        ],
        "authors": [
            {
                "name": "ZHANG Jie",
                "org": "Department of Pharmacy,Hospital 306 of PLA,Beijing ,China"
            },
            {
                "name": "TAN Sheng-jian",
                "org": "Department of Pharmacy,Hospital 306 of PLA,Beijing ,China"
            },
            {
                "name": "WANG huan",
                "org": "Department of Pharmacy,Hospital 306 of PLA,Beijing ,China"
            },
            {
                "name": "LIU Chang-ye",
                "org": "Department of Pharmacy,Hospital 306 of PLA,Beijing ,China"
            },
            {
                "name": "SONG Jing",
                "org": "Department of Pharamacy Medical College of Cangzhou,Cangzhou ,China"
            },
            {
                "name": "HU Qin",
                "org": "Department of Pharamacy Hubei University of Traditional Chinese Medicine,Wuhan ,China"
            }
        ],
        "venue": "Chinese Journal of Pharmaceutical Analysis",
        "year": 2010
    },
    "jZdtc1sR": {
        "id": "jZdtc1sR",
        "title": "Collaborated Online Change-Point Detection in Sparse Time Series for Online Advertising",
        "abstract": "Online advertising delivers promotional marketing messages to consumers through online media. Advertisers often have the desire to optimize their advertising spending and strategies in order to maximize their KPI (Key performance indicator). To build accurate ad performance predictive models, it is crucial to detect the change-points in historical data and therefore apply appropriate strategies to address the data pattern shift. However, with sparse data, which is common in online advertising, online change-point detection often becomes challenging. We propose a novel collaborated online change-point detection method in this paper. Through efficiently leveraging and coordinating with auxiliary time series, it can quickly and accurately identify the change-points in sparse and noisy time series. Simulation studies as well as real data applications have demonstrated its effectiveness in detecting change-point in sparse time series and therefore improving the accuracy of predictive models.",
        "keywords": [],
        "authors": [
            {
                "name": "Jie Zhang",
                "org": ""
            },
            {
                "name": "Zhi Wei",
                "org": ""
            },
            {
                "name": "Zhenyu Yan",
                "org": ""
            },
            {
                "name": "Abhishek Pani",
                "org": ""
            }
        ],
        "venue": "IEEE International Conference on DataMining",
        "year": 2015
    },
    "U0U5cyyc": {
        "id": "U0U5cyyc",
        "title": "Online Change-Point Detection in Sparse Time Series With Application to Online Advertising",
        "abstract": "Online advertising delivers promotional marketing messages to consumers through online media. Advertisers often have the desire to optimize their advertising spending strategies in order to gain the highest return on investment and maximize their key performance indicator. To build accurate advertisement performance predictive models, it is crucial to detect the change-points in the historical data and apply appropriate strategies to address a data pattern shift problem. However, with sparse data, which is common in online advertising and some other applications, online change-point detection is very challenging. We present a novel collaborated online change-point detection method in this paper. Through efficiently leveraging and coordinating with auxiliary time series, we can quickly and accurately identify the change-points in sparse and noisy time series. Simulation studies as well as real data experiments have justified the proposed methodu0027s effectiveness in detecting change-points in sparse time series. Therefore, it can be used to improve the accuracy of predictive models.",
        "keywords": "",
        "authors": [
            {
                "name": "Jie Zhang",
                "org": "Adobe Systems, Inc., San Jose, CA 95110 USA."
            },
            {
                "name": "Zhi Wei",
                "org": "Department of Computer Science, New Jersey Institute of Technology, Newark, NJ 07102 USA."
            },
            {
                "name": "Zhenyu Yan",
                "org": "Adobe Systems, Inc., San Jose, CA 95110 USA."
            },
            {
                "name": "MengChu Zhou",
                "org": "Macau University of Science and Technology"
            },
            {
                "name": "Abhishek Pani",
                "org": "Adobe Systems, Inc., San Jose, CA 95110 USA."
            }
        ],
        "venue": "IEEE Transactions on Systems, Man, and Cybernetics",
        "year": 2017
    },
    "xsMAR1LP": {
        "id": "xsMAR1LP",
        "title": "MSX1-Induced Neural Crest-Like Reprogramming Promotes Melanoma Progression.",
        "abstract": "Melanoma cells share many biological properties with neural crest stem cells. Here we show that the homeodomain transcription factor MSX1, which is significantly correlated with melanoma disease progression, reprograms melanocytes and melanoma cells toward a neural crest precursor-like state. MSX1-reprogrammed normal human melanocytes express the neural crest marker p75 and become multipotent. MSX1 induces a phenotypic switch in melanoma, which is characterized by an oncogenic transition from an E-cadherin-high nonmigratory state toward a ZEB1-high invasive state. ZEB1 up-regulation is responsible for the MSX1-induced migratory phenotype in melanoma cells. Depletion of MSX1 significantly inhibits melanoma metastasis in vivo. These results show that neural crest-like reprogramming achieved by a single factor is a critical process for melanoma progression.",
        "keywords": "",
        "authors": [
            {
                "name": "Markus V Heppt",
                "org": "The Wistar Institute, Philadelphia, Pennsylvania, USA; Department of Dermatology and Allergology, Ludwig-Maximilian University, Munich, Germany."
            },
            {
                "name": "Joshua X Wang",
                "org": "The Wistar Institute, Philadelphia, Pennsylvania, USA."
            },
            {
                "name": "Denitsa M Hristova",
                "org": "The Wistar Institute, Philadelphia, Pennsylvania, USA."
            },
            {
                "name": "Zhi Wei",
                "org": "Department of Computer Science, New Jersey Institute of Technology, Newark, New Jersey, USA."
            },
            {
                "name": "Ling Li",
                "org": "The Wistar Institute, Philadelphia, Pennsylvania, USA."
            },
            {
                "name": "Brianna Evans",
                "org": "The Wistar Institute, Philadelphia, Pennsylvania, USA."
            },
            {
                "name": "Marilda Beqiri",
                "org": "The Wistar Institute, Philadelphia, Pennsylvania, USA."
            },
            {
                "name": "Samir Zaman",
                "org": "The Wistar Institute, Philadelphia, Pennsylvania, USA."
            },
            {
                "name": "Jie Zhang",
                "org": "Department of Computer Science, New Jersey Institute of Technology, Newark, New Jersey, USA."
            },
            {
                "name": "Martin Irmler",
                "org": "Institute of Experimental Genetics, Helmholtz Zentrum München GmbH, Neuherberg, Germany."
            },
            {
                "name": "Carola Berking",
                "org": "Department of Dermatology and Allergology, Ludwig-Maximilian University, Munich, Germany."
            },
            {
                "name": "Robert Besch",
                "org": "Department of Dermatology and Allergology, Ludwig-Maximilian University, Munich, Germany."
            },
            {
                "name": "Johannes Beckers",
                "org": "Institute of Experimental Genetics, Helmholtz Zentrum München GmbH, Neuherberg, Germany; German Center for Diabetes Research (DZD), Neuherberg, Germany; Technische Universität München, Chair of Experimental Genetics, Freising, Germany."
            },
            {
                "name": "Frank J Rauscher",
                "org": "The Wistar Institute, Philadelphia, Pennsylvania, USA."
            },
            {
                "name": "Rick A Sturm",
                "org": "Dermatology Research Centre, The University of Queensland, School of Medicine, Translational Research Institute, Brisbane, Queensland, Australia."
            },
            {
                "name": "David E Fisher",
                "org": "Cutaneous Biology Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA."
            },
            {
                "name": "Meenhard Herlyn",
                "org": "The Wistar Institute, Philadelphia, Pennsylvania, USA. Electronic address: herlynm@wistar.org."
            },
            {
                "name": "Mizuho Fukunaga-Kalabis",
                "org": "The Wistar Institute, Philadelphia, Pennsylvania, USA. Electronic address: mkalabis@wistar.org."
            }
        ],
        "venue": "The Journal of investigative dermatology",
        "year": 2017
    },
    "N9e8ndCc": {
        "id": "N9e8ndCc",
        "title": "Loss of Phd2 cooperates with BRAF V600E to drive melanomagenesis",
        "abstract": "Prolyl hydroxylase domain protein 2 (PHD2) is a well-known master oxygen sensor. However, the role of PHD2 in tumor initiation remains controversial. We find that during the transition of human nevi to melanoma, the expression of PHD2 protein is significantly decreased and lower expression PHD2 in melanoma is associated with worse clinical outcome. Knockdown of PHD2 leads to elevated Akt phosphorylation in human melanocytes. Mice with conditional melanocyte-specific expression of Phd2lox/lox (Tyr::CreER;Phd2lox/lox) fail to develop pigmented lesions. However, deletion of Phd2 in combination with expression of BRafV600E in melanocytes (Tyr::CreER;Phd2lox/lox;BRafCA) leads to the development of melanoma with 100% penetrance and frequent lymph node metastasis. Analysis of tumor tissues using reverse phase protein arrays demonstrates that Phd2 deletion activates the AKT-mTOR-S6 signaling axis in the recovered tumors. These data indicate that PHD2 is capable of suppressing tumor initiation largely mediated through inhibiting of the Akt-mTOR signaling pathway in the melanocyte lineage.",
        "keywords": "",
        "authors": [
            {
                "name": "Shujing Liu",
                "org": "Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA"
            },
            {
                "name": "Gao Zhang",
                "org": "The Wistar Institute, Philadelphia, USA"
            },
            {
                "name": "Jianping Guo",
                "org": "Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA"
            },
            {
                "name": "Xiang Chen",
                "org": "Xiangya Hospital, Central South University, Changsha, China"
            },
            {
                "name": "Jingce Lei",
                "org": "Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA"
            },
            {
                "name": "Kan Ze",
                "org": "Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA"
            },
            {
                "name": "Liyun Dong",
                "org": "Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA"
            },
            {
                "name": "Xiangpeng Dai",
                "org": "Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA"
            },
            {
                "name": "Yang Gao",
                "org": "Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA"
            },
            {
                "name": "Daisheng Song",
                "org": "Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA"
            },
            {
                "name": "Brett L. Ecker",
                "org": "The Wistar Institute, Philadelphia, USA"
            },
            {
                "name": "Ruifeng Yang",
                "org": "Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA"
            },
            {
                "name": "Caitlin Feltcher",
                "org": "Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA"
            },
            {
                "name": "Kai Peng",
                "org": "Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA"
            },
            {
                "name": "Cheng Feng",
                "org": "Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA"
            },
            {
                "name": "Hui Chen",
                "org": "Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA"
            },
            {
                "name": "Rebecca X. Lee",
                "org": "Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA"
            },
            {
                "name": "Heddy Kerestes",
                "org": "Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA"
            },
            {
                "name": "Jingwen Niu",
                "org": "Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA"
            },
            {
                "name": "Suresh Kumar",
                "org": "Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA"
            },
            {
                "name": "Weiting Xu",
                "org": "Department of Computer Science, New Jersey Institute of Technology, Newark, USA"
            },
            {
                "name": "Jie Zhang",
                "org": "Department of Computer Science, New Jersey Institute of Technology, Newark, USA"
            },
            {
                "name": "Zhi Wei",
                "org": "Department of Computer Science, New Jersey Institute of Technology, Newark, USA"
            },
            {
                "name": "James S. Martin",
                "org": "Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA"
            },
            {
                "name": "Xiaoming Liu",
                "org": "Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA"
            },
            {
                "name": "Gordon Mills",
                "org": "Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, USA"
            },
            {
                "name": "Yiling Lu",
                "org": "Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, USA"
            },
            {
                "name": "Wei Guo",
                "org": "Department of Biology, School of Arts and Sciences, University of Pennsylvania, Philadelphia, USA"
            },
            {
                "name": "Lunquan Sun",
                "org": "Xiangya Hospital, Central South University, Changsha, China"
            },
            {
                "name": "Lin Zhang",
                "org": "Center for Research on Reproduction & Women’s Health, University of Pennsylvania, Philadelphia, USA"
            },
            {
                "name": "Ashani Weeraratna",
                "org": "The Wistar Institute, Philadelphia, USA"
            },
            {
                "name": "Meenhard Herlyn",
                "org": "The Wistar Institute, Philadelphia, USA"
            },
            {
                "name": "Wenyi Wei",
                "org": "Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA"
            },
            {
                "name": "Frank S. Lee",
                "org": "Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA"
            },
            {
                "name": "Xiaowei Xu",
                "org": "Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA"
            }
        ],
        "venue": "Nature Communications",
        "year": 2018
    },
    "we3j1mBA": {
        "id": "we3j1mBA",
        "title": "Deep learning for sequence pattern recognition.",
        "abstract": "Deep Learning is a superb way to solve remote sensing related problems, which mainly cover four perspectives: image processing, pixel-based classification, target recognition and scene understanding. In this paper, we focus on target recognition by building deep learning models, and our target is sequence pattern. Accurate prediction of sequence pattern would help identify significant characters from text sequence. Despite considerable advances in using machine learning techniques for sequence pattern recognition problem, its efficiency is still limited because of its involving extensive manual feature engineering in the process of features extraction from raw sequences. Thus, we apply a deep learning approach in sequence pattern recognition problem. The sequences of the datasets we used are self-generated genomic format sequences, and each dataset is generated based on a kind of pattern. We then investigate and construct various deep neural network models (such as convolutional networks, recurrent networks and a hybrid of convolutional and recurrent networks). The one-hot encoding method that preserves the vital position information of each character is presented to represent sequences as inputs to the models. The sequence patterns are then extracted from the input and output the probabilities of the existence of sequence patterns. Experimental results demonstrate that the deep learning approaches can achieve high accuracy and high precision in sequence pattern recognition. In addition, a saliency-map-based method is applied to visualize the learned sequence patterns. In view of the simulation results, we believe that we can find an appropriate deep learning model for a certain sequence sensing problem.",
        "keywords": "",
        "authors": [
            {
                "name": "Xin Gao",
                "org": "Department of Computer Science, New Jersey Institute of Technology, Newark, NJ, USA"
            },
            {
                "name": "Jie Zhang",
                "org": "Data Science, Adobe Systems Inc., San Jose, CA, USA"
            },
            {
                "name": "Zhi Wei",
                "org": "Department of Computer Science, New Jersey Institute of Technology, Newark, NJ, USA"
            }
        ],
        "venue": "ICNSC",
        "year": 2018
    },
    "vnvhyOhW": {
        "id": "vnvhyOhW",
        "title": "A Deep Learning Approach to Competing Risks Representation in Peer-to-Peer Lending.",
        "abstract": "Online peer-to-peer (P2P) lending is expected to benefit both investors and borrowers due to their low transaction cost and the elimination of expensive intermediaries. From the lenders' perspective, maximizing their return on investment is an ultimate goal during their decision-making procedure. In this paper, we explore and address a fundamental problem underlying such a goal: how to represent the two competing risks, charge-off and prepayment, in funded loans. We propose to model both potential risks simultaneously, which remains largely unexplored until now. We first develop a hierarchical grading framework to integrate two risks of loans both qualitatively and quantitatively. Afterward, we introduce an end-to-end deep learning approach to solve this problem by breaking it down into multiple binary classification subproblems that are amenable to both feature representation and risks learning. Particularly, we leverage deep neural networks to jointly solve these subtasks, which leads to the in-depth exploration of the interaction involved in these tasks. To the best of our knowledge, this is the first attempt to characterize competing risks for loans in P2P lending via deep neural networks. The comprehensive experiments on real-world loan data show that our methodology is able to achieve an appealing investment performance by modeling the competition within and between risks explicitly and properly. The feature analysis based on saliency maps provides useful insights into payment dynamics of loans for potential investors intuitively.",
        "keywords": [
            "Investment",
            "Neural networks",
            "Peer-to-peer computing",
            "Machine learning",
            "Loans and mortgages",
            "Data models",
            "Learning systems"
        ],
        "authors": [
            {
                "name": "Fei Tan",
                "org": "Department of Computer Science, New Jersey Institute of Technology, Newark, NJ, USA"
            },
            {
                "name": "Xiurui Hou",
                "org": "Department of Computer Science, New Jersey Institute of Technology, Newark, NJ 07102 USA."
            },
            {
                "name": "Jie Zhang",
                "org": "Adobe Systems, San Jose, CA 95110 USA."
            },
            {
                "name": "Zhi Wei",
                "org": "Department of Computer Science, New Jersey Institute of Technology, Newark, NJ, USA"
            },
            {
                "name": "Zhenyu Yan",
                "org": "Adobe Systems, San Jose, CA 95110 USA."
            }
        ],
        "venue": "IEEE transactions on neural networks and learning systems",
        "year": 2018
    },
    "dGXFJm8s": {
        "id": "dGXFJm8s",
        "title": "Structural and nitrogenation of Sm2Fe16.5Ti0.5 alloy prepared by HDDR process",
        "abstract": "Sm2Fe16.5Ti0.5Ny powder is synthesized by hydrogenation-disproportionation-desorption-recombination (HDDR) process and nitrogenation. As-cast Sm2Fe16.5Ti0.5 alloy behaves preferred direction, which is the 214 diffraction of Sm2(Fe, Ti)17. In the as-homogenized ingots, main phase Sm2(Fe, Ti)17 co-exists with only about 0.6% α-Fe(Ti). After treated by different cycles of HDDR process, the phase compositions aren't changed any more, but the content of α-Fe(Ti) is increased. Moreover, HDDR process contributes to the fine-grained microstructure and improves the coercivity. The nitrogenation process mainly includes two stages, one is fast reaction between N and Sm-Fe-Ti phase, another is lengthy homogenized diffusion of N. The content of Fe-rich phases is increased with increasing nitrogenation time. The lattice expansion of Sm2(Fe, Ti)17Ny nitrides is controlled by HDDR and nitrogenation processes together. The optimal coercivity of 164.9 kA/m is obtained at nitrogenation 2 h, and the excellent remanence of 45.7 Am2/kg is presented at nitrogenation 12 h.",
        "keywords": [
            "Hydrogenation-disproportionation-desorption-recombination",
            "Magnetic properties",
            "Nitrogenation",
            "Sm2Fe16.5Ti0.5",
            "Structural"
        ],
        "authors": [
            {
                "name": "Jibing Sun",
                "org": "Hebei University of Technology(Hebei University of Technology),Tianjin,China"
            },
            {
                "name": "Chunxiang Cui",
                "org": "Hebei University of Technology(Hebei University of Technology),Tianjin,China"
            },
            {
                "name": "Ying Zhang",
                "org": "Hebei University of Technology(Hebei University of Technology),Tianjin,China"
            },
            {
                "name": "Yuling Liu",
                "org": "Hebei University of Technology(Hebei University of Technology),Tianjin,China"
            },
            {
                "name": "Lin Li",
                "org": "Hebei University of Technology(Hebei University of Technology),Tianjin,China"
            },
            {
                "name": "Wei Yang",
                "org": "Hebei University of Technology(Hebei University of Technology),Tianjin,China"
            },
            {
                "name": "Ru Wang",
                "org": "Hebei University of Technology(Hebei University of Technology),Tianjin,China"
            }
        ],
        "venue": "Gongneng Cailiao/Journal of Functional Materials",
        "year": 2006
    },
    "BV2uFwHw": {
        "id": "BV2uFwHw",
        "title": "Structural and nitrogenation of Sm 2 Fe 16 Ti 1 alloy prepared by HDDR process",
        "abstract": "",
        "keywords": [
            "nitrogen",
            "magnetic properties",
            "structure",
            "grain boundary"
        ],
        "authors": [
            {
                "name": "jibing sun",
                "org": "hebei university of technology"
            },
            {
                "name": "chunxiang cui",
                "org": "hebei university of technology"
            },
            {
                "name": "ying zhang",
                "org": "hebei university of technology"
            },
            {
                "name": "ru wang",
                "org": "hebei university of technology"
            },
            {
                "name": "lin li",
                "org": "hebei university of technology"
            },
            {
                "name": "wei yang",
                "org": "hebei university of technology"
            },
            {
                "name": "yuling liu",
                "org": "hebei university of technology"
            }
        ],
        "venue": "Materials Chemistry and Physics",
        "year": 2006
    },
    "WmtQU6FQ": {
        "id": "WmtQU6FQ",
        "title": "Structural and nitrogenation of Sm2Fe16Ti 1 alloy prepared by HDDR process",
        "abstract": "Sm2Fe16Ti1Ny powder is synthesized by HDDR treatment and nitrogenation. As-cast Sm2Fe 16Ti1 alloy has a few preferred directions. The main phase of Sm3(Fe,Ti)29 and the secondary phases of SmFe11Ti, SmFe2 or Sm(Fe,Ti)2 as well as little α-Fe(Ti) coexist in as-cast alloy. In the as-homogenized ingot, the main phase Sm3(Fe,Ti)29 still co-exists with Fe 9.5SmTi1.5, SmFe11Ti and a few Sm-rich phases. When Sm2Fe16Ti1 alloy is treated by different cycles of HDDR process, the Sm2(Fe,Ti)17 main phase and a little α-Fe(Ti) present. Moreover, HDDR process contributes to the cracks of powder and grain boundaries. After the powder was nitrogenated for less than 12 h, the phase compositions are not changed any more, where the content of Fe-rich phases is increasing with respect to nitrogenation time. Moreover, the diffraction peaks of Fe-rich phases are little shifted to lower angle side. The nitrogenation process mainly includes two stages, one is fast reaction and diffusion between nitrogen atoms and Sm-Fe-Ti phases, the other is long-time homogenized diffusion of nitrogen. The optimal coercivity of 1859 Oe is obtained at nitriding 6 h, and the excellent magnetization of 126.4 emu g -1 and remanence of 48.3 emu g-1 are presented at nitriding 12 h. © 2005 Elsevier B.V. All rights reserved.",
        "keywords": [
            "HDDR",
            "Magnetic properties",
            "Sm2Fe16Ti1Ny",
            "Structure"
        ],
        "authors": [
            {
                "name": "Jibing Sun",
                "org": "Hebei University of Technology(Hebei University of Technology),Tianjin,China"
            },
            {
                "name": "Chunxiang Cui",
                "org": "Hebei University of Technology(Hebei University of Technology),Tianjin,China"
            },
            {
                "name": "Ying Zhang",
                "org": "Hebei University of Technology(Hebei University of Technology),Tianjin,China"
            },
            {
                "name": "Ru Wang",
                "org": "Hebei University of Technology(Hebei University of Technology),Tianjin,China"
            },
            {
                "name": "Lin Li",
                "org": "Hebei University of Technology(Hebei University of Technology),Tianjin,China"
            },
            {
                "name": "Wei Yang",
                "org": "Hebei University of Technology(Hebei University of Technology),Tianjin,China"
            },
            {
                "name": "Yuling Liu",
                "org": "Hebei University of Technology(Hebei University of Technology),Tianjin,China"
            }
        ],
        "venue": "Materials Chemistry and Physics",
        "year": 2006
    },
    "t1qOiJZ7": {
        "id": "t1qOiJZ7",
        "title": "Structural and nitrogenation of Sm2Fe16Ti1 alloy prepared by HDDR process",
        "abstract": "Sm 2 Fe 16 Ti 1 N y powder is synthesized by HDDR treatment and nitrogenation. As-cast Sm 2 Fe 16 Ti 1 alloy has a few preferred directions. The main phase of Sm 3 (Fe,Ti) 29 and the secondary phases of SmFe 11 Ti, SmFe 2 or Sm(Fe,Ti) 2 as well as little α-Fe(Ti) coexist in as-cast alloy. In the as-homogenized ingot, the main phase Sm 3 (Fe,Ti) 29 still co-exists with Fe 9.5 SmTi 1.5 , SmFe 11 Ti and a few Sm-rich phases. When Sm 2 Fe 16 Ti 1 alloy is treated by different cycles of HDDR process, the Sm 2 (Fe,Ti) 17 main phase and a little α-Fe(Ti) present. Moreover, HDDR process contributes to the cracks of powder and grain boundaries. After the powder was nitrogenated for less than 12 h, the phase compositions are not changed any more, where the content of Fe-rich phases is increasing with respect to nitrogenation time. Moreover, the diffraction peaks of Fe-rich phases are little shifted to lower angle side. The nitrogenation process mainly includes two stages, one is fast reaction and diffusion between nitrogen atoms and Sm–Fe–Ti phases, the other is long-time homogenized diffusion of nitrogen. The optimal coercivity of 1859 Oe is obtained at nitriding 6 h, and the excellent magnetization of 126.4 emu g −1 and remanence of 48.3 emu g −1 are presented at nitriding 12 h. Keywords Sm 2 Fe 16 Ti 1 N y HDDR Structure Magnetic properties 1 Introduction Since the discovery of Sm 2 Fe 17 N y interstitial compounds [1] , this hard magnetic material has attracted the interests of many researchers for its unique magnetic characteristics [1–2] . Subsequently, SmFe 11 TiN y compounds with ThMn 12 -type structure (1:12) were discovered by Yang et al. [3] in 1991. The latest series of rare-earth transition metal nitrides are based on monoclinic R 3 Fe 29− x M x structure (M = Ti, V, Cr, Mo, Mn), which previously identified by Collocott et al. in 1992 as R 2 (Fe,Ti) 19 [4] . Like the 2:17 and 1:12 type compounds, the 3:29 series represent a variation of the CaCu 5 -type structure, in which a fraction of R atoms are replaced by transition metal dumbbell pairs. There are two large interstitial octahedral sites on which N atoms can locate, leading to a maximum N concentration of four atoms per formula unit, which also leads to a volume expansion of about 6%. There is a considerable uncertainty in the literature about the anisotropy field, stability and so on of 3:29 compounds [5–10] . The three types of compounds above have been found to have suitable magnetic properties for permanent magnet applications [1–19] . These Sm–Fe–M-type compounds have been produced by several techniques, including conventional powder broken method [1–4,7,11] , mechanically alloying [12–13] , rapid solidification [14] and hydrogen treatment [15–19] . Moreover, the fine-grained microstructure can be obtained by the reaction of Sm–Fe and hydrogen in the hydrogenation–disproportionation–desorption–recombination (HDDR) process [15,18] , and the intrinsic magnetic properties such as coercivity can be improved. Actually, like 1:12-type compound, the binary compound R 3 Fe 29 is metastable [8] . However, if a certain amount of ternary elements M (M = Cr, Mo, V, Ti, Nb) is added, R 3 (Fe, M) 29 becomes stable [4–5,10,17] . So it is interesting to study further the structures and magnetic properties of these compounds in detail. We have found that the higher fraction of 3:29 phase is easier to be prepared when the Ti content approaches to one atom per Sm 2 Fe 17 formula unit. Up to now, the HDDR process and nitrogenation of 3:29-type phase are little studied in detail. So in this paper, the phase formation, microstructures, nitrogenation and magnetic properties of Sm 2 Fe 16 Ti 1 alloy and its nitrides were investigated. 2 Experimental details Sm 2 Fe 16 Ti 1 parent alloy was prepared by arc melting under a purified argon atmosphere. The purities of Sm, Fe and Ti were higher than 99.95%. Extra 25% Sm was added to compensate the loss of Sm due to the evaporation. The ingots were annealed at 1000 °C for 48 h under a pure argon atmosphere and water quenched after annealing. The annealed ingots were crushed into powder with the size of 3–5 mm. The coarse particles were hydrogenated at 800 °C for 2 h in a high purity hydrogen atmosphere of 0.12 MPa. Subsequently, the hydrogenated particles were degassed at 800 °C for 2 h. When the pressure in the stove was lower than 3 × 10 −3 Pa and the temperature dropped to room temperature, one cycle of HDDR process was finished. The HDDR-treated powder was crushed to less than 38 μm. In the end, the powder was nitrogenated at 500 °C for different time in a pure initial nitrogen atmosphere of 0.13 MPa. The nitrogen content was measured by mass analysis with electronic balance at the precision of 10 −4 g. X-ray diffraction (Philips X’pert MPD) data were obtained by using Cu Kα radiation to determine the crystal structure. A standard least square fit refinement routine was used to derive the lattice parameters using X-ray diffraction data. Scanning electron microscopy (Philips XL30W/TMP SEM) was used to observe the microstructure and analyses the micro-zone. Magnetic properties were measured using the vibrating sample magnetometer (Lakeshore 7407 model VSM) with the maximum magnetic field of 10 000 Oe. The results of the VSM measurement were not revised because it is difficult to determine a demagnetizatin factor for the powder in this study. 3 Results and discussion The XRD patterns of as-cast and annealed Sm 2 Fe 16 Ti 1 alloys are shown in Fig. 1 . It is found that there are a few preferred directions in as-cast alloys, and the phases of ingots perpendicular to cooling direction ( Fig. 1 (a)) are composed of Sm 3 (Fe,Ti) 29 with monoclinic Nd 3 (Fe,Ti) 29 -type structure (3:29), SmFe 11 Ti with tetragonal ThMn 12 -type structure (1:12), Sm(Fe,Ti) 2 with hexagonal structure (1:2) and little α-Fe(Ti) phases. When the ingots are quickly cooled parallel to cooling direction ( Fig. 1 (b)), the phase compositions are similar to Fig. 1 (a). The differences in Fig. 1 (b) can be summed up into two points: first, the Sm-rich phase is not Sm(Fe,Ti) 2 but SmFe 2 ; second, the content of 3:29-type phase is higher than that in Fig. 1 (a). After the annealed ingots are quickly cooled with water, the phase compositions consist of Sm 3 (Fe,Ti) 29 , SmFe 11 Ti, Fe 9.5 SmTi 1.5 and little Sm-rich phase of Sm(Fe,Ti) 2 . The content of 3:29-type phase is increased, while a new 1:11-type phase, Fe 9.5 SmTi 1.5 with tetragonal Sm(Fe,Ti) 11 -type structure, is observed. It should be emphasized that the content of α-Fe is little in both as-cast and annealed alloys. Fig. 2 shows the BSE images of as-cast and annealed Sm 2 Fe 16 Ti 1 alloys. We can see from Fig. 2 (a) that the white phase distributed in the boundaries is Sm(Fe,Ti) 2 , where the gray matrix is Sm 3 (Fe,Ti) 29 , and the black block phases are some SmFe 11 Ti and a little α-Fe(Ti). In annealed alloy, the gray matrix still corresponds to Sm 3 (Fe,Ti) 29 . The small black blocks are SmFe 11 Ti and Fe 9.5 SmTi 1.5 , and the white spots are the remnant Sm-rich 1:2-type phases. The annealed ingots were crushed into particles with the size of 3–5 mm. The coarse particles were hydrogenated at 800 °C for 2 h in a high purity hydrogen atmosphere of 0.12 MPa, and then degassed at 800 °C for 2 h. In the end, they continued to be degassed until the pressure in the stove was less than 3 × 10 −3 Pa and the temperature dropped to room temperature to finish one cycle of HDDR process. It is found that however the particles are treated by two cycles of HDDR ( Fig. 3 (b) ) or by four cycles of HDDR ( Fig. 3 (c)), the Sm 2 Fe 16 Ti 1 alloy is composed of Sm 2 (Fe,Ti) 17 main phase with rhombohedral Th 2 Zn 17 -type structure and α-Fe. Furthermore, the content of α-Fe is increased from 4.9% in volume percent by two cycles of HDDR to 6.6% by four cycles of HDDR. This also means that the hydrogen has thoroughly destroyed the structures of Sm 3 (Fe,Ti) 29 , SmFe 11 Ti and Fe 9.5 SmTi 1.5 . We [15] have known that the hydrogenation –disproportionation–desorption–recombination (HDDR) processes of Sm 2 Fe 17 -type alloys were carried out as the following reactions (1)–(3) : (1) Sm 2 Fe 17 + H 2 → Sm 2 Fe 17 H y , (2) Sm 2 Fe 17 H y + H 2 → SmH y + α-Fe, (3) SmH y + α-Fe → Sm 2 Fe 17 + H 2 . So we can deduce that for Sm 2 Fe 16 Ti 1 alloy, the first reaction mechanism in hydrogen atmosphere is still hydrogenation–disproportionation, which follow the reactions (4)–(6) . As Zhao et al. [18,8] described, 3:29-type phase is metastable, and the following structure relationship is valid: Sm 3 (Fe,Ti) 29 = Sm 2 Fe 17 + SmFe 11 Ti. The SmFe 11 Ti is also metastable. The hydrogen atom is small enough to enter easily the interstitial sites of Sm–Fe–Ti phases, and the lattice stress accumulated by hydrogen can be high enough to decompose all metastable structures and form SmH y and α-Fe phases: (4) Sm 3 (Fe,Ti) 29 + H 2 → Sm 3 (Fe,Ti) 29 H y + H 2 → SmH y + α-Fe(Ti), (5) SmFe 11 Ti + H 2 → SmFe 11 TiH y + H 2 → SmH y + α-Fe(Ti), (6) Fe 9.5 SmTi 1.5 + H 2 → Fe 9.5 SmTi 1.5 H y + H 2 → SmH y + α-Fe(Ti). When the particles are degassed by means of pumping vacuum process, the desorption–recombination process is reacted as the following reaction (7) , and the HDDR cycle is finished: (7) SmH y + α-Fe(Ti) → Sm 2 (Fe,Ti) 17 + H 2 . The lattice stress accumulated by hydrogen is high enough not only to destroy the structures of Sm–Fe–Ti phases but also to smash the particles as shown in Fig. 4 (a) and to crack the grain boundries as shown in Fig. 4 (b). So the HDDR-treated particles are easier to crush to finer powder. Fig. 5 shows the XRD patterns of Sm 2 Fe 16 Ti 1 alloy nitrogenated for 0–12 h after HDDR. The main phase of nitrogenaed alloy is Sm 2 (Fe,Ti) 17 N y , and its diffraction peaks sites are all shifted to the lower angle sides of those of Sm 2 Fe 17 N 3 phase. For instance, the lattice parameters of 2:17-type phase in Sm 2 Fe 16 Ti 1 N y alloy nitrogenated for 2 h are a = 8.75 Å, c = 12.64 Å, V = 838.13 Å 3 , and nitrogenated for 12 h are a = 8.77 Å, c = 12.75 Å, V = 848.85 Å 3 , while the lattice parameters of Sm 2 Fe 17 N 3 phase are a = 8.74 Å, c = 12.66 Å, V = 837.50 Å 3 . If taking account of the effect of the expansion of Ti substitution for Fe, the y values of nitrogen content in Sm 2 Fe 17 N y phase is close to or more than 3. In addition, compared with the diffraction peaks of Sm 2 (Fe,Ti) 17 phase after HDDR in Fig. 5 (a), the diffraction sites of Sm 2 (Fe,Ti) 17 N y phase nitrogenated only for 2 h have greatly shifted to the lower angle side. With increasing the nitrogenation time again, the shifting to lower angle becomes unobvious, which is highly consistent with the nitrogen content dependence on the nitrogenation time in Fig. 6 . So the nitrogenation of these alloy powder is controlled by two steps: in the initial nitrogenation stage, the rate of solution and reaction of nitrogen atoms with Sm 2 (Fe,Ti) 17 phase is faster, but 1 or 2 h later, the diffusion of nitrogen in Sm 2 (Fe,Ti) 17 N y phase is the predominant behavior, so the nitrogenation rate becomes slower. The secondary phases consist of more α-Fe and less Fe 2 Ti in nitrides. The diffraction peaks of Fe-rich phase are little shifted to lower angle sides as shown in Fig. 5.2. But with increasing the nitrogenation time, the content of α-Fe is increased from 5.3% for 2 h to 6.3%, 9.6%, 10.7% for 6 h, 9 h, 12 h, respectively. The dependence of magnetic properties of nitride powder on the nitrogenation time is presented in Fig. 7 . The magnetic properties of nitrides are obviously better than those of Sm–Fe–Ti alloy. Furthermore, the magnetic properties of the powder are increased quickly before nitrogenated for 2 h, which is corresponding to the nitrogen content of 2.77% in Fig. 6 , namely, the y value of Sm 2 (Fe,Ti) 17 N y phase is less than 3. When nitrogenated for 6 h and the nitrogen content amounts to 3.60%, the nitride behaves with the best coercivity of 1859 Oe. When nitrogenation time increases to 9 h, the coercivity of nitride is rapidly decreased to 1333.7 Oe corresponding to nitrogen content of 3.91%. The coercivity again increased to 1529.2 Oe corresponding to the nitrogen content of 4.26% after nitrogenated for 12 h. These nitrogen contents are higher than that of Sm 2 Fe 17 N 3 phase. This can be attributed to two reasons: first, the radius of Ti atom is bigger than that of Fe atom; second, H atoms have enlarged and destroyed the smaller interstitial sites. It is well known that the introduced nitrogen atoms occupy the 9e octahedral sites and/or smaller 18g tetragonal sites in the Th 2 Zn 17 -type structure. The ideal N content of 3 per formula Sm 2 Fe 17 N 3 corresponds to completely filling the 9e sites, and little N can enter to the 18g sites [6] . But H atoms can easily enter not only the 9e sites but also the 18g sites and form Sm 2 Fe 17 H 5 [19] . In our study, because of the role of Ti and H, partial N atoms can fill both 9e and 18g sites, therefore the nitrogen content in Sm 2 Fe 16 Ti 1 N y is higher. Moreover, HDDR process is beneficial to the finer powder, which also promotes the coercivity. But when the nitrogen content is high enough to change the Fe–Fe interatomic distances at the Fe sites (18h and 18f as well as 6c and 9d) [2] , the magnetic properties will also be worsened such as the coercivity of nitriding for 9 h. As mentioned above, the stress in Sm 2 (Fe,Ti) 17 N y phase is highly accumulated. In order to make it stable, the Fe(Ti) atoms may be released or excluded from 2:17-type phase by N atoms with smaller size in diameter, which will lead to increasing the content of Fe-rich phases consisted of α-Fe and Fe 2 Ti. This is the main reason that the magnetization is continuous to improve with increasing nitrogenation time. The remanence is affected by coercivity and magnetization together, which reaches the minimum value at 9 h and the maximum value at 12 h. It should be noticed that when nitrogenated for 12 h, the Sm 2 Fe 16 Ti 1 N y alloy powder behaves the higher coercivity of 1529.2 Oe, the highest magnetization of 126.4 emu g −1 and remanence of 48.3 emu g −1 , which is the characteristics of Sm 2 (Fe,Ti) 17 N y phase fully nitrogenated and stabilized. 4 Conclusions The phase formation, nitrogenation and magnetic properties of Sm 2 Fe 16 Ti 1 alloy and its nitride were investigated by HDDR treatment and nitrogenation. We found the larger fraction of Sm 3 (Fe,Ti) 29 -type phase in as-cast and homogenized alloys can only be obtained when Ti content amounts to one atom per Sm 2 Fe 16 Ti 1 formula. However, 3:29-type structure is metastable and easy to be destroyed by hydrogen. In addition, in the as-homogenized ingot, small fraction of metastable phase, Fe 9.5 SmTi 1.5 , was found. When Sm 2 Fe 16 Ti 1 alloy was treated by different cycles of HDDR process, main phase Sm 2 (Fe,Ti) 17 and a little α-Fe(Ti) were presented. Moreover, HDDR process contributed to the cracks of powder and grain boundaries. When the powder was nitrogenated for less than 12 h, the phase compositions were not changing any more, but the content of Fe-rich phases was increased with increasing nitrogenation time. And the diffraction peaks of Fe-rich phases were slightly shifted to lower angle sides. The nitrogenation process could be summed up into two stages: one was fast reaction diffusion of N and Sm–Fe–Ti alloy; the other was lengthy homogenized diffusion of nitrogen. The optimal coercivity of 1859 Oe was obtained when nitriding for 6 h, and the excellent magnetization of 126.4 emu g −1 and remanence of 48.3 emu g −1 were presented when nitriding for 12 h. So whether the 3:29-type phase can be prepared after HDDR and nitrogenation should still be studied by changing the techniques in the near future. Acknowledgments This work was supported in part by the National Natural Sciences Foundation of China under Grant No. 50271024 and National Natural Science Foundation of Hebei Provience of China under Grant No. 501013. References [1] J.M.D. Coey H. Sun J. Magn. Magn. Mater. 87 1990 L251 [2] K. Kobayashi M. Ohmura Y. Yoshida M. Sagawa J. Magn. Magn. Mater. 247 2002 42 [3] Y.C. Yang X.D. Zhang L.S. Kong Appl. Phys. Lett. 58 1991 2042 [4] S.J. Collocott R.K. Day J.B. Dunlop R.L. Davis Proceedings of the Seventh International Symposium on Magnetic Anisotropy and Coercivity in RE–TM alloys Canberra, July 1992 437 [5] H.-W. Kwon J. Alloys Compd. 327 2001 206 [6] J.M.D. Coey P.A.I. Smith J. Magn. Magn. Mater. 200 1999 405 [7] D. Courtois H.-S. Li J.M. Cadogan Pergamon Solid State Commun. 98 1996 565 [8] A. Paoluzi L. Pareti F. Albertini M.R. Ibarra L. Morellon B.-p. Hu Y.Z. Wang D. Courtois J. Magn. Magn. Mater. 196–197 1999 840 [9] L.Z. Cao J. Shen N.X. Chen J. Alloys Compd. 336 2002 18 [10] W.Q. Wang J.L. Wang W.X. Li J. Alloys Compd. 358 2003 12 [11] I. Mikio M. Kazuhiko S. Toru J. Alloy Compd. 349 2003 334 [12] I. Nehdi L. Bessais C. Djega-Mariadassou J. Alloys Compd. 351 2003 24 [13] W. Kaszuwara M. Leonowicz J.A. Kozubowski Mater. Lett. 42 2000 383 [14] J.E. Shield J. Alloys Compd. 291 1999 222 [15] J.B. Sun C.X. Cui Y. Zhang R. Wang R.G. Wu Z.M. Liang Chin. J. Nonferrous Met. 14 2004 1590 [16] N.X. Chen S.Q. Hao Y. Wu J. Magn. Magn. Mater. 233 2001 169 [17] X.F. Han R.G. Xu X.H. Wang H.G. Pan E. Baggio-Saitovitch T. Miyazaki F.M. Yang C.P. Chen J. Magn. Magn. Mater. 190 1998 257 [18] X.G. Zhao Z.D. Zhang X.K. Sun W. Liu Z.J. Guo Q.F. Xiao D.Y. Geng J. Magn. Magn. Mater. 208 2000 231 [19] M. Zinkevich N. Mattern A. Handstein J. Alloys Compd. 339 2002 118",
        "keywords": [],
        "authors": [
            {
                "name": "Ji-Bing Sun",
                "org": "Postdoctoral Programme, School of Information and Engineering, Hebei University of Technology, Tianjin 300130, PR China"
            },
            {
                "name": "Chun-Xiang Cui",
                "org": ""
            },
            {
                "name": "Ying Zhang",
                "org": "School of Material Science and Engineering, Hebei University of Technology, Tianjin 300130, PR China"
            },
            {
                "name": "Ru Wang",
                "org": "School of Material Science and Engineering, Hebei University of Technology, Tianjin 300130, PR China"
            },
            {
                "name": "Lin Li",
                "org": "School of Material Science and Engineering, Hebei University of Technology, Tianjin 300130, PR China"
            },
            {
                "name": "Wei Yang",
                "org": "School of Material Science and Engineering, Hebei University of Technology, Tianjin 300130, PR China"
            },
            {
                "name": "Yu-Ling Liu",
                "org": "Postdoctoral Programme, School of Information and Engineering, Hebei University of Technology, Tianjin 300130, PR China"
            }
        ],
        "venue": "Materials Chemistry and Physics",
        "year": 2006
    },
    "FWbaEuyD": {
        "id": "FWbaEuyD",
        "title": "Simulation of Fracture of Nanocrystalline Metals",
        "abstract": "",
        "keywords": [
            "damage",
            "ductitility",
            "fracture",
            "grain boundary",
            "nanocrystalline metals",
            "ductility"
        ],
        "authors": [
            {
                "name": "Fan Yang",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            }
        ],
        "venue": "Advanced Materials Research",
        "year": 2008
    },
    "arJ5BsLa": {
        "id": "arJ5BsLa",
        "title": "Effects of quenching speeds on microstructure and magnetic properties of novel SmCo6.9Hf0.1(CNTs)0.05 melt-spun ribbons",
        "abstract": "By adding carbon nanotubes (CNTs) to SmCo 6.9 Hf 0.1 , novel SmCo 6.9 Hf 0.1 (CNTs) 0.05 as-cast alloy has been prepared, which consists of Sm(Co,Hf) 7 as the main phase, a small amount of SmCo 5 and a particle-like grain boundary phase Hf(CNTs). SmCo 6.9 Hf 0.1 (CNTs) 0.05 ribbons melt-spun at speeds of 10–50 m s −1 have a single TbCu 7 -type structure. Increasing the quenching speed can result in a decrease in ribbon thickness and grain boundary width. Meanwhile, the grain size tends to be smaller and the grain boundary phase tends to be more dispersed. A new Sm(Co,Hf) 7 (CNTs) x boundary phase may be formed in SmCo 6.9 Hf 0.1 (CNTs) 0.05 ribbons. Increasing the quenching speed can also enhance coercivity, remanence and remanence ratio. The ribbons melt-spun at a speed of 50 m s −1 display the best magnetic properties: H ci = 18.781 kOe, M s2T = 76.87 emu g −1 , M r = 66.79 emu g −1 and M r / M s2T = 0.87. Keywords Melt spinning Intermetallic compounds Crystal structure Microstructure Magnetic properties 1 Introduction The trend in both military and commercial markets for greater affordability has prompted electromechanical designers to look towards devices that work at higher speeds and higher operating temperatures. New magnetic materials are essential for the success of many of these power generation, distribution and utilization systems [1] . Among the existing high-performance rare earth permanent magnets, only Sm–Co matrix magnets can work at over 400 °C. Most high-temperature permanent magnets are Sm 2 Co 17 –SmCo 5 two-phase magnets characterized by a cellular microstructure and pinning-controlled coercivity. In optimized magnets, coercivity up to 10 kOe has been obtained at 500 °C [2] . Recently, interest has been focused on Sm(Co,M) 7 (M = stabilizing element) compounds with the TbCu 7 -type structure (space group P 6/ mmm ) due to their potential applications as novel high-temperature rare earth permanent magnets. Since the composition of SmCo 7 lies between that of SmCo 5 and Sm 2 Co 17 , this kind of compound may retain reasonably high moment and anisotropy. However, pure SmCo 7 phase is unstable, so a third element, e.g. Si, Cu, Nb or Hf, is necessary to stabilize the TbCu 7 -type Sm–Co 1:7H phase and to improve its magnetic properties. Guo and co-workers [3–7] directly prepared some Sm–Co 1:7H intermetallic compounds by arc melting. Among those third metallic elements, Hf had been reported as the most effective element both in stabilizing the TbCu 7 -type structure and in enhancing its magnetocrystalline anisotropy field; furthermore, Sm(Co,Hf) 7 alloy possesses high magnetization. Aich et al. [8] reported that the structure of SmCo 7 could be changed by adding Nb or C. They concluded Nb could stabilize the TbCu 7 -type structure and tended to reduce the amount of long-range order Sm 2 Co 17 , while C could reduce the scale of the microstructure and form an intergranular phase that effectively isolated the hard magnetic SmCo 7 grains from each other. The alloy ribbons melt-spun at 40 m s −1 had a maximum coercivity of 9 kOe when annealed at 800 °C, but heat treatment led to the precipitation of NbC. Zhang et al. [9] prepared bulk nanocrystalline SmCo 6.6 Nb 0.4 sintered magnet with the TbCu 7 -type structure by the spark plasma sintering (SPS) technique. The magnet exhibited good thermal stability while retaining a high coercivity of 0.48 T at 500 °C, and its coercivity temperature coefficient β is −0.169% K −1 . Chang et al. [10] prepared SmCo 7− x Hf x C y ribbons with the TbCu 7 -type structure from ingots with a wheel speed of 40 m s −1 . They found a slight C addition was helpful in refining the grain size of ribbons, and the maximum coercivity of 11.8 kOe was obtained after the addition of C. A small amount of face-centered cubic Co phase and Sm 2 Co 17 phase existed in C-containing ribbons, and a slight nonmagnetic Sm 2 C 3 phase for a higher C addition of y = 0.14 was present. Therefore, it is obvious that C addition in Sm(Co,M) 7 alloys is effective in refining the grain size and pinning the domain walls. On the other hand, the formation of nonmagnetic adnascent phase is inevitable. Carbon nanotubes (CNTs) are one-dimensional nanomaterials with a hexcirclic structure, which closely resembles the hexagonal structure of Sm(Co,M) 7 . CNTs are characterized by several excellent properties, such as good thermal conductivity (∼6000 W m −1 K −1 ), vacuum stability (2800 °C), adsorbability and inertness, which make them potentially an ideal component of a pinning phase. Recently, we prepared SmCo 7 , SmCo 6.9 Hf 0.1 , SmCo 6.9 Hf 0.1 (CNTs) 0.05 and SmCo 6.9 Hf 0.1 (CNTs) 0.1 melt-spun ribbons at a speed of 40 m s −1 . CNTs do not melt or enter into the 1:7 phase as interstitial atoms, but rather distribute regularly and uniformly in ribbons and as-cast alloys by means of the combination with Hf and Sm–Co. Pure SmCo 7 ribbons display the worst magnetic properties. After the addition of Hf into pure Sm–Co ribbons, the nominal composition changes into SmCo 6.9 Hf 0.1 and the coercivity ( H ci ) increases from 2.657 to 3.941 kOe, while remanence ( M r ), maximum magnetization ( M s2T , the magnetization measured under a field of 20 kOe) and remanence ratio ( M r / M s2T ) increase from 17.24 emu g −1 , 56.37 emu g −1 and 0.31 to 27.68 emu g −1 , 62.97 emu g −1 and 0.44, respectively. Adding extra CNTs to the ribbons with Hf can enhance the magnetic properties more significantly. The comprehensive magnetic properties of SmCo 6.9 Hf 0.1 (CNTs) 0.05 ribbons are H ci = 13.954 kOe, M r = 48.85 emu g −1 , M s2T = 61.09 emu g −1 , and M r / M s2T = 0.80. More importantly, we found cooling rate to be the key factor for forming the TbCu 7 -type phase in the ribbons. Therefore in this paper the effects of CNTs and rapid quenching speed on the phase structure and magnetic properties of SmCo 6.9 Hf 0.1 (CNTs) 0.05 alloys were studied. 2 Materials and methods The multiwall CNTs (MWCNTs) used in this study, which were prepared by chemical vapor deposition, were purchased from a commercial supplier. Their characteristics are as follows: inner diameter 5–10 nm, external diameter 25–70 nm, and length of several micrometers to tens of micrometers. More detailed parameters can also be seen in Ref. [11] . The alloy with nominal composition SmCo 6.9 Hf 0.1 (CNTs) 0.05 was made from high-purity (99.99%) elements and CNTs by arc melting in a high-purity argon atmosphere. Before arc melting, 8% extra Sm was added to the sample to compensate for the weight loss due to Sm vaporization during the process. The ingots were then rapidly solidified by melt spinning in high-purity argon at a chamber pressure of 0.6 × 10 5 Pa and a molybdenum wheel velocity of 10–50 m s −1 . The ribbon thickness was determined with a TT260 coating-thickness gauge. X-ray diffraction (XRD) analysis of the samples was performed with a Rigaku Dmax 2500 Pc X-ray diffractometer with Cu Kα radiation and a graphite monochromator. The microstructures were observed by scanning electron microscopy (SEM, Philips XL30w/TMP) and transmission electron microscopy (TEM, Philips Tecnai F20). The magnetic measurements were made with a Lake Shore 7407 vibrating sample magnetometer (VSM) with a maximum field of 20 kOe. All ribbon samples were magnetized by a 50 kOe pulse magnetic field prior to the VSM measurement. 3 Results and discussion 3.1 Phase structure Fig. 1 shows the XRD patterns of SmCo 6.9 Hf 0.1 (CNTs) 0.05 as-cast alloy and ribbons melt-spun at different speeds. It has been shown that the main phase of SmCo 6.9 Hf 0.1 (CNTs) 0.05 as-cast alloy is TbCu 7 -type Sm(Co,Hf) 7 (see Fig. 1 a and its local amplification a2). A small amount of SmCo 5 may exist because there is no separation between (2 0 0) and (1 1 1) diffraction peaks. It should be noted that a small amount of HfC new phase is formed in the alloy. In addition, the diffraction peaks of pure CNTs are not found, indicating that CNTs are mainly combined with Hf to form primitive hexagonal Hf(CNTs), which shares the same structure with HfC. The electronegativities of C, Co, Sm and Hf are 2.50, 1.70, 1.07 and 1.23, respectively [6] . The elements with larger electronegativity difference prefer to combine together, thus the affinities for forming ionic bonds, from big to small, are Sm–C, Hf–C, Hf–Co and Hf–Sm. However, no Sm–C compounds are found in SmCo 6.9 Hf 0.1 (CNTs) 0.05 alloy, which is different from the results of Chang et al. [10] , who reported that Sm 2 C 3 is formed in Sm–Co–Hf–C alloy. The reason for this discrepancy may be the CNTs that are used in this work, while Chang et al.’s work involved adding C to the alloy. It may also be because the chemical affinity of Hf(CNTs) is higher than that of Sm(CNTs). When the SmCo 6.9 Hf 0.1 (CNTs) 0.05 as-cast alloy is melt-spun at speeds of 10–50 m s −1 , only TbCu 7 -type phases are formed in the ribbon powders, and no SmCo 5 and Hf(CNTs) phases are found. Reutzel et al. [12] reported that if the undercooling of Sm–Co matrix alloys with proper chemical composition approaches 10 3 –10 5 K s −1 , the TbCu 7 structure can be formed. With the increase in melt-spun speed from 10 to 50 m s −1 , the undercooling increases, causing a reduction in ribbon thickness from 80 to 40 μm. As a result, the TbCu 7 structure is stabilized and the formation of SmCo 5 and Hf(CNTs) phases is suppressed. Even if the speed reaches 50 m s −1 , all the diffraction peaks are sharp despite a slight tendency to broaden, indicating that alloys do not contain any large amounts of amorphous phase. No CNTs or CNT-containing phases are found in Fig. 1 , and the distribution of such phases also remains unknown. 3.2 Microstructure Fig. 2 shows the line scanning image and results of SmCo 6.9 Hf 0.1 (CNTs) 0.05 as-cast alloys. Sm and Co are uniformly distributed on grain boundaries and throughout the grain interior. The high peaks of Hf and C show incomplete coincidence, which may be related to the imprecise measurement of C content. It should be emphasized that Hf and CNTs are both discontinuously distributed on grain boundaries, which correspond to the white bright grain boundary phase shown in Fig. 2 a and the Hf(CNTs) phase in Fig. 1 a. The black grains represent Sm(Co,Hf) 7 main phase and a small amount of SmCo 5 . Fig. 3 shows TEM images of SmCo 6.9 Hf 0.1 (CNTs) 0.05 ribbons melt-spun at speeds of 20–50 m s −1 . The grain boundaries of the ribbons melt-spun at different speeds display different morphologies. At 20 m s −1 ( Fig. 3 a), the grain boundary phase tends to accumulate. Selected-area electron diffraction (SAED) shows only 1:7H-type single-crystal electron diffraction patterns. The size of most grains exceeds the range of 400–600 nm, and the inset shows the SAED of Sm(Co,Hf) 7 grain with zone axis [ u v w = 1 1 ¯ 1 ¯ ] . As is well known, C content cannot be accurately investigated by energy-dispersive spectroscopy (EDS), so the composition of the ribbon cannot be precisely determined. However, EDS can still be used to qualitatively determine the compositions of grain boundaries and internal grains. The results show that the grain boundary is composed of Sm–Co–Hf–C, whereas in the inner grains, C element is barely found. As shown in Fig. 1 , only TbCu 7 -type phases are formed in all ribbons melt-spun at different speeds, and CNTs do not enter into the grains during the melt-spinning process, leading to the assumption that CNTs also participate in forming the TbCu 7 -type boundary phase, which may be interpreted as Sm(Co,Hf) 7 (CNTs) x . When the quenching speed reaches 30 m s −1 (see Fig. 3 b), there is still a high content of the grain boundary phase, and the grain size is also considerable. Meanwhile, only the 1:7H structure is found in the area observed, and the inset also shows the SAED pattern of grains with zone axis [ u v w = 1 1 ¯ 1 ¯ ] . As the quenching speed approaches 40 m s −1 (see Fig. 3 c), the grains maintain the same structure. The inset shows the SAED pattern of grains with zone axis [ u v w = 1 ¯ 0 1 ] . The grain size tends to decrease, and the grain boundary phase, which appears as “wheatear” or “discontinuous small particles” (see Fig. 3 d), tends to become slightly dispersed. However, it is still accumulated on part of the grain boundaries, and the maximum width of the grain boundary is approximately 200 nm. When the melt-spinning speed reaches 50 m s −1 (see Fig. 3 e), the grains still keep the TbCu 7 structure despite a significant change in morphology. The inset shows the SAED pattern of grains with zone axis [ u v w = 2 1 ¯ 1 ¯ ] . The grain size decreased markedly, with a minimum size of less than 200 nm. The grain boundaries, which are less than 100 nm in width, become smoother, with no obvious evidence of discontinuous small grains. The magnified image reveals the existence of a CNT-like grain boundary phase about 50 nm wide (see Fig. 3 f), corresponding to the black area of the grain boundary in Fig. 3 e. However, the ribbons display considerable remanence, causing unclear focus of the electron beam, so the corresponding high-resolution image cannot be observed. In conclusion, CNTs are undoubtedly distributed along the grain boundaries. The cooling rate of the alloys increases with the quenching speed, resulting in an increase in undercooling and a decrease in grain size. However, if the quenching speed is below 40 m s −1 , grain refinement is not obvious, whereas at a speed faster than 50 m s −1 , grain size can be suppressed significantly, and the area of grain boundaries can evidently increase. Meanwhile, the distribution of the CNT phase on grain boundaries would become more dispersed, and the size of grain boundaries would decrease to as small as a single CNT. Based on the above analysis, a microstructure model of melt-spun SmCo 6.9 Hf 0.1 (CNTs) 0.05 ribbons can be established in Fig. 4 a; only one unit cell is presented in every grain. Two possible interface models of magnified Sm(Co,Hf) 7 (CNTs) x boundary phase corresponding to interface shown in Fig. 4 a are presented in Fig. 4 b and c, where the z -axis of Sm(Co,Hf) 7 is parallel and perpendicular to the axial direction of the CNTs, respectively. Although the interface width and inner diameter of CNTs are both larger than the cell parameters of hte Sm(Co,Hf) 7 phase, it does not imply that the entire Sm(Co,Hf) 7 unit cell can enter into the interior of the CNTs. Therefore, the unit cell location and the number of Sm(Co,Hf) 7 units inside CNTs cannot be accurately determined. The model is merely intended to describe the possible structure of the grain boundary phase caused by the interaction among Sm–Co–Hf–CNTs. 3.3 Magnetic properties Fig. 5 shows the hysteresis loops of SmCo 6.9 Hf 0.1 (CNTs) 0.05 as-cast alloy and ribbons melt-spun at different speeds. The loops are all measured under the maximum field of 20 kOe. All ribbon samples were magnetized by a 50 kOe pulse magnetic field prior to the VSM measurement. Moreover, it is found that even measured under an applied field of 90 kOe, the magnetization of all samples is still unsaturated, so the maximum magnetization M s2T under 20 kOe is used to represent the saturation magnetization M s . As the quenching speed increases, the change in hysteresis loops in the second quadrant indicates in increase in coercivity H ci and remanence M r . Table 1 shows the magnetic properties, ribbon thickness and remanence ratio M r / M s2T . The remanence ratio and coercivity of as-cast bulk alloys are extremely low. However, the alloy displays relatively high magnetization M s2T . The low coercivity is due to the big grain size of as-cast alloy and the poor pinning effect of Hf(CNTs) on grain boundaries. M s2T is high due to Sm(Co,Hf) 7 main phase, while M r is low because the grains have no preferred orientations. As the quenching speed increases from 10 to 50 m s −1 , the ribbon thickness, coercivity, remanence and remanence ratio change from 80.56 μm, 2.564 kOe, 16.29 emu g −1 and 0.31 to 42.40 μm, 18.781 kOe, 66.79 emu g −1 and 0.87, respectively. If the quenching speed is higher than 30 m s −1 , the remanence ratio can exceed 0.5, implying that the exchange interaction among grains is enhanced and evident remanence enhancement is achieved. The ribbons melt-spun at 50 m s −1 display the best magnetic properties: H ci = 18.781 kOe, M s2T = 76.87 emu g −1 , M r = 66.79 emu g −1 and M r / M s2T = 0.87. The above analysis of the microstructure shows that on grain boundaries of the melt-spun ribbons, besides Sm and Co, there is a high content of Hf and CNTs. In addition, a quenching speed in excess of 40 m s −1 can result in a decrease in grain size and grain boundary width, as well as changes of grains from multidomain to single domain. Moreover, the C-rich Sm(Co,Hf) 7 (CNTs) x new phase can serve a similar role as the Sm(Co,Cu) 5 cell boundary phase in traditional Sm–Co–Cu–Fe–Zr sintered magnets and ultimately enhance the pinning effect. All the factors above can lead to a decrease or even disappearance of nucleation mechanism and an enhancement of the pinning mechanism during demagnetization. As a result, the coercivity increases. On the other hand, the Sm(Co,Hf) 7 (CNTs) x on grain boundaries is a magnetic phase, which does not dilute the magnetization of the main phase. At higher quenching speed, the ribbon thickness decreases, causing increasingly preferred cooling perpendicular to the ribbon surface. Meanwhile, the preferred cooling orientation of SmCo 7 is also its easy magnetization direction [13] . Therefore, the magnetization and remanence both increase, and remanence ratio also increases with quenching speed, implying an increase in orientation degree along the cooling direction of the ribbons. 4 Conclusions Melt-spun SmCo 6.9 Hf 0.1 (CNTs) 0.05 ribbons are prepared at speeds of 10–50 m s −1 , and the effects of quenching speed and CNTs on phase composition, microstructure and magnetic properties are studied. It can be concluded that SmCo 6.9 Hf 0.1 (CNTs) 0.05 as-cast alloys consist of Sm(Co,Hf) 7 as the main phase, a small amount of SmCo 5 and Hf(CNTs) phases. The ribbon powders melt-spun at speeds of 10–50 m s −1 consist of a single TbCu 7 -type structure. No amorphous phase is evident in the alloys. Hf(CNTs) phase of as-cast SmCo 6.9 Hf 0.1 (CNTs) 0.05 alloy are distributed on grain boundaries as discontinuous particles. The increase in quenching speed can cause a decrease in grain size and grain boundary thickness, as well as a more dispersed distribution of the grain boundary phase. The grains of the ribbons all have TbCu 7 structure, and C-rich Sm(Co,Hf) 7 (CNTs) x may be formed based on the CNT component. The increase in quenching speed can cause a decrease in the thickness of SmCo 6.9 Hf 0.1 (CNTs) 0.05 ribbons and an enhancement of coercivity, remanence and remanence ratio. If the quenching speed is higher than 30 m s −1 , the remanence ratio M r / M s2T can exceed 0.5. The ribbons melt-spun at 50 m s −1 display the best magnetic properties: H ci = 18.781 kOe, M s2T = 76.87 emu g −1 , M r = 66.79 emu g −1 and M r / M s2T = 0.87. Acknowledgments This work is supported by National Natural Science Foundation of Tianjin of China. The authors thank the Experimental Analysis Center of the School of Material Science and Engineering, Hebei University of Technology for characterization of the materials. References [1] R.T. Fingers C.S. Rubertus IEEE Trans Magn 36 2000 3373 [2] J.F. Liu Y. Zhang D. Dimitrov G.C. Hadjipanayis J Appl Phys 85 1999 2800 [3] Y.Q. Guo W. Li W.C. Feng J. Luo J.K. Liang Q.J. He Appl Phys Lett 86 2005 192513 [4] Y.Q. Guo W. Li J. Luo W.C. Feng J.K. Liang J Magn Magn Mater 303 2006 e367 [5] Y.Q. Guo W.C. Feng W. Li J. Luo J.K. Liang J Appl Phys 101 2007 023919 [6] J. Luo J.K. Liang Y.Q. Guo Q.L. Liu F.S. Liu Y. Zhang Intermetallics 13 2005 710 [7] T. Liu W. Li X.M. Li W.C. Feng Y.Q. Guo J Magn Magn Mater 310 2007 e632 [8] S. Aich J. Kostogorova J.E. Shield J Appl Phys 97 2005 10H108 [9] D.T. Zhang M. Yue J.X. Zhang L.J. Pan IEEE Trans Magn 43 2007 3494 [10] H.W. Chang S.T. Huang C.W. Chang C.H. Chiu W.C. Chang A.C. Sun J Appl Phys 101 2007 09K508 [11] http://www.billnt.com/chanpin.htm . [12] S. Reutzel J. Strohmenger T. Volkmann J. Gao D.M. Herlach Mater Sci Eng A 449–451 2007 709 [13] J.B. Sun Z.X. Zhang C.X. Cui W. Yang P. Guo D. Han J Alloys Compd 2008 10.1016/j.jallcom.2008.09.05",
        "keywords": [
            "Crystal structure",
            "Intermetallic compounds",
            "Magnetic properties",
            "Melt spinning",
            "Microstructure"
        ],
        "authors": [
            {
                "name": "Ji-Bing Sun",
                "org": ""
            },
            {
                "name": "Dan Han",
                "org": "School of Material Science and Engineering, Hebei University of Technology, Dingzigu Road, Hongqiao District, Tianjin 300130, China"
            },
            {
                "name": "Chun-Xiang Cui",
                "org": "School of Material Science and Engineering, Hebei University of Technology, Dingzigu Road, Hongqiao District, Tianjin 300130, China"
            },
            {
                "name": "Wei Yang",
                "org": "School of Material Science and Engineering, Hebei University of Technology, Dingzigu Road, Hongqiao District, Tianjin 300130, China"
            },
            {
                "name": "Liang Li",
                "org": "School of Material Science and Engineering, Hebei University of Technology, Dingzigu Road, Hongqiao District, Tianjin 300130, China"
            },
            {
                "name": "Fan Yang",
                "org": "School of Material Science and Engineering, Hebei University of Technology, Dingzigu Road, Hongqiao District, Tianjin 300130, China"
            }
        ],
        "venue": "Acta Materialia",
        "year": 2009
    },
    "n1qDdUPu": {
        "id": "n1qDdUPu",
        "title": "Effects of Hf and CNTs on magnetic transformation and thermal stabilities of TbCu7-type Sm–Co matrix ribbon magnets",
        "abstract": "SmCo 7 , SmCo 6.9 Hf 0.1 , SmCo 6.9 Hf 0.1 (CNTs) 0.05 and SmCo 6.9 Hf 0.1 (CNTs) 0.1 melt-spun ribbons are prepared at a speed of 40 m/s. The phase structure, magnetic transformation and thermal stability of the ribbons are studied using thermal analysis, high temperature in-situ XRD and thermomagnetic analysis. The results show the Hf and CNTs (carbon nanotubes) additions have no influence on the formation of TbCu 7 -type structure. Nevertheless, Hf addition may cause large heat storage; CNTs addition can lead to crystal-boundary blocking effect. The M – T curves of SmCo 7 matrix ribbons can all be divided into seven stages. The 1:7H decomposition, CoC x precipitation and 1:5 phase decrease successively emerge when the temperature increases from room temperature to 1100 °C. Keywords Rare earth alloys and compounds Rapid-solidification Phase transitions Thermal analysis X-ray diffraction",
        "keywords": [
            "Phase transitions",
            "Rapid-solidification",
            "Rare earth alloys and compounds",
            "Thermal analysis",
            "X-ray diffraction"
        ],
        "authors": [
            {
                "name": "Ji-Bing Sun",
                "org": ""
            },
            {
                "name": "Dan Han",
                "org": "School of Material Science and Engineering, Hebei University of Technology, Tianjin 300130, China"
            },
            {
                "name": "Chun-Xiang Cui",
                "org": "School of Material Science and Engineering, Hebei University of Technology, Tianjin 300130, China"
            },
            {
                "name": "Wei Yang",
                "org": "School of Material Science and Engineering, Hebei University of Technology, Tianjin 300130, China"
            },
            {
                "name": "Hao Zhou",
                "org": "School of Material Science and Engineering, Hebei University of Technology, Tianjin 300130, China"
            },
            {
                "name": "Rui-Ting Tian",
                "org": "School of Material Science and Engineering, Hebei University of Technology, Tianjin 300130, China"
            },
            {
                "name": "Li-Guo Yang",
                "org": "School of Material Science and Engineering, Hebei University of Technology, Tianjin 300130, China"
            }
        ],
        "venue": "Journal of Alloys and Compounds",
        "year": 2009
    },
    "8ULcGXpE": {
        "id": "8ULcGXpE",
        "title": "Crack growth versus blunting in nanocrystalline metals with extremely small grain size",
        "abstract": "Fracture of nanocrystalline metals with extremely small grain size is simulated in this paper by structural evolution. Two-dimensional scheme is formulated to study the competition between crack growth and blunting in nanocrystalline samples with edge cracks. The scheme couples the creep deformation induced by grain boundary (GB) mechanisms and the intergranular crack growth. The effects of material properties, initial configurations and applied loads are explored. Either the enhancement in diffusion mobility, or the deterrence in the grain boundary damage, would blunt the crack and decelerate its growth, and vice versa. The simulations agree with the analytical predictions as modified from that of Yang and Yang [2008. Brittle versus ductile transition of nanocrystalline metal. Int. J. Solids Struct. 45, 3897–3907]. Upon the suppression of dislocation activities, it is validated that the brittle versus ductile transition of nanocrystals is controlled by the development of grain boundary-dominated creep versus grain boundary decohesion. Further simulations found that either decreasing the grain sizes or increasing the dispersion of grain sizes would blunt the growing cracks.",
        "keywords": [
            "grain boundaries",
            "polycrystalline material",
            "energy methods",
            "fracture",
            "diffusion",
            "material properties",
            "dislocations",
            "grain size",
            "grain boundary"
        ],
        "authors": [
            {
                "name": "Fan Yang",
                "org": "Department of Engineering Mechanics, Tsinghua University, Beijing 100084, China"
            },
            {
                "name": "Wei Yang",
                "org": ""
            }
        ],
        "venue": "Journal of the Mechanics and Physics of Solids",
        "year": 2009
    },
    "1a3AxJK7": {
        "id": "1a3AxJK7",
        "title": "Sm 12 Co 59 Cu 6 Fe 20 Zr 3 sintered magnets made from as-cast alloy and melt-spun ribbons",
        "abstract": "",
        "keywords": [
            "comparative study",
            "microstructures",
            "permanent magnet",
            "solid solution",
            "phase transitions",
            "x ray diffractometer",
            "permanent magnets",
            "magnetic properties",
            "microstructure",
            "phase transition",
            "electron microscope",
            "cell wall"
        ],
        "authors": [
            {
                "name": "jibing sun",
                "org": ""
            },
            {
                "name": "zhexu zhang",
                "org": ""
            },
            {
                "name": "chunxiang cui",
                "org": ""
            },
            {
                "name": "wei yang",
                "org": ""
            },
            {
                "name": "liang li",
                "org": ""
            },
            {
                "name": "dan han",
                "org": ""
            },
            {
                "name": "liguo yang",
                "org": ""
            }
        ],
        "venue": "Journal of Alloys and Compounds",
        "year": 2009
    },
    "aXmuqmDt": {
        "id": "aXmuqmDt",
        "title": "Sm12Co59Cu6Fe20Zr3 sintered magnets made from as-cast alloy and melt-spun ribbons",
        "abstract": "A comparative study between Sm 12 Co 59 Cu 6 Fe 20 Zr 3 master alloy magnet and melt-spun ribbon magnet is made by applying the same traditional sintering-solid solution-aging-slow cooling method. The X-ray diffractometer, electron microscope and magnetometer are employed to investigate the structure and magnetic properties of the magnets. It is found that two types of sintered magnets are formed both of which have Th 2 Zn 17 -type main phase. Master alloy sintered magnet has a typical cellular structure, with average cell size of 88.3 nm and cell wall width less than 20 nm, and the comprehensive magnetic properties are: H ci = 21.1 kOe, M r = 75.9 emu/g and M s9T = 107.8 emu/g. The coercivity of the ribbons melt-spun at a speed of 20 m/s is merely 2.1 kOe, while in ribbon sintered magnet, this value can approach as high as 27.4 kOe, together with remanence 61.8 emu/g and maximum magnetization M s9T = 103.6 emu/g. A typical cellular–lamellar microstructure is obtained in ribbon sintered magnet, with average cell size of 102.3 nm, cell wall width less than 10 nm and lamellar size of 1–3 nm. The high-coercivity of ribbon sintered magnet can be attributed to the following factors: the existence of lamellar phases, larger cell size, thinner cell walls, more cell boundary phases and desirable composition distribution. Keywords Permanent magnets Rapid-solidification Microstructure Phase transitions Magnetic measurements 1 Introduction Permanent magnets for high-temperature applications are a research area of great scientific and industrial interest. Sm–Co-type magnets have retained their dominance at elevated temperatures due to their high magnetocrystalline anisotropy and high Curie temperature [1] . Up till now, powder metallurgy is the most commonly used process to produce Sm 2 Co 17 -type permanent magnets because of its high technical maturity. Currently, there are mainly two methods to improve the operating temperature of this type of Sm–Co magnets [2,3] : the first is to increase the intrinsic coercivity H ci at room temperature while keeping intrinsic coercivity temperature coefficient unchanged; the second is to minimize the absolute value of intrinsic coercivity temperature coefficient on the premise of retaining appropriate H ci value. Nevertheless, the magnetic properties of low-temperature-coefficient permanent magnets may be deteriorated due to the addition of some heavy rare earth elements. Therefore, in the studies of Sm–Co magnets, to improve the coercivity at room temperature still deserves much attention. The coercivity of Sm 2 Co 17 (for short 2:17) based magnets is attributed to the pinning of domain walls at the cell walls of the SmCo 5 -type (for short 1:5H) structure between the pyramidal cells of the 2:17 structure. In terms of micromagnetism, Kronmüller and co-workers [5,8] and Kronmüller and Goll [4,6,7] made a thorough study on coercivity mechanism of Sm(Co, Cu, Fe, Zr) z both in experiment and theory. They have reported that with the increase in temperature, coercivity is dominated by repulsive pinning, attractive pinning and nucleation mechanism, successively. The coercivity of Sm(Co bal Fe 0.1 Cu 0.088 Zr 0.02 ) 7.5 magnets changes slightly as the temperature increases, and can approach 10 kOe at 500 °C. While the Sm(Co bal Fe 0.1 Cu 0.088 Zr 0.04 ) 8.5 magnet prepared by Hadjipanayis et al. [9] displayed the maximum coercivity of 42.2 kOe at room temperature, and could retain a coercivity of 8.2 kOe at 500 °C. Recently, another path to obtain high-coercivity magnets is to prepare melt-spun ribbons. But the coercivity of melt-spun Sm–Co alloy is lower than that of traditional sintered magnets [10] . It has been reported that Sm(Co, Fe, Cu, Zr) z ( z = 7.4–8.0) ribbons melt-spun at speeds of 5–53 m/s all consist of a TbCu 7 -type structure, whereas a cellular microstructure similar to that of traditional sintered magnets is obtained after annealing. The coercivity of 4.74–28.1 kOe at room temperature and 0.53 T at 500 °C of such ribbons was obtained [11–18] . Goll et al. [19] reported that by applying to ribbons an annealing procedure similar to that of sintered magnets, an analogous cellular microstructure can be obtained, which also leads to an abnormal temperature dependence of coercivity. Makridis et al. [20] prepared Sm(Co 0.74 Fe 0.1 Cu 0.12 Zr 0.04 B x ) 7.5 melt-spun ribbons at speeds of 10–70 m/s, and discovered that all of the ribbons consist of TbCu 7 -type and fcc Co phases, with a remanence ratio higher than 0.8 and a maximum coercivity of 38.5 kOe for x = 0.04. However, at present there is no effective way to prepare sintered magnets using ribbon powders, and it still remains to be solved that whether the properties of this kind of magnets are superior to those of traditional sintered magnets. In this paper, by adopting the same sintering process, two groups of Sm(Co bal Cu 0.067 Fe 0.222 Zr 0.033 ) 7.5 magnets with typical components, namely Sm 12 Co 59 Cu 6 Fe 20 Zr 3 samples were treated by traditional powder metallurgy method and melt-spun method, respectively. A comparative study between these two types of samples was carried out and the structure and magnetic properties of the magnets were studied. 2 Experimental Sm 12 Co 59 Cu 6 Fe 20 Zr 3 alloy was prepared by medium frequency induction furnace using high purity metals in argon atmosphere. Extra 3% Sm was added to the samples to compensate for the weight loss during melting. Parts of ingots were then melt-spun at 20 m/s by LZ-12A overflow-type vacuum quenching furnace under purified argon with a pressure of 0.6 × 10 5 Pa. The thickness of the ribbons was 60–100 μm. The ribbons were air-cooled after vacuum annealed at 700 °C for 20 min. Then the annealed ribbons and primarily crushed master alloy were milled using a QQM ball mill at a speed of 90 rpm for 5 and 12 h, respectively, and a powder particle size of 2–8 μm was obtained by this process. These two types of powders were then oriented and compression moulded by a nonmagnetic steel mould at a magnetic field of 20 kOe. All cylinder blanks were compacted through cold isostatic pressing under 300 MPa. Then all compacts were sintered first at 1190 °C for 0.5 h, then at 1210 °C for 0.5 h, followed by a solution treatment at 1190 °C for 1 h, and then air cooling. After that, an isothermal aging process was applied at 850 °C for 10 h. Then the compacts were cooled at a constant speed of 0.5 °C/min to 400 °C and kept at 400 °C for 10 h. Finally, after air-cooled to room temperature, “ribbon sintered magnet” and “master alloy sintered magnet” can be obtained. These two kinds of sintered magnets were cut into thin slices in the size of 3 mm × 3 mm × 0.5 mm by wire cutting perpendicular to their magnetic alignment directions. The demagnetization curves of the slices were then measured by physical property measurement system (PPMS) under a magnetic field of 90 kOe. The magnetic properties of the ribbons were directly measured by Lakeshore 7407 vibrating sample magnetometer (VSM). The phase analysis was made with a Rigaku Dmax 2500 Pc X-ray diffractometer (XRD) with Cu Kα radiation. The microstructure and composition were observed by Philips Tecnai F20 transmission electron microscopy (TEM) and Philips XL30 scanning electron microscopy (SEM). 3 Results and discussion 3.1 Phase analysis Sm 12 Co 59 Cu 6 Fe 20 Zr 3 as-cast master alloy mainly consists of Th 2 Zn 17 -type Sm 2 (Co, M) 17 (M = Fe, Cu, Zr) phase (for short 2:17R) (see Fig. 1 a ). Compared with 2 2 0 diffraction peak, which is the strongest one of the 2:17R phase, the 0 0 6 diffraction peak along the easy magnetization direction of the 2:17R is relatively low, which indicates there is no evident [21] preferred orientation growth in the as-cast master alloy during cooling. The ribbons prepared by as-cast master alloy, which are melt-spun at 20 m/s, mainly consist of TbCu 7 -type Sm(Co, M) 7 (M = Fe, Cu, Zr) phase (for short 1:7H) (see Fig. 1 b), and the grain size is approximately 50 nm, which was determined with Scherer formula according to the full width at half maximum (FWHM) of 1 0 1, 1 1 0, 2 0 0, 1 1 1, 0 0 2 and 2 0 1 diffraction peaks. Fig. 2 shows the XRD patterns of the Sm 12 Co 59 Cu 6 Fe 20 Zr 3 master alloy sintered magnet and ribbon sintered magnet obtained by the same sintering process. The two samples both consist of 2:17R phase, which implies that the phase transition, SmCo 1:7H → SmCo 2:17R+SmCo 1:5, takes place in the ribbon sample. The 0 0 6 diffraction peaks of both samples become very strong because of oriented pressing prior to sintering. Particularly, in Fig. 2 a which shows the XRD pattern of master alloy sintered magnet, some other main diffraction peaks of 2:17R phase (e.g. (2 2 0), (3 0 0) and (1 1 3)) have almost vanished, and the peaks of 1:5 phase cannot be found while they are supposed to exist. While those diffraction peaks of 2:17R phase in ribbon sintered magnet (shown in Fig. 2 b) are more obvious, which indicates that its orientation degree is considerably inferior to that of master alloy sintered magnet. Three reasons may account for that phenomenon: firstly, the grain size of the ribbons is several tens of nanometer, while the ribbon powders with particle size of several micrometer obtained by ball milling are polycrystalline, which may not be able to make all small grains in the same powder to ensure a consistent orientation; secondly, though not obvious, a small amount of amorphous phase is supposed to exist in the ribbons, and such phase is hard to magnetize to [0 0 1] alignment direction; thirdly, evident 1:7H phase decomposition occurs in the ribbons during sintering. Though 1:7H, 2:17R, 1:5H and even 2:17H phases have the same easy magnetization direction of [0 0 1], the decomposition of the 1:7H phase is a process characterized by structural remodeling and atomic diffusion of all phases, which may destroy the original orientation degree, and only parts of [0 0 6] orientations are maintained. Compared to as-cast master alloys, melt-spun ribbons deserve less milling time to be crushed during preparation process, and nano-crystalline powders are obtained simultaneously. 3.2 Analysis of magnetic properties Fig. 3 shows the demagnetization curves of two kinds of sintered magnets and melt-spun ribbons. The Sm 12 Co 59 Cu 6 Fe 20 Zr 3 ribbons melt-spun at 20 m/s display the worst magnetic properties: intrinsic coercivity H ci = 2.1 kOe, remanence M r = 30.1 emu/g, magnetization at 20 kOe M s2T = 107.8 emu/g. The ribbon sintered magnet displays an extremely high H ci of 27.4 kOe, and other properties are listed as follows: M r = 61.8 emu/g, maximum magnetic energy product (BH) max = 12.86 MGOe and magnetization at 90 kOe M s9T = 103.6 emu/g. While the properties of master alloy sintered magnet are: H ci = 21.1 kOe, M r = 75.9 emu/g and M s9T = 107.8 emu/g. The remanence of master alloy sintered magnet is higher than that of its ribbon sintered counterpart, while its coercivity is relatively low. This is because the remanence of sintered magnets is mainly proportional to the orientation degree, and according to Fig. 2 , master alloy sintered magnet displays a better orientation degree than ribbon sintered magnet. There are still two evident deficiencies of the magnetic properties, which are relatively low remanence and poor square degree of the demagnetization curves. 3.3 Analysis of microstructure Fig. 4 shows the TEM image of the Sm 12 Co 59 Cu 6 Fe 20 Zr 3 ribbons melt-spun at 20 m/s. All grains show regular morphology, and no evident amorphous regions are found. Thus, the content of amorphous phases should be very low, which is consistent with the XRD result in Fig. 1 b. The results of selected area electron diffraction (SAED) reveal that the grains mainly consist of Sm(Co, M) 7 phase. The average grain size is 47 nm, while the size of grains is non-uniform. For instance, the grains in area A and area B are different. In addition, it can be seen that the grains of the ribbons are directly contacted and there is no evidence of grain boundary phase, which results in the predominant control of nucleation field on coercivity, and the effect of pinning field is negligible, so the coercivity of the ribbons is only 2.1 kOe. The backscattered electron images (BSE) of master alloy sintered magnet and ribbon sintered magnet are also observed in Fig. 5 . These two kinds of magnets are both compact, with no obvious cavities being found. Furthermore, there are three kinds of contrast areas in the magnets, and they are the gray matrix phase, white granular phase which is mainly distributed along the grain boundaries and the black dots caused by the slight collapse of the sample. We have learned from Fig. 2 that the matrix phases of the two sintered magnets are both 2:17R. The results of energy-dispersive spectroscopy (EDS) also reveal that the average compositions of master alloy sintered magnet and ribbon sintered magnet are Sm 11.26 Co 59.30 Cu 6.02 Fe 21.64 Zr 1.78 and Sm 11.24 Co 59.33 Cu 6.02 Fe 21.27 Zr 2.15 , respectively, and the latter has a relatively high Zr content. The grain size of the gray area of master alloy sintered magnet ranges from several micrometers to about 30 μm, which is smaller than its ribbon sintered counterpart. The white phase is the oxide of the Sm–Co–Cu–Fe–Zr phase, with the O concentration of 10.35–30.32 at% and Sm concentration of 14.38–35.31 at%. It seems that the oxides in master alloys are more dispersed and much higher in content. At 25 kV the excited volume of backscattered electrons must be fairly large, so most of the signal probably came from the matrix. The much larger amount of the oxide phase in the master alloy magnet could be a result of the longer milling, and this excessive oxidation may explain both the smaller average grain size (the oxide inclusions have inhibited the grain growth during sintering) and poor resulting magnetic properties. Fig. 6 is the cellular microstructure TEM images of the master alloy sintered magnet. A fine cellular microstructure is obtained by sintering process. The average cell size is 88.3 nm, and the cell wall has the maximum width of 20 nm ( Fig. 6 c), with a similar morphology to that described in references [7,22] . Fig. 7 shows the typical cellular and lamellar structure of the ribbon sintered magnet. The average cell size is 102.3 nm, and the cell wall has the maximum width of 10 nm, with a similar morphology to that described in reference [23] . The 2:17R phase is the majority phase of the material. The 1:5 cell boundary phase is coherent (or at least semi-coherent) with the cell interior. A so-called lamellar phase (also referred to as platelet or Z-phase) rich in Zr is observed in Fig. 7 b, this Z-phase manifests itself as thin lines extending over many 2:17R cells. The thickness of the lamellae is very small ranging from 1 to 3 nm ( Fig. 7 c). Most people [4,6,24] agree that Z-phase behaves a 2:17H-type structure and additionally parallel to the 2:17R basal plane. Sm 2 (Co, Fe) 17 main phase is the major source of the high saturation magnetization, and the Sm(Co, Cu) 5 cell boundary phase can enhance the coercivity by pinning domain walls. The Z-phase is considered to stabilize the cellular microstructure and, more importantly, to provide diffusion paths for Cu, Fe and Co, thereby modifying phase-ordering kinetics, and promoting formation of uniform Sm(Co, Cu) 5 phase in cell boundaries. Furthermore, it is reported that the 2:17R main phase is rich in Co and Fe while the cell boundary phase is rich in Cu and Sm. During slow cooling to 400 °C, the Cu is not uniformly distributed in the cell boundaries, but rather distributes in a large gradient and thus increases the coercivity [23,25] . However, what is different from reference [23] is that in their work, the lamellar structure and cell structure were observed from parallel or perpendicular to the imaging plane, while we observe them only at different positions of the same sample plane. Moreover, in reference [23] the coercivity at room temperature of the Sm(Co 0.784 Fe 0.100 Cu 0.088 Zr 0.028 ) 7.19 sample is less than 25 kOe. No lamellar Z-phase is discovered on the master alloy sintered magnet surface shown in Fig. 6 , which may mean that master alloy sintered magnet has less lamellar phase than ribbon sintered magnet does. Generally, Zr is found to be enriched in lamellar phases. As mentioned above, lamellar phases can provide diffusion paths for Cu, Fe and Co. If the content of lamellar phases is at a low level, then Cu, Fe, Co and other atoms may enter into cell boundaries at a much lower speed in the same treatment period, therefore the content of cell boundary phase may decrease and Zr may be enriched in other phases. In addition, the average cell size of ribbon sintered magnet is larger than that of master alloy sintered magnet, which is consistent with results reported in reference [3] , that the low H ci magnets generally exhibit smaller cell structure (50 nm) and the high H ci magnets exhibit larger cell structure (100 nm). Through all cells marked by numbers, particularly the regions highlighted by white cycles in Figs. 6b and 7a , it can be found that the content of cell boundary phases in master alloy sintered magnet is indeed less than that in ribbon sintered magnet, moreover, its cell boundary is wider, with different morphology compared to ribbon sintered magnet, which may be related to the contents of different elements in cell boundary phases. The coercivity of Sm–Co–Cu–Fe–Zr magnets is closely related to the compositions and structures of cell boundary phases [7] . Golla et al. [5] and Goll and co-workers [6] reported that the increase in the coercivity during the slow cooling process was due to the formation of the ordered 1:5 phase, which did not exist after the high-temperature annealing treatments. After these treatments only the 1:5 composition existed. The transition to the ordered 1:5 phase was enhanced by the diffusion of Cu into the cell wall via the Zr-rich Z-phase. Recently, Gopalan et al. [25] confirmed Cu was enriched at the cell boundary 1:5 phase and the concentration profile of the elements in the 1:5 phase in the low-coercivity sample appeared broader than that in high-coercivity sample, which is absolutely consistent with our cell wall width data. Thus, though cellular structure is also obtained in master alloy sintered magnet, its composition distribution is not as desirable as ribbons sintered magnet because of relatively low content of cell walls and lamellar phases. The lower coercivity of the master alloy sintered magnets may be also due to the reduced diffusion of Cu into the cell wall. In conclusion, five factors may lead to a higher coercivity of ribbon sintered magnet: the existence of lamellar phases, larger cell size, thinner cell walls, more cell boundary phases and desirable composition distribution, particularly Cu gradient distribution in cell walls. Before the sintering process, the grain size of the ribbons is only about 50 nm, which is far less than micron order of magnitude of master alloys. During sintering, when the ribbons are heated to 1210 °C, the structural phase transformation of 1:7H→2:17 + 1:5H would occur first [26] , that is, 2:17 and 1:5H would precipitate from the same parent phase, which is a process of structural remodeling and could accelerate the formation of cellular microstructure. When continued to be heated, the grains begin to grow, while over-growth will not happen due to the obstruction of cell boundary phase. But for master alloy sintered magnet, tinny and randomly distributed Cu-rich 1:5H phase will first precipitate from 2:17 matrix when the samples are heated to 1190 °C and solid solution treated (homogenized), and cellular structure will be formed during aging at 850 °C [8] . The maximum coercivity and effective magnetocrystalline anisotropy cannot be formed until a two-step process after aging is carried out, which is firstly cooling from 850 to 400 °C at a speed of 0.5–1.0 °C/min and then quenching to room temperature [7] . Therefore, it is apparent that the formation of cellular 2:17 and 1:5 structures in ribbon sintered magnet is a process characterized by phase transformation and diffusional precipitation, while in master alloy sintered magnet, only diffusional precipitation accounts for the formation. Thereby, lamellar phases and a reasonable composition distribution seem to be easier to obtain in ribbon magnet. 4 Conclusions In this paper, a comparative study between Sm 12 Co 59 Cu 6 Fe 20 Zr 3 master alloy magnet and melt-spun ribbon magnet is made by traditional sintering-solid solution-aging-slow cooling method. It can be concluded as follows: (1) As-cast Sm 12 Co 59 Cu 6 Fe 20 Zr 3 master alloy mainly consists of Th 2 Zn 17 -type phase. While the ribbons melt-spun at 20 m/s mainly consist of TbCu 7 -type phase, with a grain size of approximately 47 nm. The orientation degree of powders crushed from master alloy under same magnetic field is higher than that of ribbon powders. (2) The main phases of master alloy sintered magnet and ribbon sintered magnet are both Th 2 Zn 17 -type structure, and the decomposition of SmCo 1:7H happens in the ribbon samples during sintering process. (3) Typical cellular structure is obtained in master alloy sintered magnet. The average cell size is 88.3 nm and cell wall width is less than 20 nm. Its magnetic properties are: H ci = 21.1 kOe, M r = 75.9 emu/g, M s9T = 107.8 emu/g. The coercivity of the ribbons melt-spun at 20 m/s is only 2.1 kOe, while in ribbon sintered magnet, this value can approach as high as 27.4 kOe, together with remanence 61.8 emu/g, maximum energy product (BH) max = 12.86 MGOe and maximum magnetization M s9T = 103.6 emu/g, but the square degree of its demagnetization curve is relatively inferior. Typical cellular and lamellar microstructure is obtained in ribbon sintered magnet. Its average cell size is 102.3 nm, together with cell wall width below 10 nm and lamellar size of 1–3 nm. (4) It is assumed that five factors may lead to the high-coercivity of ribbon sintered magnet: the existence of lamellar phases, larger cell size, thinner cell walls, more cell boundary phases and desirable composition distribution. Acknowledgements This work is supported by Tianjin Natural Science Foundation of China with No. 09JCZDJC22800. And this work is partly supported by Doctoral Fund of Ministry of Education of China (No. 20060080005). The authors thank the Experimental Analysis Center of School of Material Science and Engineering, Hebei University of Technology for the Materials Characterization. References [1] M.S. Walmer C.H. Chen M.H. Walmer IEEE Trans. Magn. 36 2000 3376 3381 [2] A.S. Kim J. Appl. Phys. 83 1998 6715 6717 [3] A.S. Kim J. Appl. Phys. 81 1997 5609 5611 [4] H. Kronmüller D. Goll J. Magn. Magn. Mater. 272–276 2004 e319 e320 [5] D. Goll H. Kronmüller H.H. Stadelmaier J. Appl. Phys. 96 2004 6534 6545 [6] H. Kronmüller D. Goll Scripta Mater. 48 2003 833 838 [7] H. Kronmüller D. Goll Scripta Mater. 47 2002 545 550 [8] W. Tang Y. Zhang D. Goll G.C. Hadjipanayis H. Kronmüller J. Magn. Magn. Mater. 226 2001 1365 1366 [9] G.C. Hadjipanayis W. Tang Y. Zhang S.T. Chui J.F. Liu C. Chen H. Kronmüller IEEE Trans. Magn. 36 2000 3382 3387 [10] M.W. Crabbe H.A. Davies R.A. Buckley IEEE Trans. Magn. 30 1994 696 698 [11] R. Gopalan D.H. Ping K. Hono M.Q. Huang B.R. Smith Z. Chen B.M. Ma J. Appl. 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Gopalan V. Chandrasekaran S. Ram J. Alloys Compd. 432 2007 23 29 [22] Y. Zhang Q. Zeng G.C. Hadjipanayis J. Appl. Phys. 97 2005 10H107 [23] O. Gutfleisch K.H. Müller K. Khlopkov M. Wolf A. Yan R. Schafer T. Gemming L. Schultz Acta Mater. 54 2006 997 1008 [24] W. Tang Y. Zhang G.C. Hadjipanayis J. Magn. Magn. Mater. 221 2000 268 272 [25] R. Gopalan K. Hono A. Yan O. Gutfleisch Scripta Mater. 60 2009 764 767 [26] S.S. Makridis I. Panagiotopoulos I. Tsiaoussis N. Frangis E. Pavlidou K. Chrisafis G.F. Papathanasiou K. Efthimiadis G.C. Hadjipanayis D. Niarchos J. Magn. Magn. Mater. 320 2008 2322 2329",
        "keywords": [
            "Magnetic measurements",
            "Microstructure",
            "Permanent magnets",
            "Phase transitions",
            "Rapid-solidification"
        ],
        "authors": [
            {
                "name": "Ji-bing Sun",
                "org": ""
            },
            {
                "name": "Zhe-xu Zhang",
                "org": "School of Material Science and Engineering, Hebei University of Technology, Tianjin 300130, PR China"
            },
            {
                "name": "Chun-xiang Cui",
                "org": "School of Material Science and Engineering, Hebei University of Technology, Tianjin 300130, PR China"
            },
            {
                "name": "Wei Yang",
                "org": "School of Material Science and Engineering, Hebei University of Technology, Tianjin 300130, PR China"
            },
            {
                "name": "Liang Li",
                "org": "School of Material Science and Engineering, Hebei University of Technology, Tianjin 300130, PR China"
            },
            {
                "name": "Dan Han",
                "org": "School of Material Science and Engineering, Hebei University of Technology, Tianjin 300130, PR China"
            },
            {
                "name": "Li-guo Yang",
                "org": "School of Material Science and Engineering, Hebei University of Technology, Tianjin 300130, PR China"
            },
            {
                "name": "Li-jie Li",
                "org": "School of Material Science and Engineering, Hebei University of Technology, Tianjin 300130, PR China"
            }
        ],
        "venue": "Journal of Alloys and Compounds",
        "year": 2009
    },
    "ysKpU5PR": {
        "id": "ysKpU5PR",
        "title": "Kinetics and size effect of grain rotations in nanocrystals with rounded triple junctions",
        "abstract": "A kinetic model is developed to quantify the rate of grain rotations driven by either grain boundary energy or stress. The critical roles of triple junctions and grain shape are emphasized. The size effects for the rotation rate are analyzed. As the grain size decreases, the model predicts shifts in the dominating driving forces and dissipation mechanisms.",
        "keywords": [
            "grain boundary sliding",
            "grain boundary diffusion",
            "kinetics",
            "nanocrystals",
            "grain rotation",
            "grain boundary"
        ],
        "authors": [
            {
                "name": "Fan Yang",
                "org": "AML, Department of Engineering Mechanics, Tsinghua University, Beijing 100084, China"
            },
            {
                "name": "Wei Yang",
                "org": ""
            }
        ],
        "venue": "Scripta Materialia",
        "year": 2009
    },
    "phWfiPLY": {
        "id": "phWfiPLY",
        "title": "Effects of Hf and CNTs on structure and magnetic properties of TbCu 7 -type Sm–Co magnets",
        "abstract": "",
        "keywords": [
            "x ray diffractometer",
            "electron microscope",
            "microstructures",
            "grain boundary",
            "magnetic properties"
        ],
        "authors": [
            {
                "name": "jibing sun",
                "org": ""
            },
            {
                "name": "dan han",
                "org": ""
            },
            {
                "name": "chunxiang cui",
                "org": ""
            },
            {
                "name": "wei yang",
                "org": ""
            },
            {
                "name": "liang li",
                "org": ""
            },
            {
                "name": "fan yang",
                "org": ""
            },
            {
                "name": "liguo yang",
                "org": ""
            }
        ],
        "venue": "Intermetallics",
        "year": 2010
    },
    "5JJEGGzy": {
        "id": "5JJEGGzy",
        "title": "Effects of Hf and CNTs on structure and magnetic properties of TbCu7-type Sm–Co magnets",
        "abstract": "SmCo 7 , SmCo 6.9 Hf 0.1 , SmCo 6.9 Hf 0.1 (CNTs) 0.05 and SmCo 6.9 Hf 0.1 (CNTs) 0.1 as-cast alloys and ribbons melt-spun at the speed of 40 m/s are prepared. The X-ray diffractometer, electron microscope and magnetometer are employed to investigate the effects of Hf and CNTs on structure and magnetic properties of the as-cast alloys and ribbons. The results show that Hf and CNTs additions in SmCo 7 alloys can stabilize TbCu 7 structure. Hf addition can form HfCo 2 grain boundary phase. Fine dispersed Hf(CNTs) grain boundary phase can be derived from simultaneous addition of Hf and CNTs. The four types of ribbons all consist of TbCu 7 -type Sm(Co,Hf) 7 main phase. Cooling rate is the key factor of forming TbCu 7 -type phase. It is attempted that the grain boundaries with CNTs addition mainly consist of Sm(Co,Hf) 7 (CNTs) x . The coercivity, remanence and remanence ratio of the ribbons all increase with Hf and CNTs additions. The comprehensive magnetic properties of SmCo 6.9 Hf 0.1 (CNTs) 0.05 ribbons are H ci = 13.95 kOe, M r = 48.85 emu/g, M 2T = 61.09 emu/g and M r /M 2T = 0.80. Excessive CNT addition may worsen the magnetic properties. Keywords A. Rare-earth intermetallics B. Magnetic properties C. Rapid solidification processing D. Microstructure 1 Introduction The trend in both military and commercial markets for greater affordability has prompted the electromechanical designer toward higher speed and higher operating temperature devices. New magnetic materials are essential for the success of many of these power generation, distribution, and utilization systems [1] . Among all the existing high performance rare-earth permanent magnets, only Sm–Co matrix magnets can work at over 400 °C. Most high-temperature permanent magnets are Sm 2 Co 17 –SmCo 5 two-phase magnets characterized by a cellular microstructure and pinning-controlled coercivity, and at 500 °C coercivity of up to 10 kOe have been obtained in optimized magnets [2] . Recently interest has been focused on Sm(Co,M) 7 (M = stabilizing element) compounds with TbCu 7 -type structure (space group P6/mmm) due to their potential applications as novel high temperature rare earth permanent magnets. The composition of SmCo 7 lies between that of SmCo 5 and Sm 2 Co 17 . However, pure SmCo 7 phase can not steadily exist, so a third element such as Si, Cu, Ga, Nb or Hf, is necessary to stabilize the TbCu 7 -type Sm–Co 1:7 phase and to improve its magnetic properties. Guo and his coworkers [3–7] directly prepared some Sm–Co 1:7 intermetallic compounds by arc melting. Among those third elements M, Hf has been reported the most powerful both in stabilizing the TbCu 7 -type structure and in enhancing its magnetocrystalline anisotropy field, meanwhile, it possesses high magnetization. Aich et al. [8,9] have reported that the structure of SmCo 7 can be changed by adding Nb or C. They concluded that Nb could stabilize TbCu 7 -type structure and tended to reduce the amount of long-range order Sm 2 Co 17 , while C could reduce the scale of the microstructure and form an intergranular phase that effectively isolated the hard magnetic SmCo 7 grains from each other. The alloy ribbons melt-spun at 40 m/s had a maximum coercivity of 9 kOe when annealed at 800 °C, but heat treatment led to the precipitation of NbC. Zhang et al. [10] prepared bulk nanocrystalline SmCo 6.6 Nb 0.4 sintered magnet with TbCu 7 -type structure by spark plasma sintering (SPS) technique, the magnet exhibited good thermal stability with a coercivity of 0.48 T at 500 °C and coercivity temperature coefficient β of -0.169 %/K. Chang et al. [11] prepared SmCo 7− x Hf x C y ribbons with TbCu 7 -type structure from the ingots under a wheel speed of 40 m/s. They found a slight C addition was helpful in refining the grain size of the ribbons, and the maximum coercivity of 11.8 kOe was obtained. Small amount of face-centered cubic Co phase and Sm 2 Co 17 phase existed in C-containing ribbons, and a slight nonmagnetic Sm 2 C 3 phase for higher C addition of y = 0.14 was present. Therefore, it is obvious that C addition in Sm(Co,M) 7 alloys is effective in refining the grain size and pinning the domain walls. On the other hand, the formation of nonmagnetic adnascent phase is inevitable. Carbon Nanotube (CNTs) are one dimensional nano-material with hexcirclic structure. They are characterized by good thermal conductivity (∼6000 W m −1 K −1 ), vacuum stability (2800 °C), good adsorbability and inertness, which make CNTs potentially a component of ideal pinning phase. Therefore, CNTs are added into Sm(Co,Hf) 7 alloys, and the effects of CNTs and Hf on phase structure and magnetic properties of SmCo 7 -type alloys are studied in this paper. 2 Experimental The multiwall CNTs (MWCNTs) used in this study, which were prepared by chemical vapor deposition (CVD), were purchased from a commercial supplier. Their characteristics are listed as follows: inner diameter 5–10 nm, external diameter 25–70 nm, and length of several micrometers to tens of micrometers, as shown in Fig. 1 . The more detailed parameters can also be seen in Ref.  [12] . The alloys with nominal compositions of SmCo 7 , SmCo 6.9 Hf 0.1 , SmCo 6.9 Hf 0.1 (CNTs) 0.05 , SmCo 6.9 Hf 0.1 (CNTs) 0.1 were prepared from high purity (99.99%) elements and Carbon Nanotubes by arc melting in a high purity argon atmosphere. Before arc melting 8% extra Sm was added to the sample to compensate for the weight loss due to Sm vaporization. The ingots were then rapidly solidified by melt spinning in high purity argon at a chamber pressure of 0.6 × 10 5 Pa and a molybdenum wheel velocity of 40 m/s. The ribbon thickness was determined with a TT260 coating-thickness gauge. The samples were analyzed by Rigaku Dmax 2500 Pc X-ray diffractometer with Cu K a radiation and a graphite monochromator. The microstructures and compositions were observed by Philips Tecnai F20 and JEM-2010 transmission electron microscope (TEM) and Philips XL30w/TMP scanning electron microscope (SEM). The magnetic measurements were made by Lake Shore 7407 vibrating sample magnetometer (VSM) with maximum field of 20 kOe and Quantum Design physical properties measurement system (PPMS) with a maximum magnetic field of 90 kOe. 3 Results and discussion 3.1 As-cast alloy SmCo 7 , SmCo 6.9 Hf 0.1 , SmCo 6.9 Hf 0.1 (CNTs) 0.05 and SmCo 6.9 Hf 0.1 (CNTs) 0.1 as-cast alloys were all prepared by arc-melting, and no heat treatment process was carried out before XRD analysis. From the XRD pattern of Fig. 2 a and its magnified pattern of Fig. 2 a2 it can be seen that pure 1:7 Sm–Co as-cast alloy consists of SmCo 5± x main phase, including CaCu 5 -type SmCo 5 phase (for short 1:5H) and TbCu 7 -type SmCo 7 phase (for short 1:7H), as well as small amount of hexagonal Th 2 Ni 17 -type Sm 2 Co 17 phase (for short 2:17H). The SmCo 1:7H type structure is regarded as a derivation of the SmCo 5 type structure through the disordered substitution of the Co–Co dumbbell pair for the Sm [3,8,13] . When solidified from liquid state, SmCo 7 alloy should decompose according to equilibrium crystallization equation: SmCo 7 → SmCo 5 + Sm 2 Co 17 [3,14] . However, when alloys are melted by arc furnace, the cooling rate is actually somewhat faster than that of equilibrium crystallization due to the adoption of circulating water-cooling copper crucible. Therefore, along with the formation of SmCo 5 main phase and Sm 2 Co 17 minor phase, a large amount of SmCo 7 phase remains. In addition, Sm 2 Co 17 maintains 2:17H structure as if in high temperature environment, rather than Th 2 Zn 17 -type 2:17R structure under room temperature. When adding Hf with atomic ratio of 0.1 into SmCo 6.9 alloy, the main phase transforms into 1:7H Sm(Co,Hf) 7 and small amount of 1:5H SmCo 5 phase. Sm 2 Co 17 phase can hardly be found, whereas small amount of HfCo 2 new phase is formed ( Fig. 2 b). Actually we have found the diffraction peaks of HfCo 6 phase which corresponds to the information of PDF No. 330423, but the compound HfCo 6 reported in the literature [15,16] is proved to be non-existent. In NdCo 7− x Hf x system [17] , a trace amount of unknown phase also appeared in each as-cast alloy, and the authors believed the unknown impurity coming from the Nd used as starting material was responsible for it. But these uncertain diffraction peaks are only found in SmCo 6.9 Hf 0.1 alloy in Fig. 2 b. So they are hard to be identified as an accurate phase. Anyway, it can be learned that Hf can stabilize 1:7H structure and restrict the formation of 1:5 and 2:17 phases, which is consistent with the results reported by Guo and his coworkers [4–6] . On the other hand, it indicates that the chemical affinity between Hf and Co is higher than that between Hf and Sm, so no Sm–Hf new phases are formed. Fig. 2 c shows the XRD pattern of SmCo 6.9 Hf 0.1 (CNTs) 0.05 . The main phase is 1:7H Sm(Co,Hf) 7 , whereas 2:17 Sm–Co phase and HfCo 2 are not found. However, small amount of SmCo 5 may exist because there is no separation between 200 and 111 diffraction peaks of 1:7H, which can be caused by the overlap of 200 and 111 diffraction peaks of SmCo 5 phase. It should be noted that small amount of HfC new phase is formed in the alloy. Moreover, the diffraction peaks of pure CNTs are not found, which indicates that CNTs are combined with other elements. By making a comparison between Fig. 2 b and Fig. 2 c, we found that the diffraction peaks of Sm(Co,Hf) 7 phase in SmCo 6.9 Hf 0.1 (CNTs) 0.05 show no signs of left shift compared with those in SmCo 6.9 Hf 0.1 , implying that CNTs do not enter into 1:7H phase as interstitial atoms. Therefore, CNTs mainly combine with Hf to form Hf(CNTs), which shares the same structure with HfC. This is quite different from what was reported in Ref.  [18] : a carbide phase never shows in Sm x (Co 1− y M y ) 100− x − z C z even with 6% of C. However, one thing in common is that C does not enter into the main phase. The electronegativities of C, Co, Sm and Hf are 2.50, 1.70, 1.07 and 1.23, respectively [6] . The elements with larger electronegativity difference prefer to combine together, thus the affinities to form ionic bond, from big to small, are Sm–C(1.43), Hf–C(1.27), Hf–Co(0.47) and Hf–Sm(0.16). However, no Sm–C compounds are found in SmCo 6.9 Hf 0.1 (CNTs) 0.05 , which is different from the results reported by Chang [11] , that is, Sm 2 C 3 is formed in Sm–Co–Hf–C mixtures. The reason may be that CNTs are adopted in this paper, while in Chang's work, it is C to add into the alloy. Also, it may be because the chemical affinity of Hf(CNTs) is higher than that of Sm–CNTs. What is more, our result is different from that in Ref.  [19] . No Co 11 Sm 5 C 2 or CoSmC 2 is found here. Those are also the reasons why CNTs addition and graphite (C) addition can cause different results, so we keep this expression form of CNTs in all alloys and phases. After the addition of CNTs with atomic ratio of 0.1 into SmCo 6.9 Hf 0.1 alloy (see Fig. 2 d), its phase compositions have no difference with that of SmCo 6.9 Hf 0.1 (CNTs) 0.05 , while Hf(CNTs) content grows higher. It is clear that CNTs addition can stabilize 1:7H structure and restrict the formation of other Sm-Co phases. Fig. 3 shows the back scattering electron (BSE) images and component analysis corresponding to the four types of as-cast alloys in Fig. 2 . It can be seen from Fig. 3 a that there are two phases in SmCo 7 alloy and their contrasts are obviously different. According to the principle of atomic number contrast and energy dispersive spectroscopy (EDS) analysis, it can be concluded that the gray area is SmCo 5 phase, while the dark gray area is SmCo 7 and small amount of Sm 2 Co 17 . In the SmCo 6.9 Hf 0.1 alloy showed in Fig. 3 b, gray area is main phase Sm(Co,Hf) 7 and small amount of SmCo 5 , and the white bright zone on the grain boundaries should be HfCo 2 . Because the average atomic number of HfCo 6 is only slightly higher than that of the SmCo 5 , HfCo 2 should be the dominant phase in the grain boundies, which is also consistent with Fig. 2 b. So some of Hf atoms substitute for Co and form Sm(Co,Hf) 7 main phase, and the residual are expelled to the grain boundaries to form HfCo 2 . In the SmCo 6.9 Hf 0.1 (CNTs) 0.05 ( Fig. 3 c), the main phase is gray Sm(Co,Hf) 7 and the white bright area is Hf(CNTs). What is different from that showed in Fig. 3 b is the white bright area of HfCo 2 is distributed on grain boundaries as irregular strip and block, whereas Hf(CNTs) is distributed as discontinuous punctuates in a more dispersive manner in grain boundaries. As the atomic ratio of CNTs increase to 0.1 ( Fig. 3 d), the white bright areas grow larger, indicating that the proportion of Hf(CNTs) phase increases with CNTs, which is consistent with the XRD results in Fig. 2 . In addition, also note that CNTs seize Hf in HfCo 2 to form new dispersive grain boundary phase rather than dissolving into Sm(Co,Hf) 7 structure. The black points in these images are all produced during samples polishing. The energy spectrums ( Fig. 3 a2–d2) and corresponding composition show that the Sm content is a little higher than norminal composition and C content is lower than its norminal composition. However, the redundant Sm can be evaporated during the following melt-spun process. The lower C content is due to the imprecise analysis by EDS because the C atomic number is smaller. 3.2 Melt-spun ribbons Fig. 4 shows the XRD patterns of the ribbons corresponding to the four types of as-cast alloys in Fig. 2 . It can be seen that the ribbons with different compositions all consist of nearly single TbCu 7 -type Sm(Co,Hf) 7 phase, and the diffraction peaks of other phases, such as SmCo 5 , Sm 2 Co 17 , Sm 2 C 3 and pure CNTs, can hardly be found. HfCo 2 can still be found in SmCo 6.9 Hf 0.1 ribbon, as shown in Fig. 4 b. But in SmCo 6.9 Hf 0.1 (CNTs) 0.05 and SmCo 6.9 Hf 0.1 (CNTs) 0.1 ribbons shown in Fig. 4 c and d, the Hf(CNTs) phase is not so clear, implying that melt-spun treatment can restrain the formation of impurity phases, except for TbCu 7 -type phase. Meanwhile, it indicates that the key factor of forming TbCu 7 -type phase in Sm–Co matrix melt-spun ribbons is the melt-spun process, rather than addition elements. If cooled at the speed of 40 m/s, nearly single TbCu 7 -type phase can be formed, even if no other elements are added. In addition, the diffraction peaks in Fig. 4 c and d show no signs of left shift compared with Fig. 4 b, also indicating that CNTs still do not enter Sm(Co,Hf) 7 structure, but rather form other phase. On the other hand, in spite of the fast cooling rate, the diffraction peaks are very sharp in spite of a slightly broadened bottom, which indicates that the content of amorphous phase is low, and it is the amorphous state of Sm(Co,Hf) 7 phase. At 2 θ = 26.5°, all ribbons have a small diffraction peak, which is not be indexed, maybe it is induced by trace amount of oxidation during the second melting. Fig. 5 shows the TEM images of typical regions for the four alloys. Only TbCu 7 -type grains are found in SmCo 7 ribbon ( Fig. 5 a). The grains are unequal in size, and are determined as 150–450 nm approximately. There are no obvious grain boundary phase due to the direct-contact grains. The microstructure of SmCo 6.9 Hf 0.1 ribbon ( Fig. 5 b) has the complete similitude with that of SmCo 7 . Furthermore, the size of some of the largest grains is approximately 100 nm. A few amounts of second phase, which are supposed to be constituted by HfCo 2 , are discovered in part of grain boundaries and grain interior. Therefore, the addition of Hf is not so helpful in grain refinement. The grains in SmCo 6.9 Hf 0.1 (CNTs) 0.05 ribbons ( Fig. 5 c) also behave TbCu 7 -type structure. The grain size is also between 150–450 nm, whereas a new phase is found on grain boundaries. Fig. 5 d shows the magnified grain boundary areas, it has been shown that the boundaries, which consist of extremely fine string-shape grains, has a width about several tens of nanometer. In addition, compared with the alloys without CNTs addition (shown in Fig. 5 a), it is clear that CNTs and this grain boundary phase have no significant effects in refining grain size. The grain boundary phase becomes more obvious with the increase of CNTs content. It can be seen in Fig. 5 e that the grain size of SmCo 6.9 Hf 0.1 (CNTs) 0.1 ribbons ranges from 250 nm to 450 nm, and obvious grain boundary phase can be found all along the grain boundaries. From the local amplification of Fig. 5 f, it can be seen that the width of grain boundary is about 100 nm. As we all know, C content cannot be accurately investigated by EDS, so the composition of this new phase cannot be precisely determined. However, in order to qualitatively determine the compositions of grain boundaries and internal grains in Fig. 5 f, EDS is still used. C is hardly found in internal grains while it is expected to exist on grain boundaries. Hf is distributed both in boundaries and internal grains. Thus, the grains should consist of nearly pure Sm(Co,Hf) 7 main phase. It should also be noted that the contents of Sm and Co on grain boundaries and grain interior show little differences. As discussed above, the Hf(CNTs) phase in SmCo 6.9 Hf 0.1 (CNTs) 0.05 and SmCo 6.9 Hf 0.1 (CNTs) 0.1 ribbons in Fig. 4 c and d is not so obvious. Only TbCu 7 -type diffraction peaks are presented. Thus it is assumed that Hf(CNTs) and part of Sm(Co,Hf) 7 in as-cast alloy become Sm–Co–Hf–(CNTs) melts by remelting, and after melt-spun, the melts transform into a specific grain boundary phase Sm(Co,Hf) 7 (CNTs) x with TbCu 7 structure. Certainly, the possibility of the existence of Hf(CNTs) should not be excluded. Nevertheless, even if there exists, the content must be very low. The CNTs mentioned here are probably C elements, but if they are graphite, the morphology is quite different from that reported in [11,20,21] . So here we still interpret it as CNTs, whereas its accurate status demands further investigations. The formation of an intergranular phase can effectively isolate the hard magnetic Sm(Co,Hf) 7 grains from one another and reduce magnetic interactions, which is similar to the role of Nb and C in the reference [22] . 3.3 Analysis of magnetic properties Fig. 6 A shows the demagnetization curves of ribbons with different compositions under a field of 20 kOe. The ribbons were all melt-spun at 40 m/s and magnetized by a 50 kOe pulsed magnetic field prior to the VSM measurement. To make our results more compellent, we carried out a comparative investigation on SmCo 6.9 Hf 0.1 (CNTs) 0.05 ribbon samples. One sample was magnetized by a 50 kOe pulsed magnetic field followed by VSM measurement under the maximum magnetic field of 20 kOe; The control sample was unmagnetized and directly measured by PPMS under the maximum magnetic field of 90 kOe. The results can be seen in Fig. 6 B and C. It can be learned that the coercivity and remanence of each sample display tiny differences compared with each other. In addition, the sample was not magnetized to saturation even under a magnetic field of 90 kOe. Therefore, considering the cost of measurement, we adopt the data derived from VSM for our study. With the addition of Hf and CNTs, the coercivity and remanence of the ribbons both increase (see Fig. 6 A). Pure SmCo 7 ribbons display the worst magnetic properties. H ci of SmCo 6.9 Hf 0.1 ribbons with Hf addition increase from 2.66 kOe to 3.94 kOe, and M r , M 2T (the magnetization measured under the field of 20 kOe) and remanence ratio M r /M 2T increase from 17.24 emu/g, 56.37 emu/g and 0.31 to 27.68 emu/g, 62.97 emu/g and 0.44, respectively. Adding extra CNTs to the ribbons with Hf can enhance the magnetic properties more significantly. The comprehensive magnetic properties of SmCo 6.9 Hf 0.1 (CNTs) 0.05 ribbons are H ci = 13.95 kOe, M r = 48.85 emu/g, M 2T = 61.09 emu/g and M r /M 2T = 0.80. However, excessive addition of CNTs cause the magnetic properties of SmCo 6.9 Hf 0.1 (CNTs) 0.1 ribbons worse than that of SmCo 6.9 Hf 0.1 C 0.05 ribbons, which are listed as follows: H ci = 6.27 kOe, M r = 37.45 emu/g, M 2T = 69.98 emu/g and M r /M 2T = 0.54. We can see both Hf and CNTs additions can increase the magnetic moment of SmCo 7 alloys. Because the electronegativity of Hf is lower than that of Co, Hf tends to occupy 2e sites preferentially and substitute for some of Co atoms [4] . Generally, Hf can be visualized as nonmagnetic element, so the saturation magnetization should decrease with increasing content of the doping element [6] . What is hard to explain is that the moment of SmCo 6.9 Hf 0.1 during magnetization is higher than that of pure SmCo 7 all along. The anisotropy field of the ribbons will increase because of Hf's occupation of 2e sites, so the coercivity of TbCu 7 -type SmCo 6.9 Hf 0.1 would be higher than that of pure SmCo 7 [6] . The magnetization is also increased with CNTs addition, whereas coercivity increases more significantly, especially in SmCo 6.9 Hf 0.1 (CNTs) 0.05 ribbons. Though the ferromagnetism of CNTs is an open and controversial subject, Stamenovn [23] has proposed that CNTs can display weak ferromagnetism, and their anisotropy and magnetization change with orientation. In addition, their orbital magnetic moment can approach as high as 10-20 μ B . The enhancement of magnetization may be caused by the combined action of CNTs and Hf, Sm as well as Co. From the analysis above, CNTs do not dissolve to grains, but rather form grain boundary phase, such as Sm(Co,Hf) 7 (CNTs) x , which should be a new ferromagnetic phase that is different from intragranular Sm(Co,Hf) 7 , and such phase can be constituted by 10 nm or bigger grains. If CNTs content is at a proper level and distributed uniformly on the grain boundaries, the Sm(Co,Hf) 7 (CNTs) x can serve the similar role as Sm(Co,Cu) 5 cell boundary phase in traditional Sm–Co–Cu–Fe–Zr sintered magnets, and increasingly significant pinning effect can be obtained. Meanwhile, the intergranular magnetic interaction is also strong, which result in increasing coercivity and remanence ratio, for example, the M r /M 2T of SmCo 6.9 Hf 0.1 (CNTs) 0.05 can reach 0.8. However, if CNTs content is too high, such as SmCo 6.9 Hf 0.1 (CNTs) 0.1 ribbons, CNTs would excessively accumulate on grain boundaries, resulting in decrease of magnetic exchange interaction between Sm(Co,Hf) 7 grains, and ultimately decrease coercivity, as well as Mr/M 2T to 0.54. 4 Conclusions SmCo 7 , SmCo 6.9 Hf 0.1 , SmCo 6.9 Hf 0.1 (CNTs) 0.05 , and SmCo 6.9 Hf 0.1 (CNTs) 0.1 as-cast alloys and ribbons melt-spun at 40 m/s are prepared, and effects of Hf and CNTs on phase composition, microstructure and magnetic properties of as-cast alloys and ribbons are studied. It can be concluded as follows: (1) SmCo 7 as-cast alloys consist of SmCo 5 and SmCo 7 main phase and small amount of Sm 2 Co 17 . SmCo 6.9 Hf 0.1 alloy consists of Sm(Co,Hf) 7 main phase, small amount of SmCo 5 phase and HfCo 2 grain boundary phase. SmCo 6.9 Hf 0.1 (CNTs) 0.05 and SmCo 6.9 Hf 0.1 (CNTs) 0.1 alloys both consist of Sm(Co,Hf) 7 main phase, small amount of 1:5H and fine dispersed Hf(CNTs) grain boundary phase. (2) Four types of ribbons with different compositions all consist of TbCu 7 -type Sm(Co,Hf) 7 main phase. The grains are unequal in size, and are determined as 150–450 nm approximately. Cooling rate of the ribbons is the key factor of forming TbCu 7 -type phase. The content of amorphous phase in all ribbons is low. (3) There is no grain boundary phase in SmCo 7 ribbon due to the direct-contact SmCo 7 grains. HfCo 2 may also be distributed in Sm(Co,Hf) 7 grain interior. The grain boundaries of ribbons with CNTs addition mainly consist of a specific grain boundary phase, which is assumed to have similar TbCu 7 structure with the intragranular phase and its composition is Sm(Co,Hf) 7 (CNTs) x . (4) The coercivity, remanence and remanence ratio M r /M 2T of the ribbons all increase with Hf and CNTs additions. The comprehensive magnetic properties of SmCo 6.9 Hf 0.1 (CNTs) 0.05 ribbons are H ci = 13.95 kOe, M r = 48.85 emu/g, M 2T = 61.09 emu/g and M r /M 2T = 0.80. Excessive CNTs addition may worsen the magnetic properties. Acknowledgement This work is supported by Tianjin Natural Science Foundation of China (09JCZDJC22800). And part of work is supported by Doctoral Fund of Ministry of Education of China (No. 20060080005). References [1] R.T. Fingers C.S. Rubertus Application of high temperature magnetic materials IEEE Trans Magn 36 2000 3373 3375 [2] J.F. Liu Y. Zhang D. Dimitrov G.C. Hadjipanayis Microstructure and high temperature magnetic properties of Sm(Co, Cu, Fe, Zr) z (z = 6.7–9.1) permanent magnets J Appl Phys 85 1999 2800 2804 [3] Y.Q. Guo W. Li W.C. Feng J. Luo J.K. Liang Q.J. He Structural stability and magnetic properties of SmCo 7−x Ga x Appl Phys Lett 86 2005 192513 192523 [4] Y.Q. Guo W. Li J. Luo W.C. Feng J.K. Liang Structure and magnetic characteristics of novel SmCo-based hard magnetic alloys J Magn Magn Mater 303 2006 e367 e370 [5] Y.Q. Guo W.C. Feng W. Li J. Luo J.K. Liang Magnetism and phase stability of R(Co, M) 7 pseudobinary intermetallics with TbCu 7 -type structure J Appl Phys 101 2007 023919 023927 [6] J. Luo J.K. Liang Y.Q. Guo Q.L. Liu F.S. Liu Y. Zhang Effects of the doping element on crystal structure and magnetic properties of Sm(Co, M) 7 compounds (M = Si, Cu, Ti, Zr, and Hf) Intermetallics 13 2005 710 716 [7] T. Liu W. Li X.M. Li W.C. Feng Y.Q. Guo Crystal structure and magnetic properties of SmCo 7−x Ag x J Magn Magn Mater 310 2007 e632 e634 [8] S. Aich J. Kostogorova J.E. Shield Magnetic behavior of Sm-Co-based permanent magnets during order/disorder phase transformations J Appl Phys 97 2005 10H108–3 [9] S. Aich J.E. Shield Effect of Nb and C additives on the microstructures and magnetic properties of rapidly solidified Sm–Co alloys J Alloys Compd 425 2006 416 423 [10] D.T. Zhang M. Yue J.X. Zhang L.J. Pan Bulk nanocrystalline SmCo 6.6 Nb 0.4 sintered magnet with TbCu 7 -type Structure prepared by spark plasma sintering IEEE Trans Magn 43 2007 3494 3496 [11] H.W. Chang S.T. Huang C.W. Chang C.H. Chiu W.C. Chang A.C. Sun Magnetic properties, phase evolution, and microstructure of melt spun SmCo 7-x Hf x C y (x = 0–0.5; Y = 0–0.14) ribbons J Appl Phys 101 2007 09K508-3 [12] http://www.billnt.com/chanpin.htm [13] S. Derkaoui N. Valignat C.H. Allibert Phase equilibria at 1150 °C in the Co-rich alloys Sm–Co–Zr and structure of the 1:7 phase J Alloys Compd 232 1996 296 301 [14] M.B. Tian Magnetic material 2001 Tsinghua University Press Beijing p.111 [15] K.H.J. Buschow J.H. Wernick G.Y. Chin Note on the Hf–Co phase diagram J Less Common Metals 59 1978 61 67 [16] K.C. Chen E.J. Peterson D.J. Thoma HfCo 2 Laves phase intermetallics-part I: solubility limits and defect mechanisms Intermetallics 9 2001 771 783 [17] J. Luo J.K. Liang Y.Q. Guo Q.L. Liu F.S. Liu L.T. Yang Phase stability, crystal structure, and magnetic properties of NdCo 7−x Hf x compounds Phys B Condens Matter 353 2004 98 103 [18] D. Sultana A.M. Gabay G.C. Hadjipanayis High performance isotropic Sm–(Co, Fe)–C and Sm–(Co, Fe, Mn)–C magnets by melt spinning J Appl Phys 103 2008 07E125-3 [19] H.H. Stadelmaier N.C. Liu Ternary system cobalt-samarium-carbon Zeitschrift fuer Metallkunde 76 1985 585 588 [20] H.W. Chang S.T. Huang C.W. Chang W.C. Chang A.C. Sun Y.D. Yao Effect of C addition on the magnetic properties, phase evolution, and microstructure of melt spun SmCo 7−x Hf x (x = 0.1–0.3) ribbons Solid State Commun 147 2008 69 73 [21] H.W. Chang S.T. Huang C.W. Chang C.H. Chiu I.W. Chen W.C. Chang Effect of additives on the magnetic properties and microstructure of melt spun SmCo 6.9 Hf 0.1 M 0.1 (M = B, C, Nb, Si, Ti) ribbons J Alloys Compd 455 2008 506 509 [22] S. Aich V.K. Ravindran J.E. Shield Highly coercive rapidly solidified Sm–Co alloys J Appl Phys 99 2006 08B521 [23] P. Stamenov J.M.D. Coey Magnetic susceptibility of carbon-experiment and theory J Magn Magn Mater 290–291 2005 279 285",
        "keywords": [
            "A. Rare-earth intermetallics",
            "B. Magnetic properties",
            "C. Rapid solidification processing",
            "D. Microstructure"
        ],
        "authors": [
            {
                "name": "Ji-bing Sun",
                "org": ""
            },
            {
                "name": "Dan Han",
                "org": "School of Material Science and Engineering, Hebei University of Technology, Dingzigu Road, Hongqiao District, Tianjin 300130, PR China"
            },
            {
                "name": "Chun-xiang Cui",
                "org": "School of Material Science and Engineering, Hebei University of Technology, Dingzigu Road, Hongqiao District, Tianjin 300130, PR China"
            },
            {
                "name": "Wei Yang",
                "org": "School of Material Science and Engineering, Hebei University of Technology, Dingzigu Road, Hongqiao District, Tianjin 300130, PR China"
            },
            {
                "name": "Liang Li",
                "org": "School of Material Science and Engineering, Hebei University of Technology, Dingzigu Road, Hongqiao District, Tianjin 300130, PR China"
            },
            {
                "name": "Fan Yang",
                "org": "School of Material Science and Engineering, Hebei University of Technology, Dingzigu Road, Hongqiao District, Tianjin 300130, PR China"
            },
            {
                "name": "Li-guo Yang",
                "org": "School of Material Science and Engineering, Hebei University of Technology, Dingzigu Road, Hongqiao District, Tianjin 300130, PR China"
            }
        ],
        "venue": "Intermetallics",
        "year": 2010
    },
    "wG9ZyYv6": {
        "id": "wG9ZyYv6",
        "title": "Electrochemical fabrication and magnetic properties of Fe7Co3 alloy nanowire array",
        "abstract": "",
        "keywords": [
            "nanowires",
            "aqueous solution",
            "magnetic anisotropy",
            "magnetic materials",
            "microstructures",
            "magnetic properties"
        ],
        "authors": [
            {
                "name": "jian yang",
                "org": "hebei university of technology"
            },
            {
                "name": "chunxiang cui",
                "org": "hebei university of technology"
            },
            {
                "name": "wei yang",
                "org": "hebei university of technology"
            },
            {
                "name": "bing hu",
                "org": "hebei university of technology"
            },
            {
                "name": "jibing sun",
                "org": "hebei university of technology"
            }
        ],
        "venue": "Journal of Materials Science",
        "year": 2010
    },
    "wAN84hmD": {
        "id": "wAN84hmD",
        "title": "Effects of melt-spinning speed on microstructure and crystallization procedure of Nd10Fe81Co3B6 ribbons",
        "abstract": "Melt-spinning speed has a significant effect on the microstructure and properties of melt-spinning Nd-Fe-B ribbons. In this paper, Nd10Fe81Co3B6 ribbons were prepared by melt-spinning method with different melt-spinning speeds, and the effects of melt-spinning speeds on the phase structure and crystallization procedure of Nd10Fe81Co3B6 ribbons were studied. The results show that there are great differences in the content of amorphous phases under different melt-spinning speeds. When the melt-spinning speed was increased, the content of amorphous phase was also increased. Moreover, the crystallization processes of ribbons melt-spun at different speeds are different. When the melt-spinning speed was low, there was a high degree of crystallization phase, whose crystallization annealing was controlled by disperse particle nucleus; with increasing the melt-spinning speed, there was high content of amorphous phase, whose crystallization annealing was gradually controlled by continuous crystallization model. With increasing melt-spinning speeds from 15 to 50m/s, the beginning crystallization temperature of all ribbons was at the range of 540-610°C.",
        "keywords": [
            "Crystallization procedure",
            "Melt-spinning speed",
            "Microstructure",
            "Nanocomposite magnets"
        ],
        "authors": [
            {
                "name": "Ruiping Ping Han",
                "org": "Hebei University of Technology(Hebei University of Technology),Tianjin,China"
            },
            {
                "name": "Chunxiang Cui",
                "org": "Hebei University of Technology(Hebei University of Technology),Tianjin,China"
            },
            {
                "name": "Jibing Sun",
                "org": "Hebei University of Technology(Hebei University of Technology),Tianjin,China"
            },
            {
                "name": "Wei Yang",
                "org": "Hebei University of Technology(Hebei University of Technology),Tianjin,China"
            }
        ],
        "venue": "Gongneng Cailiao/Journal of Functional Materials",
        "year": 2010
    },
    "d9w5LxrH": {
        "id": "d9w5LxrH",
        "title": "Fabrication and magnetic properties of Fe3Co7 alloy nanowire arrays",
        "abstract": "Fe3Co7 alloy nanowire arrays have been fabricated by direct current electrodeposition of Fe2+ and Co2+ into anodic aluminum oxide (AAO) templates. The phase structure and magnetic properties of the nanowires were studied by transmission electron microscopy (TEM), scanning electron microscopy (SEM), X-ray diffraction (XRD), and vibrating sample magnetometer (VSM). Magnetic measurements show that the coercivity and remanence of the as-deposited Fe3Co7 Alloy nanowires increase dramatically after heat-treatment at 773 K for 2 h, and the nanowire arrays exhibit uniaxial magnetic anisotropy with easy magnetization direction along the nanowire axes owing to the large shape anisotropy. The great difference between practical coercivity and ideal coercivity was also discussed in detail. © 2009 Springer Science+Business Media, LLC.",
        "keywords": [
            "Anodic Aluminum Oxide",
            "Vibrate Sample Magnetometer",
            "Nanowire Array",
            "Anodic Aluminum Oxide Template",
            "Oxalic Acid Solution"
        ],
        "authors": [
            {
                "name": "Wei Yang",
                "org": "Hebei University of Technology(Hebei University of Technology),Tianjin,China"
            },
            {
                "name": "Chunxiang Cui",
                "org": "Hebei University of Technology(Hebei University of Technology),Tianjin,China"
            },
            {
                "name": "Jibing Sun",
                "org": "Hebei University of Technology(Hebei University of Technology),Tianjin,China"
            },
            {
                "name": "Baoli Wang",
                "org": "Hebei University of Technology(Hebei University of Technology),Tianjin,China"
            }
        ],
        "venue": "Journal of Materials Science",
        "year": 2010
    },
    "jaxkQ9Dc": {
        "id": "jaxkQ9Dc",
        "title": "Fabrication and magnetic properties of Fe<sub>3</sub>Co<sub>7</sub> alloy nanowire arrays",
        "abstract": "Fe3Co7 alloy nanowire arrays have been fabricated by direct current electrodeposition of Fe2+ and Co2+ into anodic aluminum oxide (AAO) templates. The phase structure and magnetic properties of the nanowires were studied by\n transmission electron microscopy (TEM), scanning electron microscopy (SEM), X-ray diffraction (XRD), and vibrating sample\n magnetometer (VSM). Magnetic measurements show that the coercivity and remanence of the as-deposited Fe3Co7 Alloy nanowires increase dramatically after heat-treatment at 773 K for 2 h, and the nanowire arrays exhibit uniaxial magnetic\n anisotropy with easy magnetization direction along the nanowire axes owing to the large shape anisotropy. The great difference\n between practical coercivity and ideal coercivity was also discussed in detail.",
        "keywords": [
            "x ray diffraction",
            "transmission electron microscopy",
            "magnetic anisotropy",
            "nanowires",
            "magnetic properties",
            "scanning electron microscopy",
            "heat treatment"
        ],
        "authors": [
            {
                "name": "Wei Yang",
                "org": "Hebei University of Technology School of Materials Science and Engineering No. 129 Guangrong Road, Hongqiao District Tianjin 300130 People’s Republic of China"
            },
            {
                "name": "Chunxiang Cui",
                "org": "Hebei University of Technology School of Materials Science and Engineering No. 129 Guangrong Road, Hongqiao District Tianjin 300130 People’s Republic of China"
            },
            {
                "name": "Jibing Sun",
                "org": "Hebei University of Technology School of Materials Science and Engineering No. 129 Guangrong Road, Hongqiao District Tianjin 300130 People’s Republic of China"
            },
            {
                "name": "Baoli Wang",
                "org": "Hebei University of Technology School of Materials Science and Engineering No. 129 Guangrong Road, Hongqiao District Tianjin 300130 People’s Republic of China"
            }
        ],
        "venue": "Journal of Materials Science",
        "year": 2010
    },
    "smcu3iL5": {
        "id": "smcu3iL5",
        "title": "Effects of melt-spinning speed on microstructure and magnetic properties of Nd 10Fe 81Co 3B 6 ribbons",
        "abstract": "Nd 10Fe 81Co 3B ribbons were prepared by melt-spinning method at different melt-spinning speeds, and the effects of melt-spinning speeds on the microstructure and magnetic properties of Nd 10Fe 81Co 3B ribbons were studied. The results show that the content of amorphous phase is increased with increasing the melt-spinning speed. After annealed at 800°C for 10 min, the ribbons melt-spun at 15 m/s speeds are consisted of Nd 2(Fe, Co) 14B and Fe 7Co 3. The medium grain size of Nd 2(Fe, Co) 14B is greater than 50 nm, however that of Fe 7Co 3 size is smaller than 25 nm. Inter-grains exchange coupling interaction is weakened; there are high content of amorphous phase in the ribbons melt-spun at 50 m/s, which makes the remanence reduce, and the coercivity didn't obviously reduce. The ribbons melt-spun at 50 m/s had a optimum crystallization, and the inter-grains exchange coupling interaction acted well. Their magnetic properties are H c=249 928 A/m, M r=84.3 A·m 2/kg. Furthermore, Curie temperature of the ribbons with different melt-spinning speeds are basically same, it's about 630 K. Copyright© 2011, Northwest Institute for Nonferrous Metal Research. Published by Elsevier BV.All rights reserved.",
        "keywords": [
            "Magnetic properties",
            "Melt-spinning speed",
            "Microstructure"
        ],
        "authors": [
            {
                "name": "Ruiping Ping Han",
                "org": "Hebei University of Technology(Hebei University of Technology),Tianjin,China"
            },
            {
                "name": "Chunxiang Cui",
                "org": "Hebei University of Technology(Hebei University of Technology),Tianjin,China"
            },
            {
                "name": "Jibing Sun",
                "org": "Hebei University of Technology(Hebei University of Technology),Tianjin,China"
            },
            {
                "name": "Wei Yang",
                "org": "Hebei University of Technology(Hebei University of Technology),Tianjin,China"
            }
        ],
        "venue": "Xiyou Jinshu Cailiao Yu Gongcheng/Rare Metal Materials and Engineering",
        "year": 2011
    },
    "fmYmvgc4": {
        "id": "fmYmvgc4",
        "title": "Electrochemical fabrication and magnetic properties of Fe 7Co3 alloy nanowire array",
        "abstract": "A new type of magnetic material, Fe7Co3 nanowires, was successfully synthesized for the first time via a simple electrodeposition method. Highly uniform, self-ordered porous anodic aluminum oxide (AAO) membranes were prepared by the way of electrochemical. Fe7Co 3 alloy nanowire arrays were fabricated in the porous alumina template in an aqueous solution of FeCl2 and CoCl2 by direct current electrodepositing. The microstructures of nanowires and AAO template were characterized by XRD, SEM, and TEM. The results show that a single Fe7Co3 nanowire is 40 nm in width and 2.5 μm in length with a preferred crystal face (110) during growing. The Fe7Co 3 nanowire arrays have uniaxial magnetic anisotropy with easy magnetization direction along the nanowire axis due to the large shape anisotropy. It also shows that Fe7Co3 nanowire is a well-soft magnetic phase compared with Fe nanowires. It illustrates that Fe 7Co3 possess higher saturation magnetization. © 2010 Springer Science+Business Media, LLC.",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Jian Yang",
                "org": "Hebei University of Technology(Hebei University of Technology),Tianjin,China"
            },
            {
                "name": "Chunxiang Cui",
                "org": "Hebei University of Technology(Hebei University of Technology),Tianjin,China"
            },
            {
                "name": "Wei Yang",
                "org": "Hebei University of Technology(Hebei University of Technology),Tianjin,China"
            },
            {
                "name": "Bing Hu",
                "org": "Hebei University of Technology(Hebei University of Technology),Tianjin,China"
            },
            {
                "name": "Jibing Sun",
                "org": "Hebei University of Technology(Hebei University of Technology),Tianjin,China"
            }
        ],
        "venue": "Journal of Materials Science",
        "year": 2011
    },
    "3WwVM0aR": {
        "id": "3WwVM0aR",
        "title": "Electrochemical fabrication and magnetic properties of Fe<sub>7</sub>Co<sub>3</sub> alloy nanowire array",
        "abstract": "A new type of magnetic material, Fe7Co3 nanowires, was successfully synthesized for the first time via a simple electrodeposition method. Highly uniform, self-ordered\n porous anodic aluminum oxide (AAO) membranes were prepared by the way of electrochemical. Fe7Co3 alloy nanowire arrays were fabricated in the porous alumina template in an aqueous solution of FeCl2 and CoCl2 by direct current electrodepositing. The microstructures of nanowires and AAO template were characterized by XRD, SEM, and\n TEM. The results show that a single Fe7Co3 nanowire is 40 nm in width and 2.5 µm in length with a preferred crystal face (110) during growing. The Fe7Co3 nanowire arrays have uniaxial magnetic anisotropy with easy magnetization direction along the nanowire axis due to the large\n shape anisotropy. It also shows that Fe7Co3 nanowire is a well-soft magnetic phase compared with Fe nanowires. It illustrates that Fe7Co3 possess higher saturation magnetization.",
        "keywords": [],
        "authors": [
            {
                "name": "Jian YangChunxiang CuiWei Yang",
                "org": "School of Materials Science & Engineering, Hebei University of Technology, Tianjin, 300130 China"
            },
            {
                "name": "Chunxiang Cui",
                "org": "School of Materials Science & Engineering, Hebei University of Technology, Tianjin, 300130 China"
            },
            {
                "name": "Wei Yang",
                "org": "School of Materials Science & Engineering, Hebei University of Technology, Tianjin, 300130 China"
            },
            {
                "name": "Bing Hu",
                "org": "School of Materials Science & Engineering, Hebei University of Technology, Tianjin, 300130 China"
            },
            {
                "name": "Jibing Sun",
                "org": "School of Materials Science & Engineering, Hebei University of Technology, Tianjin, 300130 China"
            }
        ],
        "venue": "",
        "year": 2011
    },
    "jYGb9o63": {
        "id": "jYGb9o63",
        "title": "Electrodepositing fabrication and microstructures of the Fe nanowires with a preferred orientation",
        "abstract": "Highly ordered Fe nanowire arrays with 〈110〉 preferred orientation were fabricated out successfully by direct current electrodepositing into the pores of a porous anodic aluminum oxide template. The formation mechanism of Fe nanowires was ascertained by X-ray diffraction and transmission electron microscopy. Low index surface energy of Fe nanowires was calculated by means of broken-bond model. For Fe nanowire arrays, its aspect ratio (h/d) of the \"circular cylinder\" is less than 0.75, the {1 1 0} planes have the lowest surface energy. And authors deal with a reasonable explanation for Fe nanowires growth along with 〈110〉 preferred orientation using the two-dimensional nucleation theory. © 2011 Elsevier Ltd. All rights reserved.",
        "keywords": [
            "electrodepositing",
            "nanocrystalline materials",
            "nanocrystalline microstructure",
            "single crystal growth",
            "transmission electron microscopy",
            "x ray diffraction",
            "nanowires",
            "nanocrystalline material",
            "aspect ratio",
            "indexation",
            "surface energy",
            "microstructures"
        ],
        "authors": [
            {
                "name": "Chunxiang Cui",
                "org": "Hebei University of Technology(Hebei University of Technology),Tianjin,China"
            },
            {
                "name": "Wei Yang",
                "org": "Hebei University of Technology(Hebei University of Technology),Tianjin,China"
            },
            {
                "name": "Jibing Sun",
                "org": "Hebei University of Technology(Hebei University of Technology),Tianjin,China"
            },
            {
                "name": "Qingjun Zhang",
                "org": "Hebei Polytechnic University(Hebei Polytechnic University),Tangshan,China"
            }
        ],
        "venue": "Superlattices and Microstructures",
        "year": 2011
    },
    "2FqTlAUV": {
        "id": "2FqTlAUV",
        "title": "Effects of adding different types of carbon on the structure and magnetic properties of SmCo6.9Hf0.1 alloy",
        "abstract": "In this paper, SmCo6.9Hf0.1 as-cast alloys and ribbons with the addition of either graphite (C) or carbon nanotubes (CNTs) were prepared by arc melting and melt-spinning, respectively. The effects of adding carbon on the structure and magnetic properties SmCo6.9Hf 0.1 were investigated by means of X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), magnetic force microscopy (MFM) and vibrating sample magnetometer (VSM). It was found that the microstructure and magnetic structure of SmCo6.9Hf 0.1 ribbons were changed obviously due to the introduction of C or CNTs, although their crystal structure was characterized as the same Sm(Co,Hf)7 single phase, no matter carbon was added or not. As a result, the magnetic properties of carbon-contained ribbons were enhanced in a certain degree. This was considered to be related to the refined equiaxed grains, small domain size and the pinning effect of C or CNTs-rich regions. The magnetic properties of SmCo6.9Hf0.1(CNTs)0.05 ribbons reached Hc=12.5 kOe, Mr=57.0 emu/g and M r/M2 T=0.788. © 2013 The Chinese Society of Rare Earths.",
        "keywords": [
            "magnetically ordered materials rapid-solidification crystal structure magnetic measurements rare earths"
        ],
        "authors": [
            {
                "name": "Jibing Sun",
                "org": "Hebei University of Technology(Hebei University of Technology),Tianjin,China"
            },
            {
                "name": "Shaojing Bu",
                "org": "Hebei University of Technology(Hebei University of Technology),Tianjin,China"
            },
            {
                "name": "Wei Yang",
                "org": "Hebei University of Technology(Hebei University of Technology),Tianjin,China"
            },
            {
                "name": "Hongshui Wang",
                "org": "Hebei University of Technology(Hebei University of Technology),Tianjin,China"
            },
            {
                "name": "Chunxiang Cui",
                "org": "Hebei University of Technology(Hebei University of Technology),Tianjin,China"
            },
            {
                "name": "Chenhui He",
                "org": "Hebei University of Technology(Hebei University of Technology),Tianjin,China"
            }
        ],
        "venue": "Journal of Rare Earths",
        "year": 2013
    },
    "yosa8vYK": {
        "id": "yosa8vYK",
        "title": "The effects of CNTs and/or Si additions on the structure and magnetic properties of SmCo7-based alloys",
        "abstract": "In this work, SmCo7, SmCo7(CNTs)0.05, SmCo6.1Si0.9, SmCo6.1Si0.9(CNTs) 0.05 as-cast ingots and ribbons were prepared by arc-melting and melt-spinning methods respectively. The effects of Si and/or CNTs additions on the structure and magnetic properties of SmCo7-based alloys were investigated. It was found that adding Si into the SmCo7-based as-cast alloys can stabilize the TbCu7-type structure, while CNTs addition facilitates the formation of Th2Zn17-type phase. However, for SmCo7-based ribbons, the cooling rate plays a more significant role in the formation of a single TbCu7-type phase than the doped elements. The coercivity (Hc) and remanence ratio (M r/M2T) of all SmCo7-based ribbons increase with the addition of CNTs and/or Si. In particular, simultaneous addition of CNTs and Si can improve the Hc and Mr/M2T more effectively than that of a single one. On the other hand, the magnetization of SmCo7-based ribbons at high temperature is improved by CNTs addition while decreased by Si addition. At the same time, the thermal stability of ribbons decreases when Si is introduced. The possible mechanism of magnetization reversal in the SmCo7-based ribbons containing Si and/or CNTs is considered to be the combination of nucleation and pinning.© 2013 Elsevier B.V. All rights reserved.",
        "keywords": [
            "Crystal structure",
            "Intermetallics",
            "Magnetic measurements",
            "Rapid-solidification"
        ],
        "authors": [
            {
                "name": "Jibing Sun",
                "org": "Hebei University of Technology(Hebei University of Technology),Tianjin,China"
            },
            {
                "name": "ShaoJing Bu",
                "org": "Hebei University of Technology(Hebei University of Technology),Tianjin,China"
            },
            {
                "name": "Hewei Ding",
                "org": "Hebei University of Technology(Hebei University of Technology),Tianjin,China"
            },
            {
                "name": "Chunxiang Cui",
                "org": "Hebei University of Technology(Hebei University of Technology),Tianjin,China"
            },
            {
                "name": "Wei Yang",
                "org": "Hebei University of Technology(Hebei University of Technology),Tianjin,China"
            },
            {
                "name": "Li Zhang",
                "org": "Hebei University of Technology(Hebei University of Technology),Tianjin,China"
            }
        ],
        "venue": "Journal of Alloys and Compounds",
        "year": 2013
    },
    "55F2kfuE": {
        "id": "55F2kfuE",
        "title": "The effects of CNTs and/or Si additions on the structure and magnetic properties of SmCo 7 -based alloys",
        "abstract": "",
        "keywords": [
            "intermetallics",
            "crystal structure"
        ],
        "authors": [
            {
                "name": "jibing sun",
                "org": ""
            },
            {
                "name": "shaojing bu",
                "org": ""
            },
            {
                "name": "hewei ding",
                "org": ""
            },
            {
                "name": "chunxiang cui",
                "org": ""
            },
            {
                "name": "wei yang",
                "org": ""
            },
            {
                "name": "li zhang",
                "org": ""
            }
        ],
        "venue": "Journal of Alloys and Compounds",
        "year": 2013
    },
    "yNlV0kwB": {
        "id": "yNlV0kwB",
        "title": "Structure and magnetic properties of SmCo7-xGa x (0 �� x �� 1.2) alloys",
        "abstract": "In this article, the effects of Ga addition on the structure and magnetic properties of SmCo7 alloy were studied. The results show that a stable TbCu7-type single phase can be obtained in as-cast SmCo 7-xGax alloys when a proper amount of Ga is introduced (x = 0.9). Meanwhile, all SmCo7-xGax ribbons melt-spun at 40 m/s are composed of single TbCu7-type phase. So both the appropriate doping of Ga, and more especially the rapid cooling rate, can effectively stabilize the TbCu7-type structure. Moreover, Ga addition affects not only the stability and the order degree of 1:7H phase but also the uniformity of nucleation. Magnetic tests reveal that the coercivity, remanence and remanence ratio of the ribbons increase with the Ga addition, and reach their maximum values (7117.0 �� 2081.5 Oe, 36.7 �� 4.2 emu/g and 0.771 �� 0.037, respectively) when x = 0.9. At the same time, the maximum magnetization of ribbons and Curie temperature (T c) of Sm-Co phases tend to decrease with the amount of Ga. In particular, the TbCu7-type phase in SmCo7- xGax ribbons is basically stable below 500 ��C, and the phase transition during the heating process is also discussed. ? 2013 Elsevier B.V. All rights reserved.",
        "keywords": [
            "Intermetallics",
            "Magnetic measurements",
            "Microstructure",
            "Phase transitions",
            "Rapid-solidification"
        ],
        "authors": [
            {
                "name": "Jibing Sun",
                "org": "Hebei University of Technology(Hebei University of Technology),Tianjin,China"
            },
            {
                "name": "Shaojing Bu",
                "org": "Hebei University of Technology(Hebei University of Technology),Tianjin,China"
            },
            {
                "name": "Wei Yang",
                "org": "Hebei University of Technology(Hebei University of Technology),Tianjin,China"
            },
            {
                "name": "Hewei Ding",
                "org": "Hebei University of Technology(Hebei University of Technology),Tianjin,China"
            },
            {
                "name": "Chunxiang Cui",
                "org": "Hebei University of Technology(Hebei University of Technology),Tianjin,China"
            },
            {
                "name": "Hanxiao Zheng",
                "org": "Hebei University of Technology(Hebei University of Technology),Tianjin,China"
            }
        ],
        "venue": "Journal of Alloys and Compounds",
        "year": 2014
    },
    "pRLS0l6p": {
        "id": "pRLS0l6p",
        "title": "A Study of Biogeochemical Characteristics and Nitrogen Transformation of the Saturation Stratum",
        "abstract": "The research aims to study the influence of the higher manganese and iron contents in the phreatic aquifer of quarternary loose stratum on nitrogen transformation in the shallow phreatic aquifer in the Hun River basin.With the environmental hydro-geochemistry theory,the mechanism of the chemical and biological function of iron and manganese on the nitrogen transformation is studied through in-site sampling and laboratory analysis.The geochemical indexes and microbial indicator from the rock samples of saturation zone are measured,which are taken from a depth of 110m near the northern bank of the Xi River,a tributary of the Hun River.The results illustrate that the close relationship between the geochemical indexes and microbial indicators exist with the longitudinal profile of the borehole at the pH of 6.14～6.64,including the peaks and fluctuating sections.The lithologic natures and the local biogeochemical environment have significant effects on the nitrogen transformation,resulting in the higher mass-fraction of ammonium.The research results provide the technological parameters for remediating micro-polluted groundwater and studying the trend of nitrogen transformation in the regional environmental system.",
        "keywords": [
            "saturation stratum",
            "groundwater",
            "ammonium and nitrogon",
            "denitrification",
            "alluvial and flood fan",
            "iron and manganese"
        ],
        "authors": [
            {
                "name": "YANG Wei",
                "org": "School of Municipal and Environmental Engineering,Shenyang Jianzhu University,Shenyang,China,"
            },
            {
                "name": "WANG Yong",
                "org": "School of Municipal and Environmental Engineering,Shenyang Jianzhu University,Shenyang,China,"
            },
            {
                "name": "LI Yubin",
                "org": "Liaoning Academy of Environmental Sciences,Shenyang,China,"
            },
            {
                "name": "PAN Jun",
                "org": "School of Municipal and Environmental Engineering,Shenyang Jianzhu University,Shenyang,China,"
            },
            {
                "name": "YUAN Yashu",
                "org": "School of Municipal and Environmental Engineering,Shenyang Jianzhu University,Shenyang,China,"
            },
            {
                "name": "GUO Yu",
                "org": "School of Municipal and Environmental Engineering,Shenyang Jianzhu University,Shenyang,China,"
            }
        ],
        "venue": "Journal of Shenyang Jianzhu University(Natural Science)",
        "year": 2006
    },
    "AREkz5Gm": {
        "id": "AREkz5Gm",
        "title": "BENTONITE AS A REACTING MEDIUM OF PRB:Current research situation and discussion",
        "abstract": "Based on the introduction to the mineralogical types and characters of bentonite,as well as its modification methods,including acid activation,roasting,inorganic salt adding and organic ammonium salt adding,this paper elaborates the present status of application of this mineral in wastewater treatment,garbage landfill site and amelioration of soils. Using bentonite as a reacting medium of permeable reacting barrier (PRB),the changing situation of groundwater pollution is simulated for landfill filtration liquid,with COD,sexivalent chromium and ammonium as target contaminants. The experiment shows that the pH and DO values have a certain influence on the removal efficiency of target contaminants. The removal rates of COD,sexivalent chromium and ammonium are 53% ,51% and 53% respectively,through the reacting medium. The result suggests the feasibility of bentonite as reacting medium of PRB.",
        "keywords": [
            "bentonite",
            "PRB",
            "reacting medium",
            "target contaminants"
        ],
        "authors": [
            {
                "name": "YANG Wei",
                "org": "College of Municipal and Environmental Engineering,Shenyang University of Architecture,Shenyang ,China"
            },
            {
                "name": "YANG Jun-feng",
                "org": "College of Municipal and Environmental Engineering,Shenyang University of Architecture,Shenyang ,China"
            },
            {
                "name": "WANG Li-dong",
                "org": "College of Municipal and Environmental Engineering,Shenyang University of Architecture,Shenyang ,China"
            },
            {
                "name": "WANG Hu",
                "org": "College of Municipal and Environmental Engineering,Shenyang University of Architecture,Shenyang ,China"
            },
            {
                "name": "GUO Yu",
                "org": "College of Municipal and Environmental Engineering,Shenyang University of Architecture,Shenyang ,China"
            }
        ],
        "venue": "Geology and Resources",
        "year": 2007
    },
    "vynSAxSY": {
        "id": "vynSAxSY",
        "title": "Dynamic Experiment Research on Ammonia Nitrogen as the Major Nitrogen Form Polluting Groundwater",
        "abstract": "The paper researched on the control mechanism of environmental hydro-geochemical feature of Hunhe River basin for nitrogen forms in groundwater.And this offers scientific theory-guidance to groundwater remediation and water source development.By means of dynamic lab-experiment,we simulate the migrating and transforming course of ammonia nitrogen in polluted river permeating in soil column.The experimental soil column was filled with representative sand of Quaternary period loose sediment which are taken from a 100m deep drilling section near the Hunhe River bank.And through intermittentlg.monitoring the differences between time and the indexes of water sample such as ammonia nitrogen,nitrate,nitrite,iron ions,manganese ions,chloride ion,CODMn as well as PH value,we analyse the transformation mechanism among different sorts of nitrogen and the influence of other environmental factors on nitrogen transformation.The result shows that in reducing environment of PH<7 and high concentration of iron ions and manganese ions in groundwater,the major nitrogen form polluting groundwater is ammonia nitrogen.Using statistic method to analye the change tendency of each index,ammonia nitrogen appears positive correlation with manganese ions and CODMn,and negative correlation with nitrate.The conclusion is that regional environmental hydro-geochemical field exists,and water saturated rock stratum characters and structure decide the direction for nitrogen transformation.",
        "keywords": [
            "ammonia nitrogen",
            "groundwater",
            "nitrogen transformation",
            "iron and manganese"
        ],
        "authors": [
            {
                "name": "YANG Wei",
                "org": "School of Municipal and Environmental Engineering,Shenyang Jianzhu University,Shenyang ,China"
            },
            {
                "name": "GUO Yu",
                "org": "School of Municipal and Environmental Engineering,Shenyang Jianzhu University,Shenyang ,China"
            },
            {
                "name": "WANG Yong",
                "org": "School of Municipal and Environmental Engineering,Shenyang Jianzhu University,Shenyang ,China"
            },
            {
                "name": "YANG Junfeng",
                "org": "School of Municipal and Environmental Engineering,Shenyang Jianzhu University,Shenyang ,China"
            },
            {
                "name": "WANG Lidong",
                "org": "School of Municipal and Environmental Engineering,Shenyang Jianzhu University,Shenyang ,China"
            },
            {
                "name": "WANG Hu",
                "org": "School of Municipal and Environmental Engineering,Shenyang Jianzhu University,Shenyang ,China"
            }
        ],
        "venue": "Journal of Shenyang Jianzhu University(Natural Science)",
        "year": 2007
    },
    "N8AWYwp6": {
        "id": "N8AWYwp6",
        "title": "Research on preparation of anion-cation organic bentonite and affecting factors of Cr(Ⅵ) absorption",
        "abstract": "In this paper,Liaoning Heishan bentonite was made into anion-cation organic bentonite through different processes by adding CTMAB and SDS.the Cr(Ⅵ) absorption mechanism of anion-cation organic bentonite was discussed,and the effect of every experiment factor on Cr(Ⅵ) absorption was analyzed by the orthogonal test,which supplied one kind of new reaction medium and technical parameter of the anion-cation organic bentonite used in the new PRB technique of polluted groundwater remediation.The studying result is indicated: Cr(Ⅵ) absorption of anion-cation organic bentonite(Na-R-ACOMMT)is the co-action of physical absorption and chemical absorption;pH and adding amount are the most important factors for the absorption effect,especially pH;the optimal conditions for Na-RACOMMT adsorbing Cr(Ⅵ) are sample amount of 10g/L,60～80,40℃,pH of 2 and oscillating for 60 min with a frequency of 150 r/min.Under this condition,the absorption rate is high to 93.55%,and the absorption isotherm accords with Langmuir and Freundlich equation.",
        "keywords": [
            "absorption isotherm",
            "permeable reactive barrier",
            "anion-cation organic bentonite",
            "orthogonal test"
        ],
        "authors": [
            {
                "name": "YANG Wei",
                "org": "Municipal and Environmental Engineering College of Shenyang Architecture University,Shenyang ,China"
            },
            {
                "name": "YANG Jun-feng",
                "org": "Municipal and Environmental Engineering College of Shenyang Architecture University,Shenyang ,China"
            },
            {
                "name": "WANG Li-dong",
                "org": "Municipal and Environmental Engineering College of Shenyang Architecture University,Shenyang ,China"
            },
            {
                "name": "JIA Ming",
                "org": "Shenyang Civil Building Engineering Corporation,Shenyang ,China"
            },
            {
                "name": "GUO Yu",
                "org": "Municipal and Environmental Engineering College of Shenyang Architecture University,Shenyang ,China"
            },
            {
                "name": "WANG Hu",
                "org": "Municipal and Environmental Engineering College of Shenyang Architecture University,Shenyang ,China"
            }
        ],
        "venue": "Hydrogeology & Engineering Geology",
        "year": 2007
    },
    "o6ldMXMB": {
        "id": "o6ldMXMB",
        "title": "Research and application of on-line monitoring management system for urban sewage treatment",
        "abstract": "The on-line monitoring management system was designed urban sewage treatment,which included the on-line instrument monitor system,data delivering system and the information management system.The advanced technology was applied by the city sewage treatment online monitoring system,such as the examination of water quality,the wireless correspondence,the network,the GIS and so on.The provincial level sewage treatment system has realized network,the automation,the intellectualization,which provides the scientific supervising and managing method for the sewage treatment industry.",
        "keywords": [
            "management system",
            "sewage treatment",
            "on-line monitor"
        ],
        "authors": [
            {
                "name": "WANG Guang-hui",
                "org": "Shenyang Jianzhu University,Shenyang ,China"
            },
            {
                "name": "YANG Wei",
                "org": "Shenyang Jianzhu University,Shenyang ,China"
            },
            {
                "name": "WANG Hu",
                "org": "Shenyang Jianzhu University,Shenyang ,China"
            }
        ],
        "venue": "Energy Conservation",
        "year": 2007
    },
    "SK1ndPqw": {
        "id": "SK1ndPqw",
        "title": "Research into the comparison of two groundwater vulnerable models",
        "abstract": "By comparing and analyzing linear weighting DRASTIC and the AHP in which the fuzzy mathematics is applied, the more suitable ground water vulnerable model is opted for assessing the groundwater vulnerability in certain cities of central and southern Liaoning Province. According to the data from previous exploration and material collection, the DRASTIC and AHP models are applied to assess the groundwater vulnerability. A better model is adopted by comparing the process and the result of the two assessing models. The results of the two assessment methods show similar tendency. However, AHP is more practical and its final result is more easily understood and adopted by policy-makers.",
        "keywords": [
            "AHP",
            "DRASTIC",
            "Fuzzy assessment",
            "Groundwater vulnerability assessment"
        ],
        "authors": [
            {
                "name": "Wei Yang",
                "org": "Shenyang Jianzhu University(Shenyang Jianzhu University ^),Shenyang,China"
            },
            {
                "name": "Hu Wang",
                "org": "Shenyang Jianzhu University(Shenyang Jianzhu University ^),Shenyang,China"
            },
            {
                "name": "Baolan Li",
                "org": "Investigation Institute of Hydrogeology and Engineering Geology of Liaoning Province(),Dalian,China"
            },
            {
                "name": "Lidong Wang",
                "org": "Shenyang Jianzhu University(Shenyang Jianzhu University ^),Shenyang,China"
            },
            {
                "name": "Yu Guo",
                "org": "Shenyang Jianzhu University(Shenyang Jianzhu University ^),Shenyang,China"
            },
            {
                "name": "Junfeng Yang",
                "org": "Shenyang Jianzhu University(Shenyang Jianzhu University ^),Shenyang,China"
            }
        ],
        "venue": "Shenyang Jianzhu Daxue Xuebao (Ziran Kexue Ban)/Journal of Shenyang Jianzhu University (Natural Science)",
        "year": 2007
    },
    "i47LYuKJ": {
        "id": "i47LYuKJ",
        "title": "Study on Manufacture of the Novel Modified Bentonite and Its Adsorption Properties of Cr(Ⅵ)",
        "abstract": "The preparation condition for the integrated modified bentonite(MB) as Cr(Ⅵ) adsorbent was studied.The influence factors and mechanism of adsorbing Cr(Ⅵ) were discussed,with aiming at researching and developing a kind of harmless and economic reaction medium of Permeate Reactive Barrier in-situ remediation technology.A new modifying method on Ca-bentonite of Liaoning Heishan by carbon-entraining has been presented with the modifier of Al2(SO4)3 by roasting.The best modified condition is that the modifier Al2(SO4)3 of 25g and carbon of 2g are added in bentonite of 100g,respectively,and roasting temperature of 420 ℃ and roasting time of 2 h selected.Using MB to treat the water polluted by Cr(Ⅵ),the removal rate of 98.21% are achieved with Cr(Ⅵ) concentration of 1 mg/L,the temperature of 13.5 ℃,pH value of 6.5,MB dosage of 20 g/L and reaction time of 45 min.The Cr(Ⅵ) concentration of treated water is less than the national groundwater quality Ⅲ standard.Simultaneously,the MB shows the advantage of no-desorption and easier liquid-solid separation.It is feasible with MB as the reaction medium of PRB to remedy the polluted soil and groundwater by the Cr(Ⅵ).",
        "keywords": [
            "modifier",
            "roasting",
            "carbon-entraining",
            "aluminum-sulfate",
            "remediation"
        ],
        "authors": [
            {
                "name": "YANG Wei",
                "org": "School of Municipal and Environmental Engineering,Shenyang Jianzhu Uiversity,Shengyang China,"
            },
            {
                "name": "WANG Lidong",
                "org": "School of Municipal and Environmental Engineering,Shenyang Jianzhu Uiversity,Shengyang China,"
            },
            {
                "name": "LIN Sen",
                "org": "School of Municipal and Environmental Engineering,Shenyang Jianzhu Uiversity,Shengyang China,"
            },
            {
                "name": "YANG Junfeng",
                "org": "School of Municipal and Environmental Engineering,Shenyang Jianzhu Uiversity,Shengyang China,"
            },
            {
                "name": "WANG Hu",
                "org": "School of Municipal and Environmental Engineering,Shenyang Jianzhu Uiversity,Shengyang China,"
            }
        ],
        "venue": "Journal of Shenyang Jianzhu University(Natural Science)",
        "year": 2007
    },
    "uscQxYuF": {
        "id": "uscQxYuF",
        "title": "Preparation of anion-cation organic bentonite and its adsorption of phenol",
        "abstract": "Many anion-cation organic bentonite samples were prepared by reaction of raw bentonite (Heishan, Liaoning) with hexadecyl trimethyl ammonium bromide (CTMAB) and/or lauryl sodium sulfate (SDS) for study of the effects of baking temperatures and chemical composition on the organic content and the phenol removal capacity of the product. The most desirable modified bentonite was prepared by reaction with 120CTMAB/15SDS and 3.0% Na2CO3. The synergistic effect of ion exchange and adsorption in removing organic substance was demonstrated. Series of batch adsorption runs were conducted to determine the effects of temperature, adsorbent dose, particle size, pH, contact time, and agitation intensity on the modified bentonite’s capacity for phenol. 78.74% phenol removal was achieved by treatment of 1 mg/L phenol solution by 60 g/L of the modified bentonite under the conditions: particle size = 80-100 mesh, temperature = 20 ℃, pH = 6-8, agitation speed = 200 r/min and contact time = 30 min. The observed adsorption isotherm data were well represented by either Langmuir or Freundlich model. Heating the dry spent adsorbent at 105 ℃ for 1 h recovered a large portion of its original phenol capacity; the regenerated Na-ACOMMT was reusable up to 6 adsorption-regeneration cycles for a cumulative capacity of 0.045 9 mg/g. About 2.73% of CTMAB and 16.06% of SDS were released from the modified bentonite in the adsorption runs. The chemical release should be reduced for cost effective use of the modified bentonite in groundwater remediation.",
        "keywords": [
            "Anion-cation organic bentoniteModified bentonitePhenolRegenerationDesorption"
        ],
        "authors": [
            {
                "name": "Yang Wei",
                "org": "School of Municipal and Environmental Engineering, Shenyang Jianzhu University, Shenyang Liaoning "
            },
            {
                "name": "Yang Junfeng",
                "org": "School of Municipal and Environmental Engineering, Shenyang Jianzhu University, Shenyang Liaoning "
            },
            {
                "name": "Wang Lidong",
                "org": "School of Municipal and Environmental Engineering, Shenyang Jianzhu University, Shenyang Liaoning "
            },
            {
                "name": "Jia Ming",
                "org": "Shenyang Civil Construction Engineering Corporation, Shenyang Liaoning "
            },
            {
                "name": "Guo Yu",
                "org": "School of Municipal and Environmental Engineering, Shenyang Jianzhu University, Shenyang Liaoning "
            },
            {
                "name": "Wang Hu",
                "org": "School of Municipal and Environmental Engineering, Shenyang Jianzhu University, Shenyang Liaoning "
            }
        ],
        "venue": "Environmental Pollution & Control",
        "year": 2007
    },
    "LStpuH3F": {
        "id": "LStpuH3F",
        "title": "Advanced Treatment of Coking Wastewater with Inorganic/Organic Composite Modified Bentonite",
        "abstract": "Through the organic and inorganic composite modification of the calcium-base bentonite from Heishan of Liaoning Province,an efficient and inexpensive adsorbent was developed and used in advanced treatment of coking wastewater. The influences of factors such as bentonite size,reaction temperature,adsorbent dosage,pH value,reaction time and so on were investigated. The results show that the bentonite modified with Al2(SO4)3 of 5 g/L and CTMAB of 0.02 mol/L can remove the ammonia nitrogen and COD from the secondary effluent. Under the conditions of the dosage of 40 g/L,time of 30 min,temperature of 25 ℃ and pH value of 9,the removal rates of ammonia nitrogen and COD can reach 75% and 47% respectively. The effluent concentrations of ammonia nitrogen and COD can be reduced to less than 25 mg/L and 150 mg/L respectively. The developed adsorbent creates favorable condition for reclamation and reuse of coking wastewater.",
        "keywords": [
            "ammonia nitrogen",
            "composite modified bentonite",
            "COD",
            "advanced treatment",
            "coking wastewater"
        ],
        "authors": [
            {
                "name": "GUO Hai-xia",
                "org": "School of Municipal and Environmental Engineering,Shenyang Jianzhu University,Shenyang ,China"
            },
            {
                "name": "YANG Wei",
                "org": "School of Municipal and Environmental Engineering,Shenyang Jianzhu University,Shenyang ,China"
            },
            {
                "name": "ZHANG Hong-bo",
                "org": "School of Municipal and Environmental Engineering,Shenyang Jianzhu University,Shenyang ,China"
            }
        ],
        "venue": "China Water & Wastewater",
        "year": 2008
    },
    "ZtIcbfCJ": {
        "id": "ZtIcbfCJ",
        "title": "Research on the Influences of Regional Geochemical Indexes on Nitrogen Transformation in Aeration Zone",
        "abstract": "This paper analyses the influences of hydro-geochemical features at Shenyang Hun River Basin on the transformation of ammonia nitrogen of groundwater aeration zone,which provides theoretic directions for evaluating and forecasting groundwater pollution.It also studies the process and mechanism of nitrogen transformation and the influences of hydro-geochemical factors based on the in-site samples and laboratory experiments,including the experiment of simulating process of ammonia nitrogen polluting ground aeration zone.The results show that nitrate nitrogen is the main form of nitrogen pollution in aeration zone and regional environmental hydro-geochemical feature and nitrogen transformation influences each other.",
        "keywords": [
            "groundwater ammonia nitrogen nitrate nitrogen aeration zone"
        ],
        "authors": [
            {
                "name": "GUO Yu",
                "org": "1.School of Municipal and Environmental Engineering,Shenyang Jianzhu University Shenyang "
            },
            {
                "name": "YANG Wei",
                "org": "1.School of Municipal and Environmental Engineering,Shenyang Jianzhu University Shenyang "
            },
            {
                "name": "HONG Yan",
                "org": ""
            }
        ],
        "venue": "Industrial Safety and Environmental Protection",
        "year": 2008
    },
    "v23hS16b": {
        "id": "v23hS16b",
        "title": "Remediation of Cd/Cu Contaminated Soil Using Composite Leaching Agent",
        "abstract": "A leaching technology was applied to treat the contaminated soil by Cd and Cu in Shenyang Zhangshi Irrigation Area using a composites solution which makes up of V(0.1mol/LCA)∶V(0.3mol/L sodium citrate) = 1∶1.Batch experiments were performed to test the influence of composites solution pH,liquid-solid ratio,and time.Results show that utilization of composites solution was effective for removal of Cd and Cu from the contaminated soil,attaining 90.25% of Cd,62.85% of Cu at pH is 6,liquid-solid ratio is 25/1within 24 h.Such a remediation procedure indicates that composites solution is a promising agent for remediation of Cd and Cu contaminated soils.",
        "keywords": [
            "Heavy metal",
            "Leaching agent",
            "Remediation",
            "Soil pollution"
        ],
        "authors": [
            {
                "name": "YANG Wei",
                "org": "School of Municipal and Environmental Engineering,Shenyang Jianzhu University,Shenyang China,"
            },
            {
                "name": "ZHANG Hongbo",
                "org": "School of Municipal and Environmental Engineering,Shenyang Jianzhu University,Shenyang China,"
            },
            {
                "name": "GUO Haixia",
                "org": "School of Municipal and Environmental Engineering,Shenyang Jianzhu University,Shenyang China,"
            },
            {
                "name": "YANG Peiming",
                "org": "Shenyang Water Project Bidding Co.,Ltd.,Shenyang China,"
            }
        ],
        "venue": "Journal of Shenyang Jianzhu University(Natural Science)",
        "year": 2008
    },
    "GFVOZnEt": {
        "id": "GFVOZnEt",
        "title": "Study on Nitrogen Migration and Transformation in the Zone of Aeration and the Zone of Saturation by Sand Column Experiments",
        "abstract": "The regional features of nitrogen pollutant form in rock and soil at Shenyang section of the Hunhe River Basin were discussed.In two sand column experiments,different transformation processes of ammonia nitrogen were observed by taking different polluting sources,ways and media into account in the zone of aeration and the zone of saturation,respectively.According to the regional hydrogeochemical environmental characteristics,ammonia nitrogen,nitrate,nitrite,total iron,manganese ions,COD_(Mn),pH,E_h and(ρ(DO)) were selected as the monitoring indexes in the dynamic lab-experiment.The result shows that nitrate nitrogen is the main form of nitrogen pollutant in the aeration zone of columnⅠwith aerobic condition,and ammonia nitrogen is the main form of nitrogen pollutant in the zone of saturation of columnⅡwith anoxic condition.The conclusion is that regional environmental hydrogeochemical field and the characteristics of saturated rock strata decide the main form of nitrogen pollutant.",
        "keywords": [
            "ammonia nitrogen",
            "groundwater",
            "zone of saturation",
            "nitrate nitrogen",
            "zone of aeration"
        ],
        "authors": [
            {
                "name": "YANG Wei",
                "org": ""
            },
            {
                "name": "GUO Yu",
                "org": ""
            },
            {
                "name": "WANG Xiao-hua",
                "org": ""
            },
            {
                "name": "WANG Feng",
                "org": ""
            },
            {
                "name": "YAN Guang-yu",
                "org": "Liaoning Urban Construction Renovation Programs Office,Shenyang ,China"
            }
        ],
        "venue": "Research of Environmental Sciences",
        "year": 2008
    },
    "onCsLyLR": {
        "id": "onCsLyLR",
        "title": "Experiment on Selection of PRB Media and Remediation of Chromium Contaminated Groundwater",
        "abstract": "The selection of the economical and feasible reactive media was studied on in-situ remediation of Cr(Ⅵ) contaminated groundwater in Permeable Reactive Barrier technology through experiment.Four kinds of matrials,viz.the modified bentonite(MB),Fe0,the fly ash and the activated carbon were selected for PRB media testing.The effective and economical modified bentonite was carried on the dynamic experiment as the PRB media.The experimental results indicate that the Cr(Ⅵ) concentration decreases from 0.50 mg/L to 0.05 mg/L which is less than the national groundwater quality Ⅲ standard.Simultaneously,the MB shows the large adsorption quantity,easier liquid-solid separation,no desorption and secondary pollution.It is feasible that the modified bentonite as the PRB media is to remedy the Cr(Ⅵ) contaminated groundwater.",
        "keywords": [
            "permeable reactive barrier",
            "modified bentonite",
            "selection",
            "remediation"
        ],
        "authors": [
            {
                "name": "YANG Wei",
                "org": "School of Municipal and Environmental Engineering,Shenyang Jianzhu University,Shenyang ,China"
            },
            {
                "name": "WANG Li-dong",
                "org": "School of Municipal and Environmental Engineering,Shenyang Jianzhu University,Shenyang ,China;Shenyang Water Supply Engineering Prospecting Design & Research Institute,Shenyang ,China"
            },
            {
                "name": "XU Li",
                "org": "School of Municipal and Environmental Engineering,Shenyang Jianzhu University,Shenyang ,China"
            },
            {
                "name": "YANG Jun-feng",
                "org": "School of Municipal and Environmental Engineering,Shenyang Jianzhu University,Shenyang ,China"
            }
        ],
        "venue": "Journal of Jilin University(Earth Science Edition)",
        "year": 2008
    },
    "Gen9T4oe": {
        "id": "Gen9T4oe",
        "title": "THE PROGRAMMING OF GROUNDWATER VULNERABILITY ASSESSMENT MODEL",
        "abstract": "It can reduce the workload of groundwater vulnerability assessment,and achieve the Visualization of the results of the evaluation that the groundwater vulnerability assessment model,DRASTIC and AHP,are programmed with Visual Basic.The computing work of evaluation can realize with the computer,through the in-depth study of the evaluation formulae and the evaluation's computing process,using variable replacement evaluation index value and weight,and using the programming language compile the formulae and the computing process.Based on the calculated results,the visualization of the assessment results can be achieved by the geographical information system components MapObject.",
        "keywords": [
            "DRASTIC AHP",
            "VB MapObject",
            "Groundwater"
        ],
        "authors": [
            {
                "name": "WANG Hu",
                "org": "1.School of Municipal and Environmental Engineering,Shenyang Jianzhu University,Shenyang ,China"
            },
            {
                "name": "YANG Wei",
                "org": "1.School of Municipal and Environmental Engineering,Shenyang Jianzhu University,Shenyang ,China"
            },
            {
                "name": "WANG Li-dong",
                "org": "1.School of Municipal and Environmental Engineering,Shenyang Jianzhu University,Shenyang ,China"
            },
            {
                "name": "GUO Yu",
                "org": "1.School of Municipal and Environmental Engineering,Shenyang Jianzhu University,Shenyang ,China"
            },
            {
                "name": "YANG Jun-feng",
                "org": "1.School of Municipal and Environmental Engineering,Shenyang Jianzhu University,Shenyang ,China"
            }
        ],
        "venue": "Energy Environmental Protection",
        "year": 2008
    },
    "D9kJ6nWS": {
        "id": "D9kJ6nWS",
        "title": "Advancement in Research on the Carrying Capacity of Water Environment",
        "abstract": "Research on the carrying capacity of water environment is a useful tool for environment planning and sustainable development of economy at home and abroad.This paper is an attempt to review the definitions of carrying capacity of water environment given by different experts,introduce our own definition,sum up its status quo of research on the indicator system,outline four research methods and analyze their deficiencies.It is concluded that the future research on the carrying capacity of water environment should pay more attention to improving the concept system,enhancing the interdisciplinary intersections,deepening quantitative research,and expanding research fields.",
        "keywords": [
            "water environment",
            "indicator system",
            "carrying capacity"
        ],
        "authors": [
            {
                "name": "YANG Wei",
                "org": "College of Municipal Administration and Environmental Engineering,Shenyang Architectual University,Shenyang ,China"
            },
            {
                "name": "LIU Ping",
                "org": "College of Municipal Administration and Environmental Engineering,Shenyang Architectual University,Shenyang ,China"
            },
            {
                "name": "Guo Hai-xia",
                "org": "College of Municipal Administration and Environmental Engineering,Shenyang Architectual University,Shenyang ,China"
            }
        ],
        "venue": "China Rural Water and Hydropower",
        "year": 2008
    },
    "7FeUsmTk": {
        "id": "7FeUsmTk",
        "title": "The Longitudinal Evaluation of Water Environment Carrying Capacity of Liaoning",
        "abstract": "Water environment carrying capacity is an important part of all kinds of environment capacity in the sustained development of a country or region.So it is the bottleneck of restricting the development of human society,the important factors to decide the economic and social development speed and scale.First determine the evaluation index system according to the actual situation of Liaoning and grey correlation method,second use the improved Analytic Hierarchy Process to determine the weight of indicators in the index system,third calculate the water environment carrying capacity of Liaoning from 1999 to 2006 with model method,then analyze longitudinal trend of the water environment carrying capacity of Liaoning,last propose effective suggestions to improve the state of water environment,and make sustainable use of water resources come true.",
        "keywords": [
            "longitudinal evaluation",
            "Liaoning province",
            "water environment carrying capacity"
        ],
        "authors": [
            {
                "name": "Liu Ping",
                "org": "Institute of Municipal and Environmental Engineering of Shenyang Jianzhu University,Shenyang ,China"
            },
            {
                "name": "Yang Wei",
                "org": "Institute of Municipal and Environmental Engineering of Shenyang Jianzhu University,Shenyang ,China"
            },
            {
                "name": "Sun Haoran",
                "org": "Institute of Municipal and Environmental Engineering of Shenyang Jianzhu University,Shenyang ,China"
            }
        ],
        "venue": "Environmental Science and Management",
        "year": 2008
    },
    "odbIXI7S": {
        "id": "odbIXI7S",
        "title": "Modification of Chitosan and Application of its Derivatives in Water Treatment",
        "abstract": "Modification of chitosan and application of its derivatives in water treatment were studied.Heavy metal ions,chemical oxygen demand,chroma and so on could be removed effectively by chitosan derivatives with no secondary pollution.Compared with the traditional chitosan derivatives,composite chitosan derivatives were more economic and efficient.It is significant to water treatment that better new chitosan ramifications will be synthesized,combined with other techniques and their treating effects for complex water.",
        "keywords": [
            "Water environment",
            "Grafting",
            "Cross-linking",
            "Application",
            "Chitosan",
            "Composite modification"
        ],
        "authors": [
            {
                "name": "CHI He",
                "org": "School of municipal and Environmental Engineering,Shengyang Jianzhu Univercity,Shenyang ,China"
            },
            {
                "name": "YANG Wei",
                "org": "School of municipal and Environmental Engineering,Shengyang Jianzhu Univercity,Shenyang ,China"
            },
            {
                "name": "ZHAO Hai-dong",
                "org": "School of municipal and Environmental Engineering,Shengyang Jianzhu Univercity,Shenyang ,China"
            },
            {
                "name": "WEI Zhi-yu",
                "org": "School of municipal and Environmental Engineering,Shengyang Jianzhu Univercity,Shenyang ,China"
            }
        ],
        "venue": "Liaoning Chemical Industry",
        "year": 2009
    },
    "SqhfTxWR": {
        "id": "SqhfTxWR",
        "title": "The Calculation and Analysis of Water Environment Carrying Capacity of Liaoning",
        "abstract": "In this article,the authors use the improved Analytic Hierarchy Process method to determine the index weight of the evaluation index system and calculate water environment carrying capacity of Liaoning with model method.Then the article compare with the national average standard,analyze the situation of the water environment carrying capacity of Liaoning.Finally,the authors get the result that the water envi-ronment carrying capacity of Liaoning is lower than the national average and the quality and quantity carry-ing capacity is the constraints of the water environment of Liaoning.The authors propose effective sugges-tions to improve the state of water environment and make sustainable use of water resources come true.",
        "keywords": [
            "calculation",
            "Liaoning",
            "improvement measures",
            "water environment carrying capacity"
        ],
        "authors": [
            {
                "name": "YANG Wei",
                "org": "School of Municipal and Environmental Engineering,Shenyang Jianzhu University,Shenyang ,China"
            },
            {
                "name": "LIU Ping",
                "org": "School of Municipal and Environmental Engineering,Shenyang Jianzhu University,Shenyang ,China"
            },
            {
                "name": "GUO Haixia",
                "org": "School of Municipal and Environmental Engineering,Shenyang Jianzhu University,Shenyang ,China"
            }
        ],
        "venue": "Journal of Shenyang Jianzhu University(Social Science)",
        "year": 2009
    },
    "ewh8LRyu": {
        "id": "ewh8LRyu",
        "title": "Sensitivity Evaluation of Eco-geological Environment Based on GIS-BP Neural Network-Taking Qianshan Scenic Zone and Its Periphery for Instance",
        "abstract": "After taking 3S technology-based eco-geological environment investigation in Qianshan scenic zone and its periphery for six months,we select eleven sensitive factors,which include vadose lithology,slope,geological disasters,humidity index,vegetation index,soil layer thickness,soil quality,water table depth,runoff coefficient,mining,tourism and so on,to evaluate the sensitivity of the study region by using BP network model on MAPGIS platform.The result not only truly reflect the present in the studied region,but also reveal the characteristics and advantages of BP neural network model based on GIS platform in evaluating the sensitivity of the eco-geological environment.",
        "keywords": [
            "BP neural network model",
            "Sensitivity of eco-geological environment",
            "index system",
            "3S technology"
        ],
        "authors": [
            {
                "name": "SUN Hao-ran",
                "org": "School of Municipal and Environmental,Shenyang Jianzhu University.,Shenyang ,Liaoning,China"
            },
            {
                "name": "YANG Wei",
                "org": "School of Municipal and Environmental,Shenyang Jianzhu University.,Shenyang ,Liaoning,China"
            },
            {
                "name": "GUO Ya-wei",
                "org": "School of Municipal and Environmental,Shenyang Jianzhu University.,Shenyang ,Liaoning,China"
            },
            {
                "name": "LI Ren-feng",
                "org": "Geological Prospecting Institute of Liaoning Metallur-geological Prospecting Bureau,Anshan ,Liaoning,China"
            },
            {
                "name": "GAO Ya-ling",
                "org": "School of Municipal and Environmental,Shenyang Jianzhu University.,Shenyang ,Liaoning,China"
            }
        ],
        "venue": "Ground Water",
        "year": 2009
    },
    "IgNRnfhf": {
        "id": "IgNRnfhf",
        "title": "The Environment Influence of Iron-ore Mining",
        "abstract": "The environment problems which are caused by iron-ore mining have been drawing more attention day by day.The characteristics of iron-ore resource in China both have advantage and disadvantage at the same time,the mining actuality is out of optimism.The whole mining which includes mining,ore-dressing,ore-discharge and tailing discharge have brought lots of environment influence to zone beside the corporations.Finally,some valuable measures were brought forward in this paper.",
        "keywords": [
            "Environment influence",
            "Mining actuality",
            "Measure",
            "Iron ore"
        ],
        "authors": [
            {
                "name": "GAO Ya-ling",
                "org": ""
            },
            {
                "name": "YANG Wei",
                "org": ""
            },
            {
                "name": "WANG Shuo",
                "org": ""
            }
        ],
        "venue": "Liaoning Chemical Industry",
        "year": 2009
    },
    "dphjL9if": {
        "id": "dphjL9if",
        "title": "The eco-geological environment quality assessment about Qianshan scenic zone and its periphery based on 3S technology",
        "abstract": "After taking eco-geological environment investigation of Qianshan scenic zone and its periphery with 3S technology for as long as six months,we have found eco-geological environment problems in the study area and analyzed its effect.By selecting 13 factors including faults,slope,geological disasters,vegetation index,biomass,humidity index,surface water quality,groundwater quality,water resources,dust,land use,mining,tourism and so on,we acquire the result of eco-geological environment quality assessment about Qianshan scenic zone and its periphery in the GIS platform by using AHP fuzzy comprehensive evaluation model,which truly reflect existing eco-geological environment situations of the study area.",
        "keywords": [
            "AHP fuzzy comprehensive evaluation",
            "index system",
            "3S technology",
            "eco-geological environment quality"
        ],
        "authors": [
            {
                "name": "Yang Wei",
                "org": "School of Municipal and Environmental,Shenyang Jianzhu University,Shneyang ,China"
            },
            {
                "name": "Sun Haoran",
                "org": "School of Municipal and Environmental,Shenyang Jianzhu University,Shneyang ,China"
            },
            {
                "name": "Kang Zhiyong",
                "org": "Geological Prospecting Institute of Liaoning Metallur-geological Prospecting Bureau,Anshan ,China"
            },
            {
                "name": "Guo Yawei",
                "org": "School of Municipal and Environmental,Shenyang Jianzhu University,Shneyang ,China"
            },
            {
                "name": "Li Renfeng",
                "org": "Geological Prospecting Institute of Liaoning Metallur-geological Prospecting Bureau,Anshan ,China"
            }
        ],
        "venue": "Geotechnical Investigation & Surveying",
        "year": 2009
    },
    "5UTIGzGV": {
        "id": "5UTIGzGV",
        "title": "Studies on PRB Repairing Multi-Component and One Component of the Polluted Groundwater",
        "abstract": "The purpose of this article is to provide the new way and feasible technical parameters for the development and utilization of Bentonite resources and the Permeable Reactive Barrier(PRB)engineering practice.The object of the study is the polluted groundwater by the multi-component of trash percolating liquid or one-component of phenol.The reaction medium is the Anion-cation organic bentonite in-situ remediation study on the polluted groundwater.The experiment results show that the cationic-anionic surfactants have entered into interlayer structure of bentonite and increased the interlayer distance from 0.949 nm of the purified bentonite to 1.988 nm of the Anion-cation organic bentonite.The synergistic effect of ion exchange and adsorption in removing organic substance has been demonstrated.The adsorption of Cr6+ is the mutual effect result of physical adsorption and chemical absorption.The adsorption of ammonium is the ion adsorption and exchange.In the experiment stable stage,the removal rates of COD and Cr6+ of the multi-component,ammonium and phenol of the one-component are 50%,40% and 50% respectively.It is feasible that Anion-cation organic bentonite as the reaction medium of PRB is used to remedy the polluted groundwater.At the same time,the effect of remediation of the polluted groundwater by one-component is better than that by the multi-components.",
        "keywords": [
            "Anion-cation organic bentonite",
            "ion adsorption",
            "PRB",
            "in-situ remediation"
        ],
        "authors": [
            {
                "name": "YANG Wei",
                "org": "School of Municipal and Environmental Engineering,Shenyang Jianzhu University,Shenyang China,"
            },
            {
                "name": "YANG Junfeng",
                "org": "School of Municipal and Environmental Engineering,Shenyang Jianzhu University,Shenyang China,;Water Supply Engineering Prospecting Design and Research Institute of Shenyang,Shenyang China,"
            },
            {
                "name": "WANG Lidong",
                "org": "School of Municipal and Environmental Engineering,Shenyang Jianzhu University,Shenyang China,;Water Supply Engineering Prospecting Design and Research Institute of Shenyang,Shenyang China,"
            }
        ],
        "venue": "Journal of Shenyang Jianzhu University(Natural Science)",
        "year": 2009
    },
    "xMqcgVoX": {
        "id": "xMqcgVoX",
        "title": "Research on Manufacture of the Fe-Pillaring Bentonite and Its Absorption Properties of Cr(Ⅵ)",
        "abstract": "The preparation method and its preparation factors of the modified bentonite were studied.Fe-pillared bentonite was used as the Absorbent for Cr(Ⅵ)to explore the Absorption factors of the Fe-pillaring Bentonite on the Cr(Ⅵ),with the aim of researching and developing a kind of harmless and economic reaction medium of Permeate Reactive Barrier in-situ remediation technology.On the basis of sodium bentonite,Pillared agent was used to modify the soil.The optimum conditions were determined through orthogonal experiment:Pillared agent:n(OH-)/n(Fe3+)=1∶1.5;the chemical reaction and aging temperature in the preparation of pillared soil:80 ℃;aging time:24 h.The single-factor test was used to study the efficiency of Absorption on a variety of factors and the conclusions indicate that when Fe-pillared bentonite dosage is 4 g/L,pH value is 6 and reaction time is 45 min,the removal rate can achieve 92.3% with Cr(Ⅵ)concentration of 30 mg/L.The Cr(Ⅵ)concentration of treated water is less than the national groundwater quality Ⅲ standard.It is feasible that Fe-pillared bentonite is used as the reaction medium of PRB to remedy the polluted soil and groundwater by the Cr(Ⅵ).",
        "keywords": [
            "bentonite",
            "Pillared agent",
            "Fe-pillared",
            "remediation"
        ],
        "authors": [
            {
                "name": "YANG Wei",
                "org": "School of Municipal and environmental Engineering,Shenyang Jianzhu University,Shengyang China,"
            },
            {
                "name": "LIN Sen",
                "org": "School of Municipal and environmental Engineering,Shenyang Jianzhu University,Shengyang China,"
            },
            {
                "name": "FANG Ran",
                "org": "School of Civil Engineering,Shenyang Jianzhu University,Shengyang China,"
            },
            {
                "name": "FENG Jinli",
                "org": "School of Municipal and environmental Engineering,Shenyang Jianzhu University,Shengyang China,"
            }
        ],
        "venue": "Journal of Shenyang Jianzhu University(Natural Science)",
        "year": 2009
    },
    "qXT15qzl": {
        "id": "qXT15qzl",
        "title": "STUDY ON THE HYDROCHEMICAL CHARACTERISTICS AND EVOLUTION MECHANISM OF GEOTHERMAL FIELD IN NIJIATAI OF ANSHAN CITY",
        "abstract": "Hydrochemistry analysis results has indicated that the geothermal water in Nijia-Tai belongs to the types of HCO3 ·SO4-Na and SO4· HCO3-Na.It also contains a great deal of minerals such as fluoride,strontium and silicon dioxide.By the silicon-enthalpy mixing model,it was deduced that the geothermal water in Nijia-Tai has been mixed with the upper cold groundwater and the mix proportion is between 67% and 83%.The over-exploitation to the geothermal water results in its temperature drop.With the long-term disraption by human-beings,the recharging amount of upper cold aquifer to the lower geothermal water is increasing,which,if not changed,would seriously threat the sustainable utilization of geothermal resources in this area.",
        "keywords": [
            "geothermal field",
            "mixed mode",
            "geothermal-water temperature drop.",
            "mixed with cold groundwater",
            "hydrochemistry"
        ],
        "authors": [
            {
                "name": "YANG Wei",
                "org": " Municipal and Environmental Engineering College of Shenyang Jianzhu University,Shenyang,,China"
            },
            {
                "name": "GUO Ya-wei",
                "org": " Municipal and Environmental Engineering College of Shenyang Jianzhu University,Shenyang,,China"
            },
            {
                "name": "KANG Zhi-yong",
                "org": " Liaoning Geological Exploration Organization Research Institute of Metallurgical Geology Exploration Bureau,Anshan,,China"
            },
            {
                "name": "LI Ren-feng",
                "org": " Liaoning Geological Exploration Organization Research Institute of Metallurgical Geology Exploration Bureau,Anshan,,China"
            },
            {
                "name": "SUN Hao-ran",
                "org": " Municipal and Environmental Engineering College of Shenyang Jianzhu University,Shenyang,,China"
            },
            {
                "name": "CHEN Miao-ju",
                "org": " Municipal and Environmental Engineering College of Shenyang Jianzhu University,Shenyang,,China"
            }
        ],
        "venue": "Environmental Chemistry",
        "year": 2010
    },
    "dAKVgP6h": {
        "id": "dAKVgP6h",
        "title": "Analysis and assessment on the heavy metal pollution in soil of Qianshan scenic adjacent to iron mine",
        "abstract": "The purpose of this article is to grasp the situation of heavy metal pollution in Qianshan scenic soil adjacent to iron mine and to provide data base and scientific basis for the environmental governance of scenic spot and sewage norms of iron mine. Methods of evaluation are potential ecological risk index and Nemerow index which are based on the concentration and toxicity of heavy metals. The results show that the soil around the mining in which heavy metals are all within the standard of regulations belongs to security and slight potential hazard. The soil from ore-discharge and tailings field is both of slightly ecological hazard and on alert level in which Pb is significantly higher. The area between tailings and Wufoding has been polluted moderately and Cd is a serious ecological hazard factor. Moreover, the effective fraction of heavy metals is higher than that of other regions, and vegetation there has highlighted the damage symptoms. Heavy metals generated by iron ore mining have entered into the surrounding environment through various channels, which have made negative effect on soil and vegetation of Qianshan scenic spot.",
        "keywords": [
            "Dual weight",
            "Iron ore",
            "Nemerow index",
            "Potential ecological risk index",
            "Scenic spot",
            "Soil heavy metals pollution"
        ],
        "authors": [
            {
                "name": "Wei Yang",
                "org": "Shenyang Jianzhu University(Shenyang Jianzhu University ^),Shenyang,China"
            },
            {
                "name": "Yaling Gao",
                "org": "Shenyang Jianzhu University(Shenyang Jianzhu University ^),Shenyang,China"
            },
            {
                "name": "Zhiyong Kang",
                "org": "Liaoning Bureau of Metallurgic Geological Exploration(),,China"
            },
            {
                "name": "Renfeng Li",
                "org": "Liaoning Bureau of Metallurgic Geological Exploration(),,China"
            },
            {
                "name": "Shuo Wang",
                "org": "Shenyang Jianzhu University(Shenyang Jianzhu University ^),Shenyang,China"
            }
        ],
        "venue": "Shenyang Jianzhu Daxue Xuebao (Ziran Kexue Ban)/Journal of Shenyang Jianzhu University (Natural Science)",
        "year": 2010
    },
    "gWiILvKx": {
        "id": "gWiILvKx",
        "title": "Simulation of Carrying Capacity of Water Resources in Tieling City Based on System Dynamics Model",
        "abstract": "Taking the complicated system characteristics of large agricultural water demand and serious non-point pollution in Tieling city into consideration,adopting the system dynamics method,the water resources carrying capacity system model for protecting water ecological environment health was established through comprehensive analysis of the system of water resources carrying capacity in Tieling city.Dynamic changes of the carrying capacity of water resources in Tieling city from 2008 to 2020 were simulated under 4 kinds of schemes including current development type,economic development type,anti-pollution and water-saving type and sustainable development type.The results show that the sustainable development type is the most feasible one to raise the carrying capacity of water resources and to ensure harmonious development of society,economy and environment in Tieling city.",
        "keywords": [
            "Water resource carrying capacity",
            "Tieling city",
            "Decision variable",
            "SD model"
        ],
        "authors": [
            {
                "name": "FENG Jin-li",
                "org": "College of Municipal&Environmental Engineering,Shenyang Jianzhu University,Liaoning Shenyang ,China"
            },
            {
                "name": "YANG Wei",
                "org": "College of Municipal&Environmental Engineering,Shenyang Jianzhu University,Liaoning Shenyang ,China"
            },
            {
                "name": "WANG Gui-dong",
                "org": "Jiangmen Institute of Environmental Science,Guangdong Jiangmen ,China"
            },
            {
                "name": "SHI Shuang",
                "org": "College of Municipal&Environmental Engineering,Shenyang Jianzhu University,Liaoning Shenyang ,China"
            },
            {
                "name": "SHEN Ai-lian",
                "org": "College of Municipal&Environmental Engineering,Shenyang Jianzhu University,Liaoning Shenyang ,China"
            }
        ],
        "venue": "Liaoning Chemical Industry",
        "year": 2010
    },
    "O9UkGNbo": {
        "id": "O9UkGNbo",
        "title": "Pa Tience and Enrichment of White Chrysanthemun Agaimst Cadmium",
        "abstract": "Through the study on the sampling test analysis of plant in tailings yard of Dagushan iron mine,screan out White Chrysanthemum as the repair plant.Using pot experiment,study in cadmium pollution soil,the absorption patience and accumulation effect of White Chrysanthemum.Results showed that White Chrysanthemum has strong patience with cadmium pollution,the ground and underground accumulation in soil with the increase of cadmium concentration,on enrichment of cadmium to shoot more than underground.Low concentrations of cadmium on White Chrysanthemum have stimulative effect,biomass gradually decreased when the cadmium concentration was 10~50mg/kg,growth is restrained.Small White Chrysanthemum as a mining native plants has good patience and enrichment against cadmium,further confirmed that White Chrysanthemum as the cadmium pollution repair has potential.",
        "keywords": [
            "White Chrysanthemum",
            "the pot experiment",
            "cadmium contaminated soil",
            "phytoremediation"
        ],
        "authors": [
            {
                "name": "YANG Wei",
                "org": "College of Environmenial and Municipal Engineering Shenyang Jianzhu University,Shenyang ,China"
            },
            {
                "name": "SHEN Ai-lian",
                "org": "College of Environmenial and Municipal Engineering Shenyang Jianzhu University,Shenyang ,China"
            },
            {
                "name": "LI Yong",
                "org": "Terrestrial-heat Resources Management Department of Anshan City,Anshan ,China"
            },
            {
                "name": "FENG Jin-li",
                "org": "College of Environmenial and Municipal Engineering Shenyang Jianzhu University,Shenyang ,China"
            }
        ],
        "venue": "Environmental Science & Technology",
        "year": 2010
    },
    "jKuFYPjL": {
        "id": "jKuFYPjL",
        "title": "Removal Effect of PRB with the Load of Biological Media on Groundwater Nitrate",
        "abstract": "In order to explore the impact of organic carbon,pH,temperature,hydraulic residence time(HRT) and other major factors on the removal of target contaminant,the experiment simulated groundwater environment,nitrate was selected as target contaminant and polyvinyl alcohol(PVA) as the body of microbial load. PRB reaction media was made by microbial immobilization technology-embedding method,immobilizing mixed nitrification and denitrification bacteria. The results indicate that the temperature of water is 13～15℃,pH 7.2～7.5,HRT 2.5h,with the load of biological media of the PRB technology,the nitrate removal efficiency of the whole system was up to 90.1%. Using the load of biological media as a wall material,PRB technology for remediation of nitrate contaminated groundwater is feasible.",
        "keywords": [
            "biological nitrogen removal",
            "immobilized bacteria",
            "nitrate"
        ],
        "authors": [
            {
                "name": "YANG Wei",
                "org": "College of Municipal and Environmental Engineering,Shenyang Jianzhu University,Shengyang ,China"
            },
            {
                "name": "SHI Shuang",
                "org": "College of Municipal and Environmental Engineering,Shenyang Jianzhu University,Shengyang ,China"
            },
            {
                "name": "JIN Feng-yao",
                "org": "College of Municipal and Environmental Engineering,Shenyang Jianzhu University,Shengyang ,China"
            },
            {
                "name": "JI Guang-yu",
                "org": "College of Municipal and Environmental Engineering,Shenyang Jianzhu University,Shengyang ,China"
            },
            {
                "name": "FENG Jin-li",
                "org": "College of Municipal and Environmental Engineering,Shenyang Jianzhu University,Shengyang ,China"
            }
        ],
        "venue": "Environmental Science & Technology",
        "year": 2010
    },
    "GrY5kYWg": {
        "id": "GrY5kYWg",
        "title": "Research on manufacture of the OH-Fe-organo pillaring bentonite and its absorption properties to phenol",
        "abstract": "The preparation method of the OH-Fe-organo pillaring bentonite was studied.Making it as the absorbent for phenol to explore the absorption factors and the adsorption mechanism of the OH-Fe-organo pillaring bentonite on the phenol,with aiming at researching and developing a kind of harmless and economic reaction medium of Permeate Reactive Barrier in-situ remediation technology.On the basis of sodium bentonite,using pillared agent and CTMAB to modify the soil.It reveals that using modified pillared bentonite with surfactant can improve the adsorbing capacity greatly.The conclusions indicate: using 30 g/L dosage of OH-Fe-organo pillaring bentonite,at the reaction time of 45 min and pH value of 8,the removal rate can achieved 82.8% with phenol concentration of 10 mg/L.The phenol concentration of treated water is less than the national groundwater quality Ⅲ standard.It is feasible that OH-Fe-organo pillaring bentonite as the reaction medium of PRB is to remedy the polluted soil and groundwater by the phenol.",
        "keywords": [
            "bentonite",
            "pillared agent",
            "OH-Fe-organo pillaring",
            "remediation"
        ],
        "authors": [
            {
                "name": "LIN Sen",
                "org": "School of Municipal and Environmental Engineering,Shenyang Jianzhu Uiversity,Shengyang "
            },
            {
                "name": "YANG Wei",
                "org": "School of Municipal and Environmental Engineering,Shenyang Jianzhu Uiversity,Shengyang "
            },
            {
                "name": "SHI Shuang",
                "org": "School of Municipal and Environmental Engineering,Shenyang Jianzhu Uiversity,Shengyang "
            },
            {
                "name": "CHEN Miaoju",
                "org": "School of Municipal and Environmental Engineering,Shenyang Jianzhu Uiversity,Shengyang "
            },
            {
                "name": "JIN Fengyao",
                "org": "School of Municipal and Environmental Engineering,Shenyang Jianzhu Uiversity,Shengyang "
            }
        ],
        "venue": "Journal of Huazhong Normal University(Natural Sciences)",
        "year": 2010
    },
    "5F7HHjVS": {
        "id": "5F7HHjVS",
        "title": "Study on Removal of Selenium (Ⅳ) in Groundwater by Chitosan-Coated Quartz Sand",
        "abstract": "This paper focuses on a new,environmentally friendly,economical and efficient adsorbent,which was developed to remove selenium(Ⅳ)from groundwater.It was methodologically adopted that chitosan was loaded on the surface of quartz sand to produce chitosan-coated quartz sand.The results on pH,adsorption time,reaction temperature and initial mass concentration of selenium(Ⅳ),which effect the removal rate of selenium(Ⅳ),were investigated by static experiments.They show that under the conditions of pH value of 3,adsorption time of 35 min,reaction temperature of 15 ℃,when the initial mass concentration of selenium(Ⅳ)is 50 μg /L,dosaging 40 g /L,adsorbent can make the mass concentration of selenium(Ⅳ)reduce to 8.66 μg /L,which meets the requirement of Sanitary Standard for Drinking Water(GB5746-2006).The conclusion could be reached that chitosan-coated quartz sand can efficiently remove selenium(Ⅳ)from groundwater.Monolayer adsorption is the primary adsorption mechanism of chitosan-coated quartz sand adsorbing selenium(Ⅳ),which basically consistent with Langmuir and Freundlich isotherm equation,especially the correlation of Langmuir adsorption isotherm curve fitting of test data is relatively better.",
        "keywords": [
            "groundwater",
            "selenium(Ⅳ)",
            "quartz sand",
            "chitosan",
            "adsorption isotherm"
        ],
        "authors": [
            {
                "name": "YANG Wei",
                "org": "School of Municipal and Environmental Engineering,Shengyang Jianzhu University,Shenyang China,"
            },
            {
                "name": "CHI He",
                "org": "School of Municipal and Environmental Engineering,Shengyang Jianzhu University,Shenyang China,"
            },
            {
                "name": "SUN Bingshuang",
                "org": "Liaoning Urban Construction & Renewal Project Office,Shenyang China,"
            },
            {
                "name": "ZHAO Haidong",
                "org": "School of Municipal and Environmental Engineering,Shengyang Jianzhu University,Shenyang China,"
            },
            {
                "name": "WEI Zhiyu",
                "org": "School of Municipal and Environmental Engineering,Shengyang Jianzhu University,Shenyang China,"
            }
        ],
        "venue": "Journal of Shenyang Jianzhu University(Natural Science)",
        "year": 2010
    },
    "uIoLPBKz": {
        "id": "uIoLPBKz",
        "title": "Chemical Forms and Bioavailability of Heavy Metals in Soil of Scenic Adjacent to Iron Ore",
        "abstract": "Three acid co-digestion method and Tessier sequential extraction method were used to analyze contents and specification of heavy metals in soil of Qianshan adjacent to Dagushan Iron Ore,and bioavailability of heavy metals was studied.Experiment results showed that Cd and Cu in the soil had exceeded the allowed upper limit of scenic soil,accounting for 2.45～4.65 times and 1.1～1.95 times of Grade I,Pb and Zn in some individual region had exceeded the standard as well.Cd in soil was dominated in mineral species and carbonate species,with proportion of 58.16%～83.17% and 3.39%～22.91%,Cu existed mainly in mineral species and organic matter species,with proportion of 76.67%～88.82% and 3.75%～20.38%.Pb and Zn exited mainly in mineral species and Fe-Mn oxide species.Heavy metals absorbed by plant included not only exchangeable and carbonate forms,but also iron manganese oxidation state and organic forms which can be released under certain conditions.",
        "keywords": [
            "chemical form",
            "heavy metal",
            "bioavailability",
            "vegetation",
            "iron ore mining"
        ],
        "authors": [
            {
                "name": "YANG Wei",
                "org": "School of Municipal and Environmental Engineering,Architectural University of Shenyang,Shenyang ,China"
            },
            {
                "name": "GAO Ya-ling",
                "org": "School of Municipal and Environmental Engineering,Architectural University of Shenyang,Shenyang ,China"
            },
            {
                "name": "KANG Zhi-yong",
                "org": "Geoogical Survey and Metallurgical Research Institute of Liaoning Province,Anshan ,China"
            },
            {
                "name": "LI Ren-feng",
                "org": "Geoogical Survey and Metallurgical Research Institute of Liaoning Province,Anshan ,China"
            },
            {
                "name": "WANG Shuo",
                "org": "School of Municipal and Environmental Engineering,Architectural University of Shenyang,Shenyang ,China"
            },
            {
                "name": "WU Hui-yuan",
                "org": "China University of Mining,Beijing ,China"
            }
        ],
        "venue": "Environmental Science & Technology",
        "year": 2010
    },
    "2LTyncHR": {
        "id": "2LTyncHR",
        "title": "Epidemiological Analysis on Escherichia Coli of Edema Disease of Swine Using Plasmid DNA Finger Printing",
        "abstract": "Seventeen strains of escherichia coli(E.coli)from organs and tissues of the infected swines in some forms in Guangxi had been isolated and identified by the methods of bacterial morphological observation,cultivation characteristic and bio-chemical reaction.The examination for blood-plate hemolysis and pathogenicity in susceptible swines and chmice indicated that all strains were virulent E.coli.The distribution of sero-types of isolates was scrambling.In the screening test of plasmid DNA from 17 strains of E.coli isolates,the results showed that all strains had one common plasmid profile and the swines were infected by high homology E.coli in genetics,and that isolates(GP_(20-3),GP_(25-1)) and(GP_(18-9),GP_(8-3)) from different infected flocks respectively had same plasmid and the original pathogeny in infected flocks was common.Isolates GP_(18-9) and GP_(8-3) had similar plasmid profiles,but their sero-types were dissimilar.This confirmed that plasmids could be transfered among different sero-type E.coli.",
        "keywords": [
            "finger printing",
            "escherichia coli",
            "plasmid DNA",
            "epidemiology",
            "edema disease",
            "swine"
        ],
        "authors": [
            {
                "name": "PAN Bao-jin",
                "org": "Guangxi Entry-Exit Inspection and Quarantine Bureau,Nanning ,China"
            },
            {
                "name": "XIE Yong-ping",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "YANG Wei",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "SU Dong",
                "org": "Guigang Entry-Exit Inspection and Quarantine Bureau,Guigang ,China"
            }
        ],
        "venue": "China Animal Husbandry & Veterinary Medicine",
        "year": 2006
    },
    "C7TyV9h9": {
        "id": "C7TyV9h9",
        "title": "Cloning and sequence analysis of complete genome and ORF2 gene of porcine circovirus (PCV) type 2",
        "abstract": "Refer to the complete gene sequences of PCV2 published in GenBank,a pair of special primers was designed by reverse PCR method and the complete gene sequence of isolated strain GX-FSH of PCV2 was amplified by PCR.In addition,another pair of primers was used to amplify the complete sequence of ORF2.Then these PCR products were cloned into the pMD 18-T vector,respectively,and the recombined positive plasmids were obtained.The sequences of the cloned PCR products were analyzed and compared to other PCV2 isolations in GenBank,the results indicated that the homology of their nucleotide complete sequence was 94.6%-99.4% and the homology of the related ORF gene was 90.0%-99.1% and that of deduced amino acid was 90.1%-98.7%.Finally,the protein structure of ORF2 was predicted and analyzed by biological software,and it suggested that the secondary structure of mature protein of ORF2 belonged to the β-structure.",
        "keywords": [
            "structure analysis",
            "complete gene",
            "porcine circovirus type 2(PCV2)",
            "ORF2 gene"
        ],
        "authors": [
            {
                "name": "CHEN Ze-xiang",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "ZHENG Lie-feng",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "XIE Yong-ping",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "XU Li-gan",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "YANG Wei",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            }
        ],
        "venue": "Guangxi Agricultural Sciences",
        "year": 2007
    },
    "T4u4XBec": {
        "id": "T4u4XBec",
        "title": "Dynamic change in immunology of duckling after inoculating Riemerella anatipestifer vaccine",
        "abstract": "To investigate the effects of Riemerella anatipestifer(RA) vaccine on the functions of cellular and humoral immunity in duckling,healthy 7-day ducklings were immunized by RA vaccine(5×107CFU/mL).The quantitative changes and proliferation function of T and B lymphocytes in peripheral blood,thymus and bursa of Fabricius spleen of ducklings were determined at 3,7,10,14 and 21 days.The results showed that after immunizing by RA vaccine,the quantities,proliferation function of T and B lymphocytes in peripheral blood and the ANAE+ rate of T lymphocytes in immunity organs of ducklings were higher than that of the control and toxic group,and that of toxic group was lower than that of the control.Our studies revealed the immuno-protective role of RA vaccine against the RA Toxin in duckling.",
        "keywords": [
            "ra vaccine",
            "duckling",
            "b lymphocytes",
            "immunity",
            "t lymphocytes",
            "vaccination",
            "immune response",
            "potency"
        ],
        "authors": [
            {
                "name": "MA Chun-xia",
                "org": " Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "LIANG Jia-sui",
                "org": " College of Animal Science and Technology,Guangxi University,Nanning ,China"
            },
            {
                "name": "CHEN Ze-xiang",
                "org": " Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "YANG Wei",
                "org": " Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "XU Li-gan",
                "org": " Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "XUAN Xiong-biao",
                "org": " Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "HU Shuai",
                "org": " Guangxi Veterinary Research Institute,Nanning ,China"
            }
        ],
        "venue": "Guangxi Agricultural Sciences",
        "year": 2009
    },
    "6o5BSYgI": {
        "id": "6o5BSYgI",
        "title": "A rapid detection method for pathogen of brucellosis",
        "abstract": "Based on the nucleotide sequence encoding OMP-2 gene of Brucella abrtus, a pair of PCR primers were designed and the amplification conditions of PCR were optimized to establish the rapid detection method for the pathogen of brucellosis. The specific detection results showed that 193bp gene fragment could be amplified in template DNA of Brucella abrtus, Brucella melitensis and Brucella suis, the pathogens of brucellosis, by the specific primers, while it could not be amplified in those of Escherichia coli, Staphylococcus aureus and Y. enterocolitica (0∶9). The detection results indicated that the sensitivity of milk samples reached 50 cfu/mL, and that of purified DNA of Brucella reached 1.5pg and the repeatability and stability of them were quite higher. Therefore, PCR detection method for pathogen of brucellosis were found highly specific and sensitive and could be used for rapid diagnosis of brucellosis.",
        "keywords": [
            "omp-2 gene",
            "brucellosis",
            "pathogen detection",
            "pcr",
            "genes",
            "methodology",
            "dna"
        ],
        "authors": [
            {
                "name": "CHEN Ze-xiang",
                "org": "Guangxi Veterinary Research Institute, Nanning , China"
            },
            {
                "name": "XU Li-gan",
                "org": "Guangxi Veterinary Research Institute, Nanning , China"
            },
            {
                "name": "XUAN Xiong-biao",
                "org": "Guangxi Veterinary Research Institute, Nanning , China"
            },
            {
                "name": "YANG Wei",
                "org": "Guangxi Veterinary Research Institute, Nanning , China"
            },
            {
                "name": "HU Shuai",
                "org": "Guangxi Veterinary Research Institute, Nanning , China"
            },
            {
                "name": "XIE Yong-ping",
                "org": "Guangxi Veterinary Research Institute, Nanning , China"
            },
            {
                "name": "PAN Yan",
                "org": "Guangxi Veterinary Research Institute, Nanning , China"
            }
        ],
        "venue": "Guangxi Agricultural Sciences",
        "year": 2009
    },
    "zX5jYSOI": {
        "id": "zX5jYSOI",
        "title": "Detection of Fimbrial Gene of Pathogenic Escherichia coli from Piglets in Guangxi Region by Multiplex PCR Assay and Its Plasmid Profile Analysis",
        "abstract": "The fimbrial gene of fifty-six strains of pathogenic Escherichia coli from piglets in Guangxi were detected by multiplex PCR and analysised by plasmid profile.The results showed that the multiplex PCR assay could be used to detect the wild type E.coli strains and also had been proved to be the useful method for rapid diagnosis and epidemiological investigation of piglets diarrhoea caused by E.coli.Plasmid were discovered in all E.coli strains and the isolates from different sources had distinct plasmid patterns,while those from same sources held same plasmids.All strains contained a plasmid with the same size,which indicated that the pathogenic E.coli caused piglets diarrhoea in Guangxi had one common plasmid. The results of analysis suggested that Plasmid DNA Finger Printing method is useful to subtype the Escherichia coli.",
        "keywords": [
            "Guangxi zhuang Aotonomous Region",
            "plasmid profile analysis",
            "piglets",
            "fimbrial gene",
            "Escherichia coli",
            "multiplex PCR"
        ],
        "authors": [
            {
                "name": "XIE Yong-ping",
                "org": "Guangxi Veterinary Research Institute,Nanning Guangxi "
            },
            {
                "name": "PENG Hao",
                "org": "Guangxi Veterinary Research Institute,Nanning Guangxi "
            },
            {
                "name": "CHEN Ze-xiang",
                "org": "Guangxi Veterinary Research Institute,Nanning Guangxi "
            },
            {
                "name": "YANG Wei",
                "org": "Guangxi Veterinary Research Institute,Nanning Guangxi "
            }
        ],
        "venue": "Modern Agricultural Sciences and Technology",
        "year": 2010
    },
    "w46Y6s3j": {
        "id": "w46Y6s3j",
        "title": "Proteome analysis of Riemerella anatipestifer by 2-DE",
        "abstract": "To establish two dimensional electrophoresis(2-DE) for proteome analysis of Riemerella anatipestifer and obtain high quality and reproducible 2-DE maps.Total cellular proteins were extracted by optimizing lysis buffer.0.8mg protein were loaded onto pH4-7IPG strip for 2-DE followed by staining with Silver nitrate.2-DE image analysis revealed(800±26) protein spots,and pI value was mainly ranged from 4.13 to7.40.The matching spots were(600±20) in two repeated electrophoregrams,with matching rate of 75.2%.2-DE of Riemerella anatipestifer has been successfully established with high quality and resolution,which is valuable for proteomics research of Riemerella anatipestifer.",
        "keywords": [
            "proteomes",
            "Riemerella anatipestifer",
            "two-dimension electrophoresis"
        ],
        "authors": [
            {
                "name": "PAN Yan",
                "org": "Guangxi Veterinary Institute,Nanning ,China"
            },
            {
                "name": "XIE Yu-zhou",
                "org": "Guangxi Veterinary Institute,Nanning ,China"
            },
            {
                "name": "CHEN Ze-xiang",
                "org": "Guangxi Veterinary Institute,Nanning ,China"
            },
            {
                "name": "XIE Yong-ping",
                "org": "Guangxi Veterinary Institute,Nanning ,China"
            },
            {
                "name": "LI Jun",
                "org": "Guangxi Veterinary Institute,Nanning ,China"
            },
            {
                "name": "YANG Wei",
                "org": "Guangxi Veterinary Institute,Nanning ,China"
            },
            {
                "name": "XU Li-gan",
                "org": "Guangxi Veterinary Institute,Nanning ,China"
            }
        ],
        "venue": "Chinese Journal of Veterinary Medicine",
        "year": 2010
    },
    "csGq2VZb": {
        "id": "csGq2VZb",
        "title": "Analysis of comparative proteomics of Riemerella anatipestifer serotype 1 and 2",
        "abstract": "To analyse the total protein expression characteristics of Riemerella anatipestifer(RA) serotype 1 and 2 and the relationship between differentially expressed proteins and serotypes or bacterial virulence,the total proteins from RA serotype 1 and 2 were compared by two-dimension electrophoresis and mass spectrometry.Significant changes in expression of 17 proteins spots were identified by mass spectrometry and the differentially expressed proteins represented eleven types of proteins,including seven outer membrane proteins,five enzymes,three heat shock proteins family,and other two proteins involved in the process of protein synthesis.It was speculated that differentially expressed proteins were closely related to RA serotype and virulence.",
        "keywords": [
            "proteomes",
            "Riemerella anatipestifer",
            "mass spectrometry",
            "two-dimension electrophoresis"
        ],
        "authors": [
            {
                "name": "PAN Yan",
                "org": "Guangxi Veterinary Institute,Nanning ,China"
            },
            {
                "name": "XIE Yu-zhou",
                "org": "Guangxi Veterinary Institute,Nanning ,China"
            },
            {
                "name": "CHEN Ze-xiang",
                "org": "Guangxi Veterinary Institute,Nanning ,China"
            },
            {
                "name": "XIE Yong-ping",
                "org": "Guangxi Veterinary Institute,Nanning ,China"
            },
            {
                "name": "LI Jun",
                "org": "Guangxi Veterinary Institute,Nanning ,China"
            },
            {
                "name": "XU Li-gan",
                "org": "Guangxi Veterinary Institute,Nanning ,China"
            },
            {
                "name": "YANG Wei",
                "org": "Guangxi Veterinary Institute,Nanning ,China"
            },
            {
                "name": "XUAN Xiong-biao",
                "org": "Guangxi Veterinary Institute,Nanning ,China"
            },
            {
                "name": "HU Shuai",
                "org": "Guangxi Veterinary Institute,Nanning ,China"
            }
        ],
        "venue": "Chinese Veterinary Science",
        "year": 2010
    },
    "2W0cVGT7": {
        "id": "2W0cVGT7",
        "title": "Establishment and Application of Real-time Fluorescence qPCR Assay for Quick Detection of Riemerella anatipestifer Infection in Ducks",
        "abstract": "The primers and probe were designed according to Riemerella anatipestifer(RA) outer membrane protein(ompA) gene conserved sequence from the GenBank and a real-time fluorescence qPCR quick detection method of RA was established.The detection limit of the method was 8.0 copies/μL of RA DNA.It had a high specificity,was negative to the duck-origin E.coli,Pasteurella multocida,Salmonella,Proteus,Staphylococcus aureus.Ducklings artifically infected with a RA strain,and throat swabs,cloacal swabs,blood,liver,lung and brain were collected,detected by real-time qPCR and isolated pathogenic bacteria.The results of 1/10 half lethal dose inoculation group showed that RA DNA in liver and brain were detected 8 h after infection,all the samples were positive 16 h after,RA were first isolated from liver 24 h after,RA positive rate was 63.8%(51/80) by real-time qPCR while the RA isolation rate was 28.8%(23/80) only.The results of 10 half lethal dose inoculation group showed that RA DNA in throat swab,heart and liver were detected 1 h after infection,all the samples were positive at 5 h,RA were first isolated from the lungs and brain at 5 h,RA positive rate was 86.3%(69/80) by real-time qPCR while the RA isolation rate is 60%(48/80) only.It was only 30 min for extracting RA DNA from detection tissue by pyrolysis.The detection time of the established real-time qPCR method was only 2 h.The method could be used for rapid diagnosis,epidemiological investigation,quarantine of introduction ducks,import and export inspection and quarantine of live ducks and their products.",
        "keywords": [
            "Riemerella anatipestifer",
            "sensitivity",
            "specificity",
            "real-time qPCR",
            "rapid detection"
        ],
        "authors": [
            {
                "name": "XIE Yong-ping",
                "org": "Guangxi Veterinary Research Institute,Nanning 53001,China"
            },
            {
                "name": "PAN Bao-jin",
                "org": "Technology Centre of Guangxi Entry-Exit Inspection and Quarantine Bureau,Nanning ,China"
            },
            {
                "name": "CHEN Ze-xiang",
                "org": "Guangxi Veterinary Research Institute,Nanning 53001,China"
            },
            {
                "name": "XU Li-gan",
                "org": "Guangxi Veterinary Research Institute,Nanning 53001,China"
            },
            {
                "name": "YANG Wei",
                "org": "Guangxi Veterinary Research Institute,Nanning 53001,China"
            },
            {
                "name": "WEI Mei-liang",
                "org": "Technology Centre of Guangxi Entry-Exit Inspection and Quarantine Bureau,Nanning ,China"
            }
        ],
        "venue": "China Animal Husbandry & Veterinary Medicine",
        "year": 2010
    },
    "4OH7CM6w": {
        "id": "4OH7CM6w",
        "title": "Identification of pigs Escherichia Coli O157 isolates obtained in Guangxi province of china",
        "abstract": "In order to investigate whether or not Escherichia Coli O157 infection in domestic pigs in Guangxi farms,Samples of fresh faeces or faecal swab were collected and cultured by enriching in novobiocin mEC broth ,and transferred to O157 chromogenic medium,those suspicious strains were further identified with specificity antiserum and PCR.finally,The result confirmed five different strains were Escherichia Coli O157:H7 ,Animal study showed that these strains’s death rate for mouse between 33.3% and 100%,the investigation indicted that strong pathogenicity Escherichia Coli O157:H7 strain existed in domestic pigs in Guangxi farms.",
        "keywords": [
            "isolation and identification",
            "toxic experiment",
            "EC O157:H7",
            "PCR"
        ],
        "authors": [
            {
                "name": "Xuan Xiong-biao",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "Chen Ze-xiang",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "Xie Yong-ping",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "Hu Shuai",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "Xu Li-gan",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "Yang Wei",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            }
        ],
        "venue": "Chinese Journal of Animal Health Inspection",
        "year": 2010
    },
    "Z63aP2uo": {
        "id": "Z63aP2uo",
        "title": "Isolation and identification of Riemerella anatipestifer and its resistance to antibiotics",
        "abstract": "In order to investigate the occurrence and prevalent serotype and pathogenic bacterial resistance to antibi-otics of infectious serositis,36 suspected strains of Riemerella anatipestifer were collected from more than 20 disease farms in Guangxi.The investigations of cultural,morphological and physio-biochemical characteristics showed that these strains belonged to Riemerella anatipestifer.The identification of serotype by slide and tube agglutination tests indicated that these Riemerella anatipestifer strains were of 1-type,2-type and 3-type of serotype.The sensitivity test results showed that more than 70.0% Riemerella anatipestifer strains were highly sensitive to Ceftriaxone,V Ancef,cefoxitin,cefradine,furadantin and florfenicol,while all of the strains were resistant to 23 antibiotics and had 100.0% resistance to doxycycline,gentam-icin,kanamycin and amikacin.",
        "keywords": [
            "riemerella anatipestifer",
            "isolation",
            "identification",
            "resistance to antibiotic",
            "multiple drug resistance",
            "serotypes"
        ],
        "authors": [
            {
                "name": "XIE Yong-ping",
                "org": " Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "CHEN Ze-xiang",
                "org": " Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "XU Li-gan",
                "org": " Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "HU Shuai",
                "org": " Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "XU Guang-xia",
                "org": " Hepu Prevention and Control Centre of Animal Disease,Hepu,Guangxi ,China"
            },
            {
                "name": "XUAN Xiong-biao",
                "org": " Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "YANG Wei",
                "org": " Guangxi Veterinary Research Institute,Nanning ,China"
            }
        ],
        "venue": "Guangxi Agricultural Sciences",
        "year": 2010
    },
    "d0Tkvz1m": {
        "id": "d0Tkvz1m",
        "title": "Investigation on serotypes and antibiotic resistance of swine pathogenic E. coli in Guangxi",
        "abstract": "In order to investigate the serotype and antibiotic resistance of E.coli infection in piglets in Guangxi during the recent years,103 strains of E.coli were isolated from rectal swabs,intestinal contents,mesenteric lymphonodi and other samples of piglets from more than 50 pig farms in 10 cities or counties.The results showed that 103 strains belonged to 29 serotypes,out of which O serotype viz.,O138,O21,O101,O18,O9,O85 were predominant.The antibiotic sensitivity test indicated that most E.coli strains were highly sensitive to ceftriaxone,florfenicol,cefoxitin,ancef,and amikacin.More than 60% strains had antibiotic resistance to penicillin,rifampicin,amoxicillin,doxycycline,kanamycin,streptomycin,furazolidone,etc.So the swine pathogenic strain of E.coli in Guangxi had strong and wide antibiotic resistance to different antibiotics.",
        "keywords": [
            "piglets",
            "guangxi",
            "antibiotic resistance",
            "e.coli",
            "serotype",
            "multiple drug resistance",
            "serotypes"
        ],
        "authors": [
            {
                "name": "XIE Yong-ping",
                "org": " Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "YANG Wei",
                "org": " Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "CHEN Ze-xiang",
                "org": " Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "XU Li-gan",
                "org": " Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "XUAN Xiong-biao",
                "org": " Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "HU Shuai",
                "org": " Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "LI Su-lan",
                "org": " Jieshou Fishery,Animal and Veterinary Station of Xing’an County,Xing’an,Guangxi ,China"
            }
        ],
        "venue": "Guangxi Agricultural Sciences",
        "year": 2010
    },
    "jSJuSSey": {
        "id": "jSJuSSey",
        "title": "Monitoring antibodies of classical swine fever during spring season in Long’an County and countermeasures for develop ingimmune system",
        "abstract": "The immunological effects of classical swine fever vaccine have been investigated during the spring season.Serum samples from pigs in Long’an County were collected randomly in April,2009,and the classical swine fever antibody was detected in serum samples by indirect hemagglutination(HA) method.The results differed significantly in antibody levels and immunological responses in pigs from different townships and towns.The risk of classical swine fever still existed in intensive pig farms.The classical swine fever antibody levels distributed in two extremes and the percentage of pigs in which antibody titer was lower than 1∶2 and 1∶256 were 26.8% and 25.1%,respectively.The immune effect of the whole pigs was relatively worse.Further,the reasons for the poor quality of immunization have been analyzed and the countermeasures for improving the antibody levels were discussed to provide the reference for effective prevention and control of the occurrence and epidemics of classical swine fever.",
        "keywords": [
            "classical swine fever",
            "recommendation",
            "immune antibody level",
            "countermeasure",
            "positive indirect hemagglutination(ha)",
            "antibodies",
            "immune system"
        ],
        "authors": [
            {
                "name": "LI Chang-ting",
                "org": " Long’an Center of Animal Disease Prevention and Control,Long’an,Guangxi ,China"
            },
            {
                "name": "NIU Jin-tao",
                "org": " Jiyuan Bureau of Animal Husbandry,Jiyuan,Henan ,China"
            },
            {
                "name": "PENG Qun-ming",
                "org": " Long’an Center of Animal Disease Prevention and Control,Long’an,Guangxi ,China"
            },
            {
                "name": "LI Li",
                "org": " Long’an Center of Animal Disease Prevention and Control,Long’an,Guangxi ,China"
            },
            {
                "name": "YANG Wei",
                "org": " Guangxi Veterinary Research Institute,Nanning ,China"
            }
        ],
        "venue": "Guangxi Agricultural Sciences",
        "year": 2010
    },
    "1girBdjW": {
        "id": "1girBdjW",
        "title": "Study on the Inactivated Oil-adjuvant Trivalent Vaccine Against Riemerella anatipestifer",
        "abstract": "In order to prevent more effectively Riemerella anatipestifer(RA) disease from spreading,the inactivated oil-adjuvant trivalent vaccine against RA infection was developed with RA three different serotypes.These tests were carried out by vaccine immunization doses,safety,immunogenicity and preservative period.The results showed that the vaccine was safe and effective.0.5 mL vaccine was vaccinated in neck of duck subcutaneously and ducks can resist the attack of RA.The immune protection period was 50 days.The vaccine storage period was 6 months at 4 ℃-8 ℃.The RA inactivated oil-adjuvant trivalent vaccine developed in this study was good in safety and immunogenicity.",
        "keywords": [
            "safety",
            "inactivated oil-adjuvant trivalent vaccine",
            "Riemerella anatipestifer",
            "immunogenicity"
        ],
        "authors": [
            {
                "name": "XIE Yong-ping",
                "org": "Guangxi Veterinary Research Institute,Nanning,Guangxi,,China"
            },
            {
                "name": "CHEN Ze-xiang",
                "org": "Guangxi Veterinary Research Institute,Nanning,Guangxi,,China"
            },
            {
                "name": "XU Li-gan",
                "org": "Guangxi Veterinary Research Institute,Nanning,Guangxi,,China"
            },
            {
                "name": "WU Li-jie",
                "org": "Guangxi Veterinary Research Institute,Nanning,Guangxi,,China"
            },
            {
                "name": "YANG Wei",
                "org": "Guangxi Veterinary Research Institute,Nanning,Guangxi,,China"
            },
            {
                "name": "PAN Yan",
                "org": "Guangxi Veterinary Research Institute,Nanning,Guangxi,,China"
            },
            {
                "name": "XUAN Xiong-biao",
                "org": "Guangxi Veterinary Research Institute,Nanning,Guangxi,,China"
            },
            {
                "name": "LI Jun",
                "org": "Guangxi Veterinary Research Institute,Nanning,Guangxi,,China"
            },
            {
                "name": "HU Shuai",
                "org": "Guangxi Veterinary Research Institute,Nanning,Guangxi,,China"
            }
        ],
        "venue": "Progress in Veterinary Medicine",
        "year": 2010
    },
    "sBen5gS2": {
        "id": "sBen5gS2",
        "title": "Immune Efficacy of Classical Swine Fever Virus Vaccine in Porcine Cirovirus-2 Positive Pig Farm",
        "abstract": "To explore the effect on immune efficacy of classical swine fever vaccine on the porcine cirovirus-2(PCV-2) positive pigs that were confirmed by PCR,the antibodies of classical swine fever virus(CSFV) and PCV-2 were detected by ELISA at 1,3,7,14,21,28 and 63 days post inoculation,with classical swine fever vaccine.The results showed that neither CSFV antibody nor CSFV nucleic acid was detected from all of PCV-2 positive pigs.Although PCV-2 antibody was detected from one of PCV-2 positive pigs,the PCV-2 nucleic acid was detected from all of PCV-2 positive pigs.Typical pathological changes of lymph nodes and significantly decreased leucocyte number were also observed from PCV-2 positive pigs.The results indicated that the infection of PCV-2 could impair the immune system of pigs,thus inhibit the effect on immune efficacy of classical swine fever vaccine.",
        "keywords": [
            "effect",
            "immune",
            "Classical swine fever vaccine",
            "Porcine cirovirus-2"
        ],
        "authors": [
            {
                "name": "PAN Yan",
                "org": "Guangxi Veterinary Institute,Nanning,Guangxi,,China"
            },
            {
                "name": "LI Jun",
                "org": "Guangxi Veterinary Institute,Nanning,Guangxi,,China"
            },
            {
                "name": "XUAN Xiong-biao",
                "org": "Guangxi Veterinary Institute,Nanning,Guangxi,,China"
            },
            {
                "name": "CHEN Ze-xiang",
                "org": "Guangxi Veterinary Institute,Nanning,Guangxi,,China"
            },
            {
                "name": "HU Shuai",
                "org": "Guangxi Veterinary Institute,Nanning,Guangxi,,China"
            },
            {
                "name": "YANG Wei",
                "org": "Guangxi Veterinary Institute,Nanning,Guangxi,,China"
            },
            {
                "name": "XIE Yong-ping",
                "org": "Guangxi Veterinary Institute,Nanning,Guangxi,,China"
            },
            {
                "name": "XU Li-gan",
                "org": "Guangxi Veterinary Institute,Nanning,Guangxi,,China"
            },
            {
                "name": "XIE Yu-zhou",
                "org": "Guangxi Veterinary Institute,Nanning,Guangxi,,China"
            }
        ],
        "venue": "Progress in Veterinary Medicine",
        "year": 2010
    },
    "t1NeKmJ8": {
        "id": "t1NeKmJ8",
        "title": "Epidemiologic survey on Escherichia coli O157∶H7 isolated from domestic animals and domestic birds in Guangxi",
        "abstract": "To acquire the epidemiology data of Escherichia coli(E.coli) O157∶H7 in domestic animals and birds,specimens of animal feces were collected from the farms in Guangxi province from 2007 to 2010.Five strains of E.coli O157∶H7 isolated from 2915 specimens by the methods of morphological,cultural and biochemical characters,serological agglutination reaction as well as PCR identification.The isolated rate was 0.17%.The pathogenicity test showed that isolated E.coli O157∶H7 had different lethality to mice.The lethality rates of mice were among 33.4% to 100%.Drug susceptibility indicated that isolated E.coli O157∶H7 were resistance to Amoxycillin,ampicillin,polymyxin B,Roxithromycin,Rifampicin and Lincomycin.Detection of virulence genes of E.coli O157∶H7 confirmed that the E.coli O157∶H7 with different virulence genes had some relationship with their lethality to mice.Our investigation indicated that E.coli O157∶H7 were mainly existed in pig farms,have certain virulence and antibiotic resistance.",
        "keywords": [
            "antibiotic resistance",
            "E.coli O157∶H7",
            "epidemiology"
        ],
        "authors": [
            {
                "name": "LI Jun",
                "org": "Guangxi Key Labratory of Animal Vaccines and New Technology,Nanning 53001,China"
            },
            {
                "name": "XUAN Xiong-biao",
                "org": "Guangxi Key Labratory of Animal Vaccines and New Technology,Nanning 53001,China"
            },
            {
                "name": "XIE Yu-zhou",
                "org": "Guangxi Key Labratory of Animal Vaccines and New Technology,Nanning 53001,China"
            },
            {
                "name": "XIE Yong-ping",
                "org": "Guangxi Key Labratory of Animal Vaccines and New Technology,Nanning 53001,China"
            },
            {
                "name": "PENG Hao",
                "org": "Guangxi Key Labratory of Animal Vaccines and New Technology,Nanning 53001,China"
            },
            {
                "name": "CHEN Ze-xiang",
                "org": "Guangxi Key Labratory of Animal Vaccines and New Technology,Nanning 53001,China"
            },
            {
                "name": "HU Shuai",
                "org": "Guangxi Key Labratory of Animal Vaccines and New Technology,Nanning 53001,China"
            },
            {
                "name": "Ma Chun-Xia",
                "org": "Guangxi Key Labratory of Animal Vaccines and New Technology,Nanning 53001,China"
            },
            {
                "name": "YANG Wei",
                "org": "Guangxi Key Labratory of Animal Vaccines and New Technology,Nanning 53001,China"
            },
            {
                "name": "XU Li-gan",
                "org": "Guangxi Key Labratory of Animal Vaccines and New Technology,Nanning 53001,China"
            },
            {
                "name": "PAN Yan",
                "org": "Guangxi Key Labratory of Animal Vaccines and New Technology,Nanning 53001,China"
            }
        ],
        "venue": "Chinese Journal of Zoonoses",
        "year": 2011
    },
    "hctP0Dmu": {
        "id": "hctP0Dmu",
        "title": "Genotyping of Haemophilus Parasuis Isolates from Guangxi by ERIC-PCR Fingerprinting",
        "abstract": "In order to study the feasibility of ERIC-PCR assay on genotyping of Haemophilus par asuis,22 Haemophilus parasuis isolates from different pig herds in Guangxi were characterised by ERIC-PCR fingerprinting.It was found that the 22 field isolates of H.parasuis presented 12 special fingerprints and all isolates were typable by the method even serologically non-typable isolates.The results suggested that ERIC-PCR fingerprinting is useful for molecular epidemiological survey and the classification of H.parasuis.",
        "keywords": [
            "fingerprint",
            "ERIC-PCR",
            "Haemophilus parasuis",
            "genotype"
        ],
        "authors": [
            {
                "name": "PENG Hao",
                "org": "Guangxi Veterinary Research Institute,Nanning,Guangxi,,China"
            },
            {
                "name": "LI Jun",
                "org": "Guangxi Veterinary Research Institute,Nanning,Guangxi,,China"
            },
            {
                "name": "XIE Yu-zhou",
                "org": "Guangxi Veterinary Research Institute,Nanning,Guangxi,,China"
            },
            {
                "name": "MA Chun-xia",
                "org": "Guangxi Veterinary Research Institute,Nanning,Guangxi,,China"
            },
            {
                "name": "XUAN Xiong-biao",
                "org": "Guangxi Veterinary Research Institute,Nanning,Guangxi,,China"
            },
            {
                "name": "HU Shuai",
                "org": "Guangxi Veterinary Research Institute,Nanning,Guangxi,,China"
            },
            {
                "name": "YANG Wei",
                "org": "Guangxi Veterinary Research Institute,Nanning,Guangxi,,China"
            },
            {
                "name": "XU Li-gan",
                "org": "Guangxi Veterinary Research Institute,Nanning,Guangxi,,China"
            },
            {
                "name": "XIE Yong-ping",
                "org": "Guangxi Veterinary Research Institute,Nanning,Guangxi,,China"
            },
            {
                "name": "CHEN Ze-xiang",
                "org": "Guangxi Veterinary Research Institute,Nanning,Guangxi,,China"
            },
            {
                "name": "PAN Yan",
                "org": "Guangxi Veterinary Research Institute,Nanning,Guangxi,,China"
            }
        ],
        "venue": "Progress in Veterinary Medicine",
        "year": 2011
    },
    "raSJpPkq": {
        "id": "raSJpPkq",
        "title": "Analyzing molecular polymorphism of Escherichia coli isolated from goats by randomly amplified polymorphic DNA",
        "abstract": "Randomly amplified polymorphic DNA(RAPD) was used to study the molecular polymorphism of pathogenic Escherichia coli(E.coli) strains isolated from goat in Guangxi.Four random primers were screened from 8 random primers for showing preferably polymorphic amplification of 10 strains E.coli.Totally 18 RAPD bands were identified,however,there was no common RAPD band among the 10 E.coli strains.Nx 31 strain and Nx32 strains were known to be the same isolate by serological typing, however,RAPD bands of two strains exhibited distinct differences,indicating that RAPD had higher distinguishability than serological typing.",
        "keywords": [
            "goat",
            "Escherichia coli",
            "randomly amplified polymorphic DNA"
        ],
        "authors": [
            {
                "name": "LI Jun",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "PENG Hao",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "TAO Li",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "ZHU Juan-juan",
                "org": "College of Animal Science and Technology,Guangxi University,Nanning ,China"
            },
            {
                "name": "CHEN Ze-xiang",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "WEI Zhi-feng",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "LAN Mei-yi",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "QIN Ruo-fu",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "YANG Wei",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            }
        ],
        "venue": "Chinese Journal of Veterinary Medicine",
        "year": 2011
    },
    "CRLwpwpH": {
        "id": "CRLwpwpH",
        "title": "Establishment of real-time quantitative PCR for detection of Escherichia coli O157∶H7",
        "abstract": "To establish a real-time quantitative PCR for detection of Escherichia coli O157∶H7,the Flic(H7) genes from E.coli O157∶H7 in GenBank were aligned and a pair of specific primers was designed from the conserved sequences.The reactive conditions were optimized to improve the sensitivity and specificity of the assay.The results showed that the sensitivity of this assay was 10 times higher than PCR and the detection limit was 103CFU/mL.This assay had good reproducibility and higher specificity.The coefficients of variations in reproducibility test were less than 2%.Specificity test confirmed that this assay could distinguish E.coli O157∶H7 from the other serotypes of E.coli,Streptococcus suis and Haemophilus parasuis.Using this assay to quantitatively detect the mimical samples,the quantitative result was agreed with that of bacterial plate count.This real-time quantitative PCR assay might be used as a powerful tool for the rapid detection of E.coli O157∶H7.",
        "keywords": [
            "Flic(H7) gene",
            "real-time quantitative PCR",
            "E.coli O157∶H7"
        ],
        "authors": [
            {
                "name": "LI Jun",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "XIE Yu-zhou",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "XUAN Xiong-biao",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "CHEN Ze-xiang",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "YANG Wei",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "MA Chun-Xia",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "HU Shuai",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "PENG Hao",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "XU Li-gan",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "XIE Yong-ping",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "PAN Yan",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            }
        ],
        "venue": "Animal Husbandry & Veterinary Medicine",
        "year": 2011
    },
    "833n3CBO": {
        "id": "833n3CBO",
        "title": "Detection and Genotyping of Haemophilus parasuis aroA Gene with PCR-RFLP",
        "abstract": "The PCR assay and PCR-RFLP were applied to study the function of aroA gene on the detection and genotyping of Haemophilus parasuis.18 strains of Haemophilus parasuis isolated from swine in Guangxi were detected successfully by using the PCR assay with primers targeted to aroA gene,and the sensitive test showed that the lowest amount of Hps detectable by this PCR-based test was 102.The aroA gene of the 18 strains was sequenced,and enzyme restriction analysis of the aroA sequences available was performed to define which restriction enzymes more practical.HindⅢ and FokⅠ were chosen to do RFLP analysis in all 18 Haemophilus parasuis strains and one reference strain.The result of the analysis showed that there were three patterns among the groups.The study suggests that the PCR assay and PCR-RFLP applied to detection and genotyping are useful to further research the biological characteristics and gene function of Haemophilus parasuis.",
        "keywords": [
            "Haemophilus parasuis",
            "PCR-RFLP",
            "pathogen detection"
        ],
        "authors": [
            {
                "name": "PENG Hao",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "XIE Yu-zhou",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "LI Jun",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "XUAN Xiong-biao",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "MA Chun-xia",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "HU Shuai",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "YANG Wei",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "XU Li-gan",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "XIE Yong-ping",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "CHEN Ze-xiang",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "PAN Yan",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            }
        ],
        "venue": "China Animal Husbandry & Veterinary Medicine",
        "year": 2011
    },
    "JlNPzGiT": {
        "id": "JlNPzGiT",
        "title": "Epidemiological Investigation of Haemophilus parasuis in Guangxi",
        "abstract": "Bacterial isolation was carried out from 86 samples of pigs with suspected multiple serositis and arthritis from 60 pig farms in Nanning,Guilin and Yulin,Guangxi province during May 2009 to November 2010.26 strains of Hemophilus parasuis(H.parasuis) were identified by bacterial morphological and cultural characteristics,biochemical characteristics as well as PCR.Isolation rate was 30.2%.Serological typing,animal challenge and drug sensitive test were performed on the 26 strains of H.parasuis.The results showed that 26 strains of H.parasuis were composed of 5 strains of serotype 4,3 strains of serotype 5,1 strains of serotype 11,13,14,15,respectively,and 12 strains of unknown serotype.Serotype 13,14 and 5 strains of unknown serotype could cause mouse death;however,pathogenicities of other strains were weak.Drug sensitive test indicated that 70% strains of H.parasuis were high sensitive to Enrofloxacin and Florfenicol,but some strains of H.parasuis were resistant to other drugs.Our investigation results provided an epidemiological basis for prevention and control of H.parasuis infection in Guangxi.",
        "keywords": [
            "epidemiological investigation",
            "Haemophilus parasuis",
            "Guangxi province"
        ],
        "authors": [
            {
                "name": "XUAN Xiong-biao",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "XIE Yu-zhou",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "LI Jun",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "PENG Hao",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "CHEN Ze-xiang",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "HU Shuai",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "XIE Yong-ping",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "MA Chun-xia",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "XU Li-gan",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "YANG Wei",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "PAN Yan",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            }
        ],
        "venue": "China Animal Husbandry & Veterinary Medicine",
        "year": 2011
    },
    "NbBJj3Ae": {
        "id": "NbBJj3Ae",
        "title": "Epidemiological Investigation of Swine Pathogenic E.coli in Guangxi Small and Medium-scale Farms",
        "abstract": "56 strains of swine pathogenic E.coli were isolated from 23 small and medium-scale pig farms in Guangxi,and its serotype identification and detection of drug resistance showed that the 56 strains belonged to 16 serotypes,out of which O serotype viz,O138,O18,O85,O9,O21 were predominant,occupying 69.76%.The detection of drug resistance of 20 frequently used antibiotics indicated that most E.coli trains were highly sensitive to Cephradine,Cefazolin,Ceftriaxone,Cefoxitin,Polymyxin B,Neomycin,Spectinomycin,and Amikacin,but insensitive to Penicillin,Amoxicillin,Doxycycline,Kanamycin,Vancomycin,Lincomycin,which points to the fact that drug resistance of E.coli in these pig farms has been very grave,and that measures such as biotic safety should be strengthened to undertake comprehensive prevention.",
        "keywords": [
            "sensitivity test",
            "Escherichia coli",
            "small and medium-scale farm in Guangxi",
            "serotype"
        ],
        "authors": [
            {
                "name": "CHEN Feng-lian",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "ZHAO Wu",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "HUANG Hong-mei",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "QIN Shao-min",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "HUA Jun",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "MA Ling",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "WU Jian-min",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "YANG Wei",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            }
        ],
        "venue": "China Animal Husbandry & Veterinary Medicine",
        "year": 2011
    },
    "VuQoULdH": {
        "id": "VuQoULdH",
        "title": "Analysis on virulent phenotype in Streptococcus suis type 2, isolated from Guangxi",
        "abstract": "[Objective]The present study was undertaken to investigate the virulent phenotype of the pathogenic Streptococcus suis type 2 (SS2), isolated from sick pigs in Guangxi for providing molecular basis to control SS2 in Guangxi. [Method]PCR method was used to detect 5 virulent genes of SS2 isolates in Guangxi including capsular polysaccharides 2J gene (CPS2J), muramidate released protein gene(MRP), extracellular factor gene (EF), suilysin gene (SLY) and glutamate dehydrogenase gene (GDH). [Result]The results showed that 60% of the phenotypes of SS2 isolates were CPS2J+/MRP+/EF+/SLY+/GDH+, 30% were CPS2J+/MRP+/EF+/SLY-/GDH- and 10% were CPS2J+/MRP+/EF+/SLY-/GDH+. [Conclusion]The results indicated that CPS2J+/MRP+/EF+/SLY+ was one of the dominant virulent phenotype in the pathogenic SS2 isolated from Guangxi, similar to prevent from the SS2 isolates collected from Jiangsu and Sichuan Provinces. The monitoring of SS2 virulent gene should be strengthened to prevent from breaking out the existing SS2 epidemics.",
        "keywords": [
            "genotype analysis",
            "guangxi",
            "streptococcus suis type 2",
            "virulent gene",
            "phenotypes",
            "genes",
            "polymerase chain reaction",
            "epidemiology",
            "disease prevalence",
            "virulence"
        ],
        "authors": [
            {
                "name": "HU Shuai",
                "org": " Guangxi Veterinary Research Institute, Nanning , China"
            },
            {
                "name": "LI Jun",
                "org": " Guangxi Veterinary Research Institute, Nanning , China"
            },
            {
                "name": "ZHU Juan-juan",
                "org": " College of Animal Science and Technology, Guangxi University, Nanning , China"
            },
            {
                "name": "CHEN Ze-xiang",
                "org": " Guangxi Veterinary Research Institute, Nanning , China"
            },
            {
                "name": "XUAN Xiong-biao",
                "org": " Guangxi Veterinary Research Institute, Nanning , China"
            },
            {
                "name": "HE Cai-mei",
                "org": " College of Animal Science and Technology, Guangxi University, Nanning , China"
            },
            {
                "name": "XIE Yong-ping",
                "org": " Guangxi Veterinary Research Institute, Nanning , China"
            },
            {
                "name": "YANG Wei",
                "org": " Guangxi Veterinary Research Institute, Nanning , China"
            },
            {
                "name": "XU Li-gan",
                "org": " Guangxi Veterinary Research Institute, Nanning , China"
            },
            {
                "name": "ZHAO Wu",
                "org": " Guangxi Veterinary Research Institute, Nanning , China"
            },
            {
                "name": "ZENG Yun",
                "org": " College of Animal Science and Technology, Guangxi University, Nanning , China"
            }
        ],
        "venue": "Journal of Southern Agriculture",
        "year": 2011
    },
    "pOgU64HA": {
        "id": "pOgU64HA",
        "title": "Establishment and Application of Real-time Fluorogenetic Quantitative RT-PCR for Detection of Classical Swine Fever Virus",
        "abstract": "To establish a real-time fluorogenetic quantitative RT-PCR assay for detection of classical swine fever virus(CSFV),the 5′ non-translated region sequences of CSFV in GenBank were aligned and a pair of specific primers was designed from the conserved sequence within 5′ non-translated region.The reactive conditions were optimized to improve the sensitivity and specificity of the assay.The results of reproducibility of this assay were reliable and the intra assay variations were not significant.The specificity test proved that this assay had a high specificity which could not detected PRRSV,PRV and PCV2.The assay also proven to be specific,and the detection limit was up to 2×102 copies.The accuracy of real-time fluorogenetic quantitative RT-PCR was evaluated by testing 15 clinical samples.The results of real-time fluorogenetic quantitative RT-PCR were consistent with results of rabbit-cross reaction test,which suggested that real-time quantitative RT-PCR assay may be used as a powerful tool for repaid detection of CSFV.",
        "keywords": [
            "real-time fluorogenetic quantitative RT-PCR",
            "classical swine fever virus"
        ],
        "authors": [
            {
                "name": "LI Jun",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "PAN Yan",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "XUAN Xiong-biao",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "HU Shuai",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "MA Chun-xia",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "XIE Yu-zhou",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "CHEN Ze-xiang",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "XU Li-gan",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "XIE Yong-ping",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "YANG Wei",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            }
        ],
        "venue": "China Animal Husbandry & Veterinary Medicine",
        "year": 2011
    },
    "rUw418jk": {
        "id": "rUw418jk",
        "title": "Isolation and Identification of Pleuropneumonia Pathogen of Black Goat in Guangxi",
        "abstract": "A suspected pleuropneumonia pathogen was isolated from sick black goat from an individual household in Nanning,Guangxi.The results of observation of pathogen growth morphology by optical microscope and electron microscope,as well as biochemical characteristic,growth inhibition test,pathogenicity test of animals and polymerase chain reaction(PCR) showed that this pathogen was Mycoplasma ovipneumonia.",
        "keywords": [
            "black goat",
            "isolation",
            "identification",
            "pleuropneumonia"
        ],
        "authors": [
            {
                "name": "TAO Li",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "LI Jun",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "CHEN Ze-xiang",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "WEI Zhi-feng",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "QIN Ruo-fu",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "YANG Wei",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "LI Zhi-hong",
                "org": "Nanning Animal Health Supervision Institute,Nanning ,China"
            },
            {
                "name": "LAN Mei-yi",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            }
        ],
        "venue": "China Animal Husbandry & Veterinary Medicine",
        "year": 2011
    },
    "KyyvCT41": {
        "id": "KyyvCT41",
        "title": "Establishment of two-dimensional electrophoresis assay for proteome analysis of Escherichia coli O_(157)∶H_7",
        "abstract": "To establish a two-dimensional electrophoresis(2-DE) assay for proteome analysis of Escherichia coli O157∶H7 and to get an electrophoretogram with a clear background,high protein point resolution and good repeatability,2-DE program was optimized,and various sample preparation methods,different loading quantities and different dyeing methods were studied.Samples were ultra sounded with ice bath at 3 minute(9 s/every 9 s) followed by deposited at 4℃ at 24 hours.0.5 mg total protein were loaded onto pH4-7 IPG strip for 2-DE followed by staining with Coomassie Brilliant Blue G-250 nitrate.2-DE image analysis indicated that 850±20 protein spots were recognized,and protein spots were mainly focused between pI values 4.06 to 7.53.Matching rate of repeated electrophoregrams was 95.3%.Ten proteins were randomly chosen to identify by mass spectrum,and detection rate was 100%.Ten proteins were involved in synthesis of Con A,energy metabolism,amino acids metabolism,etc except one protein was hypothetical protein.Establishment of 2-DE assay for Escherichia coli O157∶H7 in this study provide the foundation for Escherichia coli O157∶H7 proteomics research.",
        "keywords": [
            "proteomes",
            "Escherichia coli O157∶H7",
            "two-dimensional electrophoresis"
        ],
        "authors": [
            {
                "name": "XIE Yu-zhou",
                "org": "Guangxi Veterinary Research Institute,Nanning,,China;Guangxi Key Laboratory of Animal Vaccines and New Technology,Nanning,,China"
            },
            {
                "name": "MI Ke",
                "org": "College of life Science and Technology,Guangxi University,Nanning,,China"
            },
            {
                "name": "LI Jun",
                "org": "Guangxi Veterinary Research Institute,Nanning,,China;Guangxi Key Laboratory of Animal Vaccines and New Technology,Nanning,,China"
            },
            {
                "name": "CHEN Ze-xiang",
                "org": "Guangxi Veterinary Research Institute,Nanning,,China;Guangxi Key Laboratory of Animal Vaccines and New Technology,Nanning,,China"
            },
            {
                "name": "PENG Hao",
                "org": "Guangxi Veterinary Research Institute,Nanning,,China;Guangxi Key Laboratory of Animal Vaccines and New Technology,Nanning,,China;College of Animal Science and Technology,Guangxi University,Nanning,,China"
            },
            {
                "name": "MA Chun-Xia",
                "org": "Guangxi Veterinary Research Institute,Nanning,,China;Guangxi Key Laboratory of Animal Vaccines and New Technology,Nanning,,China"
            },
            {
                "name": "XUAN Xiong-biao",
                "org": "Guangxi Veterinary Research Institute,Nanning,,China;Guangxi Key Laboratory of Animal Vaccines and New Technology,Nanning,,China"
            },
            {
                "name": "HU Shuai",
                "org": "Guangxi Veterinary Research Institute,Nanning,,China;Guangxi Key Laboratory of Animal Vaccines and New Technology,Nanning,,China"
            },
            {
                "name": "XU Li-gan",
                "org": "Guangxi Veterinary Research Institute,Nanning,,China;Guangxi Key Laboratory of Animal Vaccines and New Technology,Nanning,,China"
            },
            {
                "name": "XIE Yong-ping",
                "org": "Guangxi Veterinary Research Institute,Nanning,,China;Guangxi Key Laboratory of Animal Vaccines and New Technology,Nanning,,China"
            },
            {
                "name": "YANG Wei",
                "org": "Guangxi Veterinary Research Institute,Nanning,,China;Guangxi Key Laboratory of Animal Vaccines and New Technology,Nanning,,China"
            },
            {
                "name": "BI Bing-fen",
                "org": "Guangxi Veterinary Research Institute,Nanning,,China;Guangxi Key Laboratory of Animal Vaccines and New Technology,Nanning,,China"
            },
            {
                "name": "PAN Yan",
                "org": "Guangxi Veterinary Research Institute,Nanning,,China;Guangxi Key Laboratory of Animal Vaccines and New Technology,Nanning,,China;College of Animal Science and Technology,Guangxi University,Nanning,,China"
            }
        ],
        "venue": "Chinese Journal of Veterinary Medicine",
        "year": 2012
    },
    "MWEWstnG": {
        "id": "MWEWstnG",
        "title": "Investigation of Drug and Disinfectants Resistance of Pig Source E.coli O157∶H7",
        "abstract": "To investigate the information of drug resistance phenotypes and disinfectants resistance of pig source E.coli O157∶H7 isolated from Guangxi,the drug sensitive and disinfectants resistance were assayed.Meanwhile,3 aminoglycoside antibiotic resistance genes,aph(3)-Iia,aadA and aadB were amplified by PCR.The results of drug sensitive to 27 antibiotics showed that 5 strains were sensitive to Florfenicol,Ceftriaxone,Cefoxitin and Cefotaxime.The rate of drug resistance to Roxithromycin,Polymyxin B,Rifampin,Lincomycin,Amoxycilin,Ampicilin and Cephalothin were 100%.The rate of drug resistance to other antibiotics,such as Trobicin,Streptomycin,Cefradine were between 20% and 60%.Among of 5 strains,1 strain,1 strain and 3 strains were resistances to 23,11 and 9 antibiotics,respectively.The results of PCR confirmed that genome of 5 strains contained aminoglycoside antibiotic resistance genes.Antibiotic resistance genes had a certain correlation with drug resistance phenotypes.The results of disinfectants resistance showed that 5 strains were resistance to Povidone lodine solution,Bromogeramine solution,Glutaraldehyde solution,double quaternary ammonium salt-iodine disinfection liquid and compound of peracetic acid,except dischloroisocyanuric acid sodium chloride powder.Our results will provide information to prevention and control of E.coli O157∶H7 in Guangxi.",
        "keywords": [
            "disinfectant resistance",
            "drug resistance",
            "E.coli O157∶H7"
        ],
        "authors": [
            {
                "name": "LI Jun",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "XIE Yu-zhou",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "FENG Shi-wen",
                "org": "College of Animal Science and Technology,Guangxi University,Nanning ,China"
            },
            {
                "name": "PENG Hao",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "CHEN Ze-xiang",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "XUAN Xiong-biao",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "HU Shuai",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "MA Chun-xia",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "XIE Yong-ping",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "YANG Wei",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China"
            },
            {
                "name": "ZENG Yun",
                "org": "College of Animal Science and Technology,Guangxi University,Nanning ,China"
            }
        ],
        "venue": "China Animal Husbandry & Veterinary Medicine",
        "year": 2012
    },
    "Mlbqf9vG": {
        "id": "Mlbqf9vG",
        "title": "Epidemiological investigation of cryptosporidiosis in dairy cattle in Guangxi,China",
        "abstract": "To investigate the prevalence of cryptosporidiosis in dairy cattle in Guangxi Province,Cryptosporidium oocysts were collected by the Sheater's sugar flotation technique and the modified acid-fast stain method from 1 612 fecal samples which were collected from nine Holstein dairy cattle farms and four individual Holstein dairy cattle farms.The Cryptosporidium oocysts were then identified using the PCR-RFLP based on the 18S rRNA gene.Results showed that the infection rate of Cryptosporidium was 11.72%(189/1 612),distributed in seven Holstein dairy cattle farms.The infection rate of Cryptosporidium in 1-6-month-old cattle was 21.3%,which was significantly higher than that in 7-12-month-old cattle(9.6%) and above 1-year-old cattle(3.8%)(P<0.01).The infection rate of Cryptosporidium in winter was higher than that in summer,however,no significant difference was found(P>0.05).PCR-RFLP analysis suggested that seven Cryptosporidium isolates all belonged to Cryptosporidium andersoni.The results indicated that the C.andersoni was the predominant species of Cryptosporidium in dairy cattle in Guangxi.The infection rate of Cryptosporidium in dairy cattle was similar to that in Henan,Jiangsu,Anhui,and Jilin provinces.",
        "keywords": [
            "dairy cattle",
            "Guangxi",
            "Cryptosporidium",
            "epidemiological investigation"
        ],
        "authors": [
            {
                "name": "TAO Li",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China;Guangxi Key Laboratory of Animal Vaccines and New Technology,Nanning ,China"
            },
            {
                "name": "CHEN Ze-xiang",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China;Guangxi Key Laboratory of Animal Vaccines and New Technology,Nanning ,China"
            },
            {
                "name": "WEI Zhi-feng",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China;Guangxi Key Laboratory of Animal Vaccines and New Technology,Nanning ,China"
            },
            {
                "name": "WANG Rong-jun",
                "org": "College of Animal Science and Veterinary Medicine, Henan Agricultural University,Zhengzhou ,China"
            },
            {
                "name": "QIN Ruo-fu",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China;Guangxi Key Laboratory of Animal Vaccines and New Technology,Nanning ,China"
            },
            {
                "name": "LI Jun",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China;Guangxi Key Laboratory of Animal Vaccines and New Technology,Nanning ,China"
            },
            {
                "name": "TANG Lin-sheng",
                "org": "College of Animal Science and Technology, Guangxi University,Nanning ,China"
            },
            {
                "name": "PENG Hao",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China;Guangxi Key Laboratory of Animal Vaccines and New Technology,Nanning ,China"
            },
            {
                "name": "LAN Mei-yi",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China;Guangxi Key Laboratory of Animal Vaccines and New Technology,Nanning ,China"
            },
            {
                "name": "WEI Xiao-rui",
                "org": "College of Animal Science and Technology, Guangxi University,Nanning ,China"
            },
            {
                "name": "YANG Wei",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China;Guangxi Key Laboratory of Animal Vaccines and New Technology,Nanning ,China"
            }
        ],
        "venue": "Chinese Veterinary Science",
        "year": 2012
    },
    "KhvoCsLF": {
        "id": "KhvoCsLF",
        "title": "Development and application of multiplex PCR assay for detection of dairy Cryptosporidium",
        "abstract": "Two pairs of specific primer were designed and synthesized according to the specific sequence of COWP and ITS-1 gene of dairy Cryptosporidium.A multiplex PCR was developed to amplify specific DNA fragment of C.parvum and C.andersoni with the target sequences of 1 033 bp and 263 bp.By optimizing the PCR response condition specific test and the PCR products sequencing,the multi-PCR was established.A total of 1 613 dairy fecal samples isolated from different areas of Guangxi were tested by the multiplex PCR,and then 189 C.andersoni samples and 1 C.parvum sample were detected,which was consistent with conventional Cryptosporidium isolation and identification results.It showed that the established multi-PCR is suitable for the clinical detection and molecular epidemiology survey of dairy Cryptosporidium.",
        "keywords": [
            "Cryptosporidium andersoni",
            "multiplex PCR",
            "Cryptosporidium parvum"
        ],
        "authors": [
            {
                "name": "PENG Hao",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China;Guangxi Key Laboratory of Animal Vaccines and New Technology,Nanning ,China"
            },
            {
                "name": "LI Jun",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China;Guangxi Key Laboratory of Animal Vaccines and New Technology,Nanning ,China"
            },
            {
                "name": "TAO Li",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China;Guangxi Key Laboratory of Animal Vaccines and New Technology,Nanning ,China"
            },
            {
                "name": "CHEN Ze-xiang",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China;Guangxi Key Laboratory of Animal Vaccines and New Technology,Nanning ,China"
            },
            {
                "name": "WEI Zhi-feng",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China;Guangxi Key Laboratory of Animal Vaccines and New Technology,Nanning ,China"
            },
            {
                "name": "XU Li-gan",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China;Guangxi Key Laboratory of Animal Vaccines and New Technology,Nanning ,China"
            },
            {
                "name": "YANG Wei",
                "org": "Guangxi Veterinary Research Institute,Nanning ,China;Guangxi Key Laboratory of Animal Vaccines and New Technology,Nanning ,China"
            }
        ],
        "venue": "Chinese Journal of Zoonoses",
        "year": 2012
    },
    "n12oHcYy": {
        "id": "n12oHcYy",
        "title": "Isolation and Identification of Infectious Bursal Disease Virus NN1107 and Genetic Evolution Analysis",
        "abstract": "In order to analyze molecular character of the infectious bursal disease virus(IBDV) isolate named NN1107,isolated and identified from a chicken flock in Nanning,Guangxi,VP2 hypervariable region(vVP2) of NN1107 was cloned and sequenced after RT-PCR.The sequence analysis showed that the sequence characteristic of NN1107 vVP2 was identical with very virulent IBDV(vvIBDV).The nucleotide sequence compared of NN1107 strain with others vvIBDV strains isolated from Guangxi indicated that there is 96%-99.6% homology among them.Phylogenetic tree of isolate and reference strains based on the nucleotide sequences of vVP2 showed that NN1107 strain was classified as vvIBDV,its evolution relationship was close to BH09 strain,NNTZ(3)strain,NN07122 strain and HP1001 strain isolated in 2004,2005,2007 and 2010,and farther to vaccine strain,such as B87(in),Bursine-2,FW2512.",
        "keywords": [
            "genetic evolution",
            "Infectious bursal disease virus",
            "VP2 hypervariable region",
            "very virulent IBDV"
        ],
        "authors": [
            {
                "name": "LI Jun",
                "org": "Guangxi Veterinary Research Institute,Nanning,Guangxi,53001,China;Guangxi Key Laboratory of Animal Vaccines and New Technology,Nanning,Guangxi,53001,China"
            },
            {
                "name": "TAO Li",
                "org": "Guangxi Veterinary Research Institute,Nanning,Guangxi,53001,China;Guangxi Key Laboratory of Animal Vaccines and New Technology,Nanning,Guangxi,53001,China"
            },
            {
                "name": "LAN Mei-yi",
                "org": "Guangxi Veterinary Research Institute,Nanning,Guangxi,53001,China;Guangxi Key Laboratory of Animal Vaccines and New Technology,Nanning,Guangxi,53001,China"
            },
            {
                "name": "CHEN Ze-xiang",
                "org": "Guangxi Veterinary Research Institute,Nanning,Guangxi,53001,China;Guangxi Key Laboratory of Animal Vaccines and New Technology,Nanning,Guangxi,53001,China"
            },
            {
                "name": "WEI Zhi-feng",
                "org": "Guangxi Veterinary Research Institute,Nanning,Guangxi,53001,China;Guangxi Key Laboratory of Animal Vaccines and New Technology,Nanning,Guangxi,53001,China"
            },
            {
                "name": "PENG Hao",
                "org": "Guangxi Veterinary Research Institute,Nanning,Guangxi,53001,China;Guangxi Key Laboratory of Animal Vaccines and New Technology,Nanning,Guangxi,53001,China"
            },
            {
                "name": "YANG Wei",
                "org": "Guangxi Veterinary Research Institute,Nanning,Guangxi,53001,China;Guangxi Key Laboratory of Animal Vaccines and New Technology,Nanning,Guangxi,53001,China"
            }
        ],
        "venue": "Progress in Veterinary Medicine",
        "year": 2012
    },
    "4E8IssAS": {
        "id": "4E8IssAS",
        "title": "Surveillance analysis of livestock brucellosis in Guangxi Province,China",
        "abstract": "To survey the epidemiology of livestock brucellosis in Guangxi Province,China,16 143 livestock serum samples collected from 14 cities during 2009 to 2011 were detected by rose bengal plate agglutination test and tube agglutination tests.Meanwhile,Brucella isolation and identification were performed from 1 070 livestock spleen,afterbirth and aborted fetus samples,and 10 viscera samples with positive serum.The serology test indicated that 1 boar serum sample in 2009 as well as 1 cattle serum sample and 8 goat serum samples in 2010 were positive,respectively.Comparison of nucleotide sequences of VirB8 gene of B.melitensis isolate with others Brucella showed that VirB8 gene was conservation among Brucella.Our results indicated that livestock quarantine inspection needs to be enhanced for prevention of Brucella's intrusion to Guangxi by livestock introduction.",
        "keywords": [
            "Guangxi",
            "VirB8",
            "surveillance",
            "Brucella"
        ],
        "authors": [
            {
                "name": "LI Jun",
                "org": "Guangxi Veterinary Research Institute,Nanning 53001,China;Guangxi Key Laboratory of Animal Vaccines and New Technology,Nanning 53001,China"
            },
            {
                "name": "CHEN Ze-xiang",
                "org": "Guangxi Veterinary Research Institute,Nanning 53001,China;Guangxi Key Laboratory of Animal Vaccines and New Technology,Nanning 53001,China"
            },
            {
                "name": "YANG Wei",
                "org": "Guangxi Veterinary Research Institute,Nanning 53001,China;Guangxi Key Laboratory of Animal Vaccines and New Technology,Nanning 53001,China"
            },
            {
                "name": "XIE Yong-ping",
                "org": "Guangxi Veterinary Research Institute,Nanning 53001,China;Guangxi Key Laboratory of Animal Vaccines and New Technology,Nanning 53001,China"
            },
            {
                "name": "LI Chang-ting",
                "org": "Animal Disease Prevention and Control Center of Longan,Longan ,China"
            },
            {
                "name": "FU Qi-kuan",
                "org": "Animal Disease Prevention and Control Center of Fangchenggang,Fangchenggang ,China"
            },
            {
                "name": "LUO Yong-quan",
                "org": "Animal Disease Prevention and Control Center of Hezhou,Hezhou ,China"
            },
            {
                "name": "LI Chang-chun",
                "org": "Animal Disease Prevention and Control Center of Jingxi,Jingxi ,China"
            },
            {
                "name": "XU Li-gan",
                "org": "Guangxi Veterinary Research Institute,Nanning 53001,China;Guangxi Key Laboratory of Animal Vaccines and New Technology,Nanning 53001,China"
            },
            {
                "name": "ZHAO Wu",
                "org": "Guangxi Veterinary Research Institute,Nanning 53001,China;Guangxi Key Laboratory of Animal Vaccines and New Technology,Nanning 53001,China"
            }
        ],
        "venue": "Chinese Journal of Zoonoses",
        "year": 2012
    },
    "0WkCj353": {
        "id": "0WkCj353",
        "title": "Differential Proteomic Analysis between Escherichia coli Isolates O157:H7 and O157 from Swine",
        "abstract": "Differential proteomic analysis between E. coli strains O157:H7 and O157 was carried out, in order to clarify the relationship between virulence and differentially expressed proteins of different E. coli strains. Two- dimensional electrophoresis (2-DE) was used to separate bacterial proteins and Image MasterTM 2D Platinum 7.0 software performed variation analysis of the obtained 2D maps. The differentially expressed proteins were identified by mass spectrometry. The 2D maps of bacterial total protein with clear background, high resolution and good reproducibility were obtained. The variation analysis of two samples was performed and a total of 28 differentially expressed protein spots (by fliter Av. ratio>2.0 and ANOVA<0.05) were detected. These protein spots were identified as 23 unique protein groups by mass spectrometry. The functional classification of annotated proteins indicated that seven kinds of proteins were closely related to bacterial virulence including C-lysozyme inhibitor, universal stress protein, LuxS, flagellin and 3 outer membrane proteins. This research provides an important proteomic basis for studying virulence factors, finding pathogenicity differences and establishing the rapid diagnosis kit of the bacterial strain O157:H7.",
        "keywords": [
            "O157:H7",
            "Differential expression",
            "Proteomics",
            "Escherichia coli",
            "O157",
            "Enterohemorrhagic E. coli"
        ],
        "authors": [
            {
                "name": "Xie Yuzhou",
                "org": " Guangxi Veterinary Research Institute, Guangxi Key Laboratory of Animal Vaccines and New Technology, Nanning, "
            },
            {
                "name": "Mi Ke",
                "org": " Guangxi Veterinary Research Institute, Guangxi Key Laboratory of Animal Vaccines and New Technology, Nanning, "
            },
            {
                "name": "Li Jun",
                "org": " Guangxi Veterinary Research Institute, Guangxi Key Laboratory of Animal Vaccines and New Technology, Nanning, "
            },
            {
                "name": "Chen Zexiang",
                "org": " Guangxi Veterinary Research Institute, Guangxi Key Laboratory of Animal Vaccines and New Technology, Nanning, "
            },
            {
                "name": "Xu Ligan",
                "org": " Guangxi Veterinary Research Institute, Guangxi Key Laboratory of Animal Vaccines and New Technology, Nanning, "
            },
            {
                "name": "Yang Wei",
                "org": " Guangxi Veterinary Research Institute, Guangxi Key Laboratory of Animal Vaccines and New Technology, Nanning, "
            },
            {
                "name": "Bi Bingfen",
                "org": " Guangxi Veterinary Research Institute, Guangxi Key Laboratory of Animal Vaccines and New Technology, Nanning, "
            },
            {
                "name": "Xuan Xiongbiao",
                "org": " Guangxi Veterinary Research Institute, Guangxi Key Laboratory of Animal Vaccines and New Technology, Nanning, "
            },
            {
                "name": "Pan Yan",
                "org": " Guangxi Veterinary Research Institute, Guangxi Key Laboratory of Animal Vaccines and New Technology, Nanning, "
            },
            {
                "name": "Hu Shuai",
                "org": " Guangxi Veterinary Research Institute, Guangxi Key Laboratory of Animal Vaccines and New Technology, Nanning, "
            }
        ],
        "venue": "Genomics and Applied Biology",
        "year": 2012
    },
    "Mys75O1R": {
        "id": "Mys75O1R",
        "title": "Establishment of PCR assay for detection of ITS-1 gene in Cryptosporidium andersoni",
        "abstract": "[Objective]The aim of this research was to develop an swiftly efficient PCR detection assay for Cryptosporidium andersoni to provide technical support for investigation of molecular epidemiology. [Method]A pair of specific primer was designed using published ITS-1 gene sequence and a PCR assay system was developed to conduct specificity test, sensitivity test, clinical detection and conventional nest PCR. [Result]The results showed that the specific band was only amplified from C. andersoni using this PCR assay, but not amplified from C. suis, C. bailey , C. parvum, Theileria sergenti, Babesia bovis, Trypanosoma evansi and Oesophagostomum. The BLAST comparative result revealed that these sequences had above 99% homology with the some sequences published in GenBank. The sensitivity of the assay was 5 oocysts per gram in cattle feces. Total 1613 dairy fecal samples were collected from different areas of Guangxi and tested by the newly developed PCR assay and conventional nest PCR, for which the positive detection rate was both recorded as 11.72%. It was proved that the efficiency of these two methods was 100%. [Conclusion]The established PCR assay was suitable for detection of ITS-1 gene in C. andersoni and molecular epidemics investigation because of its rapidness, sensitivity and specificity.",
        "keywords": [
            "Cryptosporidium andersoni",
            "PCR detection",
            "nest PCR",
            "ITS-1 gene"
        ],
        "authors": [
            {
                "name": "PENG Hao",
                "org": "Guangxi Veterinary Research Institute/Guangxi Key Laboratory of Animal Vaccines and New Technology,Nanning , China;College of Animal Science and Technology,Guangxi University,Nanning ,China"
            },
            {
                "name": "LI Jun",
                "org": "Guangxi Veterinary Research Institute/Guangxi Key Laboratory of Animal Vaccines and New Technology,Nanning , China"
            },
            {
                "name": "TAO Li",
                "org": "Guangxi Veterinary Research Institute/Guangxi Key Laboratory of Animal Vaccines and New Technology,Nanning , China"
            },
            {
                "name": "CHEN Ze-xiang",
                "org": "Guangxi Veterinary Research Institute/Guangxi Key Laboratory of Animal Vaccines and New Technology,Nanning , China"
            },
            {
                "name": "TANG Lin-sheng",
                "org": "College of Animal Science and Technology,Guangxi University,Nanning ,China"
            },
            {
                "name": "WEI Xiao-rui",
                "org": "College of Animal Science and Technology,Guangxi University,Nanning ,China"
            },
            {
                "name": "MA Chun-xia",
                "org": "Guangxi Veterinary Research Institute/Guangxi Key Laboratory of Animal Vaccines and New Technology,Nanning , China"
            },
            {
                "name": "XUAN Xiong-biao",
                "org": "Guangxi Veterinary Research Institute/Guangxi Key Laboratory of Animal Vaccines and New Technology,Nanning , China"
            },
            {
                "name": "HU Shuai",
                "org": "Guangxi Veterinary Research Institute/Guangxi Key Laboratory of Animal Vaccines and New Technology,Nanning , China"
            },
            {
                "name": "XU Li-gan",
                "org": "Guangxi Veterinary Research Institute/Guangxi Key Laboratory of Animal Vaccines and New Technology,Nanning , China"
            },
            {
                "name": "XIE Yong-ping",
                "org": "Guangxi Veterinary Research Institute/Guangxi Key Laboratory of Animal Vaccines and New Technology,Nanning , China"
            },
            {
                "name": "YANG Wei",
                "org": "Guangxi Veterinary Research Institute/Guangxi Key Laboratory of Animal Vaccines and New Technology,Nanning , China"
            }
        ],
        "venue": "Journal of Southern Agriculture",
        "year": 2012
    },
    "qUuwLxM4": {
        "id": "qUuwLxM4",
        "title": "Study on the effect of the combination of thalidomide and As_2O_3 on VEGF expression in ANLL",
        "abstract": "Objective To investigate the effect of thalidomide and As_2O_3 to the secretion of VEGF of the cell of ANLL and study if there is coorperation in thalidomide and As_2O_3.Methods From October 2001 to February 2003,23 patients with ANLL were analyzed.Heparinized marrow was taken,then it was putt into Ficoll-isopaque solution to be purified for MNC,which was cultured in the RPMI 1 640 medium,placed in 5% CO_2 saturation and 37℃ to proliferation.Choosing the cells in logarithm growth phase,adding cultural solution to abstaining the cellular density of 2×10~9/L and then putting it into 24-well plates.There are 4 groups :contrast group,thalidomide(300 μg·mL~ -1 )group,As_2O_3(25 μmol/L)group,and thalidomide(300 μg·mL~ -1 )andAs_2O_3(25 μmol/L)group,cultured for 72 hours.Examine the concentration of VEGF in upper liquid with ELISA method.Results The concentration of VEGF in upper liquid of 4 groups were respectively(1 582.67±281.51)ng/L、(1 206.29±264.87)ng/L、(941.72±236.34)ng/L、(639.12±211.98)ng/L.There were statisticd difference(P<0.05).Conclusion (1)Leukemia cell can secrete VEGF.(2)Thalidomide and As_2O_3 can both lower the expression of VEGF in leukemic cells.(3)Thalidomide can enhance the function of anti-leukemia of As_2O_3.",
        "keywords": [
            "Thalidomide",
            "As_2O_3",
            "VEGF"
        ],
        "authors": [
            {
                "name": "Wang Huan",
                "org": ",et al.Department of Hematology,the Second Affiliated Hospital,China Medical University,Shenyang ,China"
            },
            {
                "name": "Li Yingchun",
                "org": ",et al.Department of Hematology,the Second Affiliated Hospital,China Medical University,Shenyang ,China"
            },
            {
                "name": "Yang Wei",
                "org": ",et al.Department of Hematology,the Second Affiliated Hospital,China Medical University,Shenyang ,China"
            }
        ],
        "venue": "Chinese Journal of Practical Internal Medicine",
        "year": 2006
    },
    "uT5RuNWT": {
        "id": "uT5RuNWT",
        "title": "Potential Anti-tumor Function of Cleaved High Molecular Weight Kininogen and Its Molecular Mechanism",
        "abstract": "High molecular weight kininogen (HK) is a multifunctional glycoprotein that highly associated with many pathophysiological processes, such as initiation of the blood coagulation, activation of the complement system and inflammative reaction. Recent studies indicate that cleaved high molecular weight kininogen (HKa) possesses the potential function of anti-tumor. In this review, we summarized the inhibition and active region of HKa in the adhesion of tumor cells and angiogenesis, the inhibition effect in cell migration and proliferation and induce tumor cell apoptosis effect. We also summarized the target which the HKa act on the endothelial cell surface and its molecular mechanism. HKa can inhibite the de novo synthesized of DNA in proliferating cells,decreases cyclin D1 expression, which is a critical component required for the transition from G1 to S phase of the cell cycle, disrupts intracellular signal pathways. Therefore, further study on the signal transduction pathway of HKa is a challenging task.",
        "keywords": [
            "high molecular weight kininogen",
            "cell apoptosis",
            "angiogenesis",
            "cell migration and proliferation",
            "cell adhesion"
        ],
        "authors": [
            {
                "name": "XU Xiu-Yue",
                "org": "Department of Hematology, Second Affiliated Hospital, China Medical University, Shenyang ,China"
            },
            {
                "name": "YANG Wei",
                "org": "Department of Hematology, Second Affiliated Hospital, China Medical University, Shenyang ,China"
            }
        ],
        "venue": "Chinese Journal of Biochemistry and Molecular Biology",
        "year": 2006
    },
    "KuyhU13i": {
        "id": "KuyhU13i",
        "title": "Acute renal failure caused by high-dose methotrexate chemotherapy:two case reports",
        "abstract": "Two patients receiving high-dose methotrexate chemotherapy developed acute renal failure.Patient 1,a 53-year-old woman with non-Hodgkin lymphoma,received high-dose methotrexate chemotherapy.Initially she was infused with methotrexate 500 mg intravenously within half an hour,followed by 3500 mg via infusion pump within 24 hours.Then calcium folinate was given for rescue.The first dose of calcium folinate was 30 mg/m2,followed by 15 mg/m2 intramuscularly once every 6 hours for 8 doses.The patient had no history of chronic renal disease.Her renal function was normal before chemotherapy(SCr 97.1 μmol/L,BUN 4.78 mmol/L).On day 4 after chemotherapy,she developed mild edema of the face and both hands,and oliguria;her SCr increased to 151 μmol/L.Methylprednisolone,furosemide,and calcium carbonate and vitamin D3 were given;her urinary alkalinisation and monitoring of renal function were performed(a peak SCr level of 275 μmol/L).On day 13 after chemotherapy,her renal function returned to within normal range(SCr 96 μmol/L).Patient 2,a 29-year-old man with acute lymphoblastic leukemia,received high-dose methotrexate chemotherapy.Initially he was infused with methotrexate 500 mg intravenously within half an hour,followed by 4500 mg via infusion pump within 24 hours.The regimen of rescue was the same as patient 1.The patient had no history of chronic renal disease.His renal function was normal before chemotherapy(SCr 86.9 μmol/L,BUN 5.35 mmol/L).On day 3 after chemotherapy,he developed generalized edema and oliguria;his SCr increased to 235 μmol/L(peak level 360 μmol/L).The symptomatic treatment was given(the regimen was the same as patient 1).On day 30 after chemotherapy,his renal function returned to within normal range(SCr 89 μmol/L).",
        "keywords": [
            "acute renal failure",
            "adverse reaction",
            "elevated serum creatinine",
            "methotrexate"
        ],
        "authors": [
            {
                "name": "Wang Hongtao",
                "org": "Hematological Center,Shengjing Hospital Affiliated to China Medical University,Shenyang,,Liaoning Province,China"
            },
            {
                "name": "Yang Wei",
                "org": "Hematological Center,Shengjing Hospital Affiliated to China Medical University,Shenyang,,Liaoning Province,China"
            },
            {
                "name": "Sheng Qiuju",
                "org": "Hematological Center,Shengjing Hospital Affiliated to China Medical University,Shenyang,,Liaoning Province,China"
            },
            {
                "name": "Wang Yunxiu",
                "org": "Hematological Center,Shengjing Hospital Affiliated to China Medical University,Shenyang,,Liaoning Province,China"
            },
            {
                "name": "Liu Zhuogang",
                "org": "Hematological Center,Shengjing Hospital Affiliated to China Medical University,Shenyang,,Liaoning Province,China"
            },
            {
                "name": "Li Yingchun",
                "org": "Hematological Center,Shengjing Hospital Affiliated to China Medical University,Shenyang,,Liaoning Province,China"
            },
            {
                "name": "Liao Aijun",
                "org": "Hematological Center,Shengjing Hospital Affiliated to China Medical University,Shenyang,,Liaoning Province,China"
            }
        ],
        "venue": "Adverse Drug Reactions Journal",
        "year": 2008
    },
    "hv3ylLfs": {
        "id": "hv3ylLfs",
        "title": "Effect of Synthetic Peptides Derived from HKa D5 on Proliferation and Apoptosis of MDA-MB-231 Cells",
        "abstract": "Objective To investigate the effect of domain 5 (D5) of cleaved high molecular weight kininogen (HKa) on proliferation and apoptosis of tumor cells,and the function domain for its activity. Methods Recombinant HK domain 5 and synthetic peptides P-5,P-5n,P-5m and P-5c were prepared. The effect of synthetic peptides derived from HKa D5 on proliferation and apoptosis of MDA-MB-231 cells were detected by WST colorimetrical assay and Annexin Ⅴ-FITC/PI double label method. Results Compared with the control group,the cell number decreased significantly with the increase of r-HRD,P-5,P-5n and P-5m,which induced apoptosis in MDA-MB-231 cells,and P-5c did not show inhibitory activity. The morphological changes of MDA-MB-231 cells,such as shrinking and turning round,were observed under the inverted phase contrast microscope after treated with P-5n and P-5m for 24 hours;P-5c did not show inhibitory activity. Conclusion HK r-HRD and peptides derived from HKa D5 can inhibit MDA-MB-231 cell proliferation by inducing apoptosis and the amino acid sequence His-Gly-Lys (HGK) in D5 is the core motif for inhibitory activity.",
        "keywords": [
            "proliferation",
            "MDA-MB-231 cells",
            "apoptosis",
            "cleaved high molecular weight kininogen",
            "amino acid sequence His-Gly-Lys"
        ],
        "authors": [
            {
                "name": "XU Xiu-yue",
                "org": " Department of Hematology,Shengjing Hospital,China Medical University,Shenyang ,China; Department of Hematology,The Liaohe Oil Field Central Hospital,Panjin ,China"
            },
            {
                "name": "YANG Wei",
                "org": " Department of Hematology,Shengjing Hospital,China Medical University,Shenyang ,China"
            },
            {
                "name": "WU Bin",
                "org": " Department of Hematology,Shengjing Hospital,China Medical University,Shenyang ,China"
            },
            {
                "name": "WANG Biao",
                "org": " Department of Hematology,Shengjing Hospital,China Medical University,Shenyang ,China"
            },
            {
                "name": "CHI Zuo-fei",
                "org": " Department of Hematology,Shengjing Hospital,China Medical University,Shenyang ,China"
            },
            {
                "name": "LIU Zhuo-gang",
                "org": " Department of Hematology,Shengjing Hospital,China Medical University,Shenyang ,China"
            }
        ],
        "venue": "Journal of China Medical University",
        "year": 2008
    },
    "k4MNlzSP": {
        "id": "k4MNlzSP",
        "title": "The detection and clinical implications of membranal TF expression on leukemic blasts and plasma F_(1+2) in patients with acute leukemia at presentation",
        "abstract": "Objective To observe the extent of tissue factor(TF)expression on leukemic blasts surface,plasma level of prothrombin fragment 1+2(F1+2)and their correlations in patients with various subtypes of acute leukemia(AL)at first diagnosis,investigating the significance of the parameters for prediction and diagnostic assessment of disseminated intravascular coagulation(DIC)concomitant with AL.Methods Expressional extent of TF was assayed by flow cytometry(FCM)on membrane of mononuclear cells freshly isolated from bone marrow in 50 consecutive AL patients at first diagnosis and 12 \"normal\" controls.Concentration of plasma F1+2 was detected by enzyme-linked immunosorbent assay(ELISA).Results Expressional extent of membranal TF on blasts surface in acute myelogenous leukemia(AML)-M3[(48.23±11.59)%]was higher than that in AML-M1-2,M4 and ALL(P<0.05),having no statistical significance with AML-M5(40.51%).Plasma F1+2 level in AML-M3,M4 and M5 was significantly elevated as compared to normal controls(P<0.05).TF expressional extent and plasma F1+2 level in complicated DIC subgroups were both significantly higher compared with subgroups without DIC(P<0.01).Correlation was shown in the two indicators(r=0.682,P<0.01).Conclusion AL at first diagnosis presents with coagulation activation,manifested by increased TF expression on leukemic blasts membrane and subsequently raised production of thrombin,as is noticed particularly in AML-M3 and M5.TF expressional extent on membrane assayed by FCM may predict and suggest to some extent the potentiality of DIC concomitant with AL.",
        "keywords": [
            "acute leukemia",
            "membrane surface",
            "tissue factor"
        ],
        "authors": [
            {
                "name": "YANG Wei",
                "org": ".Department of Hematology,Shengjing Hospital,China Medical University,Shenyang ,China"
            },
            {
                "name": "WANG Biao",
                "org": ".Department of Hematology,Shengjing Hospital,China Medical University,Shenyang ,China"
            },
            {
                "name": "CHI Zuo-fei",
                "org": ".Department of Hematology,Shengjing Hospital,China Medical University,Shenyang ,China"
            },
            {
                "name": "WU Bin",
                "org": ".Department of Hematology,Shengjing Hospital,China Medical University,Shenyang ,China"
            },
            {
                "name": "LIAO Ai-jun",
                "org": ".Department of Hematology,Shengjing Hospital,China Medical University,Shenyang ,China"
            },
            {
                "name": "LI Ying-chun",
                "org": ".Department of Hematology,Shengjing Hospital,China Medical University,Shenyang ,China"
            },
            {
                "name": "LIU Zhuo-gang",
                "org": ".Department of Hematology,Shengjing Hospital,China Medical University,Shenyang ,China"
            }
        ],
        "venue": "Chinese Journal of Practical Internal Medicine",
        "year": 2008
    },
    "fJH0YTWi": {
        "id": "fJH0YTWi",
        "title": "Complex t(2;8;21)(p12;q22;q22) translocation: a variant t(8;21)in a patient with acute myeloid leukemia(AMLM2)",
        "abstract": "Objective:To investigate the laboratory and clinical characteristics of complex t(2;8;21)(p12;q22;q22) translocation in acute myeloid leukemia. Method:Bone marrow samples were collected to perform morphologic test and flow cytometry analysis; Detecting AML1/ETO chimeric transcript by reverse transcription polymerase chain reaction(RTPCR); Analysing chromosome by a Gbanding method. Result:The patient was diagnosed as acute myeloid leukemia with maturation (AMLM2) with positive AML1/ETO fusion gene and translocation (2;8;21)(p12;q22;q22) by detecting fusion gene and chromosomal karyotype. Conclusion:Variant translocation involved in chromosome region 2p12 may be responsible to the clinical manifestation and prognosis in this case, and more cases are needed for elucidating the clinical and prognostic characteristics.",
        "keywords": [
            "leukemia",
            "translocation",
            "variant"
        ],
        "authors": [
            {
                "name": "WANG Hongtao",
                "org": "Hematological Department of Sheng Jing hospital affiliated to China Medical University, Shen Yang, , China"
            },
            {
                "name": "YANG Wei",
                "org": "Hematological Department of Sheng Jing hospital affiliated to China Medical University, Shen Yang, , China"
            },
            {
                "name": "SHAO Hui",
                "org": "Hematological Laboratory of Sheng Jing hospital affiliated to China Medical University"
            },
            {
                "name": "ZHANG Jihong",
                "org": "Hematological Laboratory of Sheng Jing hospital affiliated to China Medical University"
            },
            {
                "name": "QI Li",
                "org": "Hematological Department of Sheng Jing hospital affiliated to China Medical University, Shen Yang, , China"
            },
            {
                "name": "LIAO Aijun",
                "org": "Hematological Department of Sheng Jing hospital affiliated to China Medical University, Shen Yang, , China"
            },
            {
                "name": "LI Yingchun",
                "org": "Hematological Department of Sheng Jing hospital affiliated to China Medical University, Shen Yang, , China"
            },
            {
                "name": "LIU Zhuogang",
                "org": "Hematological Department of Sheng Jing hospital affiliated to China Medical University, Shen Yang, , China"
            }
        ],
        "venue": "Journal of Clinical Hematology",
        "year": 2009
    },
    "T99W9im8": {
        "id": "T99W9im8",
        "title": "Effectiveness and Safety of Thalidomide for Treating Multiple Myeloma in China:A Meta-analysis",
        "abstract": "Objective To assess the effectiveness and safety of thalidomide for treating multiple myeloma in China.Methods Randomized controlled trials(RCTs)of thalidomide for multiple myeloma were collected from CNKI(1979 to 2008),CBMdisc(1979 to 2008),and VIP(1989 to 2008)databases.Other relevant journals were also handsearched.The methodological quality of the included studies was evaluated,and data analyses were performed using the Cochrane Collaboration's software RevMan 4.3.Results A total of 9 RCTs involving 324 patients were included.As for the total effective rate and complete remission rate,significant differences were found between thalidomide+MP vs.MP alone(RR=1.34,95%CI 1.05 to 1.70;RR=1.77,95%CI 1.26 to 2.49)and thalidomide+VAD vs.VAD alone(RR=1.45,95%CI 1.20 to 1.75;RR=1.73,95%CI 1.25 to 2.39).Conclusion According to the domestic evidence,treatment for multiple myeloma with thalidomide can improve the total effective rate and the complete remission rate.However,more high-quality,large-sample,randomized,double-blind,controlled trials are required.",
        "keywords": [
            "Multiple myeloma",
            "Thalidomide",
            "Meta-analysis",
            "Randomized controlled trial"
        ],
        "authors": [
            {
                "name": "ZHU Ke",
                "org": " Affiliated Shengjing Hospital of Chinese Medical University,Shengyang ,China"
            },
            {
                "name": "LIU Zhuo-gang",
                "org": " Affiliated Shengjing Hospital of Chinese Medical University,Shengyang ,China"
            },
            {
                "name": "YANG Wei",
                "org": " Affiliated Shengjing Hospital of Chinese Medical University,Shengyang ,China"
            },
            {
                "name": "JIANG Ben-chun",
                "org": " Affiliated Shengjing Hospital of Chinese Medical University,Shengyang ,China"
            }
        ],
        "venue": "Chinese Journal of Evidence-Based Medicine",
        "year": 2009
    },
    "xEOOhdz0": {
        "id": "xEOOhdz0",
        "title": "Inducing effect of ursolic acid on apoptosis of K562/DNR",
        "abstract": "Objective By means of vitro cell experiment,the test confirm that ursolic acid have cytotoxicity and inducing apoptosis effect to K562 daunorubicin-resistant lines(K562/DNR).Meawhile,it also tries to find out the best concentration and time on this subject to lay a theoretical foundation of ursolic acid used in the therapy for hematological malignancies.Methods Using WST-8 analysis to do the reaserch on cytotoxicity action situations which ursolic acid react on K562/DNR cells in different concentrations and times.By utilizing fluorescence-activated cell sorter to do the study on inducing apoptosis effects which ursolic acid react on K562/DNR cells in different concentrations and times.Results Ursolic acid possesses obvious inhibition to cell prolifration,so does to inducing apoptosis effect,in a dose-and-time dependent manner.Conclusion Ursolic acid possesses exact antitumor activity to K562/DNR cells.",
        "keywords": [
            "ursolic acid",
            "apoptosis",
            "k562 daunorubicin-resistant(k562/dnr)",
            "cytotoxicity",
            "cell lines",
            "in vitro"
        ],
        "authors": [
            {
                "name": "chi zuofei",
                "org": ""
            },
            {
                "name": "yang wei",
                "org": ""
            },
            {
                "name": "wu bin",
                "org": ""
            },
            {
                "name": "liao aijun",
                "org": ""
            },
            {
                "name": "li yingchun",
                "org": ""
            },
            {
                "name": "zhang rong",
                "org": ""
            },
            {
                "name": "zhang xingang",
                "org": ""
            },
            {
                "name": "wan huihan",
                "org": ""
            },
            {
                "name": "liu zhuogang",
                "org": ""
            }
        ],
        "venue": "Practical Pharmacy and Clinical Remedies",
        "year": 2009
    },
    "ojSWun3B": {
        "id": "ojSWun3B",
        "title": "Systemic lupus erythematosus leading to abnormal blood coagulation:1 case report and review of literature",
        "abstract": "",
        "keywords": [
            "lupus anticoagulant",
            "coagulative function",
            "systemic lupus erythematosus"
        ],
        "authors": [
            {
                "name": "ZHU Ke",
                "org": ".Department of Hematology,Shengjing Hospital Affiliated to China Medical University,Shenyang ,China"
            },
            {
                "name": "YANG Wei",
                "org": ".Department of Hematology,Shengjing Hospital Affiliated to China Medical University,Shenyang ,China"
            },
            {
                "name": "LIU Zhuo-gang",
                "org": ".Department of Hematology,Shengjing Hospital Affiliated to China Medical University,Shenyang ,China"
            }
        ],
        "venue": "Chinese Journal of Practical Internal Medicine",
        "year": 2009
    },
    "7383UGy0": {
        "id": "7383UGy0",
        "title": "Bortezomib combined with dexamethasone for newly diagnosed multiple myeloma",
        "abstract": "OBJECTIVE:To compare the therapeutic effect and adverse events of bortezomib combined with dexamethasone with the traditional chemical therapy to treat previously untreated multiple myeloma (MM). METHODS: A team of bortezomib: patients received bortezomib of 1.0-1.3 mg/m2 by iv push on days 1,4,8, and 11 of a 21 day treatment cycle. Dexamethasone was allowed 20-40 mg/day, iv drop, 1-4 days and 8-11 days,a total of 3-6 treatment cycles were allowed. A team of traditional therapy: The main therapeutic schedules were M2(Carmustine+Cyclophosphamide+Melphalan+Vincristine+Prednisone ) and VAD (Vincristine+Adriamycin+Dexamethasone). RESULTS:The team of bortezomib: 4 patients were CR, 3 patients nCR, 2 patients PR, and 1 patient was MR. The overall response rate (ORR=CR+nCR+PR+MR) was 100%. It was safety to treat in the patients with renal impairment, and probable had the effect with bone remodeling.The main drug-related toxicities were peripheral-neuropathy, herpeszostervirus infection, fatigue and urine retention, but all the adverse responses were relieved or recovered after drug withdrawal. The team of traditional therapy: 2 patients were CR, 2 patients nCR, 10 patients PR, 6 patients MR, and 12 patients NR. ORR was 62.5%. The main drug-related toxicities were nausea, peripheral-neuropathy, infection and thrombocytopenia. The renal injury did not recover after the therapy. Bone pain improved in varying degrees but the bone remodeling was not seen by x-ray. The changes of β2-microglobulin, multiple myeloma cells, lactate dehydrogenase (LDH) and hemoglobin after the different therapies had a statistics difference between the two teams,P<0.05. CONCLUSION: Bortezomib combined with dexamethasone to treat previously untreated multiple myeloma is more effective than the traditional therapy, and the adverse events are light and reversible.",
        "keywords": [
            "combination",
            "multiple myeloma/drug therapy",
            "drug therapy",
            "antineoplastic combined chemotherapy protocols"
        ],
        "authors": [
            {
                "name": "LIAO Ai-jun",
                "org": "Shengjing Hospital of China Medical University, Shenyang ,P.R.China"
            },
            {
                "name": "WANG Xiao-bin",
                "org": "Shengjing Hospital of China Medical University, Shenyang ,P.R.China"
            },
            {
                "name": "WANG Hui-han",
                "org": "Shengjing Hospital of China Medical University, Shenyang ,P.R.China"
            },
            {
                "name": "LIU Zhuo-gang",
                "org": "Shengjing Hospital of China Medical University, Shenyang ,P.R.China"
            },
            {
                "name": "YANG Wei",
                "org": "Shengjing Hospital of China Medical University, Shenyang ,P.R.China"
            },
            {
                "name": "LI Ying-chun",
                "org": "Shengjing Hospital of China Medical University, Shenyang ,P.R.China"
            },
            {
                "name": "ZHANG Rong",
                "org": "Shengjing Hospital of China Medical University, Shenyang ,P.R.China"
            }
        ],
        "venue": "Chinese Journal of Cancer Prevention and Treatment",
        "year": 2009
    },
    "CJpx5i3L": {
        "id": "CJpx5i3L",
        "title": "Research on primary cell culture of neuroblastoma and significance of cell type",
        "abstract": "Objective:The primary cell culture of neuroblastoma(NB) was established to observe the character and cell types in vitro and found the type of NB cells.Methods: Eight cases of NB bone marrow metastases and 4 cases of NB tumors from surgery were used for primary culture.The cell morphology was observed and western blot was performed to detect the specific markers for N,S and I type cells.Soft agar colony-forming was used to detect the malignant power of different cells.The clinical outcome of NB patients was analysed to confirm the directing effects of cell type in NB prognosis.Results:N type cells appeared to be immature neuroblasts and express CgA protein and had moderate colony-forming power.S type cells appeared as large flattened cells and expressed CD44 protein with no colony-forming power.I type cells had morphological features and protein markers of both N and S types,and had highest colony-forming power.In clinical prognosis,N and I cells progressed quickly,with poor outcome and the 3-year-survival was 1/5 and 0(0/4).Othervise,S cells had good clinical outcome with spontaneous or induced regression and the 3-year-survival was 3/3.Conclusion:I type cell had character of stem cell,they expressed the markers of both N and S type cells and had malignant power.The prognosis of N-and I-type cells was poor and S-type cells was good.The three type cells could interconvert or transdifferentiation,suggesting the intricacy of NB.",
        "keywords": [
            "I type",
            "S type",
            "primary culture",
            "neuroblastoma",
            "N type"
        ],
        "authors": [
            {
                "name": "WANG Hong",
                "org": "Pediatric Department,Hematology Center,Shengjing Hospital of China Medical University,Shenyang ,China"
            },
            {
                "name": "YANG Wei",
                "org": "Department of Hematology Disease,Hematology Center,Shengjing Hospital of China Medical University,Shenyang ,China."
            },
            {
                "name": "HAO Liang-chun",
                "org": "Pediatric Department,Hematology Center,Shengjing Hospital of China Medical University,Shenyang ,China"
            }
        ],
        "venue": "Journal of Modern Oncology",
        "year": 2009
    },
    "ho2MdjxI": {
        "id": "ho2MdjxI",
        "title": "Effects of different concentrations of bortezomib on the expression of NF-κB,IκB and P-gp of DNR-resistant K562 cells",
        "abstract": "AIM:To observe the effects of bortezomib(PS-341) on the expression of NF-κB,IκB and P-gp of K562 cells induced by daunorubicin(K562/DNR).METHODS:MTT method was used to determine the drug-resistant K562 cells and the cellular toxicity of bortezomib;Detect the expression of NF-κB,IκB and P-gp of K562/DNR 36 h after receiving the treatment of 100 mg/L DNR only or added with 0.4,4 and 40 μg/L bortezomib.Detect the apoptosis rate in each group respectively and the activity of NF-κB was detected by ELISA method.RESULTS:Compared with the control group,the expressions of NF-κB and P-gp in K562/DNR group could be induced by DNR.When K562/DNR cells were cultured with bortezomib,the expressions of NF-κB and P-gp induced by DNR were significantly suppressed and IκB was increased,these effects increased with the increase of the concentration of PS-341.The results of NF-κB's activity showed that the team of DNR was 25.9±2.5,DNR+0.4 μg/L PS-341 was 20.3±2.0,DNR+4 μg/L PS-341was 6.1±2.5,DNR+40 μg/L PS-341 was 4.6±1.6.The activity of NF-κB was suppressed when PS-341 was added in.The results of apoptosis rate(%) showed that the team of DNR was 22.5±4.6,DNR+0.4 μg/L PS-341 was 31.0±5.2,DNR+4 μg/L PS-341was 43.6±7.7,DNR+40 μg/L PS-341 was 56.0±9.3.The apoptosis rate increased when K562/DNR cells were cultured with bortezomib,these effects increased with the increase of concentration of bortezomib.CONCLUSION:Bortezomib could convert the cellular drug resistance and this effect showed the characteristic of concentration-dependent pattern.",
        "keywords": [
            "NF-kappa B",
            "I-kappa B",
            "P-glycoprotein",
            "K562 cells",
            "proteasome inhibitor"
        ],
        "authors": [
            {
                "name": "LIAO Ai-Jun",
                "org": " Department of Hematology,Shengjing Hospital,China Medical University,Shenyang ,China"
            },
            {
                "name": "YANG Wei",
                "org": " Department of Hematology,Shengjing Hospital,China Medical University,Shenyang ,China"
            },
            {
                "name": "FU Bei-Bei",
                "org": " Department of Hematology,Shengjing Hospital,China Medical University,Shenyang ,China"
            },
            {
                "name": "LI Ying-Chun",
                "org": " Department of Hematology,Shengjing Hospital,China Medical University,Shenyang ,China"
            },
            {
                "name": "ZHANG Rong",
                "org": " Department of Hematology,Shengjing Hospital,China Medical University,Shenyang ,China"
            },
            {
                "name": "LIU Zhuo-Gang",
                "org": " Department of Hematology,Shengjing Hospital,China Medical University,Shenyang ,China"
            }
        ],
        "venue": "Journal of the Fourth Military Medical University",
        "year": 2009
    },
    "MLBEVYfA": {
        "id": "MLBEVYfA",
        "title": "Effect of bortezomib on MAPK signaling pathway of K562/DNR cells]",
        "abstract": "The study was aimed to investigate the effects of bortezomib (BTZ) on the expression of ERK, JNK and P38 in daunorubicin (DNR)-resistant K562 cells (K562/DNR) and to clarify the molecular mechanism of BTZ in reversing the drug-resistance in leukemic cells. The K562/DNR cells and the cellular toxicity of BTZ was determined by MTT, then 4 µg/L of BTZ was chosen to do the experiment. The expression of ERK, JNK, p38 and P-gp of K562/DNR cells treated with DNR only or DNR combined with BTZ for 12, 24 and 36 hours was detected by Western blot. The apoptosis rate in each group was assayed by flow cytometry. The results showed that as compared with DNR group, the expression of P-ERK, P-P38 and P-gp was significantly suppressed (p < 0.05) and the expression of P-JNK was significantly enhanced (p < 0.05) in the cells treated with DNR combined with BTZ. There was no change in the expression of total ERK, P38 and JNK. The effect increased with the prolonging of time. Meanwhile, the apoptosis rate in cells treated with DNR combined with BTZ increased compared with DNR only. It is concluded that the BTZ can reverse the drug resistance in K562/DNR cells by MAPK signaling pathway and increase the apoptosis of leukemic cells. The effect shows the characteristics of time-dependent manner.",
        "keywords": [
            "p38",
            "k562/dnr cell",
            "erk",
            "proteasome inhibitor",
            "jnk"
        ],
        "authors": [
            {
                "name": "Ai-Jun Liao",
                "org": "Department of Hematology,Shengjing Hospital,China Medical University,Shenyang ,Liaoning Province,China"
            },
            {
                "name": "Bei-Bei Fu",
                "org": "Department of Hematology,Shengjing Hospital,China Medical University,Shenyang ,Liaoning Province,China"
            },
            {
                "name": "Hui-Han Wang",
                "org": "Department of Hematology,Shengjing Hospital,China Medical University,Shenyang ,Liaoning Province,China"
            },
            {
                "name": "Ying-Chun Li",
                "org": "Department of Hematology,Shengjing Hospital,China Medical University,Shenyang ,Liaoning Province,China"
            },
            {
                "name": "Kun Yao",
                "org": "Department of Hematology,Shengjing Hospital,China Medical University,Shenyang ,Liaoning Province,China"
            },
            {
                "name": "Rong Zhang",
                "org": "Department of Hematology,Shengjing Hospital,China Medical University,Shenyang ,Liaoning Province,China"
            },
            {
                "name": "Wei Yang",
                "org": "Department of Hematology,Shengjing Hospital,China Medical University,Shenyang ,Liaoning Province,China"
            },
            {
                "name": "Zhuo-Gang Liu",
                "org": "Department of Hematology,Shengjing Hospital,China Medical University,Shenyang ,Liaoning Province,China"
            }
        ],
        "venue": "Zhongguo shi yan xue ye xue za zhi / Zhongguo bing li sheng li xue hui = Journal of experimental hematology / Chinese Association of Pathophysiology",
        "year": 2010
    },
    "z0krOLZM": {
        "id": "z0krOLZM",
        "title": "Autologous stem cell transplantation after high-dose chemotherapy in first-line treatment of follicular lymphoma: A meta-analysis",
        "abstract": "Objective: To assess the effectiveness and safety of autologous stem cell transplantation after high-dose chemotherapy in first-line treatment of follicular lymphoma. Method: Randomized controlled trials (RCTs) of autologous stem cell transplantation after high-dose chemotherapy in first-line treatment of follicular lymphoma were collected from MEDLINE (1990-2009), EMBASE (1990-2009), OVID (1990-2009), and the Cochrane Library (Issue 2, 2009), and the proceedings of ASH were searched manually. The methodological quality of included studies was evaluated, and data analysis was performed with software STATA 10.0 and RevMan 4.3. Result: A total of 4 RCTs involving 941 patients were included. The results of meta-analysis showed that overall survival rate (HR=0.82, 95%CI 0.49 to 1.15), event-free survival rate (HR=0.35, 95%CI 0.24 to 0.47), total remission rate (RR=0.35, 95%CI 0.96 to 1.30), and secondary malignant tumor incidence rate (RR=1.68, 95%CI 0.47 to 6.07). Conclusion: According to the present evidences, autologous stem cell transplantation after high-dose chemotherapy can not improve overall survival rate and total remission rate, but can improve event-free survival rate, and do not increase secondary malignant tumor incidence rate. However, more highquality, multiple-center, large-sample randomized controlled trials are required. © 2010 Editorial Board of Chin J Evid-based Med.",
        "keywords": [
            "Autologous stem cell transplantation",
            "Follicular lymphoma",
            "High-dose chemotherapy",
            "Meta-analysis",
            "Ramdomized controlled trial"
        ],
        "authors": [
            {
                "name": "Ke Zhu",
                "org": "China Medical University Shenyang(China Medical University),Shenyang,China"
            },
            {
                "name": "Ying Yang",
                "org": "China Medical University Shenyang(China Medical University),Shenyang,China"
            },
            {
                "name": "Wei Yang",
                "org": "China Medical University Shenyang(China Medical University),Shenyang,China"
            },
            {
                "name": "Rong Zhang",
                "org": "China Medical University Shenyang(China Medical University),Shenyang,China"
            },
            {
                "name": "Rong Hu",
                "org": "China Medical University Shenyang(China Medical University),Shenyang,China"
            },
            {
                "name": "JIANG Ben-chun",
                "org": "China Medical University Shenyang(China Medical University),Shenyang,China"
            },
            {
                "name": "LIU Zhuo-gang",
                "org": "China Medical University Shenyang(China Medical University),Shenyang,China"
            }
        ],
        "venue": "Chinese Journal of Evidence-Based Medicine",
        "year": 2010
    },
    "bKEhfhOW": {
        "id": "bKEhfhOW",
        "title": "Effect of bortezomib on sensitization of HL-60 cells to TRAIL]",
        "abstract": "This study was aimed to explore whether bortezomib can sensitize HL-60 cells to TNF-related apoptosis-inducing ligand (TRAIL) and to investigate its possible mechanism. The HL-60 cells were treated by different concentrations of TRAIL combined with subtoxic concentration of bortezomib. The proliferative inhibition of treated HL-60 cell was analysed by MTT assay. The cell apoptosis was determined by flow cytometry with Annexin V/PI double staining and the expression of caspase-8 was detected by Western blot. The results showed that the subtoxic concentration of bortezomib combined with 10 ng/ml of TRAIL enhanced apoptosis of HL-60 cells, as compared with TRAIL used alone; the expression of caspase-8 increased correspondingly. It is concluded that subtoxic concentration of bortezomib can sensitize HL-60 cells to TRAIL and its mechanism may be related to upregulation of caspase-8 expression.",
        "keywords": [
            "trail",
            "apoptosis",
            "bortezomib",
            "leukemia"
        ],
        "authors": [
            {
                "name": "Rong Hu",
                "org": "Department of Hematology,Shengjing Hospital,China Medical University,Shenyang ,Liaoning Province,China"
            },
            {
                "name": "Rong Zhang",
                "org": "Department of Hematology,Shengjing Hospital,China Medical University,Shenyang ,Liaoning Province,China"
            },
            {
                "name": "Ying-Chun Li",
                "org": "Department of Hematology,Shengjing Hospital,China Medical University,Shenyang ,Liaoning Province,China"
            },
            {
                "name": "Kun Yao",
                "org": "Department of Hematology,Shengjing Hospital,China Medical University,Shenyang ,Liaoning Province,China"
            },
            {
                "name": "Ying Yang",
                "org": "Department of Hematology,Shengjing Hospital,China Medical University,Shenyang ,Liaoning Province,China"
            },
            {
                "name": "Si-Yuan Hou",
                "org": "Department of Hematology,Shengjing Hospital,China Medical University,Shenyang ,Liaoning Province,China"
            },
            {
                "name": "Wei Yang",
                "org": "Department of Hematology,Shengjing Hospital,China Medical University,Shenyang ,Liaoning Province,China"
            },
            {
                "name": "Zhuo-Gang Liu",
                "org": "Department of Hematology,Shengjing Hospital,China Medical University,Shenyang ,Liaoning Province,China"
            }
        ],
        "venue": "Zhongguo shi yan xue ye xue za zhi / Zhongguo bing li sheng li xue hui = Journal of experimental hematology / Chinese Association of Pathophysiology",
        "year": 2010
    },
    "JlQEupnN": {
        "id": "JlQEupnN",
        "title": "Clinical Efficacy and Safety of Rituximab Combined with CHOP Chemotherapy for Non-hodgkin Lymphoma:A Meta-analysis",
        "abstract": "OBJECTIVE:To evaluate the clinical efficacy and safety of rituximab combined with CHOP chemotherapy(RCHOP)for non-hodgkin lymphoma.METHODS:Retrieved from Embase(1991～2010),PubMed(1991～2010),CNKI(1991～ 2010)and CBM(1991～2010),RCTs on rituximab combined with CHOP chemotherapy for non-hodgkin lymphoma were collected and quality evaluation was carried out.RESULTS:8 RCTs involving 1 632 patients were included.Results of Meta-analysis showed that significant differences were found in the total effective rate [RR=1.16,95%CI(1.11,1.22]) and complete remission rate [RR=1.34,95%CI(1.19,1.51)],but not in the incidence of Ⅲ/Ⅳ grade chemotherapy-related ADR between RCHOP chemo-therapy and CHOP chemotherapy.CONCLUSION:Compared with CHOP chemotherapy,rituximab combined with CHOP chemo-therapy for non-hodgkin lymphoma can improve the total effective rate and complete remission rate.Meanwhile,it doesnt’ increase the incidence of Ⅲ/Ⅳ grade chemotherapy-related ADR.",
        "keywords": [
            "RCTs",
            "Rituximab",
            "Meta-analysis",
            "Non-hodgkin lymphoma"
        ],
        "authors": [
            {
                "name": "LI Yang",
                "org": "Hematopathy Therapeutic Center,Shengjing Hospital of China Medical University,Shenyang ,China"
            },
            {
                "name": "YANG Wei",
                "org": "Hematopathy Therapeutic Center,Shengjing Hospital of China Medical University,Shenyang ,China"
            },
            {
                "name": "PAN Meng-yao",
                "org": "Hematopathy Therapeutic Center,Shengjing Hospital of China Medical University,Shenyang ,China"
            },
            {
                "name": "XU Shu-mei",
                "org": "Hematopathy Therapeutic Center,Shengjing Hospital of China Medical University,Shenyang ,China"
            },
            {
                "name": "LIU Zhuo-gang",
                "org": "Hematopathy Therapeutic Center,Shengjing Hospital of China Medical University,Shenyang ,China"
            }
        ],
        "venue": "China Pharmacy",
        "year": 2010
    },
    "bVwOisOq": {
        "id": "bVwOisOq",
        "title": "Embelin Overcome the Resistance of K562/D to Daunorubicin",
        "abstract": "Objective To illustrate embelin could overcome the resistance of leukemia drug-resistant cell line K562/D to daunorubcin(DNR).Methods IC10 of embelin on K562/D after 24 hours,resistance index and reverse fold were observed by MTT assay.Apoptosis rates of cells were observed by annexin Ⅴ FITC/PI double staining and flow cytometry.Mitochondrial menmbrane potential(△Ψm)were observed by JC-1 staining and flow cytometry.Results K562/D is resistant to DNR and resistance index is 7.72.Small dosage embelin(5 μg/ml)could reverse the resistance of K562/D to DNR and reverse fold is 7.46.△Ψm appears obvious depolarization 6 hours after embelin(5 μg/ml)in combination with DNR(0.1 μg/ml)on K562/D.Increase of apoposis rates is time-dependen(twith statistical significance compared to control group).Conclusion Embelin could overcome the resistance of K562/D to DNR.△Ψm depolarization appears ahead of apoptosis showing that apoptosis couldn't be reversed.",
        "keywords": [
            "apoptosis",
            "resistance",
            "mitochondrial membrane potential",
            "embelin"
        ],
        "authors": [
            {
                "name": "HU Rong",
                "org": "Department of Hematology,Shengjing Hospital,China Medical University,Shenyang ,China"
            },
            {
                "name": "ZHU Ke",
                "org": "Department of Hematology,Shengjing Hospital,China Medical University,Shenyang ,China"
            },
            {
                "name": "ZHANG Xiao-yue",
                "org": "The 95K,Clinical Medicine,Seven-year System,China Medical University,Shenyang ,China"
            },
            {
                "name": "YANG Ying",
                "org": "Department of Hematology,Shengjing Hospital,China Medical University,Shenyang ,China"
            },
            {
                "name": "HOU Si-yuan",
                "org": "Department of Hematology,Shengjing Hospital,China Medical University,Shenyang ,China"
            },
            {
                "name": "YANG Wei",
                "org": "Department of Hematology,Shengjing Hospital,China Medical University,Shenyang ,China"
            },
            {
                "name": "LIU Zhuo-gang",
                "org": "Department of Hematology,Shengjing Hospital,China Medical University,Shenyang ,China"
            }
        ],
        "venue": "Journal of China Medical University",
        "year": 2010
    },
    "SfvgvkLb": {
        "id": "SfvgvkLb",
        "title": "Apoptosis of jurkat cells induced by ursolic acid and its mechanism]",
        "abstract": "The aim of this study was to investigate the apoptosis effect of Jurkat cells induced by ursolic acid (UA) and its molecular mechanism so as to provide the theoretical basis for treatment of hematological malignancies by using UA. The cytotoxic effect of different concentration UA on Jurkat cells and inhibitory effect of caspase-9 inhibitor on cytotoxicity of UA were assayed by using WST-8 method; the Jurkat cells treated with 20 or 40 micromol/L UA for 2 or 4 hours were collected and were stained by Annexin/PI, then the apoptosis rate of Jurkat cells was detected by flow cytometry; the Jurkat cells in logarithmic growth phase were collected after treatment with different concentrations of UA for different times, the cell protein was extracted, then the activation of caspase-9, -3 and cytochrome C as well as phosphorylation level of Akt were determined by Western blot. The results indicated that the cytotoxic effect of UA on Jurkat cells was significant. UA induced apoptosis of Jurkat cells. Caspase-9, caspase-3 and cytochrome C were activated, and the phosphorylation of Akt was inhibited in the Jurkat cell apoptosis process induced by UA. It is concluded that the UA shows significant cytotoxic effect on Jurkat cells, UA can induce apoptosis of Jurkat cells through the mitochondria pathway. The mechanism may be associated with the inhibition of Akt phosphorylation.",
        "keywords": [
            "ursolic acid",
            "apoptosis",
            "jurkat cell"
        ],
        "authors": [
            {
                "name": "Bin Wu",
                "org": " Department of Hematology,Shengjing Hospital,China Medical University,Shenyang ,Liaoning Province,China,1Endoscopy Center,China Medical University First Hospital,Shenyang ,Liaoning Province,China"
            },
            {
                "name": "Xu Wang",
                "org": " Department of Hematology,Shengjing Hospital,China Medical University,Shenyang ,Liaoning Province,China,1Endoscopy Center,China Medical University First Hospital,Shenyang ,Liaoning Province,China"
            },
            {
                "name": "Hui-Han Wang",
                "org": " Department of Hematology,Shengjing Hospital,China Medical University,Shenyang ,Liaoning Province,China,1Endoscopy Center,China Medical University First Hospital,Shenyang ,Liaoning Province,China"
            },
            {
                "name": "Hong-Tao Wang",
                "org": " Department of Hematology,Shengjing Hospital,China Medical University,Shenyang ,Liaoning Province,China,1Endoscopy Center,China Medical University First Hospital,Shenyang ,Liaoning Province,China"
            },
            {
                "name": "Wei Yang",
                "org": " Department of Hematology,Shengjing Hospital,China Medical University,Shenyang ,Liaoning Province,China,1Endoscopy Center,China Medical University First Hospital,Shenyang ,Liaoning Province,China"
            },
            {
                "name": "Zuo-Fei Chi",
                "org": " Department of Hematology,Shengjing Hospital,China Medical University,Shenyang ,Liaoning Province,China,1Endoscopy Center,China Medical University First Hospital,Shenyang ,Liaoning Province,China"
            },
            {
                "name": "Zhuo-Gang Liu",
                "org": " Department of Hematology,Shengjing Hospital,China Medical University,Shenyang ,Liaoning Province,China,1Endoscopy Center,China Medical University First Hospital,Shenyang ,Liaoning Province,China"
            }
        ],
        "venue": "Zhongguo shi yan xue ye xue za zhi / Zhongguo bing li sheng li xue hui = Journal of experimental hematology / Chinese Association of Pathophysiology",
        "year": 2010
    },
    "7IXJsuT1": {
        "id": "7IXJsuT1",
        "title": "Effect of Embelin on proliferation, differentiation and aopotosis of HL-60 cells.",
        "abstract": "OBJECTIVE: To study the effect of embelin on proliferation, differentiation and apoptosis of HL-60 cells and explore its possible mechanism. METHODS: Different concentration of embelin were used to treat HL-60 cells. Cell growth curve was analysed by MTT assay, cell apoptosis by Annexin V/PI double staining and JC-1 dye. The differentiation of HL-60 cells was evaluated by expression of CD33, CD34, CD11b and CD14. Bone marrow cells (BMC) from nine patients with acute nonlymphocytic leukemia (ANML) were also studied. RESULTS: Embelin induced differentiation of HL-60 cells with significant increase of CD14 and CD11b expression at 33.97µmol/L for 3 days (P < 0.01). Embelin induced apoptosis of HL-60 cells in a time- and dose-dependent manner, the apoptosis rates were (9.23 ± 0.05)%, (25.86 ± 0.30)% and (39.03 ± 0.07)% respectively at 339.67 µmol/L of embelin for 12-, 24- and 48-hours treatment (P < 0.05); the apoptosis rates were (0.07 ± 0.03)%, (7.43 ± 0.30)%, (14.01 ± 0.01)%, (25.52 ± 0.03)% and (39.15 ± 0.01)% respectively at 10.19, 33.97, 101.90, 339.67 and 1019.02 µmol/L of embelin for 24-hours culture (P < 0.05). Clusters of differentiation antigen on BMC from three acute promyelocytic leukemia patients showed significant changes at 33.97 µmol/L of embelin treatment for 3 days. Embelin induced apoptosis of BMCs from all the nine ANML patients at 33.97 µmol/L for 24 hour. CONCLUSION: Embelin can inhibit proliferation and induce differentiation and apoptosis of HL-60 cells. The mechanism may be related to mitochondrial apoptosis pathway. Embelin at subtoxic concentration doesn't promote leukemia BMC differentiation, but at 339.67 µmol/L induces apoptosis of these cells.",
        "keywords": [],
        "authors": [
            {
                "name": "Rong Hu",
                "org": "Department of Hematology, Shengjing Hospital, China Medical University, Shenyang 110021, China."
            },
            {
                "name": "Bin Wu",
                "org": ""
            },
            {
                "name": "Guo-Jun Zhang",
                "org": ""
            },
            {
                "name": "Hong-Tao Wang",
                "org": ""
            },
            {
                "name": "Ke Zhu",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Zhuo-Gang Liu",
                "org": ""
            }
        ],
        "venue": "Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi",
        "year": 2010
    },
    "qjxKeA9k": {
        "id": "qjxKeA9k",
        "title": "Cytomegalovirus infections after hemotopoietic stem cell transplantation in leukemia patients: a meta-analysis of clinical cases",
        "abstract": "null",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "CHEN Bo",
                "org": "Department of Hematology,Shengjing Affiliated Hospital of China Medical University,Shenyang ,China"
            },
            {
                "name": "YANG Wei",
                "org": "Department of Hematology,Shengjing Affiliated Hospital of China Medical University,Shenyang ,China"
            }
        ],
        "venue": "Chinese Journal of Infection and Chemotherapy",
        "year": 2011
    },
    "3ls6XeKP": {
        "id": "3ls6XeKP",
        "title": "Two cases of bilateral ovary diffuse large B-cell non Hodgkin's lymphoma",
        "abstract": "",
        "keywords": [
            "ovary",
            "diffuse large B-cell",
            "non Hodgkin's lymphoma"
        ],
        "authors": [
            {
                "name": "CHEN Bo",
                "org": ".Blood Treatment Center,Shengjing Affiliated Hospital of China Medical University,Shenyang ,China"
            },
            {
                "name": "YANG Wei",
                "org": ".Blood Treatment Center,Shengjing Affiliated Hospital of China Medical University,Shenyang ,China"
            }
        ],
        "venue": "Chinese Journal of Practical Internal Medicine",
        "year": 2011
    },
    "4aNkqbty": {
        "id": "4aNkqbty",
        "title": "Comparison of FLAG regimen with CAG regimen for refractory or relapsed acute myeloid leukemia",
        "abstract": "Objective:To investigate the efficacy and safety of FLAG and CAG regimen for refractory or released acute myeloid leukemia(AML).Methods: Seventy-four patients with refractory or released AML in our hospital were divided into FLAG group and CAG group.The efficacy and toxicities were analyzed and compared between the two groups.Results: The complete remission rate(CR) was 61.5% and the overall response(OR) rate was 76.9% in FLAG group.The CR rate was 35.4% and the OR rate was 50% in CAG group.For the patients with primary refractory AML or relapsed AML or refractory or relapsed AML of M1,M2,M5 subtype or those converted from myelodysplastic syndrome(MDS),the rate of CR and OR in FLAG group was higher than that in CAG group.The main toxicities of these two groups were myelosuppression.Conclusion: FLAG regimen and CAG regimen are both effective for refractory or relapsed AML,but the rate of CR and OR in FLAG group was higher,and the adverse effects from FLAG regimen were well tolerated by patients,so the FLAG regimen can be widely used further.",
        "keywords": [
            "toxicities",
            "CAG regimen",
            "FLAG regimen",
            "refractory AML",
            "relapsed AML",
            "efficacy"
        ],
        "authors": [
            {
                "name": "LI Jia",
                "org": " Department of Hematology,Shengjing Hospital of China Medical University,Liaoning Shenyang ,China"
            },
            {
                "name": "HU Rong",
                "org": " Department of Hematology,Shengjing Hospital of China Medical University,Liaoning Shenyang ,China"
            },
            {
                "name": "LIAO Aijun",
                "org": " Department of Hematology,Shengjing Hospital of China Medical University,Liaoning Shenyang ,China"
            },
            {
                "name": "YANG Ying",
                "org": " Department of Hematology,Shengjing Hospital of China Medical University,Liaoning Shenyang ,China"
            },
            {
                "name": "YANG Wei",
                "org": " Department of Hematology,Shengjing Hospital of China Medical University,Liaoning Shenyang ,China"
            },
            {
                "name": "LIU Zhuogang",
                "org": " Department of Hematology,Shengjing Hospital of China Medical University,Liaoning Shenyang ,China"
            }
        ],
        "venue": "Journal of Modern Oncology",
        "year": 2011
    },
    "4lFhA7Mz": {
        "id": "4lFhA7Mz",
        "title": "Effects of different time points of bortezomib on the pathway of NF-κB in drug-resistant K562 cells",
        "abstract": "Objective To study the effects of bortezomib on the expression of NF--κB, I-κB and P-gp of drug-resistant K562 cells induced by daunorubicin (K562/DNR), to explore the molecular mechanism of drug-resistant reverse. Methods The expression of NF-κ, IkB and P-gp in K562/DNR cells were detected when the cells had been treated with 100 μg/ml DNR only or together with 4μg/L bortezomib for 12 h, 24 h and 36 h. The apoptosis rates were detected in each group respectively and the activity of NF-κ was detected by ELISA method. Results Compared with the control group, the expressions of NF-κ and P-gp in K562/ DNR could be increased and IkB was decreased after being treated with DNR. When K562/DNR were cultured with bortezomib, the expressions of NF-κ and P-gp induced by DNR were significantly suppressed and IkB was increased. The activity of NF-κ were detected in different time points: (15.3±1.87) % [(23.8± 2.27) % in DNR group] at 12 h, (10.2±1.69) % [(25.4±1.98) % in DNR group]- at 24 h, (6.08±2.53) % [(26.9± 2.58) % in DNR group]- at 36 h. There were a significant differences between DNR group and DNR341 group. The apoptosis rates were increased in DNR341 group at different time points than those in DNR group, (35.23±5.15) % [(15.56±4.12) % in DNR group]- at 12 h, (40.26±6.89) % [(17.25±2.89) % in DNR group]- at 24 h, (43.58±7.69) % [(22.47±4.58) % in DNR group]- at 36 h. The effcets showed the character of time-dependent pattern. Conclusion Bortezomib could downregulate the expressions of NF-κ and P-gp in K562/DNR, reverse the drug resistance and up-regulate the apoptotic rates in K562/DNR cells.",
        "keywords": [
            "Drug-resistant",
            "IκB proteins",
            "NF-κB",
            "P-glycoprotein",
            "Proteasome inhibitor"
        ],
        "authors": [
            {
                "name": "Aijun Liao",
                "org": "China Medical University Shenyang(China Medical University),Shenyang,China"
            },
            {
                "name": "BeiBei Fu",
                "org": "China Medical University Shenyang(China Medical University),Shenyang,China"
            },
            {
                "name": "Yingchun Li",
                "org": "China Medical University Shenyang(China Medical University),Shenyang,China"
            },
            {
                "name": "Huihan Wang",
                "org": "China Medical University Shenyang(China Medical University),Shenyang,China"
            },
            {
                "name": "Yang Wei",
                "org": "China Medical University Shenyang(China Medical University),Shenyang,China"
            },
            {
                "name": "Zhuogang Liu",
                "org": "China Medical University Shenyang(China Medical University),Shenyang,China"
            }
        ],
        "venue": "Journal of Leukemia and Lymphoma",
        "year": 2011
    },
    "yEKz0tmX": {
        "id": "yEKz0tmX",
        "title": "The study of FTY720 on inducing apoptosis and autophagy in multiple myeloma cell line U266]",
        "abstract": "To investigate the effects of FTY720, a new immunosuppressive agent, on apoptosis and autophagy in multiple myeloma(MM) cell line U266 and to clarify its molecular mechanism.U266 cells were treated with 0, 2.5, 5.0, 10.0 and 20.0 µmol/L FTY720 for 24 hours, and the cell viability was assayed by CCK-8 method. Then U266 cells were treated with 20.0 µmol/L FTY720 for 0, 2, 6 and 24 hours, the cell viability was tested. The apoptotic rates induced by different doses and time points of FTY720 were tested by flow cytometry separately. The expression of LC3B was detected by Western blot after U266 cells treated with different doses of FTY720 to see autophagy. U266 cells were treated with FTY720 ± Bafilomycin A1, an inhibitor of autophagy, for 24 hours, then the cell viability and apoptotic rates were tested. Meanwhile the expression of survivin, anti-apoptotic factors, were tested by Western blot.The cell viability and the apoptotic rates were inhibited significantly by FTY720 (P < 0.05) in time-dependent and dose-dependent manner. The expression of LC3B-II increased significantly in a dose-dependent manner, it indicated that the autophagy was induced by FTY720. Bafilomycin A1 could rescue the cell viability and apoptotic rates in U266 cells treated with FTY720, and it could also rescue the expression of survivin decreased by FTY720.FTY720 can cause apoptosis and autophagy of U266 cells. The autophagy promote the apoptosis, which maybe due to the degradation of anti-apoptotic factors such as survivin or their upstream factors in lysosomes through autophagy.",
        "keywords": [],
        "authors": [
            {
                "name": "Ai-jun Liao",
                "org": "Department of Hematology, China Medical University, Shenyang, China."
            },
            {
                "name": "Rong Hu",
                "org": ""
            },
            {
                "name": "Ying-chun Li",
                "org": ""
            },
            {
                "name": "Kun Yao",
                "org": ""
            },
            {
                "name": "Hui-han Wang",
                "org": ""
            },
            {
                "name": "Rong Zhang",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Zhuo-gang Liu",
                "org": ""
            }
        ],
        "venue": "Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi",
        "year": 2011
    },
    "fSbwCFWl": {
        "id": "fSbwCFWl",
        "title": "Rituximab Combined with CHOP Chemotherapy for Non-Hodgkin Lymphoma:A Meta-analysis",
        "abstract": "Objective To evaluate the curative effect of Rituxmiab combined with CHOP chemotherapy on non-Hodgkin Lymphoma in China.Methods Systematic review method of \"The Cochrane Collaboration\" was used to collect,by computer retrieves,randomized controlled trials of Rituximab combined with CHOP for non-Hodgkin Lymphoma.The methodological quality of the included studies was evaluated,and data analyses were performed using Rev Man 4.2 software.Results A total of 7 literatures were enrolled,including 357 patients.There was homogeneity among all literatures,using fixed effect model,OR=3.02,95%CI(1.94,4.72).There was significant difference in complete remission rate between combined CHOP group and single-used CHOP protocol group(P<0.01).Conclusion So far,domestic protocol of combined rituximab and CHOP chemotherapy is of some curative effects on non-Hodgkin lymphoma.But due to small and low-quality samples,large and high-quality samples are needed to confirm the above conclusions.",
        "keywords": [
            "Treatment outcome",
            "Meta-analysis",
            "non-Hodgkin",
            "Lymphoma",
            "Rituxmiab"
        ],
        "authors": [
            {
                "name": "HOU Si-yuan",
                "org": ".Department of Hematology,Affiliated Shengjing Hospital of China Medical University,Shenyang ,China"
            },
            {
                "name": "YANG Wei",
                "org": ".Department of Hematology,Affiliated Shengjing Hospital of China Medical University,Shenyang ,China"
            }
        ],
        "venue": "Chinese General Practice",
        "year": 2011
    },
    "2DGJkj49": {
        "id": "2DGJkj49",
        "title": "Effectiveness and Safety of Rituximab Plus CHOP Chemotherapy for Treating Non-Hodgkin Lymphoma Among Chinese People: A Meta-Analysis",
        "abstract": "Objective To assess the effectiveness and safety of Rituximab plus CHOP chemotherapy for treating non-Hodgkin lymphoma among Chinese people. Methods Using the words \"Rituximab\", \"non-hodgkin lymphoma\", \"systematic review\", \"meta-analysis\", \"randomized controlled trial\" as searching words, we searched CNKI(1991-2010), CBM(1991-2010), VIP(1991-2010) and WANGFANG(1991-2010) databases. We also hand searched the relevant references of included studies and review. Randomized controlled trials performed in China on rituximab plus CHOP chemotherapy for treating non-Hodgkin lymphoma were collected. Two reviewers independently screened trails,evaluated the quality of included trials and extracted data. The Cochrane Collaboration?s RevMan 4.2 software was used for statistical analysis. Results Four trails involving 218 patients were included. Results of meta-analyses showed that significant differences were found in the total effective rate (RR=1.22, 95%CI 1.04～1.44) and complete remission rate (RR=1.32, 95%CI 1.01～1.73), but not in the major chemotherapy-related adverse reactions (leukocytopenia, thrombocytopenia, nausea/vomiting, liver-damage) between rituximab plus CHOP and CHOP alone. Conclusion Based on the present domestic trails, compared with CHOP chemotherapy, treatment for non-Hodgkin lymphoma with Rituximab plus CHOP chemotherapy can improve the total effective rate and the complete remission rate and meanwhile it doesn?t increase the adverse reactions. However, because of the low quality and small sample of included RCTs, more large-sample, well-designed, exactly-performed, double-blind, randomized and controlled trials are still required.",
        "keywords": [
            "meta-analysis",
            "randomized controlled trial",
            "Rituximab",
            "non-Hodgkin lymphoma"
        ],
        "authors": [
            {
                "name": "LI Yang",
                "org": "Center for Hematology"
            },
            {
                "name": "LIU Zhuo-gang",
                "org": "Center for Hematology"
            },
            {
                "name": "HAO Liang-chun",
                "org": "Center for Hematology"
            },
            {
                "name": "YANG Wei",
                "org": "Center for Hematology"
            },
            {
                "name": "WANG Zhan-qiang",
                "org": "Department of Neurology,Affiliated Shengjing Hospital of China Medical University,Shenyang ,China"
            },
            {
                "name": "XU Shu-mei",
                "org": "Center for Hematology"
            }
        ],
        "venue": "The Journal of Evidence-Based Medicine",
        "year": 2011
    },
    "CprZ80Zr": {
        "id": "CprZ80Zr",
        "title": "Study on mechanism of bortezomib inducing peripheral neuropathy and the reversing effect of reduced glutathione]",
        "abstract": "To study the mechanism of bortezomib inducing peripheral neuropathy and the reversing affection of reduced glutathione.Female Wistar rats were randomly divided into three groups. Group 1, treatment with bortezomib; Group 2, treatment with bortezomib and reduced glutathione; Group 3, saline control group. Drugs were administrated on the 1st, 4th, 7th and 11th day for the three groups. The amorphous of sciatic nerve and dorsal root ganglion (DRG) were observed by electron microscope on 14th and 42nd day. On 14th day, laser confocal microscopy was used to detect reactive oxygen species (ROS) of DRG neuron obtained from the rats by treated with DCFH-DA after primary culture.On 14th day, morphology of sciatic nerve and DRG changed in both group 1 and 2. On 42nd day, the amorphous became normally in group 1. On 14th day, ROS releasing from DRG neuron was increased obviously in group 1 (P < 0.01), while decreased in both group 2 and 3, and the difference between the latter two groups had no statistical significance (P = 0.210).Releasing ROS to injure mitochondrion and endoplasmic reticulum maybe involved in bortezomib induced peripheral neuropathy. Although reduced glutathione can inhibit ROS release, it has no obviously reversal effect for peripheral neuropathy.",
        "keywords": [],
        "authors": [
            {
                "name": "Hong-tao Wang",
                "org": "Hematology Malignancy Treatment Center, Sheng Jing Hospital, China Medical University, Shenyang 110022, China."
            },
            {
                "name": "Zhuo-gang Liu",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Ai-jun Liao",
                "org": ""
            },
            {
                "name": "Rong Zhang",
                "org": ""
            },
            {
                "name": "Bin Wu",
                "org": ""
            },
            {
                "name": "Hui-han Wang",
                "org": ""
            },
            {
                "name": "Kun Yao",
                "org": ""
            },
            {
                "name": "Ying-chun Li",
                "org": ""
            }
        ],
        "venue": "Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi",
        "year": 2011
    },
    "a5WJoBA3": {
        "id": "a5WJoBA3",
        "title": "Influencing factors of induction treatment of arsenic trioxide in combination with all-trans retinoic acid in patients with newly diagnosed acute promyelocytic leukemia",
        "abstract": "Objective:To observe the therapeutic effect of arsenic trioxide(ATO)in combination with all-transretinoic acid(ATRA) in treatment of newly diagnosed acute promyelocytic leukemia(APL),and analyze the influencing factors of induction treatment.Methods:Total of 98 newly diagnosed APL patients treated by both ATO and ATRA were divided by age,gender,WBC count,LDH,morphological subtypes,fusion gene types and different chromosome types.Results: In the 98 patients,CR rate was 89% and CR achieving time was 30.5(19-42)d.Older,higher WBC,LDH higher,S-type isoform typical karytype,additional karyotype groups had the lower CR rate,longer CR achieving time,while with t(15;17)(q22;q21),L-type isoform typical karytype had the different results.Conclusion: Age,initial WBC count,LDH,morphological subtypes,additional karyotype,fusion gene types are important influencing factors for CR in patients with newly diagnosed APL treated by ATRA in combination with ATO.",
        "keywords": [
            "prognostic factor",
            "combined treatment",
            "arsenic trioxide",
            "all-trans retinoic acid",
            "acute promyelocytic leukemia"
        ],
        "authors": [
            {
                "name": "YAN Wei",
                "org": " Department of Hematology,Affiliated Shengjing Hospital of China Medical University,Liaoning Shenyang ,China."
            },
            {
                "name": "HU Wenxu",
                "org": " Department of Hematology,Affiliated Shengjing Hospital of China Medical University,Liaoning Shenyang ,China."
            },
            {
                "name": "YANG Wei",
                "org": " Department of Hematology,Affiliated Shengjing Hospital of China Medical University,Liaoning Shenyang ,China."
            }
        ],
        "venue": "Journal of Modern Oncology",
        "year": 2012
    },
    "BvhA55BV": {
        "id": "BvhA55BV",
        "title": "The proteasome inhibitor bortezomib reverses P-glycoprotein-mediated leukemia multi-drug resistance through the NF-kappaB pathway.",
        "abstract": "Multi-drug resistance (MDR) is one of the obstacles for leukemia therapy, the major cause is an overexpression of P-glycoprotein (P-gp) leading to increased drug efflux. We investigated the reversion of multi-drug resistance and the possible mechanism by which the proteasome inhibitor bortezomib affects the expression of the multi-drug resistance gene mdrl in the K562/DNR cell line. The drug resistance of the cells and the cellular toxicity of bortezomib were confirmed by MTT. Intracellular drug concentrations and cell apoptosis were detected by flow cytometry. The expression of mdrl mRNA was examined by fluorescence quantitative PCR. The expression levels of nuclear factor-kappa B (NF-kappaB), inhibitor of NF-kappaB (IkappaB) and P-gp were detected by western blotting, and NF-kappaB activity was detected by ELISA. DNR-induced apoptosis increased in a dose-dependent manner after adding bortezomib. Bortezomib decreased IkappaB degradation, decreased NF-kappaB and NF-kappaB p65 activity, reduced P-gp/mdr1 mRNA expression, and increased the intracellular DNR concentration in K562/DNR cells in vitro. The bortezomib reversed leukemic multi-drug resistance in a dose-dependent manner as the result of decreasing IkappaB degradation, thus preventing the translocation of NF-kappaB into the nucleus and leading the down-regulation of mdr1 and a reduction in P-gp expression. Therefore, the intracellular drug concentration increased, and then apoptosis was induced.",
        "keywords": [],
        "authors": [
            {
                "name": "Huihan Wang",
                "org": "Department of Hematology, Shengjing Hospital, China Medical University, Shenyang, Liaoning, China."
            },
            {
                "name": "Xiaobin Wang",
                "org": ""
            },
            {
                "name": "Yingchun Li",
                "org": ""
            },
            {
                "name": "Aijun Liao",
                "org": ""
            },
            {
                "name": "Beibei Fu",
                "org": ""
            },
            {
                "name": "Hongyu Pan",
                "org": ""
            },
            {
                "name": "Zhuogang Liu",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            }
        ],
        "venue": "Die Pharmazie",
        "year": 2012
    },
    "6DIr6Fwv": {
        "id": "6DIr6Fwv",
        "title": "Serum adiponectin,leptin,and resistin in acute myeloid leukemia patients",
        "abstract": "Objective To investigate adiponectin,leptin,and resistin levels at diagnosis and during chemotherapy in patients with acute myeloid leukemia(AML).Methods ABC-ELLSA was used to detect the adiponectin,leptin,and resistin levels in 35 AML patients and 50 normal controls.The corresponding lactate dehydrogenase(LDH) levels were also recorded.Results At diagnosis,mean adiponectin and resistin levels were low compared with controls(P<0.001),but the leptin levels had no difference(P=0.368).During the chemotherapy,adiponectin and resistin increased significantly(P<0.001),and the leptin levels still had no significant difference(P=0.849).The levels of adiponectin and resistin were negatively correlated with LDH during therapy(r=-0.539,P=0.005 and r=-0.587,P=0.005,respectively).Conclusion Low adiponectin and resistin are present at the AML diagnosis.Those two adipocytokines alterations are progressively restored during therapy.Whereas the serum leptin is not correlated with AML.",
        "keywords": [
            "Leptin",
            "Acute myeloid leukemia",
            "Adiponectin",
            "Resistin"
        ],
        "authors": [
            {
                "name": "ZHANG Ying",
                "org": "Department of Haematology,the People’s Hospital of Liaoning Province,Liaoning Shenyang "
            },
            {
                "name": "YANG Wei",
                "org": "Department of Haematology,Shengjing Hospital of China Medical University,Liaoning Shenyang "
            },
            {
                "name": "LIU Dong-mei",
                "org": "Department of Haematology,the People’s Hospital of Liaoning Province,Liaoning Shenyang "
            }
        ],
        "venue": "Jilin Medical Journal",
        "year": 2012
    },
    "GSn0yV81": {
        "id": "GSn0yV81",
        "title": "Effect of Embelin on MMP-9 mRNA,NF-κB and VEGF expression in HL-60 cells",
        "abstract": "Objective:To investigate the effect of Embelin on matrix metalloproteinase-9(MMP-9) mRNA,vascular endothelial growth factor(VEGF) and NF-κB expression in HL-60 cells and explore the relation between them.Methods: The expression of MMP-9 mRNA was detected by Real time-PCR,and VEGF and NF-κB by Western blot.Results: Embelin could inhibit the NF-κB,MMP-9 mRNA and VEGF expression in HL-60 cells in a dose-dependent manner.Conclusion: Embelin could downregulate MMP-9 mRNA,NF-κB and VEGF expression in HL-60 cells and may reduce the invasiveness of leukemia cells.",
        "keywords": [
            "vascular endothelial growth factor",
            "Embelin",
            "matrix metalloproteinase-9",
            "leukemia",
            "NF-κB"
        ],
        "authors": [
            {
                "name": "HU Rong",
                "org": "Department of Hematology,Shengjing Hospital,China Medical Universtiy,Liaoning Shenyang ,China"
            },
            {
                "name": "YANG Ying",
                "org": "Department of Hematology,Shengjing Hospital,China Medical Universtiy,Liaoning Shenyang ,China"
            },
            {
                "name": "LI Jia",
                "org": "Department of Hematology,Shengjing Hospital,China Medical Universtiy,Liaoning Shenyang ,China"
            },
            {
                "name": "MIAO Miao",
                "org": "Department of Hematology,Shengjing Hospital,China Medical Universtiy,Liaoning Shenyang ,China"
            },
            {
                "name": "ZHU Ke",
                "org": "Department of Hematology,Shengjing Hospital,China Medical Universtiy,Liaoning Shenyang ,China"
            },
            {
                "name": "ZHANG Jihong",
                "org": "Laboratory of Hematology,Shengjing Hospital,China Medical Universtiy,Liaoning Shenyang ,China"
            },
            {
                "name": "LIAO Aijun",
                "org": "Department of Hematology,Shengjing Hospital,China Medical Universtiy,Liaoning Shenyang ,China"
            },
            {
                "name": "YANG Wei",
                "org": "Department of Hematology,Shengjing Hospital,China Medical Universtiy,Liaoning Shenyang ,China"
            },
            {
                "name": "LIU Zhuogang",
                "org": "Department of Hematology,Shengjing Hospital,China Medical Universtiy,Liaoning Shenyang ,China"
            }
        ],
        "venue": "Journal of Modern Oncology",
        "year": 2012
    },
    "Yi1dEZvR": {
        "id": "Yi1dEZvR",
        "title": "Ursolic acid-induced apoptosis in K562 cells involving upregulation of PTEN gene expression and inactivation of the PI3K/Akt pathway.",
        "abstract": "Ursolic acid (UA), a pentacyclic triterpenoid derived from a variety of medicinal plants, exhibits potent anticancer activity against many types of cancer cells. However, the anticancer mechanism of UA is not clearly understood. Suppression of phosphatase and a tensin homolog deleted on chromosome 10 (PTEN) gene expression leading to activation of the phosphatidylinositol-3-OH kinase (PI3K)/Akt pathway has been observed in many cancers including leukemia, making the PTEN gene and PI3K/Akt pathway a central target for cancer therapy. Here, we demonstrated that UA was able to inhibit growth, induce apoptosis in a human chronic myelogenous leukemia cell line (K562 cells) via upregulation of PTEN gene expression, inhibit Akt kinase activity, change mitochondrial transmembrane potential and reduce the release of cytochrome c and the activity of caspases. These results suggest that UA may elicit its strong antitumor effects via upregulation of the PTEN gene and inhibition of the PI3K/Akt pathway.",
        "keywords": [
            "apoptosis",
            "k562",
            "pten",
            "ursolic acid"
        ],
        "authors": [
            {
                "name": "Bin Wu",
                "org": "China Medical University Shenyang(China Medical University),Shenyang,China"
            },
            {
                "name": "Xu Wang",
                "org": "China Medical University Shenyang(China Medical University),Shenyang,China"
            },
            {
                "name": "Zuo-fei Chi",
                "org": "China Medical University Shenyang(China Medical University),Shenyang,China"
            },
            {
                "name": "Rong Hu",
                "org": "China Medical University Shenyang(China Medical University),Shenyang,China"
            },
            {
                "name": "Rong Zhang",
                "org": "China Medical University Shenyang(China Medical University),Shenyang,China"
            },
            {
                "name": "Wei Yang",
                "org": "China Medical University Shenyang(China Medical University),Shenyang,China"
            },
            {
                "name": "Zhuo-gang Liu",
                "org": "China Medical University Shenyang(China Medical University),Shenyang,China"
            }
        ],
        "venue": "Archives of pharmacal research",
        "year": 2012
    },
    "hU87VOL3": {
        "id": "hU87VOL3",
        "title": "A case report of polycythaemia vera transforming to acute leukaemia with literature review",
        "abstract": "",
        "keywords": [
            "acute leukemia",
            "anemia",
            "polycythemia vera",
            "interteukin increased"
        ],
        "authors": [
            {
                "name": "MIAO Miao",
                "org": ""
            },
            {
                "name": "HU Rong",
                "org": ""
            },
            {
                "name": "YANG Wei",
                "org": ""
            }
        ],
        "venue": "Chinese Journal of Practical Internal Medicine",
        "year": 2012
    },
    "AC539ExL": {
        "id": "AC539ExL",
        "title": "Clinical analysis on 10 patients with multiple myeloma treated with once-weekly administration of bortezomib",
        "abstract": "Objective:To investigate the efficacy and adverse effects of once-weekly administration of bortezomib,a chemotherapy regimen in the treatment of multiple myeloma(MM).Methods: The retrospective analysis was based on 10 cases of multiple myeloma with once-weekly administration of bortezomib.There were 6 cases newly diagnosed,and 4 cases treated diagnosed.All patients were treated with once-weekly administration of bortezomib:bortezomib 1.3mg/m2 was intravenous injection at the 1st,8th,15th and 22nd day,thalidomide 75mg was taken orally once a day(35 days),and dexamethasone 15mg was intravenous injection at the 1st,2nd,8th,9th,15th,16th,21st and 22nd day.The patients who completed at least two courses were evaluated.Results: All 10 patients received once-weekly administration of bortezomib.Seven cases could be evaluated with CR of 6 and VGPR of 1.The adverse effect was mainly herpes zoster(2/7).Conclusion: The effect of once-weekly administration of bortezomib to treat newly diagnosed multiple myeloma is good with less adverse effects and the advantage for the treatment of relapsed multiple myeloma needs further evaluation.",
        "keywords": [
            "multiple myeloma",
            "adverse effects",
            "bortezomib",
            "efficacy",
            "once-weekly administration"
        ],
        "authors": [
            {
                "name": "HU Rong",
                "org": "Hematology Department,Shengjing Hospital,China Medical University,Liaoning Shenyang ,China"
            },
            {
                "name": "HU Wenxu",
                "org": "Hematology Department,Shengjing Hospital,China Medical University,Liaoning Shenyang ,China"
            },
            {
                "name": "GUO Pu",
                "org": "Medical Administration Division,General Hospital of Liaohua in Liaoyang,Liaoning Liaoyang ,China."
            },
            {
                "name": "MIAO Miao",
                "org": "Hematology Department,Shengjing Hospital,China Medical University,Liaoning Shenyang ,China"
            },
            {
                "name": "ZHANG Rong",
                "org": "Hematology Department,Shengjing Hospital,China Medical University,Liaoning Shenyang ,China"
            },
            {
                "name": "LI Yingchun",
                "org": "Hematology Department,Shengjing Hospital,China Medical University,Liaoning Shenyang ,China"
            },
            {
                "name": "LIAO Aijun",
                "org": "Hematology Department,Shengjing Hospital,China Medical University,Liaoning Shenyang ,China"
            },
            {
                "name": "LIU Zhuogang",
                "org": "Hematology Department,Shengjing Hospital,China Medical University,Liaoning Shenyang ,China"
            },
            {
                "name": "YANG Wei",
                "org": "Hematology Department,Shengjing Hospital,China Medical University,Liaoning Shenyang ,China"
            }
        ],
        "venue": "Journal of Modern Oncology",
        "year": 2012
    },
    "Ap9S9Zc4": {
        "id": "Ap9S9Zc4",
        "title": "The Gene Methylation and Protein Expression of SFRP5 in Leukemic Cells",
        "abstract": "Objective To observer the gene methylation and protein expression of SFRP5 in leukemic cells.Methods SFRP5 gene promoter region methylation status of the leukemia patient samples and cell lines were detected by methylation specific PCR(MSP) and bisulfite sequencing PCR(BSP).SFRP5 protein expression was detected by Western blot.Results SFRP5 gene methylation occurred in 7 cases of the total 12 patients,while SFRP5 gene methylation was not detected in 6 normal specimens.SFRP5 gene methylation was observed in leukemia cell line HL-60,Raji,U937 and KG1a.The methylation frequency of SFRP5 gene from-394 bp to +99 bp in KG1a cells was 82.5%.SFRP5 protein expression was detected in all six cases of normal specimens.However,SFRP5 expression was only found in seven cases of leukemia patient samples,but not in the other five cases or leukemia cell lines HL-60,Raji,U937 and KG1a.After demethylating agent 5-aza-2-deoxycytidine(DAC) treatment,the SFRP5 expression in these cell lines was restored.Conclusion SFRP5 gene promoter was methylated in leukemia cells,resulting in SFRP5 protein undetectable or down-regulated.",
        "keywords": [
            "gene methylation",
            "secreted frizzled related protein 5",
            "leukemia"
        ],
        "authors": [
            {
                "name": "WANG Hui-han",
                "org": "Department of Hematology,Shengjing Hospital,China Medical University,Shenyang ,China"
            },
            {
                "name": "ZHANG Guo-jun",
                "org": "Department of Hematology,Shengjing Hospital,China Medical University,Shenyang ,China"
            },
            {
                "name": "YAO Kun",
                "org": "Department of Hematology,Shengjing Hospital,China Medical University,Shenyang ,China"
            },
            {
                "name": "YANG Wei",
                "org": "Department of Hematology,Shengjing Hospital,China Medical University,Shenyang ,China"
            },
            {
                "name": "LIAO Ai-jun",
                "org": "Department of Hematology,Shengjing Hospital,China Medical University,Shenyang ,China"
            },
            {
                "name": "ZHAO Cheng-hai",
                "org": "Department of Pathophysiology,Basic Medical Sciences,China Medical University,Shenyang ,China"
            },
            {
                "name": "LIU Zhuo-gang",
                "org": "Department of Hematology,Shengjing Hospital,China Medical University,Shenyang ,China"
            }
        ],
        "venue": "Journal of China Medical University",
        "year": 2012
    },
    "EYRdhWH4": {
        "id": "EYRdhWH4",
        "title": "Late-onset neutropenia following R-CHOP chemotherapy in B-cell lymphoma",
        "abstract": "Objective:To investigate the incidence and risk factors of late-onset neutropenia(LON) in a uniform group of patients with B-cell lymphoma following curative R-CHOP chemotherapy.Methods: A total of 48 cases of B-cell lymphoma in complete remission(CR)following R-CHOP chemotherapy in our hospital were retrospectively analyzed.Results: As at the last follow-up,13 cases(27.1%) developed LON and 10 cases(20.8%) developed LON of grade III or IV.The median time to neutrophil nadir was 118 days(range 37-165 days).The median time to recovery was 56 days(range 5-212 days) and occurred in all except one patient.No life threatening infection occurred.Results of Fisher exact test revealed that patients with lymphoma in relapse who had already received CHOP chemotherapy or the number of rituximab courses were significantly associated with LON.Conclusion: LON was not common and it was usually self-limiting,and not associated with significant infectious morbidity or mortality.So rituximab can be widely used in B-cell lymphoma.",
        "keywords": [
            "non-Hodgkin's lymphoma",
            "rituximab",
            "infection",
            "neutropenia"
        ],
        "authors": [
            {
                "name": "LI Jia",
                "org": " Department of Hematology,Shengjing Hospital of China Medical University,Liaoning Shenyang ,China."
            },
            {
                "name": "HU Rong",
                "org": " Department of Hematology,Shengjing Hospital of China Medical University,Liaoning Shenyang ,China."
            },
            {
                "name": "LIAO Aijun",
                "org": " Department of Hematology,Shengjing Hospital of China Medical University,Liaoning Shenyang ,China."
            },
            {
                "name": "YANG Ying",
                "org": " Department of Hematology,Shengjing Hospital of China Medical University,Liaoning Shenyang ,China."
            },
            {
                "name": "YANG Wei",
                "org": " Department of Hematology,Shengjing Hospital of China Medical University,Liaoning Shenyang ,China."
            },
            {
                "name": "LIU Zhuogang",
                "org": " Department of Hematology,Shengjing Hospital of China Medical University,Liaoning Shenyang ,China."
            }
        ],
        "venue": "Journal of Modern Oncology",
        "year": 2012
    },
    "0y07r0Zh": {
        "id": "0y07r0Zh",
        "title": "Research progress on imatinib-resistant chronic myeloid leukemia therapy using dasatinib",
        "abstract": "Imatinib is a kind of tyrosine kinase inhibitors and is the first generation targeted molecular medicine used in the treatment of Ph chromosome positive CML.However,gradually appearing of its drug resistance is a big problem in the treatment.The second generation targeted molecular medicine such as dasatinib is more potential for anti-drug resistance.This review is based on these.",
        "keywords": [
            "Chronic myeloid leukemia(CML)",
            "Drug resistance",
            "Dasatinib"
        ],
        "authors": [
            {
                "name": "YAN Wei",
                "org": "Department of Hematology,Shengjing Hospital of China Medical University,Shenyang ,China"
            },
            {
                "name": "YANG Wei",
                "org": "Department of Hematology,Shengjing Hospital of China Medical University,Shenyang ,China"
            }
        ],
        "venue": "Practical Pharmacy and Clinical Remedies",
        "year": 2012
    },
    "qyutwMNE": {
        "id": "qyutwMNE",
        "title": "Mechanisms of ROS in U266 cell death induced by FTY720]",
        "abstract": "This study was purpose to investigate the role of reactive oxygen species (ROS) in apoptosis and autophagy induced by FTY720 in multiple myeloma cell line U266. U266 cells were treated by different concentrations of FTY720 for 24 h, the apoptotic rates were detected by flow cytometry, and the expression of LC3B was detected by Western blot. The results indicated that apoptosis and autophagy were induced by FTY720 in U266 cells. Autophagy induced by FTY720 could lead to cell death. Bafilomycin A1, the inhibitor of autophagy, could enhance the cell viability in U266 cells treated with FTY720. NAC or Tiron, ROS scavenger, could decrease the FTY720 induced apoptosis and the expression of LC3B-II was reduced in combination of FTY720 with NAC or Tiron as compared with treatment with FTY720 only. It is concluded that FTY720 can induce U266 cell apoptosis and autophagy. ROS is the mediator that regulates both the apoptosis and autophagy in multiple myeloma cells.",
        "keywords": [
            "ros",
            "apoptosis",
            "fty720",
            "multiple myeloma",
            "autophagy"
        ],
        "authors": [
            {
                "name": "Ying-Chun Li",
                "org": "* Department of Hematology,Shenjing Hospital,China Medical University,Shenyang ,Liaoning Province,China"
            },
            {
                "name": "Zhuo-Gang Liu",
                "org": "* Department of Hematology,Shenjing Hospital,China Medical University,Shenyang ,Liaoning Province,China"
            },
            {
                "name": "Kun Yao",
                "org": "* Department of Hematology,Shenjing Hospital,China Medical University,Shenyang ,Liaoning Province,China"
            },
            {
                "name": "Hui-Han Wang",
                "org": "* Department of Hematology,Shenjing Hospital,China Medical University,Shenyang ,Liaoning Province,China"
            },
            {
                "name": "Rong Hu",
                "org": "* Department of Hematology,Shenjing Hospital,China Medical University,Shenyang ,Liaoning Province,China"
            },
            {
                "name": "Wei Yang",
                "org": "* Department of Hematology,Shenjing Hospital,China Medical University,Shenyang ,Liaoning Province,China"
            },
            {
                "name": "Ai-Jun Liao",
                "org": "* Department of Hematology,Shenjing Hospital,China Medical University,Shenyang ,Liaoning Province,China"
            }
        ],
        "venue": "Zhongguo shi yan xue ye xue za zhi / Zhongguo bing li sheng li xue hui = Journal of experimental hematology / Chinese Association of Pathophysiology",
        "year": 2013
    },
    "SENhSqIa": {
        "id": "SENhSqIa",
        "title": "Effect of valproic acid sodium on proliferation and apoptosis of acute T-lymphoblastic leukemia Jurkat cells]",
        "abstract": "This study was aimed to investigate the effects of valproic acid sodium (VPA) on the proliferation and apoptosis of acute T-lymphoblastic leukemia Jurkat cells. Jurkat cells were treated with different concentration of VPA. Proliferation-inhibition curve was assayed and plotted by CCK-8 method and the cell apoptosis was detected by flow cytometry with Annexin V/PI double staining. The expression level of anti-apoptotic gene BCL-2 and pro-apoptosis gene Bak1 were detected by semi-quantitative RT-PCR. The results showed that the VPA inhibited the proliferation of Jurkat cells in concentration-dependent manner. As compared with the control group, the apoptosis of cells increased along with adding concentration of VPA; VPA could decrease the expression of BCL-2 gene, but did not show obvious effect on the expression of Bak1. It is concluded that the VPA can inhibit proliferation of Jurkat cells which possibly associates with the decrease of BCL-2 expression.",
        "keywords": [
            "apoptosis",
            "leukemia",
            "vpa",
            "jurkat cell"
        ],
        "authors": [
            {
                "name": "Miao Miao",
                "org": ""
            },
            {
                "name": "Bing Du",
                "org": ""
            },
            {
                "name": "Rong Hu",
                "org": ""
            },
            {
                "name": "Ying Yang",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Ai-Jun Liao",
                "org": ""
            },
            {
                "name": "Zhuo-Gang Liu",
                "org": ""
            }
        ],
        "venue": "Zhongguo shi yan xue ye xue za zhi / Zhongguo bing li sheng li xue hui = Journal of experimental hematology / Chinese Association of Pathophysiology",
        "year": 2013
    },
    "Go2PPylY": {
        "id": "Go2PPylY",
        "title": "Influence of TIEG1 on apoptosis of HL-60 cells and expression of Bcl-2/Bax]",
        "abstract": "This study was aimed to investigate the influence of TIEG1 on apoptosis of HL-60 cells and the expression of Bcl-2/Bax. Different concentration of TIEG1 were used to treat HL-60 cells, the cell growth inhibition rate was detected by MTT method. After treating HL-60 cells with 12.03 ng/ml TIEG1, cell apoptosis was detected with flow cytometry. Bcl-2 and Bax was detected with RT-PCR. The results showed that TIEG1 had inhibitory effect on HL-60 cell proliferation, and in time-and dose-dependent manners. The more obvious inhibitory effect was observed in HL-60 cells treated with TIEG1 of 12.03 ng/ml. During the course of cell apoptosis, Bax expression increased, but Bcl-2 expression decreased (P < 0.05). It is concluded that TIEG1 inhibits HL-60 cell proliferation and induces apoptosis in time and dose-dependent manners. During the course of HL-60 cells apoptosis induced by TIEG1, Bcl-2/Bax are associated with HL-60 cell apoptosis induced by TIEG1.",
        "keywords": [
            "Bcl-2/Bax",
            "HL-60 cell",
            "apoptosis",
            "TIEG1"
        ],
        "authors": [
            {
                "name": "Kun Yao",
                "org": "Department of Hematology, China Medical University, Shengyang, China."
            },
            {
                "name": "Ying Yang",
                "org": "* Department of Hematology,China Medical University Shengjing Hospital,Shengyang ,Liaoning Province,China"
            },
            {
                "name": "Rong Hu",
                "org": "* Department of Hematology,China Medical University Shengjing Hospital,Shengyang ,Liaoning Province,China"
            },
            {
                "name": "Miao Miao",
                "org": "* Department of Hematology,China Medical University Shengjing Hospital,Shengyang ,Liaoning Province,China"
            },
            {
                "name": "Ai-Jun Liao",
                "org": "* Department of Hematology,China Medical University Shengjing Hospital,Shengyang ,Liaoning Province,China"
            },
            {
                "name": "Wei Yang",
                "org": "* Department of Hematology,China Medical University Shengjing Hospital,Shengyang ,Liaoning Province,China"
            },
            {
                "name": "Zhuo-Gang Liu",
                "org": "* Department of Hematology,China Medical University Shengjing Hospital,Shengyang ,Liaoning Province,China"
            }
        ],
        "venue": "Zhongguo shi yan xue ye xue za zhi / Zhongguo bing li sheng li xue hui = Journal of experimental hematology / Chinese Association of Pathophysiology",
        "year": 2013
    },
    "baFpdAA7": {
        "id": "baFpdAA7",
        "title": "Serum adiponectin,leptin,and resistin levels in non-Hodgkin lymphoma patients",
        "abstract": "Objective:To investigate adiponectin,leptin,and resistin levels in patients with non-Hodgkin lymphoma(NHL)at diagnosis and during chemotherapy. Method:ABC-ELLSA was used to detect the adiponectin,leptin,and resistin levels in 45 NHL patients and 50 normal controls.The corresponding lactate dehydrogenase(LDH) levels were also recorded. Result:At diagnosis,mean adiponectin levels were lower compared with controls(P<0.01),and the levels of leptin and resistin were higher(P<0.01).During the chemotherapy,adiponectin increased significantly(P<0.01),while leptin and resistin decreased(P<0.05).The levels of adiponectin were negatively correlated with LDH during the therapy(r=-0.635,P=0.003),while leptin and resistin positively correlated(r=0.532,P=0.025 and r=0.637,P=0.012,respectively). Conclusion:Low adiponectin and high leptin,resistin are present at NHL diagnosis.Those adipocytokines alterations are progressively restored during the therapy.",
        "keywords": [
            "resistin",
            "leptin",
            "adiponectin",
            "non-Hodgkin lymphoma"
        ],
        "authors": [
            {
                "name": "ZHANG Ying",
                "org": "Department of Haematology,the People's Hospital of Liaoning Province,Shenyang,,China"
            },
            {
                "name": "YANG Wei",
                "org": "Department of Haematology,Shengjing Hospital of China Medical University"
            },
            {
                "name": "LIU Dongmei",
                "org": "Department of Haematology,the People's Hospital of Liaoning Province,Shenyang,,China"
            }
        ],
        "venue": "Journal of Clinical Hematology",
        "year": 2013
    },
    "s5469ng4": {
        "id": "s5469ng4",
        "title": "A Meta-analysis on weekly bortezomib schedule for multiple myeloma",
        "abstract": "Objective:To evaluate the curative effect and adverse effect of weekly bortezomib schedule and standard twice-weekly schedule for patients with multiple myeloma.Methods: We used the systematic review method of The Cochrane Collaboration to collect randomized controlled trials(RCTs) of weekly bortezomib chemotherapy for multiple myeloma.Results: Five trials involving 876 patients were retrieved,The overall responsed rate between the treatment group and the control group was no statistically significance;The incidence of peripheral neuropathy in the treatment group was lower.Conclusion: Multiple myeloma treated by weekly bortezomib schedule can produce a similar therapeutic effect as twice-weekly schedule,and reduce the adverse effects.But the included studies were low sample size,and low quality,more high-quality,large-sample size,randomized,double-blind,controlled trials are required.",
        "keywords": [
            "meta-analysis",
            "weekly schedule",
            "multiple myeloma",
            "bortezomib"
        ],
        "authors": [
            {
                "name": "Yan Wei",
                "org": " Department of Hematology,Affiliated Shengjing Hospital of China Medical University,Liaoning Shenyang ,China"
            },
            {
                "name": "Hu Wenxu",
                "org": " Department of Hematology,Affiliated Shengjing Hospital of China Medical University,Liaoning Shenyang ,China"
            },
            {
                "name": "Yang Wei",
                "org": " Department of Hematology,Affiliated Shengjing Hospital of China Medical University,Liaoning Shenyang ,China"
            }
        ],
        "venue": "Journal of Modern Oncology",
        "year": 2013
    },
    "fovrRMfa": {
        "id": "fovrRMfa",
        "title": "Clinical effect of HAG regimen to treat the intermediate and high-risk myelodysplastic syndrome",
        "abstract": "Objective:To observe the efficacy of HAG regimen combined with homoharringtonine,low-dose cytarabine and granulocyte colony-stimulating factor on patients of intermediate and high-risk myelodysplastic syndrome.Methods:The clinical data of 16 new-diagnosed MDS cases treated with HAG regimen and 12 MDS cases treated with CAG regimen in our hospital from 2008 Jan to 2012 Feb were retrospectively analyzed.Results:The efficiency rate of HAG regimen was 87.50%(14 /16),CR rate 56.25%(9 /16).The efficiency rate of CAG regimen was 91.67%(11 /12) while the CR rate was 50%(6 /12).The CR rate and RR rate between HAG and CAG regimen didn 't have statistically significant differences(P > 0.05).Conclusion:With acceptable adverse effect,HAG regimen is effective for the intermediate and high-risk myelodysplastic syndrome,but strong and alternative chemotherapy is necessary for CR patients to keep longer CR and survival.",
        "keywords": [
            "myelodysplastic syndromes",
            "cytarabine",
            "HAG",
            "G-CSF",
            "homoharringtonine"
        ],
        "authors": [
            {
                "name": "Li Yang",
                "org": " Department of Hematology,Shengjing Hospital,China Medical University,Liaoning Shenyang ,China."
            },
            {
                "name": "Li Yingchun",
                "org": " Department of Hematology,Shengjing Hospital,China Medical University,Liaoning Shenyang ,China."
            },
            {
                "name": "Wu Bin",
                "org": " Department of Hematology,Shengjing Hospital,China Medical University,Liaoning Shenyang ,China."
            },
            {
                "name": "Zhang Rong",
                "org": " Department of Hematology,Shengjing Hospital,China Medical University,Liaoning Shenyang ,China."
            },
            {
                "name": "Wang Huihan",
                "org": " Department of Hematology,Shengjing Hospital,China Medical University,Liaoning Shenyang ,China."
            },
            {
                "name": "Yao Kun",
                "org": " Department of Hematology,Shengjing Hospital,China Medical University,Liaoning Shenyang ,China."
            },
            {
                "name": "Liao Aijun",
                "org": " Department of Hematology,Shengjing Hospital,China Medical University,Liaoning Shenyang ,China."
            },
            {
                "name": "Yang Wei",
                "org": " Department of Hematology,Shengjing Hospital,China Medical University,Liaoning Shenyang ,China."
            },
            {
                "name": "Liu Zhuogang",
                "org": " Department of Hematology,Shengjing Hospital,China Medical University,Liaoning Shenyang ,China."
            }
        ],
        "venue": "Journal of Modern Oncology",
        "year": 2013
    },
    "TxUmeb6b": {
        "id": "TxUmeb6b",
        "title": "Crystal Structure of a Y-Family DNA Polymerase in Action: A Mechanism for Error-Prone",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Lesion-bypass Replication",
                "org": ""
            },
            {
                "name": "Hong Ling",
                "org": "Laboratory of Molecular Biology, National Institute of Diabetes and Digestive"
            },
            {
                "name": "Franc Ois Boudsocq",
                "org": "the prototype of each branch of the family, proteins , Section on DNA Replication, Repair,Y-family of DNA polymerases (Ohmori et al., 2001). The National Institute of Child Health"
            },
            {
                "name": "Roger Woodgate",
                "org": "the prototype of each branch of the family, proteins , Section on DNA Replication, Repair,Y-family of DNA polymerases (Ohmori et al., 2001). The National Institute of Child Health"
            },
            {
                "name": "Wei Yang",
                "org": "Laboratory of Molecular Biology, National Institute of Diabetes and Digestive"
            },
            {
                "name": "Kidney Diseases",
                "org": ""
            }
        ],
        "venue": "",
        "year": 0
    },
    "GdqG6Mb9": {
        "id": "GdqG6Mb9",
        "title": "and Substrate Specificity",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Wei Yang",
                "org": "Laboratory of Molecular Biology|National Institute of Diabetes and Digestive and Kidney Diseases|National Institutes of Health Bethesda"
            },
            {
                "name": "Jae Young Lee",
                "org": "Laboratory of Molecular Biology|National Institute of Diabetes and Digestive and Kidney Diseases|National Institutes of Health Bethesda"
            },
            {
                "name": "Marcin Nowotny",
                "org": "Laboratory of Molecular Biology|National Institute of Diabetes and Digestive and Kidney Diseases|National Institutes of Health Bethesda"
            }
        ],
        "venue": "",
        "year": 0
    },
    "nT1EdOzl": {
        "id": "nT1EdOzl",
        "title": "Crystal structure and ATPase activity of MutL: implications for DNA repair and mutagenesis.",
        "abstract": "MutL and its homologs are essential for DNA mismatch repair. Mutations in genes encoding human homologs of MutL cause multiorgan cancer susceptibility. We have determined the crystal structure of a 40 kDa N-terminal fragment of E. coli MutL that retains all of the conserved residues in the MutL family. The structure of MutL is homologous to that of an ATPase-containing fragment of DNA gyrase. We have demonstrated that MutL binds and hydrolyzes ATP to ADP and Pi. Mutations in the MutL family that cause deficiencies in DNA mismatch repair and a predisposition to cancer mainly occur in the putative ATP-binding site. We provide evidence that the flexible, yet conserved, loops surrounding this ATP-binding site undergo conformational changes upon ATP hydrolysis thereby modulating interactions between MutL and other components of the repair machinery.",
        "keywords": [],
        "authors": [
            {
                "name": "C Ban",
                "org": ""
            },
            {
                "name": "W Yang",
                "org": ""
            }
        ],
        "venue": "Cell",
        "year": 1998
    },
    "u5ViBWGM": {
        "id": "u5ViBWGM",
        "title": "Crystal Structure and ATPase Activity of MutL",
        "abstract": "MutL and its homologs are essential for DNA mismatch repair. Mutations in genes encoding human homologs of MutL cause multiorgan cancer susceptibility. We have determined the crystal structure of a 40 kDa N-terminal fragment of E. coli MutL that retains all of the conserved residues in the MutL family. The structure of MutL is homologous to that of an ATPase-containing fragment of DNA gyrase. We have demonstrated that MutL binds and hydrolyzes ATP to ADP and Pi. Mutations in the MutL family that cause deficiencies in DNA mismatch repair and a predisposition to cancer mainly occur in the putative ATP-binding site. We provide evidence that the flexible, yet conserved, loops surrounding this ATP-binding site undergo conformational changes upon ATP hydrolysis thereby modulating interactions between MutL and other components of the repair machinery.",
        "keywords": [
            "binding site",
            "crystal structure",
            "mismatch repair",
            "n terminal",
            "dna gyrase"
        ],
        "authors": [
            {
                "name": "Changill Ban",
                "org": "Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA"
            },
            {
                "name": "Wei Yang",
                "org": ""
            }
        ],
        "venue": "Cell",
        "year": 1998
    },
    "5u2gCzbA": {
        "id": "5u2gCzbA",
        "title": "Structural basis for MutH activation in E.coli mismatch repair and relationship of MutH to restriction endonucleases.",
        "abstract": "MutS, MutL and MutH are the three essential proteins for initiation of methyl-directed DNA mismatch repair to correct mistakes made during DNA replication in Escherichia coli. MutH cleaves a newly synthesized and unmethylated daughter strand 5' to the sequence d(GATC) in a hemi-methylated duplex. Activation of MutH requires the recognition of a DNA mismatch by MutS and MutL. We have crystallized MutH in two space groups and solved the structures at 1.7 and 2.3 A resolution, respectively. The active site of MutH is located at an interface between two subdomains that pivot relative to one another, as revealed by comparison of the crystal structures, and this presumably regulates the nuclease activity. The relative motion of the two subdomains in MutH correlates with the position of a protruding C-terminal helix. This helix appears to act as a molecular lever through which MutS and MutL may communicate the detection of a DNA mismatch and activate MutH. With sequence homology to Sau3AI and structural similarity to PvuII endonuclease, MutH is clearly related to these enzymes by divergent evolution, and this suggests that type II restriction endonucleases evolved from a common ancestor.",
        "keywords": [
            "activation/dna repair/evolution/muth structures/restriction enzymes",
            "mismatch repair",
            "dna repair enzymes",
            "dna repair",
            "restriction enzymes",
            "amino acid sequence",
            "escherichia coli",
            "dna binding proteins",
            "protein conformation",
            "evolution",
            "restriction endonuclease",
            "dna",
            "binding sites",
            "restriction enzyme",
            "enzyme activation"
        ],
        "authors": [
            {
                "name": "C Ban",
                "org": "Laboratory of Molecular Biology|National Institute of Diabetes and Digestive and Kidney Diseases|National Institutes of Health"
            },
            {
                "name": "W Yang",
                "org": "Laboratory of Molecular Biology|National Institute of Diabetes and Digestive and Kidney Diseases|National Institutes of Health"
            }
        ],
        "venue": "The EMBO journal",
        "year": 1998
    },
    "10blv6U8": {
        "id": "10blv6U8",
        "title": "Transformation of MutL by ATP binding and hydrolysis: a switch in DNA mismatch repair.",
        "abstract": "The MutL DNA mismatch repair protein has recently been shown to be an ATPase and to belong to an emerging ATPase superfamily that includes DNA topoisomerase II and Hsp90. We report here the crystal structures of a 40 kDa ATPase fragment of E. coli MutL (LN40) complexed with a substrate analog, ADPnP, and with product ADP. More than 60 residues that are disordered in the apoprotein structure become ordered and contribute to both ADPnP binding and dimerization of LN40. Hydrolysis of ATP, signified by subsequent release of the gamma-phosphate, releases two key loops and leads to dissociation of the LN40 dimer. Dimerization of the LN40 region is required for and is the rate-limiting step in ATP hydrolysis by MutL. The ATPase activity of MutL is stimulated by DNA and likely acts as a switch to coordinate DNA mismatch repair.",
        "keywords": [
            "dna mismatch repair"
        ],
        "authors": [
            {
                "name": "Changill Ban",
                "org": "Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA."
            },
            {
                "name": "Murray Junop",
                "org": "Laboratory of Molecular Biology|National Institute of Diabetes and Digestive"
            },
            {
                "name": "Wei Yang",
                "org": "Laboratory of Molecular Biology|National Institute of Diabetes and Digestive"
            }
        ],
        "venue": "Cell",
        "year": 1999
    },
    "61CDKiem": {
        "id": "61CDKiem",
        "title": "Oligomerization of a MutS mismatch repair protein from Thermus aquaticus.",
        "abstract": "The MutS DNA mismatch protein recognizes heteroduplex DNAs containing mispaired or unpaired bases. We have examined the oligomerization of a MutS protein from Thermus aquaticus that binds to heteroduplex DNAs at elevated temperatures. Analytical gel filtration, cross-linking of MutS protein with disuccinimidyl suberate, light scattering, and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry establish that the Taq protein is largely a dimer in free solution. Analytical equilibrium sedimentation showed that the oligomerization of Taq MutS involves a dimer-tetramer equilibrium in which dimer predominates at concentrations below 10 microM. The DeltaG(0)(2-4) for the dimer to tetramer transition is approximately -6.9 +/- 0.1 kcal/mol of tetramer. Analytical gel filtration of native complexes and gel mobility shift assays of an maltose-binding protein-MutS fusion protein bound to a short, 37-base pair heteroduplex DNA reveal that the protein binds to DNA as a dimer with no change in oligomerization upon DNA binding.",
        "keywords": [
            "light scattering",
            "fusion protein",
            "protein binding",
            "base pair",
            "time of flight mass spectrometry",
            "mismatch repair"
        ],
        "authors": [
            {
                "name": "I Biswas",
                "org": ""
            },
            {
                "name": "C Ban",
                "org": ""
            },
            {
                "name": "K G Fleming",
                "org": ""
            },
            {
                "name": "J Qin",
                "org": ""
            },
            {
                "name": "J W Lary",
                "org": ""
            },
            {
                "name": "D A Yphantis",
                "org": ""
            },
            {
                "name": "W Yang",
                "org": ""
            },
            {
                "name": "P Hsieh",
                "org": ""
            }
        ],
        "venue": "The Journal of biological chemistry",
        "year": 1999
    },
    "gN1YeIVV": {
        "id": "gN1YeIVV",
        "title": "Transformation of MutL by ATP Binding and Hydrolysis",
        "abstract": "The MutL DNA mismatch repair protein has recently been shown to be an ATPase and to belong to an emerging ATPase superfamily that includes DNA topoisomerase II and Hsp90. We report here the crystal structures of a 40 kDa ATPase fragment of E. coli MutL (LN40) complexed with a substrate analog, ADPnP, and with product ADP. More than 60 residues that are disordered in the apoprotein structure become ordered and contribute to both ADPnP binding and dimerization of LN40. Hydrolysis of ATP, signified by subsequent release of the γ-phosphate, releases two key loops and leads to dissociation of the LN40 dimer. Dimerization of the LN40 region is required for and is the rate-limiting step in ATP hydrolysis by MutL. The ATPase activity of MutL is stimulated by DNA and likely acts as a switch to coordinate DNA mismatch repair.",
        "keywords": [
            "mismatch repair",
            "rate limiting",
            "crystal structure"
        ],
        "authors": [
            {
                "name": "Changill Ban",
                "org": "Laboratory of Molecular Biology, National Institute of Diabetes and Digestive, and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA"
            },
            {
                "name": "Murray Junop",
                "org": "Laboratory of Molecular Biology, National Institute of Diabetes and Digestive, and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA"
            },
            {
                "name": "Wei Yang",
                "org": ""
            }
        ],
        "venue": "Cell",
        "year": 1999
    },
    "r5khtRLN": {
        "id": "r5khtRLN",
        "title": "Crystal structures of mismatch repair protein MutS and its complex with a substrate DNA.",
        "abstract": "DNA mismatch repair is critical for increasing replication fidelity in organisms ranging from bacteria to humans. MutS protein, a member of the ABC ATPase superfamily, recognizes mispaired and unpaired bases in duplex DNA and initiates mismatch repair. Mutations in human MutS genes cause a predisposition to hereditary nonpolyposis colorectal cancer as well as sporadic tumours. Here we report the crystal structures of a MutS protein and a complex of MutS with a heteroduplex DNA containing an unpaired base. The structures reveal the general architecture of members of the MutS family, an induced-fit mechanism of recognition between four domains of a MutS dimer and a heteroduplex kinked at the mismatch, a composite ATPase active site composed of residues from both MutS subunits, and a transmitter region connecting the mismatch-binding and ATPase domains. The crystal structures also provide a molecular framework for understanding hereditary nonpolyposis colorectal cancer mutations and for postulating testable roles of MutS.",
        "keywords": [],
        "authors": [
            {
                "name": "G Obmolova",
                "org": ""
            },
            {
                "name": "C Ban",
                "org": ""
            },
            {
                "name": "P Hsieh",
                "org": ""
            },
            {
                "name": "W Yang",
                "org": ""
            }
        ],
        "venue": "Nature",
        "year": 2000
    },
    "cVLuAhll": {
        "id": "cVLuAhll",
        "title": "Crystal structures of mismatch repair protein MutS and its complex with\na substrate DNA",
        "abstract": "DNA mismatch repair is critical for increasing replication fidelity in organisms ranging from bacteria to humans. MutS protein, a member of the ABC ATPase superfamily, recognizes mispaired and unpaired bases in duplex DNA and initiates mismatch repair. Mutations in human MutS genes cause a predisposition to hereditary nonpolyposis colorectal cancer as well as sporadic tumours. Here we report the crystal structures of a MutS protein and a complex of MutS with a heteroduplex DNA containing an unpaired base. The structures reveal the general architecture of members of the MutS family, an induced-fit mechanism of recognition between four domains of a MutS dimer and a heteroduplex kinked at the mismatch, a composite ATPase active site composed of residues from both MutS subunits, and a transmitter region connecting the mismatch-binding and ATPase domains. The crystal structures also provide a molecular framework for understanding hereditary nonpolyposis colorectal cancer mutations and for postulating testable roles of MutS.",
        "keywords": [
            "Nature",
            " science",
            " science news",
            " biology",
            " physics",
            " genetics",
            " astronomy",
            " astrophysics",
            " quantum physics",
            " evolution",
            " evolutionary biology",
            " geophysics",
            " climate change",
            " earth science",
            " materials science",
            " interdisciplinary science",
            " science policy",
            " medicine",
            " systems biology",
            " genomics",
            " transcriptomics",
            " palaeobiology",
            " ecology",
            " molecular biology",
            " cancer",
            " immunology",
            " pharmacology",
            " development",
            " developmental biology",
            " structural biology",
            " biochemistry",
            " bioinformatics",
            " computational biology",
            " nanotechnology",
            " proteomics",
            " metabolomics",
            " biotechnology",
            " drug discovery",
            " environmental science",
            " life",
            " marine biology",
            " medical research",
            " neuroscience",
            " neurobiology",
            " functional genomics",
            " molecular interactions",
            " RNA",
            " DNA",
            " cell cycle",
            " signal transduction",
            " cell signalling"
        ],
        "authors": [
            {
                "name": "Galina Obmolova",
                "org": "Genetics and Biochemistry Branch and"
            },
            {
                "name": "Changill Ban",
                "org": "Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA"
            },
            {
                "name": "Peggy Hsieh",
                "org": "Present address: Hauptman-Woodward Medical Institute, Buffalo, New York, USA."
            },
            {
                "name": "Wei Yang",
                "org": "Genetics and Biochemistry Branch and"
            }
        ],
        "venue": "Nature",
        "year": 2000
    },
    "SFDrgl6g": {
        "id": "SFDrgl6g",
        "title": "Crystal structures of mismatch repair protein MutS and its complex witha substrate DNA",
        "abstract": "",
        "keywords": [
            "astronomy",
            "earth science",
            "genomics",
            "marine biology",
            "pharmacology",
            "crystal structure",
            "replication dna",
            "dna",
            "biology",
            "developmental biology",
            "metabolomics",
            "biochemistry",
            "medicine",
            "bioinformatics",
            "climate change",
            "neurobiology",
            "functional genomics",
            "nanotechnology",
            "genetics",
            "quantum physics",
            "cell signalling",
            "immunology",
            "computational biology",
            "palaeobiology",
            "molecular biology",
            "active site",
            "systems biology",
            "transcriptomics",
            "ecology",
            "astrophysics",
            "cancer",
            "drug discovery",
            "neuroscience",
            "biotechnology",
            "materials science",
            "signal transduction",
            "evolution",
            "induced fit",
            "medical research",
            "rna",
            "geophysics",
            "evolutionary biology",
            "nature",
            "physics",
            "proteomics",
            "environmental science",
            "structural biology",
            "mismatch repair",
            "cell cycle"
        ],
        "authors": [
            {
                "name": "galina obmolova",
                "org": ""
            },
            {
                "name": "changill ban",
                "org": "laboratory of molecular biology"
            },
            {
                "name": "peggy hsieh",
                "org": ""
            },
            {
                "name": "wei yang",
                "org": "laboratory of molecular biology"
            }
        ],
        "venue": "Nature",
        "year": 2000
    },
    "jfrO7FXw": {
        "id": "jfrO7FXw",
        "title": "Crystal structure of a Y-family DNA polymerase in action: a mechanism for error-prone and lesion-bypass replication.",
        "abstract": "Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4) is a DinB homolog that belongs to the recently described Y-family of DNA polymerases, which are best characterized by their low-fidelity synthesis on undamaged DNA templates and propensity to traverse normally replication-blocking lesions. Crystal structures of Dpo4 in ternary complexes with DNA and an incoming nucleotide, either correct or incorrect, have been solved at 1.7 A and 2.1 A resolution, respectively. Despite a conserved active site and a hand-like configuration similar to all known polymerases, Dpo4 makes limited and nonspecific contacts with the replicating base pair, thus relaxing base selection. Dpo4 is also captured in the crystal translocating two template bases to the active site at once, suggesting a possible mechanism for bypassing thymine dimers.",
        "keywords": [],
        "authors": [
            {
                "name": "Hong Ling",
                "org": "Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA."
            },
            {
                "name": "François Boudsocq",
                "org": ""
            },
            {
                "name": "Roger Woodgate",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            }
        ],
        "venue": "Cell",
        "year": 2001
    },
    "SK6oLjdJ": {
        "id": "SK6oLjdJ",
        "title": "Structure of a two-domain fragment of HIV-1 integrase: implications for domain organization in the intact protein.",
        "abstract": "Retroviral integrase, an essential enzyme for replica- tion of human immunodeficiency virus type-1 (HIV-1) and other retroviruses, contains three structurally dis- tinct domains, an N-terminal domain, the catalytic core and a C-terminal domain. To elucidate their spatial arrangement, we have solved the structure of a fragment of HIV-1 integrase comprising the N-terminal and catalytic core domains. This structure reveals a dimer interface between the N-terminal domains different from that observed for the isolated domain. It also complements the previously deter- mined structure of the C-terminal two domains of HIV-1 integrase; superposition of the conserved cata- lytic core of the two structures results in a plausible full-length integrase dimer. Furthermore, an integrase tetramer formed by crystal lattice contacts bears structural resemblance to a related bacterial transpo- sase, Tn5, and exhibits positively charged channels suitable for DNA binding.",
        "keywords": [
            "crystal structure/hiv-1/integrase/ transposon tn5",
            "integrase",
            "c terminal domain",
            "enzyme",
            "crystal structure",
            "n terminal"
        ],
        "authors": [
            {
                "name": "Jian-Yong Wang",
                "org": "Laboratory of Molecular Biology, NIDDK, National Institutes of Health, 5 Center Drive MSC 0560, Bethesda, MD 20892, USA."
            },
            {
                "name": "Hong Ling",
                "org": "Laboratory of Molecular Biology|National Institutes of Health"
            },
            {
                "name": "Wei Yang",
                "org": "Laboratory of Molecular Biology|National Institutes of Health"
            },
            {
                "name": "Robert Craigie",
                "org": "Laboratory of Molecular Biology|National Institutes of Health"
            }
        ],
        "venue": "The EMBO journal",
        "year": 2001
    },
    "M0N9UNpU": {
        "id": "M0N9UNpU",
        "title": "Crystal Structure of a Y-Family DNA Polymerase in Action",
        "abstract": "Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4) is a DinB homolog that belongs to the recently described Y-family of DNA polymerases, which are best characterized by their low-fidelity synthesis on undamaged DNA templates and propensity to traverse normally replication-blocking lesions. Crystal structures of Dpo4 in ternary complexes with DNA and an incoming nucleotide, either correct or incorrect, have been solved at 1.7 Å and 2.1 Å resolution, respectively. Despite a conserved active site and a hand-like configuration similar to all known polymerases, Dpo4 makes limited and nonspecific contacts with the replicating base pair, thus relaxing base selection. Dpo4 is also captured in the crystal translocating two template bases to the active site at once, suggesting a possible mechanism for bypassing thymine dimers.",
        "keywords": [
            "dna polymerase",
            "active site",
            "crystal structure",
            "nucleotides",
            "base pair"
        ],
        "authors": [
            {
                "name": "Hong Ling",
                "org": "Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892 USA"
            },
            {
                "name": "François Boudsocq",
                "org": "Section on DNA Replication, Repair, and Mutagenesis, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892 USA"
            },
            {
                "name": "Roger Woodgate",
                "org": "Section on DNA Replication, Repair, and Mutagenesis, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892 USA"
            },
            {
                "name": "Wei Yang",
                "org": ""
            }
        ],
        "venue": "Cell",
        "year": 2001
    },
    "q2g8apDd": {
        "id": "q2g8apDd",
        "title": "Disruption of the helix-u-turn-helix motif of MutS protein: loss of subunit dimerization, mismatch binding and ATP hydrolysis11Edited by M. Gottesman",
        "abstract": "The DNA mismatch repair protein, MutS, is a dimeric protein that recognizes mismatched bases and has an intrinsic ATPase activity. Here, a series of Taq MutS proteins having C-terminal truncations in the vicinity of a highly conserved helix-u-turn-helix (HuH) motif are assessed for subunit oligomerization, ATPase activity and DNA mismatch binding. Those proteins containing an intact HuH region are dimers; those without the HuH region are predominantly monomers in solution. Steady-state kinetics of truncated but dimeric MutS proteins reveals only modest decreases in their ATPase activity compared to full-length protein. In contrast, disruption of the HuH region results in a greatly attenuated ATPase activity. In addition, only dimeric MutS proteins are proficient for mismatch binding. Finally, an analysis of the mismatch repair competency of truncated Escherichia coli MutS proteins in a rifampicin mutator assay confirms that the HuH region is critical for in vivo function. These findings indicate that dimerization is critical for both the ATPase and DNA mismatch binding activities of MutS, and corroborate several key features of the MutS structure recently deduced from X-ray crystallographic studies.",
        "keywords": [
            "mismatch repair",
            "disuccinimidyl suberate",
            "MutS",
            "hereditary non-polyposis colon cancer",
            "DNA repair",
            "hereditary non-polyposis colorectal cancer",
            "insertion/deletion",
            "HNPCC",
            "helix-u-turn-helix",
            "HuH",
            "microsatellite instability",
            "DSS",
            "I/D"
        ],
        "authors": [
            {
                "name": "Indranil Biswas",
                "org": ""
            },
            {
                "name": "Galina Obmolova",
                "org": "Genetics and Biochemistry Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda MD 20892, USA"
            },
            {
                "name": "Masayuki Takahashi",
                "org": "Universite de Nantes and CNRS, Nantes, Cedex 3, France"
            },
            {
                "name": "Alison Herr",
                "org": "Genetics and Biochemistry Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda MD 20892, USA"
            },
            {
                "name": "M.Andrew Newman",
                "org": "Genetics and Biochemistry Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda MD 20892, USA"
            },
            {
                "name": "Wei Yang",
                "org": "Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda MD 20892, USA"
            },
            {
                "name": "Peggy Hsieh",
                "org": ""
            }
        ],
        "venue": "Journal of Molecular Biology",
        "year": 2001
    },
    "k0oia858": {
        "id": "k0oia858",
        "title": "A Ku Bridge over Broken DNA",
        "abstract": "The Ku heterodimer is essential for the nonhomologous end-joining pathway of DNA double-strand break repair; it both protects the broken ends and recruits some of the many proteins required to complete repair. The recently determined structure of Ku provides insights into how it can both bind to the DNA ends and allow access by the other proteins required to rejoin them.",
        "keywords": [],
        "authors": [
            {
                "name": "Jessica M Jones",
                "org": "Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 9000 Rockville Pike, Building 5, Room B1-03, Bethesda, MD 20892 USA"
            },
            {
                "name": "Martin Gellert",
                "org": "Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 9000 Rockville Pike, Building 5, Room B1-03, Bethesda, MD 20892 USA"
            },
            {
                "name": "Wei Yang",
                "org": ""
            }
        ],
        "venue": "Structure",
        "year": 2001
    },
    "zieKFxRu": {
        "id": "zieKFxRu",
        "title": "Composite Active Site of an ABC ATPase",
        "abstract": "The MutS protein initiates DNA mismatch repair by recognizing mispaired and unpaired bases embedded in duplex DNA and activating endo- and exonucleases to remove the mismatch. Members of the MutS family also possess a conserved ATPase activity that belongs to the ATP binding cassette (ABC) superfamily. Here we report the crystal structure of a ternary complex of MutS-DNA-ADP and assays of initiation of mismatch repair in conjunction with perturbation of the composite ATPase active site by mutagenesis. These studies indicate that MutS has to bind both ATP and the mismatch DNA simultaneously in order to activate the other mismatch repair proteins. We propose that the MutS ATPase activity plays a proofreading role in DNA mismatch repair, verification of mismatch recognition, and authorization of repair.",
        "keywords": [
            "active site",
            "mismatch repair",
            "crystal structure",
            "atp binding cassette"
        ],
        "authors": [
            {
                "name": "Murray S. Junop",
                "org": "Laboratory of Molecular Biology, National Institute of Diabetes and Digestive, and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA"
            },
            {
                "name": "Galina Obmolova",
                "org": "Genetics and Biochemistry Branch, National Institute of Diabetes and Digestive, and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA"
            },
            {
                "name": "Kelly Rausch",
                "org": "Laboratory of Molecular Biology, National Institute of Diabetes and Digestive, and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA"
            },
            {
                "name": "Peggy Hsieh",
                "org": "Genetics and Biochemistry Branch, National Institute of Diabetes and Digestive, and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA"
            },
            {
                "name": "Wei Yang",
                "org": ""
            }
        ],
        "venue": "Molecular Cell",
        "year": 2001
    },
    "7d0WxhHl": {
        "id": "7d0WxhHl",
        "title": "Disruption of the helix-u-turn-helix motif of MutS protein: loss of subunit dimerization, mismatch binding and ATP hydrolysis 1 1 Edited by M. Gottesman",
        "abstract": "",
        "keywords": [
            "steady state",
            "kinetics",
            "escherichia coli",
            "colorectal cancer",
            "mismatch repair"
        ],
        "authors": [
            {
                "name": "indranil biswas",
                "org": "national institute of diabetes and digestive and kidney diseases"
            },
            {
                "name": "galina obmolova",
                "org": "national institute of diabetes and digestive and kidney diseases"
            },
            {
                "name": "masayuki takahashi",
                "org": "university of nantes"
            },
            {
                "name": "alison m herr",
                "org": "national institute of diabetes and digestive and kidney diseases"
            },
            {
                "name": "m andrew newman",
                "org": "national institute of diabetes and digestive and kidney diseases"
            },
            {
                "name": "wei yang",
                "org": "laboratory of molecular biology"
            },
            {
                "name": "peggy hsieh",
                "org": "national institute of diabetes and digestive and kidney diseases"
            }
        ],
        "venue": "Journal of Molecular Biology",
        "year": 2001
    },
    "Awf6x63J": {
        "id": "Awf6x63J",
        "title": "Composite active site of an ABC ATPase: MutS uses ATP to verify mismatch recognition and authorize DNA repair.",
        "abstract": "The MutS protein initiates DNA mismatch repair by recognizing mispaired and unpaired bases embedded in duplex DNA and activating endo- and exonucleases to remove the mismatch. Members of the MutS family also possess a conserved ATPase activity that belongs to the ATP binding cassette (ABC) superfamily. Here we report the crystal structure of a ternary complex of MutS-DNA-ADP and assays of initiation of mismatch repair in conjunction with perturbation of the composite ATPase active site by mutagenesis. These studies indicate that MutS has to bind both ATP and the mismatch DNA simultaneously in order to activate the other mismatch repair proteins. We propose that the MutS ATPase activity plays a proofreading role in DNA mismatch repair, verification of mismatch recognition, and authorization of repair.",
        "keywords": [],
        "authors": [
            {
                "name": "Murray S. Junop",
                "org": "Laboratory of Molecular Biology, National Institute of Diabetes and Digestive, and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA."
            },
            {
                "name": "Galina Obmolova",
                "org": ""
            },
            {
                "name": "Kelly Rausch",
                "org": ""
            },
            {
                "name": "Peggy Hsieh",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            }
        ],
        "venue": "Molecular cell",
        "year": 2001
    },
    "cw1p3wZU": {
        "id": "cw1p3wZU",
        "title": "Structure and function of the N-terminal 40 kDa fragment of human PMS2: a monomeric GHL ATPase.",
        "abstract": "Human MutLalpha, a heterodimer of hMLH1 and hPMS2, is essential for DNA mismatch repair. Inactivation of the hmlh1 or hpms2 genes by mutation or epigenesis causes genomic instability and a predisposition to hereditary non-polyposis cancer. We report here the X-ray crystal structures of the conserved N-terminal 40 kDa fragment of hPMS2, NhPMS2, and its complexes with ATPgammaS and ADP at 1.95, 2.7 and 2.7 A resolution, respectively. The NhPMS2 structures closely resemble the ATPase fragment of Escherichia coli MutL, which coordinates protein-protein interactions in mismatch repair by undergoing structural transformation upon binding of ATP. Unlike the E.coli MutL, whose ATPase activity requires protein dimerization, the monomeric form of NhPMS2 is active both in ATP hydrolysis and DNA binding. NhPMS2 is the first example of a GHL ATPase active as a monomer, suggesting that its activity may be modulated by hMLH1 in MutLalpha, and vice versa. The potential heterodimer interface revealed by crystallography provides a mutagenesis target for functional studies of MutLalpha.",
        "keywords": [
            "dna binding/ghl atpase/hnpcc/ mismatch repair/pms2",
            "dna repair",
            "amino acid sequence",
            "binding sites",
            "dna binding proteins",
            "carrier proteins",
            "mismatch repair",
            "dna repair enzymes",
            "n terminal"
        ],
        "authors": [
            {
                "name": "A Guarné",
                "org": "Laboratory of Molecular Biology|National Institute of Diabetes and Digestive and Kidney Diseases|National Institutes of Health"
            },
            {
                "name": "M S Junop",
                "org": "Laboratory of Molecular Biology|National Institute of Diabetes and Digestive and Kidney Diseases|National Institutes of Health"
            },
            {
                "name": "W Yang",
                "org": "Laboratory of Molecular Biology|National Institute of Diabetes and Digestive and Kidney Diseases|National Institutes of Health"
            }
        ],
        "venue": "The EMBO journal",
        "year": 2001
    },
    "syd8Ye1V": {
        "id": "syd8Ye1V",
        "title": "Disruption of the helix-u-turn-helix motif of MutS protein: loss of subunit dimerization, mismatch binding and ATP hydrolysis.",
        "abstract": "The DNA mismatch repair protein, MutS, is a dimeric protein that recognizes mismatched bases and has an intrinsic ATPase activity. Here, a series of Taq MutS proteins having C-terminal truncations in the vicinity of a highly conserved helix-u-turn-helix (HuH) motif are assessed for subunit oligomerization, ATPase activity and DNA mismatch binding. Those proteins containing an intact HuH region are dimers; those without the HuH region are predominantly monomers in solution. Steady-state kinetics of truncated but dimeric MutS proteins reveals only modest decreases in their ATPase activity compared to full-length protein. In contrast, disruption of the HuH region results in a greatly attenuated ATPase activity. In addition, only dimeric MutS proteins are proficient for mismatch binding. Finally, an analysis of the mismatch repair competency of truncated Escherichia coli MutS proteins in a rifampicin mutator assay confirms that the HuH region is critical for in vivo function. These findings indicate that dimerization is critical for both the ATPase and DNA mismatch binding activities of MutS, and corroborate several key features of the MutS structure recently deduced from X-ray crystallographic studies.",
        "keywords": [
            "muts",
            "dss",
            "mismatch repair",
            "dna repair"
        ],
        "authors": [
            {
                "name": "I Biswas",
                "org": ""
            },
            {
                "name": "G Obmolova",
                "org": ""
            },
            {
                "name": "M Takahashi",
                "org": ""
            },
            {
                "name": "A Herr",
                "org": ""
            },
            {
                "name": "M A Newman",
                "org": ""
            },
            {
                "name": "W Yang",
                "org": ""
            },
            {
                "name": "P Hsieh",
                "org": ""
            }
        ],
        "venue": "Journal of molecular biology",
        "year": 2001
    },
    "dZdPrkND": {
        "id": "dZdPrkND",
        "title": "Structure-based interpretation of missense mutations in Y-family DNA polymerases and their implications for polymerase function and lesion bypass.",
        "abstract": "Our understanding of the molecular mechanisms of error-prone lesion bypass has changed dramatically in the past few years. The concept that the key participants in the mutagenic process were accessory proteins that somehow modified the ability of the cell's main replicase to facilitate bypass of normally blocking lesions has been replaced with one in which the replicase is displaced by a polymerase specialized in lesion bypass. The participants in this process remain the same, only their function has been reassigned. What was once known as the UmuC/DinB/Rev1/Rad30 superfamily of mutagenesis proteins, is now known as the Y-family of DNA polymerases. Quite remarkably, within the space of 3 years, the field has advanced from the initial discovery of intrinsic polymerase function, to the determination of the tertiary structures of several Y-family DNA polymerases.A key to determining the biochemical properties of each DNA polymerase is through structure-function studies that result in the site-specific substitution of particular amino acids at critical sites within each DNA polymerase. However, we should not forget the power of genetic selection that allows us to identify residues within each polymerase that are generated by \"random mutagenesis\" and which are important for both a gain or loss of function in vivo. In this review, we discuss the structural ramifications of several missense mutations previously identified in various Y-family DNA polymerase and speculate on how each amino acid substitution might modify the enzymatic activity of the respective polymerase or possibly perturb protein-protein interactions necessary for efficient translesion replication in vivo.",
        "keywords": [
            "pol η",
            "rev1",
            "pol iv",
            "pol κ",
            "pol v",
            "dna replication",
            "pol ι",
            "structure function",
            "missense mutation",
            "molecular mechanics",
            "dna polymerase",
            "genetic selection",
            "amino acid",
            "protein protein interaction"
        ],
        "authors": [
            {
                "name": "François Boudsocq",
                "org": "Section on DNA Replication, Repair and Mutagenesis, Building 6, Room 1A13, National Institute of Child Health and Human Development, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD 20892-2725, USA"
            },
            {
                "name": "Hong Ling",
                "org": "Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892-0510, USA"
            },
            {
                "name": "Wei Yang",
                "org": "Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892-0510, USA"
            },
            {
                "name": "Roger Woodgate",
                "org": ""
            }
        ],
        "venue": "DNA repair",
        "year": 2002
    },
    "EYc5Hiy7": {
        "id": "EYc5Hiy7",
        "title": "Evidence for sequential action of two ATPase active sites in yeast Msh2-Msh6.",
        "abstract": "Bacterial MutS homodimers contain two ATPase active sites that have non-equivalent functions in DNA mismatch repair. The homologous Msh2-Msh6 complex in eukaryotes also has intrinsic ATPase activity that is essential for mismatch repair. Here, we investigate differences in the two putative ATPase active sites by examining the properties of heterodimers containing alanine substituted for an invariant glutamic acid in the active site of either Msh2, Msh6 or both. Mutation rates in wild type versus Glu-->Ala mutant haploid yeast strains indicate that both ATPase active sites are essential for mismatch repair activity in vivo. The properties of purified heterodimers suggest that the ATPase active site in Msh6 binds ATP with higher affinity and hydrolyzes ATP faster and with higher efficiency than does the ATPase active site in Msh2. This suggests sequential action of the two ATPase active sites, in which ATP binds to Msh6 first to trigger downstream events in mismatch repair.",
        "keywords": [
            "msh6",
            "msh2",
            "walker b",
            "muts",
            "atp hydrolysis",
            "wild type",
            "mutation rate",
            "mismatch repair",
            "active site"
        ],
        "authors": [
            {
                "name": "Karin Drotschmann",
                "org": "Laboratory of Molecular Genetics, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA"
            },
            {
                "name": "Wei Yang",
                "org": "Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institute of Health, Bethesda, MD 20892, USA"
            },
            {
                "name": "Thomas A Kunkel",
                "org": ""
            }
        ],
        "venue": "DNA repair",
        "year": 2002
    },
    "Cv1xECkr": {
        "id": "Cv1xECkr",
        "title": "Replication of a cis|[ndash]|syn thymine dimer at atomic resolution",
        "abstract": "Ultraviolet light damages DNA by catalysing covalent bond formation between adjacent pyrimidines, generating cis–syn cyclobutane pyrimidine dimers (CPDs) as the most common lesion1. CPDs block DNA replication by high-fidelity DNA polymerases, but they can be efficiently bypassed by the Y-family DNA polymerase pol η2, 3. Mutations in POLH encoding pol η are implicated in nearly 20% of xeroderma pigmentosum, a human disease characterized by extreme sensitivity to sunlight and predisposition to skin cancer4, 5, 6. Here we have determined two crystal structures of Dpo4, an archaeal pol η homologue, complexed with CPD-containing DNA, where the 3′ and 5′ thymine of the CPD separately serves as a templating base. The 3′ thymine of the CPD forms a Watson–Crick base pair with the incoming dideoxyATP, but the 5′ thymine forms a Hoogsteen base pair with the dideoxyATP in syn conformation. Dpo4 retains a similar tertiary structure, but each unusual DNA structure is individually fitted into the active site for catalysis. A model of the pol η–CPD complex built from the crystal structures of Saccharomyces cerevisiae apo-pol η and the Dpo4–CPD complex suggests unique features that allow pol η to efficiently bypass CPDs.",
        "keywords": [
            "Nature",
            " science",
            " science news",
            " biology",
            " physics",
            " genetics",
            " astronomy",
            " astrophysics",
            " quantum physics",
            " evolution",
            " evolutionary biology",
            " geophysics",
            " climate change",
            " earth science",
            " materials science",
            " interdisciplinary science",
            " science policy",
            " medicine",
            " systems biology",
            " genomics",
            " transcriptomics",
            " palaeobiology",
            " ecology",
            " molecular biology",
            " cancer",
            " immunology",
            " pharmacology",
            " development",
            " developmental biology",
            " structural biology",
            " biochemistry",
            " bioinformatics",
            " computational biology",
            " nanotechnology",
            " proteomics",
            " metabolomics",
            " biotechnology",
            " drug discovery",
            " environmental science",
            " life",
            " marine biology",
            " medical research",
            " neuroscience",
            " neurobiology",
            " functional genomics",
            " molecular interactions",
            " RNA",
            " DNA",
            " cell cycle",
            " signal transduction",
            " cell signalling"
        ],
        "authors": [
            {
                "name": "Hong Ling",
                "org": "Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, and"
            },
            {
                "name": "François Boudsocq",
                "org": "Laboratory of Genomic Integrity, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA"
            },
            {
                "name": "Brian S. Plosky",
                "org": "Present address: Institut de Pharmacologie et de Biologie Structurale, CNRS, 31077 Toulouse, France"
            },
            {
                "name": "Roger Woodgate",
                "org": "Laboratory of Genomic Integrity, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA"
            },
            {
                "name": "Wei Yang",
                "org": "Laboratory of Genomic Integrity, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA"
            }
        ],
        "venue": "Nature",
        "year": 2003
    },
    "w89adggW": {
        "id": "w89adggW",
        "title": "Tetramerization and DNA ligase IV interaction of the DNA double-strand break repair protein XRCC4 are mutually exclusive.",
        "abstract": "The XRCC4 protein is of critical importance for the repair of broken chromosomal DNA by non-homologous end joining (NHEJ). The absence of XRCC4 abolishes chromosomal NHEJ almost completely. One reason for this severe phenotype is that XRCC4 binds and modulates the stability and activity of the NHEJ-specific ligase, DNA ligase IV. XRCC4 in solution is in equilibrium between the dimeric and tetrameric forms. Previous structural studies have shown that the interface between dimers is located in the same region as that implicated in DNA ligase IV interaction. With the use of equilibrium sedimentation analysis, we show here that only the XRCC4 dimer can associate with DNA ligase IV, forming a monodisperse complex of 2:1 stoichiometry in solution. In addition, physical analysis of XRCC4/DNA ligase IV complex formation, combined with mutational analysis of XRCC4, indicates that tetramerization and DNA ligase IV binding are mutually exclusive. We propose that the putative function of the XRCC4 tetramer is distinct from its DNA ligase IV-associated function.",
        "keywords": [
            "non-homologous end joining",
            "surface plasmon resonance",
            "dsb",
            "v(d)j recombination",
            "glutathione- s -transferase",
            "dna-pkcs",
            "dna repair",
            "dna double-strand break",
            "gst",
            "spr",
            "nhej",
            "catalytic subunit of dna-pk",
            "dna-dependent protein kinase",
            "protein–protein interaction",
            "dna-pk",
            "glutathione",
            "mutation analysis",
            "protein kinase",
            "non homologous end joining",
            "protein protein interaction"
        ],
        "authors": [
            {
                "name": "Mauro Modesti",
                "org": "Department of Cell Biology and Genetics, Erasmus Medical Center, P.O. Box 1738, 3000 DR Rotterdam, The Netherlands"
            },
            {
                "name": "Murray S Junop",
                "org": "Department of Biochemistry, McMaster University, Health Sciences Centre, Rm 4N59, 1200 Main St. West, Hamilton, Canada, L8N 3Z5"
            },
            {
                "name": "Rodolfo Ghirlando",
                "org": "Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA"
            },
            {
                "name": "Mandy van de Rakt",
                "org": "Department of Cell Biology and Genetics, Erasmus Medical Center, P.O. Box 1738, 3000 DR Rotterdam, The Netherlands"
            },
            {
                "name": "Martin Gellert",
                "org": "Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA"
            },
            {
                "name": "Wei Yang",
                "org": "Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA"
            },
            {
                "name": "Roland Kanaar",
                "org": ""
            }
        ],
        "venue": "Journal of molecular biology",
        "year": 2003
    },
    "Dg24v0hm": {
        "id": "Dg24v0hm",
        "title": "Replication of a cis-syn thymine dimer at atomic resolution.",
        "abstract": "Ultraviolet light damages DNA by catalysing covalent bond formation between adjacent pyrimidines, generating cis-syn cyclobutane pyrimidine dimers (CPDs) as the most common lesion. CPDs block DNA replication by high-fidelity DNA polymerases, but they can be efficiently bypassed by the Y-family DNA polymerase pol eta. Mutations in POLH encoding pol eta are implicated in nearly 20% of xeroderma pigmentosum, a human disease characterized by extreme sensitivity to sunlight and predisposition to skin cancer. Here we have determined two crystal structures of Dpo4, an archaeal pol eta homologue, complexed with CPD-containing DNA, where the 3' and 5' thymine of the CPD separately serves as a templating base. The 3' thymine of the CPD forms a Watson-Crick base pair with the incoming dideoxyATP, but the 5' thymine forms a Hoogsteen base pair with the dideoxyATP in syn conformation. Dpo4 retains a similar tertiary structure, but each unusual DNA structure is individually fitted into the active site for catalysis. A model of the pol eta-CPD complex built from the crystal structures of Saccharomyces cerevisiae apo-pol eta and the Dpo4-CPD complex suggests unique features that allow pol eta to efficiently bypass CPDs.",
        "keywords": [],
        "authors": [
            {
                "name": "Hong Ling",
                "org": "Laboratory of Molecular Biology, National Institute of Diabetes and Digestive"
            },
            {
                "name": "François Boudsocq",
                "org": "and Kidney Diseases, and ,Laboratory of Genomic Integrity, National Institute of"
            },
            {
                "name": "Brian S Plosky",
                "org": "and Kidney Diseases, and ,Laboratory of Genomic Integrity, National Institute of"
            },
            {
                "name": "Roger Woodgate",
                "org": "and Kidney Diseases, and ,Laboratory of Genomic Integrity, National Institute of"
            },
            {
                "name": "Wei Yang",
                "org": "Laboratory of Molecular Biology, National Institute of Diabetes and Digestive"
            }
        ],
        "venue": "Nature",
        "year": 2003
    },
    "qyMIgCYC": {
        "id": "qyMIgCYC",
        "title": "Replication of a cis|[ndash]|syn thymine dimer at atomic resolution",
        "abstract": "",
        "keywords": [
            "dna structure",
            "palaeobiology",
            "physics",
            "cancer",
            "medicine",
            "structural biology",
            "cell signalling",
            "computational biology",
            "earth science",
            "molecular biology",
            "base pair",
            "crystal structure",
            "genomics",
            "drug discovery",
            "materials science",
            "quantum physics",
            "astronomy",
            "dna",
            "cell cycle",
            "neuroscience",
            "biotechnology",
            "dna polymerase",
            "geophysics",
            "biology",
            "biochemistry",
            "proteomics",
            "transcriptomics",
            "dna replication",
            "genetics",
            "climate change",
            "functional genomics",
            "environmental science",
            "signal transduction",
            "bioinformatics",
            "evolution",
            "marine biology",
            "systems biology",
            "immunology",
            "neurobiology",
            "medical research",
            "ecology",
            "nanotechnology",
            "nature",
            "pharmacology",
            "developmental biology",
            "evolutionary biology",
            "active site",
            "astrophysics",
            "rna",
            "metabolomics"
        ],
        "authors": [
            {
                "name": "hong ling",
                "org": "laboratory of molecular biology"
            },
            {
                "name": "francois boudsocq",
                "org": "eunice kennedy shriver national institute of child health and human development"
            },
            {
                "name": "brian s plosky",
                "org": "eunice kennedy shriver national institute of child health and human development"
            },
            {
                "name": "roger woodgate",
                "org": "eunice kennedy shriver national institute of child health and human development"
            },
            {
                "name": "wei yang",
                "org": "laboratory of molecular biology"
            }
        ],
        "venue": "Nature",
        "year": 2003
    },
    "ohyWGiWF": {
        "id": "ohyWGiWF",
        "title": "Damage repair DNA polymerases Y.",
        "abstract": "The newly found Y-family DNA polymerases are characterized by low fidelity replication using an undamaged template and the ability to carry out translesion DNA synthesis. The crystal structures of three Y-family polymerases, alone or complexed with DNA and nucleotide substrate, reveal a conventional right-hand-like catalytic core consisting of finger, thumb and palm domains. The finger and thumb domains are unusually small resulting in an open and spacious active site, which can accommodate mismatched base pairs as well as various DNA lesions. Although devoid of a 3'-->5' exonuclease activity, the Y-family polymerases possess a unique \"little finger\" domain that facilitates DNA association, catalytic efficiency and interactions with auxiliary factors. Expression of Y-family polymerases is often induced by DNA damage, and their recruitment to the replication fork is mediated by beta-clamp, clamp loader, single-strand-DNA-binding protein and RecA in Escherichia coli, and by ubiquitin-modified proliferating cell nuclear antigen in yeast.",
        "keywords": [
            "uv",
            "protein data bank",
            "sumo",
            "tls",
            "pcna",
            "pdb",
            "ssb",
            "translesion synthesis",
            "single-strand-dna-binding protein",
            "ultraviolet",
            "proliferating cell nuclear antigen",
            "small ubiquitin-related modifier",
            "dna synthesis",
            "base pair",
            "escherichia coli",
            "crystal structure",
            "dna polymerase",
            "dna damage",
            "dna binding protein",
            "active site",
            "nucleotides"
        ],
        "authors": [
            {
                "name": "Wei Yang",
                "org": "Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA"
            }
        ],
        "venue": "Current opinion in structural biology",
        "year": 2003
    },
    "AKNJUmJ6": {
        "id": "AKNJUmJ6",
        "title": "Investigating the role of the little finger domain of Y-family DNA polymerases in low fidelity synthesis and translesion replication.",
        "abstract": "Dpo4 and Dbh are Y-family polymerases that originate from two closely related strains of Sulfolobaceae. Quite surprisingly, however, the two polymerases exhibit different enzymatic properties in vitro. For example, Dpo4 can replicate past a variety of DNA lesions, yet Dbh does so with a much lower efficiency. When replicating undamaged DNA, Dpo4 is prone to make base pair substitutions, whereas Dbh predominantly makes single-base deletions. Overall, the two proteins are 54% identical, but the greatest divergence is found in their respective little finger (LF) domains, which are only 41% identical. To investigate the role of the LF domain in the fidelity and lesion-bypassing abilities of Y-family polymerases, we have generated chimeras of Dpo4 and Dbh in which their LF domains have been interchanged. Interestingly, by replacing the LF domain of Dbh with that of Dpo4, the enzymatic properties of the chimeric enzyme are more Dpo4-like in that the enzyme is more processive, can bypass an abasic site and a thymine-thymine cyclobutane pyrimidine dimer, and predominantly makes base pair substitutions when replicating undamaged DNA. The converse is true for the Dpo4-LF-Dbh chimera, which is more Dbh-like in its processivity and ability to bypass DNA adducts and generate single-base deletion errors. Our studies indicate that the unique but variable LF domain of Y-family polymerases plays a major role in determining the enzymatic and biological properties of each individual Y-family member.",
        "keywords": [
            "enzyme",
            "base pair",
            "molecular mechanics",
            "dna polymerase",
            "genomic dna"
        ],
        "authors": [
            {
                "name": "François Boudsocq",
                "org": ""
            },
            {
                "name": "Robert J Kokoska",
                "org": ""
            },
            {
                "name": "Brian S Plosky",
                "org": ""
            },
            {
                "name": "Alexandra Vaisman",
                "org": ""
            },
            {
                "name": "Hong Ling",
                "org": ""
            },
            {
                "name": "Thomas A Kunkel",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Roger Woodgate",
                "org": ""
            }
        ],
        "venue": "The Journal of biological chemistry",
        "year": 2004
    },
    "krPWaQLe": {
        "id": "krPWaQLe",
        "title": "Snapshots of Replication through an Abasic Lesion",
        "abstract": "Dpo4 from S. Solfataricus , a DinB-like Y family polymerase, efficiently replicates DNA past an abasic lesion. We have determined crystal structures of Dpo4 complexed with five different abasic site-containing DNA substrates and find that translesion synthesis is template directed with the abasic site looped out and the incoming nucleotide is opposite the base 5′ to the lesion. The ensuing DNA synthesis generates a −1 frameshift when the abasic site remains extrahelical. Template realignment during primer extension is also observed, resulting in base substitutions or even +1 frameshifts. In the case of a +1 frameshift, the extra nucleotide is accommodated in the solvent-exposed minor groove. In addition, the structure of an unproductive Dpo4 ternary complex suggests that the flexible little finger domain facilitates DNA orientation and translocation during translesion synthesis.",
        "keywords": [
            "nucleotides",
            "dna synthesis",
            "crystal structure"
        ],
        "authors": [
            {
                "name": "Hong Ling",
                "org": ""
            },
            {
                "name": "François Boudsocq",
                "org": ""
            },
            {
                "name": "Roger Woodgate",
                "org": "Laboratory of Genomic Integrity, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892 USA"
            },
            {
                "name": "Wei Yang",
                "org": "Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892 USA"
            }
        ],
        "venue": "Molecular Cell",
        "year": 2004
    },
    "YpyUtEeh": {
        "id": "YpyUtEeh",
        "title": "Crystal structure of a benzo[a]pyrene diol epoxide adduct in a ternary complex with a DNA polymerase.",
        "abstract": "The first occupation-associated cancers to be recognized were the sooty warts (cancers of the scrotum) suffered by chimney sweeps in 18th century England. In the 19th century, high incidences of skin cancers were noted among fuel industry workers. By the early 20th century, malignant skin tumors were produced in laboratory animals by repeatedly painting them with coal tar. The culprit in coal tar that induces cancer was finally isolated in 1933 and determined to be benzo[a]pyrene (BP), a polycyclic aromatic hydrocarbon. A residue of fuel and tobacco combustion and frequently ingested by humans, BP is metabolized in mammals to benzo[a]pyrene diol epoxide (BPDE), which forms covalent DNA adducts and induces tumor growth. In the 70 yr since its isolation, BP has been the most studied carcinogen. Yet, there has been no crystal structure of a BPDE DNA adduct. We report here the crystal structure of a BPDE-adenine adduct base-paired with thymine at a template-primer junction and complexed with the lesion-bypass DNA polymerase Dpo4 and an incoming nucleotide. Two conformations of the BPDE, one intercalated between base pairs and another solvent-exposed in the major groove, are observed. The latter conformation, which can be stabilized by organic solvents that reduce the dielectric constant, seems more favorable for DNA replication by Dpo4. These structures also suggest a mechanism by which mutations are generated during replication of DNA containing BPDE adducts.",
        "keywords": [
            "base pairing",
            "binding sites",
            "dielectric constant",
            "protein conformation",
            "dna replication",
            "dna polymerase",
            "crystal structure",
            "base pair",
            "nucleotides"
        ],
        "authors": [
            {
                "name": "Hong Ling",
                "org": ""
            },
            {
                "name": "Jane M Sayer",
                "org": ""
            },
            {
                "name": "Brian S Plosky",
                "org": ""
            },
            {
                "name": "Haruhiko Yagi",
                "org": ""
            },
            {
                "name": "François Boudsocq",
                "org": ""
            },
            {
                "name": "Roger Woodgate",
                "org": ""
            },
            {
                "name": "Donald M Jerina",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            }
        ],
        "venue": "Proceedings of the National Academy of Sciences of the United States of America",
        "year": 2004
    },
    "upLMQymb": {
        "id": "upLMQymb",
        "title": "Snapshots of Replication through an Abasic LesionStructural Basis for Base Substitutions and Frameshifts",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Hong Ling",
                "org": "Laboratory of Molecular Biology, National Institute of Diabetes and Digestive"
            },
            {
                "name": "François Boudsocq",
                "org": "Although sharing no detectable primary amino,acid , Laboratory of Genomic,Integrity"
            },
            {
                "name": "Roger Woodgate",
                "org": "Although sharing no detectable primary amino,acid , Laboratory of Genomic,Integrity"
            },
            {
                "name": "Wei Yang",
                "org": "Laboratory of Molecular Biology, National Institute of Diabetes and Digestive"
            }
        ],
        "venue": "Molecular Cell",
        "year": 2004
    },
    "XvU7R7oz": {
        "id": "XvU7R7oz",
        "title": "Proliferating cell nuclear antigen-dependent coordination of the biological functions of human DNA polymerase iota.",
        "abstract": "Y-family DNA polymerases are believed to facilitate the replicative bypass of damaged DNA in a process commonly referred to as translesion synthesis. With the exception of DNA polymerase eta (poleta), which is defective in humans with the Xeroderma pigmentosum variant (XP-V) phenotype, little is known about the cellular function(s) of the remaining human Y-family DNA polymerases. We report here that an interaction between human DNA polymerase iota (poliota) and the proliferating cell nuclear antigen (PCNA) stimulates the processivity of poliota in a template-dependent manner in vitro. Mutations in one of the putative PCNA-binding motifs (PIP box) of poliota or the interdomain connector loop of PCNA diminish the binding between poliota and PCNA and concomitantly reduce PCNA-dependent stimulation of poliota activity. Furthermore, although retaining its capacity to interact with poleta in vivo, the poliota-PIP box mutant fails to accumulate in replication foci. Thus, PCNA, acting as both a scaffold and a modulator of the different activities involved in replication, appears to recruit and coordinate replicative and translesion DNA synthesis polymerases to ensure genome integrity.",
        "keywords": [
            "proliferating cell nuclear antigen",
            "dna polymerase"
        ],
        "authors": [
            {
                "name": "Antonio E Vidal",
                "org": "Laboratory of Genomic Integrity, NICHD, National Institutes of Health, Bethesda, Maryland 20892-2725, USA."
            },
            {
                "name": "Patricia Kannouche",
                "org": ""
            },
            {
                "name": "Vladimir N Podust",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Alan R Lehmann",
                "org": ""
            },
            {
                "name": "Roger Woodgate",
                "org": ""
            }
        ],
        "venue": "The Journal of biological chemistry",
        "year": 2004
    },
    "qI20Nq2t": {
        "id": "qI20Nq2t",
        "title": "Fidelity of Dpo4: effect of metal ions, nucleotide selection and pyrophosphorolysis.",
        "abstract": "We report the crystal structures of a translesion DNA polymerase, Dpo4, complexed with a matched or mismatched incoming nucleotide and with a pyrophosphate product after misincorporation. These structures suggest two mechanisms by which Dpo4 may reject a wrong incoming nucleotide with its preformed and open active site. First, a mismatched replicating base pair leads to poor base stacking and alignment of the metal ions and as a consequence, inhibits incorporation. By replacing Mg2+ with Mn2+, which has a relaxed coordination requirement and tolerates misalignment, the catalytic efficiency of misincorporation increases dramatically. Mn2+ also enhances translesion synthesis by Dpo4. Subtle conformational changes that lead to the proper metal ion coordination may, therefore, be a key step in catalysis. Second, the slow release of pyrophosphate may increase the fidelity of Dpo4 by stalling mispaired primer extension and promoting pyrophosphorolysis that reverses the polymerization reaction. Indeed, Dpo4 has robust pyrophosphorolysis activity and degrades the primer strand in the presence of pyrophosphate. The correct incoming nucleotide allows DNA synthesis to overcome pyrophosphorolysis, but an incorrect incoming nucleotide does not.",
        "keywords": [
            "mismatch",
            "fidelity",
            "pyrophosphorolysis",
            "base stacking",
            "metal ion",
            "manganese",
            "protein conformation",
            "catalysis",
            "nucleotides",
            "binding sites",
            "kinetics",
            "magnesium"
        ],
        "authors": [
            {
                "name": "Alexandra Vaisman",
                "org": ""
            },
            {
                "name": "Hong Ling",
                "org": ""
            },
            {
                "name": "Roger Woodgate",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            }
        ],
        "venue": "The EMBO journal",
        "year": 2005
    },
    "XJOHLm9I": {
        "id": "XJOHLm9I",
        "title": "UvrD Helicase Unwinds DNA One Base Pair at a Time by a Two-Part Power Stroke",
        "abstract": "Helicases use the energy derived from nucleoside triphosphate hydrolysis to unwind double helices in essentially every metabolic pathway involving nucleic acids. Earlier crystal structures have suggested that DNA helicases translocate along a single-stranded DNA in an inchworm fashion. We report here a series of crystal structures of the UvrD helicase complexed with DNA and ATP hydrolysis intermediates. These structures reveal that ATP binding alone leads to unwinding of 1 base pair by directional rotation and translation of the DNA duplex, and ADP and Pi release leads to translocation of the developing single strand. Thus DNA unwinding is achieved by a two-part power stroke in a combined wrench-and-inchworm mechanism. The rotational angle and translational distance of DNA define the unwinding step to be 1 base pair per ATP hydrolyzed. Finally, a gateway for ssDNA translocation and an alternative strand-displacement mode may explain the varying step sizes reported previously.",
        "keywords": [
            "base pair"
        ],
        "authors": [
            {
                "name": "Jae Young Lee",
                "org": "Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA"
            },
            {
                "name": "Wei Yang",
                "org": ""
            }
        ],
        "venue": "Cell",
        "year": 2006
    },
    "7IhAwZBe": {
        "id": "7IhAwZBe",
        "title": "Mechanism of Template-independent Nucleotide Incorporation Catalyzed by a Template-dependent DNA Polymerase",
        "abstract": "Numerous template-dependent DNA polymerases are capable of catalyzing template-independent nucleotide additions onto blunt-end DNA. Such non-canonical activity has been hypothesized to increase the genomic hypermutability of retroviruses including human immunodeficiency viruses. Here, we employed pre-steady state kinetics and X-ray crystallography to establish a mechanism for blunt-end additions catalyzed by Sulfolobus solfataricus Dpo4. Our kinetic studies indicated that the first blunt-end dATP incorporation was 80-fold more efficient than the second, and among natural deoxynucleotides, dATP was the preferred substrate due to its stronger intrahelical base-stacking ability. Such base-stacking contributions are supported by the 41-fold higher ground-state binding affinity of a nucleotide analog, pyrene nucleoside 5′-triphosphate, which lacks hydrogen bonding ability but possesses four conjugated aromatic rings. A 2.05 Å resolution structure of Dpo4•(blunt-end DNA)•ddATP revealed that the base and sugar of the incoming ddATP, respectively, stack against the 5′-base of the opposite strand and the 3′-base of the elongating strand. This unprecedented base-stacking pattern can be applied to subsequent blunt-end additions only if all incorporated dAMPs are extrahelical, leading to predominantly single non-templated dATP incorporation.",
        "keywords": [
            "binding affinity",
            "kinetics",
            "steady state",
            "catalysis",
            "x ray crystallography",
            "hydrogen bond",
            "binding sites",
            "dna polymerase",
            "ground state",
            "electrophoretic mobility shift assay",
            "nucleotides",
            "dna"
        ],
        "authors": [
            {
                "name": "Kevin A. Fiala",
                "org": "The Ohio State Biochemistry Program, The Ohio State University, Columbus, OH 43210, USA"
            },
            {
                "name": "Jessica A. Brown",
                "org": "The Ohio State Biochemistry Program, The Ohio State University, Columbus, OH 43210, USA"
            },
            {
                "name": "Hong Ling",
                "org": "Department of Biochemistry, University of Western Ontario, London, Ontario, Canada N6A 5C1"
            },
            {
                "name": "Ajay K. Kshetry",
                "org": "Department of Chemistry, Washington University, St. Louis, MO 63130, USA"
            },
            {
                "name": "Jun Zhang",
                "org": "Department of Biochemistry, The Ohio State University, Columbus, OH 43210, USA"
            },
            {
                "name": "John-Stephen Taylor",
                "org": "Department of Chemistry, Washington University, St. Louis, MO 63130, USA"
            },
            {
                "name": "Wei Yang",
                "org": "Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA"
            },
            {
                "name": "Zucai Suo",
                "org": ""
            }
        ],
        "venue": "Journal of Molecular Biology",
        "year": 2007
    },
    "TPfIuFud": {
        "id": "TPfIuFud",
        "title": "Initial Stages of V(D)J Recombination: The Organization of RAG1/2 and RSS DNA in the Postcleavage Complex",
        "abstract": "To obtain structural information on the early stages of V(D)J recombination, we isolated a complex of the core RAG1 and RAG2 proteins with DNA containing a pair of cleaved recombination signal sequences (RSS). Stoichiometric and molecular mass analysis established that this signal-end complex (SEC) contains two protomers each of RAG1 and RAG2. Visualization of the SEC by negative-staining electron microscopy revealed an anchor-shaped particle with approximate two-fold symmetry. Consistent with a parallel arrangement of DNA and protein subunits, the N termini of RAG1 and RAG2 are positioned at opposing ends of the complex, and the DNA chains beyond the RSS nonamer emerge from the same face of the complex, near the RAG1 N termini. These first images of the V(D)J recombinase in its postcleavage state provide a framework for modeling RAG domains and their interactions with DNA.",
        "keywords": [
            "molimmuno",
            "dna",
            "carrier proteins",
            "dna binding proteins",
            "immunohistochemistry",
            "negative staining"
        ],
        "authors": [
            {
                "name": "Gabrielle J. Grundy",
                "org": "Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA."
            },
            {
                "name": "Santiago Ramón-Maiques",
                "org": ""
            },
            {
                "name": "Emilios K. Dimitriadis",
                "org": "Laboratory of Bioengineering and Physical Science, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, MD 20892, USA"
            },
            {
                "name": "Svetlana Kotova",
                "org": "Laboratory of Bioengineering and Physical Science, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, MD 20892, USA"
            },
            {
                "name": "Christian Biertümpfel",
                "org": "Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA"
            },
            {
                "name": "J. Bernard Heymann",
                "org": "Laboratory of Structural Biology, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892, USA"
            },
            {
                "name": "Alasdair C. Steven",
                "org": "Laboratory of Structural Biology, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892, USA"
            },
            {
                "name": "Martin Gellert",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            }
        ],
        "venue": "Molecular Cell",
        "year": 2009
    },
    "ICmM5Enx": {
        "id": "ICmM5Enx",
        "title": "Structure and mechanism of human DNA polymerase [eegr]",
        "abstract": "",
        "keywords": [
            "developmental biology",
            "hydrogen",
            "genomics",
            "climate change",
            "evolution",
            "drug discovery",
            "signal transduction",
            "structural biology",
            "astronomy",
            "kinetics",
            "ecology",
            "nature",
            "pyrimidine dimers",
            "marine biology",
            "computational biology",
            "dna polymerases",
            "earth science",
            "geophysics",
            "high resolution",
            "biotechnology",
            "cell signalling",
            "biology",
            "stereochemistry",
            "genetics",
            "catalysis",
            "dna",
            "structure activity relationship",
            "nanotechnology",
            "proteomics",
            "astrophysics",
            "dna synthesis",
            "metabolomics",
            "nucleotides",
            "physics",
            "bioinformatics",
            "hydrogen bond",
            "cell cycle",
            "evolutionary biology",
            "cancer",
            "dna damage",
            "active site",
            "functional genomics",
            "medical research",
            "rna",
            "missense mutation",
            "crystal structure",
            "pharmacology",
            "dna polymerase",
            "materials science",
            "molecular biology",
            "biocatalysis",
            "medicine",
            "neuroscience",
            "quantum physics",
            "biochemistry",
            "palaeobiology",
            "transcriptomics",
            "immunology",
            "metal ion",
            "systems biology",
            "neurobiology",
            "environmental science"
        ],
        "authors": [
            {
                "name": "christian biertumpfel",
                "org": "laboratory of molecular biology"
            },
            {
                "name": "ye zhao",
                "org": "laboratory of molecular biology"
            },
            {
                "name": "y kondo",
                "org": "osaka university"
            },
            {
                "name": "santiago ramonmaiques",
                "org": "laboratory of molecular biology"
            },
            {
                "name": "mark t gregory",
                "org": "laboratory of molecular biology"
            },
            {
                "name": "j y lee",
                "org": "laboratory of molecular biology"
            },
            {
                "name": "chikahide masutani",
                "org": "osaka university"
            },
            {
                "name": "alan r lehmann",
                "org": "university of sussex"
            },
            {
                "name": "fumio hanaoka",
                "org": "osaka university"
            },
            {
                "name": "wei yang",
                "org": "sussex county community college"
            }
        ],
        "venue": "Nature",
        "year": 2010
    },
    "UPm3GB0z": {
        "id": "UPm3GB0z",
        "title": "Structure and mechanism of human DNA polymerase",
        "abstract": "The variant form of the human syndrome xeroderma pigmentosum (XPV) is caused by a deficiency in DNA polymerase (Pol), a DNA polymerase that enables replication through ultraviolet-induced pyrimidine dimers. Here we report high-resolution crystal structures of human Pol at four consecutive steps during DNA synthesis through cis-syn cyclobutane thymine dimers. Pol acts like a gη molecular splintgη to stabilize damaged DNA in a normal B-form conformation. An enlarged active site accommodates the thymine dimer with excellent stereochemistry for two-metal ion catalysis. Two residues conserved among Pol orthologues form specific hydrogen bonds with the lesion and the incoming nucleotide to assist translesion synthesis. On the basis of the structures, eight Pol missense mutations causing XPV can be rationalized as undermining the molecular splint or perturbing the active-site alignment. The structures also provide an insight into the role of Pol in replicating through D loop and DNA fragile sites. © 2010 Macmillan Publishers Limited. All rights reserved.",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Christian Biertümpfel",
                "org": "National Institute of Diabetes and Digestive and Kidney Diseases(National Institute of Diabetes and Digestive and Kidney Diseases,NIDDK,NIH),Bethesda,United States"
            },
            {
                "name": "Ye Zhao",
                "org": "National Institute of Diabetes and Digestive and Kidney Diseases(National Institute of Diabetes and Digestive and Kidney Diseases,NIDDK,NIH),Bethesda,United States"
            },
            {
                "name": "Yuji Kondo",
                "org": "Osaka University(Osaka University,Osaka Univ),Suita,Japan"
            },
            {
                "name": "Santiago Ramón-Maiques",
                "org": "National Institute of Diabetes and Digestive and Kidney Diseases(National Institute of Diabetes and Digestive and Kidney Diseases,NIDDK,NIH),Bethesda,United States"
            },
            {
                "name": "Mark T. Gregory",
                "org": "National Institute of Diabetes and Digestive and Kidney Diseases(National Institute of Diabetes and Digestive and Kidney Diseases,NIDDK,NIH),Bethesda,United States"
            },
            {
                "name": "Jaeyoung Lee",
                "org": "National Institute of Diabetes and Digestive and Kidney Diseases(National Institute of Diabetes and Digestive and Kidney Diseases,NIDDK,NIH),Bethesda,United States"
            },
            {
                "name": "Chikahide Masutani",
                "org": "Osaka University(Osaka University,Osaka Univ),Suita,Japan"
            },
            {
                "name": "Alan R. Lehmann",
                "org": "University of Sussex(University of Sussex),Sussex,United Kingdom"
            },
            {
                "name": "Fumio Hanaoka",
                "org": "Osaka University(Osaka University,Osaka Univ),Suita,Japan"
            },
            {
                "name": "Wei Yang",
                "org": "National Institute of Diabetes and Digestive and Kidney Diseases(National Institute of Diabetes and Digestive and Kidney Diseases,NIDDK,NIH),Bethesda,United States"
            }
        ],
        "venue": "Nature",
        "year": 2010
    },
    "MgbkCZ1K": {
        "id": "MgbkCZ1K",
        "title": "Organization of RAG1/2 and RSS DNA in the Post-Cleavage Complex",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Svetlana Kotova",
                "org": ""
            },
            {
                "name": "Gabriel J. Grundy",
                "org": ""
            },
            {
                "name": "Santiago Ramon-Maiques",
                "org": ""
            },
            {
                "name": "Emilios K. Dimitriadis",
                "org": ""
            },
            {
                "name": "J. Bernard Heymann",
                "org": ""
            },
            {
                "name": "Alasdair C. Steven",
                "org": ""
            },
            {
                "name": "Martin Gellert",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            }
        ],
        "venue": "Biophysical Journal",
        "year": 2010
    },
    "TlNMz3uy": {
        "id": "TlNMz3uy",
        "title": "Autoinhibition of DNA cleavage mediated by RAG1 and RAG2 is overcome by an epigenetic signal in V(D)J recombination.",
        "abstract": "Gene assembly of the variable domain of antigen receptors is initiated by DNA cleavage by the RAG1–RAG2 protein complex at sites flanking V, D, and J gene segments. Double-strand breaks are produced via a single-strand nick that is converted to a hairpin end on coding DNA and a blunt end on the neighboring recombination signal sequence. We demonstrate that the C-terminal regions of purified murine RAG1 (aa 1009–1040) and RAG2 (aa 388–520, including a plant homeodomain [PHD domain]) collaborate to inhibit the hairpinning stage of DNA cleavage. The C-terminal region of RAG2 stabilizes the RAG1/2 heterotetramer but destabilizes the RAG–DNA precleavage complex. This destabilization is reversed by binding of the PHD domain to a histone H3 peptide trimethylated on lysine 4 (H3K4me3). The addition of H3K4me3 likewise alleviates the RAG1/RAG2 C-terminus-mediated inhibition of hairpinning and the PHD-mediated inhibition of transposition activity. Thus a negative regulatory function of the noncore regions of RAG1/2 limits the RAG endonuclease activity in the absence of an activating methylated histone tail bound to the complex.",
        "keywords": [],
        "authors": [
            {
                "name": "Gabrielle J. Grundy",
                "org": "Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA."
            },
            {
                "name": "Wei Yang",
                "org": "Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892"
            },
            {
                "name": "Martin Gellert",
                "org": "Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892"
            }
        ],
        "venue": "Proceedings of the National Academy of Sciences of the United States of America",
        "year": 2010
    },
    "oxaENCiz": {
        "id": "oxaENCiz",
        "title": "Structure and mechanism of human DNA polymerase η",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Christian Biertümpfel",
                "org": ""
            },
            {
                "name": "Ye Zhao",
                "org": ""
            },
            {
                "name": "Yuji Kondo",
                "org": ""
            },
            {
                "name": "Santiago Ramón-Maiques",
                "org": ""
            },
            {
                "name": "Mark Gregory",
                "org": ""
            },
            {
                "name": "Jae Young Lee",
                "org": ""
            },
            {
                "name": "Chikahide Masutani",
                "org": ""
            },
            {
                "name": "Alan R. Lehmann",
                "org": ""
            },
            {
                "name": "Fumio Hanaoka",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            }
        ],
        "venue": "Nature",
        "year": 2010
    },
    "gYwzUUyY": {
        "id": "gYwzUUyY",
        "title": "Erratum: Structure and mechanism of human DNA polymerase η",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Christian Biertümpfel",
                "org": ""
            },
            {
                "name": "Ye Zhao",
                "org": ""
            },
            {
                "name": "Yuji Kondo",
                "org": ""
            },
            {
                "name": "Santiago Ramón-Maiques",
                "org": ""
            },
            {
                "name": "Mark Gregory",
                "org": ""
            },
            {
                "name": "Jae Young Lee",
                "org": ""
            },
            {
                "name": "Chikahide Masutani",
                "org": ""
            },
            {
                "name": "Alan R. Lehmann",
                "org": ""
            },
            {
                "name": "Fumio Hanaoka",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            }
        ],
        "venue": "Nature",
        "year": 2011
    },
    "XvYNfJKK": {
        "id": "XvYNfJKK",
        "title": "Watching DNA polymerase [eegr] make a phosphodiester bond",
        "abstract": "",
        "keywords": [
            "biophysics",
            "chemistry",
            "biochemistry",
            "structural biology"
        ],
        "authors": [
            {
                "name": "teruya nakamura",
                "org": ""
            },
            {
                "name": "ye zhao",
                "org": ""
            },
            {
                "name": "yuriko yamagata",
                "org": ""
            },
            {
                "name": "yuejin hua",
                "org": ""
            },
            {
                "name": "wei yang",
                "org": ""
            }
        ],
        "venue": "Nature",
        "year": 2012
    },
    "Wbd2wyCu": {
        "id": "Wbd2wyCu",
        "title": "Mechanism of mismatch recognition revealed by human MutSβ bound to unpaired DNA loops.",
        "abstract": "DNA mismatch repair corrects replication errors, thus reducing mutation rates and microsatellite instability. Genetic defects in this pathway cause Lynch syndrome and various cancers in humans. Binding of a mispaired or unpaired base by bacterial MutS and eukaryotic MutSα is well characterized. We report here crystal structures of human MutSβ in complex with DNA containing insertion-deletion loops (IDL) of two, three, four or six unpaired nucleotides. In contrast to eukaryotic MutSα and bacterial MutS, which bind the base of a mismatched nucleotide, MutSβ binds three phosphates in an IDL. DNA is severely bent at the IDL; unpaired bases are flipped out into the major groove and partially exposed to solvent. A normal downstream base pair can become unpaired; a single unpaired base can thereby be converted to an IDL of two nucleotides and recognized by MutSβ. The C-terminal dimerization domains form an integral part of the MutS structure and coordinate asymmetrical ATP hydrolysis by Msh2 and Msh3 with mismatch binding to signal for repair.",
        "keywords": [
            "nature structural and molecular biology",
            " science"
        ],
        "authors": [
            {
                "name": "satish c gupta",
                "org": "Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, US National Institutes of Health, Bethesda, Maryland, USA."
            },
            {
                "name": "Martin Gellert",
                "org": "laboratory of molecular biology"
            },
            {
                "name": "Wei Yang",
                "org": "laboratory of molecular biology"
            }
        ],
        "venue": "Nature structural & molecular biology",
        "year": 2012
    },
    "VAT9hZUP": {
        "id": "VAT9hZUP",
        "title": "1PT129 Watching DNA polymerase η make a phosphodiester bond(The 50th Annual Meeting of the Biophysical Society of Japan)",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Teruya Nakamura",
                "org": ""
            },
            {
                "name": "Ye Zhao",
                "org": ""
            },
            {
                "name": "Yuriko Yamagata",
                "org": ""
            },
            {
                "name": "Yue-jin Hua",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            }
        ],
        "venue": "Seibutsu Butsuri",
        "year": 2012
    },
    "kQL55hVF": {
        "id": "kQL55hVF",
        "title": "Structural basis of human DNA polymerase η-mediated chemoresistance to cisplatin.",
        "abstract": "Cisplatin (cis-diamminedichloroplatinum) and related compounds cause DNA damage and are widely used as anticancer agents. Chemoresistance to cisplatin treatment is due in part to translesion synthesis by human DNA polymerase η (hPol η). Here, we report crystal structures of hPol η complexed with intrastrand cisplatin-1,2-cross-linked DNA, representing four consecutive steps in translesion synthesis. In contrast to the generally enlarged and nondiscriminating active site of Y-family polymerases like Dpo4, Pol η is specialized for efficient bypass of UV-cross-linked pyrimidine dimers. Human Pol η differs from the yeast homolog in its binding of DNA template. To incorporate deoxycytidine opposite cisplatin-cross-linked guanines, hPol η undergoes a specific backbone rearrangement to accommodate the larger base dimer and minimizes the DNA distortion around the lesion. Our structural analyses show why Pol η is inefficient at extending primers after cisplatin lesions, which necessitates a second translesion DNA polymerase to complete bypass in vivo. A hydrophobic pocket near the primer-binding site in human Pol η is identified as a potential drug target for inhibiting translesion synthesis and, thereby, reducing chemoresistance.",
        "keywords": [
            "chemotherapy",
            "inhibitor",
            "translesion dna synthesis",
            "yeast polymerase η",
            "binding sites",
            "kinetics",
            "protein conformation",
            "drug resistance",
            "molecular structure",
            "pyrimidine dimers",
            "dna",
            "mutation"
        ],
        "authors": [
            {
                "name": "Ye Zhao",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Christian Biertümpfel",
                "org": "National Institute of Diabetes and Digestive and Kidney Diseases(National Institute of Diabetes and Digestive and Kidney Diseases,NIDDK,NIH),Bethesda,United States"
            },
            {
                "name": "Mark T Gregory",
                "org": "National Institute of Diabetes and Digestive and Kidney Diseases(National Institute of Diabetes and Digestive and Kidney Diseases,NIDDK,NIH),Bethesda,United States"
            },
            {
                "name": "Yue-Jin Hua",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Fumio Hanaoka",
                "org": "Osaka University(Osaka University,Osaka Univ),Suita,Japan"
            },
            {
                "name": "Wei Yang",
                "org": "National Institute of Diabetes and Digestive and Kidney Diseases(National Institute of Diabetes and Digestive and Kidney Diseases,NIDDK,NIH),Bethesda,United States"
            }
        ],
        "venue": "Proceedings of the National Academy of Sciences of the United States of America",
        "year": 2012
    },
    "YShhbgkE": {
        "id": "YShhbgkE",
        "title": "Reply to [ldquo]Structural requirements for RNA degradation by HIV-1 reverse transcriptase[rdquo]",
        "abstract": "",
        "keywords": [
            "x ray crystallography"
        ],
        "authors": [
            {
                "name": "mikalai lapkouski",
                "org": ""
            },
            {
                "name": "l tian",
                "org": ""
            },
            {
                "name": "jennifer t miller",
                "org": ""
            },
            {
                "name": "stuart f j le grice",
                "org": ""
            },
            {
                "name": "wei yang",
                "org": ""
            }
        ],
        "venue": "Nature Structural & Molecular Biology",
        "year": 2013
    },
    "FM9NmqHf": {
        "id": "FM9NmqHf",
        "title": "Reply to “Structural requirements for RNA degradation by HIV-1 reverse transcriptase”",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "wei yang",
                "org": ""
            },
            {
                "name": "mikalai lapkouski",
                "org": ""
            },
            {
                "name": "l tian",
                "org": ""
            },
            {
                "name": "jennifer t miller",
                "org": ""
            },
            {
                "name": "stuart f j le grice",
                "org": ""
            }
        ],
        "venue": "Nature Structural & Molecular Biology",
        "year": 2013
    },
    "yGC46Rk7": {
        "id": "yGC46Rk7",
        "title": "Novel insights from structural analysis of lentiviral and gammaretroviral reverse transcriptases in complex with RNA/DNA hybrids",
        "abstract": "",
        "keywords": [
            "biomedical research",
            "bioinformatics"
        ],
        "authors": [
            {
                "name": "stuart le grice",
                "org": "national cancer institute"
            },
            {
                "name": "mikalai lapkouski",
                "org": "national institute of diabetes and digestive and kidney diseases"
            },
            {
                "name": "l tian",
                "org": "national institute of diabetes and digestive and kidney diseases"
            },
            {
                "name": "jennifer t miller",
                "org": "national cancer institute"
            },
            {
                "name": "elzbieta nowak",
                "org": "international institute of minnesota"
            },
            {
                "name": "wojciech potrzebowski",
                "org": "international institute of minnesota"
            },
            {
                "name": "peter v konarev",
                "org": "European Molecular Biology Laboratory,Hamburg,Germany"
            },
            {
                "name": "jason w rausch",
                "org": "national cancer institute"
            },
            {
                "name": "marion k bona",
                "org": "national cancer institute"
            },
            {
                "name": "dmitri i svergun",
                "org": "European Molecular Biology Laboratory,Hamburg,Germany"
            },
            {
                "name": "janusz m bujnicki",
                "org": "international institute of minnesota"
            },
            {
                "name": "marcin nowotny",
                "org": "international institute of minnesota"
            },
            {
                "name": "wei yang",
                "org": "national institute of diabetes and digestive and kidney diseases"
            }
        ],
        "venue": "Retrovirology",
        "year": 2013
    },
    "0vCtBKTE": {
        "id": "0vCtBKTE",
        "title": "Mechanism of somatic hypermutation at the WA motif by human DNA polymerase η.",
        "abstract": "Somatic hypermutation is programmed base substitutions in the variable regions of Ig genes for high-affinity antibody generation. Two motifs, RGYW and WA (R, purine; Y, pyrimidine; W, A or T), have been found to be somatic hypermutation hotspots. Overwhelming evidence suggests that DNA polymerase η (Pol η) is responsible for converting the WA motif to WG by misincorporating dGTP opposite the templating T. To elucidate the molecular mechanism, crystal structures and kinetics of human Pol η substituting dGTP for dATP in four sequence contexts, TA, AA, GA, and CA, have been determined and compared. The T:dGTP wobble base pair is stabilized by Gln-38 and Arg-61, two uniquely conserved residues among Pol η. Weak base paring of the W (T:A or A:T) at the primer end and their distinct interactions with Pol η lead to misincorporation of G in the WA motif. Between two WA motifs, our kinetic and structural data indicate that A-to-G mutation occurs more readily in the TA context than AA. Finally, Pol η can extend the T:G mispair efficiently to complete the mutagenesis.",
        "keywords": [
            "a-to-g transition",
            "immunoglobulin",
            "π–cation stacking",
            "immunoglobulins",
            "kinetics",
            "mutation"
        ],
        "authors": [
            {
                "name": "Ye Zhao",
                "org": "Institute of Nuclear-Agricultural Sciences, Zhejiang University, Hangzhou 310029, China;;Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892"
            },
            {
                "name": "Mark T Gregory",
                "org": "Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892"
            },
            {
                "name": "Christian Biertümpfel",
                "org": "Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892"
            },
            {
                "name": "Yue-Jin Hua",
                "org": "Institute of Nuclear-Agricultural Sciences, Zhejiang University, Hangzhou 310029, China;"
            },
            {
                "name": "Fumio Hanaoka",
                "org": "Faculty of Science, Gakushuin University, Tokyo 171-8588, Japan"
            },
            {
                "name": "Wei Yang",
                "org": "Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892"
            }
        ],
        "venue": "Proceedings of the National Academy of Sciences of the United States of America",
        "year": 2013
    },
    "mA2dnzID": {
        "id": "mA2dnzID",
        "title": "MuB is an AAA+ ATPase that forms helical filaments to control target selection for DNA transposition.",
        "abstract": "MuB is an ATP-dependent nonspecific DNA-binding protein that regulates the activity of the MuA transposase and captures target DNA for transposition. Mechanistic understanding of MuB function has previously been hindered by MuB's poor solubility. Here we combine bioinformatic, mutagenic, biochemical, and electron microscopic analyses to unmask the structure and function of MuB. We demonstrate that MuB is an ATPase associated with diverse cellular activities (AAA+ ATPase) and forms ATP-dependent filaments with or without DNA. We also identify critical residues for MuB's ATPase, DNA binding, protein polymerization, and MuA interaction activities. Using single-particle electron microscopy, we show that MuB assembles into a helical filament, which binds the DNA in the axial channel. The helical parameters of the MuB filament do not match those of the coated DNA. Despite this protein-DNA symmetry mismatch, MuB does not deform the DNA duplex. These findings, together with the influence of MuB filament size on strand-transfer efficiency, lead to a model in which MuB-imposed symmetry transiently deforms the DNA at the boundary of the MuB filament and results in a bent DNA favored by MuA for transposition.",
        "keywords": [
            "phage mu",
            "nucleoprotein filament",
            "electron microscopy",
            "c terminal domain"
        ],
        "authors": [
            {
                "name": "Naoko Mizuno",
                "org": "Laboratory of Structural Biology, National Institute of Arthritis, Musculoskeletal, and Skin Diseases and;Max Planck Institute of Biochemistry, D-82152 Martinsried, Germany;"
            },
            {
                "name": "Marija Dramićanin",
                "org": "Structural Bases of Genome Integrity Group, Structural Biology and Biocomputing Programme, Spanish National Cancer Research Centre (CNIO), 28029 Madrid, Spain;"
            },
            {
                "name": "Michiyo Mizuuchi",
                "org": "Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892;"
            },
            {
                "name": "Julia Adam",
                "org": "Max Planck Institute of Biochemistry, D-82152 Martinsried, Germany;"
            },
            {
                "name": "Yi Wang",
                "org": "Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892;;Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030"
            },
            {
                "name": "Yong-Woon Han",
                "org": "Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892;;Institute for Integrated Cell-Material Science, Kyoto University, Kyoto 606-8501, Japan"
            },
            {
                "name": "Wei Yang",
                "org": "Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892;"
            },
            {
                "name": "Alasdair C Steven",
                "org": "Laboratory of Structural Biology, National Institute of Arthritis, Musculoskeletal, and Skin Diseases and"
            },
            {
                "name": "Kiyoshi Mizuuchi",
                "org": "Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892;"
            },
            {
                "name": "Santiago Ramón-Maiques",
                "org": "Structural Bases of Genome Integrity Group, Structural Biology and Biocomputing Programme, Spanish National Cancer Research Centre (CNIO), 28029 Madrid, Spain;;Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892;"
            }
        ],
        "venue": "Proceedings of the National Academy of Sciences of the United States of America",
        "year": 2013
    },
    "99MiwAvS": {
        "id": "99MiwAvS",
        "title": "Complexes of HIV-1 RT, NNRTI and RNA/DNA hybrid reveal a structure compatible with RNA degradation",
        "abstract": "",
        "keywords": [
            "crystallization",
            "protein conformation",
            "x ray diffraction"
        ],
        "authors": [
            {
                "name": "mikalai lapkouski",
                "org": ""
            },
            {
                "name": "l tian",
                "org": ""
            },
            {
                "name": "jennifer t miller",
                "org": ""
            },
            {
                "name": "stuart f j le grice",
                "org": ""
            },
            {
                "name": "wei yang",
                "org": ""
            }
        ],
        "venue": "Nature Structural & Molecular Biology",
        "year": 2013
    },
    "3WU1gSld": {
        "id": "3WU1gSld",
        "title": "RNA degradation versus DNA synthesis by HIV-1 RT",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Mikalai Lapkouski",
                "org": ""
            },
            {
                "name": "Lan Tian",
                "org": ""
            },
            {
                "name": "Jennifer T. Miller",
                "org": ""
            },
            {
                "name": "Stuart F. J. Le Grice",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            }
        ],
        "venue": "Nature Structural & Molecular Biology",
        "year": 2013
    },
    "vT4Vm1Ok": {
        "id": "vT4Vm1Ok",
        "title": "Molecular basis for unidirectional scaffold switching of human Plk4 in centriole biogenesis.",
        "abstract": "",
        "keywords": [
            "structural",
            "biology",
            "nature",
            "x ray crystallography",
            "mitosis",
            "molecular"
        ],
        "authors": [
            {
                "name": "s park",
                "org": ""
            },
            {
                "name": "jungeun park",
                "org": ""
            },
            {
                "name": "taesung kim",
                "org": ""
            },
            {
                "name": "j h kim",
                "org": ""
            },
            {
                "name": "mijeong kwak",
                "org": ""
            },
            {
                "name": "bonsu ku",
                "org": ""
            },
            {
                "name": "l tian",
                "org": ""
            },
            {
                "name": "ravichandran n murugan",
                "org": ""
            },
            {
                "name": "mija ahn",
                "org": ""
            },
            {
                "name": "s komiya",
                "org": ""
            },
            {
                "name": "hironobu hojo",
                "org": ""
            },
            {
                "name": "namhyung kim",
                "org": ""
            },
            {
                "name": "bo yeon kim",
                "org": ""
            },
            {
                "name": "jeong kyu bang",
                "org": ""
            },
            {
                "name": "r l erikson",
                "org": ""
            },
            {
                "name": "k w lee",
                "org": ""
            },
            {
                "name": "seung jun kim",
                "org": ""
            },
            {
                "name": "byungha oh",
                "org": ""
            },
            {
                "name": "wei yang",
                "org": ""
            }
        ],
        "venue": "Nature Structural & Molecular Biology",
        "year": 2014
    },
    "x0z974c4": {
        "id": "x0z974c4",
        "title": "Mechanism of mismatch-provoked excision in a defined mismatch repair system (735.14)",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "sanghee lee",
                "org": "the graduate center cuny"
            },
            {
                "name": "liya gu",
                "org": "the graduate center cuny"
            },
            {
                "name": "wei yang",
                "org": "national institute of diabetes and digestive and kidney diseases"
            },
            {
                "name": "guomin li",
                "org": "the graduate center cuny"
            }
        ],
        "venue": "The FASEB Journal",
        "year": 2014
    },
    "Tln1No9m": {
        "id": "Tln1No9m",
        "title": "Efficient polymer light emitting diodes with metal fluoride/Al cathodes",
        "abstract": "We reported efficient polymer light emitting diodes with alkali and alkaline earth metal fluoride Al cathodes. The quantum efficiencies of these devices are more than two orders of magnitude higher than those in devices without fluoride layer, comparable to the best data reported with similar electroluminescent polymers. The mechanism of the metal fluoride/Al bilayer cathodes was also discussed based on photovoltaic, ac impedance, and photoluminescence efficiency measurement. © 2001 American Institute of Physics.",
        "keywords": [
            "alkaline earth metal",
            "light emitting diode",
            "organic material",
            "electroluminescence",
            "quantum efficiency"
        ],
        "authors": [
            {
                "name": "Xiaohui Yang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Yueqi Mo",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Wei Yang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Gang Yu",
                "org": "DuPont(E. I. du Pont de Nemours and Company),Wilmington,United States"
            },
            {
                "name": "Yong Cao",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            }
        ],
        "venue": "Applied Physics Letters",
        "year": 2001
    },
    "uEE04Qu5": {
        "id": "uEE04Qu5",
        "title": "Novel Red Electroluminescent Polymers Derived from Carbazole and 3,6-Bis(2-thienyl)-1,2,7-benzothiadiazole",
        "abstract": "",
        "keywords": [
            "electroluminescence",
            "luminescence"
        ],
        "authors": [
            {
                "name": "Jian Huang",
                "org": ""
            },
            {
                "name": "Yishe Xu",
                "org": ""
            },
            {
                "name": "Qiong Hou",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Ming Yuan",
                "org": ""
            },
            {
                "name": "Yong Cao",
                "org": ""
            }
        ],
        "venue": "Macromolecular Rapid Communications",
        "year": 2002
    },
    "IqDbjStC": {
        "id": "IqDbjStC",
        "title": "Novel Electroluminescent Polymers Derived from Carbazole and Benzothiadiazole",
        "abstract": "",
        "keywords": [
            "electroluminescence"
        ],
        "authors": [
            {
                "name": "Jian Huang",
                "org": ""
            },
            {
                "name": "Yuhua Niu",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Yueqi Mo",
                "org": ""
            },
            {
                "name": "Ming Yuan",
                "org": ""
            },
            {
                "name": "Yong Cao",
                "org": ""
            }
        ],
        "venue": "Macromolecules",
        "year": 2002
    },
    "zKeZtLu2": {
        "id": "zKeZtLu2",
        "title": "Novel red electroluminescent polymers derived from carbazole and 4,7-bis(2-thienyl)-2,1,3-benzothiadiazole",
        "abstract": "A series of novel carbazole-based soluble copolymers of different composition was synthesized by Suzuki coupling reaction. Efficient energy transfer from the wide-band-gap segment polycarbazole due to exciton trapping on narrow-band-gap bis(thienyl)benzothiadiazole sites has been observed. Maximum electroluminescence wavelengths of the copolymers varied between 668 nm and 716 nm, and the external quantum efficiency for copolymer devices is 0.3% for copolymers with 20% benzothiadiazole content.",
        "keywords": [
            "4",
            "7-bis(2-thienyl)-2",
            "1",
            "3-benzothiadiazole",
            "Exciton confinement",
            "Light-emitting diodes (LED)",
            "Luminescence",
            "Polycarbazole"
        ],
        "authors": [
            {
                "name": "Jian Huang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Yishe Xu",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Qiong Hou",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Wei Yang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Ming Yuan",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Yong Cao",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            }
        ],
        "venue": "Macromolecular Rapid Communications",
        "year": 2002
    },
    "Md5eNHf3": {
        "id": "Md5eNHf3",
        "title": "High-efficiency blue-light-emitting diodes with narrow linewidth based on blends of poly[2-(2 ′-ethylhexyloxy)-1,4-phenylene] and poly(dialkylfluorene-co-dibenzothiophene)",
        "abstract": "High-efficiency blue light-emitting diodes were realized based on the blends of poly(dialkylfluorene-co-dibenzothiophene) in poly[2-(2 ′-ethylhexyloxy)-1,4-phenylene] host. The external quantum efficiency was increased by about four times, relative to devices with the guest polymer alone. Much more balanced carrier injection was assigned as the origin of the performance enhancement. Dramatic narrowing on linewidth, with the full width at half maximum reduced from more than 40 to 14.3 nm, produced more pure blue emission. © 2002 American Institute of Physics. © 2002 American Institute of Physics.",
        "keywords": [
            "electroluminescence",
            "full width at half maximum",
            "external quantum efficiency"
        ],
        "authors": [
            {
                "name": "YuHua Niu",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Wei Yang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Yong Cao",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            }
        ],
        "venue": "Applied Physics Letters",
        "year": 2002
    },
    "XR2jmQpO": {
        "id": "XR2jmQpO",
        "title": "Highly efficient electrophosphorescent devices based on conjugated polymers doped with iridium complexes",
        "abstract": "Iridium complexes with alkyl substituted 2-phenylpyridine, Ir(Bu-PPy) 3, were synthesized. Polymer light emitting diodes with Ir complexes as the guest materials and the substituted polyphenylenes as the host were fabricated. Ir(Bu-PPy) 3-doped Poly(2-(6-cyano-6-methyl)- heptyloxy-1,4-phenylene) (CNPPP) device showed generally higher quantum efficiency (QE) than that of Ir(PPy) 3-doped device for a given dopant concentration. More importantly, the addition of butyl group into phenylpyridine ligand significantly suppresses the decay of device efficiency at high current density. For instance, for devices made with Ir(Bu-PPy) 3-doped CNPPP: the maximum external quantum efficiency, QE, and luminance efficiency reached 5.1% ph/el and 12 cd/A, respectively, at 800 cd/m 2 and maintained at 4.2% ph/el and 10 cd/A, respectively, at 2500 cd/m 2. © 2002 American Institute of Physics.",
        "keywords": [
            "organic material",
            "light emitting diode",
            "quantum efficiency",
            "current density",
            "external quantum efficiency",
            "liquid crystal"
        ],
        "authors": [
            {
                "name": "Weiguo Zhu",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Yueqi Mo",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Min Yuan",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Wei Yang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Yong Cao",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            }
        ],
        "venue": "Applied Physics Letters",
        "year": 2002
    },
    "LbrtAa95": {
        "id": "LbrtAa95",
        "title": "Novel red-emitting fluorene-based copolymers",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Qiong Hou",
                "org": ""
            },
            {
                "name": "Yishe Xu",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Min Yuan",
                "org": ""
            },
            {
                "name": "Junbiao Peng",
                "org": ""
            },
            {
                "name": "Yong Cao",
                "org": ""
            }
        ],
        "venue": "Journal of Materials Chemistry",
        "year": 2002
    },
    "xz8aV09M": {
        "id": "xz8aV09M",
        "title": "Novel energy transfer carbazole-based light-emitting copolymers",
        "abstract": "A series of novel electroluminescent polycarbazole-based main chain copolymers with varieties of aromatic rings and heterocycles as comonomer has been synthesized by Suzuki coupling reaction. The copolymers ate soluble in common organic solvents and are highly fluorescent. Conjugated carbazole segment provides good hole-injection and hole-transport properties. Narrow band-gap heterocycles and aromatic rings, such as benzothiadiazole, benzosel1enadiazole, 4,7-dithien-2-yl-2,1,3-benzothiadiazole, thiophenes and anthracene in less than 50% of molar ratio in the copolymer were incorporated as a trapping center. The efficient energy transfer due to exciton trapping on the narrow band-gap sites was observed. The emission color can be tuned in entire visible region by carefully selecting the narrow band-gap comonomers. The use of conjugated polycarbazole as wide band-gap segment could provide a new way to combine good hole-injection properties along with color tuning ability.",
        "keywords": [
            "Carbazole",
            "Electroluminescent",
            "Energy-transfer"
        ],
        "authors": [
            {
                "name": "Jian Huang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "YuHua Niu",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Wei Yang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Qiong Hou",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Yishe Xu",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Min Yuan",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Yong Cao",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            }
        ],
        "venue": "Acta Chimica Sinica",
        "year": 2003
    },
    "OxJwgz9S": {
        "id": "OxJwgz9S",
        "title": "Synthesis of new iridium complexes and their electrophosphorescent properties in polymer light-emitting diodes",
        "abstract": "",
        "keywords": [
            "light emitting diode"
        ],
        "authors": [
            {
                "name": "Weiguo Zhu",
                "org": ""
            },
            {
                "name": "Chuanzhen Liu",
                "org": ""
            },
            {
                "name": "Lijun Su",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Ming Yuan",
                "org": ""
            },
            {
                "name": "Yong Cao",
                "org": ""
            }
        ],
        "venue": "Journal of Materials Chemistry",
        "year": 2003
    },
    "WpHpTvTU": {
        "id": "WpHpTvTU",
        "title": "Synthesis and electroluminescent properties of copolymer of fluorene and thiophene",
        "abstract": "The emission color of polyfluorenes can be turned over entire visible region by incorporating comonomer into polyfluorene backbone. In this paper, we demonstrate color tuning in polyfluorene derivatives by incorporating thiophene into the polyfluorene main chain. High molecular weight ( Mn = 6000-53000), readily soluable copolymers of different compositions were prepared from 2,7-dibromo-9,9-dioctylfluorene (DOF), 2,7-bis(4,4,5, 5-tetramethyl-1, 3, 2-dioxaborolan-2-yl)-9, 9-dioctylfluorene and a narrow band gap comonomer 2, 5-dibromothiophene using palladium catalyzed Suzuki coupling methods. The comonomer feed ratios of DOF to thiophene were 95:5,90:10,85:15,70:30 and 50:50 respectively. The resulting copolymers are soluble in common organic solvents, such as THF and CHCl3. The actual molar ratios of DOF to thiophene in the copolymers were estimated by means of elemental analysis. The results indicate that the actual ratio of DOF to thiophene in the copolymer is very close to the feed ratio. The electrochemical, optical, photoluminescent (PL) and electroluminescent (EL) properties of the copolymers were studied. Cyclic voltammogram (CV) indicates that the LUMO level of the copolymers is close to that of the PF homopolymer, and it keeps almost constant for copolymers with different thiophene content. The HOMO level slightly decreases with increasing the thiophene content in the copolymer. PL and EL peaks are red-shifting with increasing the thiophene content. The maximal EL emission wavelength of the copolymers is red-shifted from 490 nm to 541 nm, when the thiophene content increases from 5% to 50%. Both PL and EL etticiencies decrease with increasing the thiophene content. The highest external EL quantum efficiency 0.45% was obtained from the device at the thiophene ratio of 5% and 10%, respectively. The results indicate that the use of conjugated polyfluorene as wide band-gap segment with a small amount (1%-5%) of narrow band-gap dopant in the molecular level could provide a new way to combine high quantum efficiency along with color turning ability.",
        "keywords": [
            "Copolymers",
            "Electroluminescent",
            "Fluorene",
            "Red-shifted",
            "Suzuki coupling",
            "Thiophene"
        ],
        "authors": [
            {
                "name": "Qiong Hou",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "YuHua Niu",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Wei Yang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Renqiang Yang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Min Yuan",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Yong Cao",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            }
        ],
        "venue": "Acta Polymerica Sinica",
        "year": 2003
    },
    "869SCSeU": {
        "id": "869SCSeU",
        "title": "Synthesis and Optical and Electroluminescent Properties of Novel Conjugated Copolymers Derived from Fluorene and Benzoselenadiazole",
        "abstract": "",
        "keywords": [
            "electroluminescence"
        ],
        "authors": [
            {
                "name": "Renqiang Yang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Renyu Tian",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Qiong Hou",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Wei Yang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Yong Cao",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            }
        ],
        "venue": "Macromolecules",
        "year": 2003
    },
    "XS7pBcLf": {
        "id": "XS7pBcLf",
        "title": "Improvement of color purity in blue-emitting polyfluorene by copolymerization with dibenzothiophene",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Qiong Hou",
                "org": ""
            },
            {
                "name": "Chuanzhen Liu",
                "org": ""
            },
            {
                "name": "Yuhua Niu",
                "org": ""
            },
            {
                "name": "Jian Huang",
                "org": ""
            },
            {
                "name": "Renqiang Yang",
                "org": ""
            },
            {
                "name": "Yong Cao",
                "org": ""
            }
        ],
        "venue": "Journal of Materials Chemistry",
        "year": 2003
    },
    "zPDMc5aB": {
        "id": "zPDMc5aB",
        "title": "Synthesis and electroluminescent properties of fluorene-based copolymers",
        "abstract": "A series of novel soluble conjugated copolymers derived from 9,9-dioctylfluorene (DOF) with 4,7-dithien-2-yl-2,1, 3-benzothiadiazole (DBT)) were synthesized by palladium-catalyzed Suzuki coupling reaction. The copolymers of DOF-co-DBT emit saturated red emission which is red-shifted with the increasing DBT contents. Highest external electroluminescence (EL) quantum efficiency of the devices based on the copolymers exceeds 1.4% for copolymer with 15% DBT content. The results indicate that the DOF-co-DBT copolymers are promising candidate for full-colour polymer flat panel display. © 2003 Elsevier Science B.V. All rights reserved.",
        "keywords": [
            "3-benzothiadiazole",
            "4",
            "7-dithien-2-yl-2",
            " 1",
            "Fluorene",
            "Light-emitting copolymers",
            "Suzuki coupling"
        ],
        "authors": [
            {
                "name": "O. Hou",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Yishe Xu",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Wei Yang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Renqiang Yang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Min Yuan",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Junbiao Peng",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Yong Cao",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            }
        ],
        "venue": "Synthetic Metals",
        "year": 2003
    },
    "7zajjpc8": {
        "id": "7zajjpc8",
        "title": "Influences of end-groups and thermal effect on the red-shifted emission in the poly (9, 9-dioctylfluorene) light emitting diodes",
        "abstract": "Blue polymer light emitting diode based on poly (9,9-dioctylfluorene) (PFO) has been demonstrated. The effects of end-group of PFO on the optoelectronic characteristics of the devices are explored. Our results suggest that end-group functions as both the carrier trap and the luminescence quenching center. Both the end-group and the thermal effect contribute to the red-shifted emission. © 2003 Elsevier Science B.V. All rights reserved.",
        "keywords": [
            "end-group",
            "polyfluorene",
            "red-shifted emission",
            "thermal effect",
            "light emitting diode"
        ],
        "authors": [
            {
                "name": "Xiaohui Yang",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Ming Yuan",
                "org": ""
            },
            {
                "name": "Qiong Hou",
                "org": ""
            },
            {
                "name": "Jian Huang",
                "org": ""
            },
            {
                "name": "Xingrong Zeng",
                "org": ""
            },
            {
                "name": "Yong Cao",
                "org": ""
            }
        ],
        "venue": "Synthetic Metals",
        "year": 2003
    },
    "0JVk54PZ": {
        "id": "0JVk54PZ",
        "title": "Novel Highly Electroluminescent Fluorene-based Copolymers",
        "abstract": "We report the first synthesis of a series of novel conjugated copolymers derived from 9,9-dioctylfluorene (DOF) and 2,1,3-benzoselenadiazole (BSeD) synthesized by palladium-catalyzed Suzuki coupling reaction. The comonomer ratios (DOF:BSeD) were 98:2, 85:15, and 50:50 respectively. The copolymers were soluble in common organic solvents and highly fluorescent in solid state. The maximal EL emissions of the devices based on the copolymers are in the range of red, and slightly red-shifted gradually with increasing BSeD's contents. The maximal external quantum efficiency of the devices reaches 1.0%. © 2003 Elsevier Science B.V. All rights reserved.",
        "keywords": [
            "benzoselenadiazole",
            "copolymer",
            "electroluminescent",
            "fluorene",
            "light-emitting diode",
            "electroluminescence"
        ],
        "authors": [
            {
                "name": "Renqiang Yang",
                "org": ""
            },
            {
                "name": "Renyu Tian",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Qiong Hou",
                "org": ""
            },
            {
                "name": "Yong Cao",
                "org": ""
            }
        ],
        "venue": "Synthetic Metals",
        "year": 2003
    },
    "vPpqCnIx": {
        "id": "vPpqCnIx",
        "title": "The study on photoluminescence and electroluminescence of 9,9-dialkyfluorene and selenophene copolymers",
        "abstract": "Polymer light emitting diodes based on 9,9-dialkyfluorene and selenophene copolymers with different selenophene content were fabricated. Influence of the selenophene content on device performances was studied. Device performances have been improved by modification of the cathodic interface and polymer blend.",
        "keywords": [
            "9",
            "9-Dialkyfluorene and selenophene copolymers",
            "Blend",
            "Modification of the cathodic interface"
        ],
        "authors": [
            {
                "name": "Renyu Tian",
                "org": "Institute of Polymer Optoelectronic Materials and Devices(Institute of Polymer Optoelectronic Materials and Devices),Guangzhou,China"
            },
            {
                "name": "Renqiang Yang",
                "org": "Institute of Polymer Optoelectronic Materials and Devices(Institute of Polymer Optoelectronic Materials and Devices),Guangzhou,China"
            },
            {
                "name": "Wei Yang",
                "org": "Institute of Polymer Optoelectronic Materials and Devices(Institute of Polymer Optoelectronic Materials and Devices),Guangzhou,China"
            },
            {
                "name": "Junbiao Peng",
                "org": "Institute of Polymer Optoelectronic Materials and Devices(Institute of Polymer Optoelectronic Materials and Devices),Guangzhou,China"
            },
            {
                "name": "Yong Cao",
                "org": "Institute of Polymer Optoelectronic Materials and Devices(Institute of Polymer Optoelectronic Materials and Devices),Guangzhou,China"
            }
        ],
        "venue": "Chemistry Bulletin / Huaxue Tongbao",
        "year": 2004
    },
    "xhs4pBxd": {
        "id": "xhs4pBxd",
        "title": "High-efficiency, environment-friendly electroluminescent polymers with stable high work function metal as a cathode: green- and yellow-emitting conjugated polyfluorene polyelectrolytes and their neutral precursors.",
        "abstract": "A series of aminoalkyl-substituted polyfluorene copolymers with benzothiadiazole (BTDZ) of different content were synthesized by Suzuki coupling reaction, and their quaternized ammonium polyelectrolyte derivatives were obtained through a postpolymerization treatment on the terminal amino groups. Copolymers are soluble in environmentally friendlier solvents, such as alcohols. It was found that the efficient energy transfer occurs by exciton trapping on the narrow band gap BTDZ site under UV illumination. Only 1% of BTDZ content is needed to completely quench a fluorene emission for both the neutral and the quaternized copolymers in the neat film. Absolute PL efficiencies of copolymer films were greatly enhanced as a result of the suppression of excimer formation. Light-emitting devices fabricated from these copolymers show high external quantum efficiencies over 3% and 1% for the neutral precursor and the quaternized copolymers, respectively, with high work function metals such as Al as a cathode. To the best of our knowledge, this is the first report on an electroluminescent polymer which bears the high EL efficiency, the electron-injection ability from high work function metals, and the solubility in environment-friendly solvents at the same time. These features make them a promising candidate for the next generation of light-emitting copolymers in PLED flat panel display application.",
        "keywords": [
            "work function",
            "electroluminescence"
        ],
        "authors": [
            {
                "name": "Fei Huang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Lintao Hou",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Hongbin Wu",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Xiaohui Wang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Huilin Shen",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Wei Cao",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Wei Yang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Yong Cao",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            }
        ],
        "venue": "Journal of the American Chemical Society",
        "year": 2004
    },
    "b7q0X8SS": {
        "id": "b7q0X8SS",
        "title": "Synthesis and Electroluminescent Properties of High-Efficiency Saturated Red Emitter Based on Copolymers from Fluorene and 4,7-Di(4-hexylthien-2-yl)-2,1,3-benzothiadiazole",
        "abstract": "",
        "keywords": [
            "electroluminescence"
        ],
        "authors": [
            {
                "name": "Qiong Hou",
                "org": ""
            },
            {
                "name": "Qingmei Zhou",
                "org": ""
            },
            {
                "name": "Yong Zhang",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Renqiang Yang",
                "org": ""
            },
            {
                "name": "Yong Cao",
                "org": ""
            }
        ],
        "venue": "Macromolecules",
        "year": 2004
    },
    "zQPepiFQ": {
        "id": "zQPepiFQ",
        "title": "23.1: Efficient Electron Injection from Bilayer Cathode with High Work Function Metal",
        "abstract": "",
        "keywords": [
            "work function"
        ],
        "authors": [
            {
                "name": "Yong Cao",
                "org": ""
            },
            {
                "name": "Hongbin Wu",
                "org": ""
            },
            {
                "name": "Fei Huang",
                "org": ""
            },
            {
                "name": "Yueqi Mo",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            }
        ],
        "venue": "Sid Symposium Digest of Technical Papers",
        "year": 2004
    },
    "6GOliB6k": {
        "id": "6GOliB6k",
        "title": "Synthesis and spectral characteristics of copolymers of fluorene and oxadiazole",
        "abstract": "Linear and hyperbranched copolymers of fluorene and oxadiazole with high molecular weight are synthesized by a polycondensation reaction. The resulting copolymers are soluble in common organic solvents. Their UV-Vis absorption spectra show two sharp bands at about 398 and 376nm in solid film. The two polymers fluorescence in the blue-light range with quantum yields of about 16% in solid film. The CV measurements show that the LUMO levels of them are much higher than that of the fluorene homopolymer and close to the work functions of typical cathode materials such as Ca and Mg, indicating a favorable electron injection and transport property of these copolymers.",
        "keywords": [
            "Fluorene-oxadiazole polymer",
            "PL properties",
            "Synthesis"
        ],
        "authors": [
            {
                "name": "Jialiang Ke",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Wei Yang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Changyun Jiang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Chi Zhang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Qiong Hou",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            }
        ],
        "venue": "Chemistry Bulletin / Huaxue Tongbao",
        "year": 2004
    },
    "fKrgT8ye": {
        "id": "fKrgT8ye",
        "title": "Novel Electroluminescent Conjugated Polyelectrolytes Based on Polyfluorene",
        "abstract": "",
        "keywords": [
            "electroluminescence"
        ],
        "authors": [
            {
                "name": "Fei Huang",
                "org": ""
            },
            {
                "name": "Hongbin Wu",
                "org": ""
            },
            {
                "name": "Deli Wang",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Yong Cao",
                "org": ""
            }
        ],
        "venue": "Chemistry of Materials",
        "year": 2004
    },
    "z6KYy22Z": {
        "id": "z6KYy22Z",
        "title": "High-Efficiency Saturated Red Emitting Polymers Derived from Fluorene and Naphthoselenadiazole",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Jian Yang",
                "org": ""
            },
            {
                "name": "Changyun Jiang",
                "org": ""
            },
            {
                "name": "Yong Zhang",
                "org": ""
            },
            {
                "name": "Renqiang Yang",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Qiong Hou",
                "org": ""
            },
            {
                "name": "Yong Cao",
                "org": ""
            }
        ],
        "venue": "Macromolecules",
        "year": 2004
    },
    "rhEQXqCl": {
        "id": "rhEQXqCl",
        "title": "Synthesis and luminescencent properties of TPA-fluorene copolymers",
        "abstract": "A series of high molecular weight, readily soluble copolymers of 9,9-di-2-ethylhexyifluorene with triphenylamine (TPA) (less than or equal to 50(mol)%) are synthesized by Suzuki polycondensation. The introduction of TPA unit into polyfluorene backbone improves the hole transfer ability and depresses the excimer formation. Narrow blue EL emission is obtained for copolymer with TPA Content of 20(mol)%. External quantum efficiency is moderately high (1.28%) for such a blue emitter. The threshold voltages of devices from copolymers with TPA content of less than 20(mol)% are low in the range of 4̃5V based on the device configuration: ITO/PEDOT/polymer/Ba/Al. The results indicate that fluorene-co-triphenylamine copolymers are promising blue-emitting electroluminescent materials.",
        "keywords": [
            "Polyfluorene",
            "Suzuki polycondensation",
            "TPA"
        ],
        "authors": [
            {
                "name": "Zhigang Guo",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Qiong Hou",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Changyun Jiang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Chi Zhang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Renqang Yang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Wei Yang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            }
        ],
        "venue": "Chemistry Bulletin / Huaxue Tongbao",
        "year": 2004
    },
    "DmTBSqzM": {
        "id": "DmTBSqzM",
        "title": "Enhancement of color purity in blue-emitting fluorene–pyridine-based copolymers by controlling the chain rigidity and effective conjugation length",
        "abstract": "A series of high molecular weight, readily soluble copolymers of 9,9-dioctylfluorene with pyridine (less than or equal to 50 mol%) are synthesized by Suzuki polycondensation. Copolymers emit blue light and exhibit high PL efficiency. PL efficiencies show the maximum at 3,5-pyridine content of around 30 mol% in the copolymer. With further the increase of meta -linkage contents, PL efficiencies decrease rapidly to15% for alternating copolymer. Cyclic voltammetry investigation reveals that LUMO levels of copolymers increase with the increase of pyridine content. The introduction of pyridine unit at 3,5-position into polyfluorene backbone significantly depresses the excimer formation. The intensity of excimer emission decreases with the increase of 3,5-pyridine contents. Narrow and pure blue EL emission is obtained for copolymer with pyridine content of 40 mol%. External quantum efficiency is moderately high (0.4–0.5%) for such a pure blue emitter. The threshold voltages of devices from copolymers with the pyridine content of less than 40 mol% are low in the range of 5–6 V based on the device configuration: ITO/PEDOT/polymer/Ba/Al. The results indicate that fluorene- co -3,5-pyridine copolymers are promising blue-emitting electroluminescent materials. Keywords Fluorene Blue-emitting copolymer Color purity 1 Introduction Conjugated polymers have recently attracted great attention due to their possible utilization in flat panel displays [1] . Following the discovery of electroluminescence (EL) in poly( p -phenylenevinylene) (PPV) [2] , various EL conjugated polymers have been synthesized [3–5] . Of them, blue-emitting polymers are still far away from specifications required by full color displays due to large band-gap, high oxidation potential and low electron affinities for blue EL polymers. Poly(9-alkylfluorene)s are promising electroluminescent polymer for light-emitting diodes because of their thermal and chemical stability, good solubility in the common organic solvents, and high fluorescent quantum yields in the solid-state [6] . Poly(9,9-dioctylfluorene) (PDOF) exhibits very good, non-dispersive hole transport, but poor electron transport [7,8] . To achieve high quantum efficiency in a PDOF light-emitting diode, it is important to balance the electron and hole currents. Rigid-rod polyfluorene has a tendency toward a nematic type of packing arrangement in the bulk, and thus is inherently prone to chain aggregation that leads to a red-shifted emission [9] and to a reduction of emission efficiency [10] . Introduction of kink linkages to the polymer main chain is a widely accepted way to gain control of conjugated length and blue light emission [11,12] . Different kinds of disorder units are introduced to polyfluorene conjugated system, such as carbazole [13] , end-capping [14] , polyphenylene dendrimer substituents [15] , distyrylbenzene [16] , 5,7-dihydrodibenzo-oxepin and dibenzo-thiepine [17] . The resulted copolymers exhibit better spectral properties than fluorene homopolymer. Polypyridine (PPy), with electron-accepting imine structure, is both luminescent and oxidative stable, thus attracting interest in potentially useful material in electronic and photonic devices. It has, for example, been employed with some success as an electron transport layer within polymer light-emitting diodes, affording improved device efficiencies [18] . Synthesis of alternating pyridine-based backbone copolymers with substituted phenylene [19,20] and fluorene units [21] have been reported for tunability of electronic properties with enhanced stability. Recently, Tammer and coworkers reported synthesis and characterization of random copolymers of ‘ para ’ poly(2,5-pyridinediyl) and ‘ meta ’ poly(2,6-pyridinediyl) and demonstrated possibility of control the chain rigidity and the effective conjugation length by the variation of the ratio of ‘ para ’ to ‘ meta ’ [22] . In this paper, the meta pyridine linkage, as the π-accepting moiety, has first been introduced into poly(2,7-(9,9-dioctyl)fluorene). We intend to introduce a ‘kink’ disorder on the conjugated main chain to depress the aggregation phenomenon and to enhance the color purity in blue-emitting polyfluorene. Different pyridine unit ratios in the polymer composition are incorporated to study the trend of the properties. The schematic illustration for this strategy is shown in Scheme 1 . 2 Experiments 2.1 Instrumentation 1 H and 13 C NMR spectra were recorded on Bruker DRX-400 NMR Instrument in deuterated chloroform solution at 25 °C. The molecular weight of the polymers was determined by Waters GPC 2410 in THF via a calibration curve of polystyrene standards. Elemental analysis was performed on Vario EL Elemental Analysis Instrument (Elementar Co.). Thermogravimetric analysis(TGA) measurements were performed on Netzsch TG 209 under N 2 at a heating rate of 20 °C/min. Differential scanning calorimetry (DSC) measurements were performed on Netzsch DSC 204 under N 2 at a heating rate of 10 °C/min. Cyclic voltammetry (CV) was recorded on a computer-controlled CHI660A electrochemical workstation. A glass–carbon electrode (∼0.1 cm 2 ) was coated with a thin film from chloroform solution of polymers and used as the working electrode. A platinum wire was used as the counter electrode and an Ag/AgCl electrode used as the reference electrode at a scan rate of 50 mV/s in a nitrogen-saturated solution of 0.1 M tetrabutylammonium hexafluorophosphate (Bu 4 NPF 6 ) in acetonitrile (CH 3 CN). UV–vis absorption spectra were recorded on a HP 8453 spectrometer. PL quantum yields were determined in integrating sphere IS080 with 325 nm excitation of He–Cd laser (Mells Griod) or with 405 nm of solid state laser (Crystal Laser). EL efficiencies were achieved with calibrated silicon photodiode. PL and EL spectra were recorded by using Instaspec 4 CCD spectrophotometer (Oriel Co.). The surface morphology was investigated using tapping-mode atomic force microscopy (AFM) (Thermo. Auto Probe C P Res.). AFM images of the films (100-nm-thick layer) spun from a toluene solution of polymers at 2000 rpm on indium tin oxide (ITO) substrates coated with a 30-nm-thick layer of poly (ethylene dioxythiophene) doped with polystyrene sulfonic acid (PEDOT:PSS). 2.2 Materials Fluorene, n -butyllithium, n -octylbromide, 2-isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, 3,5-dibromopyridine and tetraethylammonium hydroxide were purchased from Aldrich Co. Tetrakis(triphenylphosphine) palladium was obtained from TCI Co. Anhydrous tetrahydrofuran was distilled over sodium/benzophenone under nitrogen prior to use. Chloroform and toluene were distilled over calcium chloride. 9,9-Dioctylfluorene (1) and 2,7-dibromo-9,9-dioctylfluorene (2) were prepared according to the published procedures [23] . 2,7-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-9,9-dioctylfluorene (3) [21] . n -Butyllithium (19.7 ml of a 1.6 M solution in hexane, 31.45 mmol) was dropwise added into a solution of 2,7-dibromo-9,9-dioctylfluorene (2) (5.6 g, 10.22 mmol) in THF (130 ml) at −78 °C. The mixture was stirred at −78 °C for 2 h, 2-isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (25 ml, 123.24 mmol) was added rapidly to the solution, and the mixture was stirred at −78 °C for 2 h. Then the mixture was warmed up to a room temperature and stirred for another 36 h. The mixture was poured into water and was extracted with ether. The organic layer was washed with brine and dried over an anhydrous magnesium sulfate. The solvent was removed under a reduced pressure. The crude product was purified by column chromatography (silical gel, 10% ethyl acetate in hexane) to make the product shown in the title as a white solid, (Mp=128–131 °C) in 46% yield. 1 H NMR (500 MHz, CDCl 3 , ppm): 7.81 (d, 2H), 7.74 (s, 2H), 7.71 (d, 2H), 1.99 (m, 4H), 1.39 (s, 24H), 1.22–1.00 (m, 20H), 0.81 (t, 6H), 0.56 (m, 4H); 13 C NMR (100 MHz, CDCl 3 , ppm): 150.86, 144.30, 134.04, 129.29, 119.77, 84.11, 55.57, 40.49, 32.18, 30.33, 29.58, 25.33, 23.98, 22.99, 14.48. Element Anal. Calcd for C 41 H 64 O 4 B 2 : C, 76.74%, H, 10.04%. Found: C, 76.44%; H, 9.90%. 2.3 Polymer synthesis [24] Carefully purified 2,7-dibromo-9,9-dioctylfluorene, 2,7-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-9,9-dioctylfluorene, 3,5-dibromo-pyridine and (PPh 3 ) 4 Pd(0) (0.5–1.5 mol%) were dissolved in a mixture of toluene and (C 2 H 5 ) 4 NOH (20%) aqueous solution. Under argon atmosphere the solution was refluxed by vigorous stirring for 48 h. The whole mixture was poured into methanol. The precipitated material was recovered by filtration through a funnel and washed with acetone to remove oligomers and catalyst residues. Seven copolymers with different compositions were synthesized from various starting molar ratios of DOF to Py: 99:1, 95:5, 90:10, 80:20, 70:30, 60:40 and 50:50. The isolated copolymers were obtained in 70–80% yield. The resulted polymers were soluble in common organic solvents (chloroform or tetrahydrofuran). 1 H NMR (500 MHz, CDCl 3 , ppm): with PFPy50: 8.29 (2H), 8.26 (1H), 7.95 (2H), 7.90 (2H), 7.84 (2H), 2.22 (4H),1.14 (24H) and 0.79 (6H); 13 C NMR (100 MHz, CDCl 3 , ppm): 156.92, 152.29, 142.15, 138.76, 137.85, 126.54, 121.83, 120.66, 118.96, 55.80, 41.02, 32.24, 30.62, 29.74, 24.36, 22.94 and 14.38. The results of elemental analyses of nitrogen and carbon for each copolymer were used for calculation of actual copolymer composition. Element Anal. Found: for PFPy5: C, 88.74%; N, 0.21%; for PFPy10: C, 82.25%; N,0.30%; for PFPy20: C, 88.56%; N, 0.59%; for PFPy30: C, 88.32%; N, 1.07%; for PFPy50: C, 86.92%; N, 2.78%. 3 Results and discussion 3.1 Synthesis and characterization of copolymers Various high molecular weight, readily soluble copolymers from 2,7-dibromo-9,9-dioctylfluorene, 2,7-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-9,9-dioctylfluorene and comonomer 3,5-dibromo-pyridine were prepared by using palladium catalyzed Suzuki polycondensation ( Scheme 1 ). The comonomer feed ratios of DOF to Py are 99:1, 95:5, 90:10, 80:20, 70:30, 60:40 and 50:50 and the corresponding copolymers are named PFPy1, PFPy5, PFPy10, PFPy20, PFPy30, PFPy40 and PFPy50, respectively. The starting monomer ratios have been adjusted in order to investigate the effect of copolymer composition on the physical and optical properties. The actual ratio of DOF to Py in the copolymer calculated from elemental analysis is close to the feed ratio as listed in Table 1 . When the concentration of Py in the copolymers is less than 50 mol%, the resulted polymers are kinds of special random copolymers that consist of the fluorene segment of different lengths separated by a single pyridine unit from both sides of each segment. When the concentration of pyridine is equal to 50 mol%, the copolymer has a regular alternating A–B structure. Copolymers obtained are of relatively high molecular weight with a polydispersity index ( M w / M n ) from 1.2 to 2.5 ( Table 1 ). The random copolymers have higher molecular weights than the alternating copolymer. The thermal properties of polymers are evaluated by TGA and DSC measurement. TGA reveals excellent thermal stabilities of homo- and co-polymers under nitrogen. As shown in Table 1 , the decomposition temperature (5% weight loss) is 385 °C for homopolymer and about 400 °C for copolymers. Thermally induced phase transition behavior of polymers is investigated by DSC. The glass transition temperatures ( T g ) of polymers slightly rise from 70 to 93 °C with the increase of Py content. This indicates that the interchain interaction increases in the copolymers. The phase transition temperature from partially crystalline state to liquid crystalline ( T Cr–LC ) of PDOF is 155 °C. The T Cr–LC values of copolymers are much less than that of homopolymer ( Table 1 ), due to the decrease of chain regularity by the meta -linkage along the polymer backbone. 3.2 Optical properties The optical characteristics of polymers are investigated both in solution and in solid state. The absorption and emission spectral data for polymers are summarized in Table 2 . UV–vis absorption spectra in diluted CHCl 3 solution of copolymers are depicted in Fig. 1(a) . The spectra reveal a general trend of slightly increased blue-shift of λ max with the increase of meta -pyridine content. The blue-shift is consistent with the reduction in π-conjugation induced by the introduction of the 3,5-pyridinediyl moieties. For fluorene homopolymer in thin film, the absorption spectrum is consistent with that reported previously [25] . Absorption profile is featured with a main peak at ca. 380 nm and a small sharp shoulder at 430 nm ( Fig. 1(b) ), the latter is interpreted as an evidence of β-phase formation in the glass phase of PDOF [18] . This interpretation is supported by the fact that 430 nm feature disappears in the solution spectrum ( Fig. 1(a) ). It is important to note that the intensity of 430 nm peak decreases substantially with incorporation of 5–10 mol% pyridine unit into polyfluorene backbone ( Fig. 1(b) ). This peak completely disappears once the pyridine content increases to ca. 20 mol% in the copolymers, which indicates that the incorporation of 3,5-linkage pyridine unit into polyfluorene chain really introduces the disorder in polymer backbone, as a result of which β-phase formation becomes impossible in the glass phase [26] . The optical band gaps ( E g ) of polymers are 2.76–3.15 eV from the onset in the film absorption spectra. The absorption wavelengths of copolymers are blue-shifted with the increase of pyridine concentration. Among them the alternating copolymer shows the largest blue-shift ( Δ λ=40 nm ) in absorption spectra and the greatest increase in E g ( Table 2 ). The observed blue-shift suggests that the 3,5-pyridinediyl effectively decreases the conjugation length of polymer backbone, since the linear π-system is interrupted [27] . Photoluminescent (PL) spectra of copolymers shown in Fig. 2 reveal a similar trend, PL peaks being slightly blue-shifted with increasing the pyridine contents for random copolymers. In consistence with the absorption spectra, the alternating copolymer shows the largest blue-shift compared with others. The observed blue-shift in PL spectra is a further evidence of the reduced conjugation along the polymer backbone. PL efficiencies of copolymer films are listed in Table 2 . The PL efficiency shows the maximum at pyridine content of around 30 mol% in the copolymers. With further increase of meta -linkage contents, the PL efficiency decreases rapidly to 15% for alternating copolymer. Such PL efficiency dependence is reproducible during repeating measurements. It is no clear that the origin of such complicated behavior of PL efficiencies vs. 3,5-pyridine contents. We note that similar transition point at around 35% was reported by Tammer et al. [22] for random copolymers of ‘ para ’ poly(2,5-pyrinediyl) and ‘ meta ’ poly(2,6-pyrinediyl) (PPY-PmPY).They observed that PL emission peaks for copolymers with meta -linkage in composition between 0–35% are almost constant, peaked at around 535 nm as for ‘ para ’ PPY homopolymer, while significantly blue-shifted with further increase of ‘ meta ’ contents. They explained the observed phenomena by that at levels below 35%, the meta links gradually lose the chain rigidity, but at high levels (>35%) of the meta links reduce the effective conjugation length of the copolymers. 3.3 Electrochemical properties The redox behavior of polymers is investigated by CV. As shown by the cyclic voltammograms in Fig. 3 , the polymers exhibit partial reversibility in both n-doping and p-doping processes. The oxidation and reduction potentials derived from the onset of the electrochemical p-doping and n-doping are summarized in Table 3 . HOMO and LUMO levels are calculated according to an empirical formula ( E HOMO =− e ( E ox +4.4) (eV) and E LUMO =− e ( E red +4.4) (eV)) [28] . As shown in Table 2 , HOMO and LUMO levels of the fluorene homopolymer are 5.77 and 2.16 eV, respectively. With the increase of pyridine contents, the oxidation potentials are almost unchanged up to the pyridine content of 40 mol% and the reduction potentials increase slightly. However, the alternating copolymer exhibits both the lower oxidation potential (by 0.41 V) and the higher reduction potential (by 0.17 V) compared with fluorene homopolymer. Moderate increase of LUMO levels of copolymers with increasing pyridine contents can be attributed to the increase of electron-withdrawing pyridinyl moieties in polymer backbone. We could expect the improvement in electron injection from the cathode in comparison with fluorene homopolymer. From Table 3 , it can be seen that the energy gaps ( E ′ g ) between E (oxidation) and E (reduction), which are determined by CV, decrease as the pyridine contents of copolymers increase although the optical band-gaps increase ( Table 2 ). This differences may be caused by the interface barriers between the polymer films and the electrode surfaces [29] . The electrochemical datum may be the combination of the optical band-gap and the interface barrier for charge injection that makes it larger [30] . Seki et al. [31] and Park et al. [32] investigated the interfaces between metals (Ca, Al) and organic emitting layers (PPV oligomer, Alq 3 ) and found the existence of an electric dipole layer at the interface and defined the potential differences between the outermost electrode surface and the first polymer layer as Δ . The formation of the interfacial dipole layer can modify the barrier height by the value of Δ . The general tendency of the direction and magnitude of Δ gives a guide line for applying the traditional method to the estimation of the barrier heights [31] . As for this system, there should be a hydrogen bond interaction between pyridine group and Si–O–H hydrogen atom on the surface of the glass–carbon electrode. Thus, N-containing polymer chains can be aligned in parallel with the surface of a glass–carbon electrode [33] . In opposition to the optical band-gap, therefore, the barrier height might decrease with the increases of pyridine contents. As the effects of pyridine contents on the barrier height—both the direction and magnitude—overwhelm that on the optical band-gap, E ′ g s decrease with the increase of pyridine contents. 3.4 Electroluminescent properties Fig. 4 shows the EL spectra of the homo-polymer and copolymers. Device configuration is as follows: ITO/PEDOT:PSS/polymer/Ba/Al. PEDOT is used as an anode buffer, and Ba is used as a cathode. As shown in Fig. 4 , the intensity of excimer emission in visible region decreases with the increase of pyridine contents. Pure and narrow emission appears for the copolymer with 40 mol% pyridine content. As expected, a significant excimer emission appears for the alternating copolymer due to the high regularity of polymer chain. The results indicate that the introduction of meta -linkage pyridine in a certain comonomer ratio into polyfluorene backbone is effective in depression of excimer emission from Table 4 . Except the alternating copolymer, the EL external quantum efficiencies of copolymers are very close, despite the fact that LUMO levels of copolymers increase with the increase of pyridine contents. The alternating copolymer shows a significant lower efficiency despite the observable decrease in its HOMO level ( Table 3 ). These facts indicate that the device performances are controlled by carrier mobility rather than by electron and hole injection. Further evidence for this argument can be obtained from Table 5 , where we compare device performances with the different anode buffers and cathodes. As can be seen from Table 5 , no substantial improvements in device efficiencies are observed when PEDOT-PSS with work function of 5.0 eV [34] is replaced by PVK with work function of 5.8 eV [35,36] , which matches HOMO level of PFPy copolymers ( Table 3 ). Quantum efficiency could be evidently improved by replacing PEDOT-PSS with PVK buffer layer if the device efficiency is hole-injection limited. On the other hand, since device efficiencies are not improved with the increases of LUMO levels, the device efficiencies for such copolymers seem to be limited by low carrier mobility, which is the result of breaking π-conjugation by the introduction of meta -linkage of pyridine sites. Direct measurement of carrier (electron or hole) mobility for copolymers with different pyridine contents can provide the better understanding of structure-property relations in this interesting system. Since film morphology is also important for device performances, the film surfaces are inspected by AFM. Fig. 5 illustrates AFM studies of the surfaces of fluorene homopolymer (a) and copolymer films (b, c) on ITO substrates. The copolymer films show the fine-scale phase separation in the range of 5–10 nm and have a root-mean-square (rms) roughness of about 0.5 nm. In contrast, the homopolymer exhibits large-scale phase separation in the diameter of 30–40 nm and has a rms roughness of 1.4 nm. Based on above results, the device performances could be further explained. Jakubiak et al. [37] reported that the aggregation of polymer chains enhances the excimer formation, which reduces the PL quantium efficiency. The films spun from different solvents also show different PL spectra. This observation suggests that the morphology of polymer has a remarkable effect on its emission spectrum [38] . The aggregate formation is found to be morphology dependent. The film from a good solvent leads to better interchain registry than from a poor solvent [39] . Toluene is a better solvent for homopolymer than for copolymers. We therefore, suggest the following origin for the morphology dependence of aggregation: homopolymer film from toluene in which the polymer is much better soluble, leading to a more planar and extended conformation [40] . As a result, homopolymer forms a big aggregation ( Fig. 5(a) ). On the other hand, copolymers are less soluble in toluene, leading to a disordered coil-like conformation, and form a small aggregation [41] ( Fig. 5(b) and (c) ). The formation of aggregates is apparently detrimental to PL efficiency and leads to the red-shifted film spectra. That could explain why the device of homopolymer has an apparent red-shift emission as well as the device of copolymer (PFPy40) has a pure emission spectrum and a moderately high emission efficiency. As to the alternating copolymer, the apparent red-shift emission can't be explained only from the AFM morphological point of view. Considering there are large differences in molecular weight as well as in polydispersity index between homopolymer and copolymers, corresponding studies in this direction are in progress. 4 Conclusions High molecular weight, readily soluble copolymers of 9,9-dioctylfluorene with pyridine (less than or equal to 50 mol%) are synthesized by Suzuki polycondensation. The introduction of pyridine unit at 3,5-position into polyfluorene backbone significantly depresses the excimer formation. The intensity of excimer emission decreases with the increases of pyridine contents. Narrow and pure blue EL emission is obtained for copolymer with the pyridine content of 40 mol%. External quantum efficiency is moderately high (0.4–0.5%) for such pure blue emitter. Device efficiency seems to be limited by low carrier mobility, which is the result of breaking π-conjugation by introduction of meta -linkage of pyridine sites. Acknowledgements This work is supported by MOST (Project No. 2002CB6613402), the National Natural Science Foundation of China (No. 50173008) and the Natural Science Foundation of Guang-dong Province (No. 011545). References [1] G. Gustafsson Y. Cao G.M. Treacy F. Klavertter N. Colaneri A.J. Heeger Nature 357 1992 477 [2] J.H. Burroughes D.D.C. Bradly A.R. Brown R.N. Marks K. Markay R.H. Friend B. Burns A.B. Holmes Nature 347 1990 539 [3] G. Grem G. Ledizky B. Ullrich G. Leising Adv Mater 4 1992 36 [4] Y. Yang Q. Pei A.J. Heeger J Appl Phys 79 1996 934 [5] M. Berggren O. Inganas G. Gustafsson M.R. Andersson T. Hjertberg O. 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Bradley M. Grell C. Giebeler M. Inbasekaran E.P. Woo Appl Phys Lett 73 17 1998 2453 [30] Z.K. Chen W. Huang L.-H. Wang E.T. Kang B.J. Chen C.S. Lee S.T. Lee Macromolecules 33 2000 9015 [31] H. Ishii K. Sugiyama D. Yoshimura E. Ito Y. Ouchi K. Seki IEEE J Sel Top Quantum Electron 4 1998 24 [32] Y. Park V. Choong E. Ettendgui Y. Gao B.R. Hsieh T. Wehrmeister K. Mullen Appl Phys Lett 69 1996 1080 [33] T. Yamamoto Macromol Rapid Commun 23 2002 583 [34] Y. Cao G. Yu C. Zhang R. Menon A.J. Heeger Synth Met 87 1997 171 [35] J. Kido K. Hongawa K. Okuyama K. Nagai Appl Phys Lett 64 1994 815 [36] B. Layla T.V. Francois S. Olivier Synth Met 122 2001 351 [37] R. Jakubiak C.J. Collion W.C. Wan L.J. Rothberg B.R. Hsieh J Phys Chem B 103 1999 2394 [38] J.W. Blatchford T.L. Gustafson A.J. Epstein D.A. Vanden Bout J. Kerimo D.A. Higgins P.F. Barbarar D.-K. Fu T.M. Swager A.G. MacDiarmind Phys Rev B 54 6 1996 3683 [39] M.A. Diaz-Garcia F. Hide B.J. Schwartz M.R. Andersson Q. Pei A.J. Heeger Synth Met 84 1997 455 [40] Y. Shi J. Liu Y.J. Yang Appl Phys 87 9 2000 4254 [41] J.W. Blatchford S.W. Jessen L.-B. Lin T.L. Gustafson D.-K. Fu H.-L. Wang T.M. Swager A.G. MacDiarmind A.J. Epstein Phys Rev B 54 13 1996 9180",
        "keywords": [
            "blue-emitting copolymer",
            "color purity",
            "fluorene",
            "electroluminescence",
            "threshold voltage",
            "external quantum efficiency"
        ],
        "authors": [
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Jian Huang",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology, Wushan road, Guangzhou 510640, China"
            },
            {
                "name": "Chuanzhen Liu",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology, Wushan road, Guangzhou 510640, China"
            },
            {
                "name": "Yuhua Niu",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology, Wushan road, Guangzhou 510640, China"
            },
            {
                "name": "Qiong Hou",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology, Wushan road, Guangzhou 510640, China"
            },
            {
                "name": "Renqiang Yang",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology, Wushan road, Guangzhou 510640, China"
            },
            {
                "name": "Yong Cao",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology, Wushan road, Guangzhou 510640, China"
            }
        ],
        "venue": "Polymer",
        "year": 2004
    },
    "s4VFvBla": {
        "id": "s4VFvBla",
        "title": "Synthesis and Characterization of Polyfluorene electrolytes as Green and Red Light-emitting Layers for High-Efficiency PLEDs",
        "abstract": "A series of ammonium-ended alkyl-substituted polyfluorene copolymer with narrow band-gap comonomer benzothiadiazole (BTDZ) and 4,7-di-2-thienyl-2,1,3-benzothiadiazole (DBT) were synthesized of by Suzuki polycondensation. The resulting polymers can be processed as an RGB active layer in polymer light emitting devices from environment friendly solvents such as alcohols. It is found out that devices from such polymers show equal or higher external quantum efficiencies (QE) with the high work-function metal cathode such as Al than by using the low work-function (Ca or Ba) cathode. The added BTDZ and DBT units not only change the polymers’ emission color, but also greatly improved the device performances of the polymers, as a result of the suppression of excimer formation which is common to rigid polyelectrolyte chains.",
        "keywords": [
            "light-emitting diode",
            "conjugated polymers",
            "polyfluorene",
            "polyelectrolytes",
            "external quantum efficiency",
            "band gap",
            "work function",
            "light emitting diode"
        ],
        "authors": [
            {
                "name": "Huilin Shen",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Laboratory of Specially Functional Materials and Advanced Manufacturing Technology, South China University of Technology, Guangzhou 510640, China"
            },
            {
                "name": "Fei Huang",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Laboratory of Specially Functional Materials and Advanced Manufacturing Technology, South China University of Technology, Guangzhou 510640, China"
            },
            {
                "name": "Lintao Hou",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Laboratory of Specially Functional Materials and Advanced Manufacturing Technology, South China University of Technology, Guangzhou 510640, China"
            },
            {
                "name": "Hongbin Wu",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Laboratory of Specially Functional Materials and Advanced Manufacturing Technology, South China University of Technology, Guangzhou 510640, China"
            },
            {
                "name": "Wei Cao",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Laboratory of Specially Functional Materials and Advanced Manufacturing Technology, South China University of Technology, Guangzhou 510640, China"
            },
            {
                "name": "Wei Yang",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Laboratory of Specially Functional Materials and Advanced Manufacturing Technology, South China University of Technology, Guangzhou 510640, China"
            },
            {
                "name": "Yong Cao",
                "org": ""
            }
        ],
        "venue": "Synthetic Metals",
        "year": 2005
    },
    "w7QAZBGx": {
        "id": "w7QAZBGx",
        "title": "Synthesis and properties of novel poly(p-phenylenevinylene) copolymers for near-infrared emitting diodes",
        "abstract": "A series of novel near-infrared (NIR) electroluminescence (EL) copolymers based on a host poly( p -phenylenevinylene) (PPV) derivative of poly(2-methoxy-5-octyloxy- p -phenylenevinylene) (PMOPV) with different content of narrow band-gap (NBG) unit 4,7-bis(2-thienyl)-2,1,3-benzothiadiazolevinylene (DBTV) or 4,7-bis(2-thienyl)-2,1,3-benzoselenadiazolevinylene (TBSV) was prepared by Stille coupling reaction. All the copolymers are soluble in common organic solvents, most of which emit NIR light accompanied by gradually red-shifting with increasing the content of the NBG units. The peak EL emission of the copolymers with around 30% TBSV content is at about 800 nm.",
        "keywords": [
            "polymer light-emitting diodes (pleds)",
            "narrow band-gap (nbg)",
            "poly( p -phenylenevinylene)",
            "stille coupling reaction",
            "near-infrared emitting diodes",
            "light emitting diode",
            "near infrared",
            "band gap",
            "electroluminescence"
        ],
        "authors": [
            {
                "name": "Xianzhen Li",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Laboratory of Special Functional Materials and Advanced Manufacturing Technology, South China University of Technology, Guangzhou 510640, PR China"
            },
            {
                "name": "Wenjin Zeng",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Laboratory of Special Functional Materials and Advanced Manufacturing Technology, South China University of Technology, Guangzhou 510640, PR China"
            },
            {
                "name": "Yong Zhang",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Laboratory of Special Functional Materials and Advanced Manufacturing Technology, South China University of Technology, Guangzhou 510640, PR China"
            },
            {
                "name": "Qiong Hou",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Laboratory of Special Functional Materials and Advanced Manufacturing Technology, South China University of Technology, Guangzhou 510640, PR China"
            },
            {
                "name": "Wei Yang",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Laboratory of Special Functional Materials and Advanced Manufacturing Technology, South China University of Technology, Guangzhou 510640, PR China"
            },
            {
                "name": "Yong Cao",
                "org": ""
            }
        ],
        "venue": "European Polymer Journal",
        "year": 2005
    },
    "vZiQBp2P": {
        "id": "vZiQBp2P",
        "title": "Synthesis and properties of a novel water-soluble anionic polyfluorenes for highly sensitive biosensors",
        "abstract": "A new anionic water-soluble polyfluorene—poly(9,9-bis(4′-sulfonatobutyl)fluorene- co - alt -1,4-phenylene) sodium salt (PFS) was synthesized by Suzuki-coupling reaction. The anionic polyfluorene shows bright blue photoluminescence and it was found the photoluminescence could be highly quenched by a bioactive dye (Lucifer yellow cadaverine biotin-X dipotassium salt). PFS photoluminescence quenching only occurs effectively upon addition of avidin. The photoluminescence quenching process is sensitive to even subnanomolar amount of avidin (10 −10 M). The avidin facilitated photoluminescence quenching opens up opportunities of new ultra-high efficiency and rapid response biosensors based on the polyfluorene electrolyte.",
        "keywords": [
            "biosensor",
            "water-soluble",
            "polyelectrolyte",
            "water soluble"
        ],
        "authors": [
            {
                "name": "Fei Huang",
                "org": "Key Laboratory of Specially Functional Materials and Advanced Manufacturing Technology, Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology, Guangzhou 510640, China"
            },
            {
                "name": "Xiaohui Wang",
                "org": ""
            },
            {
                "name": "Deli Wang",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": "Key Laboratory of Specially Functional Materials and Advanced Manufacturing Technology, Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology, Guangzhou 510640, China"
            },
            {
                "name": "Yong Cao",
                "org": ""
            }
        ],
        "venue": "Polymer",
        "year": 2005
    },
    "JCA9KfsI": {
        "id": "JCA9KfsI",
        "title": "Efficient electron injection from bilayer cathode consisting of aluminum and alcohol/water-soluble conjugated polymers",
        "abstract": "",
        "keywords": [
            "Aminoalkyl-substituted polyfluorene copolymer",
            "Electroluminescent",
            "Electron injection",
            "Metal/semiconductor interface",
            "Polymer light-emitting diodes"
        ],
        "authors": [
            {
                "name": "Hongbin Wu",
                "org": ""
            },
            {
                "name": "Fei Huang",
                "org": ""
            },
            {
                "name": "Yueqi Mo",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Junbiao Peng",
                "org": ""
            },
            {
                "name": "Yong Cao",
                "org": ""
            }
        ],
        "venue": "Journal of The Society for Information Display",
        "year": 2005
    },
    "kmZhmblZ": {
        "id": "kmZhmblZ",
        "title": "Efficient white-light-emitting diodes based on polymer codoped with two phosphorescent dyes",
        "abstract": "",
        "keywords": [
            "indium tin oxide",
            "spectrum",
            "electroluminescence",
            "organic material"
        ],
        "authors": [
            {
                "name": "yunhua xu",
                "org": "south china university of technology"
            },
            {
                "name": "junbiao peng",
                "org": "south china university of technology"
            },
            {
                "name": "jiaxing jiang",
                "org": "south china university of technology"
            },
            {
                "name": "wei xu",
                "org": "south china university of technology"
            },
            {
                "name": "wei yang",
                "org": "south china university of technology"
            },
            {
                "name": "yong cao",
                "org": "south china university of technology"
            }
        ],
        "venue": "Applied Physics Letters",
        "year": 2005
    },
    "WDFoNeHo": {
        "id": "WDFoNeHo",
        "title": "High-Efficiency Electrophosphorescent Fluorene-<i>alt</i>-carbazole Copolymers N-Grafted with Cyclometalated Ir Complexes",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Jiaxing Jiang",
                "org": ""
            },
            {
                "name": "Changyun Jiang",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Hongyu Zhen",
                "org": ""
            },
            {
                "name": "Fei Huang",
                "org": ""
            },
            {
                "name": "Yong Cao",
                "org": ""
            }
        ],
        "venue": "Macromolecules",
        "year": 2005
    },
    "rpVcM9Ea": {
        "id": "rpVcM9Ea",
        "title": "Deep-red electroluminescent polymers: Synthesis and characterization of new low-band-gap conjugated copolymers for light-emitting diodes and photovoltaic devices",
        "abstract": "A novel series of semiconducting conjugated copolymers, derived from alkyl-substituted fluorene, 4,7-diselenophen-2′-yl-2,1,3-benzothiadiazole (SeBT), and 4,7-diselenophen-2′-yl-2,1,3-benzoselenadiazole (SeBSe), was synthesized by a palladium-catalyzed Suzuki coupling reaction with various feed ratios. The optical band gap of copolymers is very low, 1.87 eV for SeBT and 1.77 eV for SeBSe. The efficient fast energy transfer from fluorene segments to narrow-band-gap sites was observed. The emission of photoluminescence and electroluminescence is dominated by narrow-band-gap species and peaked at 670-790 nm, in the range from deep-red to near-infrared (NIR). The external electroluminescent (EL) quantum efficiencies reached 1.1% and 0.3% for devices from these two types of copolymers, respectively. Bulk-heterojunction polymer photovoltaic cells (PPVCs) made from composite thin film of the copolymer 9,9-dioctylfluorene and SeBT (PFO-SeBT) in blend with fullerene derivative [6,6]-phenyl C61 butyric acid methyl ester (PCBM) as an active layer show promising performances. The energy conversion efficiency (ECE) is up to 1% under AM1.5 solar simulator (78.2 mW/cm2). The spectral response is extended up to 675 and 750 nm for PPVCs from PFO-SeBT and PFO-SeBSe, respectively.",
        "keywords": [
            "band gap",
            "light emitting diode",
            "electroluminescence"
        ],
        "authors": [
            {
                "name": "Renqiang Yang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Renyu Tian",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Jing'ai Yan",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Yong Zhang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Jian Yang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Qiong Hou",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Wei Yang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Chi Zhang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Yong Cao",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            }
        ],
        "venue": "Macromolecules",
        "year": 2005
    },
    "Ll8GY8vH": {
        "id": "Ll8GY8vH",
        "title": "Synthesis and electrophosphorescent performances of alkyl-substituted bicycloiridium complexes in polymer light-emitting diodes",
        "abstract": "In this paper, two complexes (mppy) 2 Ir(tmd) and (bppy) 2 Ir(tmd) were synthesized and doped into PVK. We find that the alkyl substitution of bicycloiridium complexes on acetylacetonate ligand has a great effect on optimizing the PLED performances. The best device performance is observed for the (bppy) 2 Ir(tmd)-doped PVK–PBD (40 wt%) device with the concentration of 1 wt%. A maximal external quantum efficiency of QE ext = 14.2% ph/el and the luminous efficiency of LE = 33 cd/A with a luminance of 2099 mA/cm 2 were achieved at a current density of 6.4 mA/cm 2 . Keywords Alkyl substitution Bicycloiridium complex PVK Doping PLED 1 Introduction Recently, high-efficiency OLEDs, which are made of phosphorescent materials and in which the singlet and triplet excitons of the molecules contribute to light generation, have been demonstrated [1,2] . Iridium-based complexes are the popular choice for the triplet emissive centers because of the short triplet lifetime and high-light emission efficiency [3–6] . Compared with tricycloiridium complexes, bicycloiridium complexes are easy to be synthesized because of the moderate reaction condition and high yield. The bicycloiridium complexes were widely applied to O/PLED with different colors and high efficiency. The green OLEDs with bis-(2-phenylpyridine)iridium(III) acetylacetonate [(ppy) 2 Ir(acac)] doped into 3-phenyl-4-(1′-naphthyl)-5-phenyl-1,2,4-triazole (TAZ) shows a high external quantum efficiency of 19% ph/el and a power efficiency of 60 lm/W [7] . Jiang et al. [8] achieved an external quantum efficiency of 12% ph/el and a luminous efficiency of 5.2 cd/A, with the maximum emission at 624 nm by doping iridium(III)bis-[(1-phenylisoquinolyl)- N ,C 2′ ] acetylactonate [(piq) 2 Ir(acac)] into conjugated poly(9,9-dioctylfluorene) (PFO) and 2-(4-biphenyl)-5-(4- tert -butylphenyl)-1,3,4-oxadiazole (PBD). By changing the position of substitution, the peaks of EL spectra were tuned in the wavelength region from 513 to 578 nm. The external quantum efficiencies of 10–17% were achieved by doping perfluorophenyl-substituted complexes into 4,4′-di(carbazole-9-yl)-biphenyl (CBD) [9] . The blue OLEDs with bis[(4,6-difluoro-phenyl)-pyridinato- N ,C 2′ ](picolinato)[Ir(FIrpic)] doped into N , N -dicarbazolyl-1,4-dimethene-benzene (DCB) exhibits a maximal external efficiency and a luminous efficiency of 5.8% and 9.8 cd/A, respectively, at a luminance of 22 cd/m 2 driven at the voltage of 6.0 V [10] . It is of great benefit to use polymers as host materials for phosphorescent guest since PLEDs have the potentials to be used for large-size displays, thus leading to a simple process and lower cost. Because of the imcompatibility between complex and polymer host, the design of the complex structure is very important to decrease the phase segregation [11] . There are extensive researches on the investigation of luminescent properties of bicycloiridium complexes containing two ortho -chelating (C^N) ligands and a bidentate ancillary ligand and their use and performance as triplet emitters in EL devices in the past few years, but the illustration of the effect of substituents, such as simple functional groups, and the dependence on their positions upon the phenyl or pyridine rings in the ppy backbone were not widely investigated especially for the substituent on the bidentate ancillary ligand [12–15] . In this paper, we synthesized two novel alkyl-substituted complexes and doped them in PVK host polymer, finding that the alkyl substitution on the bidentate ligand of the bicycloiridium complexes also has a great effect on optimizing LED performances. 2 Experiments 2.1 Measurements 1 H NMR spectra were recorded on a Bruker DRX 400 spectrometer operating at 400 MHz and in deuterated chloroform solution with tetramethylsilane as a reference. Elemental analyses were performed on Vario EL Elemental Analysis Instrument (Elementar Co.). UV–vis absorption spectra were recorded on a HP 8453 UV–vis spectrophotometer. Cyclic voltammetry were carried out on a Potentiostat/Galvanostat Model 283 (Princeton Applied Research) with platinum electrode at a scan rate of 50 mV/s against a calomel reference electrode in a nitrogen-saturated complex CH 2 Cl 2 solution of tetrabutylammonium hexafluorophosphate (Bu 4 NPF 6 ) (0.1 M). PL spectra of the complexes solution were obtained on a Fluorolog-3 Spectrometer (Jobin-Yvon) with 90° angle detection. PL spectra of the complexes-doped PVK in thin film on quartz substrate was recorded on an Instaspec IV CCD spectrophotometer (Oriel Co.) under excitation from the 325 nm line of a HeCd laser. 2.2 Materials Poly (9-vinyl carbazole) (PVK) was purchased from Aldrich Co. having a weight-average molecular weight of 1,100,000. All manipulations involving air-sensitive reagents were performed in the atmosphere of dry nitrogen. All reagents, unless otherwise specified, were obtained from Acros and TCI Chemical Co., and were used as received. 2.2.1 General preparation of alkylsubstituted iridium complexes, taking iridium(III)-bis(2-p-tolylpyridine-C 2′ , N )acetylacetonate [(mppy) 2 Ir(acac)] as an example The corresponding complexes were prepared according to the published procedures [16] . Iridium trichloride hydrate (178 mg, 0.56 mmol), 2-p-tolyl-pyridine (284 mg, 1.68 mmol), 2-ethoxyethanol (10 ml) and water (5 ml) were added into a three-neck flask (100 ml). The mixture was refluxed under the argon atmosphere for 24 h and then cooled down to room temperature. A yellow precipitate was filtered and washed with water and ethanol several times. The resulted yellow solid was purified by recrystallization in mixture of CH 2 Cl 2 and hexane. Then the dried product (476 mg, 0.078 mmol) was mixed with pentanedione (22 mg, 0.22 mmol) and sodium carbonate (13 mg) in 8 ml of degassed 2-ethoxyethanol in a three-neck flask. The mixture was refluxed in an argon atmosphere for 13 h. After cooling down to room temperature the yellow precipitate was formed. After being filtered and washed with water and methanol, the precipitate was purified by column chromatography (silica gel, dichloromethane) to get the yellow powder product (yield 80%). 1 H NMR (400 MHz; CDCl 3 ) δ (ppm): 8.47 (d, 2H), 7.76 (d, 2H), 7.67 (t, 2H), 7.42 (d, 2H), 7.07 (t, 2H), 6.62 (d, 2H), 6.06 (s, 2H), 5.18 (s, 1H), 2.04 (s, 6H), 1.76 (s, 6H). Element Anal. Calcd. for C 29 H 27 IrN 2 O 2 (%): C, 55.50; H, 4.30; N, 4.47; found (%): C, 55.32; H, 4.48; N, 4.21. Irdium(III)bis(2-p-tolyl-pyridine-C 2′ , N )-2,2,6,6-tetramethyl-3,5-heptanedione[(mppy) 2 Ir(tmd)] 1 H NMR (400 MHz; CDCl 3 ) δ (ppm): 8.34 (d, 2H), 7.75 (d, 2H), 7.65 (t, 2H), 7.42 (d, 2H), 7.10 (t, 2H), 6.60 (d, 2H), 6.16 (s, 2H), 5.44 (s, 1H), 2.06 (s, 6H), 0.87 (s, 18H). Element Anal. Calcd for C 35 H 39 IrN 2 O 2 (%): C, 59.07; H, 5.49; N, 3.94; found (%): C, 58.93; H, 5.58; N, 3.80. 2-(4- tert -Butylphenyl)pyridine was prepared as the published procedure [17] . Iridium(III)bis(2-(4- tert -butylphenyl)pyridine-C 2′ , N )2,2,6,6-tetramethyl-3,5-heptanedione [(bppy) 2 Ir(tmd)] 1 H NMR (400 MHz; CDCl 3 ) δ (ppm): 8.44 (d, 2H), 7.82 (d, 2H), 7.67 (t, 2H), 7.44 (d, 2H), 7.05 (t, 2H), 6.84 (d, 2H), 6.37 (s, 2H), 5.32 (s, 1H), 1.09 (s, 18H), 0.94 (s, 18H). Element Anal. Calcd for C 41 H 51 IrN 2 O 2 (%): C, 61.89; H, 6.42; N, 3.52; found (%): C, 61.76; H, 6.20; N, 3.25. 2.3 LED fabrication and characterization Polymers were dissolved in p -xylene and filtered with a 0.45 μm filter. Patterned indium tin oxide (ITO)-coated glass substrates were cleaned with acetone, detergent, distilled water and isopropanol, subsequently in an ultrasonic bath. After treatment with oxygen plasma, 150 nm of poly-(3,4-ethylenedioxythiophene) (PEDOT) doped with poly(styrenesulfonic acid) (PSS) (Batron-P 4083, Bayer AG) was spin-coated onto the ITO substrate followed by drying in vacuum oven at 80 °C for 8 h. A blend of complex with [PVK + PBD] was spin-cast from a chlorobenzene solution. The film thickness of the active layers was around 75–80 nm, measured with an Alfa Step 500 surface profiler (Tencor). A thin layer of Ba (4–5 nm) and subsequently 200 nm layer of Al were vacuum-evaporated subsequently on top of an EL polymer layer under a vacuum of 1 × 10 −4 Pa. Device performances were measured inside a dry box. Current–voltage ( I – V ) characteristics were recorded with a Keithley 236 source meter. EL spectra were recorded by Oriel Instaspec IV CCD Spectrograph. Luminance was measured by PR 705 photometer (Photo Research). The external quantum efficiencies were determined by a Si photodiode with calibration in an integrating sphere (IS080, Labsphere). 3 Results and discussions 3.1 Synthesis of the complexes The synthetic routes of the bicycloiridium complexes are depicted in Scheme 1 . 2-Arylpyridine ligands were synthesized via palladium catalyzed cross-coupling reaction using the modified method reported previously [17] . The use of zinc rather than lithium leads to favorable results in this coupling reaction between aryl and pyridyl. The reaction was carried out with a yield of over 60%. For the reaction between the chloride-bridged dimmers and the β-diketonate, the yield of bicycloiridium complex depends on the solubility of the reacting substance in the solvent. Compared with the reaction of chloride-bridged dimmers with acetylacetonate, the reaction with 2,2,6,6-tetra-methyl-3,5-heptanedione has a higher yield, and the products are easier to be purified by column chromatography. 3.2 Optical and electrochemical properties The UV–vis absorption of the complexes and the PL spectrum of PVK–PBD in the film [ Fig. 1 (a) ] show a good spectra overlapping. Therefore, the efficient Förster energy transfer from the PVK host to the Ir-complex guests can be expected. The intense absorption peaks below 350 nm are attributed to the spin-allowed singlet state 1 π - π * transition of cyclometalated ligands and the weak absorption peaks around 420 nm can be assigned to the spin-allowed singlet metal-to-ligand charge-transfer ( 1 MLCT) transition [18] .The strong absorption peaks at 465 nm are due to the triplet metal-to-ligand charge-transfer ( 3 MLCT) transition [19] . The spin-forbidden 3 MLCT transition is gained by mixing it with the higher spin-allowed 1 MLCT transition through the strong spin-orbit coupling of iridium. Although the 3 MLCT transition is essentially spin-forbidden, strong spin-orbit coupling on iridium gives a weak absorption of 3 MLCT in such iridium complexes [3,9] . The λ max of 3 MLCT band in (mppy) 2 Ir(tmd) and (bppy) 2 Ir(tmd) are at 465 nm, which are almost the same as (mppy) 2 Ir(acac), and indicates the methyl on the 4-positon of the 2-phenylpyridine, and the alkyl on the acetylacetonate have little influence on the absorption properties of the complexes. The PL spectra of complexes in CH 2 Cl 2 solution are shown in Fig. 1 (b). The maximal emissions of the complexes are about 520 nm, but (mppy) 2 Ir(tmd) and (bppy) 2 Ir(tmd) have a little red shift, which are coincident with those of the absorption spectra. The PL spectra of iridium complexes doped into PVK–PBD (40%) with the same doping concentration (4 wt%) are shown in Fig. 2 a . For (mppy) 2 Ir(acac) and (mppy) 2 Ir(tmd), the host emission is almost entirely quenched, but for (bppy) 2 Ir(tmd), the emission of host is obvious. The PL spectra with different doping concentration of (bppy) 2 Ir(tmd) are shown in Fig. 2 b. With increasing doping concentration, PVK emission decreases gradually, up to 8 wt% the host emission is nearly entirely quenched. To investigate the electronic effects caused by the addition of alkyl groups, cyclic-voltammetry experiments were carried out for the complexes ( Fig. 3 ). Due to the limited range available in CH 2 Cl 2 and the inability of our instrument to measure the reduction potentials, only the oxidation potentials were obtained. The oxidation potentials of (mppy) 2 Ir(tmd) and (bppy) 2 Ir(tmd) show lower oxidative potentials than that of (mppy) 2 Ir(acac), which can be ascribed to the electron-donating ability of the alkyl in the ligands. Meanwhile the similar CV characteristics of both substituted complexes indicate that the effect of methyl and ter -butyl is parallel on the oxidative potentials of the bicycloiridium complexes. 3.3 Device performances A double-layer device was fabricated in the configuration: ITO/PEDOT/PVK/complex + PVK–PBD (40%)/Ba/Al. PBD as an electron transport [6,8] and PVK as host are the chosen materials in electrophosphorescent devices. The EL spectra of the complexes with the same doping concentration in PVK–PBD are shown in Fig. 4 a . Like the PL spectra, EL peaks of (mppy) 2 Ir(tmd) and (bppy) 2 Ir(tmd) doped in PVK are slight red shifted compared with (mppy) 2 Ir(acac). Fig. 4 b shows the EL spectra of (bppy) 2 Ir(tmd) doped into PVK–PBD with different concentration. It can be seen that the EL peaks are fixed with the different doping concentration. There is an effective energy transfer of the excitons from PVK to Ir-complex even though the doping concentration is as low as 1 wt%. The substantial difference of energy transfer efficiencies between the PL and EL for the doping system implies that different mechanisms are involved [20] . Under photoexcitation, the singlet excited states are created on the main chain and subsequently transfer to the metal–organic complex by Förster energy transfer. In contrast, the electrons and holes are trapped on the Ir-complex after the injection of the electrons from the cathode and the holes from the opposite anode in the device [20,21] . Preliminary device performances (although not optimized) are encouraging ( Table 1 ). All of the devices show high efficiency and luminance. Fig. 5 a shows the external quantum efficiency versus the current density of complexes with the same doping concentration (4 wt%) in PVK–PBD. The device performances of (bppy) 2 Ir(tmd) and (mppy) 2 Ir(tmd) are better than those of (mppy) 2 Ir(acac), and (bppy) 2 Ir(tmd) is the best. So it follows that the alkyl substitutions of bicycloiridium complex either on β-diketonate or phenylpyridine ligand are both effective in improving the doping device performances. Fig. 5 b shows the external quantum efficiency versus the current density of (bppy) 2 Ir(tmd) with different concentration. The device performances show a moderate dependence on the doping concentration. The best device performance is observed for the (bppy) 2 Ir(tmd)-doped PVK–PBD device with the concentration of 1 wt%. A maximal external quantum efficiency of QE ext = 14.2% ph/el and a luminous efficiency of (LE) = 33 cd/A with a luminance of 2099 mA/cm 2 are achieved at a current density of 6.4 mA/cm 2 , among the highest reported values for polymer phosphorescent emitters. The device efficiencies obtained in our study increase with the increase in current density initially, and then show a gentle decay with further increase in current density up to 100 mA/cm 2 , which indicates that the branching substitution in the ligands of the complexes may have an advantage in the depression of concentration quenching and T – T annihilation, thus arising the quenching mechanism for the blend system at a high current density. 4 Conclusion In summary, the alkyl-substituted bicycloiridium complexes on the acetylacetonate ligand were synthesized and the high efficient green electrophosphorescent PLED based on the complexes doped in PVK–PBD were achieved. It is shown that the alkyl substitution on bidentate ancillary ligand also has a great effect on optimizing the LED performance for the bicycloiridium complexes. Acknowledgments The authors are grateful to the Ministry of Science and Technology of China (No. 2002CB613403), the National Natural Science Foundation of China (No. 50173008) and the Natural Science Foundation of Guang-dong Province (No. 11545) for their financial support to our work. References [1] Y.G. Ma H.Y. Zhang J.C. Shen C.M. Chen Synth. Met. 94 1998 245 [2] M.A. Baldo D.F. O’Brien Y. You A. Shoustikov S. Sibley M.E. Thompson S.R. Forrest Nature 395 1998 151 [3] S. Lamansky P. Djurovich D. Murphy F. Abdel-Razaq H.E. Lee C. Adachi P.E. Burrows S.R. Forrest M.E. Thompson J. Am. Chem. Soc. 123 2001 4304 [4] C. Adachi M.A. Baldo S.R. Forrest M.E. Thompson Appl. Phys. Lett. 77 2000 904 [5] Y. Wang N. Herron V.V. Grushin D. Lecloux V. Petrov Appl. Phys. Lett. 79 2001 449 [6] C. Adachi M.A. Baldo S.R. Forrest S. Lamansky M.E. Thompson R.C. Kwong Appl. Phys. Lett. 78 2001 1622 [7] C. Adachi M.A. Baldo M.E. Thompson S.R. Forrest J. Appl. Phys. 90 2001 5048 [8] C.Y. Jiang W. Yang J.B. Peng S. Xiao Y. Cao Adv. Mater. 16 2004 537 [9] T. Tsuzuki N. Shirasawa T. Suzuki S. Tokito Adv. Mater. 15 2003 1455 [10] G.T. Lei L.D. Wang L. Duan J.H. Wang Y. Qiu Synth. Met. 144 2004 249 [11] W.G. Zhu Y.Q. Mo L.J. Su W. Yang Y. Cao Appl. Phys. Lett. 80 12 2002 2045 [12] S. Lamansky P.I. Djurovich D. Murphy F. Abdel-Razzaq H.-E. Lee C. Adachi P.E. Burrows S.R. Forrest M.E. Thompson J. Am. Chem. Soc. 123 2001 4304 [13] V.V. Grushin N. Herron D.D. LeCloux W.J. Marshall V.A. Petrov Y. Wang Chem. Commun. 2001 1494 [14] P. Djurovich D. Murphy F. Abdel-Razzaq R. Kwong I. Tsyba M. Bortz B. Mui R. Bau M.E. Thompson Inorg. Chem. 40 2001 1704 [15] S. Jung Y. Kang H.S. Kim Y.H. Kim C.L. Lee J.J. Kim S.K. Lee S.K. Kwon Eur. J. Inorg. Chem. 2004 3415 3423 [16] C.L. Lee K.B. Lee J.J. Kim Appl. Phys. Lett. 77 15 2000 2280 2290 [17] W.G. Zhu C.Z. Liu L.J. Su W. Yang Y. Ming Y. Cao J. Mater. Chem. 13 2003 50 55 [18] Y.J. Su H.L. Huang C.L. Li C.H. Chien Y.T. Tao P.T. Chou S. Datta R.S. Liu Adv. Mater. 15 2003 884 [19] M.G. Colombo A. Hauser H.U. Gudel Inorg. Chem. 32 1993 3088 [20] M.D. McGehee T. Bergstedt C. Zhang A.P. Saab M.B. O’Regan G.C. Bazan V.I. Srdanov A.J. Heeger Adv. Mater. 11 1999 1349 [21] X. Gong M.R. Robinson J.C. Ostrowski D. Moses G.C. Bazan A.J. Heeger Adv. Mater. 14 8 2002 581",
        "keywords": [
            "alkyl substitution",
            "bicycloiridium complex",
            "doping",
            "pled",
            "pvk",
            "light emitting diode",
            "external quantum efficiency",
            "current density"
        ],
        "authors": [
            {
                "name": "Hongyu Zhen",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Laboratory of Specially Functional Materials and Advanced Manufacturing Technology, South China University of Technology, Guangzhou 510640, China"
            },
            {
                "name": "Changyun Jiang",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Laboratory of Specially Functional Materials and Advanced Manufacturing Technology, South China University of Technology, Guangzhou 510640, China"
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Xingrong Zeng",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Laboratory of Specially Functional Materials and Advanced Manufacturing Technology, South China University of Technology, Guangzhou 510640, China"
            },
            {
                "name": "Chi Zhang",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Laboratory of Specially Functional Materials and Advanced Manufacturing Technology, South China University of Technology, Guangzhou 510640, China"
            },
            {
                "name": "Yong Cao",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Laboratory of Specially Functional Materials and Advanced Manufacturing Technology, South China University of Technology, Guangzhou 510640, China"
            }
        ],
        "venue": "Synthetic Metals",
        "year": 2005
    },
    "bXIjHctM": {
        "id": "bXIjHctM",
        "title": "Novel saturated red-emitting poly(p-phenylenevinylene) copolymers with narrow-band-gap units of 2,1,3-benzothiadiazole synthesized by a palladium-catalyzed Stille coupling reaction",
        "abstract": "",
        "keywords": [
            "2",
            "1",
            "3-benzothiadiazole",
            "conjugated polymer",
            "electroluminescence",
            "narrow band gap",
            "optical properties",
            "poly(p-phenylenevinylene) (ppv)",
            "polymer light-emitting diodes (pleds)",
            "saturated red emitters",
            "stille coupling reaction",
            "band gap"
        ],
        "authors": [
            {
                "name": "Xianzhen Li",
                "org": ""
            },
            {
                "name": "Yong Zhang",
                "org": ""
            },
            {
                "name": "Renqiang Yang",
                "org": ""
            },
            {
                "name": "Jian Huang",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Yong Cao",
                "org": ""
            }
        ],
        "venue": "Journal of Polymer Science Part A-polymer Chemistry",
        "year": 2005
    },
    "J32RhNh0": {
        "id": "J32RhNh0",
        "title": "Synthesis and properties of electrophosphorescent chelating polymers with iridium complexes in the conjugated backbone.",
        "abstract": "The synthesis of electrophosphorescent chelating polymers by Suzuki polycondensation of A-A- and B-B-type monomers is described, in which the fluorene-alt-carbazole (PFCz) segment is used as polymer backbone. By using alkyl-substituted ligands of iridium complex monomers, chelating copolymers with higher contents of iridium complex can be synthesized. Chemical and photophysical characterization confirm that the Ir complex is incorporated into the polymer backbone as one of the monomer repeat units by means of two 5-bromotolylpyridine ligands. Chelating polymers with Ir complexes in the conjugated polymer backbone show highly efficient energy transfer of excitons from the PFCz host segment to the Ir complex by an intramolecular trapping mechanism. The external quantum and luminous efficiencies of a device made with PFCzMppyIrhm4 copolymer reach 4.1 % ph/el (photons/electron) and 5.4 cd A(-1), respectively, at a current density of 32.2 mA cm(-2), an emission peak of 577 nm, and a luminance of 1730 cd cm(-2). Most important, the devices made from the chelating copolymers show no notable efficiency decay with increasing current density due to reduced concentration quenching and triplet-triplet (T-T) annihilation. This indicates that incorporation of the phosphorescent complex into the rigid conjugated polymer main chain is a new way to simultaneously realize high efficiency, long-term stability, and simple processing of phosphorescent polymer light-emitting diodes.",
        "keywords": [
            "polymers",
            "polymerization",
            "luminescence",
            "chelates",
            "iridium"
        ],
        "authors": [
            {
                "name": "Hongyu Zhen",
                "org": ""
            },
            {
                "name": "Changyun Jiang",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Jiaxing Jiang",
                "org": ""
            },
            {
                "name": "Fei Huang",
                "org": ""
            },
            {
                "name": "Yong Cao",
                "org": ""
            }
        ],
        "venue": "Chemistry (Weinheim an der Bergstrasse, Germany)",
        "year": 2005
    },
    "mN27sZuq": {
        "id": "mN27sZuq",
        "title": "Light-emitting copolymers based on fluorene and selenophene?Comparative studies with its sulfur analogue: Poly(fluorene-co-thiophene)",
        "abstract": "",
        "keywords": [
            "conjugated polymers",
            "fluorescence",
            "light-emitting diodes",
            "poly(fluorene- cothiophene)",
            "poly(fluorene-co-selenophene)",
            "light emitting diodes",
            "comparative study"
        ],
        "authors": [
            {
                "name": "Renqiang Yang",
                "org": ""
            },
            {
                "name": "Renyu Tian",
                "org": ""
            },
            {
                "name": "Qiong Hou",
                "org": ""
            },
            {
                "name": "Yong Zhang",
                "org": ""
            },
            {
                "name": "Yongfang Li",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Chi Zhang",
                "org": ""
            },
            {
                "name": "Yong Cao",
                "org": ""
            }
        ],
        "venue": "Journal of Polymer Science Part A-polymer Chemistry",
        "year": 2005
    },
    "N3VGvdi3": {
        "id": "N3VGvdi3",
        "title": "High-efficiency electroluminescent polymers with stable high work function metal Al and Au as cathode",
        "abstract": "Soluble conjugated copolymers (PFN-TPA) derived from 2,1,3-benzothiadiazole (BTDZ), triphenylamine (TPA) and 9,9-bis(3′-( N , N -dimethylamino)propyl)fluorene (DMAPF) were synthesized by palladium(0)-catalyzed Suzuki coupling reactions. Optoelectronic properties of the copolymers were characterized by UV–vis absorption, cyclic voltammetry, photoluminescence and electroluminescence. All these copolymers show excellent EL performances in the devices with Ba/Al, Al and even Au as cathode and are promising candidate for fabrication and patterning of air-stable flat panel displays.",
        "keywords": [
            "polyfluorene",
            "light emitting diode",
            "cationic polyelectrolyte",
            "electroluminescence",
            "work function"
        ],
        "authors": [
            {
                "name": "Fei Huang",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Laboratory of Special Functional Materials and Advanced Manufacturing Technology, South China University of Technology, Guangzhou 510640, China"
            },
            {
                "name": "Lintao Hou",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Laboratory of Special Functional Materials and Advanced Manufacturing Technology, South China University of Technology, Guangzhou 510640, China"
            },
            {
                "name": "Wei Shi",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Laboratory of Special Functional Materials and Advanced Manufacturing Technology, South China University of Technology, Guangzhou 510640, China"
            },
            {
                "name": "Wei Cao",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Laboratory of Special Functional Materials and Advanced Manufacturing Technology, South China University of Technology, Guangzhou 510640, China"
            },
            {
                "name": "Qiong Hou",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Laboratory of Special Functional Materials and Advanced Manufacturing Technology, South China University of Technology, Guangzhou 510640, China"
            },
            {
                "name": "Wei Yang",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Laboratory of Special Functional Materials and Advanced Manufacturing Technology, South China University of Technology, Guangzhou 510640, China"
            },
            {
                "name": "Yong Cao",
                "org": ""
            }
        ],
        "venue": "European Polymer Journal",
        "year": 2006
    },
    "SYvBCqSH": {
        "id": "SYvBCqSH",
        "title": "Electrophosphorescent Chelating Copolymers Based on Linkage Isomers of Naphthylpyridine−Iridium Complexes with Fluorene",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Hongyu Zhen",
                "org": ""
            },
            {
                "name": "Chan Luo",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Wuyuan Song",
                "org": ""
            },
            {
                "name": "Bin Du",
                "org": ""
            },
            {
                "name": "Jiaxing Jiang",
                "org": ""
            },
            {
                "name": "Changyun Jiang",
                "org": ""
            },
            {
                "name": "Yong Zhang",
                "org": ""
            },
            {
                "name": "Yong Cao",
                "org": ""
            }
        ],
        "venue": "Macromolecules",
        "year": 2006
    },
    "x9pUnPgG": {
        "id": "x9pUnPgG",
        "title": "Synthesis and properties of novel deep red-emitting copolymers based on a poly(p-phenylenevinylene) derivative",
        "abstract": "",
        "keywords": [
            "electroluminescence",
            "narrow band-gap",
            "poly(p-phenylenevinylene) (ppv)",
            "polymer light-emitting diodes (pleds)",
            "stille coupling reaction"
        ],
        "authors": [
            {
                "name": "Xianzhen Li",
                "org": ""
            },
            {
                "name": "Wenjin Zeng",
                "org": ""
            },
            {
                "name": "Yangjun Xia",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Yong Cao",
                "org": ""
            }
        ],
        "venue": "Journal of Applied Polymer Science",
        "year": 2006
    },
    "IyKGSuxd": {
        "id": "IyKGSuxd",
        "title": "White-Light Emission from a Single Polymer with Singlet and Triplet Chromophores on the Backbone",
        "abstract": "",
        "keywords": [
            "light-emitting diodes (leds)",
            "luminescence",
            "polyfluorene",
            "singlet and triplet chromophores",
            "white-light emission",
            "organic light emitting diodes",
            "suzuki coupling",
            "quantum yield",
            "photoluminescence",
            "electroluminescence"
        ],
        "authors": [
            {
                "name": "Hongyu Zhen",
                "org": ""
            },
            {
                "name": "Wei Xu",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Qiliang Chen",
                "org": ""
            },
            {
                "name": "Yunhua Xu",
                "org": ""
            },
            {
                "name": "Jiaxing Jiang",
                "org": ""
            },
            {
                "name": "Junbiao Peng",
                "org": ""
            },
            {
                "name": "Yong Cao",
                "org": ""
            }
        ],
        "venue": "Macromolecular Rapid Communications",
        "year": 2006
    },
    "4KqDQRZC": {
        "id": "4KqDQRZC",
        "title": "Electrophosphorescent chelating copolymers based on linkage isomers of naphthylpyridine-iridium complexes with fluorene",
        "abstract": "A series of phosphorescent chelating copolymers based on the linkage isomers of 2-(1-naphthalene)-pyridine- and 2-(2-naphthalene)pyridine- bicycloiridium complexes were synthesized by Suzuki polycondensation of A-A- and B-B-type monomers. These linkage isomers-based copolymers show distinct differences in their photophysical and electroluminescence properties. The phosphorescent emission band of the copolymer PF1-Npylrm is in the region of 630 nm, whereas copolymers PF2-Npylrm show an emission with the peak maximum at 590 nm, which are both red-shifted around 20 nm compared with the emissions of the pristine complexes. The highly efficient saturated red-phosphorescent PLEDs were achieved on the basis of copolymers PF1-Npylrm. The best device performances are observed from copolymer PF1-Npylrml with an external quantum efficiency (ηexl) of 6.5% photon/electron (ph/el) at the current density of 38 mA/cm2, with the emission peak at 630 nm (x = 0.65, y = 0.31) and the luminance of 926 cd/m2. The efficiency remains as high as ηext = 5.3% ph/el at a high current density of 100 mA/cm 2. No remarkable efficiency decay with the increase in current density shows that the chelating copolymers are promising candidate materials for phosphorescent polymer light-emitting diodes (PHPLEDs). © 2006 American Chemical Society.",
        "keywords": [],
        "authors": [
            {
                "name": "Hongyu Znen",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Chan Luo",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Wei Yang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "WuYuan Song",
                "org": "Guangdong Entry-Exit Inspection and Quarantine Bureau(Guangzhou Entry-Exit Inspection and Quarantine Bureau,Guangdong Entry-Exit Inspection and Quarantine Bureau),Guangzhou,China"
            },
            {
                "name": "Bin Du",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Jiaxing Jiang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Changyun Jiang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Yong Zhang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Yong Cao",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            }
        ],
        "venue": "Macromolecules",
        "year": 2006
    },
    "xMv4T5cS": {
        "id": "xMv4T5cS",
        "title": "Poly(3,6-silafluorene-co-2,7-fluorene)-based high-efficiency and color-pure blue light-emitting polymers with extremely narrow band-width and high spectral stability",
        "abstract": "A new series of copolymers (PSiFF) based on 3,6-silafluorene and 2,7-fluorene were synthesized via the Suzuki polycondensation. The influences of the 3,6-silafluorene content in the copolymers on the thermal, photophysical, electroluminescence and electrochemical properties were investigated. The incorporation of 3,6-silafluorene into the polyfluorene main chain not only suppressed the long-wavelength emission but significantly improved the efficiency and color purity of the copolymer-based devices. Both fluorene and 3,6-silafluorene took part in p-conjugation of the main chain and the electroluminescence spectra were remarkably blue-shifted with increasing wide bandgap 3,6-silafluorene content. The device based on PSiFF90 with the configuration of ITO/PEDOT : PSS/PVK/polymer/Ba/Al showed a quantum efficiency of 3.34% and a luminous efficiency of 2.02 cd A 21 at a brightness of 326 cd m 22 with CIE 1931 chromaticity coordinates of (0.16, 0.07), which almost match the NTSC standard blue pixel coordinates of (0.14, 0.08). Moreover, the incorporation of 3,6-silafluorene into the polyfluorene main chain significantly improved the spectral stability at annealing. The results indicate poly(3,6-silafluorene-co-2,7-fluorene) could be a promising candidate for blue-emitting polymers of high efficiency and good color purity.",
        "keywords": [
            "quantum efficiency",
            "electroluminescence"
        ],
        "authors": [
            {
                "name": "Ergang Wang",
                "org": ""
            },
            {
                "name": "Chun Li",
                "org": ""
            },
            {
                "name": "Yueqi Mo",
                "org": ""
            },
            {
                "name": "Yong Zhang",
                "org": ""
            },
            {
                "name": "Gang Ma",
                "org": ""
            },
            {
                "name": "Wei Shi",
                "org": ""
            },
            {
                "name": "Junbiao Peng",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Yong Cao",
                "org": ""
            }
        ],
        "venue": "Journal of Materials Chemistry",
        "year": 2006
    },
    "djM3rZSh": {
        "id": "djM3rZSh",
        "title": "Synthesis of novel triphenylamine-based conjugated polyelectrolytes and their application as hole-transport layers in polymeric light-emitting diodes",
        "abstract": "",
        "keywords": [
            "transport layer",
            "light emitting diode"
        ],
        "authors": [
            {
                "name": "Wei Shi",
                "org": ""
            },
            {
                "name": "Suqin Fan",
                "org": ""
            },
            {
                "name": "Fei Huang",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Ransheng Liu",
                "org": ""
            },
            {
                "name": "Yong Cao",
                "org": ""
            }
        ],
        "venue": "Journal of Materials Chemistry",
        "year": 2006
    },
    "Wt88iXMy": {
        "id": "Wt88iXMy",
        "title": "Recent Advances in Organometallic Polymers as Highly Efficient Electrophosphorescent Emitters",
        "abstract": "Recent progress and development of organometallic electrophosphorescent polymers, which attracted increasing interest of researchers\n in the field of phosphorescent light-emitting devices, has been reviewed. The synthesis, structural characterization, photoluminescence,\n electroluminescence and possible application of electrophosphorescent polymers are surveyed and discussed.\n ",
        "keywords": [
            "Organometallic polymers",
            "electrophosphorescence",
            "transition metal",
            "energy transfer"
        ],
        "authors": [
            {
                "name": "Jiaxing Jiang",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology Key Laboratory of Specially Functional Materials Guangzhou 510640 P. R. China Guangzhou 510640 P. R. China"
            },
            {
                "name": "Wei Yang",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology Key Laboratory of Specially Functional Materials Guangzhou 510640 P. R. China Guangzhou 510640 P. R. China"
            },
            {
                "name": "Yong Cao",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology Key Laboratory of Specially Functional Materials Guangzhou 510640 P. R. China Guangzhou 510640 P. R. China"
            }
        ],
        "venue": "Journal of Inorganic and Organometallic Polymers and Materials",
        "year": 2007
    },
    "OVcvoiwE": {
        "id": "OVcvoiwE",
        "title": "Near-infrared response photovoltaic device based on novel narrow band gap small molecule and PCBM fabricated by solution processing",
        "abstract": "In this paper, we report on synthesis of a novel diphenylaminofluorenyl-capped thiadiazoloquinoxaline (6,7-dimethyl-4,9-di{5-[9,9-bis(octyl)-7-diphenylaminofluorene-2-yl]-4-hexylthien-2-yl}[1,2,5]-thiadiazolo[3,4-g]quinoxaline (DPAFL-TDOX-DPAFL which is further abbreviated to TDOX), Scheme 1) and its use as donor material for the realization of efficient bulk-heterojunction organic solar cell by spin coating from blend with PCBM as acceptor. TDOX showed very good solution processibility and film uniformity up to weight ratio TDOX:PCBM=1:4. Spectral response was extended to near-infrared region (at around 1000 nm) with energy conversion efficiency (ECE) 0.75% and short-curcuit current density 1.95 mA/cm 2. © 2007 Elsevier B.V. All rights reserved.",
        "keywords": [
            "heterojunction",
            "narrow band gap",
            "near-infrared response",
            "solar cells",
            "solution processing",
            "energy conversion",
            "band gap",
            "current density",
            "near infrared",
            "organic solar cell"
        ],
        "authors": [
            {
                "name": "Mingliang Sun",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology, Key Lab of Specially Functional Materials, Ministry of Education, Wushan Road, Guangzhou 510640, People's Republic of China"
            },
            {
                "name": "Li Wang",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology, Key Lab of Specially Functional Materials, Ministry of Education, Wushan Road, Guangzhou 510640, People's Republic of China"
            },
            {
                "name": "Xuhui Zhu",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology, Key Lab of Specially Functional Materials, Ministry of Education, Wushan Road, Guangzhou 510640, People's Republic of China"
            },
            {
                "name": "Bin Du",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology, Key Lab of Specially Functional Materials, Ministry of Education, Wushan Road, Guangzhou 510640, People's Republic of China"
            },
            {
                "name": "Ransheng Liu",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology, Key Lab of Specially Functional Materials, Ministry of Education, Wushan Road, Guangzhou 510640, People's Republic of China"
            },
            {
                "name": "Wei Yang",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology, Key Lab of Specially Functional Materials, Ministry of Education, Wushan Road, Guangzhou 510640, People's Republic of China"
            },
            {
                "name": "Yong Cao",
                "org": ""
            }
        ],
        "venue": "Solar Energy Materials and Solar Cells",
        "year": 2007
    },
    "tmL1Mb0F": {
        "id": "tmL1Mb0F",
        "title": "Fluorene-based copolymers for color-stable blue light-emitting diodes",
        "abstract": "A series of random conjugated copolymers (PFO-HBT) derived from 9,9-dioctylfluorene (DOF) and 2-hexylbenzotriazole (HBT) is prepared by the palladium-catalyzed Suzuki coupling reaction with the feed HBT molar ratio around 1%, 5% and 15%. By copolymerizing 2-hexylbenzotriazole into the backbone of polyfluorene, an efficient colorfast blue light-emitting polymer system is developed. The device with the structure of ITO (indium tin oxide)/PEDOT/PVK/PFO-HBT1/Ba/Al exhibits the highest external quantum efficiency 1.62% with luminance efficiency of 2.69 cd/A, power efficiency of 1.25 lm/W and the CIE coordinates of (0.15, 0.17). The EL spectra are stable at the increased current density and continuous operation without significant change of CIE. Keywords Blue emitter Polymer light emitting device Polyfluorene 2-hexylbenzotriazole (HBT) Electroluminescence",
        "keywords": [
            "2-hexylbenzotriazole (hbt)",
            "blue emitter",
            "electroluminescence",
            "polyfluorene",
            "polymer light emitting device",
            "power efficiency",
            "indium tin oxide",
            "external quantum efficiency",
            "current density"
        ],
        "authors": [
            {
                "name": "Mingliang Sun",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Laboratory of Special Functional Materials, South China University of Technology, Guangzhou 510640, People’s Republic of China"
            },
            {
                "name": "Qiaoli Niu",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Laboratory of Special Functional Materials, South China University of Technology, Guangzhou 510640, People’s Republic of China"
            },
            {
                "name": "Renqiang Yang",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Laboratory of Special Functional Materials, South China University of Technology, Guangzhou 510640, People’s Republic of China"
            },
            {
                "name": "Bin Du",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Laboratory of Special Functional Materials, South China University of Technology, Guangzhou 510640, People’s Republic of China"
            },
            {
                "name": "Ransheng Liu",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Laboratory of Special Functional Materials, South China University of Technology, Guangzhou 510640, People’s Republic of China"
            },
            {
                "name": "Wei Yang",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Laboratory of Special Functional Materials, South China University of Technology, Guangzhou 510640, People’s Republic of China"
            },
            {
                "name": "Junbiao Peng",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Laboratory of Special Functional Materials, South China University of Technology, Guangzhou 510640, People’s Republic of China"
            },
            {
                "name": "Yong Cao",
                "org": ""
            }
        ],
        "venue": "European Polymer Journal",
        "year": 2007
    },
    "h4V8aLSg": {
        "id": "h4V8aLSg",
        "title": "Application of an analytical phase transformation model",
        "abstract": "An analytical phase transformation model has been used to study the kinetics of crystallization of amorphous alloys sub- jected to either isothermal or isochronal anneals. The model has been applied to Mg82.3Cu17.7 and Pd40Cu30P20Ni10, employing iso- thermal and isochronal differential scanning calorimetry. Applying different combinations of nucleation and growth mechanisms to the same experiments, the nucleation and growth modes dominating the crystallization and the values for the corresponding kinetic parameters, including the constant activation energies for nucleation and growth, have been determined. Further, the influence of isothermal pre-annealing on subsequent isochronal crystallization kinetics, involving a gradual change of nucleation mode up to site saturation with increase of pre-annealing, can be analyzed.",
        "keywords": [
            "heat treatment",
            "phase transformation",
            "crystal growth",
            "metallic glass",
            "calorimetry"
        ],
        "authors": [
            {
                "name": "Feng Liu",
                "org": ""
            },
            {
                "name": "Changlin Yang",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Gencang Yang",
                "org": ""
            },
            {
                "name": "Yaohe Zhou",
                "org": ""
            }
        ],
        "venue": "Journal of University of Science and Technology Beijing",
        "year": 2007
    },
    "jpMkS2Ct": {
        "id": "jpMkS2Ct",
        "title": "Synthesis and optoelectronic characterization of conjugated phosphorescent polyelectrolytes with a neutral Ir complex incorporated into the polymer backbone and their neutral precursors",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Yong Zhang",
                "org": ""
            },
            {
                "name": "Yunhua Xu",
                "org": ""
            },
            {
                "name": "Qiaoli Niu",
                "org": ""
            },
            {
                "name": "Junbiao Peng",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Xuhui Zhu",
                "org": ""
            },
            {
                "name": "Yong Cao",
                "org": ""
            }
        ],
        "venue": "Journal of Materials Chemistry",
        "year": 2007
    },
    "0TFA7Pvd": {
        "id": "0TFA7Pvd",
        "title": "Polyfluorene Polyelectrolytes and Their Precursors Processable from Environment-Friendly Solvents (Alcohol or Water) for PLED Applications",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Fei Huang",
                "org": ""
            },
            {
                "name": "Hongbin Wu",
                "org": ""
            },
            {
                "name": "Junbiao Peng",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Yong Cao",
                "org": ""
            }
        ],
        "venue": "Current Organic Chemistry",
        "year": 2007
    },
    "vFUb0edK": {
        "id": "vFUb0edK",
        "title": "Efficient white-light-emitting diodes based on polyfluorene doped with fluorescent chromophores",
        "abstract": "Orange-red emitting small molecule chromorephores, 4,7-di-2-thienyl-2,1,3- benzothiadiazole, 4,7-(2′-diselenophenyl)-2,1,3- benzothiadiazole, and 4,7-bis(N-methylpyrrol-2-yl)-2,1,3-benzo-thiadiazole were synthesized and used for fabrication of fluorescent white-emitting device with polyfluorene (PFO) as host by solution processing. By careful controlling of dopant concentration, balanced narrow band-gap (NGB) electroluminescence (EL) emission can be obtained by solution processing due to the incomplete energy transfer from PFO to narrow band gap molecules. EL spectra of the obtained devices were very stable at a wide range of operating voltage. The best white-emitting device reached luminous efficiency of 7.54 cdA with the CIE coordinates (0.33, 0.34) at luminance over 1000 cd m2. © 2007 American Institute of Physics.",
        "keywords": [
            "energy transfer",
            "electroluminescence",
            "band gap"
        ],
        "authors": [
            {
                "name": "Suqin Fan",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Mingliang Sun",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Jian Wang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Wei Yang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Yong Cao",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            }
        ],
        "venue": "Applied Physics Letters",
        "year": 2007
    },
    "oBfWxA5B": {
        "id": "oBfWxA5B",
        "title": "Extremely Color-Stable Blue Light-Emitting Polymers Based on Alternating 2,7-Fluorene-co-3,9-carbazole Copolymer",
        "abstract": "",
        "keywords": [
            "blue light-emitting",
            "carbazole",
            "polyfluorene",
            "thermal annealing"
        ],
        "authors": [
            {
                "name": "Ransheng Liu",
                "org": ""
            },
            {
                "name": "Yan Xiong",
                "org": ""
            },
            {
                "name": "Wenjin Zeng",
                "org": ""
            },
            {
                "name": "Zhonglian Wu",
                "org": ""
            },
            {
                "name": "Bin Du",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Mingliang Sun",
                "org": ""
            },
            {
                "name": "Yong Cao",
                "org": ""
            }
        ],
        "venue": "Macromolecular Chemistry and Physics",
        "year": 2007
    },
    "68qGXnJg": {
        "id": "68qGXnJg",
        "title": "High-efficiency electrophosphorescent copolymers containing charged iridium complexes in the side chains.",
        "abstract": "A convenient approach to novel charged Ir polymers for optoelectronic devices to achieve red emission was developed. 2-(Pyridin-2-yl)benzimidazole units grafted into the side chains of macroligands (PFCz and PFP) served as ligands for the formation of charged Ir complex pendants with 1-phenylisoquinoline (1-piq). The charged Ir polymers (PFPIrPiq and PFCzIrPiq) showed exclusive Ir(1-piq)(2){N-[2-(pyridin-2-yl)benzimidazole]hexyl}(+)BF(4)(-) (IrPiq) emission, with the peak at 595 nm. The best device performances were obtained from PFCzIrPiq4 with the device configuration of ITO/PEDOT:PSS/PFCzIrPiq4+PBD (30 wt %)/TPBI/Ba/Al (PBD: 5-(4-tert-butylphenyl)-2-(biphenyl-4-yl)-1,3,4-oxadiazole; TPBI: 1,3,5-tris-(2-N-phenylbenzimidazolyl)benzene). A maximum external quantum efficiency (EQE) of 7.3 % and a luminous efficiency (LE) of 6.9 cd A(-1) with a luminance of 138 cd m(-2) were achieved at a current density of 1.9 mA cm(-2). The efficiencies remained as high as EQE=3.4 % and LE=3.3 cd A(-1) with a luminance of 3770 cd m(-2) at a current density of 115 mA cm(-2). The single-layer devices based on charged Ir polymers also showed high efficiency with the high work-function metal Ag as cathode. The maximum external quantum efficiencies of the devices were 0.64 % and 0.66 % for PFPIrPiq2 and PFPIrPiq10, respectively. A possible mechanism of an electrochemical cell associated with its electrochemical redox pathway for single-layer devices has been proposed. The results showed that the charged Ir polymers are promising candidate materials for polymer optoelectronic devices.",
        "keywords": [
            "host-guest systems",
            "polymers",
            "luminescence",
            "n ligands",
            "iridium"
        ],
        "authors": [
            {
                "name": "Bin Du",
                "org": ""
            },
            {
                "name": "Lei Wang",
                "org": ""
            },
            {
                "name": "HongBin Wu",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Yong Zhang",
                "org": ""
            },
            {
                "name": "RanSheng Liu",
                "org": ""
            },
            {
                "name": "MingLiang Sun",
                "org": ""
            },
            {
                "name": "Junbiao Peng",
                "org": ""
            },
            {
                "name": "Yong Cao",
                "org": ""
            }
        ],
        "venue": "Chemistry (Weinheim an der Bergstrasse, Germany)",
        "year": 2007
    },
    "aT9YVXWm": {
        "id": "aT9YVXWm",
        "title": "Bright red light-emitting devices based on a novel europium complex doped into polyvinylcarbazole",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Yong Zhang",
                "org": ""
            },
            {
                "name": "Chun Li",
                "org": ""
            },
            {
                "name": "Huahong Shi",
                "org": ""
            },
            {
                "name": "Bin Du",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Yong Cao",
                "org": ""
            }
        ],
        "venue": "New Journal of Chemistry",
        "year": 2007
    },
    "1Wn6maNW": {
        "id": "1Wn6maNW",
        "title": "Novel chemosensory materials based on polyfluorenes with 2-(2′-pyridyl)-benzimidazole and 5-methyl-3-(pyridin-2-yl)-1,2,4-triazole groups in the side chain",
        "abstract": "Polyfluorenes with 2-(2′-pyridyl)-benzimidazole (P1, P2 and P4) and 5-methyl-3-(pyridin-2-yl)-1,2,4-triazole (P3) groups in the side chain were synthesized by Suzuki polycondensation. The responsive properties of polymers on metal ions and H + were investigated by absorption and emission spectra. The fluorescences of polymers (P1–P4) were completely quenched upon the transition metal ions such as Co 2+ , Ni 2+ , Fe 3+ and Ag + due to the enhanced electronic communication properties of conjugated polymers. The obvious differences to Ni 2+ ion responsive sensitivity were observed between P1 and P4 polymers. The fluorescences of P1 and P4 were quenched to 50 ( I 0 / I ) and to 22 ( I 0 / I ) upon the addition of a Ni 2+ solution of 3.2 × 10 −6 M, as well as 5.0 × 10 −6 M, respectively, owing to the different conjugated backbone. The fluorescences of P2 and P3 were completely and hardly quenched upon the addition of a Al 3+ solution of 1.0 × 10 −4 M, respectively, owing to the different receptors in the side chain. P2 showed good selectivity to Ni 2+ ion in the range of quencher concentration as low as 5 ppm, owing to the different chelating abilities of receptor with ions. Cu 2+ and Mn 2+ ions hardly quenched the fluorescences of polymers (P1–P4), which were different from the oligopyridyl-functionalized conjugated polymers. The results further opened the opportunities to develop the tailored sensory materials through the appropriate alteration of receptors in the side chain and the conjugated backbone. Keywords Polyfluorene Fluorescent chemosensor Responsive property 1 Introduction Conjugated polymers have attracted great attention due to their potential applications as light-emitting diodes [1] , photovoltaic devices [2] , field-effect transistors [3] , and biological and chemical sensors [4] . Conjugated polymers with special receptors can be used in detecting a wide range of analytes from explosives to biomolecules. Sensitive detection methods employed for sensing metal ions involve the design of “turn-on” fluorescent chemosensors on the basis of the photoinduced electron transfer (PET) mechanism in conjugated polymers. Fan et al. reported that conjugated polymers with N , N , N -trimethylethylenediamino groups as receptors, on a poly[ p -(phenyleneethylene)- alt -(thienyleneethynylene)] (PPETE) fluorescent conjugated polymer backbone, showed fluorescence enhancement upon binding Hg 2+ , protons and other divalent cations [5] . The vast majority of the detection methods involve a “turn-off” effect in the presence of analytes. The conjugated “molecular wire” polymer greatly amplified the fluorescence quenching due to facile energy migration along the polymer backbone upon the excitations and the concept was first established by Zhou and Swager [6] . Aza crown and crown ethers were investigated only for alkali metal ions with the selectivity depending on the size matching between metal ions and the inner diameter of receptor [7] . For other metal ions, ligands such as quinoline, pyridine, 2,2′-bipyridine, terpyridine and 1,10-phenanthroline groups have been successfully introduced into the backbone of conjugated polymers and these polymers exhibited metal ion-dependent ionochromic effects in their absorption and emission spectra [8–13] . These conjugated polymers have been found to be highly sensitive to a wide variety of metal ions, and their fluorescence is completely quenched or red/blue-shifted depending on the addition of different metal ions. In these sensory systems, factors such as the conformational changes in the backbone, the electron density and the electronic structures of metal ions need to be considered. Recently, great efforts have been focused on the design of tailored sensory materials to detect specific metal ions, owing to the important result by Wayne et al. that the conjugation of receptors to the polymer backbone is not required for the fluorescence response [13] . Polyfluorenes with imidazole [14] and phosphonate [15] groups in the side chain as chemosensors have been reported. These polymers with imidazole and phosphonate groups are highly sensitive and selective chemosensors for Cu 2+ and Fe 3+ ions, respectively. As a result, the development of tailored sensory materials for the sensitive and selective sense of metal ions could be realized through the appropriate alteration of receptors in the side chain and backbone structure of π-conjugated polymers. The 3-(pyridin-2-yl)-1 H -1,2,4-triazole and 2-(2′-pyridyl)-benzimidazole derivatives are important ligands, and the obtained metal complexes were often shown attractive chemical and physical properties [16,17] . Peter G. Pickup group successfully introduced 2-(2′-pyridyl)-benzimidazole into conjugated polymer backbone to form novel hybrid conjugated Ru and Os metallopolymers. 2-(2′-Pyridyl)-benzimidazole derivatives were also shown to be useful metal ion binding ligands in the self-assembly of supramolecular polymers and were widely used in the preparation of the Ru 2+ , Zn 2+ , and Fe 2+ metallo-supramolecular conjugated polymers. Triazole derivatives were shown to have more efficient electron-transport and hole-blocking characteristics than oxadiazole moiety in polymer light-emitting diodes [18] . In this paper, we report the novel polyfluorenes with 5-methyl-3-(pyridin-2-yl)-1,2,4-triazole and 2-(2′-pyridyl)-benzimidazole groups in the side chain and the sensing properties of some metal ions. To the best of our knowledge, it is the first report that 5-methyl-3-(pyridin-2-yl)-1,2,4-triazole and 2-(2′-pyridyl)-benzimidazole groups attached in the side chain of π-conjugated polymers are used as special receptors to detect metal ions. 2 Experimental section 2.1 Measurement and characterization 1 H and 13 C NMR spectra were recorded on a Bruker DRX 300 spectrometer in deuterated chloroform solution. GC–MS was recorded on a Trace 2000 Series (Finn igan Co.) with a quartz capillarity column (J&W DB-5MS: 30 m × 0.25 mm × 0.25 μm).The number-average ( M n ) and weight-average ( M w ) molecular weights of polymers were determined by a Waters GPC 2410 in tetrahydrofuran (THF) by using a calibration curve of polystyrene standards. Elemental analyses were performed on a Vario EL elemental analysis instrument (Elementar Co.). Cyclic voltammetry was carried out on a potentiostat/galvanostat model 283 (Princeton Applied Research) with platinum electrode at a scan rate of 50 mV/s against a saturated calomel electrode (SCE) with nitrogen-saturated solution of 0.1 M tetrabutylammonium hexafluorophosphate (Bu 4 NPF 6 ) in acetonitrile (CH 3 CN). 2.2 Fluorescence titration procedure The ion responsive properties of polymers were studied by using absorption and fluorescence emission spectroscopy in THF solution at a polymer concentration of 5.0 × 10 −6 M. Many kinds of metal ions, such as alkali, alkali earth, and transition metal ions were used in our experiment. Fluorescence spectra were obtained on Fluorometer (JY-FL-3). UV–vis absorption spectra were recorded on a HP 8453 spectrophotometer. Polymers' (P1–P4 ) concentration of 5 × 10 −6 M was based on the repeated units in the THF solution. Fluorescence titration was carried out by sequentially adding the cation aqueous solution of 0.2 M (0.02 M) to the polymer solution (10 ml) and stirred for 5 min prior to measuring fluorescence spectra. 2.3 Materials All manipulations involving air-sensitive reagents were performed under an atmosphere of dry argon. All reagents, unless otherwise specified, were obtained from Aldrich and Beida Syn Chem Co, and were used as received. 2.4 Monomers synthesis ( Scheme 1 ) 2.4.1 3,6-Dibromo-9-(6′-bromohexyl)-carbazole ( 1 ) To a solution of sodium hydride (2.47 g, 61.6 mmol, 60%) in dry THF (50 ml), 3,6-dibromocarbazole (10 g, 30.8 mmol) in dry THF (50 ml) was added dropwise. The mixture was refluxed for 1.5 h under N 2 atmosphere, and the resulted mixture was further added dropwise to 1,6-dibromohexane (90 mmol) in THF (10 ml). The reaction mixture was refluxed for another 24 h and then cooled to room temperature. It was extracted with dichloromethane followed by washing with water. The oil phase was separated and dried overnight with MgSO 4 . The solvent was removed by evaporation, and the crude product was purified by silica column chromatography to give 9.1 g of white solid (yield: 60%). 1 H NMR (CDCl 3 , 300 MHz, δ , ppm): 8.14 (d, 2H, J = 1.8 Hz, Cz–H), 7.52 (m, 2H), 7.20 (t, 2H, J 1 = 6.1 Hz, J 2 = 2.5 Hz, Cz–H), 4.23–4.21 (t, 2H, J 1 = 6.9 Hz, J 2 = 7.2 Hz, CzN–CH 2 ). 3.33–3.30 (m, 2H, Br–CH 2 ), 1.85–1.81 (m, 8H, CH 2 ) (aliphatic). 13 C NMR (CDCl 3 , 75 MHz, δ , ppm): 139.3, 129.0, 123.5, 123.3, 112.0, 110.3 (carbazole ring), 43.1 (N–CH 2 ), 33.6, 32.5, 28.7, 27.8, 26.4. Anal. Calcd for C 18 H 18 NBr 3 : C, 44.26; H, 3.70; N, 2.86. Found: C, 44.75; H, 3.83; N, 2.85. GC–MS (488, M + ). 2.4.2 1,4-Dibromo-2-methoxy-5-[(6′-bromo)hexyloxy]benzene ( 2 ) A solution of bromine (0.64 g, 4.1 mmol) in chloroform (50 ml) was slowly added to a solution of 1-(6′-bromo)hexyloxy-4-methoxy-benzene (7.3 g, 2 mmol) in chloroform (100 ml) at 0 °C. The mixture was stirred at room temperature for 24 h and was then neutralized by iced aqueous KOH. After washing with water, diluted hydrochloric acid solution and brine, the organic layer was dried overnight with MgSO 4 . Removal of the solvent followed by recrystallization from ethanol afforded a white solid (yield: 75%). 1 H NMR (CDCl 3 , 300 MHz, δ , ppm): 7.11 (s, 2H, Ar–H), 4.01–3.96 (t, 2H, J = 6.4 Hz, OCH 2 ), 3.87 (s, 3H, OCH 3 ), 3.47–3.43 (t, 2H, J = 7.1 Hz, Br–CH 2 ), 1.93–1.54 (m, 8H, CH 2 ) (aliphatic). 13 C NMR (CDCl 3 , 75 MHz, δ , ppm): 150.6, 150.1, 118.7, 117.0, 111.3, 110.4, 70.1, 57.0, 33.8, 32.7, 28.9, 27.8, 25.2. Anal. Calcd for C 13 H 17 O 2 Br 3 : C, 35.10; H, 3.82. Found: C, 35.13; H, 4.06. GC–MS (442, M + ). 2.4.3 2-(2′-Pyridyl)-benzimidazole ( 3 ) [16e] O -Phenylene diamine (40.0 mmol, 4.32 g) and picolinic acid (40.0 mmol, 4.92 g) were added to 100 ml of 85% polyphosphoric acid, and the mixture was then heated to 190 °C. After 8 h, the solution was cooled and added to 1000 ml of ice water. The solution was made alkaline (pH = 10, NaOH) and allowed to stir overnight. A purple/lavender precipitate was filtered and collected. Further purification to remove excess o -phenylene diamine was achieved by reprecipitation. The lavender precipitate was dissolved in 200 ml of sodium carbonate solution (10%) and stirred to dissolve all the material. The pH of the solution was brought from 11 to 7.8, resulting in the reprecipitation of the lavender product. The precipitate was collected by filtration and dried. The product was further purified by column chromatography and recrystallization to give a white solid (yield: 25%). M.p. 219 °C. 1 H NMR (CDCl 3 , 300 MHz, δ , ppm): 8.54 (d, 1H, J = 4.8 Hz, Py–H), 8.49 (t, 1H, J = 7.9 Hz, Py–H), 7.92–7.87 (m, 2H, Py–H), 7.39–7.26 (m, 4H, Ar–H). GC–MS (195, M + ). 2.4.4 6,7-Dimethyl-2-(2′-pyridyl)-benzimidazole ( 4 ) It was prepared according to the procedure of synthesizing 2-(2′-pyridyl)-benzimidazole (yield: 21%). 1 H NMR (CDCl 3 , 300 MHz, δ , ppm): 8.59 (d, 1H, J = 4.8 Hz, Py–H), 8.47 (d, 1H, J = 8.0 Hz, Py–H), 7.88–7.83 (m, 2H, Py–H), 7.28–7.36 (m, 2H, Ar–H), 2.35 (s, 6H, Ar–CH 3 ). 13 C NMR (CDCl 3 , 75 MHz, δ , ppm): 150.1, 148.8, 137.3, 132.7, 132.0, 124.2, 121.7, 112.0, 119.8, 20.4 (Ar–CH 3 ). 2.4.5 5-Methyl-3-(pyridin-2-yl)-1 H -1,2,4-triazole ( 5 ) [17b] Equimolar amounts of 2-cyanopyridine and hydrazine monohydrate were mixed and a small amount of ethanol was added to obtain a clear solution. After standing overnight at room temperature, the almost colorless crystals of 2-pyridinecarboxamidrazone could be filtered off. The product was washed with diethyl ether and dried in the air. The solid obtained was added to a mixture of acetic acid and acetic anhydride at 0 °C and the solution was stirred at room temperature for 2 h. The solution was then concentrated under vacuum and the resulting oil heated at 130 °C for 1 h. The solid obtained was purified by repeated crystallization from diisopropyl ether (yield: 50%). M.p. 163–165 °C. 1 H NMR (CDCl 3 , 300 MHz, δ , ppm): 14.2 (s, N–H), 8.69 (d, 1H, J = 4.3 Hz, Py–H), 8.15 (d, 1H, J = 7.9 Hz, Py–H), 7.80 (t, 1H, J 1 = 6.8 Hz, J 2 = 7.5 Hz, Py–H), 7.32 (t, 1H, J 1 = 5.2 Hz, J 2 = 7.0 Hz, Py–H), 2.49 (s, 3H, Me). 13 C NMR (CDCl 3 , 75 MHz, δ , ppm): 158.5, 156.5, 149.4, 147.4, 137.5, 124.5, 121.7, 13.3 (Me). 2.4.6 2,7-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-9,9-dioctylfluorene (monomer 1 ) [20] It was prepared following the published procedure and the obtained boronic ester was recrystallized from methanol to give a white solid product (yield: 50%). 1 H NMR (CDCl 3 , 300 MHz, δ , ppm): 7.81 (m, 2H), 7.76 (s, 2H), 7.72 (m, 2H) (fluorene ring), 1.97 (m, 4H), 1.37 (s, 24H, CH 3 ), 1.22–0.98 (m, 20H), 0.81 (t, J = 6.7 Hz, 6H), 0.54 (m, 4H) (aliphatic). 13 C NMR (CDCl 3 , 75 MHz, δ , ppm): 150.9, 144.3, 134.1, 129.3, 121.7, 119.8 (fluorene ring), 84.1, 55.6 (C 9 -fluorene ring), 40.5, 32.2, 30.3, 29.6, 25.3, 24.0, 23.0, 14.5 (aliphatic). Anal. Calcd for C 41 H 64 O 4 B 2 : C, 76.74; H, 10.04. Found: C, 76.43; H, 9.95. 2.4.7 3,6-Dibromo-9-( N -(2-(2′-pyridyl)-benzimidazole)-hexyl)-carbazole (monomer 2 ) A mixture of 3,6-dibromo-9-(6′-bromohexyl)-carbazole (4.88 g, 10 mmol), 2-(2′-pyridyl)-benzimidazole (1.95 g, 10 mmol), sodium hydroxide (0.44 g, 11 mmol), and dimethyl sulphoxide (30 ml) were stirred and heated at 130 °C for 24 h under argon atmosphere. It was subsequently poured into ice water (100 ml). It was extracted with dichloromethane followed by washing with water. The oil phase was separated and dried overnight with MgSO 4 . The solvent was evaporated and the obtained product was purified by silica gel column chromatography (petroleum ether:ethyl acetate = 2:1 as eluent) to give a white solid (yield: 43%). 1 H NMR (CDCl 3 , 300 MHz, δ , ppm): 8.54–8.52 (d, 1H, J = 4.8 Hz, Py–H), 8.43–8.40 (d, 1H, J = 7.9 Hz, Py–H), 8.15–8.14 (d, 2H, J = 1.8 Hz, Cz–H), 7.87–7.81 (m, 2H, Py–H), 7.54–7.51 (dd, 2H, J = 1.9 Hz, Cz–H), 7.39–7.28 (m, 4H, Ar–H), 7.22–7.19 (m, 2H, Cz–H), 4.80 (t, 2H, J = 7.3 Hz, BmN–CH 2 ), 4.20 (t, 2H, J = 7.0 Hz, CzN–CH 2 ), 1.88–1.33 (m, 8H, CH 2 ) (aliphatic). 13 C NMR (CDCl 3 , 75 MHz, δ , ppm): 150.6, 149.7, 148.5, 142.6, 139.2, 136.8, 136.5, 129.1, 124.7, 123.7, 123.7, 123.5, 122.6, 120.1, 112.0, 110.3, 110.1, 45.2 (BmN–CH 2 ), 43.1 (CzN–CH 2 ), 29.8, 28.7, 26.8, 26.5 (aliphatic). Anal. Calcd for C 30 H 26 N 4 Br 2 : C, 59.80; H, 4.32; N, 9.30. Found: C, 59.89; H, 4.50; N, 9.30. 2.4.8 3,6-Dibromo-9-( N -(6,7-dimethyl-2-(2′-pyridyl)-benzimidazole)-hexyl)-carbazole (monomer 3 ) It was prepared according to the procedure of synthesizing monomer 2 (yield: 50%). 1 H NMR (CDCl 3 , 300 MHz, δ , ppm): 8.51–8.50 (d, 1H, J = 4.8 Hz, Py–H), 8.52–8.34 (m, 1H, Py–H), 8.14–8.13 (d, 2H, J = 1.8 Hz, Cz–H), 7.85–7.6 (m, 2H, Py–H), 7.52–7.48 (dd, 2H, J = 1.8 Hz, Cz–H), 7.35–7.28 (m, 2H, Ar–H), 7.22–7.19 (m, 2H, Cz–H), 4.79–4.75 (t, 2H, J = 7.2 Hz, BmN–CH 2 ), 4.25–4.17 (t, 2H, J = 7.1 Hz, CzN–CH 2 ), 2.41 (m, 6H, Ar–CH 3 ), 1.85–1.24 (m, 8H, CH 2 ) (aliphatic). 13 C NMR (CDCl 3 , 75 MHz, δ , ppm): 151.0, 149.0, 148.4, 139.2, 136.7, 135.2, 132.6, 131.6, 129.0, 124.5, 123.4, 123.4, 123.3, 120.1, 112.0, 110.3, 110.2, 45.2 (BmN–CH 2 ), 43.1 (CzN–CH 2 ), 29.9, 28.7, 26.8, 26.5 (aliphatic), 20.8, 20.4 (Ar–CH 3 ). Anal. Calcd for C 32 H 30 N 4 Br 2 : C, 60.90; H, 4.76; N, 8.88. Found: C, 61.10; H, 4.86; N, 8.83. 2.4.9 3,6-Dibromo-9-( N -(5-methyl-3-(pyridin-2-yl)-1,2,4-triazole)-hexyl)-carbazole (monomer 4 ) It was prepared according to the procedure of synthesizing monomer 2 (yield: 54%). 1 H NMR: (CDCl 3 , 300 MHz, δ , ppm): 8.49–8.46 (d, 1H, J = 4.8 Hz, Py–H), 8.16–8.13 (m, 3H), 7.82–7.77 (m, 1H), 7.54–7.51 (m, 2H), 7.31–7.20 (m, 3H), 4.73–4.69 (t, 2H, J = 7.5 Hz, TazN–CH 2 ), 4.23–4.21 (t, 2H, J = 7.1 Hz, CzN–CH 2 ), 2.41 (s, 3H, Taz–CH 3 ), 1.85–1.23 (m, 8H, CH 2 ) (aliphatic). 13 C NMR (CDCl 3 , 75 MHz, δ , ppm): 159.3, 151.6, 148.8, 148.0, 139.3, 136.9, 129.0, 124.0, 123.3, 123.7, 123.5, 112.0, 110.3, 50.3 (TazN–CH 2 ), 43.2 (CzN–CH 2 ), 29.9, 28.7, 26.7, 26.2 (aliphatic), 13.9 (Taz–Me). Anal. Calcd for C 26 H 25 N 5 Br 2 : C, 55.03; H, 4.40; N, 12.35. Found: C, 55.08; H, 4.41; N, 12.44. 2.4.10 1,4-Dibromo-2-methoxy-5-[ N -(2-(2′-pyridyl)-benzimidazole)hexyloxy]benzene (monomer 5 ) It was prepared according to the procedure of synthesizing monomer 2 (yield: 65%). 1 H NMR (CDCl 3 , 300 MHz, δ , ppm): 8.71–8.69 (d, 1H, J = 4.7 Hz, Py–H), 8.44–8.41 (d, 1H, J = 8.0 Hz, Py–H), 7.84–7.81 (m, 2H, Py–H), 7.44–7.29 (m, 4H, J = 6.8 Hz, BmAr–H), 7.10–7.07 (d, 2H, J = 5.8 Hz, Ar–H), 4.89–4.84 (t, 2H, J = 7.4 Hz, BmN–CH 2 ), 3.90–3.87 (t, 2H, J = 6.3 Hz, OCH 2 ), 3.82 (s, 3H, OCH 3 ), 1.94–1.20 (m, 10H, CH 2 ). 13 C NMR (CDCl 3 , 75 MHz, δ , ppm): 150.7, 150.6, 150.1, 149.9, 148.7, 142.6, 136.8, 136.6, 124.7, 123.7, 123.3, 122.5, 120.1, 118.7, 117.0, 111.3, 110.4, 110.2, 70.1, 57.0, 45.3, 29.9, 28.9, 26.5, 25.6. Anal. Calcd for C 25 H 25 N 3 O 2 Br 2 : C, 53.67; H, 4.48; N, 7.51. Found: C, 53.64; H, 4.51; N, 7.35. 2.5 Polymer synthesis (general procedures of Suzuki polycondensation, taking P1 as an example) 2,7-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-9,9-dioctylfluorene (monomer 1 ) (632 mg, 1.0 mmol), 3,6-dibromo-9-( N -(2-(2′-pyridyl)-benzimidazole)-hexyl)-carbazole (monomer 2 ) (602 mg, 1.0 mmol) and tetrakis(triphenylphosphine)-palladium (5 mg) were dissolved in the mixture of toluene/THF (10 ml) and stirred for 0.5 h, and then Et 4 NOH aqueous solution (20%, 4 ml) was added. The mixture was heated to 100 °C and stirred for 2 days under argon atmosphere. Then the polymer was capped by adding 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-9,9-dioctylfluorene (100 mg) and stirred for 12 h, and then capped by bromobenzene (1 ml) followed by heating for another 12 h. The mixture was poured into stirred methanol (250 ml) to generate plenty of light-white precipitates. The solid was collected by filtration and then dissolved in toluene and washed with water. The careful reprecipitation procedure in acetone/methanol was repeated for several times. The polymer was further purified by washing with refluxing acetone in Soxhlet for 2–3 days. The light-white solid was dried under vacuum at room temperature. P1 (yield: 52%): 1 H NMR (CDCl 3 , 300 MHz, δ , ppm): 8.56–8.53 (m, 3H), 8.43–8.40 (d, 1H, J = 7.9 Hz, Py–H), 7.87–7.74 (m, 10H), 7.51–7.41 (m, 6H) (fluorene ring, carbazole ring and 2-(2′-pyridyl)-benzimidazole ring), 4.84 (b, 2H, BemN–CH 2 ), 4.38 (b, 2H, CzN–CH 2 ), 1.92 (b, 4H), 1.69–1.13 (m, 20H), 1.14–0.78 (m, 18H) (aliphatic). 13 C NMR (CDCl 3 , 75 MHz, δ , ppm): 151.7, 150.7, 149.8, 148.6, 142.7, 140.8, 140.3, 139.6, 136.7, 136.6, 133.1, 126.2, 125.6, 124.7, 123.7, 123.6, 123.3, 122.5, 121.6, 120.2, 119.9, 119.0, 110.1, 109.0 (fluorene, carbazole and 2-(2′-pyridyl)-benzimidazole ring), 68.0, 55.4 (C 9 -fluorene ring), 45.3 (BemN–CH 2 ), 40.7 (CzN–CH 2 ), 31.8, 30.1, 29.9, 29.3, 29.0, 27.0, 26.7, 25.6, 24.0, 22.6, 14.1 (aliphatic). Anal. Calcd for C 59 H 66 N 4 : C, 85.30; H, 7.95; N, 6.75. Found: C, 84.62; H, 8.14; N, 6.05. P2 (yield: 56%): 1 H NMR (CDCl 3 , 300 MHz, δ , ppm): 8.53–8.40 (m, 3H), 8.42–8.39 (d, 1H, J = 8.0 Hz, Py–H), 7.90–7.85 (m, 2H), 7.83–7.62 (m, 7H), 7.51–7.48 (d, 2H, J = 8.5 Hz), 7.28–7.20 (m, 3H) (fluorene ring, carbazole ring and 2-(2′-pyridyl)-benzimidazole ring), 4.82–4.81 (t, 2H, J 1 = 6.8 Hz, J 2 = 7.4 Hz, BmN–CH 2 ), 4.38–4.37 (m, 2H, CzN–CH 2 ), 2.44–2.42 (d, 6H, J = 6.8 Hz, BmAr–CH 3 ), 1.93–1.91 (m, 6H), 1.47–1.15 (m, 26H), 1.147–0.82 (m, 10H) (aliphatic). 13 C NMR (CDCl 3 , 75 MHZ, δ , ppm): 150.7, 149.8, 142.7, 136.7, 136.6, 124.7, 123.7, 123.3, 122.5, 120.2, 110.2 (2-(2′-pyridyl)-benzimidazole ring), 151.7, 148.6, 140.8, 140.3, 139.6, 133.1, 126.2, 125.6, 123.6, 121.6, 119.9, 119.0, 109.0 (fluorene and carbazole ring), 68.0, 55.4 (C 9 -fluorene ring), 45.2, 40.7, 31.8, 30.3, 30.1, 29.9, 29.7, 29.3, 29.1, 27.0, 23.9, 22.6, 20.8, 14.1 (aliphatic). Anal. Calcd for C 61 H 70 N 4 : C, 85.32; H, 8.16; N, 6.52. Found: C, 84.81; H, 8.33; N, 5.87. P3 (yield: 53%): 1 H NMR (CDCl 3 , 300 MHz, δ , ppm): 8.53–8.15 (m, 4H), 7.89–7.75 (m, 9H), 7.54–7.26 (m, 2H) (fluorene ring, carbazole ring and pyridine ring), 4.79–4.74 (t, 2H, J = 6.9 Hz, TazN–CH 2 ), 4.41 (b, 2H, CzN–CH 2 ), 2.46 (s, 3H, TazN–CH 3 ), 2.17–1.93 (m, 4H), 1.48–1.13 (m, 25H), 0.85–0.79 (m, 13H) (aliphatic). 13 C NMR (CDCl 3 , 75 MHz, δ , ppm): 159.4, 151.7, 151.6, 148.9, 148.0, 140.8, 140.4, 139.6, 136.9, 133.1, 126.2, 125.6, 123.9, 123.6, 121.6, 119.9, 119.0, 109.1, 68.0, 55.4 (C 9 -fluorene ring), 40.7, 31.8, 30.1, 30.0, 29.3, 29.1, 26.9, 26.3, 25.6, 23.9, 22.6, 14.1 (aliphatic), 13.9 (Taz–Me). Anal. Calcd for C 55 H 65 N 5 : C, 83.01; H, 8.17; N, 8.81. Found: C, 82.60; H, 8.30; N, 8.19. P4 (yield: 60%): 1 H NMR (CDCl 3 , 300 MHz, δ , ppm): 8.65–8.63 (d, 1H, J = 4.7 Hz, Py–H), 8.44–8.41 (d, 1H, J = 8.0 Hz, Py–H), 7.87–7.82 (m, 2H, Py–H), 7.79–7.42 (m, 5H, Ar–H), 7.42–7.14 (m, 8H, Ar–H), 4.84–4.81 (t, 2H, J 1 = 7.3 Hz, J 2 = 7.1 Hz, N–CH 2 ), 4.0–3.89 (m, 2H, OCH 2 ), 3.80 (s, 3H, OCH 3 ), 1.91–1.76 (m, 6H), 1.44–1.29 (m, 6H), 1.16–0.91 (m, 21H), 0.83–0.61 (m, 9H). 13 C NMR (CDCl 3 , 75 MHz, δ , ppm): 151.2, 150.8, 150.5, 149.8, 148.6, 142.7, 139.9, 137.1, 136.7, 136.6, 131.7, 128.0, 124.7, 123.7, 123.3, 122.5, 120.1, 119.4, 117.0, 115.5, 110.2, 69.8, 56.8, 55.0 (C 9 -fluorene ring), 45.3, 40.6, 32.2, 31.8, 30.3, 30.0, 29.4, 28.9, 26.5, 25.7, 24.1, 22.6, 14.1. Anal. Calcd for C 54 H 65 N 3 O 2 : C, 82.34; H, 8.26; N, 5.46. Found: C, 82.33; H, 8.33; N, 5.01. 3 Results and discussion 3.1 Synthesis and structure characterization The synthetic routes of monomers are shown in Scheme 1 . The monomer ( 1 ) 2,7-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-9,9-dioctylfluorene was prepared following the published procedure [20] and the obtained product was recrystallized from methanol to give a white solid in a yield of 50%. The monomer ( 2 ) 3,6-dibromo-9-( N -(2-(2′-pyridyl)-benzimidazole)-hexyl)-carbazole was synthesized by a coupling reaction between 2-(2′-pyridyl)-benzimidazole and 3,6-dibromo-9-(6′-bromohexyl)-carbazole in the presence of sodium hydroxide according to the published procedure [19] . The monomers ( 3 – 5 ) were obtained in the same way as a white solid. The polymers (P1–P4) were prepared from monomers 1  and 2 – 5 by using Suzuki polycondensation ( Scheme 2 ). The feed ratios of monomer 1 to monomers ( 2 – 5 ) are 50:50 and the corresponding polymers are respectively named P1, P2, P3 and P4. The actual ratio of fluorene to receptor in polymers calculated from the elemental analysis is close to the feed ratio as listed in Table 1 . Polymers are soluble in common organic solvents, such as chloroform, THF, toluene and xylene. The number-average molecular weight ( M n ) and polydispersity (PDI) of polymers (P1–P4) are summarized in Table 1 . 3.2 Optical properties UV–vis absorption spectra of polymers in solid film are depicted in Fig. 1 (a). The absorption peaks of polymers (P1–P3) around 346 nm can be assigned to the π–π ∗ transition of conjugated backbone. The absorption peak of P4 at 372 nm can be assigned to the π–π ∗ transition of conjugated backbone and the absorption peaked at 317 nm can be due to the pendant 2-(2′-pyridyl)-benzimidazole group by comparison with the absorption data of 2-( N -(2′-pyridyl)-hexyl)-benzimidazole, respectively. The absorption and emission data of polymers (P1–P4) are summarized in Table 2 . In comparison with P4 containing an almost linear conjugation chain structure, the blue shift (Δ λ = 30 nm) of absorption peaks of P1–P3 is probably attributed to their zigzag chain structure [22] . The carbazole at the 3,6-linkage can effectively decrease the conjugation length of polymer backbone. From the similarity in absorption and emission spectra of polymers (P1–P3), it is observed that the introduction of different receptors in the side chain has little effect on the conjugation length of polymer backbone. Being consistent with the absorption spectra, the emission peaks of polymers (P1–P3) show the blue shift (about Δ λ = 13 nm) compared with P4, which is a further evidence of the shorter conjugation length of the backbone. 3.3 Electrochemical properties The electrochemical characteristics of the polymer thin films coated on Pt electrode were investigated by cyclic voltammetry (CV). The highest occupied molecular orbital (HOMO) levels were calculated according to the empirical formula E HOMO = − e ( E ox + 4.4), where E ox is the onset oxidation potential vs. SCE. Because no reversible n-doping process was observed on the cyclic voltammograms, the LUMO levels were estimated from the HOMO values and values of optical band gaps ( E g opt ) by the empirical formula E LUMO = E HOMO + E g opt . The optical band gap was obtained from the equation E g opt = 1240 / λ edge , where λ edge is the onset value of absorption spectrum of solid film in long wavelength direction [20] . The electrochemical data of polymers are summarized in Table 2 . The carbazole-based polymers (P1–P3) with different functional groups attached at the side chain have similar HOMO and LUMO levels. The HOMO levels increase and the LUMO levels of polymers (P1–P3) decrease compared with polyfluorene (PFO), owing to the introducing of the electron-rich carbazole moiety on the backbone [21,22] . 3.4 Responsive properties on metal ions and H + Polymers had no response upon addition of alkali and alkaline earth metal ions (up to 100 ppm) for absorption and fluorescence spectra due to the poor coordination ability of the receptors with these metal ions. No obvious change in the absorption spectra upon the addition of transition metal ions (up to 100 ppm) was observed, which was not as apparent as that of those materials containing acceptors directly in conjugated main chain, because the interaction of metal ions with receptors in the side chain had little effect on the electronic structure of the backbone [14] . The influences of various metal ions on the fluorescence emission response of the polymers are shown in Table 3 . Ni 2+ , Co 2+ , Ag + and Fe 3+ ions caused complete fluorescent quenching of all polymers, which was tentatively attributed to the energy or electron-transfer reactions between the polymer backbone and binding metal complexes in the side chain [15] . Cu 2+ ion hardly quenched the fluorescence of all polymers even at a high concentration (100 ppm). However, for those oligopyridyl-functionalized conjugated polymers, the fluorescence could be completely quenched by Cu 2+ at a very low concentration [8–13] . Such distinct ion responsive behaviors revealed the obvious difference of coordination abilities of Cu 2+ between 2-(2′-pyridyl)-benzimidazole and 5-methyl-3-(pyridin-2-yl)-1,2,4-triazole, and oligopyridine receptors. As a result, the development of tailored sensory materials for selectively sensing of metal ions could be realized through appropriate alteration of receptors with various degrees of affinity toward metal ions [14] . The same result was observed by Mn 2+ ion ( Table 3 ). The responsive selectivities of P4 to metal ions are depicted in Fig. 2 and Table 3 . The tested metal ions could be categorized into three groups according to the data of ( I 0 / I ): (1) Cd 2+ , Pb 2+ , Zn 2+ , Cu 2+ and Mn 2+ , slightly quenched; (2) Al 3+ , Ag + , Co 2+ , Sn 2+ and Ni 2+ , efficiently quenched; (3) Fe 3+ , completely quenched. A Stern–Volmer fluorescence quenching analysis by Ni 2+ ion in the P1 and P4 solutions is shown in Fig. 3 . The concentrations of polymers were fixed at 5.0 × 10 −6 M corresponding to receptor units. The polymers (P1 and P4) used 2-(2′-pyridyl)-benzimidazole unit as a receptor with the different backbone and P4 has longer conjugation length in comparison with P1 (see Fig. 1 ). P1 was more sensitive to Ni 2+ ion compared with P4. The fluorescence of P1 was quenched to 50 ( I 0 / I ) upon the addition of a Ni 2+ solution of 3.2 × 10 −6 M, whereas the fluorescence of P4 was only quenched to 22 ( I 0 / I ) in a Ni 2+ solution of 5.0 × 10 −6 M. Based on Fig. 3 , the corresponding Stern–Volmer constants ( K sv ) were calculated at 1.7 × 10 7 and 4.05 × 10 6 for P1 and P4, respectively. The observed higher K sv of P4 suggested that the backbone structure and the efficiencies of energy or electron transfer between backbone and receptor ions in the side chain play important roles in fluorescence quenching [4] . The effects of the chelating ability of the 2-(2′-pyridyl)-benzimidazole and 6,7-dimethyl-2-(2′-pyridyl)-benzimidazole groups in polymers on the fluorescence quenching properties were investigated ( Fig. 3 ). There was no obvious difference in the ion sensitivity between P1 and P2 in the low Ni 2+ concentrations. However, the receptor-dependent response of the polymers to Al 3+ was obvious between P2 and P3, containing different receptors in the side chain and the same conjugated backbone. The fluorescence of P2 was quenched to 262 ( I 0 / I ) whose quenching ratio was above 99.7% upon the addition of a Al 3+ solution of 1 × 10 −4 M, while the fluorescence of P3 was quenched only to 3.2 ( I 0 / I ) in the same concentration ( Table 3 ). The receptor-dependent response of the polymers to Sn 2+ was also obvious. The fluorescence of P3 was hardly quenched by Sn 2+ ion, whereas the fluorescence of P2 was efficiently quenched. There was poor selectivity of P2 to metal ions when the quencher concentration was as high as 100 ppm. However, P2 showed good selectivity to Ni 2+ when the quencher concentration was as low as 5 ppm, probably owing to the different chelating ability of receptor with ion [9] . The fluorescence was quenched to 1% of its initial intensity in the presence of Ni 2+ , while the quenching was hardly observed in the presence of Fe 3+ , Al 3+ , Pb 2+ , Zn 2+ , Cu 2+ , Ag + , Sn 2+ and Mn 2+ ions in the same condition, as shown in Fig. 4 . A Stern–Volmer fluorescence quenching analysis of P4 by the formic acid in different solution is shown in Fig. 5 . The emission obviously decreased in chloroform solution and hardly changed in THF solution in the range of H + concentration from 0 to 0.15 M. The decreased quenching effect should be attributed to the hydrogen-bonding interactions between the THF and formic acid molecules [23] . The hydrogen-bonding effect weakens the interactions between the receptors and the analytes, which was also observed in polyfluorenes with phosphonate groups in the side chain as chemosensors for sensing Fe 3+ [15] . The similar results were also shown by other polymers (P1–P3) (not listed). 4 Conclusions The fluorescences of polymers (P1–P4) were efficiently quenched upon the transition metal ions such as Co 2+ , Ni 2+ , Fe 3+ and Ag + due to the enhanced electronic communication properties of the conjugated polymers. The fluorescences of P1 and P4 were quenched to 50 ( I 0 / I ) and to 22 ( I 0 / I ) upon the addition of a Ni 2+ solution of 3.2 × 10 −6 M, as well as 5.0 × 10 −6 M, respectively, owing to the different conjugated backbone. The fluorescences of P2 and P3 were completely and hardly quenched, respectively, upon the addition of a Al 3+ solution of 1.0 × 10 −4 M, owing to the different receptors in the side chain. P2 showed good selectivity to Ni 2+ in the range of quencher concentration as low as 5 ppm, owing to the different chelating ability of receptor with ion. Cu 2+ and Mn 2+ ions hardly quenched the fluorescences of polymers (P1–P4), which was different from the oligopyridyl-functionalized conjugated polymers. It was demonstrated that the polymers containing 2-(2′-pyridyl)-benzimidazole and 5-methyl-3-(pyridin-2-yl)-1,2,4-triazole groups might act as promising active materials for application as fluorescent chemosensors. 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Chi Y.S. Yeh Inorg Chem 45 2006 137 [18] L.S. Yu S.A. Chen Adv Mater 16 2004 744 [19] F.S. Liang Q.G. Zhou Y.X. Cheng L.X. Wang D.G. Ma X.B. Jing Chem Mater 15 2003 1935 [20] M. Ranger D. Rondeau M. Leclerc Macromolecules 30 1997 7686 [21] J.L. Bredas R. Sibey D.S. Boudreaux R.R. Chance J Am Chem Soc 105 1983 6555 [22] (a) B. Liu W. Yu Y. Lai W. Huang Chem Mater 13 2001 1984 (b) T. Liu J.S. Gao B.H. Xia X. Zhou H.X. Zhang Polymer 48 2007 502 (c) Y.Q. Fu Z.S. Bo Macromol Rapid Commun 26 2005 1704 (d) J.P. Lu Y. Tao M. D'iorio Y.N. Li J.F. Ding M. Day Macromolecules 37 2004 2442 [23] S.P. Economopoulos A.K. Andreopoulou V.G. Gregoriou J.K. Kallitsis Chem Mater 17 2005 1063",
        "keywords": [
            "fluorescent chemosensor",
            "polyfluorene",
            "responsive property",
            "metal ion",
            "fluorescence",
            "transition metal",
            "suzuki coupling",
            "absorption spectrum"
        ],
        "authors": [
            {
                "name": "Bin Du",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology, Key Lab of Special Functional Materials, Ministry of Education, Wushan Road, Guangzhou 510640, Guangdong, China"
            },
            {
                "name": "Ransheng Liu",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology, Key Lab of Special Functional Materials, Ministry of Education, Wushan Road, Guangzhou 510640, Guangdong, China"
            },
            {
                "name": "Yong Zhang",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology, Key Lab of Special Functional Materials, Ministry of Education, Wushan Road, Guangzhou 510640, Guangdong, China"
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Wenbin Sun",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology, Key Lab of Special Functional Materials, Ministry of Education, Wushan Road, Guangzhou 510640, Guangdong, China"
            },
            {
                "name": "Mingliang Sun",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology, Key Lab of Special Functional Materials, Ministry of Education, Wushan Road, Guangzhou 510640, Guangdong, China"
            },
            {
                "name": "Junbiao Peng",
                "org": ""
            },
            {
                "name": "Yong Cao",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology, Key Lab of Special Functional Materials, Ministry of Education, Wushan Road, Guangzhou 510640, Guangdong, China"
            }
        ],
        "venue": "Polymer",
        "year": 2007
    },
    "7GpbWxbF": {
        "id": "7GpbWxbF",
        "title": "Fluorene-Based Single-Chain Copolymers for Color-Stable White Light-Emitting Diodes",
        "abstract": "",
        "keywords": [
            "2",
            "3-dimethyl-5",
            "8-dithien-2-ylquinoxaline",
            "9",
            "9-dioctyl-fluorene",
            "light-emitting diodes (led)",
            "structure",
            "white light-emitting diodes"
        ],
        "authors": [
            {
                "name": "Mingliang Sun",
                "org": ""
            },
            {
                "name": "Qiaoli Niu",
                "org": ""
            },
            {
                "name": "Bin Du",
                "org": ""
            },
            {
                "name": "Junbiao Peng",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Yong Cao",
                "org": ""
            }
        ],
        "venue": "Macromolecular Chemistry and Physics",
        "year": 2007
    },
    "u27vheaV": {
        "id": "u27vheaV",
        "title": "Novel light-emitting electrophosphorescent copolymers based on carbazole with an Ir complex on the backbone",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Hongyu Zhen",
                "org": ""
            },
            {
                "name": "Jie Luo",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Qiliang Chen",
                "org": ""
            },
            {
                "name": "Lei Ying",
                "org": ""
            },
            {
                "name": "Zou Jianhua",
                "org": ""
            },
            {
                "name": "Hongbin Wu",
                "org": ""
            },
            {
                "name": "Yong Cao",
                "org": ""
            }
        ],
        "venue": "Journal of Materials Chemistry",
        "year": 2007
    },
    "IWzIgLBZ": {
        "id": "IWzIgLBZ",
        "title": "An extended morphological stability model for a planar interface incorporating the effect of nonlinear liquidus and solidus",
        "abstract": "",
        "keywords": [
            "non-equilibrium",
            "nonlinear",
            "si-sn alloy",
            "stability",
            "phase diagram"
        ],
        "authors": [
            {
                "name": "Haifeng Wang",
                "org": ""
            },
            {
                "name": "Feng Liu",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Zheng Chen",
                "org": ""
            },
            {
                "name": "Gencang Yang",
                "org": ""
            },
            {
                "name": "Yaohe Zhou",
                "org": ""
            }
        ],
        "venue": "Acta Materialia",
        "year": 2008
    },
    "bSJSp97l": {
        "id": "bSJSp97l",
        "title": "Triphenylamine and Fluorene Based Cationic Conjugated Polyelectrolytes: Synthesis and Characterization",
        "abstract": "",
        "keywords": [
            "quenching"
        ],
        "authors": [
            {
                "name": "Wei Shi",
                "org": ""
            },
            {
                "name": "Xi Jiang",
                "org": ""
            },
            {
                "name": "Wenjin Zen",
                "org": ""
            },
            {
                "name": "Fei Huang",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Ransheng Liu",
                "org": ""
            },
            {
                "name": "Yong Cao",
                "org": ""
            }
        ],
        "venue": "Macromolecular Chemistry and Physics",
        "year": 2008
    },
    "sCtYbnVW": {
        "id": "sCtYbnVW",
        "title": "Molecular design of efficient white-light-emitting fluorene-based copolymers by mixing singlet and triplet emission",
        "abstract": "",
        "keywords": [
            "conjugated polymers",
            "light-emitting diodes (led)",
            "molecular design",
            "polyfluorene",
            "singlet",
            "synthesis",
            "triplet",
            "white-light emission"
        ],
        "authors": [
            {
                "name": "Yunhua Xu",
                "org": ""
            },
            {
                "name": "Rong Guan",
                "org": ""
            },
            {
                "name": "Jiaxing Jiang",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Hongyu Zhen",
                "org": ""
            },
            {
                "name": "Junbiao Peng",
                "org": ""
            },
            {
                "name": "Yong Cao",
                "org": ""
            }
        ],
        "venue": "Journal of Polymer Science Part A-polymer Chemistry",
        "year": 2008
    },
    "BujbIQ5S": {
        "id": "BujbIQ5S",
        "title": "Efficient Single Active Layer Electrophosphorescent White Polymer Light‐Emitting Diodes",
        "abstract": "",
        "keywords": [
            "light emitting diodes",
            "light emitting diode"
        ],
        "authors": [
            {
                "name": "hao bin wu",
                "org": "south china university of technology"
            },
            {
                "name": "j h zou",
                "org": "south china university of technology"
            },
            {
                "name": "fuken liu",
                "org": "south china university of technology"
            },
            {
                "name": "lizhen wang",
                "org": "south china university of technology"
            },
            {
                "name": "alexander a mikhailovsky",
                "org": "university of california santa barbara"
            },
            {
                "name": "guillermo c bazan",
                "org": "university of california santa barbara"
            },
            {
                "name": "w yang",
                "org": "south china university of technology"
            },
            {
                "name": "yun cao",
                "org": "south china university of technology"
            }
        ],
        "venue": "Advanced Materials",
        "year": 2008
    },
    "kpNSgwB9": {
        "id": "kpNSgwB9",
        "title": "Synthesis and properties of copolymers based on dialkylfluorene and 3, 6-fluorene substituted by triphenylamine units",
        "abstract": "A series of conjugated copolymers derived from 9, 9-dioctyl-2, 7-fluorene (DOF) and 9, 9-bis (4-di-phenylaminophenyl)-3, 6-fluorene (36FT) were prepared by Suzuki coupling polymerization, which have a high molecular weights (Mn = 47000-189000). The resulting copolymers are readily soluble in common organic solvents such as THF, CHCl3 and toluene etc.. The electrochemical, optical and electroluminescent properties were investigated. Cyclic voltammogram (CV) indicates that the HOMO level of the copolymers is higher than that of the PF homopolymer, and it increases with the increase in 36FT mass fraction from 2% to 35%. The blue polymer light-emitting diodes (PLEDs) with the device configuration of ITO/PEDOT/PVK/ polymer/Ba/Al were prepared. The highest external quantum efficiency was 0.52% from the device with 36PFT10 as the active layer.",
        "keywords": [
            "Electroluminescence",
            "Poly (fluorene) derivatives",
            "Polymer light-emitting diodes (PLEDs)"
        ],
        "authors": [
            {
                "name": "WU Zhong-Lian",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Lei Wang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "LIU Jin-Cheng",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Lei Ying",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Wei Yang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Yong Cao",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            }
        ],
        "venue": "Gaodeng Xuexiao Huaxue Xuebao/Chemical Journal of Chinese Universities",
        "year": 2008
    },
    "8FVcGzgM": {
        "id": "8FVcGzgM",
        "title": "Highly efficient and spectrally stable blue-light-emitting polyfluorenes containing a dibenzothiophene-S,S-dioxide unit",
        "abstract": "Spectrally stable blue-light-emitting polyfluorenes with high efficiency were realized via incorporating dibenzothiophene-,S,S,-dioxide (SO) isomer (3,7-diyl or 2,8-diyl) into the poly[9,9-bis(4-(2-ethylhexyloxy)phenyl)fluorene- 2,7-diyl] (PPF) backbone. The resulting polymers have high fluorescence yield and exhibit very good thermal stability. The EL spectra of all copolymers remain almost unchanged, and no green emission is observed even at high applied current density (more than 360 mA/cm2) or high annealing temperature(∼200 °C). With the device configuration ITO/PEDOT:PSS/PVK/ emissive layer/Ba/Al, a maximum luminous efficiency (LE) of 6.0 cd/A (corresponding to an external quantum efficiency (EQE) of 5.5%) at 69 mA/cm 2 with CIE coordinates of (0.16,0.19) for the polymer PPF-3,7SO20 and a maximum LE of 3.3 cd/A (EQE = 4.2%) with CIE coordinates of (0.16, 0.08) for the polymer PPF-2,8SO5 were obtained, respectively. The results indicate that this approach is very promising to obtain spectrally stable blue-light-emitting polyfluorenes with high efficiency. © 2008 American Chemical Society.",
        "keywords": [],
        "authors": [
            {
                "name": "Jie Liu",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Jianhua Zou",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Wei Yang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Hongbin Wu",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Chun Li",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Bin Zhang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Junbiao Peng",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Yong Cao",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            }
        ],
        "venue": "Chemistry of Materials",
        "year": 2008
    },
    "PmEmwiIU": {
        "id": "PmEmwiIU",
        "title": "Novel red light-emitting polymers based on 2,7-carbazole and thiophene derivatives",
        "abstract": "A series of conjugated copolymers derived from 9-ethylhexyl-2,7-carbazole (Cz) and 4,7-di(4-hexylthien-2-yl)-2,1,3-benzothiadiazole (DHTBT) was synthesized by Suzuki polycondensation. The photo- and electro-luminescent properties of these polymers were investigated. Efficient energy transfer from the Cz segment to the DHTBT unit occurs even if the DHTBT content as low as 1 mol%. PL emission was red-shifted significantly from 645 nm to 700 nm with the increase in DHTBT content by 150 mol%. PL efficiencies decreased with the increase in DHTBT content in the polymers from 55% for PCzDHTBT1 gradually down to 7% for PCzDHTBT50. EL emission of these polymers red-shifted from 640 nm to 690 nm when the DHTBT content increased from 1 mol% to 50 mol%. The highest external quantum efficiency was 1.67% for PCzDHTBT25 with the maximum luminescence of 870 cd/m2 in the device configuration of ITO/PEDOT:PSS/polymer/PFN/Ba/Al. The enhancement of device performances could be due to the improved electron injection by inserting the amino-containing polyfluorene (PFN) layer. These polymers are promising candidates as a red emitter in the full-color polymer light emitting diodes (PLEDs). © 2008 World Scientific Publishing Company.",
        "keywords": [
            "2",
            "7-carbazole",
            "red light-emitting polymer",
            "thiophene derivatives"
        ],
        "authors": [
            {
                "name": "Ransheng Liu",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "WenJin Zeng",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Bin Du",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Wei Yang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Qiong Hou",
                "org": "South China Normal University(South China Normal University),Guangzhou,China"
            },
            {
                "name": "Wei Shi",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Yong Zhang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Yong Cao",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            }
        ],
        "venue": "Chinese Journal of Polymer Science (English Edition)",
        "year": 2008
    },
    "QeyF8LYK": {
        "id": "QeyF8LYK",
        "title": "High-Triplet-Energy Poly(9,9′-bis(2-ethylhexyl)-3,6-fluorene) as Host for Blue and Green Phosphorescent Complexes",
        "abstract": "",
        "keywords": [
            "electroluminescence",
            "polymers"
        ],
        "authors": [
            {
                "name": "Zhonglian Wu",
                "org": ""
            },
            {
                "name": "Yan Xiong",
                "org": ""
            },
            {
                "name": "Jianhua Zou",
                "org": ""
            },
            {
                "name": "Lei Wang",
                "org": ""
            },
            {
                "name": "Jincheng Liu",
                "org": ""
            },
            {
                "name": "Qiliang Chen",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Junbiao Peng",
                "org": ""
            },
            {
                "name": "Yong Cao",
                "org": ""
            }
        ],
        "venue": "Advanced Materials",
        "year": 2008
    },
    "YGMWviiR": {
        "id": "YGMWviiR",
        "title": "Highly Efficient and Spectrally Stable Blue-Light-Emitting Polyfluorenes Containing a Dibenzothiophene-<i>S</i>,<i>S</i>-dioxide Unit",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Jie Liu",
                "org": ""
            },
            {
                "name": "Jianhua Zou",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Hongbin Wu",
                "org": ""
            },
            {
                "name": "Chun Li",
                "org": ""
            },
            {
                "name": "Bin Zhang",
                "org": ""
            },
            {
                "name": "Junbiao Peng",
                "org": ""
            },
            {
                "name": "Yong Cao",
                "org": ""
            }
        ],
        "venue": "Chemistry of Materials",
        "year": 2008
    },
    "BxQM2bYn": {
        "id": "BxQM2bYn",
        "title": "Amino-containing saturated red light-emitting copolymers based on fluorene and carbazole units",
        "abstract": "Amino-containing copolymers were synthesized by Suzuki polycondensation based on 9,9-di(2-ethylhexy)fluorene, 9-dimethylaminopropyl carbazole and 4,7-di(4-hexyl-2-thienyl)-2,1,3-benzothiadiazole (≤15 mol%) units. The copolymers had high glass-transition temperature ( T g s: 86–145 °C), excellent thermal stability ( T d (5% loss) : 400 °C) and emitted red light at 658 nm. The peak was shifted from 614 to 658 nm when the 4,7-di(4-hexyl-2-thienyl)-2,1,3-benzothiadiazole content was increased from 0.1 to 15 mol%. The dimethylaminopropyl group in the side chain of the copolymer significantly lowered the barrier height of the interface between the metal cathode and the polymer. Thus, aluminium can be used as the cathode in polymer light-emitting devices and operated at a level of performance similar to that achieved with metal cathodes such as barium. Keywords Fluorene Amino-containing carbazole Copolymers Red emission Al cathode 1 Introduction Polymer light-emitting devices (PLEDs) have received remarkable scientific and industrial attentions due to their potential applications in large area flat-panel displays [1–3] . During the past decades, a variety of conjugated polymers have been synthesized in order to identify promising candidates for high-resolution, full color, flat-panel displays [4–6] . Polyfluorenes (PFs) and their derivatives have emerged as a promising class of light-emitting conjugated polymers because of their high photoluminescent (PL) and electroluminescent (EL) yields as well as easy tenability of physical properties through chemical structure modification and/or copolymerization [7–9] . The emission color of polyfluorenes also can be tuned over entire visible region by incorporating narrow-band gap co-monomers into polyfluorene backbone [10–12] . Red light-emitting polyfluorene was first synthesized by alternating copolymerization of fluorene and 4,7-dithienyl-2,1,3-benzothiadiazole (DBT) [13] , after which, a series of saturated red-emitting copolymers were synthesized by using different co-monomers such as qunquethithiphene-1″,1″-dioxide [14,15] , 2,5-bis(2′-vinyl-thienyl) thiophene [16] , and 2,1,3-naphthoselenadiazole [17] . It is well known that good electron and hole injections are necessary to obtain highly efficient PLEDs [18,19] . Recently, Huang et al. reported the amino-containing polyfluorene-based conjugated polymers with a small amount of narrow-band gap (NBG) co-monomers such as 2,1,3-benzothiazole [20] in the polymer main chain, and found that these kinds of polymers could provide good device performance by using a high-work-function metal such as Al, Ag, Au as the cathode, due to interface dipole formation between the light-emitting polymer and the high-work-function cathode [21] . Carbazole-based copolymers have good hole-injection properties due to the electron-donating capabilities associated with the nitrogen in carbazole unit [22–27] . Therefore, the incorporation of carbazole unit into the polymer chain will effectively raise the highest occupied molecular orbital (HOMO) energy levels and reduce the barrier height for hole injection between the anode or anode buffer layer and the light-emitting layer in PLEDs. In this paper, with the purpose of utilizing high-work-function metal as cathode and more effectively reducing the barrier height for hole injection, aminoalkyl group containing carbazole unit was employed since it can facilitate electron and hole injection simultaneously. The copolymers based on fluorene, containing aminoalkyl group carbazole (CzN) and 4,7-di(4-hexyl-2-thienyl)-2,1,3-benzothiadiazole (DHTBT) units were synthesized and investigated. 2 Experimental part 2.1 Materials All reagents, unless otherwise specified, were purchased from Aldrich and Acros, and were used as received. All solvents were carefully dried and purified under nitrogen flow. All manipulations involving air-sensitive reagents were performed in a dry argon atmosphere. The monomer 2,7-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-9,9-di(2-ethylhexyl)-fluorene ( 1 ) was synthesized according to published procedure [28] . 2.2 Instrumentations The 1 H and 13 C NMR spectra were recorded on a Bruker DRX 300 in deuterated chloroform solution. The number-average molecular weights ( M n ) were determined by a Waters GPC 2410 in tetrahydrofuran (THF) with a calibration curve of polystyrene standards. Elemental analyses were performed on a Vario EL elemental analysis instrument (Elementar Co.). UV–vis absorption spectra were recorded on an HP 8453 UV–vis spectrophotometer. Cyclic voltammetry was carried out on a CHI660A electrochemical workstation in a solution of tetrabutylammonium hexafluorophosphate (Bu 4 NPF 6 , 0.1 M) in acetonitrile (CH 3 CN) at a scanning rate of 50 mV/s at room temperature under argon. A platinum electrode coated with a thin polymer film was used as the working electrode. A Pt plate was used as the counter electrode and a saturated calomel electrode was used as the reference electrode. The thermogravimetric analysis (TGA) of the polymers was performed at a heating rate of 20 °C/min with a NETZSCH TGA-209 thermal analyzer under nitrogen atmosphere. The thermal transitional properties of the polymers were measured with a NETZSCH DSC-204 differential scanning calorimeter (DSC) under a nitrogen atmosphere at a heating rate of 10 °C/min. The photoluminescence (PL) efficiencies were determined in an IS080 integrating sphere (Labsphere) with 325 nm excitation of a HeCd laser (Mells Griot). PL and EL spectra were recorded on an Instaspec IV CCD spectrophotometer (Oriel Co.). 2.3 Synthesis of 3,6-dibromo-9-dimethylamiopropylcarbazole ( 2 ) 3,6-Dibromocarbazole (9.75 g, 30 mmol), NaH (0.96 g, 40 mmol) and 100 mL THF were added to a three-necked flask and stirred at room temperature for 2 h under a nitrogen atmosphere. 3-Dimethylaminopropyl chloride hydrochloride (11.0 g, 70 mmol) and NaOH (3.0 g, 75 mmol) were first diluted in 20 mL water and cooled, then the upper layer of solution was added dropwise to the above mixture. The reaction mixture was refluxed for an additional 24 h. After the removal of the solvent under a reduced pressure, the residue was purified by column chromatography on silica gel using petroleum ether/ethyl acetate/triethylamine (v/v = 20:5:1) as eluent. Recrystallization from ethanol gave the compound (yield: 88%) as white solid, mp: 118–119 °C. 1 H NMR (300 MHz, CDCl 3 ) δ (ppm): 8.12 (d, J = 1.89 Hz, 2H), 7.54 (dd, J 1 = 1.89 Hz, J 2 = 8.70 Hz, 2H), 7.35 (d, J = 8.70 Hz, 2H) (carbazole ring), 4.33 (t, J = 6.66 Hz, 2H, carbazole–N–CH 2 –), 2.20 (s, 6H, –N–CH 3 ), 2.18 (t, J = 3.72 Hz, 2H, –N–CH 2 –), 1.97 (m, 2H, –CH 2 –). 13 C NMR (75 MHz, CDCl 3 ) δ (ppm): 139.44, 129.01, 123.45, 123.18, 112.00, 110.61 (carbazole rings), 56.14 (carbazole–N–CH 2 –), 45.39 (–N–CH 2 –), 40.70 (–N–CH 3 ), 26.79 (alkyl, –CH 2 –). Element Anal. Calcd for C 17 H 18 Br 2 N 2 : C, 49.78%; H, 4.42%; N, 6.83%. Found: C, 49.80%; H, 4.46%; N, 6.80%. 2.4 Synthesis of 4,7-bis(5-bromo-4-hexyl-2-thienyl)-2,1,3-benzothiadiazole ( 3 ) [29–31] To a solution of 3-hexylthiophene in anhydrous THF at −30 °C, n -BuLi was added dropwise and the mixture was stirred at the same temperature under N 2 for 2 h. Then tributylchlorostannane was added, and the mixture was stirred at −30 °C for 30 min. The mixture was poured into saturated aqueous sodium hydrogen carbonate, and the organic phase was separated and washed with saturated aqueous brine and then dried over an anhydrous sodium sulfate. The solvent was removed under a reduced pressure, and the residue was purified by column chromatography on neutral alumina using petroleum ether as eluent to give tributyl-(4-hexyl-2-thienyl)stannane as colorless oil. The PdCl 2 (PPh 3 ) 2 was added to a solution of 4,7-dibromo-2,1,3-benzothiadiazole and tributyl-(4-hexyl-2-thienyl)stannane in THF. The mixture was refluxed in a nitrogen atmosphere for 6 h. After the removal of the solvent, the residue was purified by column chromatography on silica gel using petroleum ether/dichloromethane (v/v = 1:1) as eluent. Recrystallization from ethanol gave the compound 4,7-di(4-hexyl-2-thienyl)-2,1,3-benzothiadiazole as orange needles, which were dissolved into THF solution. After the solid dissolved completely, N -bromosuccinimide (NBS) was added in one portion. The mixture was stirred at a room temperature for 2 h, then the hexane was added into the mixture. The white precipitate formed was filtered off and the filtrate was extracted with ether. The organic phase were combined and washed with brine and dried over anhydrous sodium sulfate. The solvent was removed at a reduced pressure to give the product as a red solid (yield: 82%), mp: 102–103 °C. 1 H NMR (300 MHz, CDCl 3 ) δ (ppm): 7.75 (s, 2H, benzothiadiazole ring), 7.70 (s, 2H, thiophene rings), 2.63 (t, J = 7.50 Hz, 4H, –CH 2 –), 1.71–1.62 (m, 4H, –CH 2 –), 1.43–1.25 (m, 12H, –CH 2 –), 0.93–0.89 (m, 6H, –CH 3 ). 13 C NMR (75 MHz, DCl 3 ) δ (ppm): 152.20, 143.07, 138.49, 128.06, 125.27, 124.81, 111.62 (aryl rings), 31.66, 29.76, 29.70, 28.99, 22.64, 14.13 (alkyl chain). Element Anal. Calcd for C 26 H 30 N 2 S 3 Br 2 : C, 49.84%; H, 4.83%; N, 4.47%; S, 15.35%. Found: C, 50.58%; H, 5.06%; N, 4.37%; S, 14.86%. 3 Polymerization General procedures of Suzuki polycondensation taking PFCzN–DHTBT1 as an example: 2,7-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-9,9-di(2-ethylhexyl)-fluorene ( 1 ) (0.642 g, 1 mmol), 3,6-dibromo-9-dimethylaminopropylcarbazole ( 2 ) (0.4018 g, 0.98 mmol), 4,7-bis(5-bromo-4-hexyl-2-thienyl)-2,1,3-benzothiadiazole ( 3 ) (0.0125 g, 0.02 mmol), and (PPh 3 ) 4 Pd(0) (8 mg) were dissolved in 10 mL mixture of toluene/THF (2:1(v/v)) and 2 mL of 2 M Na 2 CO 3 aqueous solution. The mixture was refluxed with vigorous stirring for 3 days under argon. Then 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-9,9-di(2-ethylhexyl)fluorene (0.064 g) and bromobenzene(0.4 mL) were added and continue reaction for 12 h, respectively. The whole mixture was poured into methanol. The resulted solid was filtered and washed for 24 h with mixture solution acetone/water to remove oligomers and catalyst residues. Yield: 70%. PFCzN–DHTBT1: 1 H NMR (300 MHz, CDCl 3 ) δ (ppm): 8.44 (s, 2H), 7.85–7.72 (m, 8H), 7.60–7.57 (m, 2H) (aryl rings), 4.49 (br s, 2H, carbazole–N–CH 2 –), 2.38–2.16 (m, 16H), 0.94–0.59 (m, 35H) (alkyl chain). Element Anal. Found: C, 84.36%; H, 9.01%; N, 3.78%; S, 0.43%. PFCzN–DHTBT5: 1 H NMR (300 MHz, CDCl 3 ) δ (ppm): 8.44 (s, 2H), 7.85–7.71 (m, 8H), 7.60–7.57 (m, 2H) (aryl rings), 4.49 (br s, 2H, carbazole–N–CH 2 –), 2.83–2.71 (m, 1H), 2.37–2.29 (m, 14H), 1.68 (m, 2H), 1.33 (m, 2H), 0.93–0.61 (m, 36H) (alkyl chain). Element Anal. Found: C, 84.92%; H, 8.72%; N, 3.36%; S, 1.57%. PFCzN–DHTBT10: 1 H NMR (300 MHz, CDCl 3 ) δ (ppm): 8.44 (s, 2H), 7.85–7.72 (m, 8H), 7.60–7.57 (m, 2H) (aryl rings), 4.49 (br s, 2H, carbazole–N–CH 2 –), 2.82–2.72 (m, 1H), 2.37–2.16 (m, 16H), 1.74 (m, 2H), 1.34 (m, 4H), 0.93–0.59 (m, 44H) (alkyl chain). Element Anal. Found: C, 83.02%; H, 9.15%; N, 3.86%; S, 2.59%. PFCzN–DHTBT15: 1 H NMR (300 MHz, CDCl 3 ) δ (ppm): 8.44 (s, 2H), 7.87–7.72 (m, 9H), 7.60–7.49 (m, 4H) (aryl rings), 4.49 (br s, 2H, carbazole–N–CH 2 –), 2.83–2.71 (m, 1H), 2.37–2.13 (m, 15H), 1.74 (m, 2H), 1.38–1.26 (m, 5H), 0.93–0.55 (m, 46H) (alkyl chain). Element Anal. Found: C, 83.42%; H, 8.86%; N, 3.78%; S, 3.52%. 3.1 LED fabrication and characterization The PLEDs were fabricated on ITO-covered glass substrates. Patterned indium tin oxide (ITO)-coated glass substrates were cleaned with acetone, detergent, distilled water, and isopropyl alcohol, subsequently in an ultrasonic bath. After treatment with oxygen plasma, 150 nm of poly(3,4-ethylenedioxythiophene) (PEDOT) doped with poly(styrenesulfonic acid) (PSS) (Batron-P 4083, Bayer AG) was spin-coated onto the ITO substrate followed by drying in a vacuum oven at 80 °C for 8 h. For some devices, poly(vinylcarbazole) (PVK, Aldrich) from 1,1,2,2-tetrachloroethane solution was coated on top of a dried PEDOT–PSS layer subsequently. The polymers were dissolved in toluene and filtered through a 0.45 μm filter. A thin film of polymer was coated onto the anode by spin-casting inside a dry box. The film thickness of the active layers was around 70 nm, as measured with an Alfa Step 500 surface profiler (Tencor). A thin layer of Ba (4–5 nm) and subsequently Al (200 nm) were vacuum-evaporated subsequently on the top of the EL polymer layer under a vacuum of 1 × 10 −4 Pa. Device performances were measured inside a drybox. Current–voltage ( I – V ) characteristics were recorded by a Keithley 236 source meter. EL spectra were recorded by Oriel Instaspec IV CCD spectrograph. Luminance was measured by a PR 705 photometer (Photo Research). The external quantum efficiencies were determined by a Si photodiode with calibration in an integrating sphere (IS080, Labsphere). To avoid contamination of volatile low-work-function metal (Ba) during Al cathode deposition on top of the PFCzN–DHTBT layer, an evaporation chamber was thoroughly cleaned through baking at 120–130 °C and at a high vacuum (<1 × 10 −4 Pa) before Al deposition. The control devices [ITO/PEDOT/MEH–PPV/(or Ba)Al] were fabricated. The extra quantum efficiencies of the devices 1.94% and 0.014%, respectively, with the configuration: ITO/PEDOT/MEH–PPV/(or Ba)/Al ensured that high-work-function metal Al was not contaminated by low-work-function Ba in the evaporation chamber from the previous deposition. 4 Results and discussion 4.1 Synthesis and characterization Copolymers were synthesized from co-monomers 1 , 2 and 3 by Suzuki polycondensation (shown in Scheme 1 ). The feed ratios of DHTBT monomer are 0.1, 1, 5, 10, 15 mol%, and the corresponding copolymers are named, respectively, as PFCzN–DHTBT01, PFCzN–DHTBT1, PFCzN–DHTBT5, PFCzN–DHTBT10 and PFCzN–DHTBT15. The monomer feed molar ratios were adjusted in order to investigate the effect of composition on the physical and optical properties of copolymers. The actual composition of PFCzN–DHTBT copolymer calculated from the sulfur, nitrogen and carbon results of elemental analyses is close to the feed ratios of monomers as listed in Table 1 . All the copolymers have good solubility in common solvents such as chloroform, toluene, and THF, since 2-ethylhexyl substituents in the 9-position of fluorene and n -hexyl substituents in the 4-position of thiophene and 9-dimethylaminopropyl group in the N-position of carbazole were employed to improve the solubility of the resulted copolymers. The number-average molecule weights ( M n ) of the synthesized copolymers are in the range of 6000–10000 g/mol with polydispersity index (PDI) of around 1.3–1.6, typical for a polycondensation reaction. The thermal properties of polymers were evaluated by TGA and DSC. TGA reveals excellent thermal stabilities of copolymers as shown in Fig. 1 . The thermal decomposition temperatures (5% weight loss) of PFCzN–DHTBT01, PFCzN–DHTBT1, PFCzN–DHTBT5, PFCzN–DHTBT10 and PFCzN–DHTBT15 are 395, 400, 403, 412 and 404 °C, respectively ( Table 1 ). The residual weights of copolymers are all greater than 50% when the temperature rise to 800 °C. The high residual yields of the copolymers could be explained by the intramolecular carbonization during the heating process due to their torsion structure in the backbone, which makes two nearby main chains carbonize easily with each other [32] . All the copolymers showed same one-step decomposition process and the initial weight loss started at about 350 °C, which could be ascribed to side chain decomposition upon heating process. The glass-transition temperature ( T g ) of PFCzN–DHTBT01, PFCzN–DHTBT1, PFCzN–DHTBT5, PFCzN–DHTBT10 and PFCzN–DHTBT15 were 145, 141, 100, 97 and 86 °C ( Table 1 ), as determined by differential scanning calorimetry (DSC). With the content of DHTBT unit increasing, the T g s of the copolymers decrease. This owes to the weaker intermolecular interactions and the increasing intrachain irregularity caused by introducing more DHTBT units to copolymer main chain [33] . 4.2 UV–vis absorption and electrochemical properties The absorption spectra of the copolymers in CHCl 3 solution and in film are shown in Fig. 2 . All the polymers show similar absorption spectra in solution ( Fig. 1 a) and in film ( Fig. 1 b). The spectra of copolymers are dominated by two absorption bands peaked at around 345 nm ( Table 2 ), which can be attributed to the FCzN segments [32] in the copolymers, and peaked at around 510 nm, which can be attributed to the DHTBT unit incorporated into the polymer main chain [30] . The low-energy absorption intensities increase with the increasing content of DHTBT unit in the copolymers. The electrochemical properties of the copolymers were investigated by cyclic voltammetry (CV) in order to gauge their electronic properties. All the electrochemical data of the copolymers obtained from the films are listed in Table 2 . The copolymers show one p-doping wave but failed to detect n-doping process. The copolymers show only one quasi-reversible oxidation wave with the onsets around 0.83–0.87 eV. The oxidation waves can be assigned to the oxidation process for the PFCzN segment [32] . The highest occupied molecular orbital (HOMO) levels are calculated according to the following empirical formulas: E HOMO = − e ( E ox + 4.40) (eV) [34] , and the lowest unoccupied molecular orbital (LUMO) levels are estimated from the optical band gap that are calculated from the absorption onset of copolymers in thin film ( Table 2 ). HOMO and LUMO levels of copolymers, respectively, decrease from −5.23 and −2.13 eV to −5.27 and −3.19 eV with the increase of DHTBT content, indicating a much lower barrier for hole and electron injection from PEDOT–PSS (5.2 eV) [35] , and Ba (2.8 eV) or Al (4.2 eV) [36] , respectively. 4.3 Photoluminescence properties Fig. 3 shows the PL spectra of the copolymers in CHCl 3 solution and in the thin film, respectively. In CHCl 3 solution ( Fig. 3 a), with the copolymer concentration of 1 × 10 −5 mol/L (by repeat unit), except copolymer PFCzN–BHTBT01, all the copolymers show two emission peaks at around 405 and 630 nm. The emission intensities peaked at 405 nm decrease while the intensities peaked at 630 nm increase with increasing the DHTBT content in the copolymers. Therefore, 405 and 630 nm emissions can be assigned to FCzN segment and DHTBT unit in the copolymers, respectively. In the thin film, the emission of FCzN segment is completely quenched except the copolymer PFCzN–BHTBT01, and PL emission is dominated by the red emission at around 630 nm with the DHTBT content even as low as 1 mol% ( Fig. 3 b). PL emission peaks are gradually red-shifted with the increasing DHTBT content in the copolymers, from 595 nm for PFCzN–BHTBT01 to 636 nm for PFCzN–BHTBT15. The PL efficiencies (QE P L ) of the copolymers are listed in Table 2 . All the polymers possess high PL efficiencies due to the effective intra- and intermolecular energy transfer in these copolymers. It is shown that the PL efficiencies increase when small amount of DHTBT unit are introduced into polymer backbone. The PL efficiencies of PFCzN–DHTBT01 and PFCzN–DHTBT1 are enhanced up to 49% and 67%, respectively, compared with 19% for PF- alt -CzN copolymer [32] . Further increasing DHTBT content to 15 mol%, the PL efficiencies of copolymers are slightly decreased from 41% for PFCzN–DHTBT5 to 36% for PFCzN–DHTBT15. It is due to the fact that the strong inter-chain interaction between aminoalkyl-substituted cabarzole unit is disturbed severely by the small amount of DHTBT unit introduced into polymer backbone, which suppress both radiative decay from FCzN segment and excimer emission in PFCzN inter-chain aggregates. 4.4 Electroluminescent properties Owing to the low electron affinity and low drifting mobility of electron in EL polymers, the electron injection between the emitting layer and the metal cathode should be improved to obtain a more balanced charge carriers in the device. Low work functional metals, such as Ba (work function φ = 2.8 eV) and Ca ( φ = 2.9 eV), are typically used as cathodes to facilitate the electron injection. Since low work functional metals are susceptible to degradation upon exposure to water and oxygen, more stable electron injection cathodes made of high work functional metals are desirable. The PFCzN–DHTBT copolymer can function as both light-emitting and electron injection layers simultaneously. The EL spectra of these copolymers are presented in Fig. 4 . It is shown that only a red emission is observed even though the DHTBT content is as low as 0.1 mol%. This fact indicates that energy transfer in EL process from FCzN segment to DHTBT unit is efficient and complete, as like the case of PL emission. The quenched host emission at DHTBT content as low as 1 mol% for both PL and EL processes implies that the energy transfer of PFCzN–DHTBT copolymers occurs mainly via trapping mechanism. The generated exciton is efficiently confined on the DHTBT site, so that polymers emit exclusively the narrow-band-gap component DHTBT. EL peaks are generally 20 nm red-shifted ( Tables 2 and 3 ) in comparison with the PL emission of corresponding copolymers. The red-shifted EL emission with the increasing DHTBT content, as observed in PL spectra, from 614 nm for PFCzN–DHTBT01 to 658 nm for PFCzN–DHTBT15, indicates an aggregation among DHTBT units of neighboring chains. The EL performances of polymers were examined in the device configuration of ITO/PEDOT (or PVK)/polymer/(or Ba)/Al. The detailed device performances are listed in Tables 3 and 4 . It is shown that all polymers show similar external quantum efficiencies, regardless of whether a low functional metal Ba or a high functional metal Al was used as the cathode. The maximum external quantum efficiencies (EQE max )s of devices with Al as cathode and PVK as anode buffer layer for PFCzN–DHTBT01, PFCzN–DHTBT1, PFCzN–DHTBT5, PFCzN–DHTBT10 and PFCzN–DHTBT15 are 0.18%, 0.23%, 0.75%, 0.84% and 0.77%, respectively ( Table 4 ). The (EQE max )s for PFCzN–DHTBT10 are 1.10% and 0.84% at the luminance of 624 and 507 cd/m 2 , respectively, with device configuration: ITO/PEDOT/PVK/polymer/(or Ba)/Al. The comparable device efficiencies achieved by Al and Ba cathodes for copolymers in this paper indicate that the barrier height on the interface between the active layer and Al cathode is significantly reduced to allow efficient electron injection [36] . Tables 3 and 4 compare the device performances of polymers using PEDOT–PSS or PVK as anode buffer. It can be found that the device efficiencies are significantly enhanced for all copolymers except PFCzN–DHTBT01 and PFCzN–DHTBT1 when PVK was used as anode buffer. Since HOMO and LUMO levels for the copolymer are around −5.2 and −3.1 eV ( Table 2 ), while the work functions of PEDOT and Ba are around 5.0–5.2 eV and 2.8 eV, respectively, obviously there exists no injection barrier for electron, while there is a barrier of 0.2 eV for hole to overcome. The current densities ( J ) and luminances ( L ) of the devices versus voltage ( V ) of the device of PFCzN–DHTBT10 copolymer with different configurations are shown in Fig. 5 . It is noticeable that the devices with Al cathode show almost the same operating voltage as the devices with Ba/Al cathode. Moreover, as shown in Fig. 5 , the decreased current densities of the devices with PVK buffer layer compared with PEDOT devices indicate that the electron leakage current is depressed leading to an enhanced efficiency. Therefore, it suggests that PVK (HOMO: −5.4 eV, LUMO: −1.9 eV) [37] plays a role of electron-blocking and leads to more balanced charge carriers in the device. 5 Conclusions Amino-containing saturated red light-emitting copolymers PFCzN–DHTBT were synthesized via Suzuki polycondensation. The dimethylaminopropyl group in the polymer side chain can lower the barrier height on the interface between metal cathode and light-emitting polymer. As a result, high work functional metal Al can be used as cathode in PLEDs with similar device performances to those with lower work functional metal Ba cathode. The (EQE max )s of the copolymer PFCzN–DHTBT10 achieved 0.84% (or 1.1%) with the device configuration: ITO/PEDOT/PVK/polymer/Al (or Ba/Al) with an emission peaked at 650 nm. Acknowledgement The authors are grateful to the Ministry of Science and Technology (No. 2002CB 613402), and the National Natural Science Foundation of China (No. 20574021, U0634003, 50433030) for their financial support. 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        "keywords": [
            "al cathode",
            "amino-containing carbazole",
            "copolymers",
            "fluorene",
            "red emission",
            "glass transition temperature",
            "thermal stability"
        ],
        "authors": [
            {
                "name": "Rong Guan",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Lab of Specially Functional Materials, Ministry of Education, South China University of Technology, Guangzhou 510640, China"
            },
            {
                "name": "Chun Li",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Lab of Specially Functional Materials, Ministry of Education, South China University of Technology, Guangzhou 510640, China"
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Wenbin Sun",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Lab of Specially Functional Materials, Ministry of Education, South China University of Technology, Guangzhou 510640, China"
            },
            {
                "name": "Hongbin Wu",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Lab of Specially Functional Materials, Ministry of Education, South China University of Technology, Guangzhou 510640, China"
            },
            {
                "name": "Lei Ying",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Lab of Specially Functional Materials, Ministry of Education, South China University of Technology, Guangzhou 510640, China"
            },
            {
                "name": "Yong Cao",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Lab of Specially Functional Materials, Ministry of Education, South China University of Technology, Guangzhou 510640, China"
            }
        ],
        "venue": "Dyes and Pigments",
        "year": 2008
    },
    "n741dhkO": {
        "id": "n741dhkO",
        "title": "White emission polymer light-emitting devices with efficient electron injection from alcohol/water-soluble polymer/Al bilayer cathode",
        "abstract": "We demonstrate highly efficient white emission polymer light-emitting diodes (WPLEDs) from multilayer structure formed by solution processed technique, in which alcohol/water-soluble polymer, poly [(9,9-bis(3′-( N , N -dimethylamino)propyl)-2,7-fluorene)-alt-2,7-(9,9-dioctylfluorene)] (PFN) was incorporated as electron-injection layer and Al as cathode. It was found that the device performance was very sensitive to the solvents from solution of which the PFN electron-injection layer was cast. Devices with electron-injection layer cast from methanol solution show degraded performance while the best device performance was obtained when mixed solvent of water and methanol with ratio of 1:3 was used. We attribute the variation in device performance to washing out the electron transport material in the emissive layer due to rinse effect. As a result of alleviative loss of electron transport material in the emissive layer, the optimized device with a peak luminous efficiency of 18.5 cd A −1 for forward-viewing was achieved, which is comparable to that of the device with same emissive layer but with low work-function metal Ba cathode (16.6 cd A −1 ). White emission color with Commission International de I’Eclairage coordinates of (0.321, 0.345) at current 10 mA cm −2 was observed. Keywords White emission polymer light-emitting devices Electron-injection layer Alcohol/water-soluble polymer 1 Introduction White organic light-emitting devices (WOLEDs) are of intense interest because of their potential applications in full-color flat-panel displays, solid-state lighting source and backlights for liquid-crystal displays [1–3] . Various approaches towards realizing WOLEDs have been reported, which include doping of RGB fluorophors or phosphors in a small molecule or polymer host [4–8] , synthesis of a single polymer incorporating RGB emitting moieties in the polymer backbone or side chain [9,10] , use of excimer or exciplex formed by one or two dopants [11–13] , multilayer device with consecutive evaporations of RGB-emitting compounds [14,15] . So far, efficiency of WOLEDs based on vacuum deposited technology have exceeded that of the incandescent light bulb (12–17 lm W −1 ) [1] . In contrast, only a few demonstrations with high efficiency exceeding this benchmark were reported for WPLEDs [16,17] , and for most of white emission PLEDs, their power efficiencies are still much lower tan 10 lm W −1 mainly due to unbalanced charge injection, unsatisfactory charge transport and weak confinement of electron and hole [15] . Therefore, one of the most critical factors in achieving high efficiency for a given polymer is to obtain balanced electron and hole injection and effective confinement over the charge carrier. To minimize the injection barrier height for electron, low work-function metals are usually employed as cathode [18,19] . However, since the low-work function metals are susceptible to degradation upon water vapor and oxygen, high work-function metal, thereby more stable electron injection cathodes are desirable, if they can provide comparable device efficiency. Over the past years, significant efforts have been made to develop a new electron injection cathode from high work-function metals in order to reach a high environmental stability, easy fabrication in combination with high device efficiency and a low operating voltage. For example, Park et al. reported the use of the ionomer-type and salt-type electron-injection layer with air-stable metal Al as cathode [20,21] . Recently, several groups reported that thin film of alcohol- or water-soluble conjugated polymer in combination with air-stable metals (such as Al, Ag, and Au) can be used as efficient electron injection cathode for PLEDs with high efficiency of green or red-emitting devices [22–29] . And more recently, Zhang et al. have developed a novel method in which a thin layer of poly[9,9-bis(6′-(diethanolamino)hexyl)-fluorene] (PFN-OH) spin-coated from water/ethanol mixed solvent was used as electron-injection layer for WPLEDs consisting of two phosphores (blue Ir complex and orange Os complex) doped into poly( N -vinylcarbazole) (PVK), the device efficiency is much higher than that with PFN-OH cast from neat ethanol, to improve the performance of white phosphorescent PLEDs by manipulating the morphology of the electron-injection layer through solvent processing [17] . In this letter, we demonstrate that analogous concepts can be applied to fabricate highly efficient multilayer WPLEDs based on blue and red Ir complexes, FIrpic and Ir(piq), respectively, in which a water/alcohol-soluble polymer, poly[(9,9-bis(3′-( N , N -dimethylamino)propyl)-2,7-fluorene)-alt-2,7-(9,9-dioctylfluorene)] (PFN) [24] was used as electron-injection layer, and air-stable, high work-function metal Al was used as cathode. We also found out that the device performance was very sensitive to the solvent composition from which PFN layer was cast, which is consistent with previous report [17] . We proposed that washing out of electron transport materials, 1,3-bis[(4-tert-butylphenyl)-1,3,4-oxadiazolyl] phenylene (OXD-7) component in the EML layer upon spin-coating of PFN layer from methanol solution is an important reason responsible for degradation of such device performance. Addition of water into PFN methanol solution prevents erosion of Ir complexes/PVK layer undernearth and makes efficient electron injection from bilayer cathode possible. This implies that multilayer configuration is an effective approach for producing low-cost, and large-area size white PLEDs by spin-coating. 2 Experimental details Devices configurations used in this study is ITO/poly (ethylendioxythiophene):poly (styrene sulfonic acid) (PEDOT:PSS) (40 nm)/PVK:OXD-7:FIrpic (5%):Ir(piq) (0.25%)(70–80 nm)/cathode, in which PVK (70 wt%)/OXD-7 (30 wt%) form the host matrix, iridium bis(2-(4,6-difluorophenyl)-pyridinato- N,C 2 ′) picolinate (FIrpic, blue emission) and iridium bis(1-phenylisoquinoline) (acetylacetonate) (Ir(piq), red emission) are efficient triplet emitters. PVK was purchased from Aldrich, Ir(piq) were obtained from America Dyes Sources, respectively, and used as received. FIrpic, OXD-7 and PFN were synthesized in our laboratory. The chemical structure of PFN is shown in Scheme 1 . PEDOT:PSS (Baytron P 4083, Bayer AG) was purchased from H. C. Starck, Inc. The fabrication of devices followed well-established processes [25] . Patterned indium tin oxide (ITO) coated glass with a sheet resistance of 15–20 Ω/square were cleaned by a surfactant scrub, then underwent a wet-cleaning process inside an ultrasonic bath, beginning with deionized water, followed by acetone and isopropanol. After oxygen plasma cleaning for 4 min, a 40 nm-thick PEDOT:PSS anode buffer layer of was spin-cast on the ITO substrate and then dried by baking in vacuum oven at 80 °C overnight. The emitting layer, with thickness in the 70–80 nm range, was then deposited on top of PEDOT layer, by casting from a chlorobenzene solution containing PVK (60 wt%):OXD-7 (30 wt%):FIrpic (10 wt%):Ir(piq) (0.5 wt%), followed by thermal annealing at 120 °C for 30 min. A Tencor, Alfa-Step 500 surface profiler was used to determine thickness of the PEDOT and EL polymer films. Deposition of PFN layers and determination of their thickness follows a previously published paper [24,25] and thickness control is adjusted by spin speed between 600 rpm to 2500 rpm. In a word, the thickness of PFN was determined by a surface profiler (Alfa Step-500, Tencor) in combination with extrapolation from an absorbance–thickness curve assuming a linear dependence of absorbance at 380 nm of PFN peak on the film thickness. Prior to making the co-solvent solution, the solubility of PFN in methanol and water was checked, respectively. It was found when dissolved into methanol, with a few drops of acetic acid added and heating up to 60 °C, a concentration of 10–15 mg/ml was reached, yielding a clear solution with no sign of saturation. Nevertheless, the solubility decreases rapidly in water, for instance, even dissolving 2 mg of PFN in 1 mL of water requires heating, apparently due to the reduced solvent polarity. Given these conditions, when we handled with water/methanol (6v/1v) co-solvent solution, or any other co-solvent solution, we made PFN methanol solution first, for example, in a concentration of 2–5 mg/ml. Depending on the water/methanol blending ratio, corresponding amount of water is added to form the targeted diluted solution. When water was added in the prepared PFN methanol solution, the resulted mixed solution became slightly ropy whereas remained clear. Finally, 4 nm barium and 100 nm aluminum layer were evaporated with a shadow mask at a base pressure of 3 × 10 −4 Pa. The thickness of the evaporated cathodes was monitored by a quartz crystal thickness/ratio monitor (Model: STM-100/MF, Sycon). The structure of electron-only devices we studied in this letter is ITO/Ba(20 nm)/EML(70-80 nm)/PFN(20 nm)/Al(120 nm). 20 nm barium layer were evaporated on the ITO substrate with a shadow mask at a base pressure of 3 × 10 −4 Pa. The overlapping area between the cathode and anode defined a pixel size of 17 mm 2 . Except for the deposition of the PEDOT layers, all the fabrication processes were carried out inside a controlled atmosphere of nitrogen dry-box (Vacuum Atmosphere Co.) containing less than 10 ppm oxygen and moisture. The current–luminance–voltage ( I – L – V ) characteristic was measured using a Keithley 236 source-measurement unit and a calibrated silicon photodiode. The forward-viewing luminance was calibrated by a spectrophotometer (SpectraScan PR-705, Photo Research) and the forward-viewing LE was calculated accordingly. Throughout the whole manuscript, reported value of luminance and LE are for forward-viewing direction only. The external quantum efficiency of EL was collected by measuring the total light output in all directions in an integrating sphere (IS-080, Labsphere). The photoluminescent spectra was recorded by a single-grating monochromator (Instaspec IV, Oriel Co.) equipped with a CCD detector, and electroluminescent spectra was collected by a PR-705 photometer. The photovoltaic measurement was carried out under white-light illumination using a xenon lamp (150 W, Oriel) as a light source. 3 Results and discussion Fig. 1 a display the forward-viewing luminous efficiency–current density (LE– J ) characteristics of the devices with different cathodes (Al, Ba/Al, PFN (methanol)/Al, PFN (water/methanol, 1v/3v)/Al, respectively). All the thickness of PFN was fixed at its optimized value of 20 nm. It was found that that the maximal LE of the device with neat Al as cathode is only 0.59 cd A −1 , which is consistent with the fact that Al has a work-function of 4.3 eV and a big electron injection barrier exists at the PVK/Al interface. On the other hand, it is interesting to note that changing the solution composition for PFN coating can make a substantial impact on the device performance. The maximal LE of the device with PFN (water/methanol, 1v/3v)/Al as cathode can be as high as 18.5 cd A −1 , while a maximal luminance of 8672 cd m −2 was obtained at 12.6 V ( Fig. 1 b). This is comparable to that of device with low work-function metal Ba as cathode (a peak forward-viewing LE of 16.6 cd A −1 and a maximal luminance of 7823 cd m −2 at 13.2 V, respectively). We also note that insertion of additional Ba between PFN (water/methanol, 1v/3v) layer and Al have minor effect on the device performance further indicating that the enhancement is originated from the incorporation of PFN layer itself. On the other hand, the maximal LE of device with the PFN (methanol)/Al device is only 1.0 cd A −1 with a maximal luminance of 351 cd m −2 at 10.6 V. We also note that the turn-on voltage (defined as voltage at which luminance of 1 cd m −2 was detected) of the device with the PFN (methanol)/Al is quite high (6.3 V), while for the device with PFN (water/methanol, 1v/3v)/Al, lower turn-on voltage of 4.8 V was observed, close to that of Ba/Al device (3.9 V). J – L – V characteristics of the devices with the four types of cathodes are presented in Fig. 1 b. It is obvious that the PFN (water/methanol, 1v/3v)/Al bilayer cathode provides an efficient electron injection due to reduced electron injection barrier height [25,26] and the device performance with such bilayer cathode was dramatically enhanced over plain Al cathode devices. On the other hand, despite its poor device performance, the PFN(methanol)/Al device exhibit the maximal current density over any other devices at any voltage studied, suggesting that its device performance is limited by imbalanced charge carriers transport rather than by injection of electron itself. This is supported by built-in potential measurement [23,25] shown in Fig. 2 . As deduced from the J – V cure under illumination from solar simulator, the built-in across the device shift from 1.30 V for a plain Al device to about 1.60–1.70 V for the PFN(W/M)/Al, PFN(M)/Al and Ba/Al cathode device. This reveals that the built-in potentials of all of the three types of devices are very close (with difference of only 0.05 V), indicating electron injection barrier height of these devices are similar. In order to further clarify the influence of solvent composition on the charge transport properties of the device, it is necessary to compare the sole current of electron. Therefore, hole carrier flux must be suppressed by a large barrier to form an electron-only device. Since highest occupied molecular orbital (HOMO) of PVK is −5.8 eV, an hole injection barrier of 3.0 eV is expected when using low work-function metal such as Ba (2.8 eV) as anode. Two sets of electron-only devices in configuration like ITO/Ba(20 nm)/EML(70–80 nm)/PFN(20 nm)/Al(120 nm) were fabricated with PFN layers processed from two types of solvents, respectively, and their J – V characteristics is shown in Fig. 3 . In order to obtain reliable anode/polymer contact with extra high injection barrier height, prior to spin-coating of EML, 20 nm of barium film was evaporated on precleaned ITO substrate with a shadow mask at a base pressure of 3 × 10 −4 Pa. More importantly, anhydrous grade chlorobenzene (Aldrich) containing negligible water (less than 0.005 wt%) was used as solvent for the EML solution to alleviate erosion. Negligible emission from the resulted devices further confirmed that electron is the dominant charge carrier in the devices. In addition, diodes characteristics shown in Fig. 3 also confirmed that it is not likely the 20 nm of barium be oxidated by the residue water completely. It is found that electron current density through PFN (water/methanol, 1v/3v)/Al device is significantly higher than that of PFN(methanol)/Al device, which must be results of the better electron transport properties in the former device keeping in mind that the electron injection barriers are the same for these two type of devices. In addition, the fact that insufficient electron transport in the PFN(methanol)/Al device results in higher total current density through the device can be understood if one take into account the fact that electron accumulation at the internal interface can gives rise to a significant redistribution of the electric field inside the device [30] . Furthermore, imbalanced charge transport in the bulk of PFN (methanol)/Al was also supported by the EL spectra of the PFN (methanol)/Al device ( Fig. 4 ), which will be discussed later. It is also worthy to point out that changing the ratio between water and methanol can significantly affect on the device performance of the WPLEDs. Table 1 presents the influence of various solvent ratios (from 6:1 to 1:10 by volume, water to methanol) on peak LE, peak luminance and CIE coordinates (at 10 mA cm −2 ) the devices. It can be seen that the best device performance (highest LE) is obtained when water/methanol ratio is 1v/3v. Fig. 4 displayed the EL spectra of the white PLEDs with different cathodes (Al, Ba/Al, PFN(methanol)/Al, PFN(water/methanol, 1v/3v)/Al) at a current density of 10 mA cm −2 ,which corresponded to CIE coordinates of (0.366,0.362), (0.320,0.369), (0.205,0.328), and (0.321,0.345), respectively, very close to ideal white emission point (0.33, 0.33). For all of the EL spectra, two intense peaks around 470 nm and 620 nm and a small shoulder peak at 500 nm were clearly observed, which can be assigned to the emission from FIrpic and Ir(piq). However, the device with PFN (methanol)/Al as cathode shows additional emission peak at 420 nm, which can be attributed to the EL emission of PFN layer itself, indicating that the exciton recombination zone shift towards cathode side as a result of imbalanced charge carrier transport in such device and accumulated electron at PFN/emissive layer interface. In contrast, PLEDs with single emissive component (i.e. phenylenevinylene or polyfluorene derivative) does not show such dependence on the solvent from which PFN layer was spin-cast. As clearly seen from Fig. 5 , with green emitting poly[2-(4-(3′,7′-dimethyloctyloxy)-phenyl)- p -phenylenevinylene] (P-PPV) as emissive layer, both PFN(M)/Al and PFN(W/M)/Al cathode device show significant enhancement with a peak luminous efficiency around 16 cd A −1 when compared with the plain Al device (∼0.40 cd A −1 ). We speculate that in the white emission device with PFN (methanol)/Al device, methanol dramatically affect on electron transport in the device by washing away OXD-7, resulting in imbalanced electron transport, therefore leading to degraded device performance. Since FIrpic had been shown to exhibit bipolar transport properties [31] , the reduced electron transport properties in the device had even greater impact on the excitation of Ir(piq), leading to a significantly reduced red emission from Ir(piq). Furthermore, since charge trapping is the dominant process in the electrical excitation of these devices [8] , and Ir(piq) serve as hole traps due to its high HOMO level, it is expected that a reduced electron transport will significantly influence the excitation of the Ir(piq), fully consistent with the observation shown in Fig. 4 . The emission color of the device with PFN (water/ethanol, 1v/3v)/Al as cathode showed minor color shift upon change of applied current density, for example, as the current density increase from 5 mA cm −2 to 10, 20, and 50 mA cm −2 , CIE coordinates shifted from (0.325,0.345) to (0.321,0.347). EL spectra for device with PFN (water/methanol, 1v/3v)/Al at different current density are also shown in the inset of Fig. 4 . In order to get insight into the strong dependence of device performance on the solvent composition, UV–Vis spectra of neat EML and equivalent film treated by methanol and mixed solvent (water/methanol, 1v/3v) were compared (inset in Fig. 6 ). As shown in Fig. 6 , it was found that the spectral difference between the neat film and those treated by methanol is consist with the UV–Vis spectra of OXD-7, while in contrast, UV–Vis spectra of the neat film and the film treated with mixed solvent (water/methanol, 1v/3v) was nearly identical, thus confirm removal of the small molecule in the EML in somehow upon drop casting of PFN from methanol solution atop. The mechanisms of alleviative erosion of PVK:OXD-7:Ir complexes upon incorporation of water into PFN methanol solution is not clear so far and will be investigated in the follow-up study. 4 Conclusions In summary, highly efficient white emission polymer light-emitting diodes was fabricated from multilayer structure formed by solution processed technique using a water/alcohol-soluble polymer as electron-injection layer, and air-stable, high work-function metal Al was used as cathode. To obtain optimized device performance, 25% amount of water was added into PFN methanol solution to prevent erosion of Ir complexes/PVK layer undernearth and makes efficient electron injection from bilayer cathode and transport possible. The maximal luminance efficiency of the resulting device increase immensely from 0.59 cd A −1 for device with neat Al cathode, 1.0 cd A −1 for device with PFN spin-coated from methanol to 18.5 cd A −1 for devices with optimized PFN/Al cathode, which is comparable to those obtained using Ba cathode. We found that washing out of electron transport materials, OXD-7 component in the EML layer upon spin-coating of PFN layer from methanol solution is an important reason responsible for degradation of such device performance. Addition of water into PFN methanol solution prevents erosion of Ir complexes/PVK layer undernearth although the mechanism is not clear so far. Using air-stable metals as cathode makes these white emitting PLEDs promising candidates for lighting applications. Our study implies that multilayer configuration is an effective approach for producing low-cost, and large-area size white PLEDs by spin-coating. Acknowledgements The authors are grateful to the Natural Science Foundation of China (Project Nos. 50433030 and U0634003) and the Ministry of Science and Technology Project (No. 2002CB613400) for the financial support. References [1] B.W. D’Andrade S.R. Forrest Adv. Mater. 16 2004 1585 [2] A. Misra P. Kumar M.N. Kamalasanan S. Chandra Semicond. Sci. Technol. 21 2006 R35 [3] R. Duggal J.J. Shiang C.M. Heller D.F. Foust Appl. Phys. Lett. 80 2002 3470 [4] P.I. Shih Y.H. Tseng F.I. Wu A.K. Dixit C.F. Shu Adv. Funct. Mater. 16 2006 1582 [5] S. Kim J. Seo H.K. Jung J.-J. Kim S.Y. Park Adv. Mater. 17 2005 2077 [6] X. Gong W.L. Ma J.C. Ostrowski G.C. Bazan D. Moses A.J. Heeger Adv. Mater. 16 2004 615 [7] Y. Shao Y. Yang Appl. Phys. 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J. Appl. Phys. 44 2005 3691",
        "keywords": [
            "alcohol/water-soluble polymer",
            "electron-injection layer",
            "white emission polymer light-emitting devices",
            "electron transport",
            "water soluble",
            "work function",
            "light emitting diode"
        ],
        "authors": [
            {
                "name": "Ding An",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Laboratory of Specially Functional Materials of the Ministry of Education, South China University of Technology, 381 Wushan Road, Guangzhou 510640, PR China"
            },
            {
                "name": "Jianhua Zou",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Laboratory of Specially Functional Materials of the Ministry of Education, South China University of Technology, 381 Wushan Road, Guangzhou 510640, PR China"
            },
            {
                "name": "Hongbin Wu",
                "org": ""
            },
            {
                "name": "Junbiao Peng",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Laboratory of Specially Functional Materials of the Ministry of Education, South China University of Technology, 381 Wushan Road, Guangzhou 510640, PR China"
            },
            {
                "name": "Wei Yang",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Laboratory of Specially Functional Materials of the Ministry of Education, South China University of Technology, 381 Wushan Road, Guangzhou 510640, PR China"
            },
            {
                "name": "Yong Cao",
                "org": ""
            }
        ],
        "venue": "Organic Electronics",
        "year": 2009
    },
    "ta0WaMzl": {
        "id": "ta0WaMzl",
        "title": "Analysis of soft impingement in nonisothermal precipitation",
        "abstract": "",
        "keywords": [
            "annealing"
        ],
        "authors": [
            {
                "name": "Kai Fan",
                "org": ""
            },
            {
                "name": "Feng Liu",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Gencang Yang",
                "org": ""
            },
            {
                "name": "Yaohe Zhou",
                "org": ""
            }
        ],
        "venue": "Journal of Materials Research",
        "year": 2009
    },
    "LVSeYBaQ": {
        "id": "LVSeYBaQ",
        "title": "A new approach to efficiency enhancement of polymer light-emitting diodes by deposition of anode buffer layers in the presence of additives",
        "abstract": "Here we report a new approach for the preparation of anode buffer layer for efficient polymer light-emitting devices (PLEDs) by using glycerol to modify relative low conductivity poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS). This new type of anode buffer layer allows for a 50–90% increase in device performance for green emitting phosphorescent PLEDs in terms of luminous efficiency, and external quantum efficiency, while 90–150% in power efficiency, as compared to devices fabricated using commercially available PEDOT:PSS. The green emitting phosphorescent PLEDs with this modified anode buffer exhibit very high efficiencies, representing a significant step forward to matching and exceeding the efficiencies reported to date with vacuum-deposited small molecular devices. We anticipate that these findings can provide a simple experimental procedure for improvement of PLEDs.",
        "keywords": [
            "polymer light-emitting devices (pleds)",
            "poly(3",
            "conductivity",
            "78.60.fi",
            "anode buffer layer",
            "72.80.le",
            "4-ethylenedioxythiophene):poly(styrene sulfonate) (pedot:pss)",
            "high-efficiency",
            "85.60.jb",
            "external quantum efficiency",
            "light emitting diode",
            "power efficiency"
        ],
        "authors": [
            {
                "name": "Hongbin Wu",
                "org": ""
            },
            {
                "name": "Jianhua Zou",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Lab Specially Functional Materials and Advanced Manufacturing Technology, South China University of Technology, Guangzhou 510640, People’s Republic of China"
            },
            {
                "name": "Ding An",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Lab Specially Functional Materials and Advanced Manufacturing Technology, South China University of Technology, Guangzhou 510640, People’s Republic of China"
            },
            {
                "name": "Feng Liu",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Lab Specially Functional Materials and Advanced Manufacturing Technology, South China University of Technology, Guangzhou 510640, People’s Republic of China"
            },
            {
                "name": "Wei Yang",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Lab Specially Functional Materials and Advanced Manufacturing Technology, South China University of Technology, Guangzhou 510640, People’s Republic of China"
            },
            {
                "name": "Junbiao Peng",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Lab Specially Functional Materials and Advanced Manufacturing Technology, South China University of Technology, Guangzhou 510640, People’s Republic of China"
            },
            {
                "name": "Alexander Mikhailovsky",
                "org": "Department of Biochemistry and Materials, Institute for Polymers and Organic Solids, University of California, Santa Barbara, CA 93106, USA"
            },
            {
                "name": "Guillermo C. Bazan",
                "org": ""
            },
            {
                "name": "Yong Cao",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Lab Specially Functional Materials and Advanced Manufacturing Technology, South China University of Technology, Guangzhou 510640, People’s Republic of China"
            }
        ],
        "venue": "Organic Electronics",
        "year": 2009
    },
    "gYZ5K7Db": {
        "id": "gYZ5K7Db",
        "title": "High-efficiency and good color quality white light-emitting devices based on polymer blend",
        "abstract": "Here we report efficient and color-stable white polymer light-emitting devices (WPLEDs) based on a newly synthesized efficient blue emitting polymer poly[(9,9-bis(4-(2-ethylhexyloxy)phenyl)fluorene)- co -(3,7-dibenziothiene-S,S-dioxide10)] (PPF-3,7SO10) which dually function as host material and blue emitter, with appropriate blending ratio with two typical electroluminescent polymers, green emitting poly[2-(4-(3′,7′-dimethyloctyloxy)-phenyl)- p -phenylenevinylene] (P-PPV) and orange–red emitter poly[2-methoxy-5-(2′-ethyl-hexyloxy)-1,4-phenylene vinylene] (MEH–PPV) with appropriate blending ratio. In a single active layer WPLEDs with a blending ratio of 100:0.8:0.5 (B:G:R) by weight, white light emission with CIE coordinate of (0.34, 0.35) was realized. The resulted device shows a high luminous efficiency (LE) of 8.7 cd A −1 , which could be further enhanced to 14.0 cd A −1 with incorporation of a thin hole transporting layer poly (vinylcarbazole) (PVK) at the anode side. The obtained luminous efficiency is listed as one of the highest reported value for WPLEDs based on all fluorescent polymer emitters. The devices had appropriate color temperature of 2500–6500 K and high color rendering index (CRI) of 72–79, and are characterized with stable electroluminescent spectra upon change of current density, stress and annealing at high temperature, thus can find application in solid-state lighting. PACS 85.60.Jb 78.60.Fi Keywords White polymer light-emitting devices Deep-blue emitter Polyfluorene derivatives 1 Introduction White organic light-emitting diodes (WOLEDs) have attracted considerable attention due to their potential applications in backlight for liquid crystal display, and light sources for indoor lighting. Many approaches to realize white emission in organic LEDs have been reported, including blending emissive polymers with different emission color [1–3] , doping with phosphorescent complexes or fluorescent dyes into small molecule or polymer host [4–11] , exciplex in bilayers structure [12,13] , multiple component emissive layers containing an appropriate ratio of red, green and blue (RGB) phosphorescent [5,14] or fluorescent dopants [3] , multilayer structure [15] and single polymer with functional groups [16–18] . Among these approaches, devices based on polymer materials or solution-processed technology, named polymer light-emitting devices (PLEDs) [3,5–9] are of particular interest due to their potential advantages such as low-cost of manufacturing large area size, the compatibility with flexible substrates, relative small amount of wasted materials and easily controllable doping levels. However, in most of the reported efficient WPLEDs, triplet emitter with sky-blue emission was used as a key component to fabricate phosphor-based device despite their relative poor color quality [5–9] . Besides, unstable PVK was used as host material in these devices, which would degrade significantly during operation, thus limit their practical applications. In order to overcome this problem and obtain efficient WPLEDs with high color quality and long-term stability, an alternative approach is to use efficient deep-blue polymer as both host material and blue emitter to fabricate multiple dopants all-polymer WPLEDs. So far, polyfluorenes (PFs) and its derivatives are the most frequently used deep-blue polymer for WPLEDs although their luminous efficiency is typically between 1 and 2 cd A −1 , making the efficiency of WPLEDs based on these polymers rarely exceed 10 cd A −1 [15] . Therefore, it is expected that the efficiency of all-polymer WPLEDs can be significantly enhanced if more efficient blue emitter be used in these devices. In this paper, we report realization of efficient WPLEDs with good color quality based on blending of fluorescent polymers with RGB emission covering the entire visible spectrum. The polymers used here include, a newly synthesized efficient deep-blue emitting polyfluorene derivative named poly[(9,9-bis(4-(2-ethylhexyloxy)phenyl)fluorene)- co -(3,7-dibenziothiene-S,S-dioxide10)] (PPF-3,7SO10) [19] , a green light-emitting poly[2-(4-(3′,7′-dimethyloctyloxy)-phenyl)- p -phenylenevinylene] (P-PPV) and an orange–red light-emitting 2-methoxy-5-(2′-ethyl-hexyloxy)-1, 4-phenylenevinylene (MEH–PPV), respectively. Optimized device shows a peak luminous efficiency of 14.0 cd A −1 and a peak power efficiency of 7.6 lm W −1 , with a CIE of (0.33, 0.35) at a current density of 10 mA cm −2 . 2 Experimental details The device structure in this study is indium tin oxide (ITO)/PEDOT:PSS/PPF-3,7SO10 (100 wt%):P-PPV ( x wt%):MEH–PPV ( y wt%)/Ba/Al, where PEDOT:PSS is poly(ethylendioxythiophene):poly(styrene sulfonic acid), purchased from H. C. Starck, Inc., while the polymers PPF-3,7SO10, P-PPV and MEH–PPV were synthesized in our laboratory and the chemical structures of these materials show in Fig. 1 . The devices were fabricated following a well-established procedure. First, a 40 nm film of PEDOT:PSS (Baytron P4083) was spin coated on a precleaned ITO substrate and baked to dry in a vacuum oven at 80 °C for 12 h. The polymer blend consisting of PPF-3,7SO10, P-PPV and MEH–PPV were spin coated from toluene solution, resulting in an emissive layer of 80 nm (as determined by a profiler, Tencor Alfa-Step 500). Finally, 4 nm barium and 120 nm aluminum layer were evaporated with a shadow mask at a base pressure of 3 × 10 −4 Pa. The thickness of the evaporated cathodes was monitored by a quartz crystal thickness/ratio monitor (Model:STM-100/MF, Sycon). The overlapping area between the cathode and anode defined a pixel size of 19 mm 2 . Except for the deposition of the PEDOT:PSS layers, all of the fabrication processes were carried out inside a controlled atmosphere of nitrogen dry-box (Vacuum Atmosphere Co.) containing less than 10 ppm oxygen and moisture. Current density ( j )–voltage ( V )–luminance ( L ) data was collected using a Keithley 236 source meter and a calibrated silicon photodiode. The EL spectra and CIE coordinate was recorded using PR-705 SpectraScan spectrophotometer (Photo Research), while the color rendering index (CRI) was calculated following the CIE publication released in 1974 [19] . After the devices were annealed atop of a hotplate at high temperature (120–200 °C) for 2–12 h, spectral stability of EL upon thermal annealing were performed in atmosphere by a PR-705 SpectraScan spectrophotometer soon after cooling down to room temperature. The stability of the white emitting PLEDs was studied in atmosphere by applying a constant current stress with an initial luminance of 1500 cd m 2 . Before annealing in atmosphere and stress test, the PLEDs were encapsulated with a UV-cured epoxy resin. 3 Results and discussion For the monochromatic devices based on MEH–PPV (red), P-PPV (green), and PPF-3,7SO10 (blue), peak LE of 2.5 cd A −1 , 22.2 cd A −1 and 5.1 cd A −1 were recorded, which corresponded to external quantum efficiencies (EQE) of 2.5%, 9.0% and 6.1%, respectively. The 1931 CIE coordinate of the RGB devices were (0.61, 0.39), (0.46, 0.52), and (0.16, 0.16), respectively. While keeping in mind the CIE coordinates of the primary RGB color system adopted by National Television System Committee (NTSC) for color TV are (0.67, 0.33) (R), (0.21, 0.71) (G) and (0.14, 0.08) (B), it can be clearly seen that the blue emitter match the NTSC best. Also, as shown in Fig. 2 , the emission of the monochromatic devices based on the RGB emitters covers the entire visible light spectrum. It is expected that white emission can be realized if emission of each color is carefully balanced. To obtain white emission with good color quality, a series of devices with various doping concentrations and ratios were fabricated and evaluated, and their device performance was summarized in Table 1 . Depending on the doping concentration, devices were referred to as device A1–device D1, with structure like ITO/PEDOT:PSS/PPF-3,7SO10 (100 wt%):P-PPV ( x wt%) and MEH–PPV ( y wt%)/Ba/Al, in which x vary within 0.5–1.0, y within 0.2–0.5. As seen from the normalized EL spectra of devices ( Fig. 3 a), three intense peaks around 450 nm 482 nm and 573 nm were clearly observed, which can be assigned to the emission from PPF-3,7SO10 and MEH–PPV, respectively. Since there is considerable overlap between the EL peak of P-PPV (550 nm) and the shoulder of PPF3, 7SO10 ( Fig. 2 ), the former is merged and could not be seen very clearly in Fig. 3 a. Device B1 (with a blend ratio of 100:0.8:0.5 between the RGB emitters) exhibit the most balanced RGB emission, with a CIE coordinate of (0.341, 0.348), very close to the equi-energy white point (0.333, 0.333). Consistent with our previous study on the blue emitter [20] , there is a considerable enhancement in LE and EQE for the white emission PLEDs when a thin layer of PVK was inserted at the anode side to facilitate hole injection and transport. The devices with PVK as anode buffer layer were denoted as device A2–D2 and their performances were also included in Table 1 for comparison. Similar to its analog device B1, device B2 had a CIE coordinate of (0.331, 0.353) also very close to the equal-energy point as device B1. It is interesting to consider the origin of the efficient white emission from this system. Two independent excitation mechanisms may occur: energy transfer from the fluorescent host to the guest materials and charge trapping at the emitter sites [5,21] . As can be seen in Fig. 4 a, there is significant overlap between the PL spectrum of PPF-3,7SO10 and the absorption of P-PPV and MEH–PPV (large overlap between the PL spectrum of P-PPV and absorption of MEH–PPV is also observed, not shown here), implying effective energy transfer from PPF-3,7SO10 to P-PPV and MEH–PPV, or from P-PPV to MEH–PPV could readily take place. However, upon blending with other emitting species, charge trapping at the low band gap emitting sites may also occur. Comparison of PL spectra ( Fig. 3 b) from the emitting layers with the EL spectra ( Fig. 3 a) of the devices reveals that the EL spectra have a much higher contribution from the narrow band gap red/green emitters, indicating that charge trapping is the dominant process [5,10] . As shown in Fig. 4 b, the HOMO energy levels for PPF-3,7SO10, P-PPV and MEH–PPV are −5.6 eV, −5.3 eV and −4.9 eV, respectively, while the lowest unoccupied molecular orbital (LUMO) are −2.8 eV, −2.9 eV and −2.9 eV, respectively. That is, the HOMO level of the low band gap emitters is above (closer to vacuum level) that of the host, while at the same time, the LUMO level of the guest is below (deeper from vacuum level) that the host. Therefore, when charge carriers are injected from electrodes, simultaneous excitation of the green and red emitting polymers via direct charge trapping could occurs as this is energetically favored [22] . Fig. 5 shows the typical current density–luminance–voltage ( J – L – V ) characteristics and luminous efficiency–power efficiency–current density ( L E– P E– J ) characteristics of device B1 and device B2. For device B1, a maximal luminous efficiency of 8.7 cd A −1 was observed at a current density of 5.5 mA cm −2 (5.4 V) with a luminance of 484 cd m −2 , while a maximal power efficiency 5.6 lm W −1 was reached at 1.2 mA cm −2 (4.5 V). It is important to note that the turn-on voltage (defined as the voltage at which a luminance of 1 cd m −2 is reached) of device is as low as 3.0 V, which is very helpful to reduce power consumption and obtain high power efficiency. With increasing current density, the device retains high efficiency. For example, at a current density of 120 mA cm −2 , the LE is 7.0 cd A −1 , only 20 % roll-off from its peak, corresponding to a luminance of 8480 cd m −2 . As shown in Fig. 5 , for device B2, a maximal LE of 14.0 cd A −1 and a maximal EQE of 6.9% can be obtained at a current density of 1.0 mA cm −2 (the maximal power efficiency 7.6 lm W −1 was reached at 0.18 mA cm −2 ). It exhibited a turn-on voltage of 5.7 V and a maximum brightness of 20546 cd m −2 at 454 mA cm −2 . At a luminance of practical applications for solid-state lighting (SSL) application, for example, 1000 cd m −2 , good forward viewing LE and PE values are maintained: 12.5 cd A −1 , 3.7 lm W −1 at 8.9 mA cm −2 and 9.6 V for device B2. As shown in Table 1 , most of the white emission devices had appropriate color temperature (as measured as correlated color temperature (CCT) within 2500–6500 K and relative higher color rendering index (CRI) suitable for solid-state lighting. At a current density of 10 mA cm −2 , the CRI were 72 and 79 for device B1 and device B2, respectively, representing a good color quality for white lighting source. Spectral stability upon change of current density, thermal annealing and stress was also studied. When the current density varied from 2.5 mA cm −2 to 210 mA cm −2 , as shown in Fig. 6 a, the emission color of a typical device B2 did not change much, which is important for illumination. And the CIE coordinates of the white light emission showed a slight change from (0.31, 0.35) to (0.34, 0.36), still close to the white equivalent-energy point of (0.33, 0.33). Fig. 6 b showed the EL spectra of device B2 annealed at 80, 120, 160 and 200 °C for 2 h, and 120 °C for 12 h, respectively. It is important to note that the emission color remained nearly unchanged even high temperature was applied, in consistent with what was found in our previous report on the blue emitter [19] . Moreover, the evolution of spectral stability under continuous stress was also carried out with an initial luminance of 1500 cd m −2 for device B2. As revealed in Fig. 6 c, there is no obvious change with variation of the operating time up to 60 min. Thus, the device B2 represented a good spectral stability upon operational stress, indicating good device stability can be obtained in this white system. It is important to note that, much longer lifetime can be expected if the initial luminance be set as a typical luminance of 100 cd m −2 and a more reliable encapsulation technology was used. 4 Conclusions In summary, we report white polymer light-emitting devices with both high efficiency and good color quality, stability based on a newly synthesized efficient blue emitting polymer which dually functions as host material and blue emitter, with appropriate blending ratio with two typical electroluminescent polymers, green emitting P-PPV and orange–red emitter MEH–PPV. Optimized device shows a peak LE of 14.0 cd A −1 (corresponding to an EQE of 6.9%) with a CIE of (0.33, 0.35) at a current density of 10 mA cm −2 . Furthermore, our devices are characterized by very good color quality, both in term of color rending index (∼79) and color temperature 2800–6600 K), suitable for solid-state lighting applications. Upon change of current density, continuous operation and annealing at high temperature, the EL spectra shows negligible change, indicating good device stability can be obtained in this system. Acknowledgements The authors are grateful to the Natural Science Foundation of China (Project No. 2009CB623602 and U0634003) for financial support. References [1] B. Hu F. Karasz J. Appl. Phys. 93 2003 1995 [2] Q.J. Sun J.H. Hou C.H. Yang Y.F. Li Y. Yang Appl. Phys. Lett. 89 2006 153501 [3] Q.L. Niu Y.H. Xu J.B. Peng J. Lumin. 126 2007 531 [4] Y.H. Xu J.B. Peng J.X. Jiang W. Xu W. Yang Y. Cao Appl. Phys. Lett. 87 2005 193502 [5] H.B. Wu J.H. Zou F. Liu A. Mikhailovsky G.C. Bazan W. Yang Y. Cao Adv. Mater. 20 2008 696 [6] Y. Zhang F. Huang Y. Chi A.K.-Y. Jen Adv. Mater. 20 2008 1565 [7] F. Huang P.-I. Shih C.-F. Shu Y. Chi A.K.-Y. Jen Adv. Mater. 21 2009 361 [8] D. An J.H. Zou H.B. Wu J.B. Peng W. Yang Y. Cao Org. Electron. 10 2009 299 [9] Y.H. Xu R.Q. Yang J.B. Peng A. Milhailovski Y. Cao T.-Q. Nguyen G.C. Bazan Adv. Mater. 21 2009 584 [10] X. Gong W. Ma J.C. Ostrowski G.C. Bazan D. Moses A.J. Heeger Adv. Mater. 16 2004 615 [11] G. Tu Q. Zhou Y. Cheng L. Wang D. Ma X. Jing F. Wang Appl. Phys. Lett. 85 2004 2172 [12] M. Mazzeo D. Pisignano F. Della Sala J. Thompson R.I.R. Blyth G. Gigli R. Cingolani G. Sotgiu G. Barbarella Appl. Phys. Lett. 82 2003 334 [13] Q.J. Sun B.H. Fan Z.A. Tan C.H. Yang Y.F. Li Y. Yang Appl. Phys. Lett. 88 2006 163510 [14] Y.H. Xu J.B. Peng Y.Q. Mo Q. Hou Y. Cao Appl. Phys. Lett. 86 2005 163502 [15] X. Gong S. Wang D. Moses G.C. Bazan A.J. Heeger Adv. Mater. 17 2005 2053 [16] J. Liu Q.G. Zhou Y.X. Cheng Y.H. Geng L.X. Wang D.G. Ma X.B. Jing F.S. Wang Adv. Mater. 17 2005 2974 [17] J. Liu Z.Y. Xie Y.X. Cheng Y.H. Geng L.X. Wang X.B. Jing F.S. Wang Adv. Mater. 19 2007 531 [18] J. Liu Y.X. Cheng Z.Y. Xie Y.H. Geng L.X. Wang X.B. Jing F.S. Wang Adv. Mater. 20 2008 1357 [19] “Method of measuring and specifying colour rendering properties of light sources”. Publication CIE no. 13.2, Bureau Central de la CIE, Paris, 1974. [20] J. Liu J.H. Zou W. Yang H.B. Wu C. Li B. Zhang J.B. Peng Y. Cao Chem. Mater. 20 2008 4499 [21] B.W. D’Andrade R.J. Holmes S.R. Forrest Adv. Mater. 16 2004 624 [22] X. Gong J.C. Ostrowski D. Moses G.C. Bazan A.L. Heeger Adv. Funct. Mater. 13 2003 439",
        "keywords": [
            "deep-blue emitter",
            "polyfluorene derivatives",
            "white polymer light-emitting devices",
            "current density",
            "transport layer",
            "solid state lighting",
            "electroluminescence",
            "polymer blend",
            "color rendering index"
        ],
        "authors": [
            {
                "name": "Jianhua Zou",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Laboratory of Specially Functional Materials of the Ministry of Education, South China University of Technology, 381 Wushan Road, Guangzhou 510640, PR China"
            },
            {
                "name": "Jie Liu",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Laboratory of Specially Functional Materials of the Ministry of Education, South China University of Technology, 381 Wushan Road, Guangzhou 510640, PR China"
            },
            {
                "name": "Hongbin Wu",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Laboratory of Specially Functional Materials of the Ministry of Education, South China University of Technology, 381 Wushan Road, Guangzhou 510640, PR China"
            },
            {
                "name": "Junbiao Peng",
                "org": ""
            },
            {
                "name": "Yong Cao",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Laboratory of Specially Functional Materials of the Ministry of Education, South China University of Technology, 381 Wushan Road, Guangzhou 510640, PR China"
            }
        ],
        "venue": "Organic Electronics",
        "year": 2009
    },
    "fuD2Ynbj": {
        "id": "fuD2Ynbj",
        "title": "An ionic molecular glass as electron injection layer for efficient polymer light-emitting diode.",
        "abstract": "An ionic molecular glass based on a dendronized monoammonium salt has been facilely synthesized and utilized as an interfacial electron-injection layer in a light-emitting diode (LED). The characterization of a yellow-green LED that involves an Al cathode and a thin layer of the new compound spin cast from a methanol solution has shown device performances comparable to those obtained with a Ba/Al cathode. Photovoltaic measurements under white light irradiation reveal that a thin layer of the new compound can significantly increase the built-in potential and thus facilitate electron injection from an Al cathode. Furthermore, it is interesting to observe that the new ionic salt could undergo reorganization on the emissive conjugated polymer layer, which leads to the formation of nearly uniform nanoaggregates.",
        "keywords": [
            "alcohol solubility",
            "light-emitting diodes (leds)",
            "organic glass",
            "high work function cathodes",
            "conjugated polymers",
            "electron injection",
            "light emitting diode"
        ],
        "authors": [
            {
                "name": "Gang Liu",
                "org": ""
            },
            {
                "name": "Ai-Yuan Li",
                "org": ""
            },
            {
                "name": "Ding An",
                "org": ""
            },
            {
                "name": "Hong-Bin Wu",
                "org": ""
            },
            {
                "name": "Xu-Hui Zhu",
                "org": ""
            },
            {
                "name": "Yuan Li",
                "org": ""
            },
            {
                "name": "Xin-Rui Miao",
                "org": ""
            },
            {
                "name": "Wen-Li Deng",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Yong Cao",
                "org": ""
            },
            {
                "name": "Jean Roncali",
                "org": ""
            }
        ],
        "venue": "Macromolecular rapid communications",
        "year": 2009
    },
    "Yeqkn49J": {
        "id": "Yeqkn49J",
        "title": "Novel orange-red light-emitting polymers with cyclometaled iridium complex grafted in alkyl chain",
        "abstract": "Novel poly(fluorene- alt -carbazole) (PFCz) based copolymers with 3,6-carbazole- N -alkyl grafted iridium complex using 2,3-diphenylpyrazine as ligand (IrBpz) were synthesized by Suzuki polycondensation. The emission of host polymer, PFCz, was completely quenched when the copolymer with 1 mol% of iridium complex. An orange-red emission with CIE coordinate of (0.56, 0.42) was observed from Phosphorescent polymer light-emitting diodes (PhPLEDs). The PhPLEDs made by this copolymer–iridium complex showed a maximum luminous efficiency (LE) of 5.58 cd/A and a maximal luminance of 8625 cd/m 2 . White light with CIE coordinate of (0.33, 0.27) was observed from white PhPLEDs (WPhPLEDs) made by the copolymer containing 0.4 mol% iridium complex. A LE of 2.30 cd/A with luminance of 2068 cd/m 2 was observed from WPhPLEDs. Keywords Fluorene- alt -carbazole copolymer Ir complex Light-emitting diode (LED) 1 Introduction Phosphorescent polymer light-emitting diodes (PhPLEDs) have been attracted the attention of scientist during last decade because their internal quantum efficiency is theoretically 100% and they can be fabricated by low-cost wet process techniques [1,2] . In General, the emissive layer of PhPLEDs was fabricated by conjugated polymers blended with phosphorescent dyes [3] . These PhPLEDs exhibited high luminous efficiency (LE) and high brightness, however, these PhPLEDs are unstable because phase separation and triplet–triplet annihilation at the bias of high current densities. In order to resolve this problem, an alternative approach is to fabricate PhPLEDs by conjugated polymers chemically bonded with phosphorescent dyes, i.e. to copolymerize phosphorescent dyes in conjugated polymer backbone [4] or to graft phosphorescent dyes into polymer side chain by a long alkyl chain [5] . These conjugated polymers containing phosphorescent dyes allow for the formation of well-designed solid-state materials while the phase separation or dopant aggregation could be restrained and the PhPLEDs with high LE and brightness are expected. Among PhPLEDs, white PhPLEDs (WPhPLEDs) are of particular interests because their potential applications in full-color flat panel displays and solid state lighting sources [6] . Various approaches including a simultaneously incorporating three primary colors (red, green and blue) [7] or two complementary colors [8] into one polymer main chain have been reported to realize WPhPLEDs by one conjugated polymers containing phosphorescent dyes in polymer main chain. Recently, our group reported the poly(2,7-fluorene- alt -3,6-carbazole) (PFCz) derivatives with phosphorescent iridium complexes in polymer side chain [9] . In these new materials, the emission from the host PFCz is completely quenched by the incorporated iridium complexes, and emissions of these polymers are mainly relied on the incorporated iridium complexes [10] . In this paper, we reported the synthesis of PFCz–IrBpz, an iridium(III)bis(2,3-diphenylpyrazine-N,C 2′ )-2,4-pentadiketone (IrBpz) as an phosphorescent dyes chemically bonded with PFCz side chain by alkyl side chain. We demonstrated that the PhPLEDs with CIE coordinate of (0.56, 0.42) and a LE of 5.58 cd/A due to the emission of IrBpz from PFCz–IrBpz was observed by carefully tune the content of IrBpz in PFCz. Moreover, WPhPLEDs with CIE coordinate of (0.33, 0.27) and a LE of 2.30 cd/A was achieved from PFCz–IrBpz via further tuning the content of IrBpz in PFCz to realize the emission from PFCz and IrBpz. 2 Results and discussion 2.1 Synthesis of monomers and polymers The ligand 2,3-diphenylpyrazine ( 2 ) was prepared in high yield from dehydration of 2,3-diphenyl-5,6-dihydropyrazine ( 1 ) with FeCl 3 in dehydrate ethanol. By treatment of the bisenolate of 2,4-pentanedione with 3,6-dibromo-9-(10′-bromodecane)carbazole with sodium hydro in absolute THF, the β-diketone was successfully tethered into the side chain of carbazole- N of compound 5 by long alkyl chain with 70% yield. The reaction of the β-diketone ligand 5 with the crude chloro-bridged iridium dimer 3 in 2-ethoxyethanol under reflux for 16 h given the 3,6-dibromocarbazole- N -decamethylene-tethered iridium complex ( 6 ) a yield of 38%. The model iridium complex 4 was synthesized in similar yield from this approach, and the yield was still as low as 42%. The synthetic routes of these compounds are shown in Scheme 1 . The reason for the low yield might be attribute to the side reaction of generated hydrodebrominated derivatives, which has been previously evidenced by Evans et al. [11] . Although the yield was much lower than expectation, the 1 H NMR spectrum of the 3,6-dibromocarbazole- N -decamethylene-tethered iridium complex ( 6 ) was well accordance with the target molecular structure while only a trace of impurities was found. Molecular structure of 6 was further verified by the data from both ESI-MS and elemental analysis. In addition, a 1 H– 1 H COSY spectrum enables the near-complete assignment of all aromatic protons for the 3,6-dibromocarbazole- N -decamethylene-tethered iridium complex ( 6 ) in deuterated chloroform except the detailed splitting of protons in pyrazine ligand (adjacent to the aromatic phenyl carbon atoms which coordinated with iridium core), which might caused by face-to-face conformation of the iridium complex. Combining the integral values of each of the peaks in the one-dimensional 1 H NMR spectrum and the coherence peaks of protons coupled over two (geminal) or three (vicinal) bonds in 1 H– 1 H COSY spectrum, the assignment along with the protons chemical shifts of complex 6 is attained and the results are shown in Fig. 1 . The copolymers were prepared from 3,6-dibromo-9-(iridium(III)bis(2,3-diphenylpyrazine-N,C 2′ ))-12,14-pentadecyldiketone)carbazole ( 6 ), 3,6-dibromo-9-(2-ethylhexyl)-carbazole [12] ( 7 ), and 2,7-bis(4,4,5,5-tetramethyl-1,3,2-dixaborolan-2-yl)-9,9-dioctylfluorene [13] ( 8 ) by Suzuki polycondensation ( Scheme 1 ). At the end of the polymerization, phenylboric acid and bromobenzene are added subsequently to remove the possible ended bromo- or boric ester groups in the resulted polymers. The feed ratio of Ir complex in the polycondensation are 0, 0.2, 0.4, 0.6, 1 and 2 mol%, and the corresponding copolymers are named PFCz, PFCzIrBpz-02, PFCzIrBpz-04, PFCzIrBpz-06, PFCzIrBpz-1 and PFCzIrBpz-2, respectively. Average molecular weights ( M n ) of these copolymers are from 8200 to 10 200 with the polydispersity (PDI) in the range of 1.6–2.0, which is consistent with the Suzuki polycondesation procedure [14] (see Table 1 ). 2.2 Photophysical and electrochemical properties Fig. 2 shows the UV–vis absorption spectra of copolymer PFCzIrBpz and Ir complex (IrBpz) and the PL spectrum of PFCz. It was found that all of these copolymers have very similar UV–vis spectra, and the characteristic absorption of IrBpz cannot be observed because of their fairly low content level in copolymers. The model Ir complex (IrBpz) has broad absorption band ranged from 270 nm to 570 nm. An intense absorption band below 350 nm is attributed to the spin-allowed singlet state 1 π–π ∗ transition of cyclometalated ligands. A weak absorption band around 410 nm is assigned to the spin-allowed singlet metal-to-ligand charge-transfer ( 1 MLCT) transition. The strong absorption peaked at 512 nm for IrBpz is originated from triplet metal-to-ligand change-transfer ( 3 MLCT) transition. Fig. 2 shows clearly that there is a good spectral overlap between the PL emission of the host copolymer PFCz and the absorption spectra of the guests (IrBpz) which was shown clearly in Fig. 1 . This good spectra overlap indicated an efficient Förster energy transfer from the PFCz host to Ir complex guests is expected [14] . The electrochemical behaviors of copolymers were investigated by cyclic voltammetry (CV) in 0.1 M of tetrabutylammonium hexafluorophosphate (Bu 4 NPF 6 ) acetonitrile (CH 3 CN) solution. The CV curves were referred to an Ag quasireference electrode, which was calibrated using the ferrocene/ferrocenium redox couple (0.35 V vs. Ag/AgCl) as an internal standard prior to measurements. The photophysical and electrochemical properties of Ir complexes and the redox potentials of copolymers derived from the onset in the cyclic voltammetry are summarized in Table 1 . The HOMO energy levels of polymers can be estimated using the empirical equation E HOMO = −e( E ox + 4.40) (eV) [15] . However, since the redox peaks cannot be recorded corresponding to Ir complex in the copolymers, so the LUMO energy levels ( E LUMO ) is estimated from both of the absorption onset (the optical energy gap, E opt g ) and E HOMO . The oxidation for IrBpz observed at 0.96 V, thus the HOMO energy level of IrBpz was calculated as −5.26 eV, which was slight lower than that of PEDOT:PSS (−5.20 eV) but higher than that of host PFCz (−5.47 eV). The LUMO energy level ( E LUMO ) was estimated to be −3.08 eV based on E HOMO and corresponding optical band gap ( E g opt ) . In considering that the iridium complex (IrBpz) was tethered to PFCz side chain by a long alkyl spacer, thus its E HOMO and E LUMO would not distinctly change. In this case, both of the E HOMO and E LUMO would fall within that of PFCz, so that the grafted IrBpz is expected to function as both hole and electron trapping center. The photoluminescent (PL) spectra of the copolymers were shown in Fig. 3 . All of the emissions of copolymers are dominant at 420 with a small shoulder at 585 nm. The emission peaked at 420 nm is attributed to the emission of host PFCz, while the 585 nm peaks are ascribed to the emission of grafted IrBpz complex. The relative intensities at 420 nm remain almost independent with the Ir complex (IrBpz) contents in the copolymers and the emission at 585 nm increased gradually with the grafted IrBpz contents. The PL quantum efficiencies of PFCz–IrBpz and PFCzIrBpz are in the range of 45–60%. 2.3 Electroluminescent properties In order to balance the carrier’s transporting, 30 wt% of 2- tert -butylphenyl-5-biphenyl-1,3,4-oxadiazole (PBD) was blended with the copolymers to make in the emissive layer because copolymer exhibited a good hole transport property due to the incorporated carbazole moiety into main chain of polymer, and PBD is well-know electron transporting molecule [16] . The electroluminescent (EL) spectra observed from the devices with a configuration of ITO/PEDOT:PSS (40 nm)/polymer + PBD (30 wt%) (80 nm)/Ba (4 nm)/Al (150 nm) were shown in Fig. 4 . Unlike the PL spectra, the emission from host PFCz was completely quenched when the content of IrBpz reaches 1 mol%. The substantial differences in PL and EL indicated that the operational mechanisms in PL and EL were different. The HOMO and LUMO of the grafted iridium complex IrBpz were within the band gap of the host copolymer (PFCz) (whose HOMO and LUMO are −5.47 and −2.27 eV, respectively). Therefore, the injected hole from the anode and the electron from the cathode should be readily trapped by the grafted Ir complex sites [17] . In other words, the grafted Ir complexes functioned as both hole and electron trapping centers and dominated electrical excitation processes in the devices. The EL spectra shown in Fig. 4 further demonstrated that when the content of the grafted IrBpz is larger than 1 mol%, the EL emission from host PFCz was completely quenched. However, the dominated electrical excitation processes in the devices can be tuned if the content of the grafted iridium complex were controlled at a certain level [10] . Two simultaneously emissions both from PFCz (blue emission) and IrBpz (orange-red emission) are expected. In order to obtain white light form PFCz–IrBpz via combination blue emission from PFCz and organe-red emission from IrBpz, we synthesized PFCzIrBpz04, where the content IrBpz is as low as 0.4 mol%. The EL spectra observed from PhPLEDs made by PFCzIrBpz-04 shown two peaks. The blue emission was from PFCz fluorescent and the orange-red emission, peaked at 585 nm) was from IrBpz phosphorescent. Observed white light has CIE of (0.33, 0.27) which is very close to that from pure white light (0.33, 0.33). The observed CIE coordinates were shown in Fig. 5 . The devices performances were summarized in Table 2 . The applied voltages from these devices made by various copolymers were relatively low. This was probably due to the incorporated carbazole moiety in main chain of polymer resulting in high HOMO as compared with polyfluorene homopolymers. The best device performance was observed from PhPLEDs made by PFCzIrBpz-1. The light observed from this device has a CIE coordinate of (0.56, 0.42). The devices exhibited a maximum LE of 5.58 cd/A with brightness of 8625 cd/m 2 at current density of 7.7 mA/cm 2 . The device performance became poor when a high content of IrBpz was incorporated with copolymers. However, the white light was observed from PhPLED made by PFCzIrBpz-04. The white light has CIE coordinate of (0.33, 0.27). The WPhPLEDs exhibited a LE max of 2.30 cd/A and brightness of 2068 cd/m 2 at current density of 8.7 mA/cm 2 . We also observed a stable color when PhPLEDs and WPhPLEDs were biased at different current densities. For the fabricated WPhPLEDs based on PFCzIrBpz-04 as active layer, the CIE coordinates varied from (0.33, 0.27) to (0.34, 0.25) while the corresponding current density increased from 5 mA/cm 2 to 100 mA/cm 2 . These results demonstrated that the graft of phosphorescent complexes by long alkyl side chain into polymer backbone is an effective approach to obtain stable white light from WPhPLEDs, particularly, at the bias of high current density [18] . 3 Conclusion Electrophosphorescent polymers grafted iridium complex by a long alkyl chain were synthesized by Suzuki polycondensation. The orange-red light with a CIE coordinate of (0.56, 0.42) was observed from PhPLEDs made by copolymer with 1 mol% IrBpz into PFCz. The PhPLEDs exhibited a LE of 5.6 cd/A. White light with a CIE coordinate of (0.33, 0.27) was observed from WPhPLEDs made by a copolymer of PFCzIrVpz-04, in which the content of IrBpz was tuned to be 0.4% into PFCz. WPhPLEDs exhibited a LE of 2.30 cd/A and stabilized white light at the bias of high current densities. All these results demonstrated that semiconducting polymer containing metal complex is an efficiency approach to realize high performance PhPLEDs and WPhPLEDs. 4 Experimental 4.1 Materials and characterization All manipulations involving air-sensitive reagents were performed under an atmosphere of dry argon. All reagents, unless otherwise specified, were obtained from Aldrich, Acros, and TCI Co. and were used as received. 3,6-Dibromo-9-(2-ethylhexyl)-carbazole [15] , 2,7-bis(4,4,5,5-tetramethyl-1,3,2-dixaborolan-2-yl)-9,9-dioctylfluorene [15] , 3,6-dibromo-9-(12,14-pentadecyldiketone)carbazole [13] and poly(fluorene- alt -carbazole) (PFCz) were synthesized according to similar reported procedures. 1 H and 13 C NMR spectra were recorded on a Bruker DRX 300 spectrometer operating respectively at 300 and 75 MHz, with tetramethylsilane (TMS) as a reference. The H,H-COSY spectrum was recorded and processed in the absolute value mode 10. The spectral width was 5208.33 Hz; 8 accumulations, 1 K × 400 data points ( t 2 × t 1 ). The data point array was F 2 × F 1 = 1 K × 1 K for Fourier transformation after zero filling. The probe temperature was regulated at 298 K. Direct injection mass spectra were recorded by the electron spray impact (ESI) method on a LCQ DECA XP Liquid Chromatography–Mass Spectrometer (Thremo Co.). Molecular weight determination was obtained using a Waters GPC 2410 in tetrahydrofuran via a calibration curve of polystyrene standards. Elemental analyses were performed on Vario EL Elemental analysis instrument (Elementar Co.). Samples were pressed as homogeneous tablets ( = 30 mm) of compressed (375 MPa) powder of the copolymers. UV–vis absorption spectra were recorded on a HP 8453 spectrophotometer. The PL quantum yields were determined in an integrating sphere ISO80 (Labsphere) with 325 nm excitation of HeCd laser (Mells Griot). Cyclic voltammetry was carried out on a potentiostat/galvanostat model at a scan rate of 50 mV/s against Ag/AgCl reference electrode with nitrogen-saturated solution of 0.1 M tetrabutylammonium hexafluorophosphate (Bu 4 NPF 6 ) in acetonitrile (CH 3 CN). Element analyses were performed on Vario EL Elemental analysis instrument (Elementar Company). 4.2 Device fabrication and characterization Polymers were dissolved in p -xylene and filtered with a 0.45 μm PTFE filter. Patterned ITO coated glass substrates were cleaned with acetone, detergent, distilled water and 2-propanol followed by in an ultrasonic bath. After treated with oxygen plasma, 50 nm of poly(3,4-ethylenedioxythiophene) doped with poly(styrenesulfonic acid) (PEDOT:PSS, Batron-P 4083, Bayer AG) was spin-coated onto the ITO substrates followed by drying in a vacuum oven at 80 °C for 8 h. A thin film of polymers was coated onto the resulting PEDOT:PSS layer by spin-casting inside a glove box filled with nitrogen. The film thickness of the active layers was around 75–80 nm, as determined with an Alfa Step 500 surface profiler (Tencor). Current–Voltage ( I – V ) characteristics were recorded with a Keithley 236 source meter. EL spectra were obtained by Oriel Instaspec IV CCD spectrograph. Luminance was measured by a calibrated silicon photodiode and calibrated by a photometer (PR705, Photo Research). The external quantum efficiency was determined by a calibrated silicon photodiode in an integrating sphere (ISO80, Labsphere). 4.3 Synthesis of monomers 4.3.1 Synthesis of 2,3-diphenyl-5,6-dihydropyrazine ( 1 ) First, with the use of 300 ml of dehydrated ethanol as a solvent, 21.0 g (100 mmol) of benzyl and 6.1 g (101 mmol) of ethylenediamine are held at reflux in a nitrogen atmosphere for 6 h. Then the solution is condensed to one fifth, and a produced precipitation is collected. By washing the obtained precipitation with cool ethanol, the light-yellow powder is obtained (yield: 78%). 1 H NMR (300 MHz, CDCl 3 ) δ (ppm): 7.43–7.37 (m, 4H), 7.34–7.20 (m, 6H), 3.70 (s, 4H). 13 C NMR (75 MHz, CDCl 3 ) δ (ppm): 160.30, 137.78, 129.64, 128.39, 127.91, 45.84. Elemental Anal. Calc. for C 16 H 14 N 2 : C, 82.02; H, 6.02; N, 11.96. Found: C, 82.32; H, 5.92; N, 11.76%. 4.3.2 Synthesis of 2,3-diphenylpyrazine (Bpz, 2 ) 2,3-Diphenyl-5,6-dihydropyrazine ( 4 , 10 g, 27 mmol) was put into a 500 ml three neck flask, and 100 ml of dehydrate ethanol was added to be dissolved. Then, iron (III) chloride (8.8 g, 54 mmol) of was added thereto, and this mixture was heated and stirred for 30 min at 60 °C to be reacted. After the reaction, 300 ml of water was added to the reaction mixture and the precipitated solid was filtered followed by dissolved in toluene. After this mixture was washed with saturated saline, the solid was obtained by concentrating the solvent and purified by silica column chromatography. The eluent was concentrated to obtain 6.3 g of an orange solid of product in the yield of 60%. 1 H NMR (300 MHz, CDCl 3 ) δ (ppm): 8.60 (s, 2H), 7.47–7.42 (m, 4H), 7.33–7.29 (m, 6H). 13 C NMR (75 MHz, CDCl 3 ) δ (ppm): 152.84, 142.11, 138.62, 129.66, 128.69, 128.30. Elemental Anal. Calc. for C 16 H 12 N 2 : C, 82.73; H, 5.21; N, 12.06. Found: C, 82.62; H, 5.39; N, 11.98%. 4.3.3 Synthesis of chloride-bridged dimer [Ir(Bpz) 2 Cl] 2 ( 3 ) First, with the use of a mixture of 30 ml of 2-ethoxyethanol and 10 ml of water as a solvent, 1.86 g of the ligand 2,3-diphenylpyrazine ( 5 ) and 0.96 g of iridium chloride (IrCl 3 3H 2 O) are mixed in 100 ml of flask with magnetic strirrer. Then the mixture was held at reflux for 17 h in a nitrogen atmosphere to obtain a dinuclear complex [Ir(Bpz) 2 Cl] 2 (brown powder, yield: 35%). The product was used directly for the next step without further purification. 1 H NMR (300 MHz, CDCl 3 ) δ (ppm): 8.80 (d, J = 3.24 Hz, 4H), 8.26 (d, J = 3.18 Hz, 4H), 7.75 (d, J = 3.48 Hz, 8H), 7.40 (m, 12H), 6.74 (d, J = 7.95 Hz, 4H), 6.58 (td, J = 1.26 Hz and 6.72 Hz, 4H), 6.46 (t, J = 7.98 Hz, 4H), 6.02 (t, J = 7.26 Hz, 4H). 4.3.4 Synthesis of iridium(III)bis(2,3-diphenylpyrazine-N,C 2′ )-2,4-pentadiketone (IrBpz, 4 ) Chloride-bridged dimer [Ir(Bpz) 2 Cl] 2 ( 3 ) (0.45 g, 0.345 mmol), 2,4-pentadiketone (0.09 g, 0.885 mmol), and sodium carbonate (0.1 g) were mixed and refluxed in 2-ethoxylethanol (30 ml) for 16 h under a nitrogen atmosphere. The solution was cooled to room temperature and filtered before washing with water and hexane. The crude products were purified by silica chromatography (40% dichloromethane and 60% petroleum ether) with yield of 42%. 1 H NMR (300 MHz, CDCl 3 ) δ (ppm): 8.50 (dd, J = 0.72 Hz and 3.15 Hz, 2H), 8.33 (d, J = 3.15 Hz, 2H), 7.69 (m, 4H), 7.52 (m, 6H), 6.86 (d, J = 8.07 Hz, 2H), 6.67 (t, J = 7.38 Hz, 2H), 6.49 (t, J = 8.04 Hz, 2H), 6.36 (d, J = 7.62 Hz, 2H), 5.29 (s, 1H), 1.87 (s, 6H). 13 C NMR (75 MHz, CDCl 3 ) δ (ppm): 185.60, 161.90, 153.31, 149.80, 142.62, 140.91, 139.91, 139.06, 132.49, 129.57, 129.49, 129.02, 128.88, 120.72, 100.73. Elemental Anal. Calc. for C 37 H 29 IrN 4 O 2 : C, 58.95; H, 3.88; N, 7.43. Found: C, 58.83; H, 3.60; N, 7.60%. 4.3.5 Synthesis of 3,6-dibromo-9-(12,14-pentadecyldiketone)carbazole ( 5 ) In a 50 ml two-neck flask with magnetic stirrer, sodium hydride (60% dispersion in mineral oil; 320 mg, 8.00 mmol) was washed thoroughly with tetrahydrofuran (THF) under protection of argon to remove the mineral oil, and 20 ml THF was then added to the flask. Subsequently, 2,4-pentanedione (0.80 ml, 7.8 mmol) was added dropwise over 20 min to a stirred suspension of the sodium hydride in THF (20 ml) at 0 °C. The resultant mixture was stirred for 30 min at 0 °C. n -Butyllithium (2.5 M in hexane; 4.9 ml, 7.8 mmol) was added dropwise over 20 min to the stirred mixture at 0 °C. The resultant solution was stirred for 25 min at 0 °C. A solution of 3,6-dibromo-9-(10′-bromodecane)carbazole (1.62 g, 2.58 mmol) in THF (5 ml) was added dropwise over 10 min to the stirred solution at 0 °C. The resultant mixture was stirred for 1 h at 0 °C and for a further 1 h at room temperature, after which it was quenched with aqueous ammonium chloride (10 wt%, 8 ml). The mixture was acidified with concentrated hydrochloric acid to pH 1 and the aqueous phase was separated and extracted with diethyl ether. The combined organic phases were washed with saturated aqueous sodium bicarbonate, dried with anhydrous magnesium sulfate and evaporated under reduced pressure. The crude product was purified by silica chromatography using petroleum ether/ethyl acetate as eluent to give the tethered ligand as white solid in yield of 70%. 1 H NMR (300 MHz, CDCl 3 ) δ (ppm): 15.51 (s, 1H, enolone 3-H3), 8.13 (d, J = 1.89 Hz, 2H), 7.54 (dd, J = 1.89 Hz and 8.70 Hz, 2H), 7.27 (d, J = 8.70 Hz, 2H), 5.48 (s, 0.8H, enolone 3-H), 4.23(t, J = 7.14 Hz, 2H), 3.56 (s, 0.4 H, dione 3-H2), 2.49 (t, J = 7.32 Hz, 0.4 H, dione 5-H2), 2.24 (t, J = 7.41 Hz, 1.6 H, enolone 5-H2), 2.23 (s, 0.6 H, dione 1-H3), 2.05 (s, 2.4H, enolone 1-H3), 1.81 (m, 2H), 1.57 (m, 2H), 1.42–1.25 (m, 14H). 13 C NMR (75 MHz, CDCl 3 ) δ (ppm): 194.32, 191.41, 139.31, 129.00, 123.44, 123.25, 111.93, 110.40, 99.76, 43.34, 38.27, 29.42, 29.39, 29.34, 29.28, 29.21, 29.18, 28.83, 27.19, 25.68, 24.99. Elemental Anal. Calc. for C 27 H 33 Br 2 NO 2 : C, 57.56; H, 5.90; N, 2.49. Found: C, 57.29; H, 6.00; N, 2.52%. 4.3.6 Synthesis of 3,6-dibromo-9-(iridium(III)bis(2,3-diphenylpyrazine-N,C 2′ ))-12,14-pentade- cyldiketone)carbazole ( 6 ) Chloride-bridged dimer [Ir(Bpz) 2 Cl] 2 ( 3 ) (0.45 g, 0.345 mmol), 3,6-dibromo-9-(12,14-pentadecyldiketone)carbazole ( 5 , 0.54 g, 0.885 mmol), and sodium carbonate (0.1 g) were mixed and refluxed in 2-ethoxylethanol (30 ml) for 16 h under a nitrogen atmosphere. The solution was cooled to room temperature and filtered before washing with water and hexane. The crude products were purified by silica chromatography (40% dichloromethane and 60% petroleum ether) with yield of 38%. 1 H NMR (300 MHz, CDCl 3 ) δ (ppm): 8.48 (dd, J = 2.04 Hz and 3.06 Hz, 2H), 8.30 (dd, J = 1.14 Hz and 3.12 Hz, 2H), 8.14 (d, J = 1.86 Hz, 2H), 7.70 (m, 4H), 7.56-7.47 (m, 8H), 7.25 (d, J = 8.70 Hz, 2H), 6.85 (dt, J = 1.20 Hz and 5.94 Hz, 2H), 6.66 (tt, J = 0.90 Hz and 7.20 Hz, 2H), 6.52-6.45 (m, 2H), 6.42 (dd, J = 0.72 Hz and 7.56 Hz, 1H), 6.34 (dd, J = 0.66 Hz and 7.53 Hz, 1H), 5.26 (s, 1H), 4.23 (t, J = 7.14 Hz, 2H), 2.05 (t, J = 7.32 Hz, 2H), 1.88 (s, 3H), 1.80 (m, 2H), 1.37-1.06 (m, 16H). 13 C NMR (75 MHz, CDCl 3 ) δ (ppm): 189.17, 185.72, 161.96, 161.82, 153.31, 153.21, 150.26, 149.99, 142.54, 140.80, 140.74, 139.90, 139.34, 139.05, 139.02, 132.85, 132.57, 129.56, 129.53, 129.35, 129.02, 128.88, 128.75, 123.47, 123.28, 120.68, 120.63, 111.95, 110.41, 43.36, 41.77, 31.89, 29.44, 29.40, 29.36, 29.32, 29.29, 29.07, 28.88, 28.83, 27.33, 27.18, 22.66, 14.11. Elemental Anal. Calc. for C 59 H 54 Br 2 IrN 5 O 2 : C, 58.22; H, 4.47; N, 5.75. Found: C, 58.46; H, 4.70; N, 5.60%. ESI-MS ( m / z ): 1218.4. 4.3.7 General procedure for Suzuki polycondensation of copolymers PFCzIrBpz, taking PFCzIrBpz-1 as an example 3,6-Dibromo-9-(2-ethylhexyl)carbazole ( 7 , 268.7 mg, 0.495 mmol), 2,7-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-9,9-dioctylfluorene ( 8 , 321.3 mg, 0.5 mmol), 3,6-dibromo-9-(iridium(III)bis(2,3-diphenylpyrazine-N,C 2′ ))-12,14-pentadecyldiketone)carbazole ( 6 , 6.6 mg, 0.005 mmol), palladium(II) acetate (Pd(OAc) 2 , 1.5 mol% equivalent) and tricyclohexylphosphine (P(Cyh) 3 , 4 mol% equivalent) were dissolved in the mixture of toluene (8 ml), after stirred for 0.5 h, deionized H 2 O (2 ml) and Et 4 NOH (35 wt%) aqueous solution (0.2 ml) was added. The mixture was heated to 90 °C and stirred for 48 h under argon atmosphere. Then the reaction was capped by adding phenyl boric acid (25 mg) by stirring for 12 h to remove the bromine end groups, and then bromobenzene (1 ml) was added as a mono functional end-capping reagent by heating for another 12 h to remove the resident boronic ester end groups. The whole mixture was poured into methanol. The precipitated polymer was recovered by filtration and purified by silica column chromatography with toluene as eluent to remove small molecular fraction and residue catalyst (yield 69%). 1 H NMR (300 MHz, CDCl 3 ) δ (ppm): 8.54 (br, 2H), 7.86 (br, 2H), 7.78 (br, 2H), 7.73 (br, 2H), 7.56 (m, 2H), 7.24 (m, 2H), 4.32 (m, 2H), 2.10 (m, 1H), 1.95 (m, 4H), 1.52–0.78 (m, 44H). Acknowledgements We thank the National Natural Science Foundation of China (No. 20574021 and U0634003), and the Ministry of Science and Technology of China (Project No. 2009CB613403) for the financial support. References [1] [a] M.A. Baldo D.F. O’Brien Y. You A. Shoustikov S. Sibley M.E. Thompson S.R. 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Polym. Sci. A: Polym. Chem. 46 2008 453 [b] C.Y. Mei J.Q. Ding B. Yao Y.X. Cheng Z.Y. Xie Y.H. Geng L.X. Wang J. Polym. Sci. A: Polym. Chem. 45 2007 1746 [11] N.R. Evans L.S. Devi C.S.K. Mak S.E. Watkins S.I. Pascu A. Kohler R.H. Friend C.K. Williams A.B. Holmes J. Am. Chem. Soc. 128 2006 6647 [12] J. Huang Y.H. Niu W. Yang Y.Q. Mo M. Yuan Y. Cao Macromolecules 35 2002 6080 [13] W. Yang Q. Hou C.Z. Liu Y.H. Niu J. Huang R.Q. Yang Y. Cao J. Mater. Chem. 13 2003 1351 [14] X. Gong J.C. Ostrowski D. Moses G.C. Bazan A.J. Heeger Adv. Funct. Mater. 13 2003 439 [15] J.L. Bredas R. Silbey D.S. Boudreaux R.R. Chance J. Am. Chem. Soc. 105 1983 6555 [16] S. Lamansky P.I. Djurovich F.A. Razzaq S.G. aron D.L. Murphy M.E. Thompson J. Appl. Phys. 92 2002 1570 [17] P.A. Lane L.C. Palilis D.F. O’Brien C. Giebeler A.J. Cadby D.G. Lidzey A.J. Campbell W. Blau D.D.C. Bradley Phys. Rev. B 63 2001 235206 [18] Y.C. Chen G.S. Huang C.C. Hsiao S.A. Chen J. Am. Chem. Soc. 128 2006 8549",
        "keywords": [
            "fluorene-alt-carbazole copolymer",
            "ir complex",
            "light-emitting diode (led)",
            "light emitting diode"
        ],
        "authors": [
            {
                "name": "Lei Ying",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Laboratory of Specially Functional Materials, Ministry of Education, South China University of Technology, Guangzhou 510640, China"
            },
            {
                "name": "Jianhua Zou",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Laboratory of Specially Functional Materials, Ministry of Education, South China University of Technology, Guangzhou 510640, China"
            },
            {
                "name": "Anqi Zhang",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Laboratory of Specially Functional Materials, Ministry of Education, South China University of Technology, Guangzhou 510640, China"
            },
            {
                "name": "Bing Chen",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Laboratory of Specially Functional Materials, Ministry of Education, South China University of Technology, Guangzhou 510640, China"
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Yong Cao",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Laboratory of Specially Functional Materials, Ministry of Education, South China University of Technology, Guangzhou 510640, China"
            }
        ],
        "venue": "Journal of Organometallic Chemistry",
        "year": 2009
    },
    "4bLK4kZi": {
        "id": "4bLK4kZi",
        "title": "Anionic triphenylamine- and fluorene-based conjugated polyelectrolyte as a hole-transporting material for polymer light-emitting diodes",
        "abstract": "",
        "keywords": [
            "hole transport",
            "polyelectrolyte",
            "polymeric light-emitting diode",
            "triphenylamine",
            "light emitting diode"
        ],
        "authors": [
            {
                "name": "Wei Shi",
                "org": ""
            },
            {
                "name": "Lei Wang",
                "org": ""
            },
            {
                "name": "Fei Huang",
                "org": ""
            },
            {
                "name": "Ransheng Liu",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Yong Cao",
                "org": ""
            }
        ],
        "venue": "Polymer International",
        "year": 2009
    },
    "jGJd83rO": {
        "id": "jGJd83rO",
        "title": "SYNTHESIS AND APPLICATIONS OF SULFONATE-SUBSTITUTED,TRIPHENYLAMINE-BASED CONJUGATED POLYELECTROLYTES",
        "abstract": "Two kinds of sulfonate-substituted,triphenylamine-based conjugated polyelectrolytes,PTP11 and PTP31 were synthesized by water-phase Suzuki coupling reaction,and the control polymer PTPOBS was prepared using the same polymerization condition for comparison.The chemical structures of these polymers were verified by NMR and elemental analyses.The maximum absorptions of PTP11,PTP31 and PTPOBS in solid state appeared in the range of 361～376 nm,with the optical bandgaps of 2.87～2.93 eV.These polymers emitted blue light under the excitation at wavelength of their absorption maximum and showed the maximum emission at the region of 445～450 nm.Investigation of the electrochemical properties of these copolymers suggests that they have HOMO levels(-5.08～-5.16 eV)closing to the work function of ITO and possess relative high-lying LUMO levels(-2.23～-2.20 eV).The solubility of these polymers is distinct from that of `neutral-charged' polymers due to the presence of anionic sulfonate groups in the side chain,thus the intermixing between hole-transport and emitting layers can be facilely avoided by choosing different solvents during the fabrication process of multilayer PLEDs.The devices' performance was remarkably enhanced when using these polyelectrolytes as hole-transport layers in PFO-DBT15 based red-emitting PLEDs,and the device performance can be influenced by the different substitution manner of sulfonate groups.The external quantum efficiency of these devices at the current density of ca.33.3 mA cm-2 slightly decreases with the increasing composition ratio of directly sulfonated triphenylamine moiety in the polymers' backbone.The better device performance was obtained by using ITO/PTPOBS as anode,with the efficiency of 1.6% and brightness of 158 cd m-2.",
        "keywords": [
            "Triphenylamine",
            "Polymeric light-emitting device",
            "Hole-transport material",
            "Conjugated polyelectrolytes"
        ],
        "authors": [
            {
                "name": "Wei SHI",
                "org": ""
            },
            {
                "name": "Suqin FAN",
                "org": ""
            },
            {
                "name": "Lei WANG",
                "org": ""
            },
            {
                "name": "Wei YANG",
                "org": ""
            },
            {
                "name": "Yong CAO",
                "org": ""
            }
        ],
        "venue": "Acta Polymerica Sinica",
        "year": 2009
    },
    "cORxKL6e": {
        "id": "cORxKL6e",
        "title": "SYNTHESIS OF (FLOURENE-<I>alt</I>-TRIPHENYLPYRIDINYL) COPOLYMERS AND THEIR PHOTOLUMINESCENCE PROPERTIES",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Yangjun XIA",
                "org": ""
            },
            {
                "name": "Zheng ZOU",
                "org": ""
            },
            {
                "name": "Shujiang ZHANG",
                "org": ""
            },
            {
                "name": "Wei YANG",
                "org": ""
            },
            {
                "name": "Yong CAO",
                "org": ""
            },
            {
                "name": "Wenkui DONG",
                "org": ""
            },
            {
                "name": "Duowang FAN",
                "org": ""
            }
        ],
        "venue": "Acta Polymerica Sinica",
        "year": 2009
    },
    "xeBBpLcT": {
        "id": "xeBBpLcT",
        "title": "Novel Red Light-Emitting Fluorene-<i>alt</i>-Carbazole Copolymers with Carbazole<i>N</i>-Graft Cyclometalated Ir Complexes",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Lei Ying",
                "org": ""
            },
            {
                "name": "Jianhua Zou",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Hongbin Wu",
                "org": ""
            },
            {
                "name": "Anqi Zhang",
                "org": ""
            },
            {
                "name": "Zhonglian Wu",
                "org": ""
            },
            {
                "name": "Yong Cao",
                "org": ""
            }
        ],
        "venue": "Macromolecular Chemistry and Physics",
        "year": 2009
    },
    "CnT9yt6R": {
        "id": "CnT9yt6R",
        "title": "Efficient red-light-emitting diodes based on novel amino-alkyl containing electrophosphorescent polyfluorenes with Al or Au as cathode",
        "abstract": "Novel amino-alkyl containing polyfluorenes with Ir complex in pendant chain were synthesized by Suzuki polycondensation and efficient red-light-emitting devices based on the polymers that were fabricated using high work-function metal (Al or Au) as cathode. It was found that the prepared polyfluorenes exhibit good device performances, and the best device efficiency was achieved based on PFN-Irpiq1 that showed a maximal quantum efficiency (QE max ) of 3.7% and 1.6% for Al and Au as cathode, respectively, which was comparable to that of 5.5% for low work-function metals Ba as cathode. The efficiencies of devices from the aforementioned polymers showed a reduced roll-off upon the increase of current density, which is beneficial for the highly efficient phosphorescent dye/host-doped systems. The obtained high efficiencies with air-stable metals as cathode reflect that the copolymers have dual functions of being efficient light-emitting and electron injection ability. The results indicated that the incorporation of Ir complex into amino-alkyl containing polyfluorenes side chain is a potential approach to achieve efficient light-emitting devices with air-stable high work-function metal as the cathode.",
        "keywords": [
            "ir complex",
            "red-light-emitting diode",
            "al or au cathode",
            "78.60.fi",
            "72.80.le",
            "amino-alkyl containing polyfluorene",
            "85.60.jb",
            "quantum efficiency",
            "current density",
            "work function"
        ],
        "authors": [
            {
                "name": "Lei Ying",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology, Key Lab of Specially Functional Materials, Ministry of Education, Guangzhou 510640, China"
            },
            {
                "name": "Yunhua Xu",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology, Key Lab of Specially Functional Materials, Ministry of Education, Guangzhou 510640, China"
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Lei Wang",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology, Key Lab of Specially Functional Materials, Ministry of Education, Guangzhou 510640, China"
            },
            {
                "name": "Hongbin Wu",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology, Key Lab of Specially Functional Materials, Ministry of Education, Guangzhou 510640, China"
            },
            {
                "name": "Yong Cao",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology, Key Lab of Specially Functional Materials, Ministry of Education, Guangzhou 510640, China"
            }
        ],
        "venue": "Organic Electronics",
        "year": 2009
    },
    "K1Kv4oPp": {
        "id": "K1Kv4oPp",
        "title": "Progress and perspective of polymer white light-emitting devices and materials.",
        "abstract": "Within organic optoelectronics, polymer light-emitting devices (PLEDs) are regarded as an important class of devices which can convert electricity into light as a result of radiative decay taking place in semiconducting polymers. Recently, much effort has been devoted to developing efficient white emitting PLEDs for their potential applications in next-generation flat-panel displays and solid-state lighting sources. In this tutorial review, we will summarize the advances in white emitting polymers and devices published up till April 2009 by major prestigious institutions in this field. Special attention is paid to the recent progress in highly efficient devices realized by doping an electrophosphorescent guest into a polymer host and other approaches. Also we will summarize the new strategies to realize white emission with simultaneous fluorescent and/or phosphorescent emission from a single polymer in which singlet and/or triplet chromophores are incorporated into the polymer side or main chain through a covalent bond.",
        "keywords": [],
        "authors": [
            {
                "name": "Hongbin Wu",
                "org": ""
            },
            {
                "name": "Lei Ying",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Yong Cao",
                "org": ""
            }
        ],
        "venue": "Chemical Society reviews",
        "year": 2009
    },
    "qTUWY2R0": {
        "id": "qTUWY2R0",
        "title": "Triphenylamine and fluorene based cationic conjugated poly electrolytes: Synthesis and characterization",
        "abstract": "Two kinds of amino-functionized, triphenylamine and fluorene based copolymers, PFT-N and PTFF-N, were synthesized by palladium-catalyzed Suzuki coupling reaction. The corresponding quaternized polyelectrolytes PFT-NBr and PTFF-NBr were obtained through post-polymerization. The quenching behaviors of PFT-NBr and PTFF-NBr in methanol were investigated by the titration of Fe(CN) 4- 6. All of these polymers were investigated as emitting layer in multilayer PLEDs. Devices' performance together with electrochemical properties of these polymers indicate that both of the hole and the electron injection capabilities of them were improved due to the simultaneous introduction of the triphenylamine segment and the aminoalkyl (ammonium) group. © 2009 WILEY-VCH Verlag GmbH & Co. KGaA.",
        "keywords": [
            "Conjugated polyelectrolytes",
            "Fluorene",
            "Polymer lightemitting device",
            "Quenching",
            "Triphenylamine"
        ],
        "authors": [
            {
                "name": "Wei Shi",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Xi Jiang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Wenjin Zen",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Fei Huang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Wei Yang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Ransheng Liu",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Yong Cao",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            }
        ],
        "venue": "Macromolecular Chemistry and Physics",
        "year": 2009
    },
    "BKxhEIds": {
        "id": "BKxhEIds",
        "title": "Novel white-light-emitting polyfluorenes with benzothiadiazole and Ir complex on the backbone",
        "abstract": "Novel white-emitting polyfluorenes were synthesized by mixing fluorescence and phosphorescence emission. Benzothiadiazole(BT) and iridium(III)bis(2-(1-naphthalene)pyridine- C 2′ , N )-2,2,6,6-tetramethyl-3,5-heptanedione[(1-npy) 2 Ir(tmd)] units were incorporated into polyfluorene backbone as green and red chromophores by Suzuki polycondensation. The device from PFG03–IrR07 shows a maximum luminous efficiency (LE) of 5.3 cd/A, a maximum luminance of 9900 cd/m 2 at a current density of 453 mA/cm 2 and a CIE coordinate of (0.32, 0.34) with the configuration: ITO/PEDOT:PSS/PVK/emissive layer/CsF/Al. Besides, the EL efficiencies decline slightly with increasing the current density. All emissions located very close to the equi-energy white point (0.33, 0.33) when applied voltage change from 9 to 14 V. Furthermore, the white emission of devices based on these materials shows very good color quality, with high color rendering index range between 84 and 89. Our results indicate that, by incorporation of singlet and triplet species into polymer backbone, the obtained white-emitting materials and devices are promising candidates for display and solid-state-lighting purpose. Graphical abstract Keywords Polyfluorene Singlet and triplet chromophores White-emitting device 1 Introduction White polymer light-emitting diodes (WPLEDs) have a great advantage of easy fabrication and processing, because it can be fabricated with wet-processes including spin coating, screen printing, and ink-jet printing techniques which are expected to be low cost in mass production [1] . Various approaches have been developed to fabricate WPLEDs. Light-emitting layers with broad emission spectra can be sought in a polymer doped with various dyes [2] , blending polymers with different emissions [3] , or a single polymer with broad emission [4] . A single polymer used as an active layer in WPLEDs has the advantages of avoiding phase separation and stable of electroluminescent (EL) spectra upon varying applied voltages [4a,b] . In early years, white-light-emitting polymer with long wavelength emission coming from aggregated states and excimer was reported by Tsai et al. [4c] and Chen et al. [4d] . Wang et al. [4a,b,e,f,g] presented a series of high efficient WPLEDs based on a single polymer with the fluorescent dyes in the conjugated polymer backbone or side chain. Recently, a new strategy was developed to realize white emission from a single conjugated polymer in which fluorescence- and phosphorescence-emitting species are incorporated. Furuta et al. [5] reported a near-white-emitting polymer with phosphorescent Pt functionalities. Jiang et al. [6] , Wang et al. [7] and Wu et al. [8] introduced iridium complexes into the side chain of conjugated polymers, while Zhen et al. [9] and Kappaun et al. [10] introduced the iridium complex into the polymer backbone. Though the efficiencies of these WPLEDs would be theoretically enhanced by introducing phosphorescence-emitting species into polymer, however, the efficiency was not high enough when compared with the devices fabricated using vacuum deposition technologies. Previously, we introduced bicycloiridium complex iridium(III)bis(2-(2′-benzo[4,5- a ]-thienyl)pyridinato-N,C 3′ )-2,2,6,6-tetramethyl-3,5-heptanedioe [(btp) 2 Ir(tmd)] into the polyfluorene(PFO) backbone and found that [(btp) 2 Ir(tmd)] peaked at 660 nm is too red for white-light-emitting polymers [9] . In this paper, phosphorescent-emitting species iridium(III)bis(2-(-naphthalene)pyridine- C 2′ , N )-2,2,6,6-tetramethyl-3,5-heptanedione [(1-npy) 2 Ir(tmd)] peaked at 625 nm and 2,1,3-benzothiadiazole (BT) units were introduced into PFO backbone. By adjusting the monomer feed ratios, the white emission from three individual emission species in a single polymer was realized. 2 Experimental section 2.1 Characterization 1 H NMR spectra were recorded on a Bruker DRX 400 spectrometer operating respectively at 400 or 300 MHz, in deuterated chloroform solution with tetramethylsilane as a reference. The molecular weight of the polymers was determined by Waters GPC 2410 in tetrahydrofuran (THF). Number–average ( M n ) and weight–average ( M w ) molecular weights were estimated by using a calibration curve of polystyrene standards. Elemental analyses were performed on Vario EL Elemental Analysis Instrument (Elementar Co.). Thermogravimetric analysis (TGA) measurements were performed on Netzsch TG 209 under N 2 at a heating rate of 20 °C/min. Differential scanning calorimetric (DSC) measurements were performed on Netzsch DSC204 under N 2 at a heating rate of 10 °C/min. Cyclic voltammetry (CV) was recorded on a computer-controlled CHI660A electrochemical workstation. The thin polymer film was coated on a platinum electrode as a working electrode at a scan rate of 50 mV/s against calomel reference electrode in a nitrogen-saturated solution of 0.1 M tetrabutylammonium hexafluorophosphate (Bu 4 NPF 6 ) in acetonitrile (CH 3 CN). Cyclic voltammetry of model compound DFBT was carried out in the fresh dichloromethane solution. HOMO and LUMO levels were calculated according to an empirical formula ( E HOMO = − e ( E ox + 4.4) (eV) and E LUMO = − e ( E red + 4.4) (eV)) with the ferrocene oxidation potential as the standard for the vacuum energy level [11] . Photoluminescence (PL) spectra of the copolymers in thin film on quartz substrate were recorded on an Instaspec IV CCD spectrophotometer (Oriel Co.) under 325 nm excitation of a HeCd laser. The quantum yields were measured using an Integrating Sphere IS080 (LabSphere) to collect the emitted light in all directions under the excitation of 325 nm line of a HeCd laser (Melles Griot). The thicknesses of the solid films, typically, were 100–200 nm. Phosphorescence spectrum of the iridium complex was determined at 77 K by Edinburgh FLSP920 Combined Fluorescence Lifetime and Steady State Spectrometer. 2.2 LED fabrication and measurement Polymers were dissolved in p -xylene and filtered with a 0.45 μm PTFE syringe filter. Patterned ITO coated glass substrates were cleaned with acetone, detergent, distilled water, and 2-propanol, subsequently in an ultrasonic bath. After treatment with oxygen plasma, 50 nm of poly(3,4-ethylenedioxythiophene) (PEDOT) doped with poly(styrenesulfonic acid) (PSS) (Batron-P 4083, Bayer AG) and a layer of poly(vinylcarbazole) (PVK, Aldrich) from 1,1,2,2,-tetrachloroethane solution were spin-coated onto the ITO substrate followed by drying in a vacuum oven at 80 °C for 8 h. A thin film of polymers was cast away onto the cleaned substrate by spin-casting in a glove box. The film thickness of the active layers was determined as 70–80 nm, measured by an Alfa Step 500 surface profiler (Tencor). After spin coating, the films were baked on a hot plate at 80 °C in inert atmosphere for half an hour to remove solvent residue. A thin layer of CsF (1 nm) and subsequent 200 nm layer of Al were thermally evaporated subsequently on the top of an EL polymer layer with a base pressure of 3 × 10 −4 Pa. Current–voltage ( I – V ) characteristics were recorded with a Keithley 236 source-measurement unit. EL spectra were obtained by Oriel Instaspec IV CCD spectrograph. Luminance was measured by a PR 705 photometer (Photo Research). The external quantum efficiencies were determined by an Si photodiode with calibration in an integrating sphere (IS080, Labsphere). 2.3 Materials All manipulations involving air-sensitive reagents were performed in the atmosphere of dry argon. The solvents (THF, toluene) were purified by routine procedure and distilled under dry argon before being used. All reagents, unless otherwise specified, were obtained from Aldrich, Chemical Co. and used as received. 2,7-Dibromo-9,9-dioctylfluorene ( 1 ), 2,7-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-9,9-dioctylfluorene ( 2 ), and 4,7-dibromo-2,1,3-benzothiadiazole(BTBr 2 ) ( 3 ) were synthesized according to the published procedures [12] . 2.3.1 5-Bromo-2-(1-naphthalene)pyridine 5-Bromo-2-(1-naphthalene)pyridine was synthesized according to the procedure as follows. 2,5-Dibromopyridine (2.37 g, 10 mmol), 1-naphthaleneboronic acid (1.72 g, 10 mmol), and tetrakis-(triphenylphosphine)palladium (0.107 g, 0.1 mmol) were dissolved in toluene (15 mL) and ethanol (5 mL). Then an aqueous solution of 2 M Na 2 CO 3 (6 mL) was added to the mixture. The result mixture was allowed to stir at 100 °C for 24 h. The reaction mixture was concentrated by evaporation of solvents, and the residue was dissolved in dichloromethane, washed with water, and dried under anhydrous sodium carbonate. After the evaporation of solvent, the obtained product was purified by column chromatography (silica gel, dichloromethane/hexane = 1:4) (yield: 70%). ( m / z ) 284. 1 H NMR (400 MHz, CDCl 3 ) δ (ppm): 8.86 (s, 1H), 8.04 (d, J = 8.6 Hz, 1H), 8.00 (d, J = 2.9 Hz, 1H), 7.96 (d, J = 3.2 Hz, 1H), 7.92 (d, J = 3.2 Hz, 1H), 7.62 (d, J = 2.6 Hz, 1H), 7.60 (d, J = 2.8 Hz, 1H), 7.50 (t, J = 6.0 Hz, 1H), 7.49 (t, J = 6.0 Hz, 1H), 7.47 (t, J = 6.0 Hz, 1H). Element Anal. Calcd for C 15 H 10 BrN (%): C, 63.38; H, 3.52; N, 4.93. Found (%): C, 63.30; H, 3.45; N, 4.98. 2.3.2 Iridium(III)bis(5-bromo-2-(1-naphthalene)pyridine-C 2′ N)-2,2,6,6-tetramethyl-3,5-heptanedione [(1-npyBr) 2 Ir(tmd)] ( 4 ) Iridium(III)bis(5-bromo-2-(1-naphthalene)pyridine- C 2′ N )-2,2,6,6-tetramethyl-3,5-heptanedione [(1-npyBr) 2 Ir(tmd)] ( 4 ) was prepared according to the published procedures [13] . Iridium trichloride hydrate (178 mg, 0.56 mmol), 5-bromo-2-(1-naphthalene)pyridine (477 mg,1.68 mmol), 2-ethoxyethanol (15 mL), and water (5 mL) were added into a three-necked flask (100 mL). The mixture was refluxed under an argon atmosphere for 24 h and then cooled to room temperature. A red precipitate was filtered and washed with water and ethanol several times. The resulted red solid was purified by recrystallization in mixture of CH 2 Cl 2 and hexane. Then the dried product (476 mg, 0.078 mmol) was mixed with 2,2,6,6-tetramethyl-3,5-heptanedione (40.5 mg, 0.22 mmol) and sodium carbonate (13 mg) in degassed 2-ethoxyethanol (8 mL) in a three-necked flask. The mixture was refluxed in an argon atmosphere for 13 h. After cooling to room temperature the red precipitate was formed. After being filtered and washed with water and methanol, the precipitate was purified by column chromatography (silica gel, dichloromethane) to get the red needle crystal product (yield: 75%). M-M(tmd), IrL 2 + = 759.2. 1 H NMR (400 MHz; CDCl 3 ) δ (ppm): 8.53 (s, 2H), 8.44 (d, J = 8.6 Hz, 2H), 8.37 (d, J = 9.0 Hz, 2H), 7.88 (d, J = 7.0 Hz, 2H), 7.65 (d, J = 8.0 Hz, 2H), 7.46 (t, J = 7.0 Hz, 2H), 7.28 (t, J = 7.8 Hz, 2H), 7.07 (d, J = 8.3 Hz, 2H), 6.52 (d, J = 8.3 Hz, 2H), 5.56 (s, 1H), 0.91 (s, 18H). Element Anal. Calcd for C 41 H 37 Br 2 IrN 2 O 2 (%): C, 52.30; H, 3.93; N, 2.98. Found (%): C, 52.12; H, 3.79; N, 3.07. 2.3.3 2-(1-Naphthalene)pyridine 2-(1-Naphthalene)pyridine was synthesized according to the procedure as follows. 2-Bromopyridine (1.58 g, 10 mmol), 1-naphthaleneboronic acid (1.72 g, 10 mmol), and tetrakis-(triphenylphosphine)palladium (0.107 g, 0.1 mmol) were dissolved in toluene (15 mL) and ethanol (5 mL). Then an aqueous solution of 2 M Na 2 CO 3 (6 mL) was added to the mixture. The resulting mixture was allowed to stir at 100 °C for 24 h. The reaction mixture was concentrated by evaporation of solvents, and the residue was dissolved in dichloromethane, washed with water, and dried under anhydrous sodium carbonate. After the evaporation of solvent, the obtained product was purified by column chromatography (silica gel, dichloromethane/hexane = 1:3) (yield: 78%). 1 H NMR (300 MHz, CDCl 3 ) δ (ppm): 8.81 (d, J = 2.8 Hz, 1H), 8.12–8.07 (m, 1H), 7.95 (d, J = 10.0 Hz, 2H), 7.82 (td, J = 7.7, 1.8 Hz, 1H), 7.63–7.45 (m, 5H), 7.35–7.31 (m, 1H). 2.3.4 Iridium(III)bis(2-(1-naphthalene)pyridine-C 2′ N)-2,2,6,6-tetramethyl-3,5-heptanedione [(1-npy) 2 Ir(tmd)] Iridium(III)bis(2-(1-naphthalene)pyridine- C 2′ N )-2,2,6,6-tetramethyl-3,5-heptanedione [(1-npy) 2 Ir(tmd)] was synthesized according to the procedure as follows. Iridium trichloride hydrate (212 mg, 0.6 mmol), 2-(1-naphthalene)pyridine (369 mg,1.8 mmol), 2-ethoxyethanol (15 mL), and water (5 mL) were added into a three-necked flask (100 mL). The mixture was refluxed under an argon atmosphere for 24 h and then cooled to room temperature. An orange precipitate was filtered and washed with water and ethanol several times. The resulted orange solid was purified by recrystallization in mixture of CH 2 Cl 2 and hexane. Then the dried product (102 mg, 0.08 mmol) was mixed with 2,2,6,6-tetramethyl-3,5-heptanedione (44.2 mg, 0.24 mmol) and sodium carbonate (13 mg) in degassed 2-ethoxyethanol (8 mL) in a three-necked flask. The mixture was refluxed in an argon atmosphere for 13 h. After cooling to room temperature the red precipitate was formed. After being filtered and washed with water and methanol, the precipitate was purified by column chromatography (silica gel, dichloromethane) to get the orange needle crystal product (yield: 60%). 1 H NMR (300 MHz; CDCl 3 ) δ (ppm): 8.56 (d, J = 8.6 Hz, 2H), 8.49 (t, J = 6.5 Hz, 4H), 7.78 (t, J = 7.9 Hz, 2H), 7.65 (d, J = 7.7 Hz, 2H), 7.47 (td, J = 7.0, 1.3 Hz, 2H), 7.25 (t, J = 7.1 Hz, 2H), 7.10–7.04 (m, 4H), 6.56 (d, J = 8.1 Hz, 2H), 5.52 (s, 1H), 0.89 (s, 18H). 2.3.5 4,7-Bis-(9,9-dioctyl-9H-fluoren-2-yl)-benzo[1,2,5]thiadiazole (DFBT) Into a flask was introduced 20 mL of toluene and 7 mL ethanol, 1.09 g of 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-9,9-dioctylfluorene(2.9 mmol), 294 mg of 4,7-dibromo-benzo[1,2,5]thiadiazole (1.1 mmol) and 4 mL of aqueous 2 M Na 2 CO 3 . This was N 2 purged for 1 h. 230 mg of tetrakistriphenylphosphine palladium (0) (0.03 mmol) then was added under a nitrogen purge. The content of the flask was refluxed for 2 days. The reaction flask was allowed to cool to RT and about 50 mL water added and the organic layer separated. The aqueous layer was extracted with 50 mL toluene. The organic layers were combined and washed successively with water twice and then dried over MgSO 4 . Concentration gave an oil which was purified by column chromatography (silica gel, dichloromethane/petroleum ether = 1:9) to give 587 mg (64% yield) green solid. 1 H NMR (300 MHz, CDCl 3 ) δ (ppm): 8.04 (d, J = 7.9 Hz, 2H), 7.96 (s, 2H), 7.88 (d, J = 7.7 Hz, 4H), 7.78 (d, J = 6.3 Hz, 2H), 7.35 (m, 6H), 2.01 (m, 8H), 1.10 (m, 48H), 0.81 (t, J = 5.9 Hz, 12H). 2.3.6 General procedure of Suzuki polycondensation taking PFG03–IrR07 as an example 2,7-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-9,9-dioctylfluorene ( 1 ) (341 mg, 0.5 mmol), 2,7-dibromo-9,9-dioctylfluorene ( 2 ) (268 mg, 0.49895 mmol), 4,7-dibromo-2,1,3-benzothiadiazole ( 3 ) (1 mL, 3 × 10 −4 M solution in tetrahydrofuran (THF)), (1-npyBr) 2 Ir(tmd) ( 4 ) (0.75 mL, 1 × 10 −3 M solution in THF), and bis(tri- o -tolyphosphine) palladium(II) dichloride (5 mg) were dissolved in the mixture of toluene/THF (15 mL), stirred for 0.5 h, and then Et 4 NOH (20%) aqueous solution (4 mL) was added. The mixture was heated to 100 °C and stirred for 2 days in an argon atmosphere. Then the polymer was capped by adding 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-9,9-dioctylfluorene (50 mg) by continuous stirring for 12 h and then bromobenzene (0.25 mL) followed by continuous reacting for another 12 h. The whole mixture was poured into methanol. The precipitated polymer was recovered by filtration and purified by silica column chromatography with toluene to remove small molecular complex and catalyst residue (yield: 50%). 1 H NMR (300 MHz, CDCl 3 ) δ (ppm): 7.85 (br, 2H), 7.78 (br s, 2H), 7.72 (br, 2H), 1.96 (m, 4H), 1.21–0.97 (m, 24H), 0.82 (br, 6H). Element Anal. Calcd (%): C, 89.16; H, 10.20; N, 0.071. Found (%): C, 88.53; H, 10.69; N, <0.3. 3 Result and discussion 3.1 Synthesis and characterization Polyfluorene (PFO), an excellent blue-light-emitting polymer, has large band gap and good electronic properties. The emission color of PFO can be tuned in entire visible region by incorporating low band gap units into the backbone or attaching emitters onto the side chain [14] . However, phosphor quenching of the triplet emitter by polyfluorene must be considered when a triplet emitter is introduced into polyfluorene. It is well known that polyfluorene possesses high singlet energy level (3.2 eV), but its triplet energy level is 2.3 eV [15] , which is lower than those of most phosphorescent materials [16] . Consequently, the fluorene-based copolymers with phosphorescent emitters usually suffer from the energy back transfer from the triplet level of guest to that of polyfluorene, leading to a serious phosphorescence quenching and poor emission property. In fact, some efficient electrophosphorescent red-light-emitting devices have been achieved based on physical- or chemical-doping PFO systems [14a,17] , but a few green and blue electrophosphorescent light-emitting devices could be achieved based on PFO systems because the triplet energy levels of both green and blue triplet emitters (>2.4 eV) are higher than that of PFO, resulting in the green emission quenching of both green and blue triplet emitters [18] . However, PFO possesses higher singlet energy level and therefore, efficient singlet energy transfer can occur from polyfluorene to singlet emitters. The efficiency enhancement was reported due to the exciton confinement of the narrow-band gap emitters [12] . In principle, to obtain efficient green emission from the fluorene-based copolymers, using fluorescent comonomers as the narrow-band gap emitters should be a good choice. Therefore, efficient white emission is expected from the fluorene-based copolymers by introducing green-fluorescent and red-phosphorescent units into the polymer backbone [19] . Fig. 1 shows the energy transfer among polyfluorene backbone, green- and red-emitting model compound 4,7-bis(9,9-dihexyl-fluoren-2-yl)-2,1,3-benzothiadiazole(DFBT) and iridium complex (1-npy) 2 Ir(tmd) in the copolymer. The singlet energy level of PFO is higher than that of DFBT and Ir complex, thus there should be cascade singlet energy transfer from PFO to both DFBT and Ir complex units. The triplet energy levels of PFO, DFBT and (1-npy) 2 Ir(tmd) are 2.3, 1.6 and 2.1 eV, respectively. Since the triplet energy levels of both DFBT and Ir complex are lower than that of PFO, thus the triplet energy back transfer from both of the DFBT and Ir compolex units to the PFO segment could be well-avoided, and the triplet exitons could be mainly confined in the Ir complex which would lead efficient phosphorescent red emission. However, it can be speculated that there should be exothermic energy transfer from Ir complex triplet state to DFBT triplet state from their triplet energy alignments, thus we suppose there should be some energy loss in a certain extent. The synthetic route of copolymers is shown in Scheme 1 . The copolymers containing fluorene, BT and Ir complex units were prepared by Suzuki polycondensation (SPC). In order to keep the blue-, green-, and red-emission balance, the monomer feed ratios of 4,7-dibromo-2,1,3-benzothiadiazole ( 3 ) and iridium(III) bis(5-bromo-2-(1-naphthalene)pyridine- C 2′ , N )-2,2,6,6-tetramethyl-3,5-heptanedione [(1-npyBr) 2 Ir(tmd)] ( 4 ) were respectively tuned from 0.02 to 0.05 mol% and 0.075 to 0.1 mol% in the polycondensation and the corresponding polymers were named as PFG02–IrR1, PFG04–IrR1, PFG05–IrR1 and PFG03–IrR07. The resulted copolymers are soluble in organic solvents and have number–average molecular weight from 23,300 to 33,700 with polydispersity index (PDI) from 1.6 to 1.8 relative to polystyrene standards. Fig. 2 shows the thermal properties of polymer PFG05–IrR1, which were evaluated by TGA and DSC measurements. The decomposition temperature ( T d ) (5% weight loss) and the glass-transition temperature ( T g ) are at 420 °C and 117 °C, respectively. Other polymers exhibit similar thermal properties as PFG05–IrR1. This means that introducing such small amount of emitter unit into polyfluorene backbone does not affect the rigidity of the resulting copolymers. 3.2 Photophysical and electrochemical properties Fig. 3 (a) shows the absorption and PL spectra of the copolymer. Compared with PFO, two distinct emissions peaked at 530 nm and 625 nm originated from BT and Ir complex moieties in the polymer backbone were observed, respectively. In Fig. 3 (b), there is good overlap between the absorption of Ir complex/BT unit and the PL spectra of PFO and BT unit in the copolymer, respectively, which implies that the efficient energy transfer, mediated by BT unit, readily occurs from the fluorene segment to the Ir compex-based moieties in the copolymer. Fig. 4 a shows the PL spectra of the copolymers with different contents of BT and Ir complex. We can see that the emission from BT unit peaked at 530 nm is much stronger than that from Ir complex although the content of BT is much lower than Ir complex, and increase with the increasing content of BT unit in copolymers. The intensity of the red emission peaked at 625 nm depends not only on the content of Ir complex but also on that of BT unit. By comparing the emissive intensities peaked at 625 nm of PFG02–IrR1 with PFG05–IrR1, the enhancement of emissive intensity of Ir complex can be observed with the increasing content of BT unit in copolymers, which indicates that the BT unit in the copolymer behaves as a bridge to provide a more efficient energy transfer from the fluorene segment to the Ir complex in the PL excitation process [22] . The light-emitting diodes were made with the configuration: ITO/PEDOT:PSS/PVK/emissive layer/CsF/Al, where poly(vinylcarbazole) (PVK) acts as a hole transport layer. In Fig. 4 b, the EL spectra of polymers show three balanced blue-, green- and red-emission peaked at 420 and 440, 520 and 625 nm, respectively. As shown in Fig. 4 , comparison of PL spectra from the emitting layers with the EL spectra of the devices reveals that the EL spectra have a much higher contribution from the BT unit and Ir complex, indicating different excitation mechanisms for PL and EL [23] . In PL process, the emission comes from segments which absorb the photon or transferred from the other excitons, so the emission intensity depends on the concentration of emitters in the copolymers. However, charge trapping makes a more important role in EL process. White emission in EL spectra can be attributed to the individual emission from blue-, green- and red-emitters with the partial energy transfer and charge trapping on the narrow-band gap units. The trapping mechanism can also be understood from the energy levels. The hole- and electron-trapping is more favorable if the highest occupied molecular orbital (HOMO) level of the guest is above (closer to the vacuum level) than that of the host, and the lowest unoccupied molecular orbital (LUMO) level of the guest is below (farther from the vacuum level) than that of the host. As determined by cyclic voltammetry (shown in Fig. 5 ), the HOMO and LUMO of PFO, DFBT and [1-(npy) 2 Ir(tmd)] are −5.8 and −2.1 eV, −5.6 and −2.9 eV, as well as −4.9 and −2.6 eV, respectively. Considering the extended conjugated length of Ir complex unit in conjugation with a neighboring conjugated segment in the polymer backbone [14b] , the actual HOMO level of Ir complex unit in the backbone should be above −4.9 eV. Therefore, HOMO and LUMO of the green DFBT and red-emitting Ir complex are within that of the blue-emitting segment (PFO). As a result, the electron injected from CsF/Al and the hole from anode are readily trapped on the site of both green- and red-emitters. In case of the combination of hole and electron at the DFBT and Ir complex, singlet and triplet excited states will be formed and the emission from DFBT and Ir complex will attribute to the overall EL emission. The same observation has also been reported in previous papers [8,24] . According to the above discussion, the EL process of the WPLEDs comprises three main mechanisms. After charges are injected into copolymers from the electrodes, some of them directly recombine on the fluorene segment to produce blue emission, and some are trapped on the DFBT and Ir complex sites to emit green- and red-light, and the others are transferred from fluorene segment to DFBT and Ir complex units to produce green- and red-emission. As a result, the broad white emission combines the emissions from the three-emitting species, fluorene segment, DFBT unit in the singlet state and Ir complex in the triplet state. By changing the contents of BT unit and Ir complex in the polymers, the EL spectra can be adjusted. When the content of BT unit as well as Ir complex in the polymers are in the region of 0.02–0.05 mol% and about 0.1 mol% respectively, the EL spectra of polymers are in the region of white emission. 3.3 Device performances Fig. 6 displays the EL spectra at different applied voltages for PFG02–IrR1 and PFG03–IrR07, respectively. With increasing of the applied voltage from 10 V to 14 V, CIE coordinates change slightly from (0.34, 0.35) to (0.32, 0.33) for PFG02–IrR1, and from (0.35, 0.36) to (0.31, 0.35) (9–13 V) for PFG03–IrR07. All of the emissions are located very close to the ideal white point (0.33, 0.33). The color shift could be attributed to the very small content of the Ir complex which readily reaches saturated status even at low bias voltage. Thus when the voltage increases, the relative intensity of red emission from the Ir complex decreased, as a result, the blue emission from fluorene segments was enhanced. However, the emission color of copolymers remains stable upon the variations of applied voltage. The enhanced stability of the white emission of a single copolymer is obviously due to the sufficient isolation of green- and red-chromophores in the polyfluorene backbone. The performances of the devices from copolymers are summarized in Table 1 . PFG02–IrR1 emits pure white light with the efficiency of 4.4 cd/A and CIE coordinates of (0.33, 0.33). The maximum luminous efficiency of 5.3 cd/A, which corresponds to an external quantum efficiency (EQE) of 2.7%, and a maximum luminance of 9900 cd/m 2 with CIE coordinates of (0.34, 0.36) were achieved for PFG03–IrR07. The devices show an appropriate color temperature, as measured by Correlated Color Temperature (CCT), of ca. 5000 K and a color rendering index (CRI) value of 88, which is important for illumination, representing good color quality for displays and solid-state lighting. Typical current density–luminance–voltage ( J – L – V ) characteristics from copolymer PFG03–IrR07 is presented in Fig. 7 (a) . The turn-on voltage (defined as the voltage where 1 cd/m 2 is measured) of 5.3 V is low among PVK-based white PLEDs, where high drive voltages are usually required because of low hole transport mobility, unmatched charge carrier injection barrier heights and charge trapping effects. The low operation voltages of the devices are important for reducing power consumption. Furthermore, the device reaches a maximum luminance of 9900 cd/m 2 at 14.3 V and 453 mA/cm 2 . As plotted in LE – J characteristics ( Fig. 7 b), the devices possess a fairly slow roll-off in efficiency loss, which can be attributed to the reducing long radiative lifetime of triplet excited states via chemical modification, otherwise multi-particle annihilation processes, such as triplet–triplet annihilation, may cause significant roll-off in efficiency at high current density region [25] . Our results indicate that the obtained white-emitting materials and devices are promising candidates for display and solid-state-lighting purpose. 4 Conclusion Efficient white emission from fluorene-based copolymers by mixing fluorescence with phosphorescence emission has been demonstrated. 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Morgado A. Charas J.A. Fernandes I.S. Goncalves L.D. Carlos L. Alcacer J Phys D Appl Phys 39 2006 3582 3587 [22] (a) M.A. Baldo M.E. Thompson S.R. Forrest Nature (London) 403 2000 750 753 (b) Y. Zhang Z. Huang W. Zeng Y. Cao Polymer 49 2008 1211 1219 [23] (a) X. Gong J.C. Ostrowski D. Moses G.C. Bazan A.J. Heeger Adv Funct Mater 13 2003 439 444 (b) P.A. Lane L.C. Palilis D.F. O'Brien J. Cadby A.J. Campbell D.D.C. Bradley Phys Rev B 63 2001 235206 235213 [24] (a) X. Gong M.R. Robinson J.C. Ostrowski D. Moses G.C. Bazan A.J. Heeger Adv Mater 14 2002 581 585 (b) C.H. Yang C.J. Bhongale C.H. Chou S.H. Yang C.N. Lo C.H. Hsu Polymer 48 2007 116 128 [25] (a) M.A. Baldo S. Lamansky P.E. Burrows M.E. Thompson S.R. Forrest Appl Phys Lett 75 1999 4 6 (b) M.A. Baldo C. Adachi S.R. Forrest Phys Rev B 62 2000 10967 10977",
        "keywords": [
            "polyfluorene",
            "singlet and triplet chromophores",
            "white-emitting device",
            "current density",
            "color rendering index",
            "solid state lighting"
        ],
        "authors": [
            {
                "name": "Qiliang Chen",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology, Key Laboratory of Specially Functional Materials, Ministry of Education, Guangzhou 510640, China"
            },
            {
                "name": "Nanliu Liu",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology, Key Laboratory of Specially Functional Materials, Ministry of Education, Guangzhou 510640, China"
            },
            {
                "name": "Lei Ying",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology, Key Laboratory of Specially Functional Materials, Ministry of Education, Guangzhou 510640, China"
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Hongbin Wu",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology, Key Laboratory of Specially Functional Materials, Ministry of Education, Guangzhou 510640, China"
            },
            {
                "name": "Wei Xu",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology, Key Laboratory of Specially Functional Materials, Ministry of Education, Guangzhou 510640, China"
            },
            {
                "name": "Yong Cao",
                "org": ""
            }
        ],
        "venue": "Polymer",
        "year": 2009
    },
    "bhjrJqlH": {
        "id": "bhjrJqlH",
        "title": "Enhanced open-circuit voltage in polymer solar cells",
        "abstract": "We reported that the open-circuit voltage (VOC) of polymer solar cells (PSCs) can be enhanced by 0.3 V via inserting a thin layer of alcohol/water-soluble polyelectrolyte between the active layer and metal electrode. The origin of the increase in VOC can be attributed to the superposition of the built-in field with the interfacial dipole of the interlayer, and the existence of the interlayer as a dielectric was confirmed by ac impedance spectroscopy. The significant enhancement in VOC and the simplicity of incorporation of interlayer by solution processing make this method a good candidate for further enhancing the performance of PSCs. © 2009 American Institute of Physics.",
        "keywords": [
            "open circuit voltage",
            "organic material",
            "water soluble",
            "impedance spectroscopy"
        ],
        "authors": [
            {
                "name": "Jie Luo",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Hongbin Wu",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Chao He",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Aiyuan Li",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Wei Yang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Yong Cao",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            }
        ],
        "venue": "Applied Physics Letters",
        "year": 2009
    },
    "X7DRmVaH": {
        "id": "X7DRmVaH",
        "title": "Novel red light-emitting fluorene-alt-carbazole copolymers with carbazole N-Graft cyclometalated Ir complexes",
        "abstract": "A series of electrophosphorescent fluorene-alt-carbazole copolymers are synthesized by Suzuki polycondensation. A β-diketone-terminated alkyl chain grafted to the N-position of carbazole serves as a ligand to form a pendant cyclometalated Ir complex with 10-methyl-dibenzo[a,c]- phenazine (Mpq), 2,3-diphenylquinoxaline (Bpq), and 1-(benzo[b]thiophen-2-yl)isoquinoline (Biq), respectively. The emission of the device of PFCzIrBiq peaked at 715 and 790 nm, which is among the deepest red emissions reported so far. The well-achieved device performances could be attributed to a combination of a higher triplet energy and suitable HOMO/LUMO energy levels which can assure efficient charge injection as a result of the incorporation of a 3,6-carbazole unit into a polyfluorene backbone. © 2009 WILEY-VCH Verlag GmbH & Co. KGaA Weinheim.",
        "keywords": [
            "fluorene-alt-carbazole",
            "graft copolymers",
            "ir complex",
            "light-emitting diodes (led)",
            "red light-emission"
        ],
        "authors": [
            {
                "name": "Lei Ying",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Jianhua Zou",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Wei Yang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "H. Wu",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Anqi Zhang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "ZhongLian Wu",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Yong Cao",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            }
        ],
        "venue": "Macromolecular Chemistry and Physics",
        "year": 2009
    },
    "Pr9gxDH4": {
        "id": "Pr9gxDH4",
        "title": "SYNTHESIS OF (FLOURENE- alt -TRIPHENYLPYRIDINYL) COPOLYMERS AND THEIR PHOTOLUMINESCENCE PROPERTIES: SYNTHESIS OF (FLOURENE- alt -TRIPHENYLPYRIDINYL) COPOLYMERS AND THEIR PHOTOLUMINESCENCE PROPERTIES",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "yangjun xia",
                "org": ""
            },
            {
                "name": "zheng zou",
                "org": ""
            },
            {
                "name": "shujiang zhang",
                "org": ""
            },
            {
                "name": "wei yang",
                "org": ""
            },
            {
                "name": "yong cao",
                "org": ""
            },
            {
                "name": "wenkui dong",
                "org": ""
            },
            {
                "name": "duowang fan",
                "org": ""
            }
        ],
        "venue": "Acta Polymerica Sinica",
        "year": 2009
    },
    "fJBmpMej": {
        "id": "fJBmpMej",
        "title": "Novel green-light-emitting hyperbranched polymers with iridium complex as core and 3,6-carbazole-co-2,6-pyridine unit as branch",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Rong Guan",
                "org": ""
            },
            {
                "name": "Yunhua Xu",
                "org": ""
            },
            {
                "name": "Lei Ying",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Hongbin Wu",
                "org": ""
            },
            {
                "name": "Qiliang Chen",
                "org": ""
            },
            {
                "name": "Yong Cao",
                "org": ""
            }
        ],
        "venue": "Journal of Materials Chemistry",
        "year": 2009
    },
    "gYR9enJF": {
        "id": "gYR9enJF",
        "title": "Synthesis and properties of aminoalkyl substituted red-emitting triphenylamine-based polymers",
        "abstract": "A series of amino-alkyl substituted, triphenylamin and fluorene-based red-emitting polymers with different feed ratios of 4, 7-di-2-thienyl-2, 1, 3-benzothiadiazole(DBT) component were synthesized by Suzuki coupling reaction. The chemical structures of these polymers were confirmed and the optoelectronic properties of them were investigated. PLEDs using these polymers as emitting-layer with high work function metal, Al, as cathode exhibited fairly good devices' performance. The device with structure of ITO/PVK/PFT-DBT-5/Al show emission peak at 647 nm, and the maximum external quantum efficiency reached 1.24%.",
        "keywords": [
            "Aminoalkyl",
            "Polymer light-emitting device",
            "Red-emitting polymer",
            "Triphenylamine"
        ],
        "authors": [
            {
                "name": "Wei Shi",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "WenJin Zeng",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Lei Wang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Yong Zhang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Wei Yang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Yong Cao",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            }
        ],
        "venue": "Gaodeng Xuexiao Huaxue Xuebao/Chemical Journal of Chinese Universities",
        "year": 2009
    },
    "uKNF6H0y": {
        "id": "uKNF6H0y",
        "title": "Synthesis and light-emitting properties of novel red electrophosphorescent fluorene-alt-carbazole copolymers",
        "abstract": "A novel monomer derived from dibromocarbazole with N-grafted with Ir complex by a long alkyl side chain was synthesized. Based on this new monomer, a series of poly (fluorene-alt-carbazole) s which tethered red light-emitting Ir complex as emitting center were synthesized with Suzuki polycondensation. The polymer light-emitting diodes with structure of ITO/PEDOT:PSS/PVK/Copolymer/Ba/Al were prepared based on the resulted copolymers. The copolymer PFCzIrNiq-1 exhibits maximal quantum efficiency of 0.23% at 9.4 mA/cm2. The peak emission of the resulted copolymers was at 680 nm, which was among the reported deepest iridium containing red-light-emitting electrophosphorescent polymers.",
        "keywords": [
            "Carbazole",
            "Copolymer",
            "Fluorene",
            "Ir complex",
            "Red-emission"
        ],
        "authors": [
            {
                "name": "Lei Ying",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Zhao Chen",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Jiaxing Jiang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Rong Guan",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Wei Yang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Yong Cao",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            }
        ],
        "venue": "Gaodeng Xuexiao Huaxue Xuebao/Chemical Journal of Chinese Universities",
        "year": 2009
    },
    "shiPNT6m": {
        "id": "shiPNT6m",
        "title": "Efficient Polymer White-Light-Emitting Devices for Solid-State Lighting",
        "abstract": "",
        "keywords": [
            "solid state lighting"
        ],
        "authors": [
            {
                "name": "Hongbin Wu",
                "org": ""
            },
            {
                "name": "Guijiang Zhou",
                "org": ""
            },
            {
                "name": "Jianhua Zou",
                "org": ""
            },
            {
                "name": "Cheuk-Lam Ho",
                "org": ""
            },
            {
                "name": "Wai-Yeung Wong",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Junbiao Peng",
                "org": ""
            },
            {
                "name": "Yong Cao",
                "org": ""
            }
        ],
        "venue": "Advanced Materials",
        "year": 2009
    },
    "gPqnCeJQ": {
        "id": "gPqnCeJQ",
        "title": "Enhancement of spectral stability and efficiency on blue light-emitters via introducing dibenzothiophene-S,S-dioxide isomers into polyfluorene backbone",
        "abstract": "Dibenzothiophene- S , S -dioxide isomer (FSO) monomers were copolymerized with extensively employed 9,9-dioctyl-2,7-fluorene monomer by Suzuki polycondensation. By introducing FSO unit into polyfluorene backbone, the spectral stability and efficiency of the blue-emitting polyfluorenes are significantly improved. All of the obtained copolymers and their devices exhibit stable photoluminescence (PL) and electroluminescence (EL) spectra, respectively, upon change of thermal annealing temperature and current densities. Furthermore green emission which is usually associated with excimer/aggregation or defects is absent in PL and EL spectra. In fact, the FSO unit acts as a deep trap for electron in the polyfluorene backbone, which could suppress the long wavelength emission. Moreover, the FSO unit lowers LUMO energy levels of the polyfluorenes, thus can maintain a balanced charge carrier injection and transport in the device based on the polymers, and therefore improves the device efficiencies. The device based on PF-2,8FSO1 and PF-3,7FSO5 show an external quantum efficiency (EQE) of 3.6% and a luminance efficiency (LE) of 3.7 cd/A with CIE coordinate of (0.16, 0.07), and an EQE of 3.8% and a LE of 4.6 cd/A with CIE coordinate of (0.15, 0.12), respectively. The results indicate that poly (dibenzothiophene- S , S -dioxide -co- 9,9-dioctyl-2,7-fluorene)s could be a promising candidate for blue-emitting polymers with spectral stability and high efficiency. PACS 85.60.jb 72.80.Le 78.60.Fi Keywords Copolymer Dibenzothiophene- S , S -dioxide Fluorene Blue light-emission Spectral stability",
        "keywords": [
            "blue light-emission",
            "copolymer",
            "dibenzothiophene-s",
            "s-dioxide",
            "fluorene",
            "spectral stability",
            "energy levels",
            "current density",
            "electroluminescence",
            "thermal annealing",
            "external quantum efficiency"
        ],
        "authors": [
            {
                "name": "Yuanyuan Li",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology, Guangzhou 510640, China"
            },
            {
                "name": "Hongbin Wu",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology, Guangzhou 510640, China"
            },
            {
                "name": "Jianhua Zou",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology, Guangzhou 510640, China"
            },
            {
                "name": "Lei Ying",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology, Guangzhou 510640, China"
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Yong Cao",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology, Guangzhou 510640, China"
            }
        ],
        "venue": "Organic Electronics",
        "year": 2009
    },
    "wUGjyjkf": {
        "id": "wUGjyjkf",
        "title": "Novel, blue light-emitting polyfluorenes containing a fluorinated quinoxaline unit",
        "abstract": "A series of fluorinated quinoxaline containing polyfluorenes were synthesized by Suzuki polycondensation. The polymer light emitting diodes based on the resulting copolymers emitted blue light, and no green emission was observed either in the photoluminescence spectra when the film had been annealed at 80–160 °C nor in the electroluminescence spectra when the current densities increased from 5 to 200 mA cm −2 . The fluorescence quantum yields decreased from 79% to 36% with increasing content of BPFQ from 1 to 20 mol%. Peak external quantum efficiency and luminous efficiency were 2.99% and 2.39 cd A −1 , respectively, with CIE coordinates of (0.16, 0.10). Keywords Fluorene Fluorinated quinoxaline Copolymer Blue light emission 1 Introduction Polymer light-emitting diodes (PLEDs) have attracting increasing interest due to their ease of fabricating large area lighting panel, and low-cost display production [1–3] . For the full color PLED applications, green and red light-emitting polymers can fulfil commercial needs while efficient and stable blue electroluminescence still remains a great challenge. Among currently available blue light-emitting polymers, poly(9,9-dialkylfluorene)s have attracted much attention because of their high photoluminescence quantum efficiencies and excellent solubility in common organic solvents [4–7] . However, the undesirable low-energy emission band located at 530–540 nm was always generated during long-term device operation. To achieve stable and pure blue electroluminescence, the incorporation of kink, heterocyclic aromatic moieties [8–15] into the polyfluorene backbone has been considered as relatively effective approaches. For example, Yang et al. [16] incorporated 3,5-pyridine to the backbone of polyfluorene, which could significantly depress the formation of excimer by controlling the chain rigidity and effective conjugation length, thereby the color purity of blue emission was distinctly enhanced. Zhu et al. [17] incorporated dibenzo[ a , c ]phenazine segments into the backbone of polyfluorenes, and achieved the efficient blue electroluminescence from intramolecular charge-transfer emission of a conjugated donor–acceptor system. However, only a few of these reported copolymers could obtain stable spectra while simultaneously achieve high efficiency. Generally, to improve light-emitting efficiency, the balance of hole and electron injected into the emitting layer is necessary [18] . Since polyfluorene was a kind of typical p-type polymer whose hole transport ability was about three orders of that of electron [19,20] , thereby introducing electron deficient n-type moiety to polymer main chain could improve electron injection and transport. Heterocyclic aromatic polyquinoxalines exhibit good electron affinity as effective n-type materials and could be employed as electron injection materials [21–26] . Kulkarni et al. [27] prepared the quinoxaline-containing polyfluorenes and obtained stable blue light-emitting devices, but the device efficiencies remained in low level and need to be further improved. It is well known that fluorinated materials exhibit high electron affinity and electron-transport capability, and could be used as n-type semiconductors in OLEDs, field-effect transistors (FETs) and thin-film transistors (TFTs) [28–30] . Sakamoto et al. [28,29] reported that the organic n-type semiconductors with improved the device performances could be obtained based on such fluorinated phenylene oligomers and dendrimers. In this contribution, we chose fluorinated monomer 2,3-bisphenyl-6-fluoroquinoxaline (BPFQ) to copolymerize with alkylfluorene essentially for the reasons that, on the one hand, the electron injection would be facilitated by the electron affinity of electron deficient BPFQ moiety; and on the other hand, the electronegative fluorine will further facilitate the electron transportation because of its strong electron-drawn properties. 2 Experimental section 2.1 Materials and measurements All manipulations involving air-sensitive reagents were performed under an atmosphere of dry argon. All reagents, unless otherwise specified, were obtained from Aldrich, Acros, and TCI Co. and were used as received. 1 H and 13 C NMR spectra were recorded on a Bruker DRX 300 spectrometer operating respectively at 300 and 75 MHz, respectively, with tetramethylsilane as a reference. Direct injection mass spectra were recorded by the electron spray impact (ESI) method on a LCQ DECA XP Liquid Chromatography–Mass Spectrometer (Thremo Co.). Glass transition temperatures ( T g s), taken as the midpoint of the change in the slope of the baseline, were measured on a TA 5200 M DSC instrument at a heating rate of 10 °C min −1 in nitrogen. Thermogravimetric analysis (TGA) of the polymers was measured on a DuPont 2000 SDT-2960 instrument at a heating rate of 20 °C min −1 in nitrogen, and T d were reported as the temperatures at 5% weight losses. Mr determination was undertaken using a Waters GPC 2410 in tetrahydrofuran using polystyrene standard calibration curves. Elemental analyses were performed on Vario EL Elemental analysis instrument (Elementar Co.). Samples were pressed as homogeneous tablets ( ∅ = 30 mm) of compressed (375 MPa) powder of the copolymers. UV–vis absorption spectra were recorded on a HP 8453 spectrophotometer. The PL quantum yields were determined in an integrating sphere ISO80 (Labsphere) with 325 nm excitation of HeCd laser (Mells Griot). Cyclic voltammetry was carried out on a CHI660A electrochemical workstation with platinum at a scan rate of 50 mV s −1 against a saturated calomel reference electrode with nitrogen-saturated solution of 0.1 M tetrabutylammonium hexafluorophosphate (Bu 4 NPF 6 ) in acetonitrile (CH 3 CN). 2.2 Device fabrication and characterization Polymers were dissolved in p -xylene and filtered with a 0.45 μm filter. Patterned ITO coated glass substrates were cleaned with acetone, detergent, distilled water and 2-propanol followed by an ultrasonic bath. After treating with oxygen plasma, 150 nm of poly(3,4-ethylenedioxythiophene) doped with poly(styrenesulfonic acid) (PEDOT:PSS, Batron-P 4083, Bayer AG) was spin-coated onto the ITO substrates followed by drying in a vacuum at 80 °C for 18 h. A thin film of polymers was coated onto the anode by spin-casting inside a dry box. The film thickness of the active layers was around 75–80 nm, measured with an Alfa Step 500 surface profiler (Tencor). A thin layer of 1,3,5-tri( N -phenyl-benzimidizol-2-yl)benzene (TPBI) (25–30 nm) and Ba (4–5 nm) was subsequently evaporated on the top of an EL polymer layer in a vacuum of 1 × 10 −4 Pa. Device performances were measured inside a dry box. Current–voltage ( I – V ) characteristics were recorded with a Keithley 236 source meter. EL spectra were obtained by Oriel Instaspec IV CCD spectrograph. Luminance was measured by a PR 705 photometer (Photo Research). The external quantum efficiencies were determined by a Si photodiode with calibration in an integrating sphere (ISO80, Labsphere). 2.3 Synthesis of monomers 2,7-Dibromo-9,9-dioctylfluorene ( 1 ) was synthesized according to reported procedures [12] . 1 H NMR (300 MHz, CDCl 3 ) δ (ppm): 7.53 (d, 2H), 7.46 (d, 2H), 7.44 (d, 2H), 1.91 (m, 4H), 1.24–1.04 (m, 20 H), 0.83 (t, 6H), 0.58 (m, 4H). 13 C NMR (75 MHz, CDCl 3 ) δ (ppm): 152.95, 139.47, 130.54, 126.57, 121.88, 121.53, 56.08, 40.52, 32.17, 31.35, 30.27, 29.54, 24.02, 23.01, 14.50. Element Anal. Calcd for C 29 H 40 Br 2 : C, 63.51%; H, 7.35%. Found: C, 63.41%; H, 6.68%. 2,7-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-9,9-dioctylfluorene ( 2 ) was synthesized according to reported procedures [12] . 1 H NMR (300 MHz, CDCl 3 ) δ (ppm): 7.81 (d, J = 7.5 Hz, 2H), 7.74 (s, 2H), 7.71 (d, J = 7.5 Hz, 2H), 1.99 (m, 4H), 1.39 (s, 24H), 1.22–1.00 (m, 20H), 0.81 (t, J = 6.8 Hz, 6H), 0.56 (m, 4H). 13 C NMR (75 MHz, CDCl 3 ) δ (ppm): 150.86, 144.30, 134.04, 129.29, 119.77, 84.11, 55.57, 40.49, 32.18, 30.33, 29.58, 25.33, 23.98, 22.99, 14.48. Element Anal. Calcd for C 41 H 64 B 2 O 4 : C, 76.64%; H, 10.04%. Found: C, 76.49%; H, 9.82%. 2,3-Bis(4-bromophenyl)-6-fluoroquinoxaline ( 3 ) . To a 100 ml flask, 4,4-dibromobenzil (1.84 g, 5 mmol) and 4-fluoro-1,2-phenylenediamine (0.70 g, 5.5 mmol) was added in 30 ml ethanol with argon purged. The mixture was heated to reflux in dark for 5 h. After the ethanol was evaporated, the crude product was separated by silica column with petrol ether/ethyl acetate of 20/1 (v/v) to give white powder in very high yield of 98%. 1 H NMR (300 MHz, CDCl 3 ) δ (ppm): 8.14 (dd, J = 5.70 Hz and 9.30 Hz, 1H), 7.77 (dd, J = 2.70 Hz and 9.30 Hz, 1H), 7.66 (td, J = 2.70 Hz and 5.70 Hz, 1H), 7.53 (d, J = 3.84 Hz, 4H), 7.40 (dd, J = 2.85 Hz and 6.18 Hz, 4H). 13 C NMR (75 MHz, CDCl 3 ) δ (ppm): 164.75, 161.40, 152.65, 151.28, 142.07, 141.89, 138.44, 138.00, 137.40, 137.30, 131.72, 131.40, 131.35, 131.22, 123.99, 123.78, 121.02, 120.67, 112.76, 112.48. EIMS: m / z 457.8 (m + 1) + . Element Anal. Calcd for C 20 H 11 Br 2 FN 2 : C, 52.43%; H, 2.42%; N, 6.11%. Found: C, 52.65%; H, 2.39%; N, 5.80%. 2.4 Polymerization 2.4.1 General procedures of Suzuki polycondensation, taking PF–BPFQ1 as an example 2,7-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-9,9-dioctylfluorene ( 2 ) (0.3213 g, 0.5 mmol), 2,3-bis(4-bromophenyl)-6-fluoroquinoxaline ( 3 ) (4.6 mg, 0.01 mmol), 2,7-dibromo-9,9-dioctylfluorene ( 1 ) (0.2687 g, 0.49 mmol), palladium(II) acetate [Pd(OAc) 2 , 1.5–2 mol% equivalent] and tricyclohexylphosphine [P(Cyh) 3 , 4–6 mol% equivalent] were dissolved in the mixture of toluene (8 ml), after stirred for 0.5 h, deionized H 2 O (2 ml) and Et 4 NOH (35 wt%) aqueous solution (0.2 ml) was added. The mixture was heated to 90 °C and stirred for 48 h under argon atmosphere. Then the reaction was capped by adding phenyl boric acid (25 mg) by stirring for 12 h to remove the bromine end groups, and then bromobenzene (1 ml) was added as a monofunctional end-capping reagent by heating for another 12 h to remove the resident boronic ester end groups. The whole mixture was poured into methanol. The precipitated polymer was recovered by filtration and purified by silica column chromatography with toluene as eluent to remove small molecular fraction and catalyst residue (yield 89%). 1 H NMR (300 MHz, CDCl 3 ) δ (ppm): 7.85 (br, 2H), 7.78 (br s, 2H), 7.72 (br, 2H), 1.96 (m, 4H), 1.21–0.97 (m, 24H), 0.82 (br, 6H). Element Anal. Calcd: C, 89.88%; H, 10.08%. Found: C, 88.28%; H, 11.60%. 3 Results and discussion 3.1 Synthesis of monomers and polymers As shown in Scheme 1 , 2,7-dibromo-9,9-dioctanefluorene ( 1 ) and 2,7-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-9,9-dioctylfluorene ( 2 ) were prepared according to reported procedures [17] . 2,3-Bis(4-bromophenyl)-6-fluoroquinoxaline ( 3 ) was facilely synthesized from 4,4′-dibromobenzil and 4-fluoro-1,2-phenyldiamine in high yield of 98%. Copolymers derived from these monomers were prepared by Suzuki polycondensation with 2:1:3 in feed ratio of 50:49:1, 50:45:5, 50:40:10 and 50:30:20, respectively, and the corresponding resulted polymers were named as PF–BPFQ1, PF–BPFQ5, PF–BPFQ10 and PF–BPFQ20. All of the resulted copolymers exhibited good solubility in common organic solvents such as toluene, chloroform and tetrahydrofuran (THF), etc. The molecular structures of the synthesized copolymers were found to be in good agreement with 1 H NMR spectra and element analysis (EA). The number average molecular weight ( M n ) of polymers estimated by gel permission chromatography (GPC) against the polystyrene standard with THF as eluent solvent ranged from 56,400 to 126,500 with a polydispersity index (PDI) ( M w / M n ) from 1.50 to 1.79, as summarized in Table 1 . 3.2 Thermal properties of polymers The thermal properties of copolymers were evaluated by DSC and TGA measurements and the data of the glass transition temperatures ( T g s) and the decomposition temperatures of 5% weight loss ( T d s) are summarized in Table 1 . As can be seen clearly from Fig. 1 , compared with the T g of PFO (67 °C), the T g s of copolymers gradually increase from 69 to 106 °C with increasing the content of BPFQ moiety from 1 to 20 mol%. Indeed, the non-linear aromatic heterocyclic BPFQ moiety could effectively hinder the motion of molecular segments, and likewise the fluorine in BPFQ could also significantly enhance the interaction among polymer backbones, thereby the T g s were distinctly improved [31] . In addition, as can be seen in Fig. 2 , all of these copolymers exhibited excellent thermal properties, with the T d of over 430 °C. 3.3 Electrochemical properties The electrochemical properties of copolymers were investigated by cyclic voltammetry, however, only the p-doping waves (oxidation potentials, E ox ) can be recorded for copolymers. The highest occupied molecular orbital (HOMO) levels were calculated according to the empirical formula E HOMO = −e( E ox + 4.4) eV and E LUMO = −e( E red + 4.4) eV [32] with the ferrocene oxidation potential as the standard for the vacuum energy level. The lowest unoccupied molecular orbital (LUMO) levels of copolymers were estimated from HOMO levels and the optical band gaps ( E g s). As can be seen from  Table 2 , with the increasing content of BPFQ unit in the copolymers, the E g s of copolymers did not change obviously while quite similar with those of PFO. However, the LUMO levels of the copolymers decreased progressively compared to the PFO, which indicated that the electron-accepting ability could be improved by introducing the electron deficient moiety into the PFO backbone. 3.4 Photophysical properties Fig. 2 illustrates the absorption spectra of copolymer in toluene solution with the concentration of 10 −5 mol L −1 (a) and in thin film (b). As shown in Fig. 3 a , the peak absorption gradually shifted from 393 nm to 380 nm with increasing the BPFQ content from 1 mol% to 20 mol%, which might attribute that the effective π-conjugated length was progressively decreased with the increasing content of BPFQ moiety. Besides, the full width at half-maximum of the absorption spectra increased with the increasing of BPFQ content, which demonstrated the greater inhomogeneous broadening owing to the local disorder induced by the kink BPFQ moiety. In addition, even though it can be seen clearly that all of the copolymers have similar absorption profile in solution and in film, there was only 4 nm shift in film when BPFQ fractions change from 1 to 20 mol%. The fact suggested that the bulk intrachain electronic delocalization for all copolymer backbone might be formed in film, given that the electron deficient BPFQ can form donor–acceptor system with p-type fluorene segments [33] . Moreover, it can be seen from Fig. 3 b that the absorption edges of the films are almost identical for all copolymers. As estimated from the band edges of absorption spectra (in film), the optical band gaps varied slightly from 2.93 to 2.97 eV. The photoluminescence (PL) spectra of copolymers in dilute toluene solution (10 −5 mol L −1 ) (a) and in film (b) are shown in Fig. 3 . The PL spectra in film were quite similar to that of in toluene solution, and all of which did not show unexpected low-energy band emission. As can be seen from Fig. 4 a , with the increasing content of BPFQ, the peak- and shoulder-emission were dominated at 417 nm and about 440 nm, respectively. However, the shoulder emission disappeared for copolymer PF–BPFQ20, and only emission at 425 nm was observed. The photophysical properties of copolymers are summarized in Table 2 . All of fluorescence quantum yields of the copolymers decreased gradually with increasing the content of BPFQ in copolymer, from 79% for PF–BPFQ1 to 36% for PF–BPFQ20. The probable reason might be the greater intramolecular charge transfer with the increasing BPFQ content [33] . In order to study thermal stabilities of PL emission of the copolymer film, we first spin-coated PEDOT onto the ITO substrate followed by drying in a vacuum oven, and a thin film of copolymer (taking PF–BPQF5 as the example) was spin-coated subsequently, and then annealed at different temperatures from 80 °C to 200 °C for 2 h, respectively in nitrogen atmosphere. As shown in Fig. 4 , the PL spectra after thermal treatment have no distinct change compared to the pristine PF–BPQF5 even when the film was annealed at temperatures much higher than its T g for 2 h. Further experiments based on the other copolymers exhibit similar results. This fact indicated that the incorporation of fluorinated quinoxaline unit into polyfluorene main chain was an effective approach to achieve stable blue emission in PL procedure. 3.5 Electroluminescent properties As can be seen from the EL spectra in Fig. 5 , no low-energy band emission was found in the EL spectra. The spectra remained blue with all of the contents of BPFQ in copolymers except a slight red-shift with the increasing content of BPFQ from 1 to 20 mol%, wherein the CIE coordinates change from (0.16, 0.07) to (0.19, 0.15). Since the electron deficient BPFQ moiety could act as charge trap unit, then the electron density of the fluorene segments were reduced and the charge delocalization in such donor–acceptor system was improved with the increasing content of BPFQ [27] followed by giving rise to a slight bathochromic shift in EL spectra. To further investigate the electroluminescent stabilities of the copolymers, the EL spectra (taking PF–BPFQ5 as the example) in different current densities were recorded. As shown in Fig. 6 , the profiles of the EL spectra only had a slight deviation with the current densities increased from 5 to 200 mA/cm 2 (corresponding applied voltages increase from 8.8 to 15.4 V, respectively), which meant the good spectra stabilities of these copolymers in EL procedure. Actually, further experiments based on the other copolymers showed similar results. The spectra stabilities might be attributed to that the electron-deficiency BPFQ moiety could withdraw the electrons from the fluorene segments, thereby even if there were a small amount of defects, the EL spectra based on these copolymers would still not be significantly influenced. With the device configuration of ITO/PEDOT/polymer/Ba/Al based on the resulted copolymers, the best device performances were attained by copolymer PF–BPFQ5 containing 5 mol% of BPFQ unit. The peak external quantum efficiency (EQE max ) and luminous efficiency (LE max ) achieved 1.17% and 0.94 cd A −1 , respectively, with CIE coordinate of (0.16, 0.08), which were very close to NTSC standard blue luminescence of (0.14, 0.08). Noted, these results were entirely based on the single layer device configuration. However unfortunately, for copolymers with BPFQ fraction exceeded 10 mol%, the comprehensive performances otherwise lowered. Taking PF–BPFQ20 as an example, the EQE max and LE max were only 0.07% and 0.05 cd A −1 , respectively. The comprehensive electroluminescent properties are summarized in Table 3 . These results clearly illustrated that there might be an optimum content for the incorporated heterocyclic BPFQ moiety. The device configuration was an important factor for device efficiency [34–36] . In considering that the LUMO energy levels of copolymers were lowered with increasing the content of BPFQ unit, it would be expected that the incorporation of BPFQ unit into polymer backbone could improve electron-accepting ability of the copolymers compared to PFO. However, given the hole transport ability of polyfluorene were almost three orders of that of electrons [19,20] , it was quite probable that only 5 mol% of BPFQ moiety in copolymer backbone was not efficient enough to transport enough electrons so as to balance the charge injection, whilst the device performances turned to inferior if extra BPFQ were incorporated. Thus, it was suspected that the charge balances of hole and electron in the emissive layer would be enhanced and the device performances would be dramatically improved if an additional hole block layer (HBL) was inserted between the emissive layer and the cathode [34] . Here, a layer of 1,3,5-tri(phenyl-2-benzimidazole)benzene (TPBI), which has comparatively deep HOMO (−6.30 eV) and favorable LUMO (−2.80 eV) energy level [37] was inserted to block the holes not being quenched in the cathode. Given the LUMO energy level of TPBI (−2.80 eV) was the same as the Ba/Al cathode (−2.80 eV) and very close to the LUMO energy level of PF–BPFQ5 (−2.82 eV) ( Fig. 7 b ), the electron injection from the cathode would not be influenced by the additional layer of TPBI. However, since there was a barrier of 0.64 eV between the HOMO of PF–BPFQ5 (−5.76 eV) and TPBI (−6.30 eV), the injected hole would be strictly confined in the emissive layer. The current density–voltage ( J – V ) characteristics and the device energy diagram ( Fig. 7 a) provided further insight into the roles played by the TPBI in the device. As can be seen from Fig. 7 a and Table 3 , the J – V characteristic shifted to a higher voltage and the device performances were obviously enhanced by insertion of a TPBI layer. The device based on PF–BPFQ5 showed an EQE max of 2.99%, and a LE max of 2.39 cd A −1 , with CIE coordinates of (0.16, 0.10). The enhanced efficiencies of the resulted devices with a TPBI layer illustrates that a more balanced hole and electron currents were achieved. Fig. 8 showed the external quantum efficiency–current density–luminance (QE– J – L ) characteristics of the devices based on PF–BPFQ1 and PF–BPFQ5, respectively. It was clearly seen that the QEs decline slightly with the increased current density, indicating that the materials and devices have a good stability. 4 Conclusion A series of novel blue light-emitting polyfluorenes were prepared via incorporating fluorinated quinoxaline unit (BPFQ) into poly(9,9-dioctyl-2,7-diyl)fluorene (PFO) backbone. The incorporated BPFQ moiety could impart copolymers good electron affinity which followed by facilitate electron injection. No green emission was observed in both PL and EL spectra of all copolymers. The devices' performances were obviously improved when TPBI was used as a hole block layer. Acknowledgement We thank the National Natural Science Foundation of China (No. 20574021, U0634003 and 50433030) for the financial support. References [1] F. Huang Y. Zhang M.S. Liu Y.J. Cheng A.K.Y. Jen High-efficiency and color stable blue-light-emitting polymers and devices Adv Funct Mater 17 2007 3808 3815 [2] S. Tang M.R. Liu P. Lu H. Xia M. Li Z.Q. Xie A molecular glass for deep-blue organic light-emitting diodes comprising a 9,9′-spirobifluorene core and peripheral carbazole groups Adv Funct Mater 17 2007 2869 2877 [3] H.B. Wu J.H. Zou F. Liu L. Wang A. Mikhailovsky G.C. 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Yang Enhancement of color purity in blue-emitting fluorene-pyridine-based copolymers by controlling the chain rigidity and effective conjugation length Polymer 45 2004 865 872 [13] F.I. Wu R. Dodda K. Jakka J.H. Huang C.S. Hsu C.F. Shu Enhancing the thermal and spectral stabilities of polyfluorene-based blue-light-emitting materials by incorporating pendent spiro-cycloalkyl groups Polymer 45 12 2004 4257 4263 [14] J. Lee H.J. Cho B.J. Jung N.S. Cho H.K. Shim Stabilized blue luminescent polyfluorenes: introducing polyhedral oligomeric silsesquioxane Macromolecules 37 23 2004 8523 8529 [15] J.Y. Li A. Ziegler G. Wegner Substituent effect to prevent autoxidation and improve spectral stability in blue light-emitting polyfluorenes Chem Eur J 11 15 2005 4450 4457 [16] W. Yang Q. Hou C.Z. Liu Y.H. Niu J. Huang R.Q. Yang Improvement of color purity in blue-emitting polyfluorene by copolymerization with dibenzothiophene J Mater Chem 13 2003 1351 1455 [17] Y. Zhu K.M. Gibbons A.P. Kulkarni S.A. 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Cheng Synthesis and properties of poly(phthalazinone ether ketone ketone)s containing pendent methyl groups Mater Sci Eng B132 2006 20 23 [32] J.L. Bredas R. Silbey D.S. Boudreaux R.R. Chance Chain-length dependence of electronic and electrochemical properties of conjugated systems: polyacetylene, polyphenylene, polythiophene, and polypyrrole J Am Chem Soc 105 1983 6555 6559 [33] S.A. Jenekhe L. Lu M.M. Alam New conjugated polymers with donor–acceptor architectures Macromolecules 34 2001 7315 7324 [34] B. Du L. Wang H.B. Wu W. Yang Y. Zhang R.S. Liu High-efficiency electrophosphorescent copolymers containing charged iridium complexes in the side chains Chem Eur J 13 2007 7432 7442 [35] H.B. Wu F. Huang Y.Q. Mo W. Yang D.L. Wang J.B. Peng Efficient electron injection from a bilayer cathode consisting of aluminum and alcohol/water-soluble conjugated polymers Adv Mater 16 2004 1826 1830 [36] W.J. Zeng H.B. Wu C. Zhang F. Huang J.B. Peng W. Yang Polymer light-emitting diodes with cathodes printed from conducting Ag paste Adv Mater 19 2007 810 814 [37] B.W. D'Andrade R.J. Holmes S.R. Forrest Efficient organic electrophosphorescent white-light-emitting device with a triple doped emissive layer Adv Mater 16 2004 624 628",
        "keywords": [
            "blue light emission",
            "copolymer",
            "fluorene",
            "fluorinated quinoxaline",
            "quantum yield",
            "light emitting diode",
            "current density",
            "electroluminescence",
            "external quantum efficiency"
        ],
        "authors": [
            {
                "name": "Lei Ying",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Lab of Specially Functional Materials, Ministry of Education, South China University of Technology, Guangzhou 510640, China"
            },
            {
                "name": "Jianhua Zou",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Lab of Specially Functional Materials, Ministry of Education, South China University of Technology, Guangzhou 510640, China"
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Anqi Zhang",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Lab of Specially Functional Materials, Ministry of Education, South China University of Technology, Guangzhou 510640, China"
            },
            {
                "name": "Zhonglian Wu",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Lab of Specially Functional Materials, Ministry of Education, South China University of Technology, Guangzhou 510640, China"
            },
            {
                "name": "Wei Zhao",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Lab of Specially Functional Materials, Ministry of Education, South China University of Technology, Guangzhou 510640, China"
            },
            {
                "name": "Yong Cao",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Lab of Specially Functional Materials, Ministry of Education, South China University of Technology, Guangzhou 510640, China"
            }
        ],
        "venue": "Dyes and Pigments",
        "year": 2009
    },
    "QDc5qqRH": {
        "id": "QDc5qqRH",
        "title": "Realization of highly efficient white polymer light-emitting devices via interfacial energy transfer from poly(N-vinylcarbazole)",
        "abstract": "We report highly efficient white polymer light-emitting devices (WPLEDs) using a newly synthesized, deep-blue emitting fluorene-co-dibenzothiophene-S,S-dioxide copolymer as host, doped with two narrow-bandgap iridium complexes. Despite the low-lying triplet energy levels of the host, phosphorescent quenching by the polyfluorene copolymer host was significantly suppressed with poly( N -vinylcarbazole) (PVK) as hole-injecting, anode buffer layer. The energy transfer process had been studied via transient photoluminescence spectra and confirmed that PVK layer is responsible for the efficient electrophosphorescence in the devices. As a result of balanced red–green–blue (RGB) emission from the host and the triplet emitters, white emission with Commission Internationale de L’Eclairage (CIE) coordinates of (0.278, 0.312) was achieved, with a peak luminous efficiency of 15.1 cd A −1 and a color rendering index (CRI) of 79–86. Keywords White polymer light-emitting devices Phosphorescence quenching Poly( N -vinylcarbazole)",
        "keywords": [
            "phosphorescence quenching",
            "poly(n-vinylcarbazole)",
            "white polymer light-emitting devices",
            "energy transfer",
            "red green blue",
            "energy levels",
            "color rendering index"
        ],
        "authors": [
            {
                "name": "Aiyuan Li",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Lab of Specially Functional Materials, Ministry of Education, South China University of Technology, Guangzhou 510640, PR China"
            },
            {
                "name": "Yuanyuan Li",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Lab of Specially Functional Materials, Ministry of Education, South China University of Technology, Guangzhou 510640, PR China"
            },
            {
                "name": "Wanzhu Cai",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Lab of Specially Functional Materials, Ministry of Education, South China University of Technology, Guangzhou 510640, PR China"
            },
            {
                "name": "Guijiang Zhou",
                "org": "Department of Chemistry, Faculty of Science, Xi’an Jiao Tong University, Xi’an 710049, PR China"
            },
            {
                "name": "Zhao Chen",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Lab of Specially Functional Materials, Ministry of Education, South China University of Technology, Guangzhou 510640, PR China"
            },
            {
                "name": "Hongbin Wu",
                "org": ""
            },
            {
                "name": "Wai-Yeung Wong",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Lab of Specially Functional Materials, Ministry of Education, South China University of Technology, Guangzhou 510640, PR China"
            },
            {
                "name": "Junbiao Peng",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Lab of Specially Functional Materials, Ministry of Education, South China University of Technology, Guangzhou 510640, PR China"
            },
            {
                "name": "Yong Cao",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Lab of Specially Functional Materials, Ministry of Education, South China University of Technology, Guangzhou 510640, PR China"
            }
        ],
        "venue": "Organic Electronics",
        "year": 2010
    },
    "IYw2g179": {
        "id": "IYw2g179",
        "title": "Effect of nonlinear liquidus and solidus on dendrite growth in bulk undercooled melts",
        "abstract": "On the base of nonlinear liquidus and solidus,an extended model for dendrite growth in bulk undercooled melts was developed under local non-equilibrium conditions both at the interface and in the bulk liquid.In terms of thermodynamic calculations of the phase diagram,the model predictions are relatively realistic physically,since few fitting parameters are used in the model predictions.Adopting three characteristic velocities,i.e.the critical velocity of absolute solute stability(VC*),the velocity of maximal tip radius(VRm),and the velocity of bulk liquid diffusion(VD),a quantitative agreement is obtained between the model predictions and the experimental results in undercooled Ni-0.7%B and Ni-1%Zr(molar fraction) alloys,and the overall solidification process can be categorized.",
        "keywords": [
            "undercooled melts",
            "dendrite growth",
            "ni-based alloys",
            "phase diagram",
            "dendritic growth",
            "thermodynamics"
        ],
        "authors": [
            {
                "name": "Zheng CHEN",
                "org": ""
            },
            {
                "name": "Hai-feng WANG",
                "org": ""
            },
            {
                "name": "Feng LIU",
                "org": ""
            },
            {
                "name": "Wei YANG",
                "org": ""
            }
        ],
        "venue": "Transactions of Nonferrous Metals Society of China",
        "year": 2010
    },
    "wr9oUb0D": {
        "id": "wr9oUb0D",
        "title": "Solute trapping model based on solute drag treatment",
        "abstract": "A solute trapping model is developed based on a so-called solute drag treatment.By adopting a basic approach of phase-field models,and defining the free energy density in the interfacial region,a suitable interface shape function is introduced to derive the current model,in which the equilibrium and non-equilibrium interface behaviours can be described using a dimensionless parameter L (i.e.an important parameter in the present interface shape function).When applying the current model to Si-9%As (molar fraction) alloy with L=0.5,a good prediction of the steeper profile for high interface velocity,which is analogous to that using a phase-field model of DANILOV and NESLTER,has been obtained.",
        "keywords": [
            "diffusive interface",
            "solute drag",
            "solute trapping",
            "free energy"
        ],
        "authors": [
            {
                "name": "Hai-feng WANG",
                "org": ""
            },
            {
                "name": "Feng LIU",
                "org": ""
            },
            {
                "name": "Zheng CHEN",
                "org": ""
            },
            {
                "name": "Wei YANG",
                "org": ""
            }
        ],
        "venue": "Transactions of Nonferrous Metals Society of China",
        "year": 2010
    },
    "6cWMLvTv": {
        "id": "6cWMLvTv",
        "title": "Pyrrole-based narrow-band-gap copolymers for red light-emitting diodes and bulk heterojunction photovoltaic cells",
        "abstract": "",
        "keywords": [
            "4",
            "7-bis(n-methylpyrrol-2-yl)-2",
            "1",
            "3-benzothiadiazole",
            "9",
            "9-dioctylfluorene",
            "light-emitting diodes",
            "solar cells",
            "light emitting diodes",
            "band gap"
        ],
        "authors": [
            {
                "name": "Mingliang Sun",
                "org": ""
            },
            {
                "name": "Li Wang",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            }
        ],
        "venue": "Journal of Applied Polymer Science",
        "year": 2010
    },
    "Y2S1vrhG": {
        "id": "Y2S1vrhG",
        "title": "Optoelectronic properties of fluorene-co-4,7-difuran-2,1,3-benzothiadiazole copolymers",
        "abstract": "Light-emitting and photovoltaic properties of copolymers (PFO-FBT) based on 9,9-dioctylfluorene and 4,7-difuran-2,1,3-benzothiadiazole\n (FBT) units were investigated. The copolymers show two absorbance peaks at around 382 nm and 530 nm, respectively. The relative\n absorbance at around 530 nm of the PFO-FBT copolymers increases with the increasing FBT content. The EL emissions are red-shifted\n from 611 nm to 702 nm by increasing the FBT content in the copolymer. The highest EL external quantum efficiency achieved\n with the device configuration of ITO/PEDOT/PVK/PFO-FBT0.1/Ba/Al is 2.32% with the luminance of 441.3 cd/m2 at a current density of 33 mA/cm2. Efficient energy transfer due to exciton trapping on low band-gap FBT sites was observed. The bulk-heterojunction photovoltaic\n cell used PFO-FBT50 copolymer as the electron donor and methanofullerene [6,6]-phenyl C61-butyric acid methyl ester (PCBM)\n as the electron acceptor shows an energy conversion efficiency of 1.13% with open-circuit voltage (V\n oc) of 0.85 V and short-circuit current density (J\n sc) of 3.39 mA/cm2 under AM 1.5 solar simulator (100 mW/cm2), and the edge of the spectral photoresponse is at ∼750 nm.",
        "keywords": [
            "copolymer",
            "photovoltaic cell",
            "photoluminescence",
            "fluorene-co-furan-benzothiadiazole",
            "short circuit current",
            "external quantum efficiency",
            "energy transfer",
            "band gap",
            "open circuit voltage",
            "energy conversion",
            "current density"
        ],
        "authors": [
            {
                "name": "Jie Luo",
                "org": "South China University of Technology Institute of Polymer Optoelectronic Material and Devices Guangzhou 510640 China"
            },
            {
                "name": "RenQiang Yang",
                "org": "Chinese Academy of Sciences Qingdao Institute of Bioenergy and Bioprocess Technology Qingdao 266101 China"
            },
            {
                "name": "Wei Yang",
                "org": "South China University of Technology Institute of Polymer Optoelectronic Material and Devices Guangzhou 510640 China"
            },
            {
                "name": "Yong Cao",
                "org": "South China University of Technology Institute of Polymer Optoelectronic Material and Devices Guangzhou 510640 China"
            }
        ],
        "venue": "Science China-chemistry",
        "year": 2010
    },
    "yxHaX3IZ": {
        "id": "yxHaX3IZ",
        "title": "ChemInform Abstract: Progress and Perspective of Polymer White Light-Emitting Devices and Materials",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Hongbin Wu",
                "org": ""
            },
            {
                "name": "Lei Ying",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Yong Cao",
                "org": ""
            }
        ],
        "venue": "Cheminform",
        "year": 2010
    },
    "v0IibahT": {
        "id": "v0IibahT",
        "title": "Novel Spectrally Stable Saturated Blue-Light-Emitting Poly[(fluorene)-<i>co</i>-(dioctyldibenzothiophene-<i>S,S</i>-dioxide)]s",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Jie Liu",
                "org": ""
            },
            {
                "name": "Sujun Hu",
                "org": ""
            },
            {
                "name": "Wei Zhao",
                "org": ""
            },
            {
                "name": "Qinghua Zou",
                "org": ""
            },
            {
                "name": "Wen Luo",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Junbiao Peng",
                "org": ""
            },
            {
                "name": "Yong Cao",
                "org": ""
            }
        ],
        "venue": "Macromolecular Rapid Communications",
        "year": 2010
    },
    "Fk8hQPSm": {
        "id": "Fk8hQPSm",
        "title": "White-Emitting Polymers and Devices",
        "abstract": "\n Interest in using white polymer light-emitting devices (WPLEDs) for flat-panel displays, back-lighting sources for liquid-crystal\n displays, and next-generation solid-state lighting sources is increasing in the past several years due to their rapid improvement\n in terms of efficiencies and color quality. In this chapter, the progress on the synthesis of white light-emitting polymers\n and the advancement of WPLEDs were summarized.\n \n ",
        "keywords": [
            "liquid crystal display",
            "solid state lighting"
        ],
        "authors": [
            {
                "name": "Hongbin Wu",
                "org": "Key Laboratory of Specially Functional Materials, Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology, Guangzhou, 510640 People’s Republic of China"
            },
            {
                "name": "Lei Ying",
                "org": "Key Laboratory of Specially Functional Materials, Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology, Guangzhou, 510640 People’s Republic of China"
            },
            {
                "name": "Wei Yang",
                "org": "Key Laboratory of Specially Functional Materials, Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology, Guangzhou, 510640 People’s Republic of China"
            },
            {
                "name": "Yong Cao",
                "org": "Key Laboratory of Specially Functional Materials, Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology, Guangzhou, 510640 People’s Republic of China"
            }
        ],
        "venue": "",
        "year": 2010
    },
    "JYE8AA45": {
        "id": "JYE8AA45",
        "title": "Polymer white light-emitting diodes with a single emission layer of fluorescent polymer blend",
        "abstract": "White polymer light-emitting diode with a single layer of fluorescent polymer blend was fabricated. The structure of the device is indium tin oxide/poly(3, 4-ethylenedioxythiophene) poly(styrenesulfonate)/emission layer/1, 3, 5-tris(N-phenylbenzimidazol-2-yl)-benzene/Ba/Al, and the emission layer is a blend of poly [2, 7-(9, 9-dioctyl)fluorene-co-2, 3-bis(4-phenyl)-6-fluoroquinoxaline] (PF-BPFQ5), phenyl-substituted poly(p-phenylene vinylene) derivative (P-PPV) and poly [2-methoxy-5-(2′-ethyl-hexyloxy)-1, 4-phenylene vinylene] (MEH-PPV), which, respectively, emits blue, green and red light. When the blend weight ratio of PF-BPFQ5:P-PPV:MEH-PPV is 100:0.6:0.6, a pure white light emission is obtained with CIE coordinates of (0.331, 0.329). The maximal luminance efficiencies is 5.64 cd/A. Meanwhile, the electroluminescence spectrum of white-light emission is stable under different current densities. © 2010 Chin. Phys. Soc.",
        "keywords": [
            "Blend",
            "Polymer light-emitting diodes",
            "White light"
        ],
        "authors": [
            {
                "name": "Wang Bao-Zheng",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Zhang An-Qi",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Wu Hong-Bin",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Wei Yang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Wen Shang-Sheng",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            }
        ],
        "venue": "Wuli Xuebao/Acta Physica Sinica",
        "year": 2010
    },
    "oeYlZT8a": {
        "id": "oeYlZT8a",
        "title": "Synthesis and electroluminescent properties of hyperbranched light-emitting polymers with iridium complex as core and 3, 6-carbazole as branch",
        "abstract": "Hyperbranched electrophosphorescent polymers, which had a core of iridium complex, 3, 6-carba-zole as branch, were synthesized by Suzuki polycondensation. The photoluminance quantum efficiency of the PCzIrMppy3 polymer was 62%, and the HOMO energy levels of the resulted polymers was -5.22 eV, respectively, which was very close to the anode ITO/PEDOT:PSS of -5.20 eV, suggesting their excellent hole inject property. The green electrophosphorescent light-emitting device based on PCzIrMppy3 polymer with structure of ITO/PEDOT:PSS/Emissive layer/CsF/Al achieved maximal luminous efficiency of 10.4 cd/A and maximal luminance of 34758 cd/m2. Besides, the device performance was isolated with respect to current density, which indicated that this kind of hyper-branched molecular structure was quite favorable for reducing triplet annihilation of electrophosphorescent copolymers at high current density.",
        "keywords": [
            "3",
            " 6-Carbazole",
            "Green light-emission",
            "Hyperbranched polymer",
            "Iridium complex"
        ],
        "authors": [
            {
                "name": "Lei Ying",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Lei Wang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "ZHANG An-Qi",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "XU Yun-Hua",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Wei Yang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Yong Cao",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            }
        ],
        "venue": "Gaodeng Xuexiao Huaxue Xuebao/Chemical Journal of Chinese Universities",
        "year": 2010
    },
    "PFn1PrS7": {
        "id": "PFn1PrS7",
        "title": "Origin of the enhanced open-circuit voltage in polymer solar cells via interfacial modification using conjugated polyelectrolytes",
        "abstract": "",
        "keywords": [
            "open circuit voltage"
        ],
        "authors": [
            {
                "name": "Chao He",
                "org": ""
            },
            {
                "name": "Chengmei Zhong",
                "org": ""
            },
            {
                "name": "Hongbin Wu",
                "org": ""
            },
            {
                "name": "Renqiang Yang",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Fei Huang",
                "org": ""
            },
            {
                "name": "Guillermo C. Bazan",
                "org": ""
            },
            {
                "name": "Yong Cao",
                "org": ""
            }
        ],
        "venue": "Journal of Materials Chemistry",
        "year": 2010
    },
    "UC3D4GHh": {
        "id": "UC3D4GHh",
        "title": "Novel conjugated alternating copolymer based on 2,7-carbazole and 2,1,3-benzoselenadiazole",
        "abstract": "A novel conjugated alternating copolymer (PCzDBSe) based on N-9′-heptadecanyl-2,7-carbazole and 5,5-(4′,7′-di-2-thienyl-2′,1′,3′-benzoselenadiazole) was synthesized by Suzuki polycondensation. The polymer reveals excellent thermal stabilities with the decomposition temperature (5% weight loss) of 390 °C and the glass-transition temperature of 140 °C. The absorption peaks of the polymer are located at 412 and 626 nm, respectively, while the absorption onset is extended to 716 nm, which is 56 nm red-shifted as compared with its analogue, poly[N-9′-heptadecanyl-2,7-carbazole-alt-5,5-(4′,7′-di-2-thienyl-2′,1′,3′-benzothiadiazole)] (PCDTBT). The HOMO and LUMO levels of the polymer were estimated to be −5.28 and −3.55 eV, respectively, with an optical bandgap of 1.73 eV. The hole mobility of PCzDBSe as deduced from a solution-processed organic field effect transistor (OFET) was found to be 3.9 × 10 −4 cm 2 V −1 s −1 . Polymer solar cells (PSCs) based on the blends of PCzDBSe and [6,6]-phenyl-C 71 -butyric acid methyl ester (PC 71 BM) with a weight ratio of 1:4 were fabricated. Under AM 1.5 (AM, air mass), 100 mW cm −2 illumination, the devices were found to have an open-circuit ( V oc ) of 0.75 V, a short-circuit current density ( J sc ) of 7.23 mA cm −2 , a fill factor (FF) of 45% and a power conversion efficiency (PCE) of 2.58%. The primary results indicate that 5,5-(4′,7′-di-2-thienyl-2′,1′,3′-benzoselenadiazole) is a promising unit for low bandgap polymer for polymer solar cells. Graphical abstract Keywords 2,7-Carbazole Benzoselenadiazole Alternating copolymer 1 Introduction Since the discovery of the ultrafast photo-induced charge transfer between conjugated polymers and fullerene, polymer solar cells (PSCs) have attracted much attention as potential large-area, flexible, and low-cost solar cells [1] . Many conjugated polymers such as poly(p-phenylenevinylene)s (PPV) [2] , poly(fluorene)s (PFO) [3] , poly(3-alkylthiophene) [4] , and polythiophene derivatives [5] were extensively studied. As a result of the development of new materials and the optimization of processing techniques, so far, the power conversion efficiency of the device based on these conjugated polymers and fullerene derivatives had exceeded 6.0% [4–7] . In order to further enhance the PCE of the polymer based solar cells, an effective method is to develop donor polymers with low bandgap to enable photocurrent generation from lower energy photons. It had been demonstrated that the incorporation of electron donating and accepting units along the polymer backbone can lead to intramolecular charge transfer thus resulting in lower bandgap polymer [8] . As compared with many other conjugated polymer donors, poly(2,7-carbazole) derivatives exhibit some unique merits such as high hole mobility, low energy lying highest occupied molecular orbital (HOMO), and therefore can result in high air stability and high V oc [9–12] . Furthermore, the absorption spectra could be easily tuned for optimal solar spectral match. In the past several years, some of the 2,7-carbazole based polymers were synthesized as donor materials for highly efficient polymer solar cells [13] , especially a low bandgap polymer, poly[N-9′-heptadecanyl-2,7-carbazole-alt-5,5-(4′,7′-di-2-thienyl-2′,1′,3′-benzothiadiazole)] (PCDTBT) with an absorption spectrum onset extended to 660 nm was reported [6,11,12,14] . Inspired by the purpose of harvesting the lower energy photons in the solar spectra, there is a need to further lower the bandgap of the 2,7-carbazole based polymer. As compared to 2,1,3-benzothiadiazole (BT), an electron deficient unit, which was widely used as the backbone in low bandgap polymers [2,3,5,15] , its analogue 2,1,3-benzoselenadiazole (BSe) is more effective in extending the absorption spectrum towards the infrared region. For example, Hou et al. demonstrated that as a result of incorporating the BSe unit in benzo[1,2-b:4,5-b]dithiophene (BDT) based polymers, the bandgaps can be lowered from 1.70 eV (BDT-BT) to 1.52 eV (BDT-BSe) [16] . In this paper, 2,7-carbazole-alt-DBSe copolymer (PCzDBSe) with an extended absorption spectrum was synthesized. The photophysical properties of the DBSe based polymer and its photovoltaic properties to act as an electron donor to PCBM were investigated and discussed. 2 Experimental section 2.1 Materials All the starting materials were purchased from Aldrich or Alfa Aesar and used without further purification. All the reactions were carried out under argon at 1 atmosphere unless mentioned otherwise. THF and CH 3 CN were distilled from sodium and CaH 2 before use, respectively. 2.2 Characterization 1 H and 13 C NMR spectra were recorded by Bruker DRX 300 and Varian INOVA 500NB spectrometers operating at 300 MHz and 125 MHz respectively, in CDCl 3 at 298 K. Chemical shifts were reported as δ values (ppm) relative to an internal tetramethylsilane (TMS) standard. The FTIR spectrum was recorded with a Bruker Vector 33 FTIR spectrometer. Elemental analysis was performed on a ELEMENTAR Vario ELIII Elemental Analyzer. Number-average ( M n ) and weight-average ( M w ) molecular weights were determined by GPC, using polystyrene as standards. Thermogravimetric analysis (TGA) was performed on Netzsch TG 209 in nitrogen, with a heating rate of 20 °C min −1 . Differential scanning calorimetry (DSC) analysis was performed on Netzsch DSC 204 in nitrogen, with a heating rate of 20 °C min −1 . Cyclic voltammograms (CV) were recorded on a CHI 660A electrochemical workstation. A conventional three-electrode system consisting of a platinum electrode as working electrode, an Ag/AgCl reference electrode and a platinum wire as counter electrode was used. The polymer film was deposited on the working electrode of platinum electrode by solvent casting. The electrode was polished by using 0.3 μm Al 2 O 3 slurry followed by rinsing with de-ionized water and acetonitrile, dried over 105 °C before use. A 0.1 M solution of tetrabutylammonium hexafluorophosphate (Bu 4 NPF 6 ) in acetonitrile was used as the supporting electrolyte. Argon was bubbled through the solution for 10 min to remove the dissolved oxygen and also over the solution throughout the experiment. Photoluminescence spectra (PL) of the polymer were recorded with a CCD spectrophotometer (Instaspec IV, Oriel Co.) under excitation of a 325 nm HeCd laser. 2.3 Fabrication and characterization of organic field effect transistor Heavily p-doped Si wafers with 600 nm thermal SiO 2 grown, were used both as the substrate and the gate electrode. The substrates were cleaned by subsequent soaking in acetone, isopropanol and de-ionized water in ultrasonic bath for 10 min, and dried with nitrogen. Then, the substrates were treated with oxygen plasma for 5 min to remove any residual organic materials and to create a high density of silanol groups at the surface. To improve the chemical and electrical properties of the gate dielectric, the SiO 2 /Si substrates were modified with a self-assembled monolayer (SAM) octyltrichlorosilane (OTS) solution in dry toluene at room temperature for 24 h. After the OTS SAM formation, the substrates were rinsed with toluene, and dried in a vacuum oven. Films of PCzDBSe were deposited on pre-treated SiO 2 /Si substrates by spin-coating a 10 mg mL −1 solution of the polymer in chlorobenzene, followed by annealing under nitrogen to remove the residual solvent. The source and drain electrodes were defined by thermally evaporating gold (70 nm) through a shadow mask on top of the organic thin film forming top contact geometry transistors. Channel length and width of the obtained OFET were 0.1 and 10 mm, respectively. The OFET was characterized under ambient conditions by a semiconductor parameter analyzer (model: 4155B). 2.4 Fabrication and characterization of polymer solar cells Patterned indium tin oxide (ITO) coated glass with a sheet resistance of 15–20 ohm/square was cleaned by a surfactant scrub, then underwent a wet-cleaning process inside an ultrasonic bath, beginning with de-ionized water, followed by acetone and isopropanol. After oxygen plasma cleaning for 5 min, a 40 nm-thick poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS) (Bayer Baytron 4083) anode buffer layer was spin-cast on the ITO substrate and then dried by baking in a vacuum oven at 80 °C overnight. The active layer, with thickness in the 60–80 nm range, was then deposited on top of the PEDOT:PSS layer, by casting from a chlorobenzene solution (20 mg mL −1 ) containing PCzDBSe:PCBM (1: x , w/w). The thickness of the PEDOT:PSS and active layer was verified by a surface profilometer (Tencor, Alpha-500). Finally, 100 nm aluminum layer was thermally evaporated with a shadow mask at a base pressure of 3 × 10 −4 Pa. The overlapping area between the cathode and anode defined a pixel size of 0.15 cm 2 . The thickness of the evaporated cathodes was monitored by a quartz crystal thickness/ratio monitor (model: STM-100/MF, Sycon). Except for the deposition of the PEDOT:PSS layers, all the fabrication processes were carried out inside a controlled atmosphere of nitrogen dry-box (Vacuum Atmosphere Co.) containing less than 10 ppm oxygen and moisture. The power conversion efficiency of the resulting polymer solar cells was measured under 1 sun AM 1.5G (air mass 1.5 global) spectrum from a solar simulator (Oriel model 91192) (1000 W m −2 ). The current density–voltage ( J – V ) characteristics were recorded with a Keithley 2410 source unit. The spectral response of the devices was measured with a commercial EQE/incident photon to charge carrier efficiency (IPCE) measurement setup (Oriel). A calibrated silicon detector was used to determine the absolute photosensitivity at different wavelengths. 2.5 Synthetic procedures 2,7-Bis(4′,4′,5′,5′-tetramethyl-1′,3′,2′-dioxaborolan-2′-yl)-N-9″-heptadecanylcarbazole [14,17] and 4,7-bis(5-bromo-2-thienyl)-2,1,3-benzoselenadiazole [18] were prepared according to the literature procedure. Synthesis of poly[N-9′-heptadecanyl-2,7-carbazole-alt-5,5-(4′,7′-di-2-thienyl-2′,1′,3′-benzoselenadiazole)](PCzDBSe). In a 50 mL flask, 328.5 mg (0.5 mmol) of 2,7-bis(4′,4′,5′,5′-tetramethyl-1′,3′,2′-dioxaborolan-2′-yl)-N-9″-heptadecanylcarbazole, 253.6 mg (0.5 mmol) of 4,7-bis(5-bromo-2-thienyl)-2,1,3-benzoselenadiazole, 3 mg (0.003 mmol) of Pd(PPh 3 ) 4 , were dissolved in 15 mL of toluene and 0.6 mL of 20% aqueous tetraethylammonium hydroxide. The reaction mixture was refluxed with vigorous stirring for 48 h under argon atmosphere. Bromobenzene (5 μL, 0.05 mmol) was added to the reaction mixture, 4 h later, phenylboronic acid (6.1 mg, 0.05 mmol) was added to the reaction mixture, and then the reaction was continued for 4 h. After cooling to room temperature, the mixture was poured into 500 mL methanol, and filtered. The precipitate was washed in a Soxhlet apparatus with hexane, acetone, toluene, dichloromethane and chloroform for 24 h, respectively. The chloroform fraction was condensed to 10 mL, and precipitated in methanol and finally dried overnight (150 mg, yield: 40%). 1 H NMR (300 MHz, CDCl 3 ) δ (ppm): 8.10 (br, 4H); 7.88 (br, 4H); 7.60 (br, 2H); 7.51 (br, 2H); 4.70 (br, 1H); 2.38 (br, 2H); 2.00 (br, 2H); 1.20 (m, 24H); 0.80 (t, 6H). 13 C NMR (125 MHz, CDCl 3 ) δ (ppm): 158.26, 157.93, 147.26, 143.11, 141.04, 139.88, 138.93, 131.93, 130.27, 128.77, 137.33, 126.62, 126.28, 125.52, 125.35, 123.93, 123.25, 122.16, 120.80, 119.50, 117.63, 117.22, 115.36, 115.03, 108.75, 106.06, 56.61, 33.89, 31.77, 29.70, 29.48, 29.35, 29.22, 26.87, 24.96, 22.59, 14.04; FTIR (KBr disk cm −1 ): 3028, 1430, 761, 722, 686, 2919, 2850. Anal. calcd. (%) for C 43 H 47 N 3 S 2 Se: C, 68.96; H, 6.33; N, 5.61; S, 8.56; Se,10.54. Found: C, 68.69; H, 6.38; N, 5.64; S, 8.64. 3 Results and discussion 3.1 Synthesis and characterization The synthetic routes of monomers and copolymer are outlined in Scheme 1 . 2,7-Dibromocarbazole (4) was synthesized according to the literature [14,17] under PPh 3 -mediated reductive cyclization. Alkylation of (4) with 9-heptadecane-p-toluenesulfonate afforded N-9′-heptadecanyl-2,7-dibromocarbazole (5) [14] . The Y-shaped long alkyl chain in the carbazole unit makes the polymer with high solubility and relative high molecular weight. 2,7-Bis(4′,4′,5′,5′-tetramethyl-1′,3′,2′-dioxaborolan-2′-yl)-N-9″-heptadecanylcarbazole (6) was synthesized through a double lithiation of (5) with LiBu at −78 °C, and subsequent quenching with isopropoxy boronic ester. 4,7-Dibromo-2,1,3-benzothiadiazole (8) was reduced by NaBH 4 , and subsequently oxidated by SeO 2 to give 4,7-dibromo-2,1,3-benzoselenadiazole (10), which was converted to 4,7-bis(2-thienyl)-2,1,3-benzoselenadiazole (11) by Stille coupling reaction with tri-N-butylstannyl-2-thiophene (7) in the presence of PdCl 2 (PPh 3 ) 2 , and subsequently brominated by N-bromosuccinimide (NBS) to give 4,7-bis(5-bromo-2-thienyl)-2,1,3-benzoselenadiazole (12). The alternating copolymer was synthesized via a Suzuki polycondensation of (6) and (12). The weight-average molecular weight ( M w ) and number-average molecular weight ( M n ) are 17,000 and 14,000 respectively, with a polydispersity (PDI) of 1.21. The copolymer is soluble in common organic solvents, such as chloroform, THF and chlorobenzene. The thermogravimetric analysis (TGA) and differential scanning calorimetry (DSC) plots are shown in Fig. 1 and the thermal analytical data are summarized in Table 1 . The polymer reveals excellent thermal stability with a high decomposed temperature (corresponding to 5% weight loss) at 390 °C, while the glass-transition temperature is determined at 140 °C. 3.2 Photophysical properties Fig. 2 shows the UV–vis absorption spectra of PCzDBSe. The polymer presents two absorption bands both in chloroform solution and in thin film, which is in accordance with other D-A copolymers [13,14] . The absorption peak at long wavelength could be attributed to the π–π ∗ transition of the low bandgap units, while the absorption peak at short wavelength is possibly the result of the π–π ∗ transition of carbazole units [15,19] . We note that the absorption peak of the film is red-shifted 16 nm as compared with that in solution, as a result of the intermolecular interaction in solid state [20] . The optical bandgap of the polymer is 1.73 eV, deduced from the absorption onset of the film at 716 nm. The optical properties of PCzDBSe were summarized in Table 2 . The absorption of PCzDBSe has a red-shift of 56 nm compared with that of its BT analogue (PCDTBT) [6,14] . To get an insight into the charge transfer process in the donor–acceptor blend films, the photoluminescence (PL) of blends along with that of the pure polymer has been investigated. As shown in Fig. 3 , the PL of the polymer in film locates in the near-infrared region with a maximum emission at 724 nm, and is thoroughly quenched by the addition of 6,6-phenyl-C 61 -butyric acid methyl ester (PC 61 BM) or 6,6-phenyl-C 71 -butyric acid methyl ester (PC 71 BM), indicating a highly efficient exciton dissociation at the interface between the polymer and PCBM [1] . Therefore efficient PSCs can be constructed based on the PCzDBSe:PCBM blend. 3.3 Electrochemistry As shown in Fig. 4 , the cyclic voltammogram of PCzDBSe presents one oxidation process ( E ox 1 / 2 = 1.03 V ) and one reduction process ( E re 1 / 2 = − 1.17 V ) . Based on the recorded oxidation potential, PCzDBSe should show good air stability [21] . From the onset oxidation potential ( E ox = 0.88 V) and the onset reduction potential ( E re = −0.85 V) of the polymer, the highest occupied molecular orbital (HOMO) and the lowest unoccupied molecular orbital (LUMO) levels were calculated to be −5.28 and −3.55 eV, respectively ( Table 2 ). The HOMO of PCzDBSe is 0.22 eV higher than that of PCDTBT. The corresponding electrochemical bandgap is 1.73 eV, which is similar to the optical bandgap within the experimental error. Given these electrochemical data and the observed PL quenching as shown above in the PCzDBSe:PCBM blend, and taking into account that the LUMO energy of PCBM is −4.3 eV, one can assume that the PCzDBSe can potentially lead to PSCs with PCE over 6% under ideal conditions [22] . 3.4 Field effect transistor performances Top contact OFET of PCzDBSe was fabricated on pre-treated SiO 2 /Si substrates as described in Section 2.3 . Fig. 5 shows the output at different gate voltages and the transfer characteristics for OFET using spin-coating PCzDBSe on OTS-treated SiO 2 /Si substrates. The copolymer was found to exhibit typical p-type organic semiconductor characteristics, and the hole mobility of PCzDBSe was calculated in the saturated regime at V DS = −30 V to be 3.9 × 10 −4 cm 2 V −1 s −1 with a current on/off ratio of 1.4 × 10 2 . The results are consistent with the reported data [11,12] , in which the field effect hole mobility of a series of polycarbazole derivatives on OTS-treated SiO 2 /Si substrates was found to between 2 × 10 −5 cm 2 V −1 s −1 and 1 × 10 −3 cm 2 V −1 s −1 . The high hole mobility of the PCzDBSe is expected to facilitate charge transport and reduce recombination loss in the PSCs; therefore it can lead to an improved device performance. 3.5 Solar cell performances PSCs with a device structure of ITO/PEDOT:PSS/PCzDBSe:PCBM/Al were fabricated following the processes described in Section 2.3 and the performances of a series of devices with different donor/acceptor blending ratios by weight are summarized in Table 3 for comparison. On increasing the weight ratio of polymer:PC 61 BM from 1:1 to 1:4, the PCE increases from 0.39% to 1.46%. This phenomenon is quite common in bulk heterojunction PSCs [23] . A typical J – V characteristic of the devices under AM 1.5G illumination (100 mW cm −2 ) and in the dark is shown in Fig. 6 . A J sc of 4.15 mA cm −2 and a fill factor of 44% are obtained under simulated solar spectra while the V oc of the device is found to be 0.80 V, slightly smaller than that of its BT analogue (PCDTBT, 0.89 V) [14] . The slightly lower V oc in our PCzDBSe devices is probably due to its higher HOMO energy level since it had been suggested that V oc directly correlates with the difference between the LUMO of the acceptor and the HOMO of the donor. When PC 61 BM was replaced by PC 71 BM and used as an electron acceptor in the devices, a significantly improved J sc of 7.23 mA cm −2 ( Fig. 6 ) was recorded, due to its unsymmetrical structure with significantly stronger absorption in the visible region (see Fig. 7 ) [24] . As a result, the overall performance of the device is improved, leading to a PCE of 2.58%. The external quantum efficiency (EQE) plot of the devices under short-circuit conditions is shown in Fig. 8 , in which photoresponse up to 700 nm is clearly displayed. Note that the EQE curve of the devices has two features – a peak around 400 nm and another at 600 nm, closely following the trend observed in the absorption spectra of the PCzDBSe ( Fig. 2 ), indicating that the harvested photons over the entire absorption spectra contribute to the photocurrent. The device exhibits a maximal EQE of 58% at 390 nm and an EQE of 40% at 600 nm. Optimization of PSCs based on PCzDBSe is on the way and it is expected that PCE can be further improved under optimized fabrication conditions (film morphology, thickness of active layer, electrode buffer layer etc.). 4 Conclusion In conclusion, a novel conjugated alternating copolymer (PCzDBSe) based on N-9′-heptadecanyl-2,7-carbazole and 5,5-(4′,7′-di-2-thienyl-2′,1′,3′-benzoselenadiazole) was synthesized by Suzuki polycondensation. Compared with its analogue based on 2,1,3-benzothiadiazole (BT) unit, the absorption onset of the PCzDBSe is red-shifted by 56 nm, extended to 716 nm. The deduced optical bandgap of PCzDBSe is 1.73 eV, which is 0.14 eV narrower than that of PCDTBT. The hole mobility of PCzDBSe as deduced from a solution-processed OFET was found to be 3.9 × 10 −4 cm 2 V −1 s −1 . V oc , J sc and FF of the devices fabricated from the PCzDBSe are 0.75 V, 7.23 mA cm −2 , and 45%, respectively, leading to a power conversion efficiency (PCE) of 2.58%. Acknowledgements The authors are deeply grateful to the National Nature Science Foundation of China (nos. 60906032, 50990065 , and U0634003 ) and the State Key Basic Research Project of China (nos. 2009CB623602 and 2009CB930604 ) for the financial support. References [1] (a) N.S. Sariciftci L. Smilowitz A.J. Heeger F. Wudl Science 258 5087 1992 1474 1476 (b) G. Yu J. Gao J.C. Hummelen F. Wudl A.J. Heeger Science 270 5243 1995 1789 1791 [2] (a) H. Hoppe M. Niggemann C. Winder J. Kraut R. Hiesgen A. Hinsch Adv Funct. Mater. 14 10 2004 1005 1011 (b) S.E. Shaheen C.J. Brabec N.S. Sariciftci F. Padinger T. 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Caretti Polymer 49 23 2008 4942 4948 (c) S.M. Zhang C. He Y. Liu X.W. Zhan J.W. Chen Polymer 50 15 2009 3595 3599 (d) A.P. Zoombelt M.A.M. Leenen M. Fonrodona Y. Nicolas M.M. Wienk R.A.J. Janssen Polymer 50 19 2009 4564 4570 [6] S.H. Park A. Roy S. Beaupre S. Cho N. Coates J.S. Moon Nat. Photonics 3 5 2009 297 303 [7] Y.Y. Liang D.Q. Feng Y. Wu S.T. Tsai G. Li C. Ray J Am Chem Soc 131 22 2009 7792 7799 [8] (a) S. Akoudad J. Roncali Chem Commun 19 1998 2081 2082 (b) Q.T. Zhang J.M. Tour J Am Chem Soc 120 22 1998 5355 5362 [9] S. Wakim N. Blouin E. Gingras Y. Tao M. Leclerc Macromol. Rapid Commun. 28 17 2007 1798 1803 [10] A. Michaud N. Blouin D. Gendron M. Leclerc Polym Prepr (Am Chem Soc Div Polym Chem) 48 2 2007 77 78 [11] N. Blouin A. Michaud D. Gendron S. Wakim E. Blair R. Neagu-Plesu J Am Chem Soc 130 2 2008 732 742 [12] S. Wakim S. Beaupre N. Blouin B.R. Aich S. Rodman R. Gaudiana J Mater Chem 19 30 2009 5351 5358 [13] (a) N. Blouin M. Leclerc Acc Chem Res 41 9 2008 1110 1119 (b) P.-L.T. Boudreault N. Blouin M. Leclerc Adv Polym Sci 212 2008 99 124 (c) N. Leclerc A. Michaud K. Sirois J.-F. Morin M. Leclerc Adv Funct Mater 16 13 2006 1694 1704 (d) Y. Zou D. Gendron R. Badrou-Aich A. Najari Y. Tao M. Leclerc Macromolecules 42 8 2009 2891 2894 (e) J.L. Li F. Dierschke J.S. Wu A.C. Grimsdale K. Mullen J Mater Chem 16 1 2006 96 100 (f) F.C. Krebs J. Alstrup K. Norrman M. Jorgensen Solar Energy Mater Solar Cells 90 17 2006 2777 2792 [14] N. Blouin A. Michaud M. Leclerc Adv. Mater. 19 2007 2295 2300 [15] (a) E.G. Wang M. Wang L. Wang C.H. Duan J. Zhang W.Z. Cai Macromolecules 42 13 2009 4410 4415 (b) P.L.T. Boudreault A. Michaud M. Leclerc Macromol Rapid Commun 28 2007 2176 2179 (c) E.G. Wang L. Wang L.F. Lan C. Luo W.L. Zhuang J.B. Peng Appl Phys Lett 92 3 2008 033307-3 (d) J.P. Lu F.S. Liang N. Drolet J.F. Ding Y. Tao R. Movileanu Chem Commun 42 2008 5315 5317 (e) Z.G. Zhu D. Waller R. Gaudiana J Macromol Sci Part A 44 10–12 2007 1249 1253 (f) C.P. Chen S.H. Chan T.C. Chao C. Ting B.T. Ko J Am Chem Soc 130 38 2008 12828 12833 (g) E.J. Zhou M. Nakamura T. Nishizawa Y. Zhang Q.S. Wei K. Tajima Macromolecules 41 22 2008 8302 8305 (h) J.H. Hou H.Y. Chen S.Q. Zhang G. Li Y. Yang J Am Chem Soc 130 48 2008 16144 16145 (i) W.Y. Wong X.Z. Wang Z. He A.B. Djurisic C.T. Yip K.Y. Cheung Nat Mater 6 7 2007 521 527 [16] J. Hou M.-H. Park S. Zhang Y. Yao L.-M. Chen J.-H. Li Macromolecules 41 16 2008 6012 6018 [17] A.W. Freeman M. Urvoy M.E. Criswell J Org Chem 70 13 2005 5014 5019 [18] (a) J.T. Pinhey E.G. Roche J. Chem. Soc. Perkin Trans. I 8 1988 2415 2421 (b) K. Pilgram M. Zupan R. Skiles J Heterocycl Chem 7 3 1970 629 633 (c) Y. Tsubata T. Suzuki T. Miyashi Y. Yamashita J Org Chem 57 25 1992 6749 6755 [19] (a) E.G. Wang C. Li W.L. Zhuang J.B. Peng Y. Cao J Mater Chem 18 7 2008 797 801 (b) X. Li W. Zeng Y. Zhang Y. Zhang Q. Hou W. Yang Y. Cao Eur Polym J 41 12 2005 2923 2933 (c) J.F. Morin S. Beaupre M. Leclerc I. Levesque M. D'lorio Appl Phys Lett 80 3 2002 341 343 [20] T. Yamamoto D. Komarudin M. Arai B.L. Lee H. Suganuma N. Asakawa J Am Chem Soc 120 9 1998 2047 2058 [21] D.M. deLeeuw M.M.J. Simenon A.R. Brown R.E.F. Einerhand Synth Met 87 1 1997 53 59 [22] M.C. Scharber D. Mühlbacher M. Koppe P. Denk C. Waldauf A.J. Heeger Adv Mater 18 2006 789 794 [23] S. Millefilorini E. Kozma M. Catellani S. Luzzati Thin Solid Films 516 20 2008 7205 7208 [24] M.M. Wienk J.M. Kroon W.J.H. Verhees J. Knol J.C. Hummelen P.A. van Hal Angew Chem Int Ed Engl 42 29 2003 3371 3375",
        "keywords": [
            "2",
            "7-carbazole",
            "alternating copolymer",
            "benzoselenadiazole",
            "weight loss",
            "short circuit current",
            "thermal stability",
            "conversion efficiency",
            "organic field effect transistor",
            "glass transition temperature"
        ],
        "authors": [
            {
                "name": "Wei Zhao",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Laboratory of Specially Functional Materials, Ministry of Education, South China University of Technology, Guangzhou 510640, PR China"
            },
            {
                "name": "Wanzhu Cai",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Laboratory of Specially Functional Materials, Ministry of Education, South China University of Technology, Guangzhou 510640, PR China"
            },
            {
                "name": "Ruixia Xu",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Laboratory of Specially Functional Materials, Ministry of Education, South China University of Technology, Guangzhou 510640, PR China"
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Xiong Gong",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Laboratory of Specially Functional Materials, Ministry of Education, South China University of Technology, Guangzhou 510640, PR China"
            },
            {
                "name": "Hongbin Wu",
                "org": ""
            },
            {
                "name": "Yong Cao",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Laboratory of Specially Functional Materials, Ministry of Education, South China University of Technology, Guangzhou 510640, PR China"
            }
        ],
        "venue": "Polymer",
        "year": 2010
    },
    "HRtflbbZ": {
        "id": "HRtflbbZ",
        "title": "Integration of organic thin-film transistor and polymer light-emitting diodes",
        "abstract": "We investigated the technology and the related physical problems for integrating organic thin-film transistor (OTFT) and polymer light-emitting diode (PLED). The OTFT uses Pentacene as the active medium, Ta 2O 5 as dielectric layer, Ta as gate electrode and Au as source/drain electrodes. The structure of PLED device is ITO/PEDOT: PEO (polyethylene oxide)/P-PPV or MEH-PPV/Ba/Al. The PEDOT: PEO, P-PPV and MEH-PPV film layers were obtained by using screen printing technology. The transistors have a threshold voltage of -7.1 V and carrier mobility of 0.91 cm 2/(V · s). The luminance of the PLEDs with P-PPV and MEH-PPV emissive layer when were driven by OTFT could reach 124 and 22 cd/m 2, and the maximal luminous efficiency are 12.4 and 1.1 cd/A, respectively. © 2010 Chin. Phys. Soc.",
        "keywords": [
            "Integration",
            "Organic thin-film transistor",
            "Polymer light-emitting diode",
            "Screen printing"
        ],
        "authors": [
            {
                "name": "Jianhua Zou",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Linfeng Lan",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "RuiXia Xu",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Wei Yang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Junbiao Peng",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            }
        ],
        "venue": "Wuli Xuebao/Acta Physica Sinica",
        "year": 2010
    },
    "wJ8q11s1": {
        "id": "wJ8q11s1",
        "title": "A novel heteroleptic iridium complex with multifunctional ligands used for polymeric light-emitting diodes",
        "abstract": "Highlights ► The main ligand contains a hole-transporting group, an electron-transporting group and a solubilizing group. ► The ancillary ligand is used for improving yield and stability. ► The iridium complex possesses good solubility, good thermal stability with Δ T 5% of 390 °C and T g of 218 °C. ► PLEDs using the iridium complex show the maximum luminance of 7746 cd cm −2 and maximum current efficiency of 14.0 cd A −1 . Abstract A novel iridium complex using 3-(5-(4-(pyridin-2-yl)phenyl)-1,3,4-oxadiazol-2-yl)-9-hexyl-9H-carbazole containing both hole-transporting group and electron-transporting group as main ligand and 2-(5-p-tolyl-2H-1,2,4-triazol-3-yl)pyridine as ancillary ligand was synthesized and investigated in this paper. The iridium complex possesses high solubility, high thermal stability with 5% weight-reduction temperature (Δ T 5% ) of 390 °C and glass-transition temperature ( T g ) of 218 °C. Polymeric light-emitting diodes (PLEDs) based on structure of ITO/PEDOT: PSS/PVK: PBD: iridium complex/TPBI/CsF/Al fabricated by solution-processed technology were measured. The PLED using the iridium complex as phosphorescent dopant at 4 wt.% doping concentration is optimal which shows the maximum luminance of 7746 cd·cm −2 , maximum current efficiency of 14.0 cd A −1 and maximum external quantum efficiency of 5.8% with CIE coordinates of (0.48, 0.50). The EL emission originates from both monomers and exciplexes formed from the iridium complex and PVK. Keywords Iridium complex Polymeric light-emitting diode Carbazole Oxadiazole 1,2,4-Triazole 1 Introduction Due to potential applications in full-color plat–panel displays, liquid crystal display backlights and solid-state lighting sources, organic light-emitting diodes (OLEDs) are under intense investigation [1–5] . Among all kinds of electroluminescent (EL) materials, organic iridium(III) complexes have attracted considerable interest, because both singlet and triplet excitons can be harvested to generate light with 100% theoretical internal quantum efficiency (IQE) [5–7] . Up to now, vacuum-deposited (mostly based on small molecule materials) and solution-processed (mostly based on polymer materials) are two dominating technologies for fabricating OLEDs. In contrast to vacuum-deposited, solution-processed technology can offer some unique advantages, such as low-cost, easy-processibility over a large surface area by spin-coating, ink-jet printing, or screen-printing, and better controlling of the doping level [8,9] . In the recent years, small-molecule iridium complexes doped polymeric light-emitting diodes (PLEDs) have been developed rapidly, because such EL devices have brought together the advantages of solution-processed technology and high efficiency of small-molecule electrophosphorescent materials [9–14] . In order to be used in PLEDs, small-molecule iridium complexes are required to possess some special properties such as high solubility, high compatibility with polymer host materials, high stability as well as high EL efficiency. Some functional groups have been appended in ligands for improving these properties, for example, long alkyl chains were used for increasing solubility and compatibility with host materials [15–17] , carrier-transporting functional groups such as triphenylamine, carbazole and oxadiazole were used for improving EL performance by increasing carrier-transporting property [7,18–22] . Cyclometalated iridium complexes can be classified into homoleptic and heteroleptic complexes according to the ligands used in the complexes. Although homoleptic iridium complexes exhibit desirable photophysical properties for applications in OLEDs, heteroleptic iridium complexes offer several advantages such as easy preparation, easy tuning of solubility and photophysical properties. Up to now, β-diketonates are the most widely used ancillary ligands in heteroleptic iridium complexes [5] , some other ancillary ligands such as picolate [23–25] , 2-(1H-tetrazol-5-yl)pyridine [24,25] , 2-(2H-1,2,4-triazol-3-yl)pyridine, 2-(1H-pyrazol-5-yl)pyridine and their derivatives [25–27] also have been reported. In comparison with other ancillary ligands, iridium complexes using 2-(2H-1,2,4-triazol-3-yl)pyridine and their derivatives own some advantages, such as being easily synthesized and purified with high yield, easily tuning photophysical properties by changing substitutional groups on triazole ring, high thermal stability and EL efficiency [25–27] . In this paper, 3-(5-(4-(pyridin-2-yl)phenyl)-1,3,4-oxadiazol-2-yl)-9-hexyl-9 H -carbazole was synthesized and used as main ligand in a novel heteroleptic iridium complex (i. e. compound 10 shown in Scheme 1 ) with an ancillary ligand of 2-(5-p-tolyl-2H-1,2,4-triazol-3-yl)pyridine. In this iridium complex, carbazole–oxadiazole unit containing both hole-transporting group and electron-transporting group was expected to be beneficial to improving EL performance, n-hexyl on carbazole group was expected to improve solubility and compatibility with host materials, 2-(5-p-tolyl-2H-1,2,4-triazol-3-yl)pyridine was expected to improve yield and stability. The thermal properties, photophysical properties, electrochemical properties and EL performance of this novel iridium complex were carefully investigated. 2 Experimental 2.1 Synthesis and characterization of iridium(III) complex 2.1.1 General information Chemicals and reagents were purchased from commercial sources and used without further purification unless otherwise stated. 1 H NMR spectra were recorded on a Bruker AV300 spectrometer operating at 300 MHz, tetramethylsilane (TMS) was used as internal standard. Mass spectra (MS) were obtained on a Bruker Esquire HCT PLUS liquid chromatography mass spectrometer (LC–MS) with an electrospray ionization (ESI) interface using acetonitrile as matrix solvent. Elemental analyses (EA) were performed on a Vario EL Elemental Analysis Instrument. Ultraviolet–visible (UV–Vis) absorption spectra were recorded on a HP8453E spectrophotometer. Photoluminescence (PL) spectra were recorded on a Fluorolog–3 spectrophotometer. PL quantum yields were determined in an integrating sphere ISO80 (Labsphere) with 325 nm excitation wavelength of HeCd laser (Mells Griot). Differential scanning calorimetry (DSC) curves were measured on a Netzsch DSC200 analyzer at a heating rate of 10 °C min −1 under N 2 . Thermogravimetry (TG) curves were measured on a Netzsch TG209 thermal analyzer at a heating rate of 20 °C min −1 under N 2 . Cyclic voltammetry (CV) was measured on a computer-controlled CHI800C electrochemical analyser. 2.1.2 Synthesis of 2-(5-p-tolyl-2H-1,2,4-triazol-3-yl)pyridine ( 2 ) (Pyridine-2-yl)amidrazone ( 1 ) was synthesized according to the reported procedure [27] . 4-Methylbenzoic acid (2.72 g, 20 mmol) was added in SOCl 2 (40 mL) and refluxed for 12 h to give 4-methylbenzoyl chloride, excess SOCl 2 was removed by vacuum distillation. After 4-methylbenzoyl chloride was cooled to room temperature, Na 2 CO 3 (1.27 g, 12 mmol) and dried tetrahydrofuran (THF, 20 mL) were added, then an anhydrous saturated solution of compound 1 (2.72 g, 20 mmol) in THF was added dropwise with stirring. After being stirred for 4 h, a pale yellow precipitate was produced and collected on a filter, and then suspended in ice-water with stirring for 30 min. The precipitate was collected by a filter again and dried in vacuum. The dried solid was added in ethylene glycol (30 mL) and refluxed for 1 h. After being cooled to room temperature, a white precipitate was produced and collected on a filter, washed with deionized water. The product was dried under vacuum and used without further purification. Yield 85% (4.02 g), white solid. 1 H NMR (300 MHz, DMSO-D 6 , 25 °C, ppm): δ = 14.77 (s, 1H, –NH–), 8.73 (d, 1H, 3 J = 4.5 Hz, ArH), 8.18 (d, 1H, 3 J = 7.8 Hz, ArH), 7.98–8.05 (m, 3H, ArH), 7.55 (dd, 1H, 3 J = 6.6 Hz, 4 J = 5.1 Hz, ArH), 7.30 (d, 2H, 3 J = 7.8 Hz, ArH), 2.36 (s, 3H, –CH 3 ). Element Anal. Calc. for C 14 H 12 N 4 (%): C, 71.17; H, 5.12; N, 23.71. Found (%): C, 71.52; H, 5.09; N, 23.39. 2.1.3 Synthesis of 9-hexyl-9H-carbazole ( 3 ) After a mixture of KOH (14.0 g, 250 mmol) and carbazole (6.60 g, 40 mmol) in acetone (80 mL) was stirred for 30 min, a solution of 1-bromohexane (9.9 g, 60 mmol) in acetone (20 mL) was added dropwise with stirring. After 10 h, the reaction mixture was poured into water with stirring. The mixture was extracted with CH 2 Cl 2 , the organic phase was washed with water and dried (anhydrous Na 2 SO 4 ). The solvent was distilled off, the residue was chromatographed over silica gel, eluting with petroleum ether (60–90 °C)/CH 3 COOC 2 H 5 (volume ratio, 10:1). Yield 86% (8.53 g), colorless needles. 1 H NMR (300 MHz, CDCl 3 , 25 °C, ppm): δ = 8.13 (d, 2H, 3 J = 7.8 Hz, ArH), 7.41–7.51 (m, 4H, ArH), 7.22–7.27 (m, 2H, ArH), 4.31 (t, 2H, 3 J = 7.2 Hz, –N–CH 2 –), 1.84–1.93 (m, 2H, –N–C–CH 2 –), 1.29–1.56 (m, 6H, –(CH 2 ) 3 –), 0.90 (t, 3H, –CH 3 ). Element Anal. Calc. for C 18 H 21 N (%): C, 86.01; H, 8.42; N, 5.57. Found (%): C, 85.86; H, 8.63; N, 5.51. 2.1.4 Synthesis of 3-formyl-9-hexyl-9H-carbazole ( 4 ) POCl 3 (2 mL) was added dropwise to anhydrous DMF (25 mL) with stirring in an ice bath. Then dried compound 3 (5.02 g, 20 mmol) was added in, the mixture was slowly heated to 80 °C and kept for 6 h. The cooled reaction mixture was slowly poured into fragmentized ice and neutralized with Na 2 CO 3 . The mixture was extracted with CH 2 Cl 2 , the organic phase was washed with water and dried (anhydrous Na 2 SO 4 ). The solvent was distilled off, the residue was chromatographed over silica gel, eluting with petroleum ether (60–90 °C) and CH 2 Cl 2 (volume ratio, 2:1). Yield 78% (4.35 g), brownish-yellow oil. 1 H NMR (300 MHz, CDCl 3 , 25 °C, ppm): δ = 10.07 (s, 1H, –CHO), 8.55 (d, 1H, –ArH), 8.12 (d, 1H, 3 J = 7.8 Hz, –ArH), 7.98 (dd, 1H, 3 J = 8.4 Hz, –ArH), 7.50–7.55 (m, 1H, ArH), 7.34–7.44 (m, 2H, ArH), 7.29–7.31 (t, 1H, ArH), 4.25 (t, 2H, 3 J = 7.2 Hz, –N–CH 2 –), 1.80–1.90 (m, 2H, –N–C–CH 2 –), 1.25–1.39 (m, 6H, –(CH 2 ) 3 –), 0.87 (t, 3H, –CH 3 ). Element Anal. Calc. for C 19 H 21 NO (%):C, 81.68; H, 7.58; N, 5.01. Found (%): C, 81.83; H, 7.69; N, 5.14. 2.1.5 Synthesis of 3-cyano-9-hexyl-9H-carbazole ( 5 ) Ammonia (25∼28%, 50 mL) was added to a solution of compound 4 (5.58 g, 20 mmol) in THF (25 mL), then I 2 (5.58 g, 22 mmol) was added in. After being stirred for 1.5 h, Na 2 S 2 O 3 was added in until the blackish-brown vanished. The reaction mixture was extracted with CH 2 Cl 2 , the organic phase was washed with water and dried (anhydrous Na 2 SO 4 ). The solvent was distilled off, the residue was chromatographed over silica gel, eluting with petroleum ether (60–90 °C) and CH 2 Cl 2 (volume ratio, 3:1). Yield 92% (5.14 g), white solid. 1 H NMR (300 MHz, CDCl 3 , 25 °C, ppm): δ = 8.41 (t, 1H, ArH), 8.13 (dt, 1H, 3 J = 7.8 Hz, ArH), 7.72 (dd, 1H, 3 J = 8.4 Hz, ArH), 7.55–7.57 (m, 1H, ArH), 7.44–7.49 (m, 2H, ArH), 7.28–7.37 (m, 1H, ArH), 4.34 (t, 2H, 3 J = 7.2 Hz, –N–CH 2 –), 1.80–1.90 (m, 2H, –N–C–CH 2 –), 1.29–1.58 (m, 6H, –(CH 2 ) 3 –), 0.88 (t, 3H, –CH 3 ). Element Anal. Calc. for C 19 H 20 N 2 (%): C, 82.57; H, 7.29; N, 10.14. Found: C, 82.41; H, 7.38; N, 10.21. 2.1.6 Synthesis of 3-(1H-tetrazol-5-yl)-9-hexyl-9H-carbazole ( 6 ) Compound 5 (4.14 g, 15 mmol), sodium azide (14.63 g, 225 mmol) and ammonium chloride (12.04 g, 225 mmol) in DMF (150 mL) was heated to 120 °C with mechanical agitation for 72 h. The cooled reaction mixture were poured into ice-water and acidified with HCl to pH ≈ 1.0. A white precipitate was produced and collected on a filter, washed with water and dried in vacuum. Yield 84% (4.00 g), white solid. 1 H NMR (300 MHz, DMSO-D 6 , 25 °C, ppm): δ = 8.86 (s, 1H, ArH), 8.24 (d, 1H, 3 J = 7.8 Hz, ArH), 8.12 (d, 1H, 3 J = 8.7 Hz, ArH), 7.82 (d, 1H, 3 J = 8.7 Hz, ArH), 7.66 (d, 1H, 3 J = 8.1 Hz, ArH), 7.52 (t, 1H, ArH), 7.28 (t, 1H, ArH), 4.44 (t, 2H, 3 J = 6.0 Hz, –N–CH 2 –), 1.71–1.86 (m, 2H, –N–C–CH 2 –), 1.17–1.35 (m, 6H, –(CH 2 ) 3 –), 0.79 (t, 3H, –CH 3 ). Element Anal. Calc. For C 19 H 21 N 5 (%): C, 71.45; H, 6.63; N, 21.93. Found (%): C, 71.28; H, 6.75; N, 21.97. 2.1.7 Synthesis of 3-(5-(4-bromophenyl)-1,3,4-oxadiazol-2-yl)-9-hexyl-9H-carbazole ( 7 ) A saturated anhydrous solution of compound 6 (3.20 g, 10 mmol) in pyridine was added dropwise into another anhydrous solution of 4-bromobenzoyl chloride (2.20 g, 10 mmol) in pyridine (30 mL) with stirring, then the reaction mixture was refluxed under argon for 48 h. The cooled reaction mixture was poured into water, a white precipitate was produced and collected on a filter, washed with water and dried in vacuum. The crude product was purified by silica gel column chromatography with CH 2 Cl 2 as eluent. Yield 82% (3.90 g), white solid. 1 H NMR (300 MHz, CDCl 3 , 25 °C, ppm): δ = 8.85 (d, 1H, 3 J = 1.2 Hz, ArH), 8.19–8.26 (m, 2H, ArH), 8.04–8.09 (m, 2H, ArH), 7.68–7.72 (m, 2H, ArH), 7.44–7.58 (m, 3H, ArH), 7.29–7.35 (m, 1H, ArH), 4.35 (t, 2H, 3 J = 7.2 Hz, –N–CH 2 –), 1.86–1.95 (m, 2H, –N–C–CH 2 –), 1.28–1.41 (m, 6H, –(CH 2 ) 3 –), 0.87 (t, 3H, 3 J = 7.2 Hz, –CH 3 ). Element Anal. Calc. For C 26 H 24 BrN 3 O (%): C, 65.83; H, 5.10; N, 8.86. Found (%): C, 65.57; H, 5.15; N, 8.95. 2.1.8 Synthesis of 3-(5-(4-(pyridin-2-yl)phenyl)-1,3,4-oxadiazol-2-yl)-9-hexyl-9H-carbazole ( 8 ) Compound 7 (2.37 g, 5 mmol), 2-(tri- n -butylstannyl)pyridine [28] (2.21 g, 6 mmol) and Pd(PPh 3 ) 4 (0.23 g, 0.2 mmol) in toluene (40 mL) were refluxed under argon for 48 h. After being cooled to room temperature, the solvent was removed, the residue was chromatographed over silica gel, eluting with CH 2 Cl 2 and CH 3 COOC 2 H 5 (volume ratio, 5: 1). Yield 55% (1.30 g), white solid. 1 H NMR (300 MHz, CDCl 3 , 25 °C, ppm): δ = 8.90 (s, 1H, ArH), 8.77–8.79 (q, 1H, ArH), 8.21–8.33 (m, 6H, ArH), 7.83 (t, 2H, ArH), 7.46–7.58 (m, 3H, ArH), 7.28–7.36 (m, 2H, ArH), 4.37 (t, 2H, 3 J = 6.6 Hz, –N–CH 2 –), 1.85–1.95 (m, 2H, –N–C–CH 2 –), 1.28–1.44 (m, 6H, –(CH 2 ) 3 –), 0.90 (t, 3H, –CH 3 ). MS (ESI, m/z): 473.3 [M + H] + . Element Anal. Calc. for C 31 H 28 N 4 O (%): C, 78.79; H, 5.97; N, 11.86. Found (%): C, 78.67; H, 6.08; N, 11.93. 2.1.9 Synthesis of the iridium(III) complex ( 10 ) IrCl 3 ·3H 2 O (0.42 g, 1.2 mmol), compound 8 (1.28 g, 2.7 mmol) in H 2 O (8 mL) and 2-methoxyethanol (24 mL) were refluxed under argon for 24 h. After being cooled to room temperature, a yellow precipitate was produced and collected on a filter, washed with water and methanol alternately. The chloro-bridged dimer ( 9 ) was obtained after being dried in vacuum and was directly used for the next step without characterization and further purification. Yield 76% (1.21 g), yellow solid. The chloro-bridged dimer ( 9 ) (0.47 g, 0.2 mmol), compound 2 (0.19 g, 0.8 mmol) and K 2 CO 3 (0.55 g, 4 mmol) in 2-ethoxyethanol (20 ml) was refluxed under argon for 24 h. The cooled reaction mixture was poured in water. A yellow precipitate was produced and collected on a filter, washed by water and methanol alternately. The crude product was purified by silica gel column chromatography with petroleum ether (60–90 °C)/CH 2 Cl 2 /CH 3 COOC 2 H 5 (volume ratio, 2: 6: 1) as eluent. Yield 65% (0.36 g), yellow solid. 1 H NMR (300 MHz, CDCl 3 , 25 °C, ppm): δ = 8.48–8.82 (m, 2H, ArH), 8.22–8.45 (m, 1H, ArH), 7.88–8.18 (m, 9H, ArH), 7.52–7.88 (m, 9H, ArH), 7.35–7.50 (m, 4H, ArH), 7.20–7.35 (m, 4H, ArH), 6.82–7.15 (m, 7H, ArH), 4.16–4.35 (m, 4H, –N–CH 2 –), 2.30 (s, 3H, Ph–CH 3 ), 1.72–1.98 (m, 4H, –N–C–CH 2 –), 0.95–1.43 (m, 12H, –(CH 2 ) 3 –), 0.83 (t, 6H, –CH 3 ). MS (ESI, m/z): 1371.8 [M + H] + . Element Anal. Calc. for C 76 H 65 IrN 12 O 2 (%): C, 66.60; H, 4.78; N, 12.26. Found (%): C, 66.25; H, 4.96; N, 12.38. 2.1.10 Fabrication and measurements of EL devices Indium–tin oxide (ITO) coated glass with a sheet resistance of 15–20 Ω/□ was used as substrate and anode, cleaned with deionized water, acetone and isopropanol in an ultrasonic bath, then was cleaned by oxygen plasma for 4 min. Then the devices were fabricated on it layer by layer. Structure of the devices: ITO/PEDOT: PSS (40 nm)/emitting layer (70 nm)/TPBI (30 nm)/CsF (1.5 nm)/Al (120 nm), emitting layer: PVK (70%): PBD (30%): iridium complex (2%, 4%, or 6%). Anode buffer layer poly(3,4-ethylenedioxythiophene) doped with poly(styrene sulfonate) (PEDOT: PSS) and emitting layer were fabricated by spin-coating from solution, and were baked in vacuum at 80 °C for 8 h and 25 min respectively. The emitting layers consist of host materials poly(N-vinylcarbazole) (PVK), electron-transporting materials 2-(4-biphenylyl)-5-(4- tert -butylphenyl)-1,3,4-oxadiazole (PBD) and iridium complex at different concentrations, before spin-coating, solutions of them in chlorobenzene at 15 mg mL −1 were prepared according to the mass ratio of PVK: PBD: iridium complex in EL devices. Hole-blocking/electron-transporting layer of 1,3,5-tris(N-phenylbenzimidazol-2-yl)-benzene (TPBI), electron injection layer of CsF and aluminum cathode layer were thermally evaporated with a base pressure of 3 × 10 −4 Pa. The spin-coated film thickness was measured by an Alfa Step 500 surface profilometer (Tencor), layer thickness during thermal deposition was monitored by a quartz crystal thickness/ratio monitor (Model: STM-100/MF, Sycon). The area of every device is 0.19 cm 2 . Current density–luminance–voltage ( I – L – V ) characteristics were measured by a Keithley 236 source measurement unit and a calibrated silicon photodiode. EL spectra and CIE coordinate were recorded by a spectrophotometer (SpectraScan PR-705, Photo Research). 3 Results and discussion 3.1 UV–Vis absorption and PL properties UV–Vis absorption and PL spectra of the iridium complex are shown in Fig. 1 . In UV–vis absorption spectrum of the iridium complex in solution, the strong absorption bands at 200–410 nm can be assigned to the spin-allowed 1 π – π * transition of the ligands. The weak absorption bands at 410–475 nm can be assigned to an admixture of 1 MLCT (metal–ligand charge transfer), 3 MLCT and 3 π – π * states [29,30] . The admixture of 3 MLCT and 3 π – π * with higher-lying 1 MLCT is due to the strong spin–orbit coupling induced by the iridium heavy atom [29,30] . UV–Vis absorption spectrum of pure iridium complex film is very similar to that of iridium complex in solution, however, UV–Vis absorbtion spectrum of iridium complex doped in PVK film is different from them, because the former two absorption spectra both originate from iridium complex, and the latter mainly originates from PVK due to low doping concentration of iridium complex. PL spectra of the iridium complex in solution and doped in PVK film are very similar each other, every of them has a main peak with the maximum emission at 533 nm and 541 nm respectively and a shoulder peak with the maximum emission both at 576 nm. Both of them originate from the iridium complex monomers due to low concentration in solution and PVK film. However, PL spectrum of pure iridium complex film is different. This spectrum is broader and red-shifted relative to PL spectra of the iridium complex in solution and PVK film. Besides a main peak with the maximum emission at 617 nm, two shoulder peaks with the maximum emission at 562 nm and 670 nm also are observed. PL spectrum of pure iridium complex film should originate from the emission of excimers due to face to face π – π interactions between aromatic molecules in the solid state [31] . 3.2 Thermal properties TG and DSC curves of the iridium complex are shown in Fig. 2 . The TG curve shows the iridium complex has a 5% weight-reduction temperature (Δ T 5% ) of 390 °C which implies the iridium complex is difficult to thermally decompose. The DSC curves of twice heating show no crystallization and melting peak but only a glass-transition at 218 °C on its second heating curve which suggests the iridium complex is amorphous with a very high glass-transition temperature ( T g ). The amorphousness and high T g of the light-emitting materials are resistant to crystallization and phase disengagement, and are desirable for EL devices with high stability and efficiency [15,30,32] . The results suggest that the n-hexyl on the carbazole group play a significant role in improving amorphous nature and T g value as well as solubility (the iridium complex is soluble in most common solvents such as CH 2 Cl 2 , CHCl 3 , toluene, chlorobenzene, and acetonitrile) [15,16] . 3.3 Electrochemical properties and HOMO–LUMO energy levels Cyclic voltammetry (CV) was used to investigate electrochemical behavior and HOMO–LUMO energy levels of the iridium complex [11,29,30] . Anhydrous and Ar-saturated CH 2 Cl 2 solution of the iridium complex containing 0.1 mol L −1 tetra-n-butylammonium hexafluorophosphate (TBAPF 6 ) as supporting electrolyte was scanned at 50 mV s −1 . A glass carbon electrode was used as working electrode, a Ag/AgCl electrode was used as reference electrode, a platinum wire was used as counter electrode. Ferrocene (4.8 eV under vacuum) was used as the internal standard material. The cyclic voltammogram of the iridium complex was shown in Fig. 3 . The complex exhibits a one-electron reversible oxidation couple at relatively low positive potential and a quasi-reversible oxidation couple at relatively high positive potential. The former is attributed to metal-centered Ir III /Ir IV oxidation couple [11,16] , the latter maybe originate from the electron-donating carbazole unit [16] . The value of the energy gap ( E g ) of the iridium complex was obtained from the spectroscopy absorption edge of the iridium complex in dilute solution ( E g = 1240/ λ a,edge ) [11] , together with the oxidation potential, the HOMO and LUMO energy levels can be estimated, the results are listed in Table 1 . The HOMO and LUMO levels of the iridium complex are -5.62 eV and -3.01 eV, and lie between the HOMO (−5.80 eV) and LUMO (−2.2 eV) levels of PVK which suggests PVK is suitable host materials for it. 3.4 EL properties EL spectra of the devices using the iridium complex as electroluminescent phosphor at different doping concentrations and PL spectrum of the iridium complex doped in PVK at 4 wt.% are shown in Fig. 4 , and the performance of the devices was listed in Table 2 . A weak emission peak at 380–480 nm can be observed in the EL spectrum at 2 wt.% doping concentration, however, such emission peak has not emerged at 4 wt.% and 6 wt.%. This peak should originate from the PVK–PBD exciplex [33] , because the low doping concentration is not enough to consume the excitons of the PVK. By comparison with PL spectrum of the iridium complex doped in PVK at 4 wt.%, EL spectra become much wider and a new shoulder peak at right around 614 nm is observed, this disparity possibly is caused by the emission of exciplexes formed from the iridium complex and PVK [34,35] . The quantity of the exciplexes increases with increasing doping concentrations [34] , so the emission of this new shoulder peak also strengthens with increasing doping concentrations. The whole EL spectra originate from the emission of both monomers and exciplexes. The CIE coordinates change from (0.46, 0.49) to (0.48, 0.50), and then to (0.49, 0.49) with increasing doping concentrations, all of them lie yellow light region. The turn-on voltages ( V turn-on ) of the devices are 7.0 or 7.3 V, the relatively high driving voltages may be due to the large hole barrier at PEDOT: PSS/PVK interface (HOMOs of PVK ∼ 5.80 eV vs. PEDOT ∼ 5.20 eV) and thick emissive layer (70 nm) [11] . By comparing the performance of the devices at different doping concentrations, we can find 4 wt.% is an optimal doping concentration, for the maximum luminance and efficiency. Luminance and current density vs. voltage, current efficiency (CE) and external quantum efficiency (EQE) vs. current density characteristics of the device at 4 wt.% doping concentration are shown in Fig. 5 . The luminance and current density increase quickly with increasing voltage after turn-on voltage which shows the characteristic feature of the OLEDs, the maximum luminance and current density are 7746 cd·cm −2 (at 17.85 V) and 139 mA·cm −2 (at 18.55 V) respectively. The maximum CE and EQE are 14.0 cd A −1 and 5.8%, the PL efficiency of the iridium complex doped in PVK at 4 wt.% measured by us is 24.8%. Obviously, the EL efficiency is rather lower than PL efficiency, which is common with most phosphorescent OLEDs. The lower EL efficiency relative to PL efficiency mainly caused by field-induced quenching effects and triplet–triplet annihilation [36] , the large hole barrier at PEDOT: PSS/PVK interface maybe also has affected the EL efficiency. The CE and EQE decline slowly with increasing current density nearly linear, the CE remains upon 7.5 cd A −1 at high current density near 100 mA·cm −2 , so do the EQE, these results indicate that the device owns high stability. 4 Conclusions The iridium complex using multifunctional ligands possesses high solubility, high thermal stability with Δ T 5% of 390 °C and T g of 218 °C. Polymeric light-emitting diode using the iridium complex as phosphorescent dopant at 4 wt.% doping concentration shows the maximum luminance of 7746 cd·cm −2 , maximum current efficiency of 14.0 cd A −1 and maximum external quantum efficiency of 5.8% with CIE coordinates of (0.48, 0.50). The EL emission originates from both monomers and exciplexes formed from the iridium complex and PVK. Acknowledgements This work was supported by China Postdoctoral Science Foundation (No. 20090450858), the National Natural Science Foundation of China (No. U0634003) and State Key Basical Research Project of China (No. 2009CB623600). References [1] C.W. Tang S.A. VanSlyke Appl. Phys. Lett. 51 1987 913 [2] J.H. Burroughes D.D.C. Bradley A.R. Brown R.N. Marks K. Mackay R.H. Friend P.L. Burns A.B. Holmes Nature 347 1990 539 [3] B.W. D’Andrade S.R. Forrest Adv. Mater. 16 2004 1585 [4] E. Holder B.M.W. Langeveld U.S. Schubert Adv. Mater. 17 2005 1109 [5] W.-Y. Wong C.-L. Ho Coord. Chem. Rev. 253 2009 1709 [6] M.A. Baldo D.F. O’Brien Y. You A. Shoustikov S. Sibley M.E. Thompson S.R. Forrest Nature 395 1998 151 [7] S. Lamansky P. Djurovich D. Murphy F. Abdel-Razzaq H.-E. Lee C. Adachi P.E. Burrows S.R. Forrest M.E. Thompson J. Am. Chem. Soc. 123 2001 4304 [8] A.C. Grimsdale K.L. Chan R.E. 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        "keywords": [
            "1",
            "2",
            "4-triazole",
            "carbazole",
            "iridium complex",
            "oxadiazole",
            "polymeric light-emitting diode",
            "electron transport",
            "external quantum efficiency",
            "thermal stability",
            "light emitting diode",
            "weight reduction",
            "glass transition temperature"
        ],
        "authors": [
            {
                "name": "Huaijun Tang",
                "org": ""
            },
            {
                "name": "Yanhu Li",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Lab of Specially Functional Materials of the Ministry of Education, South China University of Technology, Guangzhou 510640, PR China"
            },
            {
                "name": "Bing Chen",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Lab of Specially Functional Materials of the Ministry of Education, South China University of Technology, Guangzhou 510640, PR China"
            },
            {
                "name": "Hongbin Wu",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Lab of Specially Functional Materials of the Ministry of Education, South China University of Technology, Guangzhou 510640, PR China"
            },
            {
                "name": "Wei Yang",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Lab of Specially Functional Materials of the Ministry of Education, South China University of Technology, Guangzhou 510640, PR China"
            },
            {
                "name": "Yong Cao",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Lab of Specially Functional Materials of the Ministry of Education, South China University of Technology, Guangzhou 510640, PR China"
            }
        ],
        "venue": "Optical Materials",
        "year": 2011
    },
    "HveBkFVo": {
        "id": "HveBkFVo",
        "title": "Highly efficient polymer phosphorescent light-emitting devices based on a new polyfluorene derivative as host",
        "abstract": "Several highly efficient iridium-complex polymer light-emitting devices (PLEDs) are fabricated,with a newly synthesized blue conjugated polymer,poly[(9,9-bis(4-(2-ethylhexyloxy)phenyl)-fluorene)-co-(3,7-dibenziothiene-S,S-dioxide15)] (PPF-3,7SO15),chosen as host.High luminous efficiencies of 7.4 cd·A 1 and 27.4 cd·A 1 are achieved in red and green PLEDs,respectively,by optimizing the doping concentrations of red phosphorescent dye iridium bis(1-phenylisoquinoline) (acetylacetonate) (Ir(piq)) and green phosphorescent dye iridium tris(2-(4-tolyl)pyridinato-N,C 2) (Ir(mppy) 3).Furthermore,highly efficient white PLEDs (WPLEDs) with the Commission Internationale de l'Eclairage (CIE) coordinates of (0.35,0.38) are successfully produced by carefully controlling the doping concentration of the irid-ium complex.The obtained WPLEDs show maximal efficiencies of 14.4 cd·A 1 and 10.1 lm·W 1,which are comparable to those of incandescent bulbs.Moreover,the electroluminescent spectrum of the white device with an initial luminance of about 1000 cd·m 2 is stable,subject to constant applied current stress,indicating that good device stability can be obtained in this system.",
        "keywords": [
            "host",
            "phosphorescent",
            "polymer light-emitting devices",
            "white"
        ],
        "authors": [
            {
                "name": "BaoZheng Wang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Jie Liu",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Hongbin Wu",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Bin Zhang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Shangsheng Wen",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Wei Yang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            }
        ],
        "venue": "中国物理B",
        "year": 2011
    },
    "oSF3i1AC": {
        "id": "oSF3i1AC",
        "title": "Novel yellow phosphorescent iridium complexes containing a carbazole–oxadiazole unit used in polymeric light-emitting diodes",
        "abstract": "Highlights ► Ir(PPOHC) 3 contains a bipolar carbazole–oxadiazole unit. ► The yellow PLED showed a luminance efficiency of 16.4 cd/A. ► The white PLED showed a luminance efficiency of 15.3 cd/A with CIE of (0.39, 0.44).",
        "keywords": [
            "polymeric light-emitting diode",
            "carbazole",
            "white-light",
            "electroluminescence",
            "iridium complex",
            "oxadiazole",
            "glass transition temperature",
            "weight reduction",
            "external quantum efficiency",
            "thermal stability",
            "light emitting diode"
        ],
        "authors": [
            {
                "name": "Huaijun Tang",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Lab of Specially Functional Materials of the Ministry of Education, South China University of Technology, Guangzhou 510640, PR China"
            },
            {
                "name": "Yanhu Li",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Lab of Specially Functional Materials of the Ministry of Education, South China University of Technology, Guangzhou 510640, PR China"
            },
            {
                "name": "Caihong Wei",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Lab of Specially Functional Materials of the Ministry of Education, South China University of Technology, Guangzhou 510640, PR China"
            },
            {
                "name": "Bing Chen",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Lab of Specially Functional Materials of the Ministry of Education, South China University of Technology, Guangzhou 510640, PR China"
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Hongbin Wu",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Lab of Specially Functional Materials of the Ministry of Education, South China University of Technology, Guangzhou 510640, PR China"
            },
            {
                "name": "Yong Cao",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, Key Lab of Specially Functional Materials of the Ministry of Education, South China University of Technology, Guangzhou 510640, PR China"
            }
        ],
        "venue": "Dyes and Pigments",
        "year": 2011
    },
    "v0O7Pfn8": {
        "id": "v0O7Pfn8",
        "title": "Highly efficient pure white polymer light-emitting devices based on poly(<Emphasis Type=\"Italic\">N</Emphasis>-vinylcarbazole) doped with blue and red phosphorescent dyes",
        "abstract": "Efficient white-polymer-light-emitting devices (WPLEDs) have been fabricated with a single emitting layer containing a hole-transporting\n host polymer, poly(N-vinylcarbzole), and an electron-transporting auxiliary, 1,3-bis[(4-tert-butylphenyl)-1,3,4-oxadiazolyl]-phenylene, codoped with two phosphorescent dyes: Iridium(III)bis (2-(4,6-difluorophenyl)-pyridinato-N,C2′)\n picolinate (FIrpic) and home-made Ir-G2 for blue and red emission, respectively. With the structure of ITO/PEDOT:PSS 4083(40\n nm)/emission layer(80 nm)/Ba(4 nm)/Al(120 nm), the device showed a maximal luminous efficiency (LE) of 13.5 cd A−1(corresponding to an external quantum efficiency (EQE) of 6.8%), and a peak power efficiency (PE) of 6.5 lm W−1 at 6.0 V. Meanwhile, the device exhibited pure white emission with Commission Internationale de l’Eclairage (CIE) coordinates\n of (0.34, 0.35) at a current density of 12 mA cm−2, which is very close to the equi-energy white point with CIE coordinates of (0.33, 0.33). The device performance can be further\n optimized when more balanced hole/electron injection is achieved by incorporating a lower conducting type anode buffer layer\n (PEDOT:PSS) and incorporating poly[(9,9-bis(3′-(N,N-dimethylamino) propyl)-2,7-fluorenene)-alt-2,7-(9,9-dioctyfluorene)] (PFN) as an electron injection layer at the cathode. The optimized device showed an LE of 24.6\n cd A−1 (with an EQE of 14.1%), while the peak power efficiency reached 12.66 lm W−1. Moreover, the WPLEDs showed good electroluminescence (EL) stability over a wide range of operating current density and luminance.",
        "keywords": [
            "white polymer light-emitting device",
            " phosphorescent iridium complex",
            " anode buffer layer",
            " water-/alcohol-soluble conjugated polymer"
        ],
        "authors": [
            {
                "name": "SuJun Hu",
                "org": "Key Laboratory of Specially Functional Materials, Ministry of Education; Institute of Polymer Optoelectronic Materials and Devices,South China University of Technology,Guangzhou,China"
            },
            {
                "name": "JianHua Zou",
                "org": "Key Laboratory of Specially Functional Materials, Ministry of Education; Institute of Polymer Optoelectronic Materials and Devices,South China University of Technology,Guangzhou,China"
            },
            {
                "name": "GuiJiang Zhou",
                "org": "Department of Chemistry and Centre for Advanced Luminescence Materials,Hong Kong Baptist University,Kowloon Tong, Hong Kong,China"
            },
            {
                "name": "DongYun Li",
                "org": "Key Laboratory of Specially Functional Materials, Ministry of Education; Institute of Polymer Optoelectronic Materials and Devices,South China University of Technology,Guangzhou,China"
            },
            {
                "name": "HongBin Wu",
                "org": "Key Laboratory of Specially Functional Materials, Ministry of Education; Institute of Polymer Optoelectronic Materials and Devices,South China University of Technology,Guangzhou,China"
            },
            {
                "name": "ShiJian Su",
                "org": "Key Laboratory of Specially Functional Materials, Ministry of Education; Institute of Polymer Optoelectronic Materials and Devices,South China University of Technology,Guangzhou,China"
            },
            {
                "name": "Wai-Yeung Wong",
                "org": "Department of Chemistry and Centre for Advanced Luminescence Materials,Hong Kong Baptist University,Kowloon Tong, Hong Kong,China"
            },
            {
                "name": "Wei Yang",
                "org": "Key Laboratory of Specially Functional Materials, Ministry of Education; Institute of Polymer Optoelectronic Materials and Devices,South China University of Technology,Guangzhou,China"
            },
            {
                "name": "JunBiao Peng",
                "org": "Key Laboratory of Specially Functional Materials, Ministry of Education; Institute of Polymer Optoelectronic Materials and Devices,South China University of Technology,Guangzhou,China"
            },
            {
                "name": "Yong Cao",
                "org": "Key Laboratory of Specially Functional Materials, Ministry of Education; Institute of Polymer Optoelectronic Materials and Devices,South China University of Technology,Guangzhou,China"
            }
        ],
        "venue": "中国科学:化学(英文版)",
        "year": 2011
    },
    "pkLWk25e": {
        "id": "pkLWk25e",
        "title": "Dual-functional conjugated polymers based on trifluoren-2-yl-amine for RGB organic light-emitting diodes",
        "abstract": "A series of blue-light-emitting conjugated polymers that possess high-lying HOMO energy levels were synthesized by introducing trifluoren-2-yl-amine (TFA) as a building block. The emission color could be effectively tuned in the region of deep-blue and light-blue by introducing various substituents onto the TFA as the pendants. Deep-blue light emission was achieved for the device based on P4FNCz as an emitting layer without using any hole-transport layer (HTL), giving a maximum current efficiency (CE) of 2.44 cd A -1, corresponding to an external quantum efficiency of 3.00%, with Commission Internationale de L'Eclairage (CIE) coordinates of (0.16, 0.12). Thanks to the improved hole injection and transport ability, red- and green-light-emitting devices based on P4FNCz as an HTL were also successfully fabricated, giving a maximum CE of 7 and 25 cd A -1 with CIE coordinates of (0.64, 0.34) and (0.29, 0.64), respectively, which are comparable to those of the devices based on a general HTL of 4,4′-bis(N-(1-naphthyl)-N-phenylamino)biphenyl (NPB). The CIE coordinates of the RGB devices are very close to those of the National Television System Committee (NTSC) and High Definition Television (HDTV) standard colors. The RGB devices achieved by tuning the carrier recombination zone with different electron-transport layers will facilitate the development of the polymer-based full-color flat-panel displays in an alternative process. © 2011 The Royal Society of Chemistry.",
        "keywords": [],
        "authors": [
            {
                "name": "Hua Ye",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Baofeng Zhao",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Ming Liu",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Xiao Zhou",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Yanhu Li",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Dongyun Li",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Shijian Su",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Wei Yang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Yong Cao",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            }
        ],
        "venue": "Journal of Materials Chemistry",
        "year": 2011
    },
    "Ji5qKp1Z": {
        "id": "Ji5qKp1Z",
        "title": "Highly efficient green-emitting electrophosphorescent hyperbranched polymers using a bipolar carbazole-3,6-diyl-co-2,8-octyldibenzothiophene-S,S-dioxide-3,7-diyl unit as the branch",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "jie liu",
                "org": "south china university of technology"
            },
            {
                "name": "lei yu",
                "org": "south china university of technology"
            },
            {
                "name": "chengmei zhong",
                "org": "south china university of technology"
            },
            {
                "name": "ruifeng he",
                "org": "south china university of technology"
            },
            {
                "name": "wei yang",
                "org": "south china university of technology"
            },
            {
                "name": "hongbin wu",
                "org": "south china university of technology"
            },
            {
                "name": "yong cao",
                "org": "south china university of technology"
            }
        ],
        "venue": "",
        "year": 2011
    },
    "MmRjIMWP": {
        "id": "MmRjIMWP",
        "title": "Efficient sky-blue and blue-green light-emitting electrochemical cells based on cationic iridium complexes using 1,2,4-triazole-pyridine as the ancillary ligand with cyanogen group in alkyl chain",
        "abstract": "Sky-blue and blue-green light-emitting cationic iridium (III) complexes with triazole-pyridine as the ancillary ligand, with formula [Ir(dfppy) 2 (trzpy-cn)](PF 6 ) ( C1 ), [Ir(mppy) 2 (trzpy-cn)](PF 6 ) ( C2 ), [Ir(dfppy) 2 (trzpy-hx)](PF 6 ) ( C3 ) and [Ir(mppy) 2 (trzpy-hx)](PF 6 ) ( C4 ) were synthesized, where mppy, trzpy-cn, trzpy-hx are 2-methylphenylpyridine, 2,2-dimethyl-6-(3-methyl-5-(pyridin-2-yl)-4H-1,2,4-triazol-4-yl)hexanenitrile, and 2-(5-methyl-4-octyl-4H-1,2,4-triazol-3-yl)pyridine, respectively. C1/C3 and C2/C4 emit sky-blue and blue-green light peaked at 458 and 484 nm, respectively. Single layer light-emitting electrochemical cells (LECs) based on C1 and C2 show luminous efficiencies (LE) of 2.6 and 6.8 cd/A (corresponding to an external quantum efficiency (EQE) of 2.7 and 2.8%), with CIE coordinates of (0.21, 0.33) and (0.31, 0.53), respectively. As compared with the devices from C3 and C4 , the device efficiencies based on C1 and C 2 are found to be significantly enhanced by 10 times and 4 times, respectively, owing to the incorporation of cyanogen group in the alkyl chain. The results demonstrate that using the triazole-pyridine as ancillary ligand with a cyanogen group in the side alkyl chain are effective strategies to tune the emission into blue region and to improve the efficiency of the cationic iridium complex. Keywords Cationic iridium complex Triazole-pyridine ancillary ligand Sky-blue emission Light-emitting electrochemical cell",
        "keywords": [
            "cationic iridium complex",
            "light-emitting electrochemical cell",
            "sky-blue emission",
            "triazole-pyridine ancillary ligand",
            "light emitting electrochemical cell",
            "external quantum efficiency"
        ],
        "authors": [
            {
                "name": "Bing Chen",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology, Key Laboratory of Special Functional Materials, Ministry of Education, Guangzhou 510640, PR China"
            },
            {
                "name": "Yanhu Li",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology, Key Laboratory of Special Functional Materials, Ministry of Education, Guangzhou 510640, PR China"
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Wen Luo",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology, Key Laboratory of Special Functional Materials, Ministry of Education, Guangzhou 510640, PR China"
            },
            {
                "name": "Hongbin Wu",
                "org": ""
            }
        ],
        "venue": "Organic Electronics",
        "year": 2011
    },
    "yDgVciFX": {
        "id": "yDgVciFX",
        "title": "Red light-emitting hyperbranched fluorene-alt-carbazole copolymers with an iridium complex as the core",
        "abstract": "Red light-emitting hyperbranched copolymers with an iridium complex as the core and fluorene-alt-carbazole as the branches were synthesized by one-pot Suzuki polycondensation. Efficient energy transfer from the poly(3,6-carbazole- alt-2,7-fluorene) segment to the iridium complex occurs when the Ir complex content is as low as 1 mol% in the copolymer. A maximal external quantum efficiency of 6.1% ph/el and a luminous efficiency of 4.7 cd A -1 were obtained with a CIE coordinate of (0.63, 0.32) for the device made from PFCzPh20NapyIr2 copolymer. The efficiency loss upon the increase of current density is significantly reduced since the highly branched structure could suppress the interchain interaction of polymers and the self quenching of the Ir complex. The integration of a phosphorescent complex into hyperbranched polymers can provide a successful molecular design route for solution-processable polymers for PLED applications. © 2011 The Royal Society of Chemistry.",
        "keywords": [],
        "authors": [
            {
                "name": "Ting Guo",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Rong Guan",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Jianhua Zou",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Jie Liu",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Lei Ying",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Wei Yang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Hongbin Wu",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Yong Cao",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            }
        ],
        "venue": "Polymer Chemistry",
        "year": 2011
    },
    "xEXeOm6B": {
        "id": "xEXeOm6B",
        "title": "White light-emitting polymers and devices",
        "abstract": "null",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Bin Zhang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Wei Yang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Hongbin Wu",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            }
        ],
        "venue": "RSC Polymer Chemistry Series",
        "year": 2012
    },
    "GVWECcWg": {
        "id": "GVWECcWg",
        "title": "Bipolar blue-emitting poly(N-9′-heptadecanyl-carbazole-2,7-diyl-co- dibenzothiophene-S,S-dioxide-3,7-diyl)s",
        "abstract": "Poly(N-9′-heptadecanyl-carbazole-2,7-diyl-co-dibenzothiophene-S, S-dioxide-3,7-diyl)s (PCz-SOs) were synthesized by Suzuki polycondensation. The glass transition temperatures (T g) of the polymers increase gradually with the increase of SO unit content, and reach 119 °C for PCz-SO20. The highest occupied molecular orbital (HOMO) and the lowest unoccupied molecular orbital (LUMO) levels reduce gradually with increasing the content of SO unit in the polymers. Devices based on the polymers exhibit an excellent electroluminescent (EL) spectral stability with the variation of applied current densities in a large range of 12-360 mA cm -2. A peak luminous efficiency (LE max) of 4.8 cd A -1 (corresponding to a maximum external quantum efficiency (EQE max) of 3.6%) with 14933 cd m -2 was obtained, and remained at 4.4 cd A -1 even at an applied current density of 100 mA cm -2 based on PCz-SO20 with a single-layer device of ITO/PEDOT:PSS/polymer/CsF/Al. The efficiencies were 12 times that of PCz, resulting from the balanced charge transportation in bipolar polymer PCz-SO20. © 2012 The Royal Society of Chemistry.",
        "keywords": [],
        "authors": [
            {
                "name": "Ruifeng He",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Sujun Hu",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Jie Liu",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Lei Yu",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Bin Zhang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Na Li",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Wei Yang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Hongbin Wu",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Junbiao Peng",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            }
        ],
        "venue": "Journal of Materials Chemistry",
        "year": 2012
    },
    "cGHXB5KO": {
        "id": "cGHXB5KO",
        "title": "Two novel orange cationic iridium(III) complexes with multifunctional ancillary ligands used for polymer light-emitting diodes",
        "abstract": "Two novel orange cationic iridium complexes [(npy)2Ir(o-phen)] PF6 and [(npy)2Ir(c-phen)]PF6 were synthesized. Hnpy: 2-(naphthalen-1-yl)pyridine; o-phen: a 1,10-phenanthroline derivative containing an electron-transporting functional group of 2,5-diphenyl-1,3,4- oxadiazole and a crystallization-resistant tert-butyl functional group; c-phen: a 1,10-phenanthroline derivative containing a hole-transporting functional group of carbazole and a crystallization-resistant 2-ethylhexyl functional group. Both of them are amorphous and possess high thermal stability with 5% weight-reduction temperatures (ΔT5%) of 386°C and 383°C, and glass-transition temperatures (Tg) of 267°C and 195°C respectively. They were used as phosphorescent dopants in polymer light-emitting diodes (PLEDs) fabricated by solution-processed technology with configuration of ITO/PEDOT:PSS/PVK:PBD:iridium complex/TPBI/CsF/Al. At the optimal doping concentration of 2.0 wt%, the corresponding PLEDs exhibited the maximum current efficiencies of 9.1 cd A-1 and 10.0 cd A -1, the maximum external quantum efficiencies of 6.5% and 7.1%, and the maximum luminance of 2314 cd m-2 and 3157 cd m-2 respectively, with the same CIE coordinates of (0.57, 0.40). The results indicate that cationic iridium complexes are promising candidates for PLED applications when they are designed reasonably. © 2012 Elsevier B.V. All rights reserved.",
        "keywords": [
            "carbazole",
            "cationic iridium complex",
            "oxadiazole",
            "polymer light-emitting diode"
        ],
        "authors": [
            {
                "name": "Huaijun Tang",
                "org": "Yunnan University(Yunnan University),Kunming,China"
            },
            {
                "name": "Yanhu Li",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Baofeng Zhao",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Wei Yang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Hongbin Wu",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Yong Cao",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            }
        ],
        "venue": "Organic Electronics: physics, materials, applications",
        "year": 2012
    },
    "oZtlfhMy": {
        "id": "oZtlfhMy",
        "title": "Spectrally stable deep blue-emitting polyfluorenes containing dibenzothiophene-S,S-dioxide moiety",
        "abstract": "",
        "keywords": [
            "spine",
            "quantum efficiency",
            "polymers",
            "fabrication",
            "electrons",
            "free space optics",
            "displays",
            "electroluminescence",
            "annealing",
            "external quantum efficiency",
            "luminescence"
        ],
        "authors": [
            {
                "name": "lei ying",
                "org": "south china university of technology"
            },
            {
                "name": "yunhua xu",
                "org": "south china university of technology"
            },
            {
                "name": "na li",
                "org": "south china university of technology"
            },
            {
                "name": "jing ai yan",
                "org": "south china university of technology"
            },
            {
                "name": "yuanyuan li",
                "org": "south china university of technology"
            },
            {
                "name": "wei yang",
                "org": "south china university of technology"
            },
            {
                "name": "junbiao peng",
                "org": "south china university of technology"
            }
        ],
        "venue": "",
        "year": 2012
    },
    "lp76vpzX": {
        "id": "lp76vpzX",
        "title": "Highly efficient, red-emitting hyperbranched polymers utilizing a phenyl-isoquinoline iridium complex as the core",
        "abstract": "Red-emitting hyperbranched polymers utilizing polyfluorene (PF) and poly(fluorene-alt-carbazole) (PFCz) as the branches and the phenyl-isoquinoline iridium complex [(Piq) 2Ir(Pytz)] (where Piq is 1-phenylisoquinoline and Pytz is 3-(pyridin-2-yl)-1H-1,2,4-triazole) as the core are synthesized by a Suzuki polycondensation, using the \"A 2 + A 2 ' + B 3\" approach. The HOMO and LUMO levels of the PFCz branch are enhanced compared with those of the PF branches, indicating that the incorporation of the Cz moiety into the fluorene branches can improve hole injection in the polymers, while the potential barrier of electron injection is enlarged. The hyperbranched polymers using fluorene branches exhibit a better device performance. A maximum luminous efficiency of 6.54 cd A -1 (peak external quantum efficiency = 4.88%) at 5.4 V with CIE co-ordinates of (0.65, 0.34) is obtained from the PF-PiqIr2 polymer. The device efficiencies from the copolymers show a reduced roll-off upon an increase of the current density. © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.",
        "keywords": [
            "carbazole",
            "fluorene",
            "hyperbranched",
            "iridium complex",
            "polymers",
            "red-emission"
        ],
        "authors": [
            {
                "name": "Ting Guo",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Lei Yu",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Baofeng Zhao",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Yanhu Li",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Yun Tao",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Wei Yang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Qiong Hou",
                "org": "South China Normal University(South China Normal University),Guangzhou,China"
            },
            {
                "name": "Hongbin Wu",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Yong Cao",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            }
        ],
        "venue": "Macromolecular Chemistry and Physics",
        "year": 2012
    },
    "PwmklhyD": {
        "id": "PwmklhyD",
        "title": "Efficient hybrid white polymer light-emitting devices with electroluminescence covered the entire visible range and reduced efficiency roll-off",
        "abstract": "We report efficient hybrid white polymer light emitting devices (WPLEDs) fabricated via simple solution-proceeded process from a newly synthesized wide band-gap fluorene-co-dibenzothiophene-S,S-dioxide copolymer, which dually function as fluorescent blue emitter and host material for electrophosphorescent sky-blue, yellow, and saturated-red dyes. The Commission Internationale d'nclairage coordinates of the best devices are (0.356, 0.334), with electroluminescence covered the entire visible light spectrum from 400 to 780 nm, resulting in a high color rendering index of 90. Incorporation of a bilayer electrode consisting of water/alcohol-soluble conjugated polymer and Al as electron-injection cathode boosts an enhancement of 50% in device efficiency, leading to external quantum efficiency of 12.6%, and peak power efficiency of 21.4 l m W -1 as measured in an integrating sphere. Both the efficiency and the color quality of the obtained device are ranking among one of the highest values for WPLEDs reported to date. Furthermore, as compared with those all-phosphorescent WPLEDs, the hybrid WPLEDs studied here exhibit a significantly reduced efficiency roll-off due to the very low doping concentration. © 2012 American Institute of Physics.",
        "keywords": [],
        "authors": [
            {
                "name": "Sujun Hu",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Minrong Zhu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Qinghua Zou",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Hongbin Wu",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Chuluo Yang",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Waiyeung Wong",
                "org": "Hong Kong Baptist University(Hong Kong Baptist University),Hong Kong,China"
            },
            {
                "name": "Wei Yang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Junbiao Peng",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Yong Cao",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            }
        ],
        "venue": "Applied Physics Letters",
        "year": 2012
    },
    "MrH1Ldjo": {
        "id": "MrH1Ldjo",
        "title": "Highly efficient polymer solar cells based on poly(carbazole-alt-thiophene- benzofurazan)",
        "abstract": "An octyloxy substituted benzofurazan based poly(carbazole-alt-thiophene- benzofurazan) (PCzDTBF) was synthesized by Suzuki polycondensation. The absorption spectra of the polymer were peaked at 385 and 540 nm, and the HOMO and LUMO energy levels were -5.34 and -3.46 eV, respectively. The hole mobility was found to be 4.8 × 10-4 cm2 V-1 S -1 by the space charge limited current (SCLC) method, and the surface energy (Es) was calculated to be 35.8 mJ m-2 from the contact-angle measurement. Polymer solar cells (PSCs) based on the blend of PCzDTBF and PCBM with a weight ratio of 1 : 2 were fabricated. The devices were found to have a power conversion efficiency (PCE) of 4.2% in the device configuration of ITO/PSS:PEDOT/PCzDTBF:PC70BM/Al. By utilizing poly[(9,9-dioctyl-2,7-fluorene)-alt-(9,9-bis(3′-(N,N-dimethylamino)propyl) -2,7-fluorene)] (PFN) as the cathode interfacial layer, the PCE was enhanced to 5.48%, with an open-circuit voltage (Voc) of 0.90 V, a short-circuit current density (Jsc) of 7.73 mA cm-2, and a fill factor (FF) of 67%. The high efficiencies could be ascribed to the good morphology, resulting from the matched surface energies of the PCzDTBF and PCBM components, and the distinct enhancement on Voc and FF by the PFN layer, where it is possible that a built-in field potential exists between the active layer and cathode. This journal is © 2012 The Royal Society of Chemistry and the Centre National de la Recherche Scientifique.",
        "keywords": [],
        "authors": [
            {
                "name": "Bin Zhang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Xiaowen Hu",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "MinQuan Wang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Huiping Xiao",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Xiong Gong",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Wei Yang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Yong Cao",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            }
        ],
        "venue": "New Journal of Chemistry",
        "year": 2012
    },
    "vBA0GKJq": {
        "id": "vBA0GKJq",
        "title": "Novel green light-emitting polyfluorenes containing dibenzothiophene-S,S- dioxide-arylamine derivatives",
        "abstract": "Green light-emitting polyfluorenes were synthesized by Suzuki polycondensation via introducing dibenzothiophene-S,S-dioxide-(di-)tri- phenylamine (G 1 and G 2) moieties and dibenzothiophene-S,S- dioxide (SO) unit into the polyfluorene backbone, respectively. PF-SO-G copolymers show a high thermal stability and a moderate photoluminescence quantum yield in the range of 20-40%. The lowest unoccupied molecular orbital (LUMO) levels reduce with increasing the content of SO unit in the polymers. The efficient energy transfer from fluorene segment to G 1 or G 2 unit occurred in the PL process, and the EL emission peaked at about 510 nm was exclusively from G 1 or G 2 unit. Incorporating SO unit into the polymer backbone makes the device performances improved. The maximal luminous efficiency of 9.0 cd A -1 with the CIE coordinates of (0.27, 0.56) was obtained for PF-SO15-G 25 based on a single-layered device of ITO/PEDOT:PSS/polymer/CsF/Al. And the polymers (PF-SO15-G5)s exhibited a dramatic LE stability at high current densities, even though at the current density of 200 mA cm -2, the luminous efficiencies only dropped 10%. SO unit lowers the LUMO level, balances the injection and transportation of both electron and hole in the polymers, and therefore improves the device performances. The hole- and electron-only devices show that the hole and electron flux are well balanced, which demonstrates that (PF-SO15-G5)s are bipolar polymers with a balanced charge carrier transport. © 2011 Elsevier Ltd. All rights reserved.",
        "keywords": [
            "dibenzothiophene-s",
            "s-dioxide",
            "s-dioxide-arylamine",
            "polyfluorene"
        ],
        "authors": [
            {
                "name": "Huiping Xiao",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Lei Yu",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Yanhu Li",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Wen Yang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Bin Zhang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Wei Yang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Hongbin Wu",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Yong Cao",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            }
        ],
        "venue": "Polymer (United Kingdom)",
        "year": 2012
    },
    "vqOsELlR": {
        "id": "vqOsELlR",
        "title": "Efficient white emitting copolymers based on bipolar fluorene-co- dibenzothiophene-S,S-dioxide-co-carbazole backbone",
        "abstract": "Efficient white light emitting polymers were synthesized based on poly(9,9-dioctylfluorene-co-dibenzothiophene-S,S-dioxide) as blue emitter and a bisphenylamine functionalized 2,1,3-benzothiadiazole (DPABT) as red emitter. It was found that the incorporation of hole-transporting carbazole moiety into polymer main chain could effectively reduce the hole injection barriers, which can lead to distinctly improved charge balance in the emissive layer. Additionally, the holetransporting carbazole units may form efficient bipolar host with electron-transporting dibenzothiophene-S,S-dioxide units. The white light emitting diodes based on single polymer PFSOCzDPABT showed the maximum luminous efficiency of 3.3 cd/A with the maximum luminance of 10282 cd/m 2, and the luminous efficiency showed only 24% roll off at current density of 400 mA/cm2. These Commission Internationale d'Enclairage (CIE) coordinates of the devices changed slightly with the driving voltages increasing from 8 V to 12 V, and were very close to National Television System Committee (NTSC) standard white light emission of (0.33, 0.33). The results indicated that the incorporating bipolar host and low band gap DPABT unit was a promising way to achieve efficient single white light emitting copolymers. © 2013 Chinese Chemical Society, Institute of Chemistry, Chinese Academy of Sciences and Springer-Verlag Berlin Heidelberg.",
        "keywords": [
            "Carbazole",
            "Dibenzothiophene-S",
            "S-dioxide",
            "Fluorene",
            "White emitting polymer"
        ],
        "authors": [
            {
                "name": "Lei Ying",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Yanhu Li",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Caihong Wei",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "MinQuan Wang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Wei Yang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Hongbin Wu",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Yong Cao",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            }
        ],
        "venue": "Chinese Journal of Polymer Science (English Edition)",
        "year": 2013
    },
    "2Y0bdUGH": {
        "id": "2Y0bdUGH",
        "title": "Red, green, and blue light-emitting polyfluorenes containing a dibenzothiophene-S,S-dioxide unit and efficient high-color-rendering-index white-light-emitting diodes made therefrom",
        "abstract": "A series of blue (B), green (G) and red (R) light-emitting, 9,9-bis(4-(2-ethyl-hexyloxy)phenyl)fluorene (PPF) based polymers containing a dibenzothiophene-S,S-dioxide (SO) unit (PPF-SO polymer), with an additional benzothiadiazole (BT) unit (PPF-SO-BT polymer) or a 4,7-di(4-hexylthien-2-yl)- benzothiadiazole (DHTBT) unit (PPF-SO-DHTBT polymer) are synthesized. These polymers exhibit high fluorescence yields and good thermal stability. Light-emitting diodes (LEDs) using PPF-SO25, PPF-SO15-BT1, and PPF-SO15-DHTBT1 as emission polymers have maximum efficiencies LEmax = 7.0, 17.6 and 6.1 cd A-1 with CIE coordinates (0.15, 0.17), (0.37, 0.56) and (0.62, 0.36), respectively. 1D distributed feedback lasers using PPF-SO30 as the gain medium are demonstrated, with a wavelength tuning range 467 to 487 nm and low pump energy thresholds (≥18 nJ). Blending different ratios of B (PPF-SO), G (PPF-SO-BT) and R (PPF-SO-DHTBT) polymers allows highly efficient white polymer light-emitting diodes (WPLEDs) to be realized. The optimized devices have an attractive color temperature close to 4700 K and an excellent color rendering index (CRI) ≥90. They are relatively stable, with the emission color remaining almost unchanged when the current densities increase from 20 to 260 mA cm-2. The use of these polymers enables WPLEDs with a superior trade-off between device efficiency, CRI, and color stability. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.",
        "keywords": [
            "polyfluorene",
            "polymer light-emitting diodes",
            "rgbw emission"
        ],
        "authors": [
            {
                "name": "Lei Yu",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Jie Liu",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Sujun Hu",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Ruifeng He",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Wei Yang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Hongbin Wu",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Junbiao Peng",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Ruidong Xia",
                "org": "Imperial College London(Imperial College,Imperial College London),London,United Kingdom"
            },
            {
                "name": "Donal D C Bradley",
                "org": "Imperial College London(Imperial College,Imperial College London),London,United Kingdom"
            }
        ],
        "venue": "Advanced Functional Materials",
        "year": 2013
    },
    "MPkkA9Jo": {
        "id": "MPkkA9Jo",
        "title": "Highly efficient single-layer organic light-emitting devices using cationic iridium complex as host",
        "abstract": "Highly efficient single-layer organic light-emitting devices (OLEDs) based on blended cationic Ir complexes as emitting layer have been demonstrated using narrow band gap cationic Ir complex [Ir(Meppy)2(pybm)](PF 6) (C1) as guest and wide band gap cationic Ir complex [Ir(dfppy)2(tzpy-cn)](PF6) (C2) as host. As compared with single cationic Ir complex emitting layer, these host-guest systems exhibit highly enhanced efficiencies, with maximum luminous efficiency of 25.7 cd/A, external quantum efficiency of 8.6%, which are nearly 3-folds of those of pure C1-based device. Compared with a multilayer host-free device containing C1 as emitting layer and TPBI as electron-transporting and hole-blocking layer, the above single-layer devices also show 2-folds enhancement efficiencies. The high efficiencies achieved in these host-guest systems are among the highest values reported for ionic Ir complexes-based solid-state light-emitting devices. In addition, a white-similar emission with CIE of (0.36, 0.47) has also been achieved with luminous efficiency of 4.2 cd/A as the C1 concentration is 0.1 wt.%. The results demonstrate that the ionic Ir complexes-based host-guest system provides a new approach to achieve highly efficient OLEDs upon single-layer device structure and solution-processing technique. © 2012 Elsevier B.V. All rights reserved.",
        "keywords": [
            "ionic ir complex",
            "ir complexes host-guest system",
            "organic light-emitting devices",
            "phosphorescent ir complex"
        ],
        "authors": [
            {
                "name": "Bing Chen",
                "org": "Wuhan Institute of Physics and Mathematics Chinese Academy of Sciences(Academia Sinica,Wuhan Inst of Physics,Wuhan Institute of Physics and Mathematics),Wuhan,China"
            },
            {
                "name": "Yanhu Li",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Yueying Chu",
                "org": "Wuhan Institute of Physics and Mathematics Chinese Academy of Sciences(Academia Sinica,Wuhan Inst of Physics,Wuhan Institute of Physics and Mathematics),Wuhan,China"
            },
            {
                "name": "Anmin Zheng",
                "org": "Wuhan Institute of Physics and Mathematics Chinese Academy of Sciences(Academia Sinica,Wuhan Inst of Physics,Wuhan Institute of Physics and Mathematics),Wuhan,China"
            },
            {
                "name": "Jiwen Feng",
                "org": "Wuhan Institute of Physics and Mathematics Chinese Academy of Sciences(Academia Sinica,Wuhan Inst of Physics,Wuhan Institute of Physics and Mathematics),Wuhan,China"
            },
            {
                "name": "Zhitian Liu",
                "org": "Wuhan Institute of Technology(Wuhan Institute of Technology,Wuhan Institute of Chemical Technology,Wuhan Inst. of Chemical Technology),Wuhan,China"
            },
            {
                "name": "Hongbin Wu",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Wei Yang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            }
        ],
        "venue": "Organic Electronics: physics, materials, applications",
        "year": 2013
    },
    "2SaIClFZ": {
        "id": "2SaIClFZ",
        "title": "Alcohol-soluble polyfluorenes containing dibenzothiophene-S,S-dioxide segments for cathode interfacial layer in PLEDs and PSCs",
        "abstract": "A series of alcohol-soluble amino-functionalized polyfluorene derivatives (PF-N-S, PF-N-SC8 and PF-N-SOC8) comprising various ratios of dibenzothiophene-S,S-dioxide segments (S/SC8/SOC8) in the main chains, respectively, were synthesized and utilized as cathode interfacial layer (CIL) in polymer light-emitting diodes (PLEDs) and polymer solar cells (PSCs) with high-work-function Al (or Au) electrode. The polymers possess LUMO/HOMO levels at -2.78 to -3.53 eV/-5.69 to -6.32 eV. Multilayer PLEDs and PSCs with device configurations of ITO/PEDOT:PSS (40 nm)/P-PPV or PFO-DBT35:PCBM = 1:2 (80 nm)/CIL (3-15 nm)/Al (or Au) (100 nm) were fabricated. The PF-N-S-10/Al (or Au) cathode PLEDs displayed maximum luminous efficiency of 24.4 cd A-1 (or 11.9 cd A-1), significantly higher than bare Al (or Au) cathode device, exceeding well-known Ba/Al and poly[(9,9-bis(3��-(N,N- dimethylamino)propyl)-2,7-fluorene)-alt-2,7-(9,9-dioctylfluorene)] (PFN)/Al (or PFN/Au) cathode devices. The enhanced open-circuit voltages (Vocs), electron reflux and reduced work functions clarify that the electron injection barrier from the Al (or Au) electrode can be lowered by inserting the polymers as CIL. The resulted PSCs also show device performances exceeding Al and PFN/Al cathode devices. The results indicate that PF-N-S, PF-N-SC8 and PF-N-SOC8 are excellent CIL materials for PLEDs and PSCs with high-work-function Al or Au electrode. ? 2014 Elsevier B.V. All rights reserved.",
        "keywords": [
            "amino-functionalized polyfluorene derivatives",
            "cathode interfacial layer",
            "dibenzothiophene-s",
            "s-dioxide",
            "polymer light-emitting diode",
            "polymer solar cell"
        ],
        "authors": [
            {
                "name": "Huiping Xiao",
                "org": "Nanchang Hangkong University(Nanchang Hangkong University),Nanchang,China"
            },
            {
                "name": "Jingsheng Miao",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Jiaqing Cao",
                "org": "Nanchang Hangkong University(Nanchang Hangkong University),Nanchang,China"
            },
            {
                "name": "Wei Yang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Hongbin Wu",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Yong Cao",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            }
        ],
        "venue": "Organic Electronics: physics, materials, applications",
        "year": 2014
    },
    "mecGiIIw": {
        "id": "mecGiIIw",
        "title": "Novel heteroleptic iridium(III) complexes with a 2-(1H-pyrazol-5-yl) pyridine derivative containing a carbazole group as ancillary ligand: Synthesis and application for polymer light-emitting diodes",
        "abstract": "A novel organic compound 9-(2-ethylhexyl)-3-(5-(pyridin-2-yl)-1H-pyrazol-3- yl)-9H-carbazole (PPC) was synthesized and used as ancillary ligand in heteroleptic iridium(III) complexes (npy)2Ir(PPC), (ppy) 2Ir(PPC) and (dfppy)2Ir(PPC) (npy: 2-(naphthalen-1-yl) pyridine; ppy: 2-phenylpyridine; dfppy: 2-(2,4-difluorophenyl)pyridine). All of the iridium(III) complexes are amorphous and have high thermal stability. Their glass-transition temperatures are 171 C, 172 C and 165 C, and 5% weight-reduction temperatures are 411 C, 406 C and 433 C, respectively. The polymer light-emitting diodes using the iridium(III) complexes as phosphorescent dopants exhibited good EL performance, the maximum luminances of (npy) 2Ir(PPC), (ppy)2Ir(PPC) and (dfppy)2Ir(PPC) are 4948 cd m-2, 11215 cd m-2 and 4696 cd m-2, and the maximum current efficiencies are 11.6 cd A-1, 25.2 cd A -1 and 16.4 cd A-1, respectively. The CIEs of their devices are around (0.59, 0.40), (0.31, 0.57) and (0.32, 0.54), respectively. ? 2013 Elsevier B.V. All rights reserved.",
        "keywords": [
            "Ancillary ligand",
            "Carbazole",
            "Heteroleptic iridium(III) complex",
            "Polymer light-emitting diode",
            "Pyrazole"
        ],
        "authors": [
            {
                "name": "Huaijun Tang",
                "org": "Yunnan University(Yunnan University),Kunming,China"
            },
            {
                "name": "Liying Wei",
                "org": "Yunnan University(Yunnan University),Kunming,China"
            },
            {
                "name": "Jianbin Wang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Yanhu Li",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Hongbin Wu",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Wei Yang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Yong Cao",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            }
        ],
        "venue": "Synthetic Metals",
        "year": 2014
    },
    "keE4h364": {
        "id": "keE4h364",
        "title": "Polymer light-emitting diodes based on cationic iridium(III) complexes with a 1,10-phenanthroline derivative containing a bipolar carbazole–oxadiazole unit as the auxiliary ligand",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "huaijun tang",
                "org": ""
            },
            {
                "name": "liying wei",
                "org": ""
            },
            {
                "name": "guoyun meng",
                "org": ""
            },
            {
                "name": "yanhu li",
                "org": ""
            },
            {
                "name": "guanze wang",
                "org": ""
            },
            {
                "name": "furui yang",
                "org": ""
            },
            {
                "name": "hongbin wu",
                "org": ""
            },
            {
                "name": "wei yang",
                "org": ""
            },
            {
                "name": "yong cao",
                "org": ""
            }
        ],
        "venue": "Optical Materials",
        "year": 2014
    },
    "Ea1uGmQO": {
        "id": "Ea1uGmQO",
        "title": "Dibenzothiophene- S,S -dioxide based medium-band-gap polymers for efficient bulk heterojunction solar cells",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "ruifeng he",
                "org": ""
            },
            {
                "name": "jin xu",
                "org": ""
            },
            {
                "name": "yong yang",
                "org": ""
            },
            {
                "name": "ping cai",
                "org": ""
            },
            {
                "name": "dongcheng chen",
                "org": ""
            },
            {
                "name": "lei ying",
                "org": ""
            },
            {
                "name": "wei yang",
                "org": ""
            },
            {
                "name": "yong cao",
                "org": ""
            }
        ],
        "venue": "Organic Electronics",
        "year": 2014
    },
    "fqlReXPy": {
        "id": "fqlReXPy",
        "title": "Improved electroluminescence efficiency of polyfluorenes by simultaneously incorporating dibenzothiophene- S,S -dioxide unit in main chain and oxadiazole moiety in side chain",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "yong yang",
                "org": ""
            },
            {
                "name": "lei yu",
                "org": ""
            },
            {
                "name": "yong xue",
                "org": ""
            },
            {
                "name": "qinghua zou",
                "org": ""
            },
            {
                "name": "bin zhang",
                "org": ""
            },
            {
                "name": "lei ying",
                "org": ""
            },
            {
                "name": "wei yang",
                "org": ""
            },
            {
                "name": "junbiao peng",
                "org": ""
            },
            {
                "name": "yong cao",
                "org": ""
            }
        ],
        "venue": "Polymer",
        "year": 2014
    },
    "6Fr9yBEC": {
        "id": "6Fr9yBEC",
        "title": "Indolo[3,2-b]carbazole and benzofurazan based narrow band-gap polymers for photovoltaic cells",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "bin zhang",
                "org": "south china university of technology"
            },
            {
                "name": "lei yu",
                "org": "south china university of technology"
            },
            {
                "name": "li fan",
                "org": "south china university of technology"
            },
            {
                "name": "na wang",
                "org": "south china university of technology"
            },
            {
                "name": "liwen hu",
                "org": "south china university of technology"
            },
            {
                "name": "wei yang",
                "org": "south china university of technology"
            }
        ],
        "venue": "New Journal of Chemistry",
        "year": 2014
    },
    "fWEmbkNX": {
        "id": "fWEmbkNX",
        "title": "Narrow-Band-Gap Conjugated Polymers Based on 2,7-Dioctyl-Substituted Dibenzo[ a,c ]phenazine Derivatives for Polymer Solar Cells",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "jin xu",
                "org": ""
            },
            {
                "name": "feng peng",
                "org": ""
            },
            {
                "name": "lei yu",
                "org": ""
            },
            {
                "name": "ruifeng he",
                "org": ""
            },
            {
                "name": "yong cao",
                "org": ""
            },
            {
                "name": "wei yang",
                "org": ""
            },
            {
                "name": "junwu chen",
                "org": ""
            },
            {
                "name": "ping cai",
                "org": ""
            },
            {
                "name": "lei ying",
                "org": ""
            }
        ],
        "venue": "Macromolecules",
        "year": 2014
    },
    "0HvgJI2P": {
        "id": "0HvgJI2P",
        "title": "Efficient ��-conjugated interrupted host polymer by metal-free polymerization for blue/green phosphorescent light-emitting diodes",
        "abstract": "A new aromatic host polymer poly{[1,4-bis(9-decylcarbazole-3-yl)-2,3,5,6- tetrafluorobenzene-3,3��-diyl]-alt-[N-methylisatin-2-one-3,3-diyl]} (PICzFB) containing carbazole-tetrafluorinebeneze-carbazole moiety in the ��-conjugated interrupted polymer backbone was synthesized by superacid-catalyzed metal-free polyhydroxyalkylation. The resulted copolymer PICzFB showed a comparatively wide band gap up to 3.32 eV and high triplet energy (ET) of 2.73 eV due to confined conjugation by the ��?��?C bond interrupted polymer backbone. Blue and green light-emitting devices with PICzFB as host, FIrpic and Ir(mppy)3 as phosphorescent dopants showed the maximum luminous efficiencies of 5.0 and 27.6 cd/A, respectively. The results suggested that the strategy of incorporating bipolar unit into the ��-conjugated interrupted polymer backbone can be a promising approach to obtain host polymer with high triplet level for solution-processed blue and green phosphorescent polymer light-emitting diodes. ? 2014 Wiley Periodicals, Inc.",
        "keywords": [
            "phosphorescent host polymer",
            "polycondensation",
            "polymer light-emitting diode (PLED)",
            "super acid-catalyzed polyhydroxyalkylation"
        ],
        "authors": [
            {
                "name": "Bing Chen",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Lei Yu",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Biaolan Liu",
                "org": "Wuhan Institute of Physics and Mathematics Chinese Academy of Sciences(Academia Sinica,Wuhan Inst of Physics,Wuhan Institute of Physics and Mathematics),Wuhan,China"
            },
            {
                "name": "Jiwen Feng",
                "org": "Wuhan Institute of Physics and Mathematics Chinese Academy of Sciences(Academia Sinica,Wuhan Inst of Physics,Wuhan Institute of Physics and Mathematics),Wuhan,China"
            },
            {
                "name": "Zhitian Liu",
                "org": "Wuhan Institute of Technology(Wuhan Institute of Technology,Wuhan Institute of Chemical Technology,Wuhan Inst. of Chemical Technology),Wuhan,China"
            },
            {
                "name": "Lei Ying",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Yanhu Li",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            },
            {
                "name": "Wei Yang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            }
        ],
        "venue": "Journal of Polymer Science, Part A: Polymer Chemistry",
        "year": 2014
    },
    "grtT5os0": {
        "id": "grtT5os0",
        "title": "Bipolar π-conjugation interrupted host polymers by metal-free superacid-catalyzed polymerization for single-layer electrophosphorescent diodes",
        "abstract": "",
        "keywords": [
            "light emitting diodes",
            "physical sciences",
            "oleds",
            "energy transfer",
            "chemistry",
            "copolymers",
            "green",
            "units"
        ],
        "authors": [
            {
                "name": "bing chen",
                "org": "chinese academy of sciences"
            },
            {
                "name": "zhanhai xiao",
                "org": "wuhan university of technology"
            },
            {
                "name": "yanhu li",
                "org": "south china university of technology"
            },
            {
                "name": "lei yu",
                "org": "south china university of technology"
            },
            {
                "name": "wei yang",
                "org": "south china university of technology"
            },
            {
                "name": "jiwen feng",
                "org": "chinese academy of sciences"
            }
        ],
        "venue": "",
        "year": 2014
    },
    "yo2tBmVn": {
        "id": "yo2tBmVn",
        "title": "Efficient yellow–green light-emitting cationic iridium complexes based on 1,10-phenanthroline derivatives containing oxadiazole-triphenylamine unit",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "huaijun tang",
                "org": ""
            },
            {
                "name": "yanhu li",
                "org": ""
            },
            {
                "name": "qiliang chen",
                "org": ""
            },
            {
                "name": "bing chen",
                "org": ""
            },
            {
                "name": "qiquan qiao",
                "org": ""
            },
            {
                "name": "wei yang",
                "org": ""
            },
            {
                "name": "hongbin wu",
                "org": ""
            },
            {
                "name": "yong cao",
                "org": ""
            }
        ],
        "venue": "Dyes and Pigments",
        "year": 2014
    },
    "P82TTeDM": {
        "id": "P82TTeDM",
        "title": "Efficient π‐conjugated interrupted host polymer by metal‐free polymerization for blue/green phosphorescent light‐emitting diodes",
        "abstract": "",
        "keywords": [
            "polycondensation"
        ],
        "authors": [
            {
                "name": "bing chen",
                "org": "south china university of technology"
            },
            {
                "name": "lei yu",
                "org": "south china university of technology"
            },
            {
                "name": "biaolan liu",
                "org": "chinese academy of sciences"
            },
            {
                "name": "jiwen feng",
                "org": "chinese academy of sciences"
            },
            {
                "name": "zhitian liu",
                "org": "wuhan institute of technology"
            },
            {
                "name": "lei ying",
                "org": "south china university of technology"
            },
            {
                "name": "yanhu li",
                "org": "south china university of technology"
            },
            {
                "name": "wei yang",
                "org": "south china university of technology"
            }
        ],
        "venue": "Journal of Polymer Science Part A",
        "year": 2014
    },
    "jxmhxGNY": {
        "id": "jxmhxGNY",
        "title": "Improving the efficiency and spectral stability of white-emitting polycarbazoles by introducing a dibenzothiophene-S,S-dioxide unit into the backbone",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "ruifeng he",
                "org": "south china university of technology"
            },
            {
                "name": "jin xu",
                "org": "south china university of technology"
            },
            {
                "name": "yong xue",
                "org": "south china university of technology"
            },
            {
                "name": "dongcheng chen",
                "org": "south china university of technology"
            },
            {
                "name": "lei ying",
                "org": "south china university of technology"
            },
            {
                "name": "wei yang",
                "org": "south china university of technology"
            },
            {
                "name": "yong cao",
                "org": "south china university of technology"
            }
        ],
        "venue": "",
        "year": 2014
    },
    "CepdO8J9": {
        "id": "CepdO8J9",
        "title": "Absorption-enhanced polymer solar cells based on broad band-gap poly(triphenylamine-alt-benzo[c][1,2,5]selenadiazole) derivative",
        "abstract": "A triphenylamine and benzo[c][1,2,5]selenadiazole based broad band-gap polymer PTPADTSe was synthesized by Suzuki polycondensation. The thermal, photophysical, electrochemical, and photovoltaic properties were characterized in detail. The polymer showed a high thermal stability with the decomposition temperature at 377 degrees C. The absorption peaks of PTPADTSe in film were located at 359 and 561 nm with the optical bang gap of 1.84 eV. Through the cyclic voltammogram measurement, it gave the highest occupied molecular orbit (HOMO) energy level of -5.14 eV. The polymer solar cell was fabricated under the device structure of ITO/PSS:PEDOT/PTPADTSe: PC61BM/LiF/Al, where it displayed the photovoltaic performance with the short circuit current density (J(sc)) of 1.32 mA cm(-2), open circuit voltage (V-oc) of 0.81 V, fill factor (FF) of 35% and power conversion efficiency (PCE) of 0.52%, respectively. (C) 2015 Elsevier B.V. All rights reserved.",
        "keywords": [
            "EFFICIENCY",
            "PHOTOVOLTAICS",
            "COPOLYMER",
            "DESIGN",
            "DONORS"
        ],
        "authors": [
            {
                "name": "bin zhang",
                "org": ""
            },
            {
                "name": "jin xu",
                "org": ""
            },
            {
                "name": "liwen hu",
                "org": ""
            },
            {
                "name": "guiting chen",
                "org": ""
            },
            {
                "name": "wei yang",
                "org": ""
            }
        ],
        "venue": "MATERIALS LETTERS",
        "year": 2015
    },
    "QJpCnJHo": {
        "id": "QJpCnJHo",
        "title": "Blue light‐emitting hyperbranched polymers using fluorene‐co‐dibenzothiophene‐S,S‐dioxide as branches",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "ting guo",
                "org": "south china university of technology"
            },
            {
                "name": "lei yu",
                "org": "south china university of technology"
            },
            {
                "name": "baofeng zhao",
                "org": "south china university of technology"
            },
            {
                "name": "lei ying",
                "org": "south china university of technology"
            },
            {
                "name": "hongbin wu",
                "org": "south china university of technology"
            },
            {
                "name": "wei yang",
                "org": "south china university of technology"
            },
            {
                "name": "yong cao",
                "org": "south china university of technology"
            }
        ],
        "venue": "Journal of Polymer Science Part A",
        "year": 2015
    },
    "is1zQuwR": {
        "id": "is1zQuwR",
        "title": "Efficient binary white light-emitting polymers grafted with iridium complexes as side groups",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "ting guo",
                "org": "south china university of technology"
            },
            {
                "name": "wenkai zhong",
                "org": "south china university of technology"
            },
            {
                "name": "jianhua zou",
                "org": "south china university of technology"
            },
            {
                "name": "lei ying",
                "org": "south china university of technology"
            },
            {
                "name": "wei yang",
                "org": "south china university of technology"
            },
            {
                "name": "junbiao peng",
                "org": "south china university of technology"
            }
        ],
        "venue": "",
        "year": 2015
    },
    "ZgJpOc8H": {
        "id": "ZgJpOc8H",
        "title": "Feasible energy level tuning in polymer solar cells based on broad band-gap polytriphenylamine derivatives",
        "abstract": "A series of versatile broad band-gap alternating copolymers (P1, P2, P3 and P4) based on triphenylamine (TPA) and benzofurazan derivatives, differing in the substituted groups [-OC8H17, -C8H17, -CF3, -(CF3)(2)] in their triphenylamine units, were designed and synthesized by Suzuki polycondensation. The relationships between the substituted groups in TPA and the highest occupied molecular orbital (HOMO) energy levels, as well as the open circuit voltages (V(oc)s), were investigated in detail. The HOMO levels of these four polymers decreased sequentially when the substituted groups shifted from electron-donating groups [-OC8H17, -C8H17] to electron-withdrawing groups [-CF3, -(CF3)(2)], which Led to the successive increase in V(oc)s of the polymer sollar cells (PSCs) based on these polymers. Through the characterization of photovoltaic performance, the highest V-oc, which reached up to 1.00 V, was achieved by the polymer with bis(trifluoromenthyl) substituted group (P4), which is one of the highest V based on polytriphenyl-amine derived polymers for PSCs. Among these polymers, the one with octyl side chain (P2) showed the best photovoltaic performance with the highest short circuit current density (J(sc)) and fill factor (FF), giving a J(sc) of 4.84 mA cm(-2), FF of 50%, V-oc, of 0.80 V and power conversion efficiency (PCE) of 2.22%.",
        "keywords": [
            "OPEN-CIRCUIT VOLTAGE",
            "PHOTOVOLTAIC PROPERTIES",
            "HIGH-EFFICIENCY",
            "CONVERSION EFFICIENCY",
            "CONJUGATED POLYMERS",
            "CURRENT-DENSITY",
            "SIDE-CHAINS",
            "FILL FACTOR",
            "PERFORMANCE",
            "BENZOTHIADIAZOLE"
        ],
        "authors": [
            {
                "name": "bin zhang",
                "org": "shenzhen university"
            },
            {
                "name": "guiting chen",
                "org": "south china university of technology"
            },
            {
                "name": "jin xu",
                "org": "south china university of technology"
            },
            {
                "name": "liwen hu",
                "org": "south china university of technology"
            },
            {
                "name": "wei yang",
                "org": "south china university of technology"
            }
        ],
        "venue": "NEW JOURNAL OF CHEMISTRY",
        "year": 2015
    },
    "bxehVtOz": {
        "id": "bxehVtOz",
        "title": "The effects of solvent vapor annealing on the performance of blue polymer light-emitting diodes",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "junfei liang",
                "org": ""
            },
            {
                "name": "wenkai zhong",
                "org": ""
            },
            {
                "name": "lei ying",
                "org": ""
            },
            {
                "name": "wei yang",
                "org": ""
            },
            {
                "name": "junbiao peng",
                "org": ""
            },
            {
                "name": "yong cao",
                "org": ""
            }
        ],
        "venue": "Organic Electronics",
        "year": 2015
    },
    "O0d1IMn1": {
        "id": "O0d1IMn1",
        "title": "Hyperbranched red light-emitting phosphorescent polymers based on iridium complex as the core",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "ting guo",
                "org": ""
            },
            {
                "name": "lei yu",
                "org": ""
            },
            {
                "name": "yong yang",
                "org": ""
            },
            {
                "name": "yanhu li",
                "org": ""
            },
            {
                "name": "yun tao",
                "org": ""
            },
            {
                "name": "qiong hou",
                "org": ""
            },
            {
                "name": "lei ying",
                "org": ""
            },
            {
                "name": "wei yang",
                "org": ""
            },
            {
                "name": "hongbin wu",
                "org": ""
            },
            {
                "name": "yong cao",
                "org": ""
            }
        ],
        "venue": "Journal of Luminescence",
        "year": 2015
    },
    "FKoegqLV": {
        "id": "FKoegqLV",
        "title": "Efficient saturated red light-emitting polyfluorenes containing iridium complexes in side chains",
        "abstract": "A series of electrophosphorescent copolymers were synthesized by Suzuki polymerization. A diketone-ended alkyl chain which is grafted in the N-position of the carbazole unit is used as a ligand to form a pendant cyclometalated Ir complex with 1-(9,9-dioctyl-9H-fluoren-2-yl)isoquinoline and 1-(N,N-diphenyl-benzenamine-4-yl)isoquinoline. The electroluminescence from the backbone of the copolymers is completely quenched by tethered iridium complexes even though with the content of iridium complexes being as low as 1 mol%. Saturated red light-emitting diodes were fabricated on the basis of these two series of copolymers. The best device performance with a maximum external quantum efficiency of 7.8% on the basis of copolymer PF-IrNiq1 was achieved, which was among the highest efficiencies of the reported electrophosphorescent red light-emitting polymers comprising iridium ligands.",
        "keywords": [],
        "authors": [
            {
                "name": "ting guo",
                "org": "south china university of technology"
            },
            {
                "name": "wenkai zhong",
                "org": "south china university of technology"
            },
            {
                "name": "anqi zhang",
                "org": "south china university of technology"
            },
            {
                "name": "jianhua zou",
                "org": "south china university of technology"
            },
            {
                "name": "lei ying",
                "org": "south china university of technology"
            },
            {
                "name": "wei yang",
                "org": "south china university of technology"
            },
            {
                "name": "junbiao peng",
                "org": "south china university of technology"
            }
        ],
        "venue": "New Journal of Chemistry",
        "year": 2015
    },
    "X54Omlal": {
        "id": "X54Omlal",
        "title": "Color tuning in inverted blue light-emitting diodes based on a polyfluorene derivative by adjusting the thickness of the light-emitting layer",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "jin xu",
                "org": "south china university of technology"
            },
            {
                "name": "lei yu",
                "org": "south china university of technology"
            },
            {
                "name": "liwen hu",
                "org": "south china university of technology"
            },
            {
                "name": "ruifeng he",
                "org": "south china university of technology"
            },
            {
                "name": "wei yang",
                "org": "south china university of technology"
            },
            {
                "name": "junbiao peng",
                "org": "south china university of technology"
            },
            {
                "name": "yong cao",
                "org": "south china university of technology"
            }
        ],
        "venue": "",
        "year": 2015
    },
    "aW8Tc4Qj": {
        "id": "aW8Tc4Qj",
        "title": "Highly efficient non-doped single-layer blue organic light-emitting diodes based on light-emitting conjugated polymers containing trifluoren-2-ylamine and dibenzothiophene- S,S -dioxide",
        "abstract": "",
        "keywords": [
            "organic light emitting diodes",
            "electroluminescence"
        ],
        "authors": [
            {
                "name": "hua ye",
                "org": ""
            },
            {
                "name": "baofeng zhao",
                "org": ""
            },
            {
                "name": "dongyun li",
                "org": ""
            },
            {
                "name": "dongcheng chen",
                "org": ""
            },
            {
                "name": "gaozhan xie",
                "org": ""
            },
            {
                "name": "shijian su",
                "org": ""
            },
            {
                "name": "wei yang",
                "org": ""
            },
            {
                "name": "yong cao",
                "org": ""
            }
        ],
        "venue": "Synthetic Metals",
        "year": 2015
    },
    "TUmWsOX8": {
        "id": "TUmWsOX8",
        "title": "Triphenylamine-based broad band-gap polymers for bulk-heterojunction polymer solar cells",
        "abstract": "Three triphenylamine-based broad band-gap polymers P1, P2, and P3 were designed and synthesized by Suzuki polycondensation. The optical band gaps of P1, P2, and P3 were 1.90, 19.5, and 1.99 eV, respectively. The calculated highest occupied molecular orbit energy levels of P1, P2, and P3 were -5.31, -5.29, and -5.32 eV, respectively, by cyclic voltammogram characterization. The hole mobilities of P1, P2, and P3 were 1.6 x 10(-4), 5.9 x 10(-5), and 4.1 x 10(-5) cm(2) v(-1) s(-1), respectively, by the space charge-limited current method. The polymer solar cells were fabricated under the device architecture of ITO/PEDOT:PSS/polymer:PC61BM or PC71BM/(PFN)/Al. All solar cells displayed the high open circuit voltages, where the highest ones can reach 0.90 V for P1 and P2. The P1- and P2-based solar cells gave the best power conversion efficiency of 3.37 and 3.34 %, respectively.",
        "keywords": [
            "OPEN-CIRCUIT VOLTAGE",
            "POWER CONVERSION EFFICIENCY",
            "HIGH-PERFORMANCE",
            "SEMICONDUCTING POLYMERS",
            "PHOTOVOLTAIC CELLS",
            "DERIVATIVES",
            "INDOLOCARBAZOLE",
            "COPOLYMER",
            "ACCEPTOR",
            "CORE"
        ],
        "authors": [
            {
                "name": "bin zhang",
                "org": "shenzhen university"
            },
            {
                "name": "junfei liang",
                "org": "south china university of technology"
            },
            {
                "name": "liwen hu",
                "org": "south china university of technology"
            },
            {
                "name": "feng peng",
                "org": "south china university of technology"
            },
            {
                "name": "guiting chen",
                "org": "south china university of technology"
            },
            {
                "name": "wei yang",
                "org": "south china university of technology"
            }
        ],
        "venue": "JOURNAL OF MATERIALS SCIENCE",
        "year": 2015
    },
    "gxg2nNuN": {
        "id": "gxg2nNuN",
        "title": "Synthesis, Characterization and Photovoltaic Properties of Polycarbazole Derived Random Copolymers With Enhanced Light Absorption",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "liwen hu",
                "org": ""
            },
            {
                "name": "wanzhu cai",
                "org": ""
            },
            {
                "name": "wei zhao",
                "org": ""
            },
            {
                "name": "bin zhang",
                "org": ""
            },
            {
                "name": "wei yang",
                "org": ""
            }
        ],
        "venue": "Journal of Macromolecular Science, Part A",
        "year": 2015
    },
    "IARPfvkM": {
        "id": "IARPfvkM",
        "title": "Using d -limonene as the non-aromatic and non-chlorinated solvent for the fabrications of high performance polymer light-emitting diodes and field-effect transistors",
        "abstract": "",
        "keywords": [
            "organic field effect transistor"
        ],
        "authors": [
            {
                "name": "yongxiang zhu",
                "org": ""
            },
            {
                "name": "zhenhui chen",
                "org": ""
            },
            {
                "name": "yong yang",
                "org": ""
            },
            {
                "name": "ping cai",
                "org": ""
            },
            {
                "name": "junwu chen",
                "org": ""
            },
            {
                "name": "yuanyuan li",
                "org": ""
            },
            {
                "name": "wei yang",
                "org": ""
            },
            {
                "name": "junbiao peng",
                "org": ""
            },
            {
                "name": "yong cao",
                "org": ""
            }
        ],
        "venue": "Organic Electronics",
        "year": 2015
    },
    "WPGVaHQN": {
        "id": "WPGVaHQN",
        "title": "Improving Film Formation and Photovoltage of Highly Efficient Inverted‐Type Perovskite Solar Cells through the Incorporation of New Polymeric Hole Selective Layers",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "qifan xue",
                "org": "south china university of technology"
            },
            {
                "name": "guiting chen",
                "org": "south china university of technology"
            },
            {
                "name": "meiyue liu",
                "org": "south china university of technology"
            },
            {
                "name": "jingyang xiao",
                "org": "south china university of technology"
            },
            {
                "name": "ziming chen",
                "org": "south china university of technology"
            },
            {
                "name": "zhicheng hu",
                "org": "south china university of technology"
            },
            {
                "name": "xiaofang jiang",
                "org": "south china university of technology"
            },
            {
                "name": "bin zhang",
                "org": "south china university of technology"
            },
            {
                "name": "fei huang",
                "org": "south china university of technology"
            },
            {
                "name": "wei yang",
                "org": "south china university of technology"
            },
            {
                "name": "hinlap yip",
                "org": "south china university of technology"
            },
            {
                "name": "yong cao",
                "org": "south china university of technology"
            }
        ],
        "venue": "",
        "year": 2015
    },
    "3okoz2Oo": {
        "id": "3okoz2Oo",
        "title": "Effects of flanked units on optoelectronic properties of diketopyrrolopyrrole based π-conjugated polymers",
        "abstract": "",
        "keywords": [
            "polymer solar cells"
        ],
        "authors": [
            {
                "name": "jing yue",
                "org": ""
            },
            {
                "name": "junfei liang",
                "org": ""
            },
            {
                "name": "sheng sun",
                "org": ""
            },
            {
                "name": "wenkai zhong",
                "org": ""
            },
            {
                "name": "linfeng lan",
                "org": ""
            },
            {
                "name": "lei ying",
                "org": ""
            },
            {
                "name": "wei yang",
                "org": ""
            },
            {
                "name": "yong cao",
                "org": ""
            }
        ],
        "venue": "Dyes and Pigments",
        "year": 2015
    },
    "UQjJf7o7": {
        "id": "UQjJf7o7",
        "title": "Synthesis and optical and electrochemical properties of polycyclic aromatic compounds with S,S-dioxide benzothiophene fused seven rings",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "yong yang",
                "org": "south china university of technology"
            },
            {
                "name": "junfei liang",
                "org": "south china university of technology"
            },
            {
                "name": "liwen hu",
                "org": "south china university of technology"
            },
            {
                "name": "bin zhang",
                "org": "south china university of technology"
            },
            {
                "name": "wei yang",
                "org": "south china university of technology"
            }
        ],
        "venue": "New Journal of Chemistry",
        "year": 2015
    },
    "d33PBOOD": {
        "id": "d33PBOOD",
        "title": "Effects of bridge units on the properties of indolo[3,2- b ]carbazole- co -difluorobenzo[ d ][1,2,3]triazole based π -conjugated copolymers",
        "abstract": "",
        "keywords": [
            "polymer solar cells"
        ],
        "authors": [
            {
                "name": "wenkai zhong",
                "org": ""
            },
            {
                "name": "jin xu",
                "org": ""
            },
            {
                "name": "sheng sun",
                "org": ""
            },
            {
                "name": "junfei liang",
                "org": ""
            },
            {
                "name": "bin zhang",
                "org": ""
            },
            {
                "name": "ruifeng he",
                "org": ""
            },
            {
                "name": "linfeng lan",
                "org": ""
            },
            {
                "name": "fei huang",
                "org": ""
            },
            {
                "name": "lei ying",
                "org": ""
            },
            {
                "name": "wei yang",
                "org": ""
            },
            {
                "name": "junbiao peng",
                "org": ""
            },
            {
                "name": "yong cao",
                "org": ""
            }
        ],
        "venue": "Organic Electronics",
        "year": 2015
    },
    "atnt5Sdu": {
        "id": "atnt5Sdu",
        "title": "Solution-processable bipolar S,S-dioxide-dibenzothiophene chromophores for single-layer organic light-emitting diodes",
        "abstract": "A series of novel bipolar chromophores consisting of a 4-(9H-carbazole-9-yl)aniline (TCz) moiety as the electron-donating unit and an isomeric meta- or para-linked S,S-dioxide-dibenzothiophene (SO) unit as the electron-withdrawing unit were designed and synthesized. These chromophores exhibited obvious intramolecular charge transfer effects as revealed by photoluminescence spectra. All chromophores exhibited good thermal stabilities. The UV-vis absorption, photoluminescence, and electrochemical properties of these chromophores can be dramatically affected by the isomeric linkage of the SO unit, and the alkylfluorene unit that was incorporated between the SO unit and N-atoms in the 4-(9H-carbazole-9-yl)aniline moiety. The resulting chromophores exhibited moderate electroluminescence properties. The best device performance is attained based on compound M-3, which exhibited a peak luminous efficiency of 5.6 cd A−1 and a luminescence of 16 390 cd m−2 with a turn on voltage of 2.4 V and CIE coordinates of (0.31, 0.58). These results indicated that bipolar architectures can be a promising molecular design strategy for the synthesis of organic semiconductors with efficient light emission.",
        "keywords": "",
        "authors": [
            {
                "name": "Sen Zhao",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, State Key Laboratory of Luminescent Materials and Devices, South China University of Technology,Guangzhou 510640,China"
            },
            {
                "name": "Yuan Xie",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, State Key Laboratory of Luminescent Materials and Devices, South China University of Technology,Guangzhou 510640,China"
            },
            {
                "name": "Junfei Liang",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, State Key Laboratory of Luminescent Materials and Devices, South China University of Technology,Guangzhou 510640,China"
            },
            {
                "name": "Ting Guo",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, State Key Laboratory of Luminescent Materials and Devices, South China University of Technology,Guangzhou 510640,China"
            },
            {
                "name": "Lei Ying",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, State Key Laboratory of Luminescent Materials and Devices, South China University of Technology,Guangzhou 510640,China"
            },
            {
                "name": "Hongbin Wu",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, State Key Laboratory of Luminescent Materials and Devices, South China University of Technology,Guangzhou 510640,China"
            },
            {
                "name": "Wei Yang",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, State Key Laboratory of Luminescent Materials and Devices, South China University of Technology,Guangzhou 510640,China"
            },
            {
                "name": "Junbiao Peng",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, State Key Laboratory of Luminescent Materials and Devices, South China University of Technology,Guangzhou 510640,China"
            },
            {
                "name": "Yong Cao",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, State Key Laboratory of Luminescent Materials and Devices, South China University of Technology,Guangzhou 510640,China"
            }
        ],
        "venue": "New Journal of Chemistry",
        "year": 2016
    },
    "l3uv7AtZ": {
        "id": "l3uv7AtZ",
        "title": "Formation of poly(9,9-dioctylfluorene) β-phase by incorporating aromatic moiety in side chain",
        "abstract": "Abstract   Two novel polyfluorene-based blue-light emitting copolymers consisting of aromatic carbazole or dibenzothiophene- S , S -dioxide (SO) moiety in side chain are designed and synthesized based on a palladium-catalyzed Suzuki polymerization. The UV–vis absorption, photoluminescence characteristics and wide-angle X-ray diffraction measurements of the resulting copolymers demonstrate that the incorporation of such aromatic units can induce the formation of the  β -phase. The resulting copolymers consisting of aromatic units exhibit improved electroluminescence properties relative to the pristine PFO film. A maximum luminous efficiency of 2.25 cd A −1  with Commission Internationale de l’Eclairage coordinates of (0.17, 0.09) is obtained from the light-emitting device based on the copolymer consisting of SO unit (PFO-SO). Device based on copolymer PFO-SO also exhibits stable electroluminescent spectra and relatively low roll-off of luminous efficiency at high current densities. These observations indicate that the incorporation of aromatic moiety in side chain is a promising strategy to obtain stable blue-light-emitting polyfluorenes with enhanced efficiency.",
        "keywords": "",
        "authors": [
            {
                "name": "Sen Zhao",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, State Key Laboratory of Luminescent Materials and Devices, South China of University of Technology, Guangzhou 510640, China"
            },
            {
                "name": "Junfei Liang",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, State Key Laboratory of Luminescent Materials and Devices, South China of University of Technology, Guangzhou 510640, China"
            },
            {
                "name": "Ting Guo",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, State Key Laboratory of Luminescent Materials and Devices, South China of University of Technology, Guangzhou 510640, China"
            },
            {
                "name": "Yu Wang",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, State Key Laboratory of Luminescent Materials and Devices, South China of University of Technology, Guangzhou 510640, China"
            },
            {
                "name": "Xuan Chen",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, State Key Laboratory of Luminescent Materials and Devices, South China of University of Technology, Guangzhou 510640, China"
            },
            {
                "name": "Denghao Fu",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, State Key Laboratory of Luminescent Materials and Devices, South China of University of Technology, Guangzhou 510640, China"
            },
            {
                "name": "Junbin Xiong",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, State Key Laboratory of Luminescent Materials and Devices, South China of University of Technology, Guangzhou 510640, China"
            },
            {
                "name": "Lei Ying",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, State Key Laboratory of Luminescent Materials and Devices, South China of University of Technology, Guangzhou 510640, China"
            },
            {
                "name": "Wei Yang",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, State Key Laboratory of Luminescent Materials and Devices, South China of University of Technology, Guangzhou 510640, China"
            },
            {
                "name": "Junbiao Peng",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, State Key Laboratory of Luminescent Materials and Devices, South China of University of Technology, Guangzhou 510640, China"
            },
            {
                "name": "Yong Cao",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, State Key Laboratory of Luminescent Materials and Devices, South China of University of Technology, Guangzhou 510640, China"
            }
        ],
        "venue": "Organic Electronics",
        "year": 2016
    },
    "JG3lTZpA": {
        "id": "JG3lTZpA",
        "title": "Effect of Monofluoro Substitution on the Optoelectronic Properties of Benzo[c][1,2,5]thiadiazole Based Organic Semiconductors",
        "abstract": "The effects of fluorine substitutions on the molecular geometry and optoelectronic properties were investigated based on the conjugated molecular framework consisting of the mono-fluorinated benzo[c][1,2,5]thiadiazole unit. The two-dimensional nuclear magnetic resonance spectroscopy of model compounds indicated that the fluorine substitution can significantly change the chemical environment of the adjacent hydrogen atoms, which was in consistence with the changed molecular geometry as indicated by single crystal diffractions and theoretical calculations. Based on an AB type of monomer, the regioregular conjugated polymer with specifically oriented fluorine along the vector of the polymer backbone was constructed. The UV–vis absorption, photoluminescent, and electroluminescent spectra demonstrated the slightly hypsochromic shift of the copolymer comprising the fluorine substitution relative to the non-fluorinated counterpart. Of particular interest is that the copolymer based on the fluorinated benzothiadi...",
        "keywords": "",
        "authors": [
            {
                "name": "Wenkai Zhong",
                "org": ""
            },
            {
                "name": "Junfei Liang",
                "org": ""
            },
            {
                "name": "Shuzhi Hu",
                "org": ""
            },
            {
                "name": "Xiao-Fang Jiang",
                "org": ""
            },
            {
                "name": "Lei Ying",
                "org": ""
            },
            {
                "name": "Fei Huang",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Yong Cao",
                "org": ""
            }
        ],
        "venue": "Macromolecules",
        "year": 2016
    },
    "7YhIJJMo": {
        "id": "7YhIJJMo",
        "title": "High Molecular Weight Broad Band-Gap Polymers Based on Indolo[3,2-b]carbazole and Thiazolo[5,4-d]thiazole Derivatives for Solar Cells",
        "abstract": "Two broad band-gap high molecular weight polymers, poly[(5,11-di(9'-heptadecanyl)-indolo[3,2-b]carbazole-alt-2,5-bis(3-n-octylthiophene-2-yl)-thiazolo[5,4-d]thiazole (PICzOTzTz) and poly[(5,11-di(9'-heptadecanyl)-indolo[3,2-b]carbazole-alt-2,5-bis(3-n-n-dodecylthiophene-2-yl)-thiazolo[5,4-d]thiazole]) (PICzDOTzTz), consisting of indolo[3,2-b]carbazole (ICz) and thiazolo[5,4-d]thiazole (TzTz) derivatives were synthesized by Suzuki polycondensation. Their physical, electrochemical and optical properties were characterized in details. The thermogravimetric analysis displayed high thermal stability, and 5% degradation temperatures of PICzOTzTz and PICzDOTzTz were 427 and 435A degrees C, respectively. The optical band gaps of PICzOTzTz and PICzDOTzTz were 2.13 and 2.07 eV, respectively. The hole mobilities of PICzOTzTz and PICzDOTzTz were investigated by the space charge limited current (SCLC) method, which gave the mobility values of 7.21 x 10(-5) and 1.57 x 10(-4) cm(2)/(V s) for each polymer, respectively. Through the photo-voltaic characterization in polymer solar cells, they showed that the power conversion efficiencies of PICzOTzTz and PICzDOTzTz were 0.64 and 0.99%, respectively.",
        "keywords": [
            "FIELD-EFFECT TRANSISTORS",
            "THIN-FILM TRANSISTORS",
            "PHOTOVOLTAIC CELLS",
            "OPTOELECTRONIC MATERIALS",
            "CONVERSION EFFICIENCY",
            "PERFORMANCE",
            "INDOLOCARBAZOLE",
            "COPOLYMERS",
            "MORPHOLOGY",
            "CARBAZOLE"
        ],
        "authors": [
            {
                "name": "Zhong, Wenkai",
                "org": "South China Univ Technol, Inst Polymer Optoelect Mat &amp; Devices, State Key Lab Luminescent Mat &amp; Devices, Guangzhou 510640, Guangdong, Peoples R China."
            },
            {
                "name": "Xu, Chao",
                "org": "South China Univ Technol, Inst Polymer Optoelect Mat &amp; Devices, State Key Lab Luminescent Mat &amp; Devices, Guangzhou 510640, Guangdong, Peoples R China."
            },
            {
                "name": "Xiao, Biao",
                "org": "South China Univ Technol, Inst Polymer Optoelect Mat &amp; Devices, State Key Lab Luminescent Mat &amp; Devices, Guangzhou 510640, Guangdong, Peoples R China."
            },
            {
                "name": "Fan, Li",
                "org": "South China Univ Technol, Inst Polymer Optoelect Mat &amp; Devices, State Key Lab Luminescent Mat &amp; Devices, Guangzhou 510640, Guangdong, Peoples R China."
            },
            {
                "name": "Wu, Hongbin",
                "org": "South China Univ Technol, Inst Polymer Optoelect Mat &amp; Devices, State Key Lab Luminescent Mat &amp; Devices, Guangzhou 510640, Guangdong, Peoples R China."
            },
            {
                "name": "Zhang, Bin",
                "org": "Shenzhen Univ, Coll Optoelect Engn, Key Lab Optoelect Devices &amp; Syst, Minist Educ &amp; Guangdong Prov, Shenzhen 518060, Peoples R China."
            },
            {
                "name": "Yang, Wei",
                "org": "South China Univ Technol, Inst Polymer Optoelect Mat &amp; Devices, State Key Lab Luminescent Mat &amp; Devices, Guangzhou 510640, Guangdong, Peoples R China."
            }
        ],
        "venue": "POLYMER SCIENCE SERIES B",
        "year": 2016
    },
    "T8lH9JNv": {
        "id": "T8lH9JNv",
        "title": "Wide bandgap dithienobenzodithiophene-based π-conjugated polymers consisting of fluorinated benzotriazole and benzothiadiazole for polymer solar cells",
        "abstract": "Two wide bandgap donor–acceptor type π-conjugated polymers based on dithienobenzodithiophene as the donor unit and difluorobenzotriazole or difluorobenzothiadiazole as the acceptor unit were designed and synthesized. The copolymer based on difluorobenzothiadiazole exhibited more pronounced aggregations in chlorobenzene solutions than that of the copolymer based on difluorobenzotriazole. Both copolymers exhibited relatively wide bandgaps with deep highest occupied molecular orbitals, leading to high open circuit voltages of over 0.95 V for the fabricated polymer solar cells. These copolymers exhibited quite analogous hole mobility of about 0.1 cm2 V−1 s−1 as measured by organic field effect transistors. Bulk heterojunction polymer solar cells based on these copolymers as the electron-donating materials and PC71BM as the electron-accepting material exhibited relatively high performance, with the best power conversion efficiency of 7.45% attained for the copolymer based on the difluorobenzothiadiazole unit. These results demonstrated that the constructed wide bandgap π-conjugated polymers can be promising candidates for the fabrication of high performance solar cells with multi-junction architectures.",
        "keywords": "",
        "authors": [
            {
                "name": "Wenkai Zhong",
                "org": "State Key Laboratory of Luminescent Materials and Devices, and Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology,Guangzhou 510640,China"
            },
            {
                "name": "Jingyang Xiao",
                "org": "State Key Laboratory of Luminescent Materials and Devices, and Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology,Guangzhou 510640,China"
            },
            {
                "name": "Sheng Sun",
                "org": "State Key Laboratory of Luminescent Materials and Devices, and Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology,Guangzhou 510640,China"
            },
            {
                "name": "Xiao-Fang Jiang",
                "org": "State Key Laboratory of Luminescent Materials and Devices, and Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology,Guangzhou 510640,China"
            },
            {
                "name": "Linfeng Lan",
                "org": "State Key Laboratory of Luminescent Materials and Devices, and Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology,Guangzhou 510640,China"
            },
            {
                "name": "Lei Ying",
                "org": "State Key Laboratory of Luminescent Materials and Devices, and Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology,Guangzhou 510640,China"
            },
            {
                "name": "Wei Yang",
                "org": "State Key Laboratory of Luminescent Materials and Devices, and Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology,Guangzhou 510640,China"
            },
            {
                "name": "Hin-Lap Yip",
                "org": "State Key Laboratory of Luminescent Materials and Devices, and Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology,Guangzhou 510640,China"
            },
            {
                "name": "Fei Huang",
                "org": "State Key Laboratory of Luminescent Materials and Devices, and Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology,Guangzhou 510640,China"
            },
            {
                "name": "Yong Cao",
                "org": "State Key Laboratory of Luminescent Materials and Devices, and Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology,Guangzhou 510640,China"
            }
        ],
        "venue": "Journal of Materials Chemistry C",
        "year": 2016
    },
    "N6QitAxm": {
        "id": "N6QitAxm",
        "title": "Effects of pyridyl group orientations on the optoelectronic properties of regio-isomeric diketopyrrolopyrrole based π-conjugated polymers",
        "abstract": "Two novel regio-isomeric π-conjugated polymers consisting of the pyridyl unit flanked by diketopyrrolopyrrole as the electron-accepting unit and 2,5-bis(3-hexylthiophen-2-yl)thieno[3,2-b]thiophene as the electron-donating unit were designed and synthesized. The comparison of the optical and electrochemical properties indicated that the copolymer based on the nitrogen atom proximal to the central diketopyrrolopyrrole unit (p-PDBPy) exhibited bathochromic shifted absorption spectra and narrower bandgaps than the counterpart copolymer (d-PDBPy) with the distally oriented nitrogen atom, which can be correlated with the stronger intermolecular aggregation of the former as a result of the different intrinsic molecular geometry of the polymer backbone. Of particular interest is that the copolymer p-PDBPy exhibited a moderate hole mobility of 0.35 cm2 V−1 s−1, which is about three orders of magnitude higher than the hole mobility of 3.2 × 10−4 cm2 V−1 s−1 obtained based on the counterpart copolymer d-PDBPy, as measured using organic field-effect transistors. These results demonstrated that the delicate control of the pyridyl orientations along the polymer backbone is of vital importance for the molecular design of π-conjugated polymers for high-performance organic electronic devices.",
        "keywords": "",
        "authors": [
            {
                "name": "Jing Yue",
                "org": "State Key Laboratory of Luminescent Materials and Devices, and Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology,Guangzhou 510640,China"
            },
            {
                "name": "Sheng Sun",
                "org": "State Key Laboratory of Luminescent Materials and Devices, and Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology,Guangzhou 510640,China"
            },
            {
                "name": "Junfei Liang",
                "org": "State Key Laboratory of Luminescent Materials and Devices, and Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology,Guangzhou 510640,China"
            },
            {
                "name": "Wenkai Zhong",
                "org": "State Key Laboratory of Luminescent Materials and Devices, and Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology,Guangzhou 510640,China"
            },
            {
                "name": "Linfeng Lan",
                "org": "State Key Laboratory of Luminescent Materials and Devices, and Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology,Guangzhou 510640,China"
            },
            {
                "name": "Lei Ying",
                "org": "State Key Laboratory of Luminescent Materials and Devices, and Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology,Guangzhou 510640,China"
            },
            {
                "name": "Fei Huang",
                "org": "State Key Laboratory of Luminescent Materials and Devices, and Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology,Guangzhou 510640,China"
            },
            {
                "name": "Wei Yang",
                "org": "State Key Laboratory of Luminescent Materials and Devices, and Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology,Guangzhou 510640,China"
            },
            {
                "name": "Yong Cao",
                "org": "State Key Laboratory of Luminescent Materials and Devices, and Institute of Polymer Optoelectronic Materials and Devices, South China University of Technology,Guangzhou 510640,China"
            }
        ],
        "venue": "Journal of Materials Chemistry C",
        "year": 2016
    },
    "5fEAX8oz": {
        "id": "5fEAX8oz",
        "title": "Blue light-emitting polymers containing fluorene-based benzothiophene-S,S-dioxide derivative",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "wei yang",
                "org": ""
            },
            {
                "name": "liwen hu",
                "org": ""
            },
            {
                "name": "yong yang",
                "org": ""
            },
            {
                "name": "xu jin",
                "org": ""
            },
            {
                "name": "junfei liang",
                "org": ""
            },
            {
                "name": "ting guo",
                "org": ""
            },
            {
                "name": "bin zhang",
                "org": ""
            },
            {
                "name": "yong cao",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2016
    },
    "ETI4OZ2l": {
        "id": "ETI4OZ2l",
        "title": "Deep carbon cycles constrained by a large-scale mantle Mg isotope anomaly in eastern China",
        "abstract": "Although deep carbon recycling plays an important role in the atmospheric CO 2  budget and climate changes through geological time, the precise mechanisms remain poorly understood. Since recycled sedimentary carbonate through plate subduction is the main light-δ 26 Mg reservoir within deep-Earth, Mg isotope variation in mantle-derived melts provides a novel perspective when investigating deep carbon cycling. Here, we show that the Late Cretaceous and Cenozoic continental basalts from 13 regions covering the whole of eastern China have low δ 26 Mg isotopic compositions, while the Early Cretaceous basalts from the same area and the island arc basalts from circum-Pacific subduction zones have mantle-like or heavy Mg isotopic characteristics. Thus, a large-scale mantle low δ 26 Mg anomaly in eastern China has been delineated, suggesting the contribution of sedimentary carbonates recycled into the upper mantle, but limited into the lower mantle. This large-scale spatial and temporal variation of Mg isotopes in the mantle places severe constraints on deep carbon recycling via oceanic subduction.",
        "keywords": "",
        "authors": [
            {
                "name": "Shuguang Li",
                "org": "State Key Laboratory of Geological Processes and Mineral Resources, China University of Geosciences, Beijing 100083, China;"
            },
            {
                "name": "Shuguang Li",
                "org": "State Key Laboratory of Geological Processes and Mineral Resources, China University of Geosciences, Beijing 100083, China;"
            },
            {
                "name": "Wei Yang",
                "org": "Key Laboratory of Earth and Planetary Physics, Institute of Geology and Geophysics, Chinese Academy of Sciences, Beijing 100029, China;"
            },
            {
                "name": "Shan Ke",
                "org": "State Key Laboratory of Geological Processes and Mineral Resources, China University of Geosciences, Beijing 100083, China;"
            },
            {
                "name": "Xunan Meng",
                "org": "State Key Laboratory of Geological Processes and Mineral Resources, China University of Geosciences, Beijing 100083, China;"
            },
            {
                "name": "Heng-Ci Tian",
                "org": "Key Laboratory of Earth and Planetary Physics, Institute of Geology and Geophysics, Chinese Academy of Sciences, Beijing 100029, China;"
            },
            {
                "name": "Lijuan Xu",
                "org": "State Key Laboratory of Geological Processes and Mineral Resources, China University of Geosciences, Beijing 100083, China;"
            },
            {
                "name": "Yongsheng He",
                "org": "State Key Laboratory of Geological Processes and Mineral Resources, China University of Geosciences, Beijing 100083, China;"
            },
            {
                "name": "Jian Huang",
                "org": "CAS Key Laboratory of Crust-Mantle Materials and Environments, School of Earth and Space Sciences, University of Science and Technology of China, Hefei 230026, China;"
            },
            {
                "name": "Xuan-Ce Wang",
                "org": "The Institute for Geoscience Research, Department of Applied Geology, Curtin University, Perth, WA 6845, Australia;"
            },
            {
                "name": "Qunke Xia",
                "org": "School of Earth Sciences, Zhejiang University, Hangzhou 310027, China;"
            },
            {
                "name": "Weidong Sun",
                "org": "Key Laboratory of Mineralogy and Metallogeny, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou 510640, China;"
            },
            {
                "name": "Xiaoyong Yang",
                "org": "CAS Key Laboratory of Crust-Mantle Materials and Environments, School of Earth and Space Sciences, University of Science and Technology of China, Hefei 230026, China;"
            },
            {
                "name": "Zhong-Yuan Ren",
                "org": "Key Laboratory of Mineralogy and Metallogeny, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou 510640, China;"
            },
            {
                "name": "Haiquan Wei",
                "org": "Institute of Geology, China Earthquake Administration, Beijing 100029, China;"
            },
            {
                "name": "Yongsheng Liu",
                "org": "State Key Laboratory of Geological Processes and Mineral Resources, Faculty of Earth Sciences, China University of Geosciences, Wuhan 430074, China;"
            },
            {
                "name": "Fancong Meng",
                "org": "Institute of Geology, Chinese Academy of Geological Sciences, Beijing 100037, China;"
            },
            {
                "name": "Jun Yan",
                "org": "School of Resources and Environmental Engineering, Hefei University of Technology, Hefei 230009, China."
            }
        ],
        "venue": "National Science Review",
        "year": 2016
    },
    "ecOyStPR": {
        "id": "ecOyStPR",
        "title": "Improving efficiency and color purity of poly(9,9-dioctylfluorene) through addition of a high boiling-point solvent of 1-chloronaphthalene.",
        "abstract": "In this work, the β-phase of poly(9,9-dioctylfluorene) (PFO) was used as a probe to study the effects of the addition of a high boiling-point solvent of 1-chloronaphthalene on the nanostructures and electroluminescence of PFO films. Both absorption and photoluminescence spectra showed that the content of the β-phase in PFO film was obviously enhanced as a result of the addition of a small amount of 1-chloronaphthalene into the processing solvent of p-xylenes. Apparently rougher morphology associated with the effectively enhanced ordering of polymer chains across the entire film was observed for films processed from p-xylene solutions consisting of a certain amount of 1-chloronaphthalene, as revealed by atomic force microscopy and grazing incidence x-ray diffraction measurements. In addition to the effects on the nanostructures of films, of particular interest is that the performance and color purity of polymer light-emitting devices can be noticeably enhanced upon the addition of 1-chloronaphthalene. These observations highlight the importance of controlling the nanostructures of the emissive layer, and demonstrate that the addition of a low volume ratio of high boiling-point additive can be a promising strategy to attain high-performance polymer light-emitting diodes. ",
        "keywords": "",
        "authors": [
            {
                "name": "Junfei Liang",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, State Key Lab of Luminescent Materials and Devices, South China University of Technology, Guangzhou 510640, People's Republic of China."
            },
            {
                "name": "Lei Yu",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, State Key Lab of Luminescent Materials and Devices, South China University of Technology, Guangzhou 510640, People’s Republic of China"
            },
            {
                "name": "Sen Zhao",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, State Key Lab of Luminescent Materials and Devices, South China University of Technology, Guangzhou 510640, People’s Republic of China"
            },
            {
                "name": "Lei Ying",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, State Key Lab of Luminescent Materials and Devices, South China University of Technology, Guangzhou 510640, People’s Republic of China"
            },
            {
                "name": "Feng Liu",
                "org": "Department of Polymer Science and Engineering, University of Massachusetts Amherst, Massachusetts 01003, USA"
            },
            {
                "name": "Wei Yang",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, State Key Lab of Luminescent Materials and Devices, South China University of Technology, Guangzhou 510640, People’s Republic of China"
            },
            {
                "name": "Junbiao Peng",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, State Key Lab of Luminescent Materials and Devices, South China University of Technology, Guangzhou 510640, People’s Republic of China"
            },
            {
                "name": "Yong Cao",
                "org": "Institute of Polymer Optoelectronic Materials and Devices, State Key Lab of Luminescent Materials and Devices, South China University of Technology, Guangzhou 510640, People’s Republic of China"
            }
        ],
        "venue": "Nanotechnology",
        "year": 2016
    },
    "DwxGjVEs": {
        "id": "DwxGjVEs",
        "title": "White Polymer Light-Emitting Diodes Based on Exciplex Electroluminescence from Polymer Blends and a Single Polymer",
        "abstract": "In this Article, we designed and synthesized a series of polyfluorene derivatives, which consist of the electron-rich 4,4′-(9-alkyl-carbazole-3,6-diyl)bis(N,N-diphenylaniline) (TPA-Cz) in the side chain and the electron-deficient dibenzothiophene-5,5-dioxide (SO) unit in the main chain. The resulting copolymer PF-T25 that did not comprise the SO unit exhibited blue light-emission with the Commission Internationale de L’Eclairage coordinates of (0.16, 0.10). However, by physically blending PF-T25 with a blue light-emitting SO-based oligomer, a novel low-energy emission correlated to exciplex emerged due to the appropriate energy level alignment of TPA-Cz and the SO-based oligomers, which showed extended exciton lifetime as confirmed by time-resolved photoluminescent spectroscopy. The low-energy emission was also identified in copolymers consisting of SO unit in the main chain, which can effectively compensate for the high-energy emission to produce binary white light-emission. Polymer light-emitting diodes...",
        "keywords": "",
        "authors": [
            {
                "name": "Junfei Liang",
                "org": ""
            },
            {
                "name": "Sen Zhao",
                "org": ""
            },
            {
                "name": "Xiao-Fang Jiang",
                "org": ""
            },
            {
                "name": "Ting Guo",
                "org": ""
            },
            {
                "name": "Hin-Lap Yip",
                "org": ""
            },
            {
                "name": "Lei Ying",
                "org": ""
            },
            {
                "name": "Fei Huang",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Yong Cao",
                "org": ""
            }
        ],
        "venue": "ACS Applied Materials & Interfaces",
        "year": 2016
    },
    "3aOrYDHz": {
        "id": "3aOrYDHz",
        "title": "Side chain effect on photovoltaic properties of dibenzo[a,c]phenazine based donor–acceptor polymers",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "feng peng",
                "org": ""
            },
            {
                "name": "baofeng zhao",
                "org": ""
            },
            {
                "name": "jin xu",
                "org": ""
            },
            {
                "name": "yuhao zhang",
                "org": ""
            },
            {
                "name": "yiwen fang",
                "org": ""
            },
            {
                "name": "ruifeng he",
                "org": ""
            },
            {
                "name": "hongbin wu",
                "org": ""
            },
            {
                "name": "wei yang",
                "org": ""
            },
            {
                "name": "yong cao",
                "org": ""
            }
        ],
        "venue": "Organic Electronics",
        "year": 2016
    },
    "Gj2mvN8b": {
        "id": "Gj2mvN8b",
        "title": "Maternal periconceptional alcohol consumption and risk for conotruncal heart defects.",
        "abstract": "In this study we investigated whether the risk of delivering infants with conotruncal heart defects was increased among mothers who consumed alcohol during the periconceptional period (i.e., 1 month before conception to 3 months after conception).Data were obtained from a population-based case-control study of California births from 1987-1988. Information concerning alcohol consumption was obtained via telephone interviews with mothers of 207 (87% of eligibles) case infants and 481 (76%) nonmalformed control infants.Bivariate results indicated that relative to nonconsumers, women who consumed alcohol less than once a week had a 1.3-fold increased risk of delivering infants with a conotruncal heart defect (95% confidence interval (CI) 1.0, 1.9), and women who consumed alcohol once a week or more had a 1.9-fold increased risk (95% CI 1.0, 3.4). The risks associated with consuming five or more drinks per drinking occasion were 1.6 (95% CI 0.8, 3.2) for less than once a week, and 2.4 for once a week or more (95% CI 0.6, 9.7). The results for the phenotypic subgroups were similar to those for all cases. Adjustment for potential covariates resulted in somewhat weaker, but still elevated, risks.This study found that the risk of conotruncal heart defects in offspring was moderately elevated among women who consumed alcoholic beverages during the periconceptional period, and that risk was higher with increased frequency of drinking or increased number of drinks consumed per occasion. Most of the risk estimates were imprecise, and chance could not be ruled out as an explanation for the observed findings.",
        "keywords": [
            "teratogens"
        ],
        "authors": [
            {
                "name": "Suzan L. Carmichael",
                "org": "March of Dimes Birth Defects Foundation/California Department of Health Services, California Birth Defects Monitoring Program, Oakland, California, USA."
            },
            {
                "name": "Gary M. Shaw",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Edward J. Lammer",
                "org": ""
            }
        ],
        "venue": "Birth defects research. Part A, Clinical and molecular teratology",
        "year": 2003
    },
    "VuQhHB1j": {
        "id": "VuQhHB1j",
        "title": "Genetic Variation of Infant Reduced Folate Carrier (A80G) and Risk of Orofacial and Conotruncal Heart Defects",
        "abstract": "How folate reduces the risks of congenital anomalies is unknown. The authors focused on a gene involved in folate transport—reduced folate carrier-1 gene (RFC1). Using data from a California case-control study (1987- 1989 births), the authors investigated whether the risks of orofacial clefts or conotruncal heart defects were influenced by a polymorphism of infant RFC1 or by an interaction between the RFC1 gene and maternal periconceptional use of vitamins containing folic acid. A total of 305 liveborn infants with cleft lip with or without cleft palate, 123 with cleft palate, 163 with conotruncal heart defects, and 364 nonmalformed controls were genotyped. Odds ratios of 1.6 (95% confidence interval: 0.9, 2.8) for the G80/G80 genotype and of 2.3 (95% confidence interval: 1.3, 3.9) for the G80/A80 genotype were observed relative to the A80/A80 genotype for conotruncal defects. Among mothers who did not use vitamins, the risk of conotruncal defects was 2.1 (95% confidence interval: 0.7, 5.9) for infants with genotype G80/G80 compared with those with the A80/A80 genotype. Among mothers who did use vitamins, the risk was 1.3 (95% confidence interval: 0.7, 2.7). Substantially elevated risks for either cleft group were not observed irrespective of genotype and use/nonuse of vitamins. Thus, this study found modest evidence for a gene-nutrient interaction between infant RFC1 genotype and periconceptional intake of vitamins on the risk of conotruncal defects. abnormalities; case-control studies; cleft lip; cleft palate; folic acid; heart defects, congenital",
        "keywords": [],
        "authors": [
            {
                "name": "Gary M. Shaw",
                "org": "March"
            },
            {
                "name": "Huiping Zhu",
                "org": "Institute of Biosciences and Technology|Texas A&M University System Health Science Center"
            },
            {
                "name": "Edward J. Lammer",
                "org": "Division of Medical Genetics|Children ' s Hospital"
            },
            {
                "name": "Wei Yang",
                "org": "March"
            },
            {
                "name": "Richard H. Finnell",
                "org": "Institute of Biosciences and Technology|Texas A&M University System Health Science Center"
            }
        ],
        "venue": "American journal of epidemiology",
        "year": 2003
    },
    "7VuKHlK2": {
        "id": "7VuKHlK2",
        "title": "Limb deficiency defects, MSX1, and exposure to tobacco smoke.",
        "abstract": "There is increasing evidence from epidemiologic studies that genetic susceptibilities may modify the teratogenic effects of smoking. A previous study suggested that maternal smoking in the presence of a dinucleotide repeat polymorphism for MSX1 produced an almost fivefold increased risk for limb anomalies, providing evidence for a gene-environment interaction. The current study examined this potential interaction, using case-control data with several methodologic improvements, including a larger sample size and more detailed information on cigarette smoke exposures. Cases (n = 92) were ascertained from pregnancies ending in 1987-1989, and controls (n = 180) were randomly selected from eligible liveborn infants. In telephone interviews, women reported smoking behaviors during the month before pregnancy through the end of the first trimester. Odds ratios (OR) for maternal and paternal smoking ranged from 1.0 to 1.4, risk estimates were imprecise; for example, the OR for maternal smoking >or=20 cigarettes per day, versus none, was 1.3 (95% confidence interval (CI) 0.5-3.4). Relative to the homozygous wildtype, the OR was 1.5 (95% CI 0.7-3.5) for the homozygous variant genotype and 0.8 (95% CI 0.5-1.4) for the heterozygous variant genotype. There was no evidence that maternal smoking or both parents smoking, in combination with a susceptible MSX1 genotype, conferred an additional increase in risk of limb defects. This study did not find a gene-environment interaction between maternal smoking, infant MSX1 CA repeat polymorphism, and risk of limb deficiency defects. This finding contrasts with results of a previous study, which provided initial evidence for such an interaction. Several important methodological differences may have contributed to the differences in findings between the two studies.",
        "keywords": [
            "homeobox genes"
        ],
        "authors": [
            {
                "name": "Suzan L. Carmichael",
                "org": "March of Dimes Birth Defect Foundation/California Department of Health Services, California Birth Defects Monitoring Program, Oakland, California 94710, USA. sca@cbdmp.org"
            },
            {
                "name": "Gary M. Shaw",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Edward J. Lammer",
                "org": ""
            },
            {
                "name": "Huiping Zhu",
                "org": ""
            },
            {
                "name": "Richard H. Finnell",
                "org": ""
            }
        ],
        "venue": "American journal of medical genetics. Part A",
        "year": 2004
    },
    "y9b35h6W": {
        "id": "y9b35h6W",
        "title": "Congenital malformations in births with orofacial clefts among 3.6 million California births, 1983-1997.",
        "abstract": "Few population-based epidemiologic data are available on malformation phenotypes that co-occur with orofacial clefts. We explored the occurrence of structural congenital malformations in offspring with cleft palate (CP) and in offspring with cleft lip with or without CP (CLP), using data from a population-based active surveillance system. Ascertainment was performed among 3548991 liveborn and 23239 stillborn offspring of California women who delivered in nonmilitary hospitals during the period, 1983-1997. Structural congenital malformations were found in 91888 births. Among them, 2343 had CP and 4072 had CLP. Malformations were grouped according to 3- and 4-digit codes of the British Pediatric Association (BPA). Prevalences of each malformation grouping, defined by these codes, were calculated among: (1). all births with CP; (2). all births with CLP; (3). all births without CP or CLP but with another structural malformation; and (4). all births in the population at risk. These various prevalence measures were the basis of estimating relative risks. Observed relative risks indicated that some phenotypes were more likely and some were less likely to co-occur with either CP or CLP, with relative risks ranging from 0.5 to 2.4. For both CP and CLP, estimated relative risks were highest for malformations involving the respiratory system and lowest for spina bifida. The exclusion of all births (n = 10702) with chromosomal anomalies from comparisons did not materially alter observed relative risk estimates. Computations extended to 4-digit level BPA codes revealed elevated risks for a number of more specific diagnoses seen within the larger (3-digit level) groupings defined as eye, ear, respiratory, upper alimentary tract, and other musculoskeletal anomalies. In this large population-based cohort of infants and fetuses with CLP or CP, we observed several noncleft malformation groupings to be more common and others to be less common in their co-occurrence with orofacial clefts relative to their co-occurrence with any other malformation. These observed patterns tended to be similar for CP and for CLP.",
        "keywords": [
            "prevalence",
            "epidemiology"
        ],
        "authors": [
            {
                "name": "Gary M. Shaw",
                "org": "March of Dimes Birth Defects Foundation, California Birth Defects Monitoring Program, Oakland, California 94710, USA. gsh@cbdmp.org"
            },
            {
                "name": "Suzan L. Carmichael",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "John A. Harris",
                "org": ""
            },
            {
                "name": "Edward J. Lammer",
                "org": ""
            }
        ],
        "venue": "American journal of medical genetics. Part A",
        "year": 2004
    },
    "PtmlWOzE": {
        "id": "PtmlWOzE",
        "title": "Endothelial nitric oxide synthase (NOS3) genetic variants, maternal smoking, vitamin use, and risk of human orofacial clefts.",
        "abstract": "Orofacial clefts have been associated with maternal cigarette smoking and lack of folic acid supplementation (which results in higher plasma homocysteine concentrations). Because endothelial nitric oxide synthase (NOS3) activity influences homocysteine concentration and because smoking compromises NOS3 activity, genetic variation in NOS3 might interact with smoking and folic acid use in clefting risk. The authors genotyped 244 infants with isolated cleft lip with or without cleft palate (CL/P), 99 with isolated cleft palate, and 588 controls from a California population-based case-control study (1987-1989 birth cohort) for two NOS3 polymorphisms: A(-922)G and G894T. Analyses of gene-only effects for each polymorphism revealed a 60% increased risk of CL/P among NOS3 A(-922)G homozygotes (odds ratio (OR) = 1.6, 95% confidence interval (CI): 1.0, 2.6). There was some evidence for higher risk of CL/P with maternal periconceptional smoking in infants with an NOS3 -922G allele (for homozygotes, OR = 2.5, 95% CI: 1.2, 5.6) but not in those with an 894T allele. For CL/P risk, odds ratios were over 4 among mothers who smoked, who did not use vitamins, and whose infants had at least one variant allele for each NOS3 polymorphism (for A(-922)G, OR = 4.6, 95% CI: 2.1, 10.2; for 894T, OR = 4.4, 95% CI: 1.8, 10.7). No similar patterns were observed for risk of cleft palate.",
        "keywords": [],
        "authors": [
            {
                "name": "Gary M. Shaw",
                "org": "California Birth Defects Monitoring Program, March of Dimes Birth Defects Foundation, Berkeley, CA 94710, USA. gsh@cbdmp.org"
            },
            {
                "name": "David M. Iovannisci",
                "org": "Children ' s Hospital Oakland Research Institute"
            },
            {
                "name": "Wei Yang",
                "org": "March of Dimes|Birth Defects Foundation"
            },
            {
                "name": "Richard H. Finnell",
                "org": "Institute of Biosciences and Technology|Texas A&M University|System Health Science Center"
            },
            {
                "name": "Suzan L. Carmichael",
                "org": "March of Dimes|Birth Defects Foundation"
            },
            {
                "name": "Suzanne Cheng",
                "org": "Department of Human Genetics|Roche Molecular Systems , Inc"
            },
            {
                "name": "Edward J. Lammer",
                "org": "Children ' s Hospital Oakland Research Institute"
            }
        ],
        "venue": "American journal of epidemiology",
        "year": 2005
    },
    "SVizlzpk": {
        "id": "SVizlzpk",
        "title": "Are the betaine-homocysteine methyltransferase (BHMT and BHMT2) genes risk factors for spina bifida and orofacial clefts?",
        "abstract": "Abnormalities in folate and/or homocysteine metabolism may adversely influence embryonic development, leading to the birth of infants with a variety of congenital malformations, including neural tube defects (NTDs) and craniofacial abnormalities. Based upon suggestive evidence that periconceptional folic acid supplementation is effective in preventing a significant proportion of the aforementioned birth defects, genetic variation in the folate biosynthetic pathways may influence the infant's susceptibility to these birth defects. The goal of our study was to investigate sequence variations in the betaine-homocysteine methyltransferase (BHMT) and betaine-homocysteine methyltransferase (BHMT2) genes as modifiers of risk of spina bifida, cleft palate, and cleft lip and palate. The results of this study indicated that individuals homozygous for the single nucleotide polymorphism R239Q in BHMT did not have elevated risks for spina bifida. Genotype frequencies for the BHMT2 rs626105 polymorphism also did not reveal any elevated risks for spina bifida, and only a modest, imprecise elevation of risk for orofacial clefts. The results of these experiments suggest that variants of the BHMT/BHMT2 genes in infants do not substantially contribute to the risk of spina bifida or orofacial clefts in our study population.",
        "keywords": [
            "risk factors",
            "gene polymorphism"
        ],
        "authors": [
            {
                "name": "Huiping Zhu",
                "org": "Center for Environmental and Genetic Medicine, Institute of Biosciences and Technology, Texas A and M University System Health Science Center, Houston, Texas 77030, USA."
            },
            {
                "name": "Stacey Curry",
                "org": ""
            },
            {
                "name": "Shu Wen",
                "org": ""
            },
            {
                "name": "Ned J. Wicker",
                "org": ""
            },
            {
                "name": "Gary M. Shaw",
                "org": ""
            },
            {
                "name": "Edward J. Lammer",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Toghrul Jafarov",
                "org": ""
            },
            {
                "name": "Richard H. Finnell",
                "org": ""
            }
        ],
        "venue": "American journal of medical genetics. Part A",
        "year": 2005
    },
    "wFOWnCpv": {
        "id": "wFOWnCpv",
        "title": "Epidemiologic characteristics of anophthalmia and bilateral microphthalmia among 2.5 million births in California, 1989-1997.",
        "abstract": "There is a paucity of epidemiologic information about the eye malformations anophthalmia and microphthalmia. Using data from a large population-based registry, we explored prevalences and maternal/infant characteristics associated with anophthalmia and bilateral microphthalmia. Data were derived from the California Birth Defects Monitoring Program, a population-based active surveillance system for collecting information on infants and fetuses with congenital malformations using multiple source ascertainment. Approximately 2.5 million births (liveborn and stillborn) occurred during the ascertainment period, 1989-1997. Information on maternal and infant/fetal characteristics was obtained from California birth certificate and fetal death files. The prevalence per 10,000 livebirths and stillbirths for anophthalmia was 0.18 and for bilateral microphthalmia was 0.22. These estimates reflect prevalences among births without chromosomal anomalies. Relative risks of anophthalmia were modestly higher among women aged 40 or more (relative risk = 2.0, 95% confidence interval 0.5-8.6). Risks were substantially lower for those mothers with >12 years of education, even after adjusting for other study factors, relative risk = 0.6 (0.2-1.7). The risk of anophthalmia was approximately twofold among multiple births compared to singletons. Similar to results for anophthalmia, decreased risks for bilateral microphthalmia were observed for maternal education of 12 years or more and increased risks observed for multiple births. These data show descriptive epidemiologic features of anophthalmia and bilateral microphthalmia.",
        "keywords": [
            "prevalence",
            "epidemiology"
        ],
        "authors": [
            {
                "name": "Gary M. Shaw",
                "org": "March of Dimes Birth Defects Foundation, California Birth Defects Monitoring Program, Berkeley, USA. gsh@cdbmp.org"
            },
            {
                "name": "Suzan L. Carmichael",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "John A. Harris",
                "org": ""
            },
            {
                "name": "Richard H. Finnell",
                "org": ""
            },
            {
                "name": "Edward J. Lammer",
                "org": ""
            }
        ],
        "venue": "American journal of medical genetics. Part A",
        "year": 2005
    },
    "WBqNj20s": {
        "id": "WBqNj20s",
        "title": "Risks of human conotruncal heart defects associated with 32 single nucleotide polymorphisms of selected cardiovascular disease-related genes.",
        "abstract": "Investigating possible genetic polymorphisms and gene-environment interactions in the etiology of human conotruncal defects is a prudent research approach. In this study we explore gene-only and gene-environment effects of 32 single nucleotide polymorphisms (SNPs) on conotruncal defect risks. The genes bearing these SNPs participate in one of five pathogenetic processes, homocysteine metabolism, coagulation, cell-cell interaction, inflammatory response, and blood pressure regulation. We used DNA samples and data from a California population-based case-control interview study (1987-1988 birth cohort). We employed a multilocus allele-specific hybridization assay. Allelic variants were determined by genotyping 155 infants with conotruncal defects (cases) and 437 infants without malformations (controls). Among the 32 SNPs, four were associated with odds ratios of 2 or more, and two with odds ratios of 0.5 or less. The four SNPs were F2 G20210A (prothrombin) with an odds ratio of 2.5 (95% confidence interval; 0.9-7.0), F7 promoter (-323) 10-bp del/ins with an odds ratio of 2.3 (0.8-6.8), ITGB3 leu33pro (platelet glycoprotein IIIa) with an odds ratio of 2.2 (0.9-5.7), and NPPA T2238C (atrial natriuretic precursor peptide) with an odds ratio of 2.9 (0.8-10.1). Two SNPs were associated with decreased risks: TNF (tumor necrosis factor, G (-376A)) and ADD1 gly460trp (alpha adducin) with odds ratios of 0.5 (0.1-2.3) and 0.5 (0.2-1.9), respectively. Analyses that investigated a potential gene-nutrient interaction between maternal periconceptional vitamin use and MTHFR genotypes did not indicate that the CT or TT genotype contributed to conotruncal defect risk in infants even in the absence of maternal use of multivitamin supplements with folic acid. Analyses that investigated a potential interaction on risk between NOS3 genes and maternal cigarette smoking, revealed some evidence for higher risk of conotruncal defects in infants whose mothers smoked cigarettes periconceptionally and who had one of the variant alleles for NOS3 A(-922G) or NOS3 glu298asp compared to those infants whose mothers did not smoke and whose genotypes were wild-type. Our results provide some support for involvement of genetic variation of biologically relevant candidate genes for some birth defects whose pathogenesis may be related to altered vascular tone or integrity. In particular, NPPA appears to be a good candidate gene for conotruncal defects and warrants further investigation.",
        "keywords": [
            "epidemiology",
            "single nucleotide polymorphism",
            "genes"
        ],
        "authors": [
            {
                "name": "Gary M. Shaw",
                "org": "March of Dimes Birth Defects Foundation, California Birth Defects Monitoring Program, Berkeley 94710, USA. gsh@cbdmp.org"
            },
            {
                "name": "David M. Iovannisci",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Richard H. Finnell",
                "org": ""
            },
            {
                "name": "Suzan L. Carmichael",
                "org": ""
            },
            {
                "name": "Suzanne Cheng",
                "org": ""
            },
            {
                "name": "Edward J. Lammer",
                "org": ""
            }
        ],
        "venue": "American journal of medical genetics. Part A",
        "year": 2005
    },
    "9QuXAEcw": {
        "id": "9QuXAEcw",
        "title": "Periconceptional dietary intake ofmyo-inositol and neural tube defects in offspring",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Gary M. Shaw",
                "org": ""
            },
            {
                "name": "Suzan L. Carmichael",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Donna M. Schaffer",
                "org": ""
            }
        ],
        "venue": "Birth Defects Research Part A-clinical and Molecular Teratology",
        "year": 2005
    },
    "PoJXbfyu": {
        "id": "PoJXbfyu",
        "title": "A known functional polymorphism (Ile120Val) of the human PCMT1 gene and risk of spina bifida.",
        "abstract": "Folate binding protein 1 (Folr1) knockout mice with low maternal folate concentrations have been shown to be excellent animal models for human folate-responsive neural tube defects (NTDs). Previous studies using the Folr1 knockout mice revealed that maternal folate supplementation up-regulates the expression of the PCMT1 gene in Folr1 nullizygous neural tube tissue during neural tube closure. PCMT1 encodes the protein repair enzyme l-isoaspartate (d-aspartate) O-methyltransferase (PIMT) that converts abnormal d-aspartyl and l-isoaspartyl residues to the normal l-aspartyl form. PIMT is known to protect certain neural cells from Bax-induced apoptosis. Pcmt1-deficient mice present with abnormal AdoMet/AdoHcy homeostasis. We hypothesized that a known functional polymorphism (Ile120Val) in the human PCMT1 gene is associated with an increased risk of folate-responsive human NTDs. A case-control study was conducted to investigate a possible association between this polymorphism and risk of spina bifida. Compared to the Ile/Ile and Ile/Val genotypes, the homozygous Val/Val genotype showed decreased risk for spina bifida (adjusted odds ratio=0.6, 95% confidence interval: 0.4-0.9). Our results showed that the Ile120Val polymorphism of PCMT1 gene is a genetic modifier for the risk of spina bifida. Val/Val genotype was associated with a reduction in risk for spina bifida.",
        "keywords": [
            "case control studies",
            "enzyme",
            "polymorphism",
            "gene polymorphism",
            "knockout mice",
            "adjusted odds ratio",
            "l",
            "confidence interval",
            "case control study",
            "cohort studies",
            "risk",
            "genetically modified"
        ],
        "authors": [
            {
                "name": "Huiping Zhu",
                "org": "Center for Environmental and Genetic Medicine, Institute of Biosciences and Technology, Texas A&M University System Health Science Center, Houston, TX 77030, USA"
            },
            {
                "name": "Wei Yang",
                "org": "California Birth Defects Monitoring Program, Berkeley, CA, USA"
            },
            {
                "name": "Wei Lu",
                "org": "Center for Environmental and Genetic Medicine, Institute of Biosciences and Technology, Texas A&M University System Health Science Center, Houston, TX 77030, USA"
            },
            {
                "name": "Jing Zhang",
                "org": "Center for Environmental and Genetic Medicine, Institute of Biosciences and Technology, Texas A&M University System Health Science Center, Houston, TX 77030, USA"
            },
            {
                "name": "Gary M Shaw",
                "org": "California Birth Defects Monitoring Program, Berkeley, CA, USA"
            },
            {
                "name": "Edward J Lammer",
                "org": "Children’s Hospital Oakland Research Institute, Oakland, CA, USA"
            },
            {
                "name": "Richard H Finnell",
                "org": "institute of biosciences and technology"
            }
        ],
        "venue": "Molecular genetics and metabolism",
        "year": 2006
    },
    "smFG2SVz": {
        "id": "smFG2SVz",
        "title": "Risks of human limb deficiency anomalies associated with 29 SNPs of genes involved in homocysteine metabolism, coagulation, cell-cell interactions, inflammatory response, and blood pressure regulation.",
        "abstract": "This study explored risks of limb deficiency anomalies associated with 29 single nucleotide polymorphisms (SNPs) of genes involved in homocysteine metabolism, coagulation, cell-cell interaction, inflammatory response, and blood pressure regulation. The authors genotyped 96 cases and 437 non-malformed controls from a California population-based case-control study (1987-1988 birth cohort). Increased risk of limb anomaly was observed for three SNPs: heterozygosity for F5 Arg506Gln, with an odds ratio (OR) of 2.5 (95% confidence interval (CI), 1.0, 6.5); heterozygosity for TNF (-376)G > A, OR 2.1 (0.7, 6.2); and homozygosity for NPPA 2238T > C, OR 4.0 (1.1, 15.4). We hypothesized that effects of variant genotypes in the presence of maternal smoking, and/or in the absence of supplement intake, may exceed effects of any of these factors alone. In particular, findings for polymorphisms in SERPINE1, ITGA2, SELE, TNF, LTA, NPPA, GNB3, and ADRB2 supported the hypotheses, both for smoking and for supplement intake. These results suggest involvement of genetic variation of biologically relevant candidate genes, and gene-environment interaction, for some limb anomalies whose pathogenesis may be related to altered vascular tone or integrity.",
        "keywords": [
            "blood pressure",
            "genes",
            "epidemiology",
            "cell cell interaction"
        ],
        "authors": [
            {
                "name": "Suzan L. Carmichael",
                "org": "California Birth Defects Monitoring Program, March of Dimes Birth Defects Foundation, Berkeley, California 94710, USA. sca@cbdmp.org"
            },
            {
                "name": "Gary M. Shaw",
                "org": ""
            },
            {
                "name": "David M. Iovannisci",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Richard H. Finnell",
                "org": ""
            },
            {
                "name": "Suzanne Cheng",
                "org": ""
            },
            {
                "name": "Edward J. Lammer",
                "org": ""
            }
        ],
        "venue": "American journal of medical genetics. Part A",
        "year": 2006
    },
    "q1fvmBby": {
        "id": "q1fvmBby",
        "title": "CHKA and PCYT1A gene polymorphisms, choline intake and spina bifida risk in a California population",
        "abstract": "BACKGROUND: Neural tube defects (NTDs) are among the most common of all human congenital defects. Over the last two decades, accumulating evidence has made it clear that periconceptional intake of folic acid can significantly reduce the risk of NTD affected pregnancies. This beneficial effect may be related to the ability of folates to donate methyl groups for critical physiological reactions. Choline is an essential nutrient and it is also a methyl donor critical for the maintenance of cell membrane integrity and methyl metabolism. Perturbations in choline metabolism in vitro have been shown to induce NTDs in mouse embryos. METHODS: This study investigated whether single nucleotide polymorphisms (SNPs) in human choline kinase A (CHKA) gene and CTP:phosphocholine cytidylytransferase (PCYT1A) gene were risk factors for spina bifida. Fluorescence-based allelic discrimination analysis was performed for the two CHKA intronic SNPs hCV1562388 (rs7928739) and hCV1562393, and PCYT1A SNP rs939883 and rs3772109. The study population consisted of 103 infants with spina bifida and 338 non-malformed control infants who were born in selected California counties in the period 1989–1991. RESULTS: The CHKA SNP hCV1562388 genotypes with at least one C allele were associated with a reduced risk of spina bifida (odds ratio = 0.60, 95%CI = 0.38–0.94). The PCYT1A SNP rs939883 genotype AA was associated with a twofold increased risk of spina bifida (odds ratio = 1.89, 95% CI = 0.97–3.67). These gene-only effects were not substantially modified by analytic consideration to maternal periconceptional choline intake. CONCLUSION: Our analyses showed genotype effects of CHKA and PCYT1A genes on spina bifida risk, but did not show evidence of gene-nutrient interactions. The underlying mechanisms are yet to be resolved.",
        "keywords": [
            "gene polymorphism",
            "odd ratio",
            "risk factors",
            "single nucleotide polymorphism",
            "discriminant analysis"
        ],
        "authors": [
            {
                "name": "James O Ebot Enaw",
                "org": "Center for Environmental and Genetic Medicine, Institute of Biosciences and Technology, Texas A&M University System Health Science Center, Houston, Texas 77030, USA"
            },
            {
                "name": "Huiping Zhu",
                "org": "Center for Environmental and Genetic Medicine, Institute of Biosciences and Technology, Texas A&M University System Health Science Center, Houston, Texas 77030, USA"
            },
            {
                "name": "Wei Yang",
                "org": "California Birth Defects Monitoring Program, Berkeley, CA, USA"
            },
            {
                "name": "Wei Lu",
                "org": "Center for Environmental and Genetic Medicine, Institute of Biosciences and Technology, Texas A&M University System Health Science Center, Houston, Texas 77030, USA"
            },
            {
                "name": "Gary M Shaw",
                "org": "California Birth Defects Monitoring Program, Berkeley, CA, USA"
            },
            {
                "name": "Edward J Lammer",
                "org": "Children's Hospital Oakland Research Institute, Oakland, CA, USA"
            },
            {
                "name": "Richard H Finnell",
                "org": "Center for Environmental and Genetic Medicine, Institute of Biosciences and Technology, Texas A&M University System Health Science Center, Houston, Texas 77030, USA|Center for Environmental and Rural Health, Texas A&M University, College Station, Texas 77843, USA"
            }
        ],
        "venue": "BMC Medicine",
        "year": 2006
    },
    "9HIUQbqG": {
        "id": "9HIUQbqG",
        "title": "Epidemiologic characteristics of congenital diaphragmatic hernia among 2.5 million California births, 1989-1997.",
        "abstract": "Congenital diaphragmatic hernia (CDH) is a severe birth defect of unknown etiology. The aims of the current report were to extend the literature on the descriptive epidemiology of CDH and to determine whether its mortality rate decreased in California during the study period.Using data from a large population-based registry, we ascertained 631 CDH cases from 1989 to 1997. We also classified cases as isolated or nonisolated based on the presence and type of major accompanying malformations. Approximately 2.5 million live and stillbirths occurred during the ascertainment period. Multivariate Poisson regression analysis was applied to examine the time trend and risk factors.The overall prevalence of CDH was 2.49 per 10,000 live and stillbirths and did not vary over the study period. Isolated cases, which accounted for 58% of cases, revealed a prevalence of 1.45 per 10,000. Heart malformations were the most frequent major anomalies accompanying CDH. We observed a lower risk of isolated CDH among blacks. Advanced maternal age groups had a higher risk for nonisolated CDH. Multiparous women tended to have a lower risk for nonisolated CDH. Male infants and multiple births had an increased risk for isolated and nonisolated CDH. Infant mortality was slightly decreased over the study period. CDH cases with additional anomalies had higher mortality rates than isolated cases.Our observations add to the relatively few population-based descriptive epidemiologic studies of the prevalence and mortality, and maternal and infant characteristics of CDH.",
        "keywords": [
            "epidemiology",
            "prevalence"
        ],
        "authors": [
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Suzan L Carmichael",
                "org": ""
            },
            {
                "name": "John A Harris",
                "org": ""
            },
            {
                "name": "Gary M Shaw",
                "org": ""
            }
        ],
        "venue": "Birth defects research. Part A, Clinical and molecular teratology",
        "year": 2006
    },
    "sbW4vA5I": {
        "id": "sbW4vA5I",
        "title": "PhosphatidylethanolamineN-methyltransferase (PEMT) gene polymorphisms and risk of spina bifida",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Jing Zhang",
                "org": ""
            },
            {
                "name": "Huiping Zhu",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Gary M. Shaw",
                "org": ""
            },
            {
                "name": "Edward J. Lammer",
                "org": ""
            },
            {
                "name": "Richard H. Finnell",
                "org": ""
            }
        ],
        "venue": "American Journal of Medical Genetics Part A",
        "year": 2006
    },
    "tVdZwK9j": {
        "id": "tVdZwK9j",
        "title": "Risk of limb deficiency defects associated withNAT1,NAT2,GSTT1,GSTM1, andNOS3 genetic variants, maternal smoking, and vitamin supplement intake",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Suzan L. Carmichael",
                "org": ""
            },
            {
                "name": "Gary M. Shaw",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "David M. Iovannisci",
                "org": ""
            },
            {
                "name": "Edward Lammer",
                "org": ""
            }
        ],
        "venue": "American Journal of Medical Genetics Part A",
        "year": 2006
    },
    "aCXOei19": {
        "id": "aCXOei19",
        "title": "Congenital malformations co-occurring with hypospadias in California, 1983-1997.",
        "abstract": "Investigations for co-occurring malformations can serve as a first step to discover new risk factors and provide insights into malformation etiologies. Our objective was to explore the risks of occurrence of structural congenital malformation phenotypes in 5,481 infants with hypospadias, using data from a population-based active surveillance system. Ascertainment was performed among 1,816,258 liveborn and 12,203 stillborn male offspring of women who were residents of registry counties during 1983-1997. Malformations other than hypospadias were grouped according to the 3- and 4-digit BPA malformation codes. Prevalences of each malformation grouping were calculated among all births with hypospadias and their three subgroups and all births without hypospadias but with another structural malformation. Relative risks were estimated based on the ratio of two prevalences, and the corresponding 95% confidence intervals were computed using Poisson regression models. Observed relative risks indicated that all malformation groupings were less likely to co-occur with hypospadias and their three subgroups than with other types of malformations, with relative risks ranging from 0.04 to 0.93. For most malformations, risks were relatively similar among all births with hypospadias and the three subgroups of hypospadias. The observed relative risks were not substantially changed in analyses that adjusted for maternal age, race/ethnicity, and parity. Computations were extended to 4-digit level BPA codes. Almost all observed relative risks for malformations co-occurring with hypospadias overall and three subgroups were less than 1.",
        "keywords": [
            "epidemiology",
            "birth",
            "co occurrence"
        ],
        "authors": [
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Suzan L Carmichael",
                "org": ""
            },
            {
                "name": "Gary M Shaw",
                "org": ""
            }
        ],
        "venue": "American journal of medical genetics. Part A",
        "year": 2007
    },
    "UxkN1BUY": {
        "id": "UxkN1BUY",
        "title": "Congenital malformations co‐occurring with hypospadias in California, 1983–1997",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "wei yang",
                "org": ""
            },
            {
                "name": "suzan l carmichael",
                "org": ""
            },
            {
                "name": "gary m shaw",
                "org": ""
            }
        ],
        "venue": "American Journal of Medical Genetics",
        "year": 2007
    },
    "W7L974Rv": {
        "id": "W7L974Rv",
        "title": "Maternal stressful life events and risks of birth defects.",
        "abstract": "Several previous studies suggest that maternal stress may be associated with increased risk of certain birth defects. This study examined the association of maternal stressful life events with risks of several birth defects.The data are from a recent, population-based case-control study. Telephone interviews were conducted with 1355 eligible case mothers and 700 control mothers. Maternal stress was measured by responses to 18 yes/no questions about life events that occurred from 2 months before through 2 months after conception.An increase in the stressful life events index (ie, number of \"yes\" responses to the 18 life-events questions) was associated with increased risk of cleft palate, cleft lip with or without cleft palate, d-transposition of the great arteries, and tetralogy of Fallot, after adjustment for maternal race-ethnicity, education, obesity, age, smoking, drinking, intake of folic acid-containing supplements, neighborhood crime, and food insecurity. For example, the odds ratio for a 3-unit change in the stress index was 1.45 (95% confidence interval = 1.03-2.06) for cleft palate. Increased stress was associated with an increased risk of spina bifida and anencephaly particularly among women who did not take folic acid supplements. A 3-unit change in stress was associated with a 2.35-fold increased risk of anencephaly among women who did not take supplements (CI =1.47-3.77) and a 1.42-fold increased risk among women who did (CI = 0.89-2.25).The adverse health effects of stress may include increased risks of certain birth defects.",
        "keywords": [
            "public health",
            "questionnaire",
            "risk factor",
            "risk",
            "risk assessment",
            "epidemiology"
        ],
        "authors": [
            {
                "name": "Suzan L. Carmichael",
                "org": "March of Dimes Birth Defect Foundation, California Department of Health Services, California Birth Defects Monitoring Program, Berkeley, CA, USA. sca@cbdmp.org"
            },
            {
                "name": "Gary M. Shaw",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Barbara Abrams",
                "org": ""
            },
            {
                "name": "Edward J. Lammer",
                "org": ""
            }
        ],
        "venue": "Epidemiology (Cambridge, Mass.)",
        "year": 2007
    },
    "GNM2fdeS": {
        "id": "GNM2fdeS",
        "title": "Autoantibodies to folate receptor during pregnancy and neural tube defect risk",
        "abstract": "Periconceptional folic acid can reduce the occurrence of neural tube defects (NTDs) by up to 70%, and autoantibodies for folate receptors (FRs) have been observed in serum from women with a pregnancy complicated by an NTD. This population-based cohort study has examined serum from pregnant mothers for autoantibodies to FRs, antibodies to bovine folate binding protein (FBP), and inhibition of folic acid binding to FR and FBP in association with NTD risk. The mid-gestational maternal serum specimens used for this study were collected during the 15–18th week of pregnancy. Samples were obtained from the California Birth Defects Monitoring Program; 29 mothers had a pregnancy complicated by spina bifida and 76 mothers had unaffected children. The presence of IgG and IgM antibodies to human FR, bovine FBP, and inhibition of folic acid binding to FR and FBP was determined. Higher activity of IgM to FBP in cases verses controls was observed ( P = 0.04). Higher activity of IgM and IgG autoantibodies to FR was observed ( P < 0.001 and P = 0.04, respectively). Risk estimates at two standard deviations above average control antibody concentrations were OR = 2.07 (CI = 1.02, 4.06) for anti-FBP IgM, OR = 2.15 (CI = 1.02, 4.69) for anti-FR IgG and OR = 3.19 (CI = 1.47, 6.92) for anti-FR IgM. These data support the hypothesis that high titers of antibodies and blocking of folic acid binding to FRs by maternal serum should be regarded as risk factors for NTDs. Keywords Folate receptor Autoantibodies Pregnancy Neural tube defects 1 Introduction Over the last two decades, periconceptional folic acid supplementation has been shown to significantly reduce the risk of neural tube defects (NTDs) by as much as 70% ( Berry et al., 1999; Czeizel and Dudas, 1992; Milunsky et al., 1989; MRC, 1991; Steegers-Theunissen et al., 1994; Werler et al., 1993 ). However, most pregnant women carrying an NTD-affected fetus do not have serum folate deficiency ( Kirke et al., 1993; Yates et al., 1987 ). No polymorphisms have been observed in folate receptor-α to account for effect of folic acid on NTD risk ( Barber et al., 1998 ). However, multiple polymorphisms for a variety of folate pathway enzymes have been identified, some of which have been proposed as risk factors for NTDs ( Botto and Yang, 2000; Shaw et al., 1998; van der Put et al., 1995; Zhu et al., 2003 ), but they account for only a fraction of the reduction in NTD risk following folate supplementation. The other underlying mechanisms by which folic acid supplementation decreases NTD risk are poorly understood ( Cabrera et al., 2004 ). However, evidence has emerged that maternal immunological responses can have a substantive impact on embryonic development. When antibodies to rat placenta, kidney, heart and other tissues are generated and administered to pregnant rats, they bind to the yolk sac and contribute to congenital abnormalities and embryonic death ( da Costa and Rothenberg, 1996; da Costa et al., 2003 ). It was hypothesized that the presence of antibodies binding to the yolk sac impaired the delivery of critical nutrients to the embryo ( da Costa et al., 2003; Rothenberg et al., 2004 ). Similarly, studies have also indicated that competitive inhibition of proteins such as the FR can result in cellular growth inhibition by blocking the uptake of folate ( Ebel et al., 2007; Henderson and Strauss, 1990 ). Rothenberg et al. (2004) reported autoantibodies to the FR in 75% of 12 mothers who had given birth to NTD-affected infants, but in only 8.3% of mothers of 24 non-malformed infants. Unfortunately, this provocative but small study examined only three women during pregnancy, all of whom had a pregnancy complicated by an NTD. Maternal autoantibodies to FR that produce immune responses against, or inhibit folate uptake by, the developing embryo may explain the beneficial effect of periconceptional folic acid supplementation on NTD risk. That is, supplemental folic acid may reduce the level of serum autoantibodies or compensate for blocking of the receptors caused by FR autoantibodies. Consequently nullizygous mutations for, or immunologically targeting of, folate binding protein has been demonstrated to increase risk for folate-responsive congenital anomalies in mouse and rat models ( da Costa et al., 2003; Piedrahita et al., 1999; Tang and Finnell, 2003 ). Several etiologies have been suggested for the presence of FR autoantibodies in human serum. For example, bovine folate binding protein (bFBP) (GI: 110282963) may be antigenic, and some antibodies cross-react with the endogenous receptor (GI: 544337) due to >80% protein homology as determined by the Protein Basic Local Alignment Search Tool (blastp) ( Tatusova and Madden, 1999 ). It is possible also that degradation or cleavage of FR, or the binding of an antigenic ligand, makes the receptor antigenic. The de novo production of anti-idiotypes by the variable region of an antibody could also explain the presence of maternal autoantibodies to the FR ( Schwartz, 2005 ). We hypothesized that, during pregnancy, blocking of folic acid binding to FR and serum autoantibodies to FR are risk factors for NTDs. Here, we report the results of anti-FR antibodies and folic acid blocking in serum from expectant mothers. Specifically, two preparations of human placental FR and exogenous bovine milk FBP proteins were assessed for interactions with folic acid and antibodies in maternal serum, and their measure of NTD risk was determined. 2 Materials and methods 2.1 Study design Between January 2003 and December 2004, more than 140,000 serum specimens were collected and banked from women during the 15–18th week of pregnancy. These sera were collected from women who live in selected regions in California (Orange and San Diego counties, and Central Valley counties). The specimens were collected from women as part of the Expanded Alpha-Fetoprotein (XAFP) Screening Program. Once diagnostic screening was complete, a proportion of the residual serum sample was stored frozen at −80 °C in the specimen bank. Each woman's serum specimen was record-linked with delivery outcome information to determine whether her fetus had an NTD, any other structural malformation ascertained by the California Birth Defects Monitoring Program ( Croen et al., 1991 ), or was born non-malformed. The study included deliveries that were liveborn, stillborn (fetal deaths at greater than 20 weeks post-conception), or electively terminated based on prenatal diagnoses. We identified specimens for 29 women who had NTD-affected pregnancies. A group of non-malformed controls ( n = 76) was randomly selected from specimens associated with ‘normal’ birth outcomes. This study was approved by the Committee for the Protection of Human Subjects, California Health and Human Services Agency. 2.2 Serum assays for autoantibodies against folate receptors The assay procedure used to identify the presence, absence and relative abundance of FR autoantibodies in serum samples was a modification of a microELISA assay ( Mendoza et al. (1999) . These assays were conducted directly on glass 96-well slides (Precisions Lab Products, Middleton, WI). The slides were rinsed and modified with a fresh 1% solution of (3-glycidoxypropyl) trimethoxysilane in toluene. This method has been shown to produce monolayers of epoxysilane films ( Tsukruk et al., 1999 ). Immediately after drying, slides were utilized for coupling proteins to the surface. Bovine milk folate binding proteins (FBPs) bind folates with high affinity (1:1 molar ratio) ( Jones and Nixon, 2002 ). The FBPs used in this study were either kindly provided by Jacob Selhub (FBP), isolated using previously described procedures ( Antony et al., 1982 ), or obtained commercially (FBP.2; Sigma–Aldrich, St. Louis, MO). The FRs used in this study, kindly provided by Bart Kamen(FR) and Jacob Selhub (FR.2), were isolated from two different human placentas as previously described ( Antony et al., 1981 ). The proteins were suspended in phosphate-buffered saline (PBS, pH 7.2) with 5 mM sodium azide to produce a 1 mg/mL stock solution. For printing, this solution was diluted in 50 mM NaHCO 3 (pH 8.2) at 50 μg/mL, mixed 1:1 with Protein Print Buffer (ArrayIt, Sunnyvale, CA) and printed onto the surface in 1.0 μL volumes under ambient conditions. The slides were dried under ambient conditions. Prior to the application of the serum solution, non-bound protein was removed from the wells by two washes with 1xTNT buffer (100 mM Tris–HCl pH 7.6, 150 mM NaCl, 0.05% Tween-20). All solution volumes were 20 μL per well. The amine-reactive surface was then blocked by addition of 1xTNT–methionine (1xTNT, pH 9.0 with 15 mM methionine) buffer for 5 min. The wells were washed with 1xTNT thrice, followed by addition of the serum sample to the slide. The slides and serum solutions (1:10 dilution of serum in 1xTNT) were incubated in a polycarbonate cabinet overnight (16–18 h) under ambient conditions. After incubation, wells were washed five times with 1xTNT. A secondary conjugate labeled with alkaline phosphatase and specific for the detection of human immunoglobulin G or immunoglobulin M (IgG or IgM) was diluted in 1xTNT and then applied (20 μL per well) according to the manufacturer's ELISA recommendations (Sigma–Aldrich). The slides and secondary antibody solution were incubated for 1 h under ambient conditions. Following incubation, wells were washed seven times with 1xTNT. Negative controls were prepared from antibody-depleted sera (Sigma–Aldrich). Detection of the interaction between FR or FBP, autoantibodies and the alkaline phosphatase IgG secondary conjugate was assayed by using the ELF phosphatase substrate (Molecular Probes, Eugene, OR). Slides with applied substrate were incubated for 30 min under ambient conditions. Following this incubation, slides were rinsed once with 1xTBE (10 mM Tris–borate 1 mM EDTA) followed by a Milli-Q Ultrapure water rinse. Slides were imaged using an 8-bit UV photography workstation (Kodak, New York, NY). Fluorescent signal intensities were determined using ImageJ (NIH, Bethesda, MD) and were reported as foreground signal. Competitive inhibition of folic acid binding between the serum and the immobilized protein (FR or FBP) was detected via folic acid-labeled HRP (FA-HRP, Ortho-Clinical Diagnostics, Raritan, NJ). Folic acid was removed, as described previously ( Zettner and Duly, 1975 ), by incubation with a solution (500 mM citric acid, pH 3.0) of dextran-coated charcoal (Sigma–Aldrich) for 5 min. This solution was then passed through PVDF-filtered 0.45 μm 96-well multiscreen plates (Millipore, Billerica, MA) in order to remove the dextran-coated charcoal and endogenous folic acid. The solution was neutralized by addition of 1.2 M Tris buffer (pH 9.0) in the well. These conditions were determined to remove up to 100 ng/mL serum folic acid, which exceeded the expected normal range 2.9–18 ng/mL ( Waddell et al., 1976 ). The peroxidase substrate used for detection was SuperSignal ELISA Pico Chemiluminescent Substrate (Pierce Biotechnology, Rockford, IL). Images were collected using a 96-well microplate reader (BMG Labtechnologies, Offenburg, Germany), and intensities were determined from the 16-bit images. Unlabeled folic acid was spiked (0.01–2000 ng/mL) into stripped antibody-deplete sera to generate a regression curve. All intensities were extracted, log-transformed and fitted relative to this sigmoid regression curve. 2.3 Statistical analysis The concentrations of maternal autoantibodies to the FR were examined as risk factors for NTDs. The concentration of folic acid blocked from binding FR by maternal serum was also used to estimate risk for NTDs. These risks were estimated by odds ratios (along with 95% confidence intervals) using logistic regression models. The correlation between antibody and folic acid blocking were determined by Pearson correlation. We performed data management and statistical analyses using Microsoft Excel (Microsoft Corp., Redmond, WA), GraphPad (GraphPad Software, San Diego, CA) and SAS software (SAS Institute, Cary, NC). 3 Results 3.1 Antibodies, autoantibodies, folic acid blocking, and NTD risk Functional testing of the antibody assay and folate binding assay indicated that both are functional and detect their respective interactions ( Fig. 1 ). Data analysis indicated a low coefficient of variance (average CV < 10%) for antibody detection, and a minimum detectable fold change of two could accurately be determined for both assays ( t -test, P < 0.01). The specificity of the assay was confirmed also by using other antigens, in place of folate receptors, with high expected rates of exposure ( e.g. Candida albicans and tetanus toxoid) and with no expected exposures ( e.g. keyhole limpet hemocyanin, KLH) in this population. Folic acid binding was not detected using these antigens, no serum samples were positive for KLH antibodies, and all samples had positive responses to C. albicans or tetanus toxoid, often both (data not shown). The age and ethnic background of the 29 case and the 76 control women providing serum samples during the 15–18th week of conception are shown in Table 1 . No significant differences were observed between case and control samples. Two variables approached significance, age and ethnicity, but both reflect actual differences in the case and control populations and, in order to avoid overmatching, no corrections were taken. The immunological characterization of antibodies, folic acid blocking, and NTD risk are shown in Table 2 . It was determined by serial dilution of a positive sample that a 10-unit change in mean signal equaled a halving of the antibody concentration. Significantly higher mean concentrations of IgM antibodies against FBP ( P = 0.04), IgG ( P = 0.02) and IgM ( P < 0.001) autoantibodies to the human placental FR, and IgM autoantibodies to FR.2 ( P = 0.05) were detected in serum of case mothers. In addition to mean differences, the potential continuous effect on NTD risk of these measures was estimated. We estimated risks associated with a two standard deviation increase in antibody concentrations and observed the following: OR = 2.07 (CI = 1.02, 4.06) for anti-FBP IgM, OR = 2.15 (CI = 1.02, 4.69) for anti-FR IgG, and OR = 3.19 (CI = 1.47, 6.92) for anti-FR IgM. The mean concentration of folic acid blocked from binding to FBP in serum from case women samples (3.8 ng/mL ± 10.4) was significantly higher ( P = 0.04) than control women (1.0 ng/mL ± 3.6). The mean concentration of folic acid blocked from binding to FR (8.2 ng/mL ± 12.4) was also significantly higher ( P = 0.002) in case women than in controls (2.6 ng/mL ± 5.5) and was associated with an increase in NTD risk (OR = 1.08, CI = 1.02, 1.15). For folic acid binding, the OR is based on a 1-unit change, where the unit is ng/mL. We estimated also the risk associated with a two standard deviation decrease in folic acid binding to FR and observed an OR = 2.44 (CI = 1.25, 4.93). Higher background IgG signals were observed in the antibody detection assay using antibody-depleted serum against FR. Autoantibodies, IgG, were detected also by Western and ELISA of the FR preparation (data not shown); however, no additional placenta remained to confirm that antibodies were bound to it prior to FR purification. 3.2 Correlations The Pearson correlation coefficients among controls ( Table 3 ) indicated that 13 of the 28 correlations were not significant. The highest correlations found in controls (0.78, P < 0.0001), also found in cases (0.94, P < 0.0001), were between anti-FBP IgM and anti-FBP.2 IgM measurements. The Pearson correlation coefficients among cases indicated that 25 of 28 antibody measurements were correlated; the three exceptions were with IgG to FBP (anti-FBP IgG). Specifically, anti-FBP IgG was not significantly correlated with IgM to FR (anti-FR IgM), nor was it correlated with IgM or IgG autoantibodies against FR.2 (anti-FR.2 IgM, anti-FR.2 IgG). Other highly significant correlations in both groups included case (0.80, P < 0.001) and control (0.68, P < 0.001) anti-FBP.2 IgM and anti-FR.2 IgM, case (0.85, P < 0.001) and control (0.49, P < 0.001) anti-FBP IgM and anti-FR IgM, case (0.68, P < 0.001) and control (0.67, P < 0.001) anti-FBP IgM and anti-FR.2 IgM, and case (0.88, P < 0.001) and control (0.51, P < 0.001) anti-FBP.2 IgM and anti-FR IgM. In regard to folic acid, the only significant correlation in both cases (0.51, P = 0.006) and controls (0.27, P = 0.02) was between the blocking of folic acid from binding of FBP (FBP FA) and antibodies against FBP (anti-FBP IgM). 4 Discussion This study of mid-gestational serum samples from NTD-affected pregnancies compared to pregnancies involving non-malformed fetuses indicates that high concentrations of IgG or IgM antibodies to FRs or FBPs are risk factors for NTDs. During the fourth week of gestation, the neural tube closes and the human embryo is interstitially implanted into the uterine wall, and migration of syncitiotrophoblasts and cytotrophoblasts has formed chorionic villi that cover the entire surface of the blastocyst ( Cross et al., 1994 ). The cytotrophoblasts of these villi have been observed to function as a barrier to the transport of IgG during this stage of development ( Bright and Ockleford, 1995 ). These observations suggest that, during neural tube closure, IgM and IgG antibodies are prohibited from reaching the embryo. However, autoantibodies may indirectly influence neural tube closure and NTD risk. These indirect influences would include IgG or IgM immune responses at the maternal–embryonic trophoblast interface and inhibition of nutrient transport to the blastocyst. In support of inhibition of nutrient transport, we observed also that the serum from mothers who delivered an NTD-affected child significantly blocked higher concentrations of folic acid from binding to FBP and FR versus serum from mothers of an unaffected child. However, several samples with high titers of antibodies allowed FR and FBP still to bind folic acid. This may indicate that the antibodies can bind FR and FBP at different locations, but they must interact with specific epitopes in order to inhibit folic acid binding. In support of direct and indirect influences, binding to or blocking of folic acid to FR increased NTD risk estimates to the greatest extent. Specifically, IgM autoantibodies, folic acid blocking and IgG autoantibodies against FR had the highest estimates of NTD risk at two standard deviations ( Table 2 ). The IgM and IgG concentrations are highly correlated in all case samples and in FBP.2 in controls ( Table 3 ). This may indicate an ongoing primary immune response, which begins with IgM production and is followed by IgG ( Perelson et al., 1980 ). With regard to the positive association of antibodies for FRs and FBPs, the >80% homology between these proteins (determined by blastp ( Tatusova and Madden, 1999 ); FBP, GI: 110282963; FR, GI: 544337) may allow cross-reaction with most serum IgM and some IgG antibodies, resulting in significant correlations between the different proteins tested. However, the similarities of these proteins does not explain the difference in the number of significant correlations observed in controls ( N = 18) versus cases ( N = 32). This difference in significant correlations may be caused by a decrease in antibody specificity, more cross-reactivity or a more concerted immune response in cases relative to controls. The forbidden clone hypothesis indicates that autoimmunity is mitigated by clonal selection ( Burnet, 1972 ), but if proteins expressed by developmental tissues undergo modification during periods of inflammation or metabolic stress, an immune response may be activated against the modified forms ( McCully, 1993,1994; Undas et al., 2004 ). Folic acid supplementation has been reported to lower homocysteine, homocysteine thiolactone and autoantibodies against homocysteinylated serum proteins in a majority of patients with coronary artery disease ( Undas et al., 2006 ). Based on these observations, we suspect that the etiology of FR autoantibodies may be due in part to post-translational modification of proteins by homocysteine thiolactone in vivo and that autoantibodies produced against homocysteinylated FRs may cross-react with native FR and increase the risk for folate-responsive birth defects, such as NTDs. As proposed and observed previously, these post-translation modification may also be part of other autoimmune phenomenon ( Cabrera et al., 2004; Perla-Kajan et al., 2007 ). Specifically, the production of antigenic proteins by homocysteine thiolactone may influence the etiology of autoantibodies to synovial cells in arthritis, antiphospholipids in lupus erythematosus, thyroid stimulating hormone receptor in Grave's disease and intrinsic factor in pernicious amemia ( Lazzerini et al., 2007; McCully, 1994 ). A previous study identified an association (relative risk of 27.0) between FR autoantibodies and NTDs, with a reported frequency of 10% for the presence of autoantibodies among controls ( Rothenberg et al., 2004 ). We observed continuous distributions of antibodies amongst cases and controls, all mean antibody concentrations for cases were higher than controls, and several concentrations differed significantly ( Table 2 ). The major difference between these experiments were serum collection times ( i.e. only three mid-gestational serum samples from women with a pregnancy complicated by a neural tube defect and no mid-gestational serum controls were used in the other study). We utilized smaller testing volumes (2–10 μL), 96-well processing and enzymatic detection for the presence or absence of the autoantibodies (anti-IgG-AP or anti-IgM-AP) and folic acid (FA-HRP). Additionally, we observed that the source of the FRs or FBPs can modify the detected interactions with serum antibodies ( Tables 2 and 3 ). This study was conducted during a time period when the food supply was fortified with folic acid, so this may explain the low ∼1/4700 incidence of NTDs and also makes it unlikely that all of the observed NTDs are folate-responsive. However, if folic acid supplementation reduces the homocysteinylation of other proteins critical for embryonic development, antibodies against these proteins may also modify birth defect risk. Untangling these complex interactions and investigating methods that reduce the level of pathogenic autoantibodies will serve as the subject for future studies. Acknowledgments The authors are grateful to Drs. Jacob Selhub and Bart Kamen for providing folate receptors for these experiments. This work was partially supported by the NIH/NHLBI P30 HL66398, and by funds from the Centers of Disease Control and Prevention, Centers of Excellence Award no. U50/CCU913241. References Antony et al., 1981 A.C. Antony C. Utley K.C. Van Horne J.F. Kolhouse Isolation and characterization of a folate receptor from human placenta J. Biol. Chem. 256 1981 9684 9692 Antony et al., 1982 A.C. Antony C.S. Utley P.D. Marcell J.F. Kolhouse Isolation, characterization, and comparison of the solubilized particulate and soluble folate binding proteins from human milk J. Biol. Chem. 257 1982 10081 10089 Barber et al., 1998 R.C. Barber G.M. Shaw E.J. Lammer K.A. Greer T.A. Biela S.W. Lacey C.R. Wasserman R.H. Finnell Lack of association between mutations in the folate receptor-alpha gene and spina bifida Am. J. Med. Genet. 76 1998 310 317 Berry et al., 1999 R.J. Berry Z. Li J.D. Erickson S. Li C.A. Moore H. Wang J. Mulinare P. Zhao L.Y. Wong J. Gindler Prevention of neural-tube defects with folic acid in China. China–U.S. Collaborative Project for Neural Tube Defect Prevention [corrected; erratum to be published] N. Engl. J. Med. 341 1999 1485 1490 Botto and Yang, 2000 L.D. Botto Q. Yang 5,10-Methylenetetrahydrofolate reductase gene variants and congenital anomalies: a HuGE review Am. J. Epidemiol. 151 2000 862 877 Bright and Ockleford, 1995 N.A. Bright C.D. Ockleford Cytotrophoblast cells: a barrier to maternofetal transmission of passive immunity J. Histochem. Cytochem. 43 1995 933 944 Burnet, 1972 F.M. Burnet A reassessment of the forbidden clone hypothesis of autoimmune disease Aust. J. Exp. Biol. Med. Sci. 50 1972 1 9 Cabrera et al., 2004 R.M. Cabrera D.S. Hill A.J. Etheredge R.H. Finnell Investigations into the etiology of neural tube defects Birth Defects Res. C. Embryo Today 72 2004 330 344 Croen et al., 1991 L.A. Croen G.M. Shaw N.G. Jensvold J.A. Harris Birth defects monitoring in California: a resource for epidemiological research Paediatr. Perinat. Epidemiol. 5 1991 423 427 Cross et al., 1994 J.C. Cross Z. Werb S.J. Fisher Implantation and the placenta: key pieces of the development puzzle Science 266 1994 1508 1518 Czeizel and Dudas, 1992 A.E. Czeizel I. Dudas Prevention of the first occurrence of neural-tube defects by periconceptional vitamin supplementation N. Engl. J. 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Nixon Tetrahydrofolates are greatly stabilized by binding to bovine milk folate-binding protein J. Nutr. 132 2002 2690 2694 Kirke et al., 1993 P.N. Kirke A.M. Molloy L.E. Daly H. Burke D.G. Weir J.M. Scott Maternal plasma folate and vitamin B12 are independent risk factors for neural tube defects Q. J. Med. 86 1993 703 708 Lazzerini et al., 2007 P.E. Lazzerini P.L. Capecchi E. Selvi S. Lorenzini S. Bisogno M. Galeazzi F. Laghi Pasini Hyperhomocysteinemia, inflammation and autoimmunity Autoimmun. Rev. 6 2007 503 509 McCully, 1993 K.S. McCully Chemical pathology of homocysteine. I. Atherogenesis Ann. Clin. Lab. Sci. 23 1993 477 493 McCully, 1994 K.S. McCully Chemical pathology of homocysteine. III. Cellular function and aging Ann. Clin. Lab. Sci. 24 1994 134 152 Mendoza et al., 1999 L.G. Mendoza P. McQuary A. Mongan R. Gangadharan S. Brignac M. 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Haemost. 96 2006 342 347 van der Put et al., 1995 N.M.J. van der Put R.P.M. Steegers-Theunissen P. Frosst F.J.M. Trijbels T.K. Eskes L.P. van den Heuvel E.C.M. Mariman M. den Heyer R. Rozen H.J. Blom Mutated methylenetetrahydrofolate reductase as a risk factor for spina bifida Lancet 346 1995 1070 1071 Waddell et al., 1976 C.C. Waddell P.A. Domstad F.J. Pircher S.R. Lerner J.A. Brown B.K. Lawhorn Serum folate levels. Comparison of microbiologic assay and radioisotope kit methods Am. J. Clin. Pathol. 66 1976 746 752 Werler et al., 1993 M.M. Werler S. Shapiro A.A. Mitchell Periconceptional folic acid exposure and risk of occurrent neural tube defects JAMA 269 1993 1257 1261 Yates et al., 1987 J.R. Yates M.A. Ferguson-Smith A. Shenkin R. Guzman-Rodriguez M. White B.J. Clark Is disordered folate metabolism the basis for the genetic predisposition to neural tube defects? Clin. Genet. 31 1987 279 287 Zettner and Duly, 1975 A. Zettner P.E. Duly Relative efficacy of separation of “free” and “bound” (3′,5′-3H) pteroylglutamate by charcoal coated with various materials Clin. Chem. 21 1975 1927 1931 Zhu et al., 2003 H. Zhu N.J. Wicker G.M. Shaw E.J. Lammer K. Hendricks L. Suarez M. Canfield R.H. Finnell Homocysteine remethylation enzyme polymorphisms and increased risks for neural tube defects Mol. Genet. Metab. 78 2003 216 221",
        "keywords": [],
        "authors": [
            {
                "name": "Robert M. Cabrera",
                "org": "Texas A&M Institute for Genomic Medicine, Houston, TX, USA"
            },
            {
                "name": "Gary M. Shaw",
                "org": "March of Dimes California Research Division, Oakland, CA, USA"
            },
            {
                "name": "Johnathan L. Ballard",
                "org": "Center for Environmental and Genetic Medicine, Institute for Biosciences and Technology, Texas A&M University Health Science Center, Houston, TX, USA"
            },
            {
                "name": "Suzan L. Carmichael",
                "org": "March of Dimes California Research Division, Oakland, CA, USA"
            },
            {
                "name": "Wei Yang",
                "org": "March of Dimes California Research Division, Oakland, CA, USA"
            },
            {
                "name": "Edward J. Lammer",
                "org": "Children's Hospital Oakland Research Institute, Oakland, CA, USA"
            },
            {
                "name": "Richard H. Finnell",
                "org": ""
            }
        ],
        "venue": "Journal of Reproductive Immunology",
        "year": 2008
    },
    "43fKzSU0": {
        "id": "43fKzSU0",
        "title": "Nicotinamide<i>N</i>-methyl transferase (<i>NNMT</i>) gene polymorphisms and risk for spina bifida",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Wei Lu",
                "org": ""
            },
            {
                "name": "Huiping Zhu",
                "org": ""
            },
            {
                "name": "Shu Wen",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Gary M. Shaw",
                "org": ""
            },
            {
                "name": "Edward J. Lammer",
                "org": ""
            },
            {
                "name": "Richard H. Finnell",
                "org": ""
            }
        ],
        "venue": "Birth Defects Research Part A-clinical and Molecular Teratology",
        "year": 2008
    },
    "zze3RfB1": {
        "id": "zze3RfB1",
        "title": "Nutrient intakes in women and congenital diaphragmatic hernia in their offspring.",
        "abstract": "Congenital diaphragmatic hernia (CDH) is a severe birth defect where there is an opening in the diaphragm through which a portion of the abdominal contents protrudes into the thoracic cavity. The etiologies of CDH remain unknown, although experimental animal data suggest dietary factors might play a role. This study examined whether maternal nutrient intakes were associated with delivering infants with CDH.We analyzed infants with isolated CDH who were born from 1997 to 2003 and recruited into the National Birth Defects Prevention Study (NBDPS), a multisite, population-based case-control study. Exposure data were obtained from telephone interviews, which were completed within 24 months after delivery, and were available for 377 case mothers and 5,008 control mothers. A food frequency questionnaire was used to derive nutrient intakes during the year before pregnancy.A crude OR of 0.6 (95% CI: 0.3-1.0) was observed for higher intake of choline. Elevated ORs (1.4 to 1.7) were found for lower intakes of choline, cysteine, methionine, and protein. Among women who took vitamin supplements, higher intakes of B vitamins (i.e., folate, vitamin B1, B2, B6, and B12), minerals (i.e., calcium, iron, magnesium, and zinc), and vitamin E were inversely associated with CDH (ORs from 0.7-0.3). Moreover, among women who did not take vitamin supplements, lower intakes of calcium, retinol, selenium, vitamin B12, and vitamin E had positive associations with CDH (ORs from 1.4 to 2.1).Our observations contribute to a limited body of evidence suggesting a woman's periconceptional diet might be associated with CDH in her offspring.",
        "keywords": [
            "nutrition"
        ],
        "authors": [
            {
                "name": "Yang Wei",
                "org": "March of Dimes, California Research Division, Oakland, California 94609, USA. WYang@marchofdimes.com"
            },
            {
                "name": "Shaw Gary M",
                "org": ""
            },
            {
                "name": "Carmichael Suzan L",
                "org": ""
            },
            {
                "name": "Rasmussen Sonja A",
                "org": ""
            },
            {
                "name": "Waller D Kim",
                "org": ""
            },
            {
                "name": "Pober Barbara R",
                "org": ""
            },
            {
                "name": "Anderka Marlene",
                "org": ""
            },
            {
                "name": "null null",
                "org": ""
            }
        ],
        "venue": "Birth defects research. Part A, Clinical and molecular teratology",
        "year": 2008
    },
    "86RHd9X6": {
        "id": "86RHd9X6",
        "title": "Hypospadias and Intake of Nutrients Related to One-Carbon Metabolism. Commentary",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Suzan L. Carmichael",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Adolfo Correa",
                "org": ""
            },
            {
                "name": "Richard S. Olney",
                "org": ""
            },
            {
                "name": "Gary M. Shaw",
                "org": ""
            },
            {
                "name": "Jean G. Hollowell",
                "org": ""
            },
            {
                "name": "Caleb P. Nelson",
                "org": ""
            }
        ],
        "venue": "The Journal of Urology",
        "year": 2009
    },
    "KWbNBxdZ": {
        "id": "KWbNBxdZ",
        "title": "Orofacial clefts in the National Birth Defects Prevention Study, 1997-2004",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Alicia E. Genisca",
                "org": ""
            },
            {
                "name": "Jaime L. Frías",
                "org": ""
            },
            {
                "name": "Cheryl S. Broussard",
                "org": ""
            },
            {
                "name": "Margaret A. Honein",
                "org": ""
            },
            {
                "name": "Edward J. Lammer",
                "org": ""
            },
            {
                "name": "Cynthia A. Moore",
                "org": ""
            },
            {
                "name": "Gary M. Shaw",
                "org": ""
            },
            {
                "name": "Jeffrey C. Murray",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Sonja A. Rasmussen",
                "org": ""
            }
        ],
        "venue": "American Journal of Medical Genetics Part A",
        "year": 2009
    },
    "dUBW5paQ": {
        "id": "dUBW5paQ",
        "title": "118 SNPs of folate-related genes and risks of spina bifida and conotruncal heart defects",
        "abstract": "BACKGROUND: Folic acid taken in early pregnancy reduces risks for delivering offspring with several congenital anomalies. The mechanism by which folic acid reduces risk is unknown. Investigations into genetic variation that influences transport and metabolism of folate will help fill this data gap. We focused on 118 SNPs involved in folate transport and metabolism. METHODS: Using data from a California population-based registry, we investigated whether risks of spina bifida or conotruncal heart defects were influenced by 118 single nucleotide polymorphisms (SNPs) associated with the complex folate pathway. This case-control study included 259 infants with spina bifida and a random sample of 359 nonmalformed control infants born during 1983–86 or 1994–95. It also included 214 infants with conotruncal heart defects born during 1983–86. Infant genotyping was performed blinded to case or control status using a designed SNPlex assay. We examined single SNP effects for each of the 118 SNPs, as well as haplotypes, for each of the two outcomes. RESULTS: Few odds ratios (ORs) revealed sizable departures from 1.0. With respect to spina bifida, we observed ORs with 95% confidence intervals that did not include 1.0 for the following SNPs (heterozygous or homozygous) relative to the reference genotype: BHMT (rs3733890) OR = 1.8 (1.1–3.1), CBS (rs2851391) OR = 2.0 (1.2–3.1); CBS (rs234713) OR = 2.9 (1.3–6.7); MTHFD1 (rs2236224) OR = 1.7 (1.1–2.7); MTHFD1 (hcv11462908) OR = 0.2 (0–0.9); MTHFD2 (rs702465) OR = 0.6 (0.4–0.9); MTHFD2 (rs7571842) OR = 0.6 (0.4–0.9); MTHFR (rs1801133) OR = 2.0 (1.2–3.1); MTRR (rs162036) OR = 3.0 (1.5–5.9); MTRR (rs10380) OR = 3.4 (1.6–7.1); MTRR (rs1801394) OR = 0.7 (0.5–0.9); MTRR (rs9332) OR = 2.7 (1.3–5.3); TYMS (rs2847149) OR = 2.2 (1.4–3.5); TYMS (rs1001761) OR = 2.4 (1.5–3.8); and TYMS (rs502396) OR = 2.1 (1.3–3.3). However, multiple SNPs observed for a given gene showed evidence of linkage disequilibrium indicating that the observed SNPs were not individually contributing to risk. We did not observe any ORs with confidence intervals that did not include 1.0 for any of the studied SNPs with conotruncal heart defects. Haplotype reconstruction showed statistical evidence of nonrandom associations with TYMS, MTHFR, BHMT and MTR for spina bifida. CONCLUSION: Our observations do not implicate a particular folate transport or metabolism gene to be strongly associated with risks for spina bifida or conotruncal defects.",
        "keywords": [
            "risk factors",
            "odds ratio",
            "single nucleotide polymorphism",
            "human genetics",
            "confidence interval",
            "odd ratio",
            "linkage disequilibrium",
            "case control studies",
            "genetic variation",
            "case control study",
            "genotype",
            "random sampling",
            "haplotypes"
        ],
        "authors": [
            {
                "name": "Gary M Shaw",
                "org": "Department of Pediatrics, Division of Neonatal & Developmental Medicine, Stanford University School of Medicine, Stanford, CA, USA|School of Public Health, University of California, Berkeley, School of Public Health, Berkeley, CA, USA|Children's Hospital Oakland Research Institute, Oakland, CA, USA"
            },
            {
                "name": "Wei Lu",
                "org": "Institute of Biosciences and Technology, Texas A&M Health Science Center, Houston, TX, USA"
            },
            {
                "name": "Huiping Zhu",
                "org": "Institute of Biosciences and Technology, Texas A&M Health Science Center, Houston, TX, USA"
            },
            {
                "name": "Wei Yang",
                "org": "California Research Division, March of Dimes, California Research Division, Oakland, CA, USA"
            },
            {
                "name": "Farren BS Briggs",
                "org": "School of Public Health, University of California, Berkeley, School of Public Health, Berkeley, CA, USA"
            },
            {
                "name": "Suzan L Carmichael",
                "org": "California Research Division, March of Dimes, California Research Division, Oakland, CA, USA|Children's Hospital Oakland Research Institute, Oakland, CA, USA"
            },
            {
                "name": "Lisa F Barcellos",
                "org": "School of Public Health, University of California, Berkeley, School of Public Health, Berkeley, CA, USA"
            },
            {
                "name": "Edward J Lammer",
                "org": "Children's Hospital Oakland Research Institute, Oakland, CA, USA"
            },
            {
                "name": "Richard H Finnell",
                "org": "Institute of Biosciences and Technology, Texas A&M Health Science Center, Houston, TX, USA"
            }
        ],
        "venue": "BMC Medical Genetics",
        "year": 2009
    },
    "AqAjjDxI": {
        "id": "AqAjjDxI",
        "title": "Hypospadias and Intake of Nutrients Related to One-Carbon Metabolism",
        "abstract": "Conclusions This study suggests an association of hypospadias with intake of certain nutrients related to one-carbon metabolism.",
        "keywords": [
            "folic acid",
            "expected due date",
            "maternal nutrition physiology",
            "USDA",
            "EDD",
            "hypospadias",
            "United States Department of Agriculture"
        ],
        "authors": [
            {
                "name": "Suzan L. Carmichael",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": "California Research Division, March of Dimes Foundation, Oakland, California"
            },
            {
                "name": "Adolfo Correa",
                "org": "National Center on Birth Defects and Developmental Disabilities, CDC, Atlanta, Georgia"
            },
            {
                "name": "Richard S. Olney",
                "org": "National Center on Birth Defects and Developmental Disabilities, CDC, Atlanta, Georgia"
            },
            {
                "name": "Gary M. Shaw",
                "org": "California Research Division, March of Dimes Foundation, Oakland, California"
            }
        ],
        "venue": "The Journal of Urology",
        "year": 2009
    },
    "s4uUtRv8": {
        "id": "s4uUtRv8",
        "title": "Chromosomal abnormalities among children born with conotruncal cardiac defects",
        "abstract": "",
        "keywords": [
            "karyotyping",
            "case control studies",
            "sex chromosomes"
        ],
        "authors": [
            {
                "name": "Edward J. Lammer",
                "org": ""
            },
            {
                "name": "Jacqueline S. Chak",
                "org": ""
            },
            {
                "name": "David M. Iovannisci",
                "org": ""
            },
            {
                "name": "Kathleen Schultz",
                "org": ""
            },
            {
                "name": "Kazutoyo Osoegawa",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Suzan L. Carmichael",
                "org": ""
            },
            {
                "name": "Gary M. Shaw",
                "org": ""
            }
        ],
        "venue": "Birth Defects Research Part A-clinical and Molecular Teratology",
        "year": 2009
    },
    "U1wUBwR1": {
        "id": "U1wUBwR1",
        "title": "Genetic polymorphisms in the thioredoxin 2 (TXN2) gene and risk for spina bifida.",
        "abstract": "TXN2 encodes human thioredoxin 2, a small redox protein important in cellular antioxidant defenses, as well as in the regulation of apoptosis. Txn2 knockout mice fail to complete neural tube closure by E10.5 and die in utero. We hypothesized that genetic variation in human TXN2 gene may alter the function of the encoded protein in a manner associated with an increased risk for neural tube defects (NTDs). A DNA re-sequencing effort of the human TXN2 gene was taken. After a variation in the promoter was identified, the transcriptional activity of different alleles was investigated. The possible association between these variations and the risk of spina bifida was further evaluated in a subset of samples obtained from a large population-based case-control study in California in two different ethnicity groups, non-Hispanic white and Hispanic white. We identified a novel promoter insertion polymorphism located 9 base pairs upstream of the transcription start site of exon 1(-9 insertion). The GA, G and GGGA insertions were associated with a marked decrease of transcriptional activity when overexpressed in both U2-OS (an osteosarcoma cell line) and 293 cells (derived from human embryonic kidney). Further analysis revealed that the GA insertion was associated with increased spina bifida risk for Hispanic whites. Our study revealed a novel Ins/Del polymorphism in the human TXN2 gene proximal promoter region that altered the transcriptional activity and is associated with spina bifida risk. This polymorphism may be a genetic modifier of spina bifida risk in this California population.",
        "keywords": [
            "thioredoxin"
        ],
        "authors": [
            {
                "name": "Shu Wen",
                "org": "Center for Environmental and Genetic Medicine, Institute of Biosciences and Technology, Texas A&amp;M Health Science Center, Houston, TX 77030, USA."
            },
            {
                "name": "Wei Lu",
                "org": ""
            },
            {
                "name": "Huiping Zhu",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Gary M. Shaw",
                "org": ""
            },
            {
                "name": "Edward J. Lammer",
                "org": ""
            },
            {
                "name": "Ana Islam",
                "org": ""
            },
            {
                "name": "Richard H. Finnell",
                "org": ""
            }
        ],
        "venue": "American journal of medical genetics. Part A",
        "year": 2009
    },
    "WrsGRI71": {
        "id": "WrsGRI71",
        "title": "Periconceptional nutrient intakes and risks of neural tube defects in California.",
        "abstract": "This study investigated the association of neural tube defects (NTDs) with maternal periconceptional intake of folic acid-containing supplements and dietary nutrients, including folate, among deliveries that occurred after folic acid fortification in selected California counties.The population-based case-control study included fetuses and live born infants with spina bifida (189) or anencephaly (141) and 625 nonmalformed, live born controls delivered from 1999 to 2003. Mothers reported supplement use during telephone interviews, which included a 107-item food frequency questionnaire. For dietary nutrients, intakes <25th, 25th to <75th (reference), and > or =75th percentile were compared, based on control distributions.After adjustment for potential confounders, any versus no supplement intake resulted in ORs of 0.8 (95% CI, 0.5-1.3) for anencephaly and 0.8 (95% CI, 0.6-1.2) for spina bifida. After stratification by maternal intake of vitamin supplements, most factors in the glycemic pathway were not associated with either NTD, with the exception of low levels of fructose and glucose that were significantly associated with anencephaly. Some nutrients that contribute to one-carbon metabolism showed lowered risks (folate, riboflavin, vitamins B(6) and B(12)); others did not (choline, methionine, zinc). Antioxidant nutrients tended to be associated with lowered risks (vitamins C, E, A, beta-carotene, lutein).Mothers' intake of vitamin supplements was modestly if at all associated with a lowered risk of NTDs. Dietary intake of several nutrients contributing to one-carbon metabolism and oxidative stress were associated with reduced NTD risk.",
        "keywords": [
            "nutrition"
        ],
        "authors": [
            {
                "name": "Suzan L. Carmichael",
                "org": "California Research Division, March of Dimes Foundation, Oakland, California 94609-1673, USA. SCarmichael@marchofdimes.com"
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Gary M. Shaw",
                "org": ""
            }
        ],
        "venue": "Birth defects research. Part A, Clinical and molecular teratology",
        "year": 2010
    },
    "RZaQB06d": {
        "id": "RZaQB06d",
        "title": "Genes encoding critical transcriptional activators for murine neural tube development and human spina bifida: a case-control study.",
        "abstract": "Spina bifida is a malformation of the neural tube and is the most common of neural tube defects (NTDs). The etiology of spina bifida is largely unknown, although it is thought to be multi-factorial, involving multiple interacting genes and environmental factors. Mutations in transcriptional co-activator genes-Cited2, p300, Cbp, Tfap2α, Carm1 and Cart1 result in NTDs in murine models, thus prompt us to investigate whether homologues of these genes are associated with NTDs in humans.Data and biological samples from 297 spina bifida cases and 300 controls were derived from a population-based case-control study conducted in California. 37 SNPs within CITED2, EP300, CREBBP, TFAP2A, CARM1 and ALX1 were genotyped using an ABI SNPlex assay. Odds ratios and 95% confidence intervals were calculated for alleles, genotypes and haplotypes to evaluate the risk for spina bifida.Several SNPs showed increased or decreased risk, including CITED2 rs1131431 (OR = 5.32, 1.04~27.30), EP300 rs4820428 (OR = 1.30, 1.01~1.67), EP300 rs4820429 (OR = 0.50, 0.26~0.50, in whites, OR = 0.7, 0.49~0.99 in all subjects), EP300 rs17002284 (OR = 0.43, 0.22~0.84), TFAP2A rs3798691 (OR = 1.78, 1.13~2.87 in Hispanics), CREBBP rs129986 (OR = 0.27, 0.11~0.69), CARM1 rs17616105 (OR = 0.41, 0.22~0.72 in whites). In addition, one haplotype block in EP300 and one in TFAP2A appeared to be associated with increased risk.Modest associations were observed in CITED2, EP300, CREBBP, TFAP2A and CARM1 but not ALX1. However, these modest associations were not statistically significant after correction for multiple comparisons. Searching for potential functional variants and rare causal mutations is warranted in these genes.",
        "keywords": [
            "multiple comparisons",
            "case control studies",
            "confidence interval",
            "haplotypes",
            "genotype",
            "odd ratio",
            "risk factors",
            "odds ratio",
            "repressor proteins",
            "case control study",
            "statistical significance",
            "human genetics"
        ],
        "authors": [
            {
                "name": "Wei Lu",
                "org": "Institute of Biosciences and Technology, Texas A&M University System Health Science Center, Houston, TX, USA"
            },
            {
                "name": "Adrian R Guzman",
                "org": "Institute of Biosciences and Technology, Texas A&M University System Health Science Center, Houston, TX, USA"
            },
            {
                "name": "Wei Yang",
                "org": "Stanford University, Stanford, CA, USA"
            },
            {
                "name": "Claudia J Chapa",
                "org": "Dell Pediatric Research Institute, UT Austin, Austin, TX, USA"
            },
            {
                "name": "Gary M Shaw",
                "org": "Stanford University, Stanford, CA, USA"
            },
            {
                "name": "Robert M Greene",
                "org": "University of Louisville Birth Defects Center, Louisville, KY, USA"
            },
            {
                "name": "M Michele Pisano",
                "org": "University of Louisville Birth Defects Center, Louisville, KY, USA"
            },
            {
                "name": "Edward J Lammer",
                "org": "Children's Hospital Oakland Research Institute, Oakland, CA, USA"
            },
            {
                "name": "Richard H Finnell",
                "org": "Dell Pediatric Research Institute, UT Austin, Austin, TX, USA"
            },
            {
                "name": "Huiping Zhu",
                "org": "Dell Pediatric Research Institute, UT Austin, Austin, TX, USA"
            }
        ],
        "venue": "BMC medical genetics",
        "year": 2010
    },
    "7Rs0faJr": {
        "id": "7Rs0faJr",
        "title": "Periconceptional nutrient intakes and risks of conotruncal heart defects.",
        "abstract": "Few inquiries into periconceptional nutrition, other than folate, and risk of heart defects exist. We investigated the observed association between conotruncal heart defects and periconceptional vitamin use, as well as potential associations with other dietary nutrients.Data derived from a population-based, case-control study of fetuses and liveborn infants among California births between July 1999 and June 2004; 76% of eligible case mothers and 77% of eligible control mothers were interviewed. Cases included 140 with d-transposition of great arteries (dTGA), and 163 with tetralogy of Fallot (TOF). Total number of controls was 698. Use of vitamins was elicited by questionnaire for the periconceptional period. Dietary nutrient intake was elicited by a well-known food frequency questionnaire.The odds ratio for dTGA associated with supplemental vitamin use was 1.0 (95% confidence interval [CI], 0.7-1.5) and for TOF was 0.9 (95% CI, 0.6-1.3). We observed increased risks associated with lower dietary intakes of linoleic acid, total carbohydrate, and fructose for dTGA, whereas decreased risks were observed for lower intakes of total protein and methionine for TOF. Lower dietary intake of several micronutrients-namely folate, niacin, riboflavin, and vitamins B(12), A, and E, even after simultaneous adjustment for other studied nutrients-was associated with increased risk of dTGA but not TOF. These associations were observed among women who did not use vitamin supplements periconceptionally. Analytic consideration of several potential confounders did not reveal alternative interpretations of the results.Evidence continues to accumulate to show that nutrients, particularly folate, influence risks of structural birth defects. Our results extend observations that other nutrients may also be important in heart development.",
        "keywords": [
            "case control",
            "case control studies",
            "young adult",
            "nutrition",
            "odds ratio"
        ],
        "authors": [
            {
                "name": "Gary M. Shaw",
                "org": "Stanford University School of Medicine, Stanford, California 94305, USA. gmshaw@stanford.edu"
            },
            {
                "name": "Suzan L. Carmichael",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Edward J. Lammer",
                "org": ""
            }
        ],
        "venue": "Birth defects research. Part A, Clinical and molecular teratology",
        "year": 2010
    },
    "YnT9cgLM": {
        "id": "YnT9cgLM",
        "title": "Paternal age and congenital malformations in offspring in California, 1989-2002.",
        "abstract": "This study examined the association between paternal age and a wide range of structural birth defects. Data were drawn from The California Birth Defects Monitoring Program, a population-based active surveillance system for collecting information on infants and fetuses with defects born between 1989 and 2002. The analysis included 46,114 cases with defects, plus a random sample of 36,838 non-malformed births. After adjustment for maternal age, risks of anomalies of the nervous system for 38 and 42 year-old fathers, as compared to 29 year-old fathers, were 1.05-fold [1.00, 1.11] and 1.10-fold [1.02, 1.18] higher, respectively. Similar results were observed for anomalies of the limbs, where 38 and 42 year-old fathers had a 1.06-fold [1.02, 1.11] and 1.11-fold [1.05, 1.18] higher risk, respectively. Risks of anomalies of the integument were 1.05-fold [1.00, 1.09] and 1.10-fold [1.03, 1.16] higher for 38 and 42 year olds, respectively. Young paternal age, i.e., less than 29 years, was associated with an increased risk of amniotic bands (OR: 0.87 [0.78, 0.97]), pyloric stenosis (OR: 0.93 [0.90, 0.96]) and anomalies of the great veins (OR: 0.93 [0.87, 1.00]). In sum, both advanced and young paternal age was associated with select birth defects in California between 1989 and 2002.",
        "keywords": [
            "congenital malformations paternal age birth defects"
        ],
        "authors": [
            {
                "name": "Jagteshwar Grewal",
                "org": "Division of Epidemiology, Statistics and Prevention Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD USA"
            },
            {
                "name": "Suzan L Carmichael",
                "org": "Stanford University, Palo Alto, CA USA"
            },
            {
                "name": "Wei Yang",
                "org": "Stanford University, Palo Alto, CA USA"
            },
            {
                "name": "Gary M Shaw",
                "org": "Stanford University, Palo Alto, CA USA"
            }
        ],
        "venue": "Maternal and child health journal",
        "year": 2012
    },
    "PCrd1n22": {
        "id": "PCrd1n22",
        "title": "Reduced Risks of Neural Tube Defects and Orofacial Clefts With Higher Diet Quality",
        "abstract": "",
        "keywords": [
            "obesity",
            "case control studies"
        ],
        "authors": [
            {
                "name": "suzan l carmichael",
                "org": ""
            },
            {
                "name": "wei yang",
                "org": ""
            },
            {
                "name": "marcia l feldkamp",
                "org": ""
            },
            {
                "name": "ronald g munger",
                "org": ""
            },
            {
                "name": "anna maria siegariz",
                "org": ""
            },
            {
                "name": "lorenzo d botto",
                "org": ""
            },
            {
                "name": "gary shaw",
                "org": ""
            }
        ],
        "venue": "JAMA Pediatrics",
        "year": 2012
    },
    "fgeWCbRK": {
        "id": "fgeWCbRK",
        "title": "Higher diet quality reduces risks of neural tube defects and orofacial clefts",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "suzan l carmichael",
                "org": ""
            },
            {
                "name": "wei yang",
                "org": ""
            },
            {
                "name": "marcia l feldkamp",
                "org": ""
            },
            {
                "name": "ronald g munger",
                "org": ""
            },
            {
                "name": "anna maria siegariz",
                "org": ""
            },
            {
                "name": "lorenzo d botto",
                "org": ""
            },
            {
                "name": "gary m shaw",
                "org": ""
            }
        ],
        "venue": "JAMA Pediatrics",
        "year": 2012
    },
    "T73pwatV": {
        "id": "T73pwatV",
        "title": "Ambient Air Pollution and Traffic Exposures and Congenital Heart Defects in the San Joaquin Valley of California: Air pollution and congenital heart defects",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "gary m shaw",
                "org": ""
            },
            {
                "name": "fred lurmann",
                "org": ""
            },
            {
                "name": "wei yang",
                "org": ""
            },
            {
                "name": "s katharine hammond",
                "org": ""
            },
            {
                "name": "suzan l carmichael",
                "org": ""
            },
            {
                "name": "ira b tager",
                "org": ""
            },
            {
                "name": "amy padula",
                "org": ""
            }
        ],
        "venue": "Paediatric and Perinatal Epidemiology",
        "year": 2013
    },
    "s8TuZCya": {
        "id": "s8TuZCya",
        "title": "Traffic-related air pollution and selected birth defects in the San Joaquin Valley of California: Air Pollution and Birth Defects",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "gary m shaw",
                "org": ""
            },
            {
                "name": "fred lurmann",
                "org": ""
            },
            {
                "name": "wei yang",
                "org": ""
            },
            {
                "name": "s katharine hammond",
                "org": ""
            },
            {
                "name": "suzan l carmichael",
                "org": ""
            },
            {
                "name": "ira b tager",
                "org": ""
            },
            {
                "name": "amy padula",
                "org": ""
            }
        ],
        "venue": "Birth Defects Research Part A-clinical and Molecular Teratology",
        "year": 2013
    },
    "l1KnsMb7": {
        "id": "l1KnsMb7",
        "title": "One-carbon metabolite levels in mid-pregnancy and risks of conotruncal heart defects: One-Carbon Metabolites And Heart Defects",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "per magne ueland",
                "org": ""
            },
            {
                "name": "edward j lammer",
                "org": ""
            },
            {
                "name": "charlotte a hobbs",
                "org": ""
            },
            {
                "name": "stein emil vollset",
                "org": ""
            },
            {
                "name": "suzan l carmichael",
                "org": ""
            },
            {
                "name": "wei yang",
                "org": ""
            },
            {
                "name": "gary m shaw",
                "org": ""
            }
        ],
        "venue": "Birth Defects Research Part A-clinical and Molecular Teratology",
        "year": 2014
    },
    "H8E9DR0v": {
        "id": "H8E9DR0v",
        "title": "Early pregnancy agricultural pesticide exposures and risk of gastroschisis among offspring in the San Joaquin Valley of California: Gastroschisis and Pesticides",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "gary m shaw",
                "org": ""
            },
            {
                "name": "wei yang",
                "org": ""
            },
            {
                "name": "eric m roberts",
                "org": ""
            },
            {
                "name": "susan e kegley",
                "org": ""
            },
            {
                "name": "amy padula",
                "org": ""
            },
            {
                "name": "paul b english",
                "org": ""
            },
            {
                "name": "suzan l carmichael",
                "org": ""
            }
        ],
        "venue": "Birth Defects Research Part A-clinical and Molecular Teratology",
        "year": 2014
    },
    "nuqb3oTc": {
        "id": "nuqb3oTc",
        "title": "Abstract 16184: Elevated Maternal Glucose Levels During Gestation may Confer Specific Risk for Tetralogy of Fallot",
        "abstract": "Introduction: Clinicians have long observed an association between maternal diabetes and risk of congenital heart disease (CHD) in offspring. Though the clinical diagnoses of Type 2 diabetes or gestational diabetes are strong maternal risk factors, this diagnostic classification captures only a subset of patients with overt hyperglycemia not more subtle abnormalities of glucose or insulin metabolism. We explored the potential risk for two different CHD phenotypes in offspring with with midpregnancy measures of glucose, insulin, and insulin resistance. Hypothesis: We hypothesize that continuous measures of blood analytes related to maternal diabetes will be associated with the risk for two CHD phenotypes tetralogy of Fallot (ToF) and d-Transposition of the Great Arteries (dTGA) which have been recently associated with overt diabetes. Methods: We assembled a prospective cohort of 277 women carrying infants with ToF (n=55), dTGA (n=42), or nonmalformed control infants without CHD (n=180), and measured serum ...",
        "keywords": "",
        "authors": [
            {
                "name": "James R. Priest",
                "org": "Dept of Pediatrics (Cardiology), Stanford Univ Med Cntr, Stanford, CA"
            },
            {
                "name": "Wei Yang",
                "org": "Dept of Pediatrics, Stanford Univ Med Cntr, Stanford, CA"
            },
            {
                "name": "Gerald M. Reaven",
                "org": "Dept of Cardiovascular Medicine, Stanford Univ Med Cntr, Stanford, CA"
            },
            {
                "name": "Joshua W. Knowles",
                "org": "Dept of Cardiovascular Medicine, Stanford Univ Med Cntr, Stanford, CA"
            },
            {
                "name": "Gary M. Shaw",
                "org": "Dept of Pediatrics, Stanford Univ Med Cntr, Stanford, CA"
            }
        ],
        "venue": "Circulation",
        "year": 2015
    },
    "Oi008uUm": {
        "id": "Oi008uUm",
        "title": "Periconceptional changes in weight and risk of delivering offspring with conotruncal heart defects.",
        "abstract": "",
        "keywords": [
            "heart development",
            "nutrition",
            "epidemiology"
        ],
        "authors": [
            {
                "name": "emily carter",
                "org": "stanford university school of medicine"
            },
            {
                "name": "suzan l carmichael",
                "org": "stanford university school of medicine"
            },
            {
                "name": "krista l birnie",
                "org": "stanford university school of medicine"
            },
            {
                "name": "wei yang",
                "org": "stanford university school of medicine"
            },
            {
                "name": "edward j lammer",
                "org": "children s hospital oakland research institute"
            },
            {
                "name": "gary m shaw",
                "org": "stanford university school of medicine"
            }
        ],
        "venue": "Birth Defects Research Part A-clinical and Molecular Teratology",
        "year": 2015
    },
    "4VluKS0H": {
        "id": "4VluKS0H",
        "title": "Failed endotracheal intubation and adverse outcomes among extremely low birth weight infants.",
        "abstract": "To quantify the importance of successful endotracheal intubation on the first attempt among extremely low birth weight (ELBW) infants who require resuscitation after delivery.A retrospective chart review was conducted for all ELBW infants ⩽1000 g born between January 2007 and May 2014 at a level IV neonatal intensive care unit. Infants were included if intubation was attempted during the first 5 min of life or if intubation was attempted during the first 10 min of life with heart rate <100. The primary outcome was death or neurodevelopmental impairment. The association between successful intubation on the first attempt and the primary outcome was assessed using multivariable logistic regression with adjustment for birth weight, gestational age, gender and antenatal steroids.The study sample included 88 ELBW infants. Forty percent were intubated on the first attempt and 60% required multiple intubation attempts. Death or neurodevelopmental impairment occurred in 29% of infants intubated on the first attempt, compared with 53% of infants that required multiple attempts, adjusted odds ratio 0.4 (95% confidence interval 0.1 to 1.0), P<0.05.Successful intubation on the first attempt is associated with improved neurodevelopmental outcomes among ELBW infants. This study confirms the importance of rapid establishment of a stable airway in ELBW infants requiring resuscitation after birth and has implications for personnel selection and role assignment in the delivery room.Journal of Perinatology advance online publication, 5 November 2015; doi:10.1038/jp.2015.158.",
        "keywords": [
            "neonatology"
        ],
        "authors": [
            {
                "name": "matthew b wallenstein",
                "org": "Department of Pediatrics, Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, Stanford, CA, USA."
            },
            {
                "name": "krista l birnie",
                "org": "Department of Pediatrics, Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, Stanford, CA, USA."
            },
            {
                "name": "yassar h arain",
                "org": "Department of Pediatrics, Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, Stanford, CA, USA."
            },
            {
                "name": "wei yang",
                "org": "Department of Pediatrics, Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, Stanford, CA, USA."
            },
            {
                "name": "nobuhiro yamada",
                "org": "Department of Pediatrics, Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, Stanford, CA, USA."
            },
            {
                "name": "lynne c huffman",
                "org": "Department of Pediatrics, Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, Stanford, CA, USA."
            },
            {
                "name": "J P Palma",
                "org": "Department of Pediatrics, Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, Stanford, CA, USA."
            },
            {
                "name": "valerie y chock",
                "org": "Department of Pediatrics, Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, Stanford, CA, USA."
            },
            {
                "name": "gary m shaw",
                "org": "Department of Pediatrics, Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, Stanford, CA, USA."
            },
            {
                "name": "david k stevenson",
                "org": "Department of Pediatrics, Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, Stanford, CA, USA."
            }
        ],
        "venue": "Journal of perinatology : official journal of the California Perinatal Association",
        "year": 2015
    },
    "kEzS35JX": {
        "id": "kEzS35JX",
        "title": "Residential agricultural pesticide exposures and risks of selected birth defects among offspring in the San Joaquin Valley of California",
        "abstract": "",
        "keywords": [
            "pesticides"
        ],
        "authors": [
            {
                "name": "suzan l carmichael",
                "org": "stanford university school of medicine"
            },
            {
                "name": "wei yang",
                "org": "stanford university school of medicine"
            },
            {
                "name": "eric roberts",
                "org": ""
            },
            {
                "name": "susan e kegley",
                "org": "university of california berkeley"
            },
            {
                "name": "timothy j brown",
                "org": "university of california berkeley"
            },
            {
                "name": "paul b english",
                "org": "california department of public health"
            },
            {
                "name": "edward j lammer",
                "org": "children s hospital oakland"
            },
            {
                "name": "gary m shaw",
                "org": "stanford university school of medicine"
            }
        ],
        "venue": "Birth Defects Research Part A-clinical and Molecular Teratology",
        "year": 2015
    },
    "a1YENxGy": {
        "id": "a1YENxGy",
        "title": "Air Pollution, Neighbourhood Socioeconomic Factors, and Neural Tube Defects in the San Joaquin Valley of California",
        "abstract": "",
        "keywords": [
            "air pollution",
            "neighbourhood",
            "socioeconomic status"
        ],
        "authors": [
            {
                "name": "amy padula",
                "org": "stanford university"
            },
            {
                "name": "wei yang",
                "org": "stanford university"
            },
            {
                "name": "suzan l carmichael",
                "org": "stanford university"
            },
            {
                "name": "ira b tager",
                "org": "university of california"
            },
            {
                "name": "fred lurmann",
                "org": ""
            },
            {
                "name": "s katharine hammond",
                "org": "university of california"
            },
            {
                "name": "gary m shaw",
                "org": "stanford university"
            }
        ],
        "venue": "Paediatric and Perinatal Epidemiology",
        "year": 2015
    },
    "9G5klTD9": {
        "id": "9G5klTD9",
        "title": "Inflammatory biomarkers and spontaneous preterm birth among obese women",
        "abstract": "In this pilot study, we identified three serum biomarkers indicative of inflammation to be associated with spontaneous preterm birth among obese women: sVEGFR3, sIL-2RA and sTNFR1.",
        "keywords": [
            "Inflammation",
            "inflammatory markers",
            "obesity",
            "preterm birth",
            "soluble interleukin-2 receptor alpha-chain",
            "soluble tumor necrosis factor receptor-1",
            "vascular endothelial growth factor",
            "vascular endothelial growth factor receptor-3"
        ],
        "authors": [
            {
                "name": "matthew b wallenstein",
                "org": ""
            },
            {
                "name": "laura l jelliffepawlowski",
                "org": ""
            },
            {
                "name": "wei yang",
                "org": ""
            },
            {
                "name": "suzan l carmichael",
                "org": ""
            },
            {
                "name": "david k stevenson",
                "org": ""
            },
            {
                "name": "kelli k ryckman",
                "org": ""
            },
            {
                "name": "gary m shaw",
                "org": ""
            }
        ],
        "venue": "The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians",
        "year": 2015
    },
    "bg86fiu4": {
        "id": "bg86fiu4",
        "title": "Elevated body mass index and decreased diet quality among women and risk of birth defects in their offspring.",
        "abstract": "",
        "keywords": [
            "obesity",
            "nutrition"
        ],
        "authors": [
            {
                "name": "suzan l carmichael",
                "org": "stanford university"
            },
            {
                "name": "wei yang",
                "org": "stanford university"
            },
            {
                "name": "suzanne m gilboa",
                "org": "centers for disease control and prevention"
            },
            {
                "name": "elizabeth c ailes",
                "org": "centers for disease control and prevention"
            },
            {
                "name": "armando g correa",
                "org": "university of mississippi medical center"
            },
            {
                "name": "lorenzo d botto",
                "org": "university of utah school of medicine"
            },
            {
                "name": "marcia l feldkamp",
                "org": "university of utah school of medicine"
            },
            {
                "name": "gary m shaw",
                "org": "stanford university"
            }
        ],
        "venue": "Birth Defects Research Part A-clinical and Molecular Teratology",
        "year": 2015
    },
    "ymuLxAs5": {
        "id": "ymuLxAs5",
        "title": "Maternal Midpregnancy Glucose Levels and Risk of Congenital Heart Disease in Offspring",
        "abstract": "",
        "keywords": [
            "offspring",
            "insulin",
            "risk factors"
        ],
        "authors": [
            {
                "name": "james r priest",
                "org": "stanford university"
            },
            {
                "name": "wei yang",
                "org": "stanford university school of medicine"
            },
            {
                "name": "gerald m reaven",
                "org": "stanford university"
            },
            {
                "name": "joshua w knowles",
                "org": "stanford university"
            },
            {
                "name": "gary m shaw",
                "org": "stanford university school of medicine"
            }
        ],
        "venue": "JAMA Pediatrics",
        "year": 2015
    },
    "Uqbx60il": {
        "id": "Uqbx60il",
        "title": "Heme oxygenase‐1 promoter polymorphisms and risk of spina bifida",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "kazumichi fujioka",
                "org": "stanford university school of medicine"
            },
            {
                "name": "wei yang",
                "org": "stanford university school of medicine"
            },
            {
                "name": "matthew b wallenstein",
                "org": "stanford university school of medicine"
            },
            {
                "name": "hui zhao",
                "org": "stanford university school of medicine"
            },
            {
                "name": "ronald j wong",
                "org": "stanford university school of medicine"
            },
            {
                "name": "david k stevenson",
                "org": "stanford university school of medicine"
            },
            {
                "name": "gary m shaw",
                "org": "stanford university school of medicine"
            }
        ],
        "venue": "Birth Defects Research Part A-clinical and Molecular Teratology",
        "year": 2015
    },
    "eAvpHYoV": {
        "id": "eAvpHYoV",
        "title": "Abstract 17229: First Trimester Elevated Serum Glucose Values Are Associated With Congenital Heart Disease in the Offspring",
        "abstract": "Introduction: Maternal diabetes mellitus (DM) during pregnancy is a well known and prevalent risk factor for congenital heart disease (CHD) in offspring. In mothers without DM, we recently observed an association between elevated serum glucose values measured in the second trimester and the risk for CHDs in offspring. Hypothesis: As cardiac development largely occurs during weeks 4-12 of gestation, we hypothesized that measurements of glucose metabolism during early pregnancy, i.e., well before the second trimester, would be associated with risk for CHD. Methods: We performed a multi-institutional retrospective case-control study from a population-based cohort of 19,107 pregnant women from Stanford Healthcare and Geisinger Health System comparing liveborn infants with CHD to infants without CHD (Table 1). Multivariable logistic regression analysis was used to investigate the association between 1) mother’s plasma glucose values from 4 weeks prior to conception to 15 weeks and 2) the 1hour glucose toleranc...",
        "keywords": "",
        "authors": [
            {
                "name": "Emmi Helle",
                "org": ""
            },
            {
                "name": "Preston S Biegley",
                "org": ""
            },
            {
                "name": "Joshua W Knowles",
                "org": ""
            },
            {
                "name": "Joseph B Leader",
                "org": ""
            },
            {
                "name": "Sarah A Pendergrass",
                "org": ""
            },
            {
                "name": "Gary Reaven",
                "org": ""
            },
            {
                "name": "Marylyn D Ritchie",
                "org": ""
            },
            {
                "name": "Gary M Shaw",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "James R Priest",
                "org": ""
            }
        ],
        "venue": "Circulation",
        "year": 2016
    },
    "jwBOncrD": {
        "id": "jwBOncrD",
        "title": "Sequence variation in folate pathway genes and risks of human cleft lip with or without cleft palate",
        "abstract": "In an effort to comprehensively interrogate genetic variation in the folate pathway for risk of cleft lip with or without cleft palate (CLP), we evaluated 504 common and rare variants in 35 folate-related genes in a panel of 330 infants with CLP and 367 non-malformed controls. Odds ratios (OR) with 95% confidence intervals were computed for common genotypes. A Case-Control Difference metric was calculated for rare variants to highlight differentially occurring alleles. Interactions between variants and a maternal folate intake variable were also evaluated. In gene-only results, significant odds ratios were observed for multiple variants in the BHMT/BHMT2/DMGDH gene cluster, particularly in Hispanic infants. Also in this cluster, rare variant analysis highlighted a substantial case-control difference in BHMT rs60340837 (synonymous Y284Y). In Hispanics, the ALDH1L1 I812V variant (rs4646750) was the most significant risk allele: OR = 3.8 (95%CI = 1.6-9.2) when heterozygous. In non-Hispanic white infants, we observed significant risk for AHCYL2 rs1095423 (homozygous OR = 3.0, 95%CI 1.1-7.8) and the 68 bp CBS insertion (c.844ins68; heterozygous OR = 2.4, 95%CI = 1.1-5.3). Rare variant analysis in this group revealed case-control differences in MTRR and several other methionine cycle genes, a process implicated previously in clefting risk. In women with low folate intake specifically, increased risks were observed for CBS rs2851391 (OR = 3.6, 95%CI = 1.3-9.6) and the R259P nonsynonymous variant of TCN2 (rs1801198; OR = 2.8, 95%CI = 1.2-6.3). This comprehensive study provides further direction on candidate loci to help disentangle the folate-related developmental phenomena in human clefting risk. © 2016 Wiley Periodicals, Inc.",
        "keywords": "",
        "authors": [
            {
                "name": "Nicholas J. Marini",
                "org": "Department of Molecular and Cellular Biology, California Institute for Quantitative Biosciences, University of California, Berkeley, California"
            },
            {
                "name": "Wei Yang",
                "org": "Department of Pediatrics, Stanford University School of Medicine, Stanford, California"
            },
            {
                "name": "Kripa Asrani",
                "org": "Department of Molecular and Cellular Biology, California Institute for Quantitative Biosciences, University of California, Berkeley, California"
            },
            {
                "name": "John S. Witte",
                "org": "Department of Epidemiology and Biostatistics and Institute of Human Genetics, University of California, San Francisco, California"
            },
            {
                "name": "Jasper Rine",
                "org": "Department of Molecular and Cellular Biology, California Institute for Quantitative Biosciences, University of California, Berkeley, California"
            },
            {
                "name": "Edward J. Lammer",
                "org": "UCSF Benioff Children's Hospital Oakland Oakland California"
            },
            {
                "name": "Gary M. Shaw",
                "org": "Department of Pediatrics, Stanford University School of Medicine, Stanford, California"
            }
        ],
        "venue": "American Journal of Medical Genetics Part A",
        "year": 2016
    },
    "GAPSiRkd": {
        "id": "GAPSiRkd",
        "title": "Folic acid fortification and prevalences of neural tube defects, orofacial clefts, and gastroschisis in California, 1989 to 2010.",
        "abstract": "We observed a slower decline in prevalence of NTDs, an emergence of a decline in orofacial clefts, and a slower increase in gastroschisis, during the postfortification period in central California, relative to the prefortification period. Birth Defects Research (Part A), 2016. © 2016 Wiley Periodicals, Inc. Birth Defects Research (Part A) 106:1032-1041, 2016. © 2016 Wiley Periodicals, Inc.",
        "keywords": [
            "folic acid",
            "food",
            "food supply",
            "fortified",
            "gastroschisis",
            "neural tube defects",
            "orofacial clefts",
            "pregnancy"
        ],
        "authors": [
            {
                "name": "Wei Yang",
                "org": "Department of Pediatrics, Division of Neonatology, Stanford University School of Medicine, Stanford, California, USA."
            },
            {
                "name": "Suzan L Carmichael",
                "org": "Department of Pediatrics, Division of Neonatology, Stanford University School of Medicine, Stanford, California, USA."
            },
            {
                "name": "Gary M Shaw",
                "org": "Department of Pediatrics, Division of Neonatology, Stanford University School of Medicine, Stanford, California, USA."
            }
        ],
        "venue": "Birth defects research. Part A, Clinical and molecular teratology",
        "year": 2016
    },
    "YDa3vaQf": {
        "id": "YDa3vaQf",
        "title": "Selected birth defects among males following the United States terrorist attacks of 11 September 2001.",
        "abstract": "The terrorist attacks of 11 September 2001 (hereafter referred to as 9/11) preceded an increase in male fetal deaths and reduced male live births among exposed gestational cohorts across several geographic locations in the United States, including California. We analyze whether the extreme stressor of 9/11 may have selected against frail males in utero by testing if the prevalence of male births with selected defects in California fell among cohorts exposed to the stressor during gestation.We used data from the California Birth Defects Monitoring Program from July 1985 to January 2004 (223 conception cohorts). We included six birth defects that as a group of phenotypes disproportionately affect males. We applied time-series methods and defined as \"exposed to 9/11\" the cohorts conceived in February, March, April, May, June, July, and August 2001.Three of the seven monthly conception cohorts exposed to 9/11 in utero show lower than expected odds of live born males with the studied defects: February 2001 (odds ratio [OR] = 0.39; 95% confidence interval [CI], 0.21-0.71), May 2001 (OR = 0.36; 95% CI, 0.16-0.81), and August 2001 (OR = 0.51; 95% CI, 0.28-0.93).The population-wide stressor of 9/11 precedes a reduction in the risk of live born males with selected birth defects. Our analysis contributes to the understanding of adaptation to stress among pregnant women exposed to large and unexpected ambient stressors. Results further support the notion that the prevalence of live born defects may reflect temporal variation in cohort selection in utero against frail males. Birth Defects Research, 2017.© 2017 Wiley Periodicals, Inc.",
        "keywords": [
            "September 11th",
            "ambient stressors",
            "birth defects",
            "conception cohorts",
            "time series"
        ],
        "authors": [
            {
                "name": "Parvati Singh",
                "org": "University of California Irvine, Program in Public Health, Irvine, California."
            },
            {
                "name": "Wei Yang",
                "org": "Stanford University, School of Medicine, Stanford, California."
            },
            {
                "name": "Gary M Shaw",
                "org": "Stanford University, School of Medicine, Stanford, California."
            },
            {
                "name": "Ralph Catalano",
                "org": "University of California Berkeley, School of Public Health, Berkeley, California."
            },
            {
                "name": "Tim A Bruckner",
                "org": "University of California Irvine, Program in Public Health, Irvine, California."
            }
        ],
        "venue": "Birth defects research",
        "year": 2017
    },
    "tj3eJnKk": {
        "id": "tj3eJnKk",
        "title": "First Trimester Plasma Glucose Values in Women without Diabetes are Associated with Risk for Congenital Heart Disease in Offspring.",
        "abstract": "In a retrospective study of 19 171 mother-child dyads, elevated random plasma glucose values during early pregnancy were directly correlated with increased risk for congenital heart disease in offspring. Plasma glucose levels proximal to the period of cardiac development may represent a modifiable risk factor for congenital heart disease in expectant mothers without diabetes.",
        "keywords": [
            "congenital heart disease",
            "congenital malformation",
            "diabetes",
            "oral glucose tolerance test",
            "plasma glucose"
        ],
        "authors": [
            {
                "name": "Emmi I T Helle",
                "org": "Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA; Children's Hospital, University of Helsinki, Helsinki, Finland."
            },
            {
                "name": "Preston Biegley",
                "org": "Department of Biomedical and Translational Informatics, Geisinger Health System, Danville, PA."
            },
            {
                "name": "Joshua W Knowles",
                "org": "Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA."
            },
            {
                "name": "Joseph B Leader",
                "org": "Department of Biomedical and Translational Informatics, Geisinger Health System, Danville, PA."
            },
            {
                "name": "Sarah Pendergrass",
                "org": "Department of Biomedical and Translational Informatics, Geisinger Health System, Danville, PA."
            },
            {
                "name": "Wei Yang",
                "org": "Department of Pediatrics, Stanford University School of Medicine, Stanford, CA."
            },
            {
                "name": "Gerald R Reaven",
                "org": "Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA."
            },
            {
                "name": "Gary M Shaw",
                "org": "Department of Pediatrics, Stanford University School of Medicine, Stanford, CA."
            },
            {
                "name": "Marylyn Ritchie",
                "org": "Department of Biomedical and Translational Informatics, Geisinger Health System, Danville, PA."
            },
            {
                "name": "James R Priest",
                "org": "Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA; Division of Pediatric Cardiology, Stanford University School of Medicine, Stanford, CA."
            }
        ],
        "venue": "The Journal of pediatrics",
        "year": 2017
    },
    "T5NDXBdM": {
        "id": "T5NDXBdM",
        "title": "Cohort Variation in Selection During Pregnancy and Risk of Selected Birth Defects Among Males.",
        "abstract": "Our findings among males indicate that variation in the strength of selectivity in utero accounts for a portion of observed cohort differences in morbidity due to birth defects. These findings suggest that \"revealed prevalence\" of morbidity across birth cohorts varies, at least in part, from selective loss in utero. See video abstract at, http://links.lww.com/EDE/B209.",
        "keywords": "",
        "authors": [
            {
                "name": "Tim A Bruckner",
                "org": "From the aProgram in Public Health, University of California, Irvine, Irvine, CA; bSchool of Public Health, University of California, Berkeley, Berkeley, CA; and cDivision of Neonatology, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA."
            },
            {
                "name": "Deborah Karasek",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Gary M Shaw",
                "org": ""
            },
            {
                "name": "Ralph A Catalano",
                "org": ""
            }
        ],
        "venue": "Epidemiology (Cambridge, Mass.)",
        "year": 2017
    },
    "Xl3dtqdq": {
        "id": "Xl3dtqdq",
        "title": "Residential agricultural pesticide exposures and risks of preeclampsia.",
        "abstract": "We investigated risks of preeclampsia phenotypes from potential residential pesticide exposures, including 543 individual chemicals and 69 physicochemical groupings that were applied in the San Joaquin Valley of California during the study period, 1998-2011. The study population was derived from birth certificate data linked with Office of Statewide Health Planning and Development maternal and infant hospital discharge data. The following numbers of women with preeclampsia phenotypes were identified: 1045 with superimposed (pre-existing hypertension with preeclampsia) preeclampsia (265 with gestational weeks 20-31 and 780 with gestational weeks 32-36); 3471 with severe preeclampsia (824 with gestational weeks 20-31 and 2647 with gestational weeks 32-36); and 2780 with mild preeclampsia (207 with gestational weeks 20-31 and 2573 with gestational weeks 32-36). The reference population for these groups was 197,461 women who did not have diabetes (gestational or pre-existing), did not have any hypertensive disorder, and who delivered at 37 weeks or later. The frequency of any exposure was lower or about the same in each preeclampsia case group (further delineated by gestational age), and month time period, relative to the frequency in reference population controls. Nearly all odds ratios were below 1.0 for these any vs no exposure comparisons. This study showed a general lack of increased risks between a range of agriculture pesticide exposures near women's residences and various preeclampsia phenotypes.",
        "keywords": [
            "Endocrine disruptors",
            "Environment",
            "Hypertension",
            "Pesticides",
            "Pregnancy"
        ],
        "authors": [
            {
                "name": "Gary M Shaw",
                "org": "March of Dimes Prematurity Research Center at Stanford University, Department of Pediatrics, Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address: gmshaw@stanford.edu."
            },
            {
                "name": "Wei Yang",
                "org": "March of Dimes Prematurity Research Center at Stanford University, Department of Pediatrics, Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA."
            },
            {
                "name": "Eric M Roberts",
                "org": "Public Health Institute, Oakland, CA 94607, USA."
            },
            {
                "name": "Nima Aghaeepour",
                "org": "Stanford University, Department of Anesthesiology, Perioperative and Pain Medicine, Stanford, CA 94305, USA."
            },
            {
                "name": "Jonathan A Mayo",
                "org": "March of Dimes Prematurity Research Center at Stanford University, Department of Pediatrics, Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA."
            },
            {
                "name": "Kari A Weber",
                "org": "March of Dimes Prematurity Research Center at Stanford University, Department of Pediatrics, Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA."
            },
            {
                "name": "Ivana Maric",
                "org": "March of Dimes Prematurity Research Center at Stanford University, Department of Pediatrics, Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA."
            },
            {
                "name": "Suzan L Carmichael",
                "org": "March of Dimes Prematurity Research Center at Stanford University, Department of Pediatrics, Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA."
            },
            {
                "name": "Virginia D Winn",
                "org": "Stanford University, Department of Obstetrics and Gynecology, Stanford, CA 94305, USA."
            },
            {
                "name": "David K Stevenson",
                "org": "March of Dimes Prematurity Research Center at Stanford University, Department of Pediatrics, Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA."
            },
            {
                "name": "Paul B English",
                "org": "California Department of Public Health, Richmond, CA 94804, USA."
            }
        ],
        "venue": "Environmental research",
        "year": 2018
    },
    "N8UykJ8s": {
        "id": "N8UykJ8s",
        "title": "Nutrient intake in women before conception and risks of anophthalmia and microphthalmia in their offspring.",
        "abstract": "In this expanded analysis, we observed associations for a few nutrients, specifically forms of vitamin A. However, the heterogeneity of results by form and vitamin use necessitates further inquiry.",
        "keywords": [
            "anophthalmia",
            "diet",
            "microphthalmia",
            "nutrition",
            "vitamin supplements"
        ],
        "authors": [
            {
                "name": "Kari A Weber",
                "org": "Division of Neonatal and Developmental Medicine, Department of Pediatrics, Stanford University School of Medicine, Stanford, California."
            },
            {
                "name": "Wei Yang",
                "org": "Division of Neonatal and Developmental Medicine, Department of Pediatrics, Stanford University School of Medicine, Stanford, California."
            },
            {
                "name": "Suzan L Carmichael",
                "org": "Division of Neonatal and Developmental Medicine, Department of Pediatrics, Stanford University School of Medicine, Stanford, California."
            },
            {
                "name": "Gary M Shaw",
                "org": "Division of Neonatal and Developmental Medicine, Department of Pediatrics, Stanford University School of Medicine, Stanford, California."
            },
            {
                "name": "",
                "org": ""
            }
        ],
        "venue": "Birth defects research",
        "year": 2018
    },
    "2nDjjOHM": {
        "id": "2nDjjOHM",
        "title": "A cumulant-based 2D-RAKE receiver for CDMA system over frequency-selective fading channels",
        "abstract": "Generally, the conventional 2D-RAKE receivers are based on the second-order statistics while assuming perfect array conditions. However, the sensor response, location uncertainty, and the use of sample statistics can severely degrade the performance of second-order statistics processing. In this paper a cumulant-based 2D-RAKE receiver for synchronous CDMA system with decorrelator is presented. Employing cumulant-based signal processing technique the proposed 2D-RAKE receiver is blind and demonstrates excellent performance.",
        "keywords": [
            "decorrelator",
            "location uncertainty",
            "second-order statistics",
            "radiofrequency interference",
            "statistics",
            "frequency-selective fading channels",
            "cdma system",
            "fading channels",
            "antenna arrays",
            "array signal processing",
            "code division multiple access",
            "blind receiver",
            "cumulant-based signal processing technique",
            "radio receivers",
            "multiuser detection",
            "sensor response",
            "2d-rake receiver",
            "interference",
            "cumulant",
            "code division multiplexing",
            "rake receiver",
            "degradation",
            "decorrelation",
            "signal processing"
        ],
        "authors": [
            {
                "name": "Wei Yang",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            },
            {
                "name": "Zhenhui Tan",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            }
        ],
        "venue": "Vehicular Technology Conference, 2003. VTC 2003-Spring. The 57th IEEE Semiannual",
        "year": 2003
    },
    "1fVa8ZCb": {
        "id": "1fVa8ZCb",
        "title": "Analysis of a cumulant-based 2D-Rake receiver for CDMA system over frequency-selective fading channels",
        "abstract": "The conventional 2D-Rake receivers for code-division multiple access (CDMA) system over frequency-selective fading channels are generally based on the second-order statistics while assuming perfect array conditions. However, the sensor response, location uncertainty, and the use of sample statistics can severely degrade the performance of second-order statistics processing. And in practical application, it is impossible to calibrate the array frequently. In this paper a cumulant-based 2D-Rake receiver for synchronous CDMA system with decorrelator is presented. Decorrelating is a multi-user detection approach that not only provides a fundamental solution to the mutual interference problem in CDMA communications but also makes it convenient for the decoupled signal to be processed spatially and temporally. High-order signal processing has some inherent advantages over that of second-order. Employing second-order statistics it is impossible to estimate source steering vector blindly, while employing higher than second-order cumulants, this purpose can be achieved. The performance analysis shows that employing cumulant-based signal processing technique the proposed 2D-Rake receiver is blind and demonstrates excellent performance.",
        "keywords": [
            "2D-Rake receiver",
            "Code-division multiple access (CDMA)",
            "Cumulant"
        ],
        "authors": [
            {
                "name": "Wei Yang",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            },
            {
                "name": "Shixin Cheng",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            }
        ],
        "venue": "Academic Journal of Xi'an Jiaotong University",
        "year": 2003
    },
    "vA20Vgu1": {
        "id": "vA20Vgu1",
        "title": "A matched filter bank based DOA estimation for asynchronous multipath CDMA channels",
        "abstract": "In this paper, a Direction Of Arrival (DOA) estimation algorithm is proposed for multiuser signals through uplink asynchronous multipath Code Division Multiple Access (CDMA) channels. The algorithm is based directly on the correlation matrices of matched filter bank outputs of desired user’s multipath signals and it does not require that the elements of base station antenna array outnumber the multipath signals, which is necessary for the conventional sub-space based direction-finding algorithm. Simulation results show that the proposed algorithm estimates the DOA of multipath signals effectively and acceptably. The proposed algorithm has the prominent advantages of low complexity, simpleness and practicality, which make it much more suitable for practical application.",
        "keywords": [
            "base station",
            "code division multiple access",
            "antenna array",
            "direction of arrival",
            "matched filter"
        ],
        "authors": [
            {
                "name": "wei yang",
                "org": "beijing jiaotong university"
            },
            {
                "name": "junshi chen",
                "org": "beijing jiaotong university"
            },
            {
                "name": "zhenhui tan",
                "org": "beijing jiaotong university"
            },
            {
                "name": "takis mathiopoulos",
                "org": "university of british columbia"
            }
        ],
        "venue": "Journal of Electronics (china)",
        "year": 2005
    },
    "ImoIFNa8": {
        "id": "ImoIFNa8",
        "title": "Analysis and Solution of Routing Security in Mobile Ad hoc Network",
        "abstract": "Mobile Ad hoc network is a self-organizing multi-hop wireless network. The characteristics make it face much more security challenges than the existing networks. The routing security plays a key role in the security of the whole network. Based on the description of the main routing protocols and their characteristics in mobile Ad hoc network, some routing security drawbacks such as blackhole, DoS attack are analyzed in depth. Several security solutions for the main types of mobile Ad hoc routing protocols are discussed in details. Two kinds of improved protocols for distance vector routing protocols are presented, in which the one-way hash chain is used. Feasibility of a method to secure source routing protocol is analyzed. Further research directions concerning the security of mobile Ad hoc routing protocols are given.",
        "keywords": [
            "DSR(Dynamic Source Routing Protocol)",
            "DSDV(Destination Sequenced Distance Vector Routing Protocol)",
            "mobile ad hoc network (MANET)",
            "AODV(Ad hoc On-demand Distance Vector Routing Protocol)",
            "routing protocol"
        ],
        "authors": [
            {
                "name": "FU Fang",
                "org": "1 Modern Telecommunication Institute, Beijing Jiaotong University,Beijing ,China ;2 State Key Laboratory of Information Security, Graduate School, Chinese Academy of Sciences,Beijing ,China"
            },
            {
                "name": "YANG Wei",
                "org": "1 Modern Telecommunication Institute, Beijing Jiaotong University,Beijing ,China ;2 State Key Laboratory of Information Security, Graduate School, Chinese Academy of Sciences,Beijing ,China"
            },
            {
                "name": "ZHANG Si-dong",
                "org": "1 Modern Telecommunication Institute, Beijing Jiaotong University,Beijing ,China "
            }
        ],
        "venue": "China Safety Science Journal",
        "year": 2005
    },
    "C0wZL86q": {
        "id": "C0wZL86q",
        "title": "Frequency selection for the wireless communication in coal mine underground based on the hybrid waveguide theory",
        "abstract": "Based on the theory of hybrid waveguide, the paper analyses and simulates the loss of radio propagating in rectangular tunnel of the coalmine underground The values of the simulation are agreed with what measured practically in other papers. At last, it deduces the most advisable frequency point for the wireless communication system in the coalmine underground so as to build the strong basement for the new generation wireless information system for the coalmine. © 2005 IEEE.",
        "keywords": [
            "coalmine underground",
            "frequency selection",
            "hybrid waveguide",
            "radio loss",
            "information system",
            "mining",
            "wireless communication",
            "coal mining",
            "waveguide theory",
            "radio propagation"
        ],
        "authors": [
            {
                "name": "Hongxian Tian",
                "org": "China University of Mining Technology(China University of Mining and Technology,China Univ. of Mining and Technol.),Beijing,China"
            },
            {
                "name": "Wei Yang",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "GongXun Yang",
                "org": "China University of Mining Technology(China University of Mining and Technology,China Univ. of Mining and Technol.),Beijing,China"
            }
        ],
        "venue": "MAPE2005: IEEE 2005 International Symposium on Microwave, Antenna, Propagation and EMC Technologies for Wireless Communications, Proceedings",
        "year": 2005
    },
    "TneIIUvj": {
        "id": "TneIIUvj",
        "title": "Capacity improvement of multicarrier DS-CDMA system with antenna array",
        "abstract": "An antenna array based base station receiver for multicarrier Direct Sequence Code Division Multiple Access (DS-CDMA) system\n is proposed. The main advantage of the receiver is that the spatial diversity is achieved by combining signals of array elements.\n Based on the detailed analysis of multiuser interference and noise characteristics, the performance of the proposed receiver\n is analyzed. Theoretical analysis shows significant performance improvement in terms of system capacity due to the use of\n antenna arrays compared with the conventional single antenna multicarrier DS-CDMA approach. Simulation results confirm the\n theoretical analysis.",
        "keywords": [
            "Multicarrier",
            "Antenna array",
            "ds-cdma",
            "antenna array",
            "space-time signal processing",
            "Space-time signal processing",
            "DS-CDMA",
            "multicarrier"
        ],
        "authors": [
            {
                "name": "Wei Yang",
                "org": "Beijing Jiaotong University School of Electronics and Information Engineering Beijing 100044 China Beijing 100044 China"
            },
            {
                "name": "Shiming Li",
                "org": "Beijing Jiaotong University School of Electronics and Information Engineering Beijing 100044 China Beijing 100044 China"
            },
            {
                "name": "Zhenhui Tan",
                "org": "Beijing Jiaotong University School of Electronics and Information Engineering Beijing 100044 China Beijing 100044 China"
            },
            {
                "name": "Shixin Cheng",
                "org": "Southeast University National Mobile Communications Research Laboratory Nanjing 210096 China Nanjing 210096 China"
            }
        ],
        "venue": "Journal of Electronics (china)",
        "year": 2006
    },
    "L9fSMlPX": {
        "id": "L9fSMlPX",
        "title": "DOA estimation for MC-CDMA system with antenna array",
        "abstract": "In this paper, a Direction of Arrival (DOA) estimation algorithm is proposed for uplink MC-CDMA system with antenna array. By utilizing the orthogonality of spreading codes and frequency diversity of MC-CDMA the users' signals are separated and enhanced, and the multiple access interference (MAI) is suppressed. After that the conventional subspace based DOA estimation is applied to estimate the DOAs of users' signals. Simulation results show the efficiency of the proposed algorithm. © 2007 IEEE.",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Dezhen Zhang",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            },
            {
                "name": "Shuo Yang",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            },
            {
                "name": "Wei Yang",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            }
        ],
        "venue": "IEEE 2007 International Symposium on Microwave, Antenna, Propagation and EMC Technologies for Wireless Communications, MAPE",
        "year": 2006
    },
    "jCP2xXcb": {
        "id": "jCP2xXcb",
        "title": "System structure and technologies for mine wireless transfer comprehensive safety monitoring and measuring information system",
        "abstract": "A system structure on a mine wireless transfer comprehensive safety monitoring information system was set up.The paper provided that a wide frequency wireless transmission wireless sensor network technology should be the ideal and effective method to set up a mine wireless safety monitoring and measuring information system.The paper provided the theory and key technologies related.",
        "keywords": [
            "information system",
            "wireless sensor network",
            "wireless safety monitoring and measuring"
        ],
        "authors": [
            {
                "name": "YANG Wei",
                "org": "School of Electric Information Engineering,Beijing Jiaotong University,Beijing ,China;National Key Laboratory of Fire Disaster Science,China University of Science and Technology,Hefei ,China"
            },
            {
                "name": "QIAO Hua",
                "org": "Tiandi Science and Technology Company Ltd.,Beijing ,China"
            }
        ],
        "venue": "Coal Science and Technology",
        "year": 2006
    },
    "huGwcYgm": {
        "id": "huGwcYgm",
        "title": "An improved DOA estimation algorithm for asynchronous multipath CDMA system",
        "abstract": "This paper proposes an improved Direction Of Arrival(DOA) estimation algorithm for asynchronous multipath Code Division Multiple\n Access(CDMA) system. The algorithm is based on the correlation matrices of outputs of decorrelator, which is a Multi-User\n Detection(MUD) approach, one of the key techniques for CDMA system. Through decorrelating processing, the desired user’s mulipath\n signals can be resolved and all the other resolved multipath signal interference is eliminated. So the proposed algorithm\n is expected to perform much better than algorithm such as that based directly on the Matched Filter(MF) bank outputs. Simulation\n results confirm this. While the improved algorithm performs better and better as Signal-to-Noise Ratio(SNR) increases, the\n performance of algorithm based directly on the MF bank outputs can not be improved.",
        "keywords": [
            "decorrelating",
            "Code Division Multiple Access(CDMA)",
            "direction of arrivaldoa estimation",
            "Direction Of Arrival(DOA) estimation",
            "Asynchronous multipath channel",
            "asynchronous multipath channel",
            "code division multiple accesscdma",
            "Decorrelating"
        ],
        "authors": [
            {
                "name": "Wei Yang",
                "org": "Beijing Jiaotong University School of Electronics and Info. Eng. Beijing 100044 China"
            },
            {
                "name": "Junshi Chen",
                "org": "Beijing Jiaotong University School of Electronics and Info. Eng. Beijing 100044 China"
            },
            {
                "name": "Zhenhui Tan",
                "org": "Beijing Jiaotong University School of Electronics and Info. Eng. Beijing 100044 China"
            },
            {
                "name": "Takis Mathiopoulos",
                "org": "Univ. of British Columbia Dept of Electrical and Computer Eng. Vancouver BC V6T 1Z4 Canada"
            }
        ],
        "venue": "Journal of Electronics (china)",
        "year": 2006
    },
    "YYHTGLZX": {
        "id": "YYHTGLZX",
        "title": "The performance of MT-CDMA system in the presence of carrier frequency offset",
        "abstract": "In this letter, the sensitivity of an uplink Multi-Tone Code-Division Multiple Access (MT-CDMA) system to the Carrier Frequency\n Offset (CFO) is investigated. The analytical expression for the Bit Error Rate (BER) of uplink MT-CDMA in the presence of\n CFO is derived in a multipath Rayleigh fading channel which is verified through simulations. Both Maximal Ratio Combining\n (MRC) and Equal Gain Combining (EGC) are considered in combining multipath signals in the analysis. It is found that the BER\n performance can be improved with the number of multipath increasing in the presence of CFO.",
        "keywords": [
            "code-division multiple access cdma",
            "multicarrier mc",
            "carrier frequency offset cfo",
            "MultiCarrier (MC)",
            "Code-Division Multiple Access (CDMA)",
            "Carrier Frequency Offset (CFO)"
        ],
        "authors": [
            {
                "name": "Ying Huang",
                "org": "Beijing Jiaotong University School of Electronics and Information Engineering Beijing 100044 China Beijing 100044 China"
            },
            {
                "name": "Wei Yang",
                "org": "Beijing Jiaotong University School of Electronics and Information Engineering Beijing 100044 China Beijing 100044 China"
            },
            {
                "name": "Junying Liu",
                "org": "Beijing Jiaotong University School of Electronics and Information Engineering Beijing 100044 China Beijing 100044 China"
            }
        ],
        "venue": "Journal of Electronics (china)",
        "year": 2007
    },
    "o43Due1a": {
        "id": "o43Due1a",
        "title": "Performance Analysis of MC-CDMA System in a Multipath Fading Channel",
        "abstract": "In this paper, a reformed MC-CDMA scheme is proposed, which choose the symbol period transmitted multiple the chip period. This allows each subcarrier undergoes frequency selective fading channel and avoids the limitation on the chip rate and symbol rates of the former scheme, and furthermore it guarantees the multipath signals can be separated effectively. The Bit Error Rate (BER) expression is derived in a multipath fading channel, which is verified through simulations. Compared with the typical MC-CDMA scheme the BER performance of the proposed system is improved significantly because of the extra path gain.",
        "keywords": [
            "Bit Error Rate (BER)",
            "Multicarrier CDMA",
            "Multipath fading"
        ],
        "authors": [
            {
                "name": "Yang Wei",
                "org": ""
            },
            {
                "name": "Li Hang",
                "org": ""
            },
            {
                "name": "Zhenhui Tan",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            },
            {
                "name": "Shixin Cheng",
                "org": "Southeast University(Southeast University,Southeast Univ),Nanjing,China"
            }
        ],
        "venue": "Journal of Electronics & Information Technology",
        "year": 2007
    },
    "VDojdGfl": {
        "id": "VDojdGfl",
        "title": "DOA Estimation for MC-CDMA System with Antenna Array",
        "abstract": "In this paper,a Direction of Arrival(DOA) estimation algorithm is proposed for uplink MC-CDMA system with antenna array.By utilizing the orthogonality of spreading codes and frequency diversity of MC-CDMA,the users' signals are separated and enhanced,and the multiple access interference(MAI) is suppressed.After that the conventional subspace based on DOA estimation is applied to estimate the DOAs of users' signals.Simulation results show that the error of estimating users' DOA is small enough to effectively distinguish users' DOA respectively.",
        "keywords": [
            "antenna array",
            "direction of arrival estimation",
            "mc-cdma system",
            "direction of arrival",
            "code division multiple access"
        ],
        "authors": [
            {
                "name": "ZHANG De-zhen",
                "org": "School of Electronics and Information Engineering,Beijing Jiaotong University,Beijing ,China"
            },
            {
                "name": "YANG Wei",
                "org": "School of Electronics and Information Engineering,Beijing Jiaotong University,Beijing ,China"
            },
            {
                "name": "LI Ying",
                "org": "School of Electronics and Information Engineering,Beijing Jiaotong University,Beijing ,China"
            }
        ],
        "venue": "Journal of Beijing Jiaotong University",
        "year": 2007
    },
    "cUmBi9JX": {
        "id": "cUmBi9JX",
        "title": "Iteratative soft interference cancellation for uplink turbo-coded MIMO MC-CDMA system",
        "abstract": "A SISO iterative joint detection and decoding receiver structure is proposed in an uplink turbo-coded multiple-input multiple-output (MIMO) multicarrier code division multiple access (MC-CDMA) system. The SISO detector is achieved by using soft interference cancellation V-BLAST detection and multiuser detection with minimum mean square error (MMSE) technique. And the soft interference cancellation is composed of the canceling of multiple-access interference and co-antenna interference (CAI). Simulation results show that the iterative cancellation receiver in turbo coded system can gain much better performance than conventional receiver in uncoded system. A low-complexity scheme is also presented. © 2007 IEEE.",
        "keywords": [
            "interference cancellation",
            "mc-cdma",
            "mimo",
            "code division multiple access",
            "turbo code",
            "turbo codes",
            "minimum mean square error"
        ],
        "authors": [
            {
                "name": "Ximei Qiao",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            },
            {
                "name": "Wei Yang",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            },
            {
                "name": "Wenwen Liu",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            }
        ],
        "venue": "2007 International Conference on Wireless Communications, Networking and Mobile Computing, WiCOM 2007",
        "year": 2007
    },
    "BFc5Y1qC": {
        "id": "BFc5Y1qC",
        "title": "Node localization in wireless sensor networks for coal mine security monitoring",
        "abstract": "The localization algorithm based on the received signal strength index(RSSI) was proposed and optimized for wireless sensor networks of coal mine security monitoring,and consequently several factors which affect the localization precision was analyzed.Simulation results show that the optimized algorithm based on RSSI improves the localization precision effectively.For example,when the normal offsets of path loss are 4 and 6 respectively,the relative errors drop approximately from 0.21 and 0.35 to 0.18 and 0.29.",
        "keywords": [
            "received signal strength index(RSSI)",
            "wireless sensor networks",
            "node localization",
            "coal mine"
        ],
        "authors": [
            {
                "name": "YANG Wei",
                "org": "Key Laboratory of All Optical Network and Advanced Telecommunication Network,Ministry of Education,Beijing Jiaotong University,Beijing ,China;State Key Laboratory of Fire Science,University of Science and Technology of China,Hefei ,China"
            },
            {
                "name": "ZHOU Si-yong",
                "org": "Key Laboratory of All Optical Network and Advanced Telecommunication Network,Ministry of Education,Beijing Jiaotong University,Beijing ,China"
            },
            {
                "name": "QIAO Hua",
                "org": "High-Tech.Department,Tiandi Science & Technology Co.,Ltd.,Beijing ,China"
            }
        ],
        "venue": "Journal of China Coal Society",
        "year": 2007
    },
    "FyB6WJ41": {
        "id": "FyB6WJ41",
        "title": "Performance analysis of space-time block-coded multitone CDMA system",
        "abstract": "A space-time block-coded multitone code-division multiple-access(STBC MT-CDMA) system was proposed.The uplink bit error rate(BER) performance of the proposed system with maximum ratio combining(MRC) was theoretically analyzed in a multipath fading channel and the corresponding BER expressions were derived,which was verified through simulations.Numerical results show that the BER performance,error floor and capacity of the proposed system are improved significantly due to the joint space-time and path gain.",
        "keywords": [
            "Bit error rate",
            "Multipath fading",
            "Multitone CDMA",
            "Space-time block-code"
        ],
        "authors": [
            {
                "name": "YANG Wei",
                "org": "Modern Telecommunication Institute,Beijing Jiaotong University,Beijing ,China;National Mobile Communications Research Laboratory,Southeast University,Nanjing ,China"
            },
            {
                "name": "XinSheng Wang",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            }
        ],
        "venue": "Journal on Communications",
        "year": 2007
    },
    "gPdywsmG": {
        "id": "gPdywsmG",
        "title": "DOA estimation for MC-CDMA system with antenna array",
        "abstract": "In this paper, a Direction of Arrival (DOA) estimation algorithm is proposed for uplink MC-CDMA system with antenna array. By utilizing the orthogonality of spreading codes and frequency diversity of MC-CDMA, the users' signals are separated and enhanced, and the multiple access interference (MAI) is suppressed. After that the conventional subspace based on DOA estimation is applied to estimate the DOAs of users' signals. Simulation results show that the error of estimating users' DOA is small enough to effectively distinguish users' DOA respectively.",
        "keywords": [
            "Antenna array",
            "Direction of arrival estimation",
            "MC-CDMA system"
        ],
        "authors": [
            {
                "name": "Dezhen Zhang",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            },
            {
                "name": "Wei Yang",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            },
            {
                "name": "Ying Li",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            }
        ],
        "venue": "Beijing Jiaotong Daxue Xuebao/Journal of Beijing Jiaotong University",
        "year": 2007
    },
    "7YPnoIrv": {
        "id": "7YPnoIrv",
        "title": "Successive beamforming, multiuser detection and diversity reception for multicarrier DS-CDMA system with antenna array",
        "abstract": "Code-Division Multiple-Access (CDMA) systems are interference limited, and therefore efficient interference management is\n necessary to enhance the performance of a CDMA system. In this paper, a successive beamforming (spatial filtering), linear\n decorrelating MultiUser Detection (MUD, temporal filtering) and diversity reception structure for uplink multicarrier Direct\n Sequence CDMA (DS-CDMA) system with antenna array are proposed. By beamforming, the antenna array suppresses interference\n according to the distinct array signature. Subsequently, linear decorrelating MUD is applied to separate the signals of different\n users and eliminate Multiple Access Interference (MAI). Finally, the decorrelated signals at different subcarriers that belong\n to the same user are combined to achieve frequency diversity. Simulation results show that the proposed structure offers significant\n Bit Error Rate (BER) performance improvement by successively exploiting the space-time-frequency processing.",
        "keywords": [
            "Multicarrier Direct Sequence Code-Division Multiple-Access (DS-CDMA)",
            "diversity",
            "MultiUser Detection (MUD)",
            "Antenna array",
            "antenna array",
            "multiuser detection mud",
            "multicarrier direct sequence code-division multiple-access ds-cdma",
            "Diversity"
        ],
        "authors": [
            {
                "name": "Wei Yang",
                "org": "Beijing Jiaotong University School of Electronics and Information Engineering Beijing 100044 China"
            },
            {
                "name": "Junshi Chen",
                "org": "Beijing Jiaotong University School of Electronics and Information Engineering Beijing 100044 China"
            },
            {
                "name": "Zhenhui Tan",
                "org": "Beijing Jiaotong University School of Electronics and Information Engineering Beijing 100044 China"
            },
            {
                "name": "Shixin Cheng",
                "org": "Beijing Jiaotong University School of Electronics and Information Engineering Beijing 100044 China"
            }
        ],
        "venue": "Journal of Electronics (china)",
        "year": 2007
    },
    "kNJIVEEj": {
        "id": "kNJIVEEj",
        "title": "Performance Analysis of MC-DS-CDMA Uplink Based on V-BLAST Algorithm",
        "abstract": "In this paper,a new MIMO MC-DS-CDMA system structure applying V-BLAST algorithm is proposed and analyzed.The bit error rate expression of the proposed uplink system is derived on condition that the number of receiving antennas is greater than that of transmitting antennas,and the BER expression is verified by computer simulations.Numerical results show that the MIMO MC-DS- CDMA system based on V-BLAST algorithm can improve the system performance and capacity.",
        "keywords": [
            "Multicarrier direct sequence code division multiple access (MC-DS-CDMA)",
            "Multiple-input-multiple-output(MIMO)",
            "Vertical-bell labs layered space-time(V-BLAST)"
        ],
        "authors": [
            {
                "name": "ZHOU Si-yong",
                "org": "School of Electronics and Information Engineering,Beijing Jiaotong University,Beijing ,China"
            },
            {
                "name": "YANG Wei",
                "org": "School of Electronics and Information Engineering,Beijing Jiaotong University,Beijing ,China"
            }
        ],
        "venue": "Journal of Beijing Jiaotong University",
        "year": 2007
    },
    "0gjCQoGl": {
        "id": "0gjCQoGl",
        "title": "Joint V-BLAST and multiuser detection in uplink MIMO MC-CDMA systems",
        "abstract": "Applying MIMO technique in conventional MC-CDMA scheme to form MIMO MC-CDMA system will enhance the system performance of MC-CDMA. A joint V-BLAST (vertical-bell labs layered space-time) and multiuser detection algorithm for MIMO MC-CDMA system was proposed. Based on a modified iterative interference cancellation V-BLAST detection with minimum mean squared error (MMSE), two groups of detection data were obtained for each user, and then maximum-likelihood (ML) scheme was applied on the iterative output of all users to select the better group of data to optimize system performance. Simulation results show that the proposed algorithm improves the BER performance of the system significantly.",
        "keywords": [
            "MC-CDMA",
            "MIMO",
            "Multiuser detection",
            "Multiuser interference",
            "V-BLAST"
        ],
        "authors": [
            {
                "name": "Wenwen Liu",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            },
            {
                "name": "Wei Yang",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            }
        ],
        "venue": "Xitong Fangzhen Xuebao / Journal of System Simulation",
        "year": 2007
    },
    "FerkxZgF": {
        "id": "FerkxZgF",
        "title": "Joint V-BLAST and Multiuser Detection in Uplink MIMO MC-CDMA Systems",
        "abstract": "Applying MIMO technique in conventional MC-CDMA scheme to form MIMO MC-CDMA system will enhance the system performance of MC-CDMA. A joint V-BLAST(Vertical-Bell Labs Layered Space-Time)and multiuser detection algorithm for MIMO MC-CDMA system was proposed. Based on a modified iterative interference cancellation V-BLAST detection with minimum mean squared error(MMSE), two groups of detection data were obtained for each user, and then maximum-likelihood(ML)scheme was applied on the iterative output of all users to select the better group of data to optimize system performance. Simulation results show that the proposed algorithm improves the BER performance of the system significantly.",
        "keywords": [
            "multiuser interference",
            "MIMO",
            "V-BLAST",
            "MC-CDMA",
            "multiuser detection"
        ],
        "authors": [
            {
                "name": "YANG Wei",
                "org": " Modern Telecommunication Institute, Beijing Jiaotong University, Beijing , China; National Mobile Communications Research Laboratory, Southeast University, Nanjing , China"
            }
        ],
        "venue": "Journal of System Simulation",
        "year": 2007
    },
    "rlU1pbHv": {
        "id": "rlU1pbHv",
        "title": "Design practice on grid type coal mine monitoring and measurement network with wireless sensor",
        "abstract": "According to the large scale monitoring and measurement network with the wireless sensor for a part of mine roadway,the paper provided a grid type coal mine monitoring and measurement network with wireless sensors.The topology mechanism,route mechanism and conflict elimination mechanism of the network were designed.The wireless sensor node was developed.The auto monitoring and measurement operation mode of the wireless sensor network was designed.The simulation of the mine roadway environment for the system was tested with good test results.",
        "keywords": [
            "wireless sensor network",
            "monitoring and measuring",
            "mine safety",
            "grid type structure"
        ],
        "authors": [
            {
                "name": "LIU Bin",
                "org": "Key Lab of Full Optical Net and Modern Communication Net of Ministry of Education,Beijing Jiaotong University,Beijing ,China;State Key Lab of Fire Science,University of Science and Technology of China,Hefei ,China"
            },
            {
                "name": "YANG Wei",
                "org": "Key Lab of Full Optical Net and Modern Communication Net of Ministry of Education,Beijing Jiaotong University,Beijing ,China;State Key Lab of Fire Science,University of Science and Technology of China,Hefei ,China"
            }
        ],
        "venue": "Coal Science and Technology",
        "year": 2007
    },
    "q6MOPj8N": {
        "id": "q6MOPj8N",
        "title": "Scheduling Design for Hierarchical Wireless Sensor Network for Periodically Monitoring Gas in Coal Mine",
        "abstract": "In order to ensure the reliable operation and realization of periodical inspection function of hierarchical wireless sensor network used in coal mines for monitoring gas,we designed the operation sequence of the network.Based on the characteristics of the hierarchical structure,a data collecting scheduling for the infrastructural network and a data transmitting scheduling for the upper backbone network were proposed respectively.Aiming at the problem that the data collection in lower basic network is quite possible to fail,we proposed an overtime handling mechanism of data collection for the infrastructural network.According to the possibility of data transmitting failure,we put forward an overtime handling mechanism of data transmitting for the upper backbone network.Experiments in both laboratory and underground coal mine indicate that the hierarchical wireless sensor network is reliable in operation and capable of realizing the periodical inspection function.",
        "keywords": [
            "scheduling",
            "gas",
            "periodical inspection",
            "wireless sensor network"
        ],
        "authors": [
            {
                "name": "NIU Chun-lei",
                "org": "State Key Laboratory of Rail Traffic Control and Safety,Beijing Jiaotong University,Beijing ,China;State Key Laboratory of Coal Resources and Mine Safety,China University of Mining & Technology,Beijing ,China"
            },
            {
                "name": "YANG Wei",
                "org": "State Key Laboratory of Rail Traffic Control and Safety,Beijing Jiaotong University,Beijing ,China;State Key Laboratory of Coal Resources and Mine Safety,China University of Mining & Technology,Beijing ,China"
            },
            {
                "name": "WANG Bin",
                "org": "State Key Laboratory of Rail Traffic Control and Safety,Beijing Jiaotong University,Beijing ,China;State Key Laboratory of Coal Resources and Mine Safety,China University of Mining & Technology,Beijing ,China"
            }
        ],
        "venue": "Journal of Mining & Safety Engineering",
        "year": 2008
    },
    "bjz7e4J7": {
        "id": "bjz7e4J7",
        "title": "Statistical channel model of wideband UHF radio waves along rectangular-like mine tunnel",
        "abstract": "From the point of view of statistical model establishment of wireless channel, the large-scale path loss and small-scale statistical characteristics of multipath signals of the wideband UHF radio waves along rectangular-like mine tunnel were analyzed. Based on the Nakagami distribution a multi-section statistical channel model of the wideband UHF radio waves along rectangular-like mine tunnel was proposed. By utilizing the established model, the statistical characteristics of the wideband wireless channel of mine tunnel at 900, 1800, 2400 MHz were simulated and investigated. Simulation results show that the large-scale path loss is enlarged with the carrier frequency increasing when the transmission distance is the same. Compared with that along empty-straight tunnel the large-scale path loss is enlarged seriously along curve or embranchment tunnel. According to the different relationship of position between transmitter and receiver in mine tunnel as well as carrier frequency, the small-scale time delay may show different variable characteristics.",
        "keywords": [
            "Channel",
            "Large-scale",
            "Mine tunnel",
            "Nakagami distribution",
            "Small-scale"
        ],
        "authors": [
            {
                "name": "Wei Yang",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            },
            {
                "name": "Ying Li",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            },
            {
                "name": "SUN Ji-ping",
                "org": "China University of Mining Technology(China University of Mining and Technology,China Univ. of Mining and Technol.),Beijing,China"
            }
        ],
        "venue": "Meitan Xuebao/Journal of the China Coal Society",
        "year": 2008
    },
    "2ZjlQK8s": {
        "id": "2ZjlQK8s",
        "title": "Performance comparison of multi-carrier CDMA systems with antenna array",
        "abstract": "The performance of the three typical multi-carrier CDMA systems can be improved significantly by applying antenna array. The transmitted signals, received signals and channel models of the multi-carrier CDMA systems with antenna array are discussed, and the bit error rate (BER) formulas of the three systems are provided. The parameters are analyzed and the BER performances are compared for the three systems under the condition of the same spectral efficiency. Numerical results indicate that the antenna array MC-CDMA performs best for the joint space and frequency diversity gain; antenna array MT-CDMA takes the second place for the joint space and time diversity gain; and antenna array MC-DS-CDMA performs the worst among the three systems since only the space gain can be obtained for this scheme.",
        "keywords": [
            "Antenna array",
            "Frequency efficiency",
            "Multi-carrier CDMA"
        ],
        "authors": [
            {
                "name": "Ximei Qiao",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            },
            {
                "name": "Wei Yang",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            }
        ],
        "venue": "Beijing Jiaotong Daxue Xuebao/Journal of Beijing Jiaotong University",
        "year": 2008
    },
    "1n4CFL8H": {
        "id": "1n4CFL8H",
        "title": "Research on mine underground positioning technology based on wireless local area network",
        "abstract": "The wireless positioning of the personnel and locomotives in the underground mine will have a great significance to improve the mine production efficiency and enhance the mine safety production level. Under the framework of the wireless local area network(WLAN), receiving the received signal strength indictor (RSSI) based on access point (AP), the mine underground wireless positioning was conducted in combination with the experiences and the estimation. The experiments showed that the method could have the positioning accuracy within 9 meter, which could fully meet the wireless positioning requirements in underground mine. The method also had overcome the shortage of radio frequency identification (RFID) technology which only could perform the function of identifying and recording applied currently in underground mines.",
        "keywords": [
            "wireless positioning",
            "WLAN",
            "mine underground",
            "received signal strength indictor"
        ],
        "authors": [
            {
                "name": "TIAN Hong-xian",
                "org": " State Key Lab of Railway Transportation Control and Safety, Beijing Jiaotong University, Beijing , China"
            },
            {
                "name": "YANG Wei",
                "org": " State Key Lab of Railway Transportation Control and Safety, Beijing Jiaotong University, Beijing , China; State Key Lab of Coal Resources and Safety Mining, China University of Mining and Technology%%#Beijing%%#, Beijing , China"
            }
        ],
        "venue": "Coal Science and Technology",
        "year": 2008
    },
    "0MKxxOt3": {
        "id": "0MKxxOt3",
        "title": "Analysis and Comparison of the Performance About Wireless Modulation Technologies in Empty and Straight Mine Tunnel",
        "abstract": "In order to establish an effective wireless communication system in underground coal mine.After studying the fading situation of mine tunnel,this paper found out the relationship between the bit error rate(BER) of narrowband and wideband signal and transmission distance in the empty and straight mine laneway.The effects of the laneway channel on the signal at the frequency of 900 MHz、1800 MHz and 2.4 GHz is studied respectively.By comparison and analysis,it is concluded that compared with the signal at the frequency of 900 MHz and 1800 MHz,the signal of 2.4 GHz cover longer distance in the laneway when the data rate is low(such as several tens of kbit/s).Besides,wideband signal can improve the BER performance significantly,transmit more several decameters,and is more suitable for wireless communication than narrowband signal in mine tunnel.",
        "keywords": [
            "Rician",
            "waveguide propagation model",
            "empty and straight mine laneway"
        ],
        "authors": [
            {
                "name": "NIU Li",
                "org": "State Key Laboratory of Rail Traffic Control and Safety,Beijing Jiaotong University,Beijing ,China;State Key Laboratory of Coal Resources and Safe Mining,China University of Mining and Technology,Beijing ,China"
            },
            {
                "name": "YANG Wei",
                "org": "State Key Laboratory of Rail Traffic Control and Safety,Beijing Jiaotong University,Beijing ,China;State Key Laboratory of Coal Resources and Safe Mining,China University of Mining and Technology,Beijing ,China"
            }
        ],
        "venue": "Journal of Beijing Jiaotong University",
        "year": 2008
    },
    "WG8Oa1Al": {
        "id": "WG8Oa1Al",
        "title": "Analysis of simulation performance in TH-UWB communication system by using convolution codes to against the ISI",
        "abstract": "In this paper, our work is focused on the ISI (inter symbol interference) that is caused by multipath effects in UWB based wireless sensor network, and we present the BER simulation of the TH-PPM-UWB (convolution coded and uncoded schemes) communication system that has ISI or not in two different channels, there are eight cases, and the results indicate that the coded scheme performs well to against ISI than that of the uncoded scheme, and the more serious the ISI become, the more efficient the coded TH-PPM-UWB.",
        "keywords": [
            "Channel model",
            "Convolution codes",
            "Inter symbol interference (ISI)",
            "Time hopping pulse position modulation (TH-PPM)",
            "Ultra-wideband (UWB)"
        ],
        "authors": [
            {
                "name": "Lingtong Kong",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            },
            {
                "name": "Huaiyi Jia",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            },
            {
                "name": "Wei Yang",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            }
        ],
        "venue": "Beijing Jiaotong Daxue Xuebao/Journal of Beijing Jiaotong University",
        "year": 2008
    },
    "ZkGqQ1lV": {
        "id": "ZkGqQ1lV",
        "title": "Analysis on communication performances of DS-CDMA modulation technology in mine roadway",
        "abstract": "In order to provide an effective radio modulation technology suitable to the signal channel features of the mine roadway and according to the time delay of the wideband radio wave along mine roadway as well as the wideband statistic sectional signal model of the mine roadway established base on Nakagami distribution, the paper analyzed the wideband radio communication performances of the direct sequence code-division multi access input modulation in the mine roadway under the typical UHF frequency of 1.8 GHz and 2.4 GHz. The DS-CDMA communication system can improve its system performances with the effective application of the multipath signals. In a similar mine roadway condition, the 2.4 GHz system could make more multipath separated signals than the 1.8 GHz system and the BER performances could be better than the 1.8 GHz system. The Doppler frequency offset and impulse interference would have a serious affect to the BER performances of DS-CDMA communication system in the mine roadway. When Doppler frequency offset and impulse interference are high, the BER performance of the DS-CDMA system in the mine roadway would be severely decreased. In this case, the BER performance of the 2.4 GHz system in the mine roadway would be poor than the 1.8 GHz system.",
        "keywords": [
            "Nakagami distribution",
            "mine roadway",
            "bit error rate (BER)",
            "DS-CDMA modulation"
        ],
        "authors": [
            {
                "name": "YANG Wei",
                "org": " State Key Lab of Railway Traffic Control and Safety, Beijing Jiaotong University, Beijing , China; State Key Lab of Coal Resources and Safety Mining,China University of Mining and Technology%%#Beijing%%#, Beijing , China"
            },
            {
                "name": "NIU Li",
                "org": " State Key Lab of Railway Traffic Control and Safety, Beijing Jiaotong University, Beijing , China"
            },
            {
                "name": "QI Hui",
                "org": " State Key Lab of Coal Resources and Safety Mining,China University of Mining and Technology%%#Beijing%%#, Beijing , China"
            }
        ],
        "venue": "Coal Science and Technology",
        "year": 2008
    },
    "2F3IPLu1": {
        "id": "2F3IPLu1",
        "title": "Performance Comparison of Multi-Carrier CDMA Systems with Antenna Array",
        "abstract": "The performance of the three typical multi-carrier CDMA systems can be improved significantly by applying antenna array.The transmitted signals,received signals and channel models of the multi-carrier CDMA systems with antenna array are discussed,and the bit error rate(BER)formulas of the three systems are provided.The parameters are analyzed and the BER performances are compared for the three systems under the condition of the same spectral efficiency.Numerical results indicate that the antenna array MC-CDMA performs best for the joint space and frequency diversity gain;antenna array MT-CDMA takes the second place for the joint space and time diversity gain;and antenna array MC-DS-CDMA performs the worst among the three systems since only the space gain can be obtained for this scheme.",
        "keywords": [
            "multi-carrier CDMA",
            "frequency efficiency",
            "antenna array"
        ],
        "authors": [
            {
                "name": "QIAO Ximei",
                "org": "State Key Laboratory of Rail Traffic Control and Safety,Beijing Jiaotong University,Beijing ,China;National Mobile Communications Research Laboratory,Southeast University,Nanjing Jiangsu ,China"
            },
            {
                "name": "YANG Wei",
                "org": "State Key Laboratory of Rail Traffic Control and Safety,Beijing Jiaotong University,Beijing ,China;National Mobile Communications Research Laboratory,Southeast University,Nanjing Jiangsu ,China"
            }
        ],
        "venue": "Journal of Beijing Jiaotong University",
        "year": 2008
    },
    "T7k72dPC": {
        "id": "T7k72dPC",
        "title": "Realization of hiberarchy wireless sensor network for mine laneway monitoring",
        "abstract": "According to the requirement of monitoring the environment of coal mine laneway and the characteristics of the laneway landform,a kind of hiberarchy wireless sensor network was proposed for laneway monitoring.The topology control mechanism and routing mechanism were designed,correspondingly hardware of the sensor node and the protocol stack were developed,and two work modes for the system were designed.Simulation experiment in the laboratory proves operated well,the data exceeding the threshold could be delivered timely in interrupt mode and data could be periodically gathered steadily and reliably in periodic monitor mode.",
        "keywords": [
            "Mine laneway",
            "Sensor network",
            "Wireless monitoring"
        ],
        "authors": [
            {
                "name": "YANG Wei",
                "org": "Key Laboratory of All Optical Network and Advanced Telecommunication Network,Ministry of Education,Beijing Jiaotong University,Beijing ,China;State Key Laboratory of Coal Resources and Safe Mining,China University of Mining and Technology%%#Beijing%%#,Beijing ,China"
            },
            {
                "name": "WANG Bin",
                "org": "Key Laboratory of All Optical Network and Advanced Telecommunication Network,Ministry of Education,Beijing Jiaotong University,Beijing ,China;State Key Laboratory of Coal Resources and Safe Mining,China University of Mining and Technology%%#Beijing%%#,Beijing ,China"
            }
        ],
        "venue": "Journal of China Coal Society",
        "year": 2008
    },
    "Aqi5LfZO": {
        "id": "Aqi5LfZO",
        "title": "Performance analysis of MT-CDMA modulation in the mine tunnel",
        "abstract": "The bit error rate (BER) performance of multitone code-division-multiple-access (MT-CDMA) modulation in the mine tunnel was analyzed based on an established multi-section Nakagami distribution statistical channel model for wideband radio wave. In the straight or embranchment mine tunnel, the effects of attenuation of multipath signals, Doppler frequency offset and impulse interference on the BER performance of MT-CDMA at 1.8 GHz and 2.4 GHz were studied. The results show that the MT-CDMA in the mine tunnel can effectively utilize the multipath signals to improve the BER performance of the system. For the same attenuation coefficient, the more the number of multipath signals are, the better the BER performance of the system is. The BER performance of MT-CDMA in the mine tunnel at 2.4 GHz is better than that at 1.8 GHz. When the attenuation of multipath signals, Doppler frequency offset, or impulse interference is larger, the MT-CDMA in the mine tunnel may not communicate reliably, especially in the embranchment mine tunnel.",
        "keywords": [
            "Bit error rate",
            "Mine tunnel",
            "MT-CDMA modulation",
            "Nakagami distribution"
        ],
        "authors": [
            {
                "name": "Wei Yang",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            },
            {
                "name": "Li Niu",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            }
        ],
        "venue": "Zhongguo Kuangye Daxue Xuebao/Journal of China University of Mining and Technology",
        "year": 2009
    },
    "JtUCh0ey": {
        "id": "JtUCh0ey",
        "title": "Research on Synchronous Technology of Mesh Grid Type Coal Mine Monitoring and Measuring Radio Sensor Network",
        "abstract": "In order to ensure the effective transmission of the monitoring and measuring data in the radio sensor network in the mesh grid type underground mine,according to the periodical\"active or sleeping\"of the network,in combined with the utilization strategy of the time interval distributed radio channel,the related suitable synchronous method was provided.The method with the distributed broadcast mode and the synchronous point changing mechanism,with the multi transferred router synchronous broadcast fame,could make the all points in the network received the broadcast frames.Therefore the work status of the points could be adjusted and the synchronization of all points in the network could be ensured.The test results showed that the method could reduce the channel application conflict occurred in the transmission of the monitoring and measuring data and could rapidly recover communication between the point and network,which could improve the reliability of the information transmission.",
        "keywords": [
            "synchronous point conversion",
            "broadcast",
            "radio sensor network",
            "synchronous"
        ],
        "authors": [
            {
                "name": "ZHANG De-zhen",
                "org": "State Key Lab of Railway Traffic Control and Safety,Beijing Jiaotong University,Beijing ,China;State Key Lab of Coal Resources and Safety Mining,China University of Mining and Technology %%#Beijing%%#,Beijing ,China;Henan Key Laboratory of Coal Mine Methane and Fire Prevention,Henan Polytechnic University,Jiaozuo ,China"
            },
            {
                "name": "YANG Wei",
                "org": "State Key Lab of Railway Traffic Control and Safety,Beijing Jiaotong University,Beijing ,China;State Key Lab of Coal Resources and Safety Mining,China University of Mining and Technology %%#Beijing%%#,Beijing ,China;Henan Key Laboratory of Coal Mine Methane and Fire Prevention,Henan Polytechnic University,Jiaozuo ,China"
            },
            {
                "name": "LIU Bin",
                "org": "State Key Lab of Railway Traffic Control and Safety,Beijing Jiaotong University,Beijing ,China"
            }
        ],
        "venue": "Coal Science and Technology",
        "year": 2009
    },
    "GoqLfCEP": {
        "id": "GoqLfCEP",
        "title": "Simulation Analysis of OFDM Modulation in Mine Tunnels",
        "abstract": "Based on the multi-section Nakagami distribution statistical channel model of mine tunnel for wideband radio wave,the bit error rate(BER) performance of Orthogonal Frequency Division Multiplexing(OFDM) modulation at 2.4 GHz and 5.8 GHz in mine tunnel was investigated.According to the different root-mean-square(RMS) time delay of wideband radio wave along empty-straight or embranchment mine tunnel,the main parameters of OFDM modulation at 2.4 GHz and 5.8 GHz are designed.At the same signal-noise-radio(SNR),original data rate and wireless channel,the BER performance of OFDM at 5.8 GHz is better than that at 2.4 GHz for both empty-straight and embranchment mine tunnel.The OFDM modulation in mine tunnel shows good ability to resist impulse interference at both 2.4 GHz and 5.8 GHz.Doppler frequency offset has serious effect on the BER performance of OFDM modulation in mine tunnel.It affects the BER performance at 5.8 GHz more severe than that at 2.4 GHz.In the case of Doppler frequency offset,when the SNR is larger than 20 dB,the continuous increase of SNR can not improve the BER performance of the system significantly.",
        "keywords": [
            "wireless communication",
            "bit error rate(BER)",
            "mine tunnel",
            "nakagami distribution",
            "orthogonal frequency division multiplexing(OFDM)"
        ],
        "authors": [
            {
                "name": "LI Ying",
                "org": "State Key Laboratory of Rail Traffic Control and Safety,Beijing Jiaotong University,Beijing ,China;State Key Laboratory of Coal Resources and Safe Mining(China University of Mining and Technology"
            },
            {
                "name": "YANG Wei",
                "org": "State Key Laboratory of Rail Traffic Control and Safety,Beijing Jiaotong University,Beijing ,China;State Key Laboratory of Coal Resources and Safe Mining(China University of Mining and Technology"
            }
        ],
        "venue": "Journal of Beijing Jiaotong University",
        "year": 2009
    },
    "zjcYc4KY": {
        "id": "zjcYc4KY",
        "title": "Research on an optimal QoS DBA implement mechanism of EPON multicast",
        "abstract": "By referring to economic mode, a QoS priority algorithm for EPON multicast was introduced based on its network attribute, user attribute and market attribute. Based on the multicast QoS priority, the network bandwidth was dynamically allocated among multicast services. It could overcome the disadvantages of lower benefit and higher loss rate of package in the network-priority-based QoS mechanism. It effectively reduced delay jitter of package by reshaping the variable-length and disorderly Ethernet downstream frame into the constant-length and orderly one. The simulation result verifies its merits well.",
        "keywords": [
            "Dynamic bandwidth allocation",
            "Ethernet passive optical network",
            "Multicast",
            "Quality of service"
        ],
        "authors": [
            {
                "name": "ZHANG Jin-yu",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            },
            {
                "name": "Wei Yang",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            },
            {
                "name": "Li Liu",
                "org": "New Jersey Institute of Technology(New Jersey Institute of Technology,New Jersey Inst of Technology),Newark,United States"
            }
        ],
        "venue": "Tongxin Xuebao/Journal on Communications",
        "year": 2009
    },
    "3Xx1MhTf": {
        "id": "3Xx1MhTf",
        "title": "Design and implementation of wireless video surveillance system in underground coal mine",
        "abstract": "Setting up wireless video surveillance systems in underground coal mine will offset the shortcomings of the traditional wired monitoring system,and it enhance the video surveillance ability in underground coal mine.It is an important measure to guarantee the safety further or deal with an emergency in underground coal mine.A kind of wireless video surveillance system was designed based on digital mine integrated wireless local access network.The key technologies involved were developed and debugged,and the wireless video surveillance system was tested in underground coal mine.7figs.,8refs.",
        "keywords": [
            "underground coal mine",
            "wireless video surveillance",
            "wireless network camera",
            "wireless local access network(WLAN)"
        ],
        "authors": [
            {
                "name": "LIU Yan-bing",
                "org": "Key Laboratory of All Optical Network and Advanced Telecommunication Network,Ministry of Education,Beijing Jiaotong University,Beijing,China;Henan Key Laboratory of Coal Mine Methane and Fire Prevention,Henan Polytechnic University,Jiaozuo ,China"
            },
            {
                "name": "YANG Wei",
                "org": "Key Laboratory of All Optical Network and Advanced Telecommunication Network,Ministry of Education,Beijing Jiaotong University,Beijing,China;State Key Laboratory of Coal Resources and Safe Mining,China University of Mining and Technology,Beijing ,China"
            },
            {
                "name": "WANG Shu-guang",
                "org": "Key Laboratory of All Optical Network and Advanced Telecommunication Network,Ministry of Education,Beijing Jiaotong University,Beijing,China"
            },
            {
                "name": "LI Lin-tao",
                "org": "Key Laboratory of All Optical Network and Advanced Telecommunication Network,Ministry of Education,Beijing Jiaotong University,Beijing,China"
            }
        ],
        "venue": "Journal of Hunan University of Science & Technology(Natural Science Edition)",
        "year": 2009
    },
    "8lKHBApx": {
        "id": "8lKHBApx",
        "title": "Simulation Analysis of MC-DS-CDMA Modulation in Mine Tunnel",
        "abstract": "Based on the multi-section Nakagami distribution statistical channel model of mine tunnel for wideband radio wave, the bit error rate (BER) performance of multicarrier direct-sequence code-division-multiple-access (MC-DS-CDMA) modulation in mine tunnel was simulated. Simulation results indicate that the BER performance of MC-DS-CDMA is decided mainly by the channel attenuation, and not by the root-mean-square (RMS) time delay of wideband radio wave along straight or embranchment tunnel. Doppler frequency offset has serious effect on the BER performance of MC-DS-CDMA modulation in mine tunnel. The BER performance of MC-DS-CDMA modulation in mine tunnel is affected little by impulse interference when it happens infrequently. However, the BER performance is affected seriously by impulse interference when it happens frequently. In case of multiusers, the BER performance of MC-DS-CDMA in mine tunnel is much better compared to that of DS-CDMA modulation.",
        "keywords": [
            "Nakagami distribution",
            "MC-DS-CDMA modulation",
            "bit error rate (BER)",
            "mine tunnel"
        ],
        "authors": [
            {
                "name": "YANG Wei",
                "org": " State Key Laboratory of Rail Traffic Control and Safety, Beijing Jiaotong University, Beijing , China; State Key Laboratory of Coal Resources and Safe Mining, China University of Mining and Technology, Beijing , China"
            },
            {
                "name": "NIU Li",
                "org": " State Key Laboratory of Rail Traffic Control and Safety, Beijing Jiaotong University, Beijing , China"
            }
        ],
        "venue": "Journal of System Simulation",
        "year": 2009
    },
    "ePEvI9sh": {
        "id": "ePEvI9sh",
        "title": "Research on the optimal spare part inventory control method for telecom network",
        "abstract": "An optimal economic replacing algorithm is introduced, it can avoid disadvantages of emphasizing particularly on performance criticality but neglecting cost occurred in the replacing algorithms based on the age and the performance degradation degree. An optimal performance inventory control algorithm is put forward, it can overcome the demerits of ignoring the technical depreciation and capital overstocking processed by the inventory control algorithm based on the minimal total expense. Simulations show that they can largely reduce the total cost and the capital overstocking.",
        "keywords": [
            "Inventory control method component",
            "Optimal",
            "Spare part"
        ],
        "authors": [
            {
                "name": "ZHANG Jin-yu",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            },
            {
                "name": "Wei Yang",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            }
        ],
        "venue": "Beijing Youdian Daxue Xuebao/Journal of Beijing University of Posts and Telecommunications",
        "year": 2009
    },
    "npUZQR4I": {
        "id": "npUZQR4I",
        "title": "Study on the adaptation modulation of underground mine multimedia wireless sensor network",
        "abstract": "Aiming at a simple multimedia monitoring scene in the underground coal mine,the adaptation modulation for multi-band orthogonal-frequency-division-multiplexing ultra-wideband(MB-OFDM-UWB) based underground multimedia wireless sensor network was studied,in order to optimize the maximum throughput of the system for a given bit error rate(BER).IEEE 802.15.3a was chosen as the channel model for MB-OFDM-UWB signals transmitted along mine tunnel.Firstly,the fixed threshold for multiple-quadrature-amplitude-modulation(MQAM) adaptive modulation was obtained from the simulation figures.Then,the adaptive modulation for grouped-subcarrier algorithms was simulated and analyzed where four types of signal-to-noise calculation method for grouped-subcarrier algorithms were adopted.Simulation results show that it is an efficient way to improve the system performance by applying adaptive modulation to MB-OFDM-UWB based underground multimedia wireless sensor network.",
        "keywords": [
            "multimedia wireless sensor network",
            "adaptive modulation",
            "multi-band orthogonal-frequency-division-multiplexing ultra-wideband(MB-OFDM-UWB)"
        ],
        "authors": [
            {
                "name": "FAN Xin-yue",
                "org": "State Key Laboratory of Rail Traffic Control and Safety,Beijing Jiaotong University,Beijing ,China;Henan Key Laboratory of Coal Mine Methane and Fire Prevention,Henan Polytechnic University,Jiaozuo ,China"
            },
            {
                "name": "YANG Wei",
                "org": "State Key Laboratory of Rail Traffic Control and Safety,Beijing Jiaotong University,Beijing ,China;Henan Key Laboratory of Coal Mine Methane and Fire Prevention,Henan Polytechnic University,Jiaozuo ,China"
            }
        ],
        "venue": "Journal of China Coal Society",
        "year": 2009
    },
    "hzWDA2hs": {
        "id": "hzWDA2hs",
        "title": "Study on dynamic subcarrier allocation for underground mine multimedia wireless sensor network",
        "abstract": "A dynamic subcarrier allocation algorithms based on grouped ″Ratio-based Selection″ (RBS) is proposed. Operation complexity is reduced by the step of grouping, and power consume is decreased by the step of initializing subcarrier allocation and optimizing subcarrier allocation. At initial allocation phases, some adjacent subcarriers are allocated as a group. Then, the RBS dynamic subcarrier allocation is applied within a group, and the complexity is reduced by lowering the number of circulation times. At optimal allocation phases, initial allocation results are adjusted by exchanging subcarrier groups with bad performance which lower power consume further. Simulation results show that lower operation complexity and power consume are achieved with the propose algorithm at the price of little BER loss compared with the typical RBS algorithm.",
        "keywords": [
            "Dynamic subcarrier allocation",
            "Multi-band orthogonal-frequency-division-multiplexing ultra-wideband (MB-OFDM-UWB)",
            "Multimedia wireless sensor network"
        ],
        "authors": [
            {
                "name": "Xinyue Y. Fan",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            },
            {
                "name": "Wei Yang",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            }
        ],
        "venue": "Beijing Jiaotong Daxue Xuebao/Journal of Beijing Jiaotong University",
        "year": 2009
    },
    "xcGg0dKo": {
        "id": "xcGg0dKo",
        "title": "Topology Control Mechanism of Gradation Wireless Sensor Network for Gas Monitoring and Control",
        "abstract": "In order to improve the coal mine gas monitoring and measuring capacity,the paper provided and realized the topology mechanism of the gradation wireless sensor network based on the ZigBee protocol.The establishment procedure of the gradation network topological structure should include the establishment of the upper layer backbone network and the establishment of the low layer basic network.Whereas the establishment of the upper layer backbone network would also include the two procedures of the coordinator network establishment and the cluster head endpoint joining network.The ID distribution strategy of the network node was designed.The distribution procedure should include the cluster head endpoint distributed ID provided by the coordinator and the endpoint distributed ID provided by the cluster head endpoint.According to the variation problems of the network topological structure occurred during the network operation procedure,such as the terminal separated from or entered into the network,the relevant handling mechanism was designed.The lab and the coal mine site test results showed that the topologiy control mechanism provided could successfully generate the network and could have the relevant handling of the some topology structure variation occurred.",
        "keywords": [
            "wireless sensor network",
            "topology",
            "ID distribution",
            "coal mine"
        ],
        "authors": [
            {
                "name": "NIU Chun-lei",
                "org": "Ministry of Education's Key Lab of Full Optical Fiber Network and Modern Telecommunication Network,Beijing Jiaotong University,Beijing ,China;Henan Provincial Key Lab of Coal Mine Gas and Fire Disaster Prevention and Control,Henan Polytechnic University,Jiaozuo ,China;State Key Laboratory of Coal Resources and Safety Mining,China University of Mining and Technology%%#Beijing%%#,Beijing ,China"
            },
            {
                "name": "YANG Wei",
                "org": "Ministry of Education's Key Lab of Full Optical Fiber Network and Modern Telecommunication Network,Beijing Jiaotong University,Beijing ,China;Henan Provincial Key Lab of Coal Mine Gas and Fire Disaster Prevention and Control,Henan Polytechnic University,Jiaozuo ,China;State Key Laboratory of Coal Resources and Safety Mining,China University of Mining and Technology%%#Beijing%%#,Beijing ,China"
            }
        ],
        "venue": "Coal Science and Technology",
        "year": 2009
    },
    "duXV1D7Q": {
        "id": "duXV1D7Q",
        "title": "A power amplifier linearization method for TETRA multi-carrier system",
        "abstract": "A synergic crest factor reduction and digital predistortion scheme is proposed to solve the problem of the high requirement of power amplifier linearity in TETRA multi-carrier system.Peak windowing of crest factor reduction can reduce multi-carrier signal's peak average ratio and satisfy the requirement of modulation accuracy and out-of-band emissions,power amplifier's work point is increased consequently.Power amplifier appears memory nonlinearity in wideband multi-carrier system,a memory look-up-table predistortor is proposed for TETRA multi-carrier system,the proposed scheme can extend the linear range of power amplifier efficiently.The peak windowing and the memory predistortor are joined in TETRA multi-carrier system.The simulation result shows the extension of power amplifier linearity range,work point is increased 1.5dB simultaneously.Therefore the power amplifier's efficiency is improved.",
        "keywords": [
            "predistorter",
            "crest factor reduction",
            "peak average ratio",
            "power amplifier linearization"
        ],
        "authors": [
            {
                "name": "Zhang Qin",
                "org": "School of Electronics and Information Engineering,Beijing Jiaotong University,Beijing "
            },
            {
                "name": "Sun Xin",
                "org": "School of Electronics and Information Engineering,Beijing Jiaotong University,Beijing "
            },
            {
                "name": "Yang Wei",
                "org": "School of Electronics and Information Engineering,Beijing Jiaotong University,Beijing "
            }
        ],
        "venue": "Journal of Electronic Measurement and Instrument",
        "year": 2009
    },
    "nN4cmI0i": {
        "id": "nN4cmI0i",
        "title": "Iterative bidirectional decision feedback equalizer",
        "abstract": "In this paper, we propose a novel iterative approach to bidirectional decision feedback equalization (Bi-DFE). Bi-DFE performs two equalizations, one on the received signal and another on its time-reversed version. The arbitration for the forward and reverse DFEs is decided by minimum path metric in bidirectional Viterbi decoder. In order to further improve the performance of the Bi-DFE, iterative process can also be explored. The results of simulation and analysis show that the performance of the proposed iterative Bi-DFE is better than that of conventional DFE receiver such as normal mode DFE, time-reversal mode DFE, linear-combining bidirectional DFE (LC-BiDFE).",
        "keywords": [
            "bidirectional dfe",
            "iterative",
            "linear combining bidirectional dfe",
            "viterbi decoding",
            "iterative bidirectional decision feedback equalizer",
            "minimum path metric",
            "bidirectional viterbi decoder",
            "path metric",
            "time reversal mode dfe",
            "normal mode dfe",
            "decision feedback equalisers",
            "decoding",
            "viterbi algorithm",
            "time reversal",
            "viterbi decoder",
            "normal modes"
        ],
        "authors": [
            {
                "name": "Junhui Zhao",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            },
            {
                "name": "Wei Yang",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            },
            {
                "name": "Dongming Wang",
                "org": "Southeast University(Southeast University,Southeast Univ),Nanjing,China"
            }
        ],
        "venue": "Beijing",
        "year": 2009
    },
    "RIaGWFSE": {
        "id": "RIaGWFSE",
        "title": "FPGA implementation of V-BLAST detection algorithm in MIMO system",
        "abstract": "This paper presents FPGA implementation of various V-BLAST detection algorithms which are maximum likelihood, zero forcing and minimum mean squared error. Firstly, the MIMO V-BLAST system structure, the mathematical models and a variety of receiver detection algorithms have been studied detailedly. And then we analyze the characteristic and performance of typical algorithms and focus on using the Verilog hardware description language to implement the V-BLAST system architecture and the three detection algorithms on the Xilinx's Vertex Series FPGA, which can give good performance. Ultimately, these simulation results had been compared with each other in terms of complexity and error performance.",
        "keywords": [
            "ml",
            "verilog hardware description language",
            "zero forcing",
            "maximum likelihood estimation",
            "mmse",
            "zf",
            "hardware description languages",
            "fpga",
            "minimum mean squared error",
            "mimo system",
            "antenna arrays",
            "least mean squares methods",
            "v-blast",
            "telecommunication computing",
            "mimo communication",
            "receiver detection algorithms",
            "maximum likelihood",
            "v-blast detection algorithm",
            "xilinx vertex series fpga",
            "field programmable gate arrays",
            "mimo",
            "minimum mean square error",
            "system architecture",
            "binary phase shift keying",
            "mathematical model",
            "hardware description language"
        ],
        "authors": [
            {
                "name": "Le Sun",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            },
            {
                "name": "Wei Yang",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            },
            {
                "name": "Hu Huang",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            }
        ],
        "venue": "Beijing",
        "year": 2009
    },
    "LBa18ae4": {
        "id": "LBa18ae4",
        "title": "Multi-parameters monitoring underground coal mine environment using mesh-structured wireless sensor networks",
        "abstract": "In order to overcome the shortcomings of wireless sensor networks for single parameter monitoring in coal mines, a multi-parameters monitoring system for coal mine environment based on mesh structured wireless sensor network is proposed. Multi-kinds of sensors in a wireless node were adopted in the system, such that the integrated monitoring for coal mine environment parameters was achieved. By this way, the premonition information of accident can be caught and analyzed in time, so that coal mine accidents can be avoided significantly. The mode of multi-parameters collection, i.e. periodic monitoring routine combined with interrupt service, is proposed. The supporting technology such as routing mechanism, slot allocation principles for wireless end device and data aggregation was also designed. A routing method, which combines least-hop routing protocol of node remaining energy and tree protocol, is proposed. Besides, node address recycling strategy was also proposed. The experiment results carried out both in the laboratory and underground coal mine show that the designed system can monitor coal mine environment parameters effectively.",
        "keywords": [
            "Data aggregation",
            "Multi-parameters monitoring",
            "Routing mechanism",
            "Slot allocation",
            "Wireless sensor network"
        ],
        "authors": [
            {
                "name": "Wei Yang",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            },
            {
                "name": "Dezhen Zhang",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            }
        ],
        "venue": "Huazhong Keji Daxue Xuebao (Ziran Kexue Ban)/Journal of Huazhong University of Science and Technology (Natural Science Edition)",
        "year": 2010
    },
    "35LQ4Hlr": {
        "id": "35LQ4Hlr",
        "title": "A Digital Subband Filtering Predistorter for TETRA System",
        "abstract": "This paper proposes a digital adaptive predistorter based on subband filtering for TETRA digital trunked system.Digital subband filtering predistorter divides transmitting signal into several subbands to linearization,the requirement of processing speed is reduction,convergency of adaptive process is enhanced.The subband filtering technology solves the problem of power amplifier's memory characteristic introduced by expansion of signal band,it can be used to improve the work band of digital predistorter.Simulation result of TETRA multi-carrier signal exhibits excellent performance of the proposed predistorter for memoryless power amplifiers and memory power amplifiers,extend the power amplifier linearity range efficiently.",
        "keywords": [
            "subband filtering",
            "digital predistorter",
            "power amplifier linearization"
        ],
        "authors": [
            {
                "name": "ZHANG Qin",
                "org": "School of Electronics and Information Engineering,Beijing Jiaotong University,Beijing "
            },
            {
                "name": "SUN Xin",
                "org": "School of Electronics and Information Engineering,Beijing Jiaotong University,Beijing "
            },
            {
                "name": "YANG Wei",
                "org": "School of Electronics and Information Engineering,Beijing Jiaotong University,Beijing "
            }
        ],
        "venue": "Signal Processing",
        "year": 2010
    },
    "Gd4CUUII": {
        "id": "Gd4CUUII",
        "title": "Simulation analysis on adaptive modulation based STBC-MC-CDMA systems",
        "abstract": "G2, G3, H3 three space-time block codes (STBC) were combined with MC-CDMA respectively to form STBC-MC-CDMA wireless communication systems. Then, adaptive modulation techniques were applied to the three systems. The symbol error rates (SER) of the three STBC-MC-CDMA systems were simulated and compared under Rayleigh fading channel. Simulation results show that under the same channel conditions, the SER performance of G3 system with 1/2 coding rate is best among the three systems, the full-speed coding rate G2 system performs worst, and the SER performance of H3 system with 3/4 coding rate is between G2 and G3 system.",
        "keywords": [
            "Adaptive modulation",
            "Multicarrier code division multiple access (MC-CDMA)",
            "Space-time block codes (STBC)",
            "Spectrum efficiency"
        ],
        "authors": [
            {
                "name": "ZuoMin Wu",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            },
            {
                "name": "Wei Yang",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            }
        ],
        "venue": "Xitong Fangzhen Xuebao / Journal of System Simulation",
        "year": 2010
    },
    "m3zlFFZ0": {
        "id": "m3zlFFZ0",
        "title": "Research on the implement mechanism of EPON VoD QoS multicast based on utility",
        "abstract": "Non-guaranteed QoS and low benefit are essential problems when VoD runs in IP network. Based on network priority, mass SLA priority, as well as economic priority of multicast service of VoD in EPON, a QoS priority utility algorithm (utility priority) is introduced for multicast. When congestion is occurring, the network resources are re-allocated among multicast group according to their utility priority. This measure can not only reduce bandwidth requirement and packet loss, but also can increase bandwidths benefit by converging them on the higher value services. By turning disorderly and variable-length Ethernet frame into orderly and constant-length one, the delay jitter of VoD packet is reduced. The result of simulation well verifies its merits.",
        "keywords": [
            "EPON",
            "Multicast",
            "QoS",
            "VoD"
        ],
        "authors": [
            {
                "name": "ZHANG Jin-Yu",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            },
            {
                "name": "Li Liu",
                "org": "New Jersey Institute of Technology(New Jersey Institute of Technology,New Jersey Inst of Technology),Newark,United States"
            },
            {
                "name": "Wei Yang",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            }
        ],
        "venue": "Jisuanji Xuebao/Chinese Journal of Computers",
        "year": 2010
    },
    "DGAM9xcL": {
        "id": "DGAM9xcL",
        "title": "Nodes access mechanism of grid network for underground coal mine gas monitoring",
        "abstract": "In order to overcome the problem of data collision often occurred when the nodes work at the same channel in the grid wireless sensor network for underground coal mine gas monitoring,a novel wireless nodes access mechanism is proposed in this paper.Firstly,the end devices in wireless sensor network are grouped.Then,the stochastic channel competition is combined with slots allocation.The experiments show that the slot allocation for the grouped nodes,and the transmission of data using CSMA/CA mechanism in the same slot can not only reduce the number of slots and lower data transmission delay,but also can reduce the data transmission collision and save energy.In this way,the reliability and stability of the wireless monitoring network can be improved.",
        "keywords": [
            "gas monitoring",
            "wireless sensor network",
            "wireless nodes access"
        ],
        "authors": [
            {
                "name": "WANG Jianguo",
                "org": "School of Environment and Energy,Inner Mongolia University of Science & Technology,Baotou ,China;Henan Key Laboratory of Coal Mine Methane and Fire Prevention,Henan Polytechnic University,Jiaozuo ,China"
            },
            {
                "name": "ZHANG Dezhen",
                "org": "School of Electronics and Information Engineering,Beijing Jiaotong University,Beijing ,China;Henan Key Laboratory of Coal Mine Methane and Fire Prevention,Henan Polytechnic University,Jiaozuo ,China"
            },
            {
                "name": "YANG Wei",
                "org": "School of Electronics and Information Engineering,Beijing Jiaotong University,Beijing ,China;Henan Key Laboratory of Coal Mine Methane and Fire Prevention,Henan Polytechnic University,Jiaozuo ,China"
            }
        ],
        "venue": "Journal of Liaoning Technical University(Natural Science)",
        "year": 2010
    },
    "qXB5UdvL": {
        "id": "qXB5UdvL",
        "title": "Simulation analysis on adaptive modulation VBLAST-MC-CDMA systems",
        "abstract": "An uplink structure of convolution coded VBLAST-MC-CDMA system was proposed. The adaptive modulation techniques were applied to the system. The thresholds of adaptive modulation were set by simulation. The expected bit error rate (BER) thresholds were settled first, and then according to the BER simulation results, the conversion thresholds of modulation types of the system were determined. The BER performance of the adaptive modulation VBLAST-MC-CDMA system for a given number of users and various number of users was simulated. Simulation results show that adaptive modulation improves the spectrum efficiency of the system in both cases without sacrificing the expected BER performance.",
        "keywords": [
            "Adaptive modulation",
            "Multicarrier code division multiple access (MC-CDMA)",
            "Spectrum efficiency",
            "Vertical Bell Laboratories layered space-time (V-BLAST)"
        ],
        "authors": [
            {
                "name": "WU Zuo-min",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            },
            {
                "name": "Wei Yang",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            }
        ],
        "venue": "Xitong Fangzhen Xuebao / Journal of System Simulation",
        "year": 2010
    },
    "GkYVFQ8v": {
        "id": "GkYVFQ8v",
        "title": "Performance analysis of typical frequency domain spreading multicarrier CDMA modulation in mine tunnel",
        "abstract": "The bit error rate (BER) performance of a typical frequency domain spreading multicarrier CDMA (MCCDMA) modulation in mine tunnel was analyzed based on the established multi-section Nakagami distribution statistical channel model of mine tunnel for wideband radio wave. According to the different root-mean-square (RMS) time delay of wideband radio wave along empty-straight or embranchment mine tunnel,the main parameter restriction condition of MC-CDMA was given so that any sub-carrier experiences frequency-unselective fading channel. Under the circumstances of straight or embranchment mine tunnel the BER performance of a typical MC-CDMA system at 1. 8 GHz and 2. 4 GHz was simulated either at the influence of Doppler frequency offset or impulse interference. Simulation results indicate that the BER performance of the typical MC-CDMA is well in the empty-straight mine tunnel at a lower signal-to-noise (SNR) even though Doppler frequency offset or impulse interference exists. However,a larger SNR is needed for an accepted BER performance in the embranchment mine tunnel whether Doppler frequency offset or impulse interference exists or not.",
        "keywords": [
            "Nakagami distribution",
            "bit error rate(BER)",
            "mine tunnel",
            "typical MC-CDMA modulation"
        ],
        "authors": [
            {
                "name": "YANG Wei",
                "org": " State Key Laboratory of Rail Traffic Control and Safety,Beijing Jiaotong University,Beijing ,China; State Key Laboratory of Coal Resources and Safe Mining,China University of Mining and Technology%%#Beijing%%#,Beijing ,China"
            },
            {
                "name": "ZHOU Qing-qing",
                "org": " State Key Laboratory of Rail Traffic Control and Safety,Beijing Jiaotong University,Beijing ,China; State Key Laboratory of Coal Resources and Safe Mining,China University of Mining and Technology%%#Beijing%%#,Beijing ,China"
            }
        ],
        "venue": "Journal of China Coal Society",
        "year": 2010
    },
    "3JM5QZjN": {
        "id": "3JM5QZjN",
        "title": "Nodes access mechanism of grid network for underground coal mine gas monitoring",
        "abstract": "In order to overcome the problem of data collision often occurred when the nodes work at the same channel in the grid wireless sensor network for underground coal mine gas monitoring, a novel wireless nodes access mechanism is proposed in this paper. Firstly, the end devices in wireless sensor network are grouped. Then, the stochastic channel competition is combined with slots allocation. The experiments show that the slot allocation for the grouped nodes, and the transmission of data using CSMA/CA mechanism in the same slot can not only reduce the number of slots and lower data transmission delay, but also can reduce the data transmission collision and save energy. In this way, the reliability and stability of the wireless monitoring network can be improved.",
        "keywords": [
            "Gas monitoring",
            "Wireless nodes access",
            "Wireless sensor network"
        ],
        "authors": [
            {
                "name": "Jianguo Wang",
                "org": "Inner Mongolia University of Science and Technology(Inner Mongolia University of Science and Technology),Baotou,China"
            },
            {
                "name": "Dezhen Zhang",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            },
            {
                "name": "Wei Yang",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            }
        ],
        "venue": "Liaoning Gongcheng Jishu Daxue Xuebao (Ziran Kexue Ban)/Journal of Liaoning Technical University (Natural Science Edition)",
        "year": 2010
    },
    "17IkCM19": {
        "id": "17IkCM19",
        "title": "An improved location algorithm for RFID system in NLOS environment",
        "abstract": "A novel location algorithm based on geolocation algorithm and LANDMARC algorithm is proposed to improve the location accuracy of Radio Frequency Identification (RFID) system in non-line-of-sight (NLOS) environment. We compare this algorithm with the existing LANDMARC algorithm via two metrics: the mean location error and cumulative location error distribution in line-of-sight (LOS) and NLOS environments, respectively. Numerical simulation results show that the proposed algorithm is very simple, and it gives higher location accuracy in NLOS environment with little performance degradation compared with in LOS environment.",
        "keywords": [
            "rfid",
            "location",
            "mean location error",
            "non-line-of-sight environment",
            "geolocation algorithm",
            "rfid system",
            "radio frequency identification",
            "non-line-of-sight (nlos)",
            "radiofrequency identification",
            "landmarc algorithm",
            "nlos environment",
            "cumulative location error distribution",
            "location accuracy",
            "mean square error methods",
            "cumulant",
            "radio frequency",
            "measurement uncertainty",
            "numerical simulation",
            "wireless communication",
            "degradation",
            "mobile communication",
            "non line of sight",
            "geology",
            "mathematical model",
            "accuracy",
            "signal processing"
        ],
        "authors": [
            {
                "name": "Junhui Zhao",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            },
            {
                "name": "Cong Zhao",
                "org": "Ministry of Education China(Ministry of Education),Beijing,China"
            },
            {
                "name": "Wei Yang",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            }
        ],
        "venue": "Wireless and Optical Communications Conference",
        "year": 2010
    },
    "SO0nHHFM": {
        "id": "SO0nHHFM",
        "title": "Research on the Implement Mechanism of EPON VoD QoS Multicast Based on Utility: Research on the Implement Mechanism of EPON VoD QoS Multicast Based on Utility",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Jin-Yu ZHANG",
                "org": ""
            },
            {
                "name": "Li LIU",
                "org": ""
            },
            {
                "name": "Wei YANG",
                "org": ""
            }
        ],
        "venue": "Chinese Journal of Computers",
        "year": 2010
    },
    "A8xtsqY6": {
        "id": "A8xtsqY6",
        "title": "Design and Simulative Implementation of Wireless Navigation System for Underground Coal Mine",
        "abstract": "In order to enhance the ability of safety production,deal with emergency,and improve managing efficiency,a wireless navigation system for workers and mobile equipments in underground coal mines was designed based on digital mine integrated wireless local access network.According to the Basic Server Set Identification(BSSI) of Access Points(APs) and Received Signal Strength Indication(RSSI) of navigational devices,workers and equipments in the navigation system can be located.By the use of embedded Geographic Information Systems(eGIS) development platform,called eSuperMap,and the WinCE embedded operating system,location-based navigation of workers and mobile equipments in underground coal mine can be achieved.The function of electronic map manipulation,information inquiry,path analysis and navigation was developed,and the results were demonstrated on the platform of Pocket PC 2003 simulator,which showed the feasibility of the system.These works lay a solid foundation for the further development of wireless navigation system in underground coal mine.",
        "keywords": [
            "navigation system",
            "Underground coal mine",
            "Embedded Geographic Information System",
            "wireless local access network(WLAN)"
        ],
        "authors": [
            {
                "name": "LIU Yan-bing",
                "org": "Key Laboratory of All Optical Network and Advanced Telecommunication Network,Ministry of Education,Beijing Jiaotong University,Beijing , China;State Key Laboratory of Coal Resources and Safe Mining,China University of Mining and Technology,Beijing ,China"
            },
            {
                "name": "YANG Wei",
                "org": "Key Laboratory of All Optical Network and Advanced Telecommunication Network,Ministry of Education,Beijing Jiaotong University,Beijing , China;Henan Key Laboratory of Coal Mine Methane and Fire Prevention,Henan Polytechnic University,Jiaozuo ,China"
            },
            {
                "name": "LI Lin-tao",
                "org": "Key Laboratory of All Optical Network and Advanced Telecommunication Network,Ministry of Education,Beijing Jiaotong University,Beijing , China"
            },
            {
                "name": "WANG Shu-guang",
                "org": "Key Laboratory of All Optical Network and Advanced Telecommunication Network,Ministry of Education,Beijing Jiaotong University,Beijing , China"
            }
        ],
        "venue": "Journal of Taiyuan University of Technology",
        "year": 2010
    },
    "wkl8xLda": {
        "id": "wkl8xLda",
        "title": "Multi-parameters monitoring underground coal mine environment using mesh-structured wireless sensor networks",
        "abstract": "In order to overcome the shortcomings of wireless sensor networks for single parameter monitoring in coal mines,a multi-parameters monitoring system for coal mine environment based on mesh structured wireless sensor network is proposed.Multi-kinds of sensors in a wireless node were adopted in the system,such that the integrated monitoring for coal mine environment parameters was achieved.By this way,the premonition information of accident can be caught and analyzed in time,so that coal mine accidents can be avoided significantly.The mode of multi-parameters collection,i.e.periodic monitoring routine combined with interrupt service,is proposed.The supporting technology such as routing mechanism,slot allocation principles for wireless end device and data aggregation was also designed.A routing method,which combines least-hop routing protocol of node remaining energy and tree protocol,is proposed.Besides,node address recycling strategy was also proposed.The experiment results carried out both in the laboratory and underground coal mine show that the designed system can monitor coal mine environment parameters effectively.",
        "keywords": [
            "multi-parameters monitoring",
            "wireless sensor network",
            "data aggregation",
            "slot allocation",
            "routing mechanism"
        ],
        "authors": [
            {
                "name": "Yang Wei",
                "org": "State Key Laboratory of Rail Traffic Control and Safety,Beijing Jiaotong University,Beijing ,China;State Key Laboratory of Coal Resources and Safe Mining,China University of Mining and Technology,Beijing ,China"
            },
            {
                "name": "Zhang Dezhen",
                "org": "State Key Laboratory of Rail Traffic Control and Safety,Beijing Jiaotong University,Beijing ,China;Patent Examination Cooperation Center,State Intellectual Property Office,Beijing ,China"
            }
        ],
        "venue": "Journal of Huazhong University of Science and Technology(Natural Science Edition)",
        "year": 2010
    },
    "4cr9lBMk": {
        "id": "4cr9lBMk",
        "title": "Design on Date Terminal of Wireless Local Access Network in Underground Coal Mine",
        "abstract": "Based on the comprehensive wireless local access network system of the digital mine,the wireless data terminal of the underground mine was researched and developed.The hardware platform based on ARM9 processor and the operation system with the embedded Linux were selected for the wireless data terminal.The main structure of the terminal software included four parallel threads,which would have the short message sending and receiving,equipment control,personal warning,environment parameter's monitoring and other functions.Those function threads could be communicated with the PC computer at the main control terminal with the Socket programming.The self definited message format could be applied to have a joint sharing of the multi thread data and to design the form of the communication messages for the applied layer in favorable to the message sending and receiving.The wireless data terminal was actually tested and measured in coal mine underground roadway in order to have the short message sending and receiving,equipment control and other functions.The feasibility of the system hardware and software design was approved.",
        "keywords": [
            "underground coal mine",
            "multi threads",
            "embedded Linux",
            "wireless local access network(WLAN)"
        ],
        "authors": [
            {
                "name": "ZHAO Yan-lei",
                "org": "Ministry of Education' Key Lab of All Optical Network and Advanced Telecommunication Network,Beijing Jiaotong University,Beijing ,China;State Key Lab of Coal Resources and Safe Mining,China University of Mining and Technology%%#Beijing%%#,Beijing ,China"
            },
            {
                "name": "YANG Wei",
                "org": "Ministry of Education' Key Lab of All Optical Network and Advanced Telecommunication Network,Beijing Jiaotong University,Beijing ,China;State Key Lab of Coal Resources and Safe Mining,China University of Mining and Technology%%#Beijing%%#,Beijing ,China"
            },
            {
                "name": "WANG Shu-guang",
                "org": "Ministry of Education' Key Lab of All Optical Network and Advanced Telecommunication Network,Beijing Jiaotong University,Beijing ,China"
            },
            {
                "name": "TIAN Hong-xian",
                "org": "Ministry of Education' Key Lab of All Optical Network and Advanced Telecommunication Network,Beijing Jiaotong University,Beijing ,China"
            }
        ],
        "venue": "Coal Science and Technology",
        "year": 2010
    },
    "uE8g9vsX": {
        "id": "uE8g9vsX",
        "title": "Underground integrated localization technology in mines based on RSSI",
        "abstract": "To improve productive efficiency and enhance safety protection level for mines by achieving wireless personnel tracking and locomotive locating underground, based on the Received Signal Strength Indictor (RSSI) of the Access Point (AP), the integrated wireless location algorithm is introduced to achieve the requirements in this article. It is proved by measurement that this method could meet the requirements of mine underground wireless locating fully at the precision of within 3 meters. It also overcomes the shortage of Radio Frequency Identification (RFID) technology which only can perform the function of identifying and information recording applied currently in underground of mines.",
        "keywords": [
            "Mine underground",
            "RSSI",
            "Wireless locating",
            "WLAN"
        ],
        "authors": [
            {
                "name": "Hongxian Tian",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            },
            {
                "name": "Wei Yang",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            }
        ],
        "venue": "Liaoning Gongcheng Jishu Daxue Xuebao (Ziran Kexue Ban)/Journal of Liaoning Technical University (Natural Science Edition)",
        "year": 2010
    },
    "GNx1QFkM": {
        "id": "GNx1QFkM",
        "title": "Robust time-domain OFDM timing offset estimation based on PN sequence under multipath channels",
        "abstract": "A novel timing offset estimation scheme for orthogonal frequency division multiplex (OFDM) systems is proposed in this paper, which can eliminate the ambiguity of the first arriving path estimation in multipath channels. The timing of the first arriving path is determined by detecting the first falling edge of the sliding window of the correlation result. A predefined threshold is adopted to validate the presence of the first path. Simulation results show that the proposed scheme can provide more precise timing offset estimation than existing approaches. © 2010 IEEE.",
        "keywords": [
            "ofdm",
            "timing offset",
            "training sequences",
            "ofdm modulation",
            "time domain",
            "sliding window",
            "estimation theory"
        ],
        "authors": [
            {
                "name": "Junhui Zhao",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            },
            {
                "name": "Wei Yang",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            },
            {
                "name": "Rongtao Xu",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            }
        ],
        "venue": "2010 6th International Conference on Wireless Communications, Networking and Mobile Computing, WiCOM 2010",
        "year": 2010
    },
    "Ca6LiCyp": {
        "id": "Ca6LiCyp",
        "title": "Simulation Analysis on Adaptive Modulation Based STBC-MC-CDMA Systems",
        "abstract": "G2 ,G 3 ,H 3 three space-time block codes (STBC) were combined with MC-CDMA respectively to form STBC- MC-CDMA wireless communication systems.Then,adaptive modulation techniques were applied to the three systems.The symbol error rates (SER) of the three STBC-MC-CDMA systems were simulated and compared under Rayleigh fading channel.Simulation results show that under the same channel conditions,the SER performance of G 3 system with 1/2 coding rate is best among the three systems,the full-speed coding rate G 2 system performs worst,and the SER performance of H 3 system with 3/4 coding rate is between G 2 and G 3 system.",
        "keywords": [
            "space-time block codes (STBC)",
            "multicarrier code division multiple access (MC-CDMA)",
            "adaptive modulation",
            "spectrum efficiency"
        ],
        "authors": [
            {
                "name": "WU Zuo-min",
                "org": "State Key Laboratory of Rail Traffic Control and Safety,Beijing Jiaotong University,Beijing ,China;National Mobile Communications Research Laboratory,Southeast University,Nanjing ,China"
            },
            {
                "name": "YANG Wei",
                "org": "State Key Laboratory of Rail Traffic Control and Safety,Beijing Jiaotong University,Beijing ,China;National Mobile Communications Research Laboratory,Southeast University,Nanjing ,China"
            }
        ],
        "venue": "Journal of System Simulation",
        "year": 2010
    },
    "bMJLT377": {
        "id": "bMJLT377",
        "title": "Performance analysis of typical frequency domain spreading multicarrier CDMA modulation in mine tunnel",
        "abstract": "The bit error rate (BER) performance of a typical frequency domain spreading multicarrier CDMA (MC-CDMA) modulation in mine tunnel was analyzed based on the established multi-section Nakagami distribution statistical channel model of mine tunnel for wideband radio wave. According to the different root-mean-square (RMS) time delay of wideband radio wave along empty-straight or embranchment mine tunnel, the main parameter restriction condition of MC-CDMA was given so that any sub-carrier experiences frequency-unselective fading channel. Under the circumstances of straight or embranchment mine tunnel the BER performance of a typical MC-CDMA system at 1.8 GHz and 2.4 GHz was simulated either at the influence of Doppler frequency offset or impulse interference. Simulation results indicate that the BER performance of the typical MC-CDMA is well in the empty-straight mine tunnel at a lower signal-to-noise (SNR) even though Doppler frequency offset or impulse interference exists. However, a larger SNR is needed for an accepted BER performance in the embranchment mine tunnel whether Doppler frequency offset or impulse interference exists or not.",
        "keywords": [
            "Bit error rate (BER)",
            "Mine tunnel",
            "Nakagami distribution",
            "Typical MC-CDMA modulation"
        ],
        "authors": [
            {
                "name": "Wei Yang",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            },
            {
                "name": "Qingqing Zhou",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            }
        ],
        "venue": "Meitan Xuebao/Journal of the China Coal Society",
        "year": 2010
    },
    "ZQ30ie3u": {
        "id": "ZQ30ie3u",
        "title": "Performance analysis of modified MC-CDMA modulation used in mine tunnel",
        "abstract": "The bit error rate(BER) performance of a modified frequency domain spreading multicarrier CDMA(MC-CDMA) modulation used in mine tunnel was analyzed based on the typical MC-CDMA.The main system parameters of the modified MC-CDMA were also given so that any sub-carrier experiences frequency-unselective fading channel in main tunnel.In the simulation,the data rates of users were assumed to be 10 Mb/s and 20 Mb/s,and the central carrier frequencies were assumed to be 1.8 GHz and 2.4 GHz,respectively.The results show that the number and data rates of users generally affect the BER performance more than that of the impulse interference or Doppler frequency offset.When the number of users is more than ten in an area,the error floor of BER performance will generally occur at 20 dB signal-noise-ratio(SNR) for the modified MC-CDMA.",
        "keywords": [
            "bit error rate(BER)",
            "mine tunnel",
            "modified MC-CDMA modulation"
        ],
        "authors": [
            {
                "name": "YANG Wei",
                "org": "State Key Laboratory of Rail Traffic Control and Safety,Beijing Jiaotong University,Beijing ,China;State Key Laboratory of Coal Resources and Safe Mining, China University of Mining & Technology,Beijing ,China"
            },
            {
                "name": "ZHOU Qing-qing",
                "org": "State Key Laboratory of Rail Traffic Control and Safety,Beijing Jiaotong University,Beijing ,China;State Key Laboratory of Coal Resources and Safe Mining, China University of Mining & Technology,Beijing ,China"
            },
            {
                "name": "ZHANG Yu",
                "org": "State Key Laboratory of Rail Traffic Control and Safety,Beijing Jiaotong University,Beijing ,China;State Key Laboratory of Coal Resources and Safe Mining, China University of Mining & Technology,Beijing ,China"
            }
        ],
        "venue": "Journal of China University of Mining & Technology",
        "year": 2011
    },
    "J1zBy8RF": {
        "id": "J1zBy8RF",
        "title": "Integrated attenuation model and BER performance analysis of typical wireless transmission technologies in mine tunnel",
        "abstract": "According to the wireless transmission characteristics in mine tunnels, a tunnel integrated attenuation model was proposed.The attenuation model is composed of two parts: large-scale fading, including pass-loss and shadowing, and small-scale fading, including multi-path and Doppler shift.The accuracy of the proposed model was supported by the match between analytical results and testing data.Based on the integrated attenuation model, the bit error rate(BER) performance by distance of many transmission technologies including Orthogonal Frequency Division Multiplexing(OFDM), Multiple Carrier Code Division Multiple Access(MC-CDMA), MC-DS-CDMA, DS-CDMA and MT-CDMA, were simulated.Simulation results indicate that spread frequency(SF) systems, e.g. MC-CDMA, have better performances in the case of short distances.When the distance is increased, especially before the breakpoint of the model, the BER performances of those SF systems are dramatically declined because of the increased multi-path time delay.By contrast, OFDM system can effectively overcome multi-path fading, leading to a better BER performance in the case of long distance.Therefore, OFDM technique is suitable for the long distance communication in mine tunnels, while SF based techniques are appropriate for short distance environment.",
        "keywords": [
            "Bit error rate(BER)",
            "Integrated attenuation model",
            "Mine tunnel",
            "Multiple Carrier Code Division Multiple Access(MC-CDMA)",
            "Orthogonal Frequency Division Multiplexing(OFDM)"
        ],
        "authors": [
            {
                "name": "Yu Zhang",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            },
            {
                "name": "Wei Yang",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            }
        ],
        "venue": "Meitan Xuebao/Journal of the China Coal Society",
        "year": 2011
    },
    "CejzjlEL": {
        "id": "CejzjlEL",
        "title": "Design of Pilot Signals in OFDM Systems",
        "abstract": "This paper deals with the channel estimation technology applied to orthogonal frequency division multiplexing(OFDM) systems and proposes a novel method to design the optimal pilot pattern.In this method,first,the spacing in the time and the frequency domains between two pilot symbols are determined respectively according to the maximum multi-path delay and Doppler frequency shift.Then,all possible pilot patterns are listed by using the exhaustive method.Finally,the optimal pilot pattern is obtained according to the mean square error between the estimated and the actual channels.In addition,the proposed method is applied to a long-term evolution(LTE) system to verify its correctness and effectiveness,and the superiority of the optimal pilot pattern is verified by simulation curves.From the simulated results,it is found that,as compared with the system using the original LTE pilot pattern,the system using the optimal pattern is of higher BER(Bit Error Rate) performance under the Vehicular Test A channel.",
        "keywords": [
            "long-term evolution",
            "pilot design",
            "orthogonal frequency division multiplexing",
            "exhaustive method",
            "mean square error"
        ],
        "authors": [
            {
                "name": "Yang Wei",
                "org": "State Key Laboratory of Rail Traffic Control and Safety,Beijing Jiaotong University,Beijing ,China;National Mobile Communications Research Laboratory,Southeast University,Nanjing ,Jiangsu,China"
            },
            {
                "name": "Sun Le",
                "org": "State Key Laboratory of Rail Traffic Control and Safety,Beijing Jiaotong University,Beijing ,China;National Mobile Communications Research Laboratory,Southeast University,Nanjing ,Jiangsu,China"
            },
            {
                "name": "Xu Chang-long",
                "org": "National Mobile Communications Research Laboratory,Southeast University,Nanjing ,Jiangsu,China"
            }
        ],
        "venue": "Journal of South China University of Technology(Natural Science Edition)",
        "year": 2011
    },
    "O1WjZw3V": {
        "id": "O1WjZw3V",
        "title": "Research on emergency rescue communication and exploration system underground",
        "abstract": "Mining disasters are happened frequently in recent years. Because of odious underground environment and insufficiency emergency rescue equipments, the first aid for lives and property is strongly affected at the golden rescue time when accidents are happened. According to the special environment and requirements for emergency rescue communication system after disasters, the underground emergency rescue communication and remote controlling exploration system integrated in wireless MESH network and xDSL technology is issued in this article. This system is integrated by wireless environmental monitoring, wireless voice communication, wireless video communication, wireless remote controlling and exploration function, etc. It is great significant to promote technical level of mines emergency rescue equipments and timely rescue after disaster happening. © 2011 IEEE.",
        "keywords": [
            "emergency communication",
            "mesh network",
            "mine underground",
            "remote exploration"
        ],
        "authors": [
            {
                "name": "Hongxian Tian",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            },
            {
                "name": "Wei Yang",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            }
        ],
        "venue": "Proceedings of 2011 IEEE International Conference on Service Operations, Logistics and Informatics, SOLI 2011",
        "year": 2011
    },
    "brfBKe7P": {
        "id": "brfBKe7P",
        "title": "Low complexity antenna selection algorithms for base-station coordination system",
        "abstract": "Two kinds of antenna selection algorithm one proposed according to the characteristics of base-station coordination system. One is called aggregate channel frobenius norm antenna selection (ACFAS), another one is individual channel frobenius norm antenna selection (ICFAS). The object function of antenna selection in ACFAS is based on the aggregate channel frobenius norm of all of the coordinating base-stations and users, while the object function of ICFAS is based on the individual channel frobenius norm of every base-station and user. With the complexity analysis and system simulations, it is proved that the antenna selection algorithms proposed are capable of reducing the complexity, yet at a cost of system capacity lost. So they are suboptimal algorithms.",
        "keywords": [
            "Antenna selection",
            "Base-station coordination",
            "MIMO systems",
            "Multiuser interference"
        ],
        "authors": [
            {
                "name": "HAN Dong-sheng",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            },
            {
                "name": "Wei Yang",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            }
        ],
        "venue": "Chongqing Daxue Xuebao/Journal of Chongqing University",
        "year": 2011
    },
    "4ZG4rwqZ": {
        "id": "4ZG4rwqZ",
        "title": "Design of pilot signals in OFDM systems",
        "abstract": "This paper deals with the channel estimation technology applied to orthogonal frequency division multiplexing (OFDM) systems and proposes a novel method to design the optimal pilot pattern. In this method, first, the spacing in the time and the frequency domains between two pilot symbols are determined respectively according to the maximum multi-path delay and Doppler frequency shift. Then, all possible pilot patterns are listed by using the exhaustive method. Finally, the optimal pilot pattern is obtained according to the mean square error between the estimated and the actual channels. In addition, the proposed method is applied to a long-term evolution (LTE) system to verify its correctness and effectiveness, and the superiority of the optimal pilot pattern is verified by simulation curves. From the simulated results, it is found that, as compared with the system using the original LTE pilot pattern, the system using the optimal pattern is of higher BER (Bit Error Rate) performance under the Vehicular Test A channel.",
        "keywords": [
            "Exhaustive method",
            "Long-term evolution",
            "Mean square error",
            "Orthogonal frequency division multiplexing",
            "Pilot design"
        ],
        "authors": [
            {
                "name": "Wei Yang",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            },
            {
                "name": "Le Sun",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            },
            {
                "name": "Changlong Xu",
                "org": "Southeast University(Southeast University,Southeast Univ),Nanjing,China"
            }
        ],
        "venue": "Huanan Ligong Daxue Xuebao/Journal of South China University of Technology (Natural Science)",
        "year": 2011
    },
    "pInmfpvZ": {
        "id": "pInmfpvZ",
        "title": "Study on QOS of rescue communication system underground based on 802.11EDCF",
        "abstract": "The mine accident occurs so frequently. The reliability and Quality of Service (QOS) of underground emergency rescue communication system have decisive function on the rescue achievements. This article brings forward to apply 802.11EDCF protocol in MAC layer to underground emergency rescue communication system by analyzing the influence of 802.11 DCF to QOS system which is based on 802.11b/g network. By means of simulating, it is obviously shown that even if the network payload of underground emergency rescue communication system is in high heavy, QOS of audio, video and data traffic category still can be guaranteed based on 802.11EDCF protocol in MAC layer.",
        "keywords": [
            "network payload",
            "qos",
            "mac layer",
            "mine underground",
            "quality of service",
            "802.11 dcf",
            "rescue communication system underground",
            "802.11edcf",
            "802.11edcf protocol",
            "mine accident",
            "rescue achievements",
            "emergency services",
            "computer network reliability",
            "mining industry",
            "access protocols",
            "reliability",
            "802.11b/g network",
            "underground communication",
            "emergency communication",
            "underground emergency rescue communication system",
            "wireless lan",
            "qos system",
            "decisive function",
            "wireless sensor networks",
            "wireless sensor network",
            "wireless communication",
            "protocols",
            "communication system",
            "payloads"
        ],
        "authors": [
            {
                "name": "Hongxian Tian",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            },
            {
                "name": "Wei Yang",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            }
        ],
        "venue": "Microwave, Antenna, Propagation, and EMC Technologies for Wireless Communications",
        "year": 2011
    },
    "8nlbLC3Y": {
        "id": "8nlbLC3Y",
        "title": "Performance analysis of modified MC-CDMA modulation used in mine tunnel",
        "abstract": "The bit error rate (BER) performance of a modified frequency domain spreading multicarrier CDMA (MC-CDMA) modulation used in mine tunnel was analyzed based on the typical MC-CDMA. The main system parameters of the modified MC-CDMA were also given so that any sub-carrier experiences frequency-unselective fading channel in main tunnel. In the simulation, the data rates of users were assumed to be 10 Mb/s and 20 Mb/s, and the central carrier frequencies were assumed to be 1.8 GHz and 2.4 GHz, respectively. The results show that the number and data rates of users generally affect the BER performance more than that of the impulse interference or Doppler frequency offset. When the number of users is more than ten in an area, the error floor of BER performance will generally occur at 20 dB signal-noise-ratio (SNR) for the modified MC-CDMA.",
        "keywords": [
            "Bit error rate (BER)",
            "Mine tunnel",
            "Modified MC-CDMA modulation"
        ],
        "authors": [
            {
                "name": "Wei Yang",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            },
            {
                "name": "Qingqing Zhou",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            },
            {
                "name": "Yu Zhang",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            }
        ],
        "venue": "Zhongguo Kuangye Daxue Xuebao/Journal of China University of Mining and Technology",
        "year": 2011
    },
    "UMmRcQ5s": {
        "id": "UMmRcQ5s",
        "title": "M-dimensional space-time error correction code theory for switch node based on omnidirectional radiation of electromagnetic wave",
        "abstract": "In wireless communication field,the omnidirectional radiation of electromagnetic wave in free space is always considered as a big shortcoming,nevertheless,it can be used to improve the performace of wireless communication system in network entironment.Here,we consider that M nodes use a switch node to exchang their information in a wireless network.Differert from the conventional method,the switch node will take the joint coding method for the M independent information,then transmit the same codeword to all M nodes simultaneously through the omnidirectional radiation.For the novel network code,the mathematical definition of the M-dimension space-time error correction code is proposed,and some theorems about its performance are proved to lay a foundation to construct good codebooks.The redundancy of time and space domain is added to the novel codebook at the same time,and the efficiency of the transmit power is improved,so we can design high-rate codebook with good error detection and correction capability.Moreover,the complexity of its decoding algorithm can be reduced,owing to the distributed data processing.Here,we emphasize that contrary to one's intuition,our proposed codebook reveals that it is in general not correct to take the rate of codebook which has the error detection and correction capability to be less than 1.",
        "keywords": [
            "M-dimension space-time error correction code",
            "omnidirectional radiation",
            "wireless communication network",
            "switch node"
        ],
        "authors": [
            {
                "name": "Yang Wei",
                "org": "State Key Laboratory of Rail Traffic Control and Safety,Beijing Jiaotong University,Beijing ,China"
            },
            {
                "name": "Xu Chang-Long",
                "org": "State Key Laboratory of Integrated Service Networks,Xidian University,Xi'an ,China"
            }
        ],
        "venue": "Acta Physica Sinica",
        "year": 2011
    },
    "mVm1Odcq": {
        "id": "mVm1Odcq",
        "title": "Limited quantization feedback design based on error correction in base station coordination system",
        "abstract": "This paper proposes a limited quantization feedback mechanism based on error revising according to the characteristics of base-station coordination system. In this mechanism, the channel quantization process is divided into many steps. The number of the steps equals the number of coordinating base stations. Each quantization step corrects the errors in the previous step. From the complexity analysis and system simulations, it is concluded that the new mechanism reduces quantization complexity with very small degradation in the performance as compared to the existing global feedback mechanisms. It improves the system performance with very little increase in complexity as compared to the existing individual feedback mechanisms. The proposed mechanism provides a good tradeoff between complexity and system performance.",
        "keywords": [
            "Base-station coordination",
            "Limited feedback",
            "Multiuser interference",
            "Pre-encoding"
        ],
        "authors": [
            {
                "name": "HAN Dong-sheng",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            },
            {
                "name": "Wei Yang",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            },
            {
                "name": "XU Chang-long",
                "org": "Southeast University(Southeast University,Southeast Univ),Nanjing,China"
            }
        ],
        "venue": "Yingyong Kexue Xuebao/Journal of Applied Sciences",
        "year": 2011
    },
    "R28vLRQt": {
        "id": "R28vLRQt",
        "title": "Research on wireless video encoding algorithm for underground based on background registration and motion segmentation",
        "abstract": "Regarding to the specialty that the background picture keeps unchangeable with perspective motion objects varying for wireless video monitoring of underground mines, the motion segmentation encoding based on background registration algorithm is brought forward in this article. In this motion segmentation algorithm, each frame for wireless underground video encoding is segmented by motion objects and background, then, they are processed and transmitted according to separated algorithm regulations. Furthermore, because of low illumination and image blurring, the image enhanced algorithm is integrated into the encoding process to enhance the main motion objects to improve the subject quality. At last, the real time transmitted motion object and local saved background image is integrated together to show on the terminal monitoring screen. By this algorithm, the complexity of video encoding and code rate is reduced with high definition video sequences.",
        "keywords": [
            "background registration",
            "mine underground",
            "motion segmentation",
            "video encoding"
        ],
        "authors": [
            {
                "name": "Hongxian Tian",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            },
            {
                "name": "Yang Wei",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            }
        ],
        "venue": "IET Conference Publications",
        "year": 2011
    },
    "Zo7bA8fd": {
        "id": "Zo7bA8fd",
        "title": "MU-MIMO downlink scheduling algorithm with limited feedback",
        "abstract": "Low complexity schedule algorithm with fewer users was proposed for the downlink of multiuser multiple input multiple output (MU-MIMO) system with limited feedback zero-forcing (ZF) precoding. Taking the lower bound function of system throughput as the objective function, the proposed algorithm selected users by maximizing the lower bound value. In this way, multi-user diversity gain was obtained and the system throughput increased. According to the fact that feedback linearly increases with the numbers of users, the algorithm's feedback rate was decreased based on the threshold feedback. Simulation results show that the throughput of the system is effectively improved with this algorithm, and with proper threshold feedback the total feedback rate is declined without any negative effects on the system.",
        "keywords": [
            "Feedback",
            "Multiple input multiple output (MIMO) systems",
            "Multiuser channels",
            "Scheduling algorithms",
            "Threshold feedback",
            "Zero-forcing precoding"
        ],
        "authors": [
            {
                "name": "Dongsheng Han",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            },
            {
                "name": "Wei Yang",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            }
        ],
        "venue": "Huazhong Keji Daxue Xuebao (Ziran Kexue Ban)/Journal of Huazhong University of Science and Technology (Natural Science Edition)",
        "year": 2011
    },
    "swV4HSna": {
        "id": "swV4HSna",
        "title": "Management for Farmland Environment Monitoring WSN Based on the Internet of Things",
        "abstract": "In the farmland environment monitoring WSN(Wireless Sensor Network) ,the network nodes had limited electric quantity and processing power.Thus,an integrated network management scheme was proposed from four aspects of topology management,location management,energy management and fault management,monitoring and managing the network health.In order that users could remotely monitor and manage the wireless sensor monitoring network,a remote monitoring and management platform was developed,which consisted of a background database and a front-end monitoring and management software.Test results showed that the proposed network management scheme could monitor network health in real time and diagnosis network anomalies in time,ensuring network's normal operation and datum's real-time transmission;The developed remote monitoring and management platform had good man-machine interface,fully function and stable performance,realizing remote management for the wireless sensor monitoring network and effective monitoring for the farmland environment.",
        "keywords": [
            "network management",
            "wireless sensor network(WSN)",
            "monitoring and management platform",
            "farmland environment monitoring",
            "MapX",
            "internet of things(IOT)"
        ],
        "authors": [
            {
                "name": "Liu Yang",
                "org": " School of Electronics and Information Engineering,Beijing Jiaotong University,Beijing ; Institute of Agriculture Information,Chinese Academy of Agricultural Sciences,Beijing "
            },
            {
                "name": "Yang Wei",
                "org": " School of Electronics and Information Engineering,Beijing Jiaotong University,Beijing ; Institute of Agriculture Information,Chinese Academy of Agricultural Sciences,Beijing "
            }
        ],
        "venue": "Chinese Agricultural Science Bulletin",
        "year": 2011
    },
    "EwppdHC6": {
        "id": "EwppdHC6",
        "title": "RNTI Allocation Schemes for User Equipments in LTE System",
        "abstract": "Physical Downlink Control Channel (PDCCH) is used to signal dynamic resource assignment information in Long Term Evolution (LTE) system. In the presence of numerous active UEs, their control channel resource location based on PDCCH blind decoding mechanism is determined by the Radio Network Temporary Identifier (RNTI) which is allocated to UEs by eNodeB when they first access to the cell. Choosing RNTI properly can improve UEs' system performance. In this paper, we proposed three RNTI allocation schemes: RNTI continuous allocation scheme, RNTI table allocation scheme and RNTI random allocation scheme. We also developed two simulation models to evaluate our RNTI allocation schemes. The simulation results prove that RNTI table allocation scheme is better than other two allocation schemes both in eliminating conflict probability and increasing CCE utilization ratio.",
        "keywords": [
            "ue system performance",
            "cce utilization ratio",
            "rnti continuous allocation scheme",
            "conflict probabilityelimination",
            "rnti random allocation scheme",
            "physical downlink control channel",
            "active ue",
            "rnti table allocation scheme",
            "signal dynamic resource assignment information",
            "channel coding",
            "user equipments",
            "enodeb",
            "pdcch blind decoding mechanism",
            "simulation model",
            "control channel resource location",
            "rnti allocation scheme",
            "rnti allocation",
            "long term evolution",
            "lte",
            "pdcch",
            "radio network temporary identifier",
            "lte system",
            "long term evolution system",
            "decoding",
            "conflict probability",
            "blind decoding",
            "probability"
        ],
        "authors": [
            {
                "name": "Xiaoli Chen",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            },
            {
                "name": "Wei Yang",
                "org": "Beijing Jiaotong Daxue(Beijing Jiaotong University,Northern Jiaotong University),Beijing,China"
            },
            {
                "name": "Changlong Xu",
                "org": "Southeast University(Southeast University,Southeast Univ),Nanjing,China"
            },
            {
                "name": "Youngil Kim",
                "org": "Wireless System Research Group of ETRI(Wireless System Research Group of ETRI),,South Korea"
            }
        ],
        "venue": "Wireless Communications, Networking and Mobile Computing",
        "year": 2012
    },
    "68Zd2EWB": {
        "id": "68Zd2EWB",
        "title": "Bench and full scale study of removal effect and mutagenicity on Mesocyclops Leukarti with chlorine dioxide",
        "abstract": "Mesocyclops Leukarti of zooplankton propagates excessively in eutrophic water body and it can not be effectively inactivated by the conventional process in drinking waterworks for its special surface structure. In this paper, a study of removal efficiency on Mesocyclops Leukarti with chlorine dioxide in a drinking waterworks was performed. Bench scale results showed that chlorine dioxide is more effective against Mesocyclops Leukarti. And Mesocyclops Leukarti could be effectively removed from water by 1.0 mg/L chlorine dioxide preoxidation cooperated with the conventional process during the full scale study. The chlorite, by-product of prechlorine dioxide, was constant at 0.45 mg/L after filtration, which was lower than the critical value of the USEPA. GC-MS examination and Ames test showed that the quantity of organics and the mutagenicity in the water treated by chlorine dioxide is obviously less than that of prechlorination.",
        "keywords": [
            "Bench scale study",
            "Chlorine dioxide",
            "Full scale study",
            "Mesocyclops Leukarti",
            "Preoxidation",
            "Water treatment"
        ],
        "authors": [
            {
                "name": "ZUO Jin-long",
                "org": "Harbin University of Commerce(Harbin University of Commerce),Harbin,China"
            },
            {
                "name": "Wei Yang",
                "org": "Harbin University of Commerce(Harbin University of Commerce),Harbin,China"
            },
            {
                "name": "LIU Ya-nan",
                "org": "Donghua University(Donghua University ^),Shanghai,China"
            },
            {
                "name": "Tao Lin",
                "org": "Harbin Institute of Technology(Harbin Institute of Technology,Harbin Inst. of Technol.),Harbin,China"
            }
        ],
        "venue": "Journal of Donghua University (English Edition)",
        "year": 2006
    },
    "i28Rc3Lc": {
        "id": "i28Rc3Lc",
        "title": "CONTROLLING THMs YIELDS BY ENHANCING PRECHLORINATION WITH POTASSIUM PERMANGANATE COMPOSITE",
        "abstract": "The laboratory-scale and pilot-scale experiments were conducted to investigate the efficiency of controlling trihalomethanes(THMs) yields by combined preoxidation,which was carried out by potassium permanganate composite(PPC) and chlorine using a typical contaminated resource water in northern China.The laboratory-scale studies showed that,The yields of THMs was reduced 14.1% by the addition of appropriate PPC(dosage as 1.0mg·l~(-1)) during prechlorination process,and the THMs yields was reduced as the pH(decreased),furthermore,at pH 6.0,the PPC addition resulted in substantial reduction of THMs yields;The pilot-scale experiments indicated that,the THMs yields in filtered water with combined preoxidation was(reduced) 47.9% in comparing with prechlorination; Moreover,the results of simulated distribution tests(SDS tests)also showed that,the THMs-SDS yields during combined preoxidation was reduced 17.2% than prechlorination.Therefore,the combined preoxidation by chlorine and PPC may reduce the THMs yields,and improve the chemistry safety of drinking water.",
        "keywords": [
            "chlorine",
            "trihalomethanes.",
            "potassium permanganate composite"
        ],
        "authors": [
            {
                "name": "YANG Wei",
                "org": " School of Municipal and Environmental Engineering,Harbin Institute of Technology,Harbin,,China; Department of Environmental Engineering,Harbin University of Commerce,Herbin,,China"
            },
            {
                "name": "CHEN Jie",
                "org": " Suzhou Litree Ultra-Fitration Membrane Technology Co.LTD,Suzhou,,China"
            },
            {
                "name": "TAO Hui",
                "org": " School of Municipal and Environmental Engineering,Harbin Institute of Technology,Harbin,,China"
            },
            {
                "name": "HAN Hong-da",
                "org": " Tianjin Waterworks Group Company Ltd,Tianjin,,China"
            },
            {
                "name": "LI Gui-bai",
                "org": " School of Municipal and Environmental Engineering,Harbin Institute of Technology,Harbin,,China"
            }
        ],
        "venue": "Environmental Chemistry",
        "year": 2006
    },
    "yDvhyvhT": {
        "id": "yDvhyvhT",
        "title": "Study on Controlling Disinfection by-product with Potassium Permanganate Composite and Chlorine",
        "abstract": "The experiments were carried out on controlling trihalomethanes(THMs) by potassium permanganate composite(PPC) and chlorine,with a raw polluted water sample from a city in northern China.The results indicated that the yields of THMs was reduced 14.1% by the PPC addition of 1.0mg/L during prechlorination process,the THMs yields was reduced with decreasing pH,furthermore,under conditions of pH 6.0,the addition of PPC resulted in obvious reduction of THMs yields.And the results of simulated distribution tests(SDS tests) still showed that the THMs-SDS yields with combined preoxidation was reduced 17.2% than with prechlorination.Therefore,the combined preoxidation by chlorine and PPC could reduce the THMs yields efficiently.",
        "keywords": [
            "chlorine",
            "preoxidation",
            "PPC",
            "disinfection by-product"
        ],
        "authors": [
            {
                "name": "YANG Wei",
                "org": "Department of Environmental Engineering,Harbin University of Commerce,Harbin ,China;College of Municipal and Environmental Engineering,Harbin Institute of Technology,Harbin ,China"
            }
        ],
        "venue": "Chemistry and Adhesion",
        "year": 2007
    },
    "zS1XfdgI": {
        "id": "zS1XfdgI",
        "title": "Interfacial property and coagulation efficiency of amorphous hydrated manganese dioxide",
        "abstract": "Coagulation experiment on the simulated raw water treatment using amorphous hydrated manganese dioxide was carried out in laboratory scale,the effects of it on coagulation of raw water with different turbidity were discussed;though various testing techniques,the said hydrated manganese dioxide particles was characterized and analyzed from aspects of specific surface area of particles,characteristics of interfacial functional group,phase of particles and so on,the coagulation mechanism of hydrated manganese dioxide was discussed.The results of the test showed that: the said hydrated manganese dioxide had aboundant surface hydroxyl radical and its specific surface area was 154.7 m2/g,it was an amorphous hydrate and showed outstanding property on pollutant adsorption;it had excellent coagulation performance to the simulated raw water when the dosage was 1-2 mg/L,and exhibited very good efficiency on decreasing turbidity of filtrated water,The mechanisms of the said hydrated manganese dioxide removing turbidity were adsorbing-bridging and entrapping-settling.",
        "keywords": [
            "interfacial property",
            "amorphous hydrated manganese dioxide",
            "chemical composition",
            "coagulation"
        ],
        "authors": [
            {
                "name": "YANG Wei",
                "org": "Department of Environmental Engineering,Harbin University of Commerce,Harbin ,China"
            }
        ],
        "venue": "Industrial Water & Wastewater",
        "year": 2007
    },
    "WgjyqVPQ": {
        "id": "WgjyqVPQ",
        "title": "Removal of Cd(Ⅱ) from Raw Water by Hydrated Manganese Dioxide",
        "abstract": "The effects of removal of Cd(Ⅱ) from raw water with hydrated manganese dioxide produced by reduction of KMnO4 were studied by coagulation experiments.The effects of pH value and turbidity of raw water on removal of Cd(Ⅱ) were investigated and the possible mechanism were discussed.The results showed that the hydrated manganese dioxide had excellent effect of removing Cd(Ⅱ) from raw water.The removal rate of Cd(Ⅱ) reached 95% with 3mg/L hydrated manganese dioxide.So the hydrated manganese dioxide was a kind of effective water treatment reagent for removing Cd(Ⅱ).",
        "keywords": [
            "cadmium(Ⅱ)",
            "Hydrated manganese dioxide",
            "coagulation"
        ],
        "authors": [
            {
                "name": "YANG Wei",
                "org": "Department of Environmental Engineering,Harbin University of Commerce,Harbin ,China"
            }
        ],
        "venue": "Chemistry and Adhesion",
        "year": 2007
    },
    "MmjqjL7k": {
        "id": "MmjqjL7k",
        "title": "Study on Humic Acid Removal by Hydrous Manganese Dioxide Coagulation",
        "abstract": "In order to further discover the removing pollutant efficiency in water of the hydrous manganese dioxide,the efficiency of removal humic acid of hydrous manganese dioxide which was prepared by reduction of potassium permanganate was studied by jar coagulation tests with the CODMn,TOC and UV254 as the index.The possible mechanism of removal organic matter of hydrous manganese dioxide was also investigated.The results showed that the removal rate of CODMn,TOC and UV254 were 15.25 %,24.07% and 38.0% respectively when the dosage of hydrous manganese dioxide was 6mg·L-1.It concluded that this kind of hydrous manganese dioxide had better effect of removal humic acid and UV254 compared with traditional coagulants.",
        "keywords": [
            "Hydrous manganese dioxide",
            "humic acid",
            "coagulation"
        ],
        "authors": [
            {
                "name": "YANG Wei",
                "org": "Department of Environmental Engineering,Harbin University of Commerce,Harbin ,China"
            }
        ],
        "venue": "Chemistry and Adhesion",
        "year": 2008
    },
    "dwNdxadb": {
        "id": "dwNdxadb",
        "title": "Ultrasonic Extraction of Baicalin from Scutellaria Baicalensis Residue",
        "abstract": "In order to study the value of Scutellaria baicalensis residue,the active component(Baicalin) was first extracted by ultrasonic technology from Scutellaria baicalensis residue.The single factor tests about the concentration of solvent and ultrasonic extraction time etc.were studied.The orthogonal experiment was used for optimal technology parameter selection.The results showed that 15 times volume of ethyl alcohol which concentration is 70% and 50min ultrasonic extraction at 20℃ were the optimum technology condition.Then about 6.0 percent Baicalin can be extracted at the optimum condition from Scutellaria baicalensis residue.The conclusion is that some active component such as Baicalin is still in Scutellaria baicalensis residue,Scutellaria baicalensis residue can be used to resources again.",
        "keywords": [
            "Orthogonal experiment",
            "ultrasonic extraction",
            "Scutellaria baicalensis residue",
            "Baicalin"
        ],
        "authors": [
            {
                "name": "YANG Wei",
                "org": "Department of Environmental Engineering,.Harbin University of Commerce,Harbin,China"
            }
        ],
        "venue": "Chemistry and Adhesion",
        "year": 2008
    },
    "aNivGLDw": {
        "id": "aNivGLDw",
        "title": "Primary Tests on Organic Pollutants Removal by Hydrous Manganese Dioxide from Source Water",
        "abstract": "In order to study the effect of removing micro-organic pollutants in source water by hydrous manganese dioxide,with using CODMn、DOC and UV254 as the index,the jar tests were conducted to evaluate the effect of removing organic pollutants in Songhua River by hydrous manganese dioxide which was prepared by reduction of potassium permanganate.The possible mechanism of removing organic matter by hydrous manganese dioxide was investigated.The results showed an obvious effect of removing organic pollutants in Songhua River water by hydrous manganese dioxide in low dosage(1~3mg/L).The index of CODMn,DOC and UV254 had excellent correlation.It was concluded that this kind of hydrous manganese dioxide had better effect of removing micro-organic pollutants compared with traditional coagulants.The conclusion would be important to practical engineering of purifying water.",
        "keywords": [
            "Hydrous manganese dioxide",
            "organic pollutants",
            "coagulation"
        ],
        "authors": [
            {
                "name": "YANG Wei",
                "org": "Department of Environmental Engineering,Harbin University of Commerce,Harbin,China"
            }
        ],
        "venue": "Chemistry and Adhesion",
        "year": 2008
    },
    "LfjdOphT": {
        "id": "LfjdOphT",
        "title": "Study on Assessing Effect of Biomass-fired Cogeneration Plant on Atmosphere",
        "abstract": "To assess the environmental feasibility,the technical process of biomass-fired cogeneration plant as well as its advantages and disadvantages compared with coal power plant were analyzed.Assessment of effect of biomass-fired generation on atmosphere was conducted.The results predicted that the emission concentrations of soot,SO2 and NO2 would be 11.63mg/m3,200.3mg/m3 and 378.7mg/m3 respectively,which were all far below that of coal power plant.The daily and hourly average concentrations of SO2 and NO2 at different conditions and at different locations were also much lower than that of coal power plant.It shows that biomass-fired power plant has an obvious advantage in environmental friendship.",
        "keywords": [
            "biomass",
            "Environmental impact assessment",
            "integrated evaluation",
            "power plant",
            "atmospheric pollution"
        ],
        "authors": [
            {
                "name": "SU Rong-jun",
                "org": "Teaching & Research section of Environment Engineering,Harbin University of Commerce,Harbin ,China"
            },
            {
                "name": "YANG Wei",
                "org": "Teaching & Research section of Environment Engineering,Harbin University of Commerce,Harbin ,China"
            },
            {
                "name": "CHE Chun-bo",
                "org": "Teaching & Research section of Environment Engineering,Harbin University of Commerce,Harbin ,China"
            },
            {
                "name": "WANG Jun-xia",
                "org": "Teaching & Research section of Environment Engineering,Harbin University of Commerce,Harbin ,China"
            }
        ],
        "venue": "Sichuan Environment",
        "year": 2008
    },
    "IhqedIYF": {
        "id": "IhqedIYF",
        "title": "Factors influencing ammonia removal of biological activated filter in drinking water treatment",
        "abstract": "The factors influencing ammonia removal of biological activated filter (BAF) and the mechanisms were discussed on pilot-scale basis by using modified settling tank effluent. The results showed that the organic content of influent and filter media size influenced ammonia removal of BAF significantly. When using the effluent of settling tank as the influent of BAF, the ammonia removal percentage of BAF-1 (filter media size range of carbon 0.8-1.2 mm) reached 97%; as 2 mg·L -1 of peptone, 2 mg·L -1 of beef extract and 2 mg·L -1 of glucose were added to the influent, only 51.0% of influent ammonia was removed due to the competition of heterotrophic bacteria for oxygen and space. On the other hand, the ammonia removal efficiency of BAF-1 was 1.5%-16.7% higher than that of BAF-2 (filter media size range of carbon 1.0-2.0 mm). Almost complete ammonia removal was achieved by BAF-1 when influent ammonia concentration was less than 1.60 mg·L -1. As influent ammonia concentration increased gradually, the ammonia removal performance decreased because of the lack of dissolved oxygen. The ammonia removal of BAF-1 was enhanced as pre-aeration for the influent was performed. The influence of filter flow rate for ammonia removal was negligible. Backwashing was beneficial to ammonia removal of BAF-1 in this study.",
        "keywords": [
            "Ammonia",
            "Backwashing",
            "Biological activated filter (BAF)",
            "Filter media size",
            "Filter rate",
            "Organic content",
            "Pre-aeration"
        ],
        "authors": [
            {
                "name": "Wei Yang",
                "org": "Harbin University of Commerce(Harbin University of Commerce),Harbin,China"
            },
            {
                "name": "Jiayu Tian",
                "org": "Harbin Institute of Technology(Harbin Institute of Technology,Harbin Inst. of Technol.),Harbin,China"
            },
            {
                "name": "Guibai Li",
                "org": "Harbin Institute of Technology(Harbin Institute of Technology,Harbin Inst. of Technol.),Harbin,China"
            }
        ],
        "venue": "Huagong Xuebao/Journal of Chemical Industry and Engineering (China)",
        "year": 2008
    },
    "ZcZcvsfv": {
        "id": "ZcZcvsfv",
        "title": "The Effects of Typical Nitrogenous Compounds on Haloacetonitriles Production and Chlorine Demand in Drinking Water Chlorination",
        "abstract": "The haloacetonitriles(HANs) production during the process of filtered water chlorination and the effects of chlorine dosage and pH were studied.Glycine,cysteine,lysine,leucine,aspartic acid and methylamine were chosen as the typical nitrogenous compounds,and their effects on HANs production and chlorine demand were studied.The results showed that HANs production was directly proportional to chlorine dosage and inversely proportional to pH;UFC test showed the HANs production of ambient filtered water was 11.2μg·L-1;the nitrogenous compounds would enhance the HANs production which was affected by their characteristics and concentration;the enhance effect rank order was as follow: aspartic acid(36.0μg·L-1) > glycine(17.2μg·L-1) ≈ methylamine(17.0μg·L-1) > lysine(14.0μg·L-1) ≈ leucine(13.8μg·L-1) ≈ cysteine(13.6μg·L-1);the nitrogenous compounds could also increase the chlorine demand which was controlled by their characteristics and concentration;the increase of chlorine demand caused by most of nitrogenous compounds was linear with their concentrations.",
        "keywords": [
            "nitrogenous compounds",
            "haloacetonitriles",
            "Chlorination",
            "chlorine demand"
        ],
        "authors": [
            {
                "name": "TAO Hui",
                "org": "College of Municipal and Environmental Engineering,Harbin Institute of Technology,Harbin ,China"
            },
            {
                "name": "YANG Wei",
                "org": "Department of Environmental Engineering,Harbin University of Commerce,Harbin "
            },
            {
                "name": "WANG Ling",
                "org": "College of Environmental Engineering,Anhui University of Architecture,Hefei ,China"
            },
            {
                "name": "CHEN Zhong-lin",
                "org": "College of Municipal and Environmental Engineering,Harbin Institute of Technology,Harbin ,China"
            },
            {
                "name": "LI Gui-Bai",
                "org": "College of Municipal and Environmental Engineering,Harbin Institute of Technology,Harbin ,China"
            }
        ],
        "venue": "Chemistry and Adhesion",
        "year": 2008
    },
    "VrJCBU2p": {
        "id": "VrJCBU2p",
        "title": "Coagulative Characteristics and Mechanism of Fresh Manganese Dioxide",
        "abstract": "This paper uses the potassium permanganate and the sodium sulfite compound reducing agent to make fresh manganese dioxide and processes each kind of turbidity raw water with it,inspects this fresh manganese dioxide's coagulate efficiency,the influencing factor and possible mechanism to reduce turbidity.The result indicates that this preparation has rich superficial hydroxyl,bigger specific surface and higher chemical adsorption activeness.In addition,under lower throws(2 mg/L),it has the remarkable coagulation potency and the best coagulation pH value scopes vary from 7 to 9.This mechanism of fresh manganese dioxide which coagulates and eliminates the muddy mainly adsorbs the bridging function.",
        "keywords": [
            "coagulate efficiency",
            "fresh manganese dioxide",
            "sodium sulfite compound reducing agent",
            "surface chemistry"
        ],
        "authors": [
            {
                "name": "LIU Can-bo",
                "org": "School of Environmental and Municipal Engineering,Qingdao Technological University,Qingdao ,China"
            },
            {
                "name": "LV Mou",
                "org": "School of Environmental and Municipal Engineering,Qingdao Technological University,Qingdao ,China"
            },
            {
                "name": "YANG Wei",
                "org": "Department of Environmental Engineering,Harbin University of Commerce,Harbin ,China"
            },
            {
                "name": "LI Gui-bai",
                "org": "School of Municipal & Environmental Engineering,Harbin Institute of Technology,Harbin ,China"
            }
        ],
        "venue": "Journal of Qingdao Technological University",
        "year": 2008
    },
    "BH3rlAFY": {
        "id": "BH3rlAFY",
        "title": "Contaminant Removal Mechanism of Colloidal Hydrated Manganese Dioxide Produced by Composite Reducing Agent",
        "abstract": "The contaminant removal efficiency by colloidal hydrated manganese dioxide produced by potassium permanganate and composite reducing agent was investigated by jar test.The structure and shape of colloidal hydrated manganese dioxide particle was observed by transmission electron microscope(TEM),and the charge of its floc and the infrared(IR) characteristic of its particle were also studied.The contaminant removal mechanism was discussed.The results show that the excellent coagulation efficiency can be achieved at low dosage of colloidal hydrated manganese dioxide.The diameter of the colloidal hydrated manganese dioxide particle is about 10 nm,it has abundant surface hydroxyl,and the charge of its floc shows electronegative.The adsorption bridging and entrapping-sweeping functions are the main mechanism of coagulation,and the characteristic adsorption function of particle surface is the main mechanisms of organics removal.",
        "keywords": [
            "colloidal hydrated manganese dioxide",
            "contaminant removal mechanism",
            "coagulation"
        ],
        "authors": [
            {
                "name": "YANG Wei",
                "org": "Department of Environmental Engineering,Harbin University of Commerce,Harbin ,China"
            }
        ],
        "venue": "China Water & Wastewater",
        "year": 2008
    },
    "C1KgJ5bo": {
        "id": "C1KgJ5bo",
        "title": "Strategic Contemplation: Development of Modern TCM Theory",
        "abstract": "Based on a range of modern TCM theory events, including awarded research findings, research projects, academic papers, experts interview, and meeting presentations, this paper contemplates the following issues: 1) the advanced nature and historic accomplishments of TCM theory; 2) importance of today's TCM theory development; 3) an overview of today's development of TCM theory; 4) major existing problems in TCM theory development; 5) general trends of TCM theory development; 6) strategic goals and thinking lines of TCM theory development; 7) strategic focus and main missions of TCM theory development; and 8) supporting measures for such development.",
        "keywords": [
            "development goals",
            "thinking lines",
            "TCM theory"
        ],
        "authors": [
            {
                "name": "Pan Guijuan",
                "org": "The Institute of Basic Theory of TCM, China Academy of Chinese Medical Sciences, "
            },
            {
                "name": "Yu Zhimin",
                "org": "The Institute of Basic Theory of TCM, China Academy of Chinese Medical Sciences, "
            },
            {
                "name": "Liu Yang",
                "org": "The Institute of Basic Theory of TCM, China Academy of Chinese Medical Sciences, "
            },
            {
                "name": "Yang Wei",
                "org": "The Institute of Basic Theory of TCM, China Academy of Chinese Medical Sciences, "
            },
            {
                "name": "Jin Xianglan",
                "org": "The Institute of Basic Theory of TCM, China Academy of Chinese Medical Sciences, "
            },
            {
                "name": "Zhang Huamin",
                "org": "The Institute of Basic Theory of TCM, China Academy of Chinese Medical Sciences, "
            },
            {
                "name": "Li Haiyu",
                "org": "The Institute of Basic Theory of TCM, China Academy of Chinese Medical Sciences, "
            },
            {
                "name": "Luo Weifang",
                "org": "The Institute of Basic Theory of TCM, China Academy of Chinese Medical Sciences, "
            },
            {
                "name": "Zhang Yupeng",
                "org": "The Institute of Basic Theory of TCM, China Academy of Chinese Medical Sciences, "
            },
            {
                "name": "Liu Zhaihua",
                "org": "The Institute of Basic Theory of TCM, China Academy of Chinese Medical Sciences, "
            },
            {
                "name": "Wang Zuoyuan",
                "org": "The Institute of Basic Theory of TCM, China Academy of Chinese Medical Sciences, "
            }
        ],
        "venue": "World Science and Technology-Modernization of Traditional Chinese Medicine and Materia Medica",
        "year": 2007
    },
    "xS10F6L6": {
        "id": "xS10F6L6",
        "title": "SuWen Based Study of YunQi Theory",
        "abstract": "Category, or theoretical domain and basic notion, is a key to the successful establishment of a TCM theoretical system in NeiJing. As an important part of NeiJing, YunQi theory has attracted numerous arguments. This paper discusses the issues of category, based on research findings on SuWen. We believe that Suwen works on the impacts of Mother Nature on life, though it deals with the harmonization of WuYun and LiuQi. In this context, YunQi theory covers an extended category, focusing on variations of nature and its impacts on life (both humans and other creatures). The theory is made up of the core seven chapters, a highly enriched reflection of the basic nature of natural variations.",
        "keywords": [
            "seven particular thesis",
            "c",
            "YunQi theory",
            "kernel notion"
        ],
        "authors": [
            {
                "name": "Yang Wei",
                "org": " The Institute of Basic Theory of TCM, China Academy of Chinese Medical Sciences,Beijing "
            },
            {
                "name": "Liu Zhaihua",
                "org": " The Institute of Basic Theory of TCM, China Academy of Chinese Medical Sciences,Beijing "
            },
            {
                "name": "Yu Zheng",
                "org": " The Institute of Basic Theory of TCM, China Academy of Chinese Medical Sciences,Beijing "
            },
            {
                "name": "Zhang Yupeng",
                "org": " The Institute of Basic Theory of TCM, China Academy of Chinese Medical Sciences,Beijing "
            }
        ],
        "venue": "World Science and Technology-Modernization of Traditional Chinese Medicine and Materia Medica",
        "year": 2007
    },
    "cRRWVi4G": {
        "id": "cRRWVi4G",
        "title": "An Overview of Recent Study of YunQi Theory",
        "abstract": "The theory of YunQi is an important part of TCM doctrine. It reveals the relationship between the nature of human body and treating patients with TCM dialectic theory. This paper illustrates the principles of YunQi theory and it's applications, in an attempt to improve both TCM theory and clinical practices. In the past 50 years, some 500 papersand books on the topic have been published in China. Researchers have made detailed and systematic study of both basic theory and its applications in clinical environment, trying to interpret the theory in a scientific manner. Based on research findings, and our understanding of SuWen, we believe that YunQi Theory is an academic theory containing a string of the socalled notions that warrants further investigation.",
        "keywords": [
            "overview",
            "concept of TCM",
            "YunQi Theory",
            "theoretical study"
        ],
        "authors": [
            {
                "name": "Yang Wei",
                "org": "The Institute of Basic Theory of TCM, China Academy of Chinese Medical Sciences,Beijing "
            },
            {
                "name": "Liu Zhaihua",
                "org": "The Institute of Basic Theory of TCM, China Academy of Chinese Medical Sciences,Beijing "
            },
            {
                "name": "Yu Zheng",
                "org": "The Institute of Basic Theory of TCM, China Academy of Chinese Medical Sciences,Beijing "
            },
            {
                "name": "Zhang Yupeng",
                "org": "The Institute of Basic Theory of TCM, China Academy of Chinese Medical Sciences,Beijing "
            }
        ],
        "venue": "World Science and Technology-Modernization of Traditional Chinese Medicine and Materia Medica",
        "year": 2007
    },
    "rvO1lIEU": {
        "id": "rvO1lIEU",
        "title": "Study on Theoretic System of TCM Internal Organs",
        "abstract": "There are contradiction and unity of basic concept,functional structure,and construction method in Theoretic system of internal organs,which has obvious and complicated systematic character.The evaluation of theory model should follow the principles of tracing the root and seeking development to study the character and relationship of Internal organs theoretic system at different stages.And then gradually discover contents and construction principle of Internal organs theoretic system,thus resolve the bottleneck problem which constricts the TCM theory research and clinical development.",
        "keywords": [
            "Internal organs theory",
            "Neijing",
            "theoretic system"
        ],
        "authors": [
            {
                "name": "Yang Wei",
                "org": "TCM Basic Theory Research Institute of China Academy of Chinese Medical Sciences,"
            },
            {
                "name": "Yu Zheng",
                "org": "TCM Basic Theory Research Institute of China Academy of Chinese Medical Sciences,"
            },
            {
                "name": "Liu Zhaihua",
                "org": "TCM Basic Theory Research Institute of China Academy of Chinese Medical Sciences,"
            }
        ],
        "venue": "Journal of Shaanxi College of Traditional Chinese Medicine",
        "year": 2009
    },
    "Js9mIPaA": {
        "id": "Js9mIPaA",
        "title": "Efficient Symmetric Five-Party Quantum State Sharing of an Arbitrary <i>m</i>-Qubit State",
        "abstract": "We present an efficient symmetric scheme for five-party quantum state sharing of an arbitrary m-qubit state with 2m three-particle entangled states. The implementations of this scheme only need to exploit the CNOT gate operations and the\n single-particle measurements, instead of the three-particle GHZ-state measurements, which makes it more convenient in a practical\n application than some previous schemes. In addition, its total efficiency can approach the maximal value in theory.",
        "keywords": [
            "quantum cryptography · quantum secret sharing · quantum state sharing"
        ],
        "authors": [
            {
                "name": "Run-hua Shi",
                "org": "NHPCC, Department of Computer Science and Techology, USTC, Hefei, 230027 China"
            },
            {
                "name": "Liu-sheng Huang",
                "org": "NHPCC, Department of Computer Science and Techology, USTC, Hefei, 230027 China"
            },
            {
                "name": "Wei Yang",
                "org": "NHPCC, Department of Computer Science and Techology, USTC, Hefei, 230027 China"
            },
            {
                "name": "Hong Zhong",
                "org": "School of Computer Science and Technology, Anhui University, Hefei, 230039 China"
            }
        ],
        "venue": "",
        "year": 0
    },
    "dAN65Jul": {
        "id": "dAN65Jul",
        "title": "Quantum Oblivious Transfer Using Tripartite Entangled States",
        "abstract": "Oblivious transfer is an interesting cryptographic task in which one party Alice aims to transfer one of her two bits to the other party Bob, with the assurance that he can choose freely his bit, but is not able to obtain the two bits simultaneously. Bob on the other hand wants to be sure that Alice should not be capable of inferring what bit he has chosen. Quantum oblivious transfer (QOT) scheme outperforms its classical counterpart for its higher security and eavesdropping detecting ability. In this paper, we present a new and novel QOT protocol based on tripartite entangled states, which can be proven to be secure against any quantum attacking strategy allowed by physical laws.",
        "keywords": [
            "interesting cryptographic task",
            "quantum oblivious transfer",
            "party alice",
            "novel qot protocol",
            "cryptographic task",
            "party bob",
            "physical law",
            "qot protocol",
            "classical counterpart",
            "higher security",
            "quantum cryptography",
            "tripartite entangled state",
            "cryptographic protocols",
            "oblivious transfer",
            "tripartite entangled states"
        ],
        "authors": [
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Liusheng Huang",
                "org": ""
            },
            {
                "name": "Yifei Yao",
                "org": ""
            },
            {
                "name": "Zhili Chen",
                "org": ""
            }
        ],
        "venue": "FGCN (1)",
        "year": 2007
    },
    "eJEbeNHI": {
        "id": "eJEbeNHI",
        "title": "Unconditionally secure quantum oblivious transfer",
        "abstract": "As a basic protocol of Secure Multi-party Computation, Oblivious Transfer (OT) is of significant research and application value. Most of previous oblivious transfer protocols in classical environment rely either on public-key cryptography or on additional computational assumptions which will be very vulnerable under quantum mechanics. Based on the characteristics of Bell States, a new quantum oblivious transfer protocol is proposed in this paper. The correctness and security of the protocol are analyzed and proved. The protocol is secure in the presence of noise on the channel and a potential eavesdropper. Comparing with oblivious transfer protocols in classical computational environment, the protocol in this paper is superior in security, soundness and wire-tapping detecting.",
        "keywords": [
            "Bell states",
            "Oblivious transfer",
            "Privacy amplification",
            "Unconditionally secure"
        ],
        "authors": [
            {
                "name": "Wei Yang",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "HUANG Liu-sheng",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "LUO Yong-long",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "CHEN Guo-liang",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            }
        ],
        "venue": "Tien Tzu Hsueh Pao/Acta Electronica Sinica",
        "year": 2007
    },
    "oyK82gy6": {
        "id": "oyK82gy6",
        "title": "Linguistic Steganography Detection Based on Perplexity",
        "abstract": "Linguistic steganography is a technique for hiding information into text carriers. Most of the previous work on linguistic steganography was focused on steganography and there were few researches on steganalysis. Research on attacking methods against linguistic steganography plays an important role in information security (IS) area. In this paper, a linguistic steganography detection algorithm based on perplexity is presented. An experiment to detect text segments generated by linguistic steganography system NICETEXT is carried out. The result of our experiment is pretty promising. The experimental accuracy of our method on classification of generated text and normal text exceeds 99% when text size is larger than 400 bytes. Even for sentences, the experimental accuracy exceeds 85%.",
        "keywords": [
            "attacking methods",
            "nicetext",
            "steganography",
            "text segment detection",
            "important role",
            "text processing",
            "text carrier",
            "language model",
            "linguistic steganography system",
            "normal text",
            "steganalysis",
            "linguistic steganography detection algorithm",
            "linguistic steganography detection",
            "text size",
            "linguistic steganography",
            "hiding information",
            "perplexity",
            "experimental accuracy",
            "text segment",
            "linguistics",
            "information security",
            "training data",
            "classification algorithms",
            "testing",
            "text segmentation",
            "accuracy",
            "data mining"
        ],
        "authors": [
            {
                "name": "Peng Meng",
                "org": ""
            },
            {
                "name": "Liusheng Huang",
                "org": ""
            },
            {
                "name": "Zhili Chen",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Dong Li",
                "org": ""
            }
        ],
        "venue": "Three Gorges",
        "year": 2008
    },
    "bjBTVdVr": {
        "id": "bjBTVdVr",
        "title": "A Statistical Attack on a Kind of Word-Shift Text-Steganography",
        "abstract": "Text-steganography plays an increasingly significant role in covert-communication on Internet. Compared with study on text-steganography, research on text-steganalysis is in its infancy. In this paper, we present a statistical analysis of a kind of word-shift text-steganography by using neighbor difference (length difference of two consecutive spaces). We classify nature PDF documents into two cases serving for our analysis and statistically model word-shift steganographic embedding situations. Our method can reliably detect existence of hidden information. Furthermore, it quantitatively gives estimated embedding rate. The high performance of our method is demonstrated by experiments. Our work will contribute to both text-steganalysis and text-steganography.",
        "keywords": [
            "word-shift text-steganography",
            "nature pdf document",
            "length difference",
            "embedding rate",
            "model word-shift steganographic",
            "statistical analysis",
            "neighbor difference",
            "high performance",
            "consecutive space",
            "hidden information",
            "statistical attack",
            "testing",
            "error probability",
            "statistical model",
            "probability density function",
            "silicon",
            "cryptography",
            "internet"
        ],
        "authors": [
            {
                "name": "Lingjun Li",
                "org": ""
            },
            {
                "name": "Liusheng Huang",
                "org": ""
            },
            {
                "name": "Xinxin Zhao",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Zhili Chen",
                "org": ""
            }
        ],
        "venue": "IIH-MSP",
        "year": 2008
    },
    "fUZEfXxt": {
        "id": "fUZEfXxt",
        "title": "Privacy-Preserving Practical Convex Hulls Protocol",
        "abstract": "Secure multi-party computation has been a hot research topic of cryptograhy for about two decades, and the convex hulls problem is a special case of it. However, the precise convex hulls will certainly expose all vertexes and even bring about unfairness. Therefore the practical approximate convex hulls are in need. In this paper, we summarize and discuss the convex hulls problem, and then we present a more effective new protocol to compute the approximate convex hulls. Furthermore, we analyze the security, communication complexity and efficiency of the protocol, and compare the new scheme with other privacy-preserving convex hulls protocols through simulated experiments. It shows that our privacy-preserving approximate convex hulls protocol is more effective than the previous privacy-preserving ones, and the new protocol is practical enough in many situations. Perfectly keeping privacy preserving and eliminating unfairness are the great advantages of our scheme.",
        "keywords": [
            "new scheme",
            "precise convex hull",
            "privacy-preserving practical convex hulls",
            "convex hulls",
            "secure multi-party computation",
            "data privacy",
            "cryptograhy",
            "effective new protocol",
            "computational geometry",
            "practical enough",
            "approximation",
            "communication complexity",
            "practical approximate convex hull",
            "privacy-preserving convex hulls protocol",
            "approximate convex hulls protocol",
            "new protocol",
            "cryptographic protocols",
            "approximate convex hull",
            "secure multiparty computation",
            "pchp",
            "convex hulls problem",
            "privacy-preserving",
            "simulation experiment",
            "security",
            "convex hull",
            "secure communication",
            "protocols",
            "secure multi party computation",
            "computational modeling",
            "privacy"
        ],
        "authors": [
            {
                "name": "Youwen Zhu",
                "org": ""
            },
            {
                "name": "Liusheng Huang",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Zhili Chen",
                "org": ""
            },
            {
                "name": "Lingjun Li",
                "org": ""
            },
            {
                "name": "Zhenshan Yu",
                "org": ""
            },
            {
                "name": "Yonglong Luo",
                "org": ""
            }
        ],
        "venue": "FCST",
        "year": 2008
    },
    "LUUoxIhQ": {
        "id": "LUUoxIhQ",
        "title": "Linguistic Steganography Detection Using Statistical Characteristics of Correlations between Words",
        "abstract": "Linguistic steganography is a branch of Information Hiding (IH) using written natural language to conceal secret messages. It plays an important role in Information Security (IS) area. Previous work on linguistic steganography was mainly focused on steganography and there were few researches on attacks against it. In this paper, a novel statistical algorithm for linguistic steganography detection is presented. We use the statistical characteristics of correlations between the general service words gathered in a dictionary to classify the given text segments into stego-text segments and normal text segments. In the experiment of blindly detecting the three different linguistic steganography approaches: Markov-Chain-Based, NICETEXT and TEXTO, the total accuracy of discovering stego-text segments and normal text segments is found to be 97.19%. Our results show that the linguistic steganalysis based on correlations between words is promising.",
        "keywords": [
            "statistical characteristic",
            "information hiding",
            "statistical characteristics",
            "text segment",
            "different linguistic steganography approach",
            "information security",
            "linguistic steganography detection",
            "stego-text segment",
            "normal text segment",
            "novel statistical algorithm",
            "linguistic steganography",
            "text segmentation",
            "natural language",
            "markov chain"
        ],
        "authors": [
            {
                "name": "Zhili Chen",
                "org": "National High Performance Computing Center at Hefei, Department of Computer Science and Technology, University of Science and Technology of China, Hefei, China 230027"
            },
            {
                "name": "Liusheng Huang",
                "org": "National High Performance Computing Center at Hefei, Department of Computer Science and Technology, University of Science and Technology of China, Hefei, China 230027"
            },
            {
                "name": "Zhenshan Yu",
                "org": "National High Performance Computing Center at Hefei, Department of Computer Science and Technology, University of Science and Technology of China, Hefei, China 230027"
            },
            {
                "name": "Wei Yang",
                "org": "National High Performance Computing Center at Hefei, Department of Computer Science and Technology, University of Science and Technology of China, Hefei, China 230027"
            },
            {
                "name": "Lingjun Li",
                "org": "National High Performance Computing Center at Hefei, Department of Computer Science and Technology, University of Science and Technology of China, Hefei, China 230027"
            },
            {
                "name": "Xueling Zheng",
                "org": "National High Performance Computing Center at Hefei, Department of Computer Science and Technology, University of Science and Technology of China, Hefei, China 230027"
            },
            {
                "name": "Xinxin Zhao",
                "org": "National High Performance Computing Center at Hefei, Department of Computer Science and Technology, University of Science and Technology of China, Hefei, China 230027"
            }
        ],
        "venue": "Information Hiding",
        "year": 2008
    },
    "s5xJ5VKb": {
        "id": "s5xJ5VKb",
        "title": "Text Information Hiding Detecting Algorithm Based on Statistics",
        "abstract": "Text Information Hiding (TIH) is a technique for embedding secret messages into text carriers. Research on attacking methods against TIH plays an important role in Information Security (IS) area. In this paper, a text information hiding detecting algorithm based on statistical characteristics of correlations between words is presented. An experiment to detect text segments generated by text information hiding system NICETEXT using the algorithm is carried out and a pretty good result is obtained. In the experiment, there are 115 normal text segments and 212 generated text segments detected, and 106 normal segments and 209 generated segments are successfully picked out. Only 9 normal segments and 3 generated segments are mistakenly examined. The accuracy of the detecting reaches as high as 96.3%.",
        "keywords": [
            "N-window mutual information",
            "detecting",
            "correlations between words",
            "information hiding"
        ],
        "authors": [
            {
                "name": "CHEN Zhi-li",
                "org": ""
            },
            {
                "name": "HUANG Liu-sheng",
                "org": ""
            },
            {
                "name": "YU Zhen-shan",
                "org": ""
            },
            {
                "name": "LI Ling-jun",
                "org": ""
            },
            {
                "name": "YANG Wei",
                "org": ""
            }
        ],
        "venue": "Journal of Chinese Computer Systems",
        "year": 2008
    },
    "9ncit0EE": {
        "id": "9ncit0EE",
        "title": "A Practical Three-Dimensional Privacy-Preserving Approximate Convex Hulls Protocol",
        "abstract": "Convex hulls problem is a special case of privacy-preserving geometry problem in the inquiry of secure multi-party computation. In the past, only in two-dimensional space privacy-preserving convex hulls have been investigated, and there is little focus in the three-dimensional space. However, three-dimensional privacy-preserving convex hulls can be applied in many fields, such as researching and exploration of the space, military, corporately finding the union range based on sensitive data from two parties. Approximate convex hulls have more advantages than conventional convex hulls in the theme of secure multi-party computation because it can hide the private points on the vertices. In this paper, we first present a practical privacy-preserving protocol to solve the three dimensional approximate convex hulls problem; we also discuss the correctness, security, and performance of our protocol.",
        "keywords": [
            "privacy-preserving geometry problem",
            "three-dimensional privacy-preserving convex hull",
            "three-dimensional convex hulls",
            "secure multi-party computation",
            "conventional convex hulls",
            "practical privacy-preserving protocol",
            "convex hull",
            "two-dimensional space",
            "three-dimensional space",
            "convex hulls protocol",
            "practical three-dimensional privacy-preserving approximate",
            "approximate convex hull",
            "secure multiparty computation",
            "approximate convex hulls",
            "conventional convex hull",
            "convex hulls problem",
            "approximate convex hulls problem",
            "three-dimensional privacy-preserving approximate convex hulls protocol",
            "security of data",
            "privacy-preserving computational geometry",
            "cryptography",
            "secure multi party computation",
            "space exploration",
            "computational geometry",
            "protocols",
            "detectors",
            "three dimensional",
            "security"
        ],
        "authors": [
            {
                "name": "Dong Li",
                "org": ""
            },
            {
                "name": "Liusheng Huang",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Youwen Zhu",
                "org": ""
            },
            {
                "name": "Yonglong Luo",
                "org": ""
            },
            {
                "name": "Zhili Chen",
                "org": ""
            },
            {
                "name": "Lingjun Li",
                "org": ""
            },
            {
                "name": "Yun Ye",
                "org": ""
            }
        ],
        "venue": "FCST",
        "year": 2008
    },
    "5bS6OkLq": {
        "id": "5bS6OkLq",
        "title": "Attacks on Translation Based Steganography",
        "abstract": "Translation-based steganography (TBS) is a kind of famous text steganography. In this paper, we examine the robustness of TBS and give an effective detection algorithm for TBS. Our algorithm can not only distinguish between natural language text and stego-text which was generated by TBS, but also can distinguish between machine translated text and stego-text. The detection accuracy increases as the text size increases. When the text size is larger than 60 sentences, the detection accuracy is greater than 92%.",
        "keywords": [
            "steganography",
            "tbs(translation-based steganography)",
            "detection algorithm",
            "natural language text",
            "translation based steganography",
            "dmr(degree of machine reversibility)",
            "steganalysis",
            "language translation",
            "text steganography",
            "machine translated text",
            "dmp(degree of machine preference)",
            "natural language processing",
            "text analysis",
            "stego-text",
            "data mining",
            "testing",
            "natural languages",
            "accuracy",
            "machine translation",
            "support vector machines",
            "natural language"
        ],
        "authors": [
            {
                "name": "Peng Meng",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Liusheng Hang",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Wei Yang",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Zhili Chen",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            }
        ],
        "venue": "Beijing",
        "year": 2009
    },
    "M5UoMUoZ": {
        "id": "M5UoMUoZ",
        "title": "An Efficient Multi-secret Sharing Scheme with the Quasi-threshold Multipartite Access Structure",
        "abstract": "In real world, there are many important applications for the secret sharing with the quasi-threshold multipartite access structure. But there was still not a very efficient scheme proposed in the past. In this paper, we combine the multi-secret sharing and the quasi-threshold multipartite access structure, and present an efficient multi-secret sharing scheme with the quasi-threshold multipartite access structure based on Shamirpsilas secret sharing scheme. In this scheme, the participants of any authorized subset can reconstruct multiple secrets by repeatedly using the Lagrange interpolation formula during a sharing process, but any non-authorized subset cannot recover any secret. In addition, the share is the same size of the single shared secret. Thus, it is an efficient and ideal multi-secret sharing scheme with the quasi-threshold multipartite access structure.",
        "keywords": [
            "lagrange interpolation formula",
            "multi-secret",
            "sharing process",
            "efficient scheme",
            "quasi-threshold multipartite access structure",
            "quasithreshold multipartite access structure",
            "single shared secret",
            "multi-secret sharing",
            "cryptography",
            "interpolation",
            "multiple secret",
            "secret sharing scheme",
            "access structure",
            "multisecret sharing scheme",
            "ideal multi-secret sharing scheme",
            "authorized subset",
            "threshold",
            "efficient multi-secret",
            "secret sharing",
            "multipartite",
            "efficient multi-secret sharing scheme",
            "wireless communication",
            "application software",
            "probability density function",
            "security",
            "block codes",
            "computer science",
            "computer networks",
            "polynomials",
            "lagrange interpolation",
            "data mining"
        ],
        "authors": [
            {
                "name": "Runhua Shi",
                "org": ""
            },
            {
                "name": "Liusheng Huang",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Hong Zhong",
                "org": ""
            }
        ],
        "venue": "Networks Security, Wireless Communications and Trusted Computing, 2009. NSWCTC '09. International Conference",
        "year": 2009
    },
    "xyxQZh0o": {
        "id": "xyxQZh0o",
        "title": "Linguistic Steganography Detection Algorithm Using Statistical Language Model",
        "abstract": "Steganography is a technique for embedding secret messages into carriers. Linguistic steganography is a branch of text steganography. Research on attacking methods against linguistic steganography plays an important role in Information Security (IS) area. In this paper, a linguistic steganography detecting algorithm using Statistical Language Model(SLM) is presented. An experiment to detect text segments generated by linguistec steganography systems NICETEXT, TEXTO and Markov-Chain-Based is carried out. The result of our experiment shows when the text segment size is 2K and 5K, the detecting accuracies are found to be 93.9% and 96.3% respectively",
        "keywords": [
            "text segment size",
            "important role",
            "linguistic steganography detection algorithm",
            "linguistec steganography system",
            "text segment",
            "statistical language model",
            "information security",
            "linguistic steganography",
            "text steganography",
            "secret message",
            "computational modeling",
            "data mining",
            "text segmentation",
            "cryptography",
            "steganalysis",
            "markov chain",
            "markov processes",
            "natural language processing",
            "steganography",
            "high performance computing",
            "information technology",
            "training data",
            "testing",
            "classification algorithms",
            "text analysis",
            "computational linguistics",
            "natural languages",
            "perplexity",
            "computer science",
            "statistical analysis",
            "accuracy"
        ],
        "authors": [
            {
                "name": "Peng Meng",
                "org": ""
            },
            {
                "name": "Liusheng Hang",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Zhili Chen",
                "org": ""
            },
            {
                "name": "Hu Zheng",
                "org": ""
            }
        ],
        "venue": "ITCS '09 Proceedings of the 2009 International Conference on Information Technology and Computer Science - Volume 02",
        "year": 2009
    },
    "qzTQJn9k": {
        "id": "qzTQJn9k",
        "title": "A Practical Solution for Privacy-Preserving Approximate Convex Hulls Problem",
        "abstract": "Convex Hulls Problem is a special case of Privacy-preserving Geometry problems in the inquiry of Secure Multi-Party Computation (SMC). It can be applied in military, commercial and many other fields. However, because of the definition's inherent defect, current schemes will inevitably disclose the points on the vertices. In this paper, we proposed the concept of privacy-preserving approximate convex hulls problem and provide a practical protocol which is more secure and efficient than previous convex hulls protocols. We also show that it can be applied to finding the approximate intersection area of two private convex hulls.",
        "keywords": [
            "privacy-preserving geometry problem",
            "secure multi-party computation",
            "data privacy",
            "current scheme",
            "practical protocol",
            "inherent defect",
            "convex hulls protocol",
            "previous convex hulls protocol",
            "practical solution",
            "privacy-preserving approximate convex hulls",
            "approximate convex hull",
            "privacy-preserving geometric computation",
            "approximate intersection area",
            "convex hulls problem",
            "private convex hull",
            "geometry",
            "approximate convex hulls problem",
            "security of data",
            "privacy-preserving approximate convex hulls problem",
            "data mining",
            "cryptography",
            "protocols",
            "secure multi party computation",
            "convex hull",
            "computer security",
            "security",
            "probability density function"
        ],
        "authors": [
            {
                "name": "Dong Li",
                "org": ""
            },
            {
                "name": "Liusheng Huang",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Youwen Zhu",
                "org": ""
            },
            {
                "name": "Yonglong Luo",
                "org": ""
            },
            {
                "name": "Lingjun Li",
                "org": ""
            },
            {
                "name": "Zhili Chen",
                "org": ""
            }
        ],
        "venue": "Communications and Mobile Computing, 2009. CMC '09. WRI International Conference",
        "year": 2009
    },
    "l1F2ztEj": {
        "id": "l1F2ztEj",
        "title": "An Information Hiding Algorithm Based on Double Text Segments",
        "abstract": "Information hiding is a technique that hides secret messages in some carrier during transmission or storage.Carriers in common use include image,audio,video,text documents and so on.Since there is little redundancy in text documents,particularly in plain text documents,information hiding based on plain text documents is much more challenging.Previous algorithms based on plain text documents are all based on a single plain text segment.Therefore,there are many inherent limitations in security of them.In this paper,a novel information hiding algorithm based on double text segments is proposed.The algorithm can enhance the concealment and security of information hiding greatly by choosing a proper hiding form out of many ones and scattering information to places.In addition,the algorithm is so flexible that it can be modified or adjusted according to the certain application scene to fit the practical requirements better.",
        "keywords": [
            "Double text segments",
            "Information hiding",
            "XOR decomposition",
            "Synonym replacement"
        ],
        "authors": [
            {
                "name": "Chen Zhi-li",
                "org": ""
            },
            {
                "name": "Huang Liu-sheng",
                "org": ""
            },
            {
                "name": "Yu Zhen-shan",
                "org": ""
            },
            {
                "name": "Yang Wei",
                "org": ""
            },
            {
                "name": "Chen Guo-liang",
                "org": ""
            }
        ],
        "venue": "Journal of Electronics & Information Technology",
        "year": 2009
    },
    "vjRHmFeV": {
        "id": "vjRHmFeV",
        "title": "Three-party bit commitment based on elliptic curve",
        "abstract": "Bit commitment is a fundamental primitive in secure multi-party computation. It plays an important role in constructions of more complicated multi-party protocols. A new model of bit commitment named three-party bit commitment is proposed in this paper, in which two provers jointly commit a bit to a verifier. The protocol of three-party bit commitment based on elliptic curve cryptography is also given. The scheme is in purely classical means, without restricted assumptions of the computing power imposed on any participant. Moreover, the scheme is proven to be of unconditional security and be immune to channel eavesdropping. The protocol can also be modified easily to realize bit string commitment scheme.",
        "keywords": [
            "Cryptography",
            "Bit commitment(BC)",
            "Three-party model",
            "Elliptic curve(EC)",
            "Unconditionally binding",
            "Unconditionally concealing"
        ],
        "authors": [
            {
                "name": "Yang Wei",
                "org": ""
            },
            {
                "name": "Liusheng Huang",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Qiyan Wang",
                "org": "University of Illinois at Urbana-Champaign(University of Illinois at Urbana-Champaign,Univ. Illinois at Urbana-Champaign,University of Illinois,Univ of Illinois at Urbana-Champaign),Urbana,United States"
            }
        ],
        "venue": "Dianzi Yu Xinxi Xuebao/Journal of Electronics and Information Technology",
        "year": 2009
    },
    "4mEvhJ7q": {
        "id": "4mEvhJ7q",
        "title": "An information hiding algorithm based on double text segments",
        "abstract": "Information hiding is a technique that hides secret messages in some carrier during transmission or storage. Carriers in common use include image, audio, video, text documents and so on. Since there is little redundancy in text documents, particularly in plain text documents, information hiding based on plain text documents is much more challenging. Previous algorithms based on plain text documents are all based on a single plain text segment. Therefore, there are many inherent limitations in security of them. In this paper, a novel information hiding algorithm based on double text segments is proposed. The algorithm can enhance the concealment and security of information hiding greatly by choosing a proper hiding form out of many ones and scattering information to places. In addition, the algorithm is so flexible that it can be modified or adjusted according to the certain application scene to fit the practical requirements better.",
        "keywords": [
            "Double text segments",
            "Information hiding",
            "Synonym replacement",
            "XOR decomposition"
        ],
        "authors": [
            {
                "name": "Zhili Chen",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Liusheng Huang",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Zhenshan Yu",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Wei Yang",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Guoliang Chen",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            }
        ],
        "venue": "Dianzi Yu Xinxi Xuebao/Journal of Electronics and Information Technology",
        "year": 2009
    },
    "yNEo5CIq": {
        "id": "yNEo5CIq",
        "title": "Three New Approaches to Privacy-preserving Add to Multiply Protocol and its Application",
        "abstract": "Privacy-preserving data mining aims at securely extracting knowledge from two or more parties' private data. Secure multi-party computation is the paramount approach to it. In this paper, we study privacy-preserving add and multiply exchanging technology and present three new different approaches to privacy-preserving add to multiply protocol. After that, we analyze and compare the three different approaches about the communication overheads, the computation efforts and the security. In addition, we extend privacy-preserving add to multiply protocol to privacy-preserving adding to scalar product protocol, which is more secure and more useful in the high security situations of privacy-preserving data mining. Meantime, we present a solution for the new protocol.",
        "keywords": [
            "add_and_multiply exchanging technolog",
            "different approach",
            "secure multiparty computation",
            "scalar product protocol",
            "data privacy",
            "high security situation",
            "multiply protocol",
            "privacy-preserving add-to-multiply protocol",
            "multiply exchanging technology",
            "secure multi-party computation",
            "new different approach",
            "privacy-preserving data mining",
            "secure knowledge extraction",
            "-privacy-preserving",
            "communication overhead",
            "add_to_multiply protocol i. introduction",
            "cryptographic protocol",
            "privacy-preserving adding-to-scalar-product protocol",
            "new protocol",
            "privacy-preserving add-and-multiply exchange technology",
            "new approaches",
            "cryptographic protocols",
            "data mining",
            "add_to_multiply protocol",
            "privacy-preserving",
            "scalar product",
            "data security"
        ],
        "authors": [
            {
                "name": "Youwen Zhu",
                "org": ""
            },
            {
                "name": "Liusheng Huang",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Dong Li",
                "org": ""
            },
            {
                "name": "Yonglong Luo",
                "org": ""
            },
            {
                "name": "Fan Dong",
                "org": ""
            }
        ],
        "venue": "WKDD",
        "year": 2009
    },
    "Mmka5vWK": {
        "id": "Mmka5vWK",
        "title": "Steganalysis on Character Substitution Using Support Vector Machine",
        "abstract": "A new steganalysis method is proposed to detect the exists of hiddeninformation using character substitution in texts. This is done byutilizing Support Vector Machine (SVM) as a classifier to classifythe characteristic vector input into SVM. The most important step ofthis detection algorithm is the construction of a propercharacteristic vector. Under the prerequisite that the secret bitsto be embedded are uniformly distributed, the distribution of thecharacters used for hiding data has altered after steganographicprocess, thus the ratio of abnormal characters to normal charactersis different in cover texts and stego texts. Experimental resultsdemonstrate that this method can reliably detect whether there ishidden information in texts. The detection accuracy in experimentreaches as high as 96\\% while the embedding data rate is merely20\\%.",
        "keywords": [
            "support vector machines",
            "support vector machine",
            "text analysis",
            "steganography"
        ],
        "authors": [
            {
                "name": "Xinxin Zhao",
                "org": ""
            },
            {
                "name": "Liusheng Huang",
                "org": ""
            },
            {
                "name": "Lingjun Li",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Zhili Chen",
                "org": ""
            },
            {
                "name": "Zhenshan Yu",
                "org": ""
            }
        ],
        "venue": "WKDD",
        "year": 2009
    },
    "t4BZeB32": {
        "id": "t4BZeB32",
        "title": "Privacy-Preserving Approximate Convex Hulls Protocol",
        "abstract": "Secure multi-party computation has been a research focus for more than two decades. The convex hulls problem is a special case of secure multi-party computation. However, the precise convex hulls will certainly expose every vertex and even bring about unfairness. As a result, the practical approximate convex hulls are in need. In this paper, we summarize and discuss the convex hulls problem, and then we present a new more effective protocol to privately find the approximate convex hulls. Furthermore, we analyze the correctness, security, efficiency and performance of the protocol, and compare the new scheme with other privacy-preserving convex hulls protocols. We show that the privacy-preserving approximate convex hulls protocol is more effective than the previous privacy-preserving convex hulls ones, and the new protocol is practical enough in many aspects. Perfectly keeping privacy preserving and eliminating unfairness are the great advantages of our scheme.",
        "keywords": [
            "precise convex hull",
            "protocols",
            "secure multiparty computation",
            "effective protocol",
            "approximation",
            "secure multi-party computation",
            "convex hulls problem",
            "practical approximate convex hull",
            "privacy-preserving convex hulls protocol",
            "approximate convex hulls protocol",
            "new protocol",
            "previous privacy-preserving convex hull",
            "privacy-preserving approximate convex hulls",
            "approximate convex hull",
            "privacy-preserving approximate convex hulls protocol",
            "privacy-preserving",
            "security of data",
            "educational technology",
            "sliding mode control",
            "probability density function",
            "secure multi party computation",
            "data mining",
            "quantum computing",
            "privacy",
            "computer science education",
            "convex hull",
            "computer science",
            "security"
        ],
        "authors": [
            {
                "name": "Youwen Zhu",
                "org": ""
            },
            {
                "name": "Liusheng Huang",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Dong Li",
                "org": ""
            },
            {
                "name": "Lingjun Li",
                "org": ""
            },
            {
                "name": "Yonglong Luo",
                "org": ""
            },
            {
                "name": "Fan Dong",
                "org": ""
            }
        ],
        "venue": "Education Technology and Computer Science, 2009. ETCS '09. First International Workshop",
        "year": 2009
    },
    "6zkLLrc8": {
        "id": "6zkLLrc8",
        "title": "An Evaluating Scheme for Embedding Security of Natural Language Watermarking",
        "abstract": "Natural language watermarking(NLW) is a kind of digital rights management(DRM) techniques specially designed for natural language documents.Though much work has been done on designing elaborate watermarking algorithms,security or quality of these schemes is only roughly discussed.In this paper,we propose an evaluating scheme for embedding security of NLW,define ideal undetectability,and design ways to construct an inter-proof system for undetectability against specific detector.We also apply this evaluating scheme to some practical NLW systems.",
        "keywords": [
            "Computational indistinguishability",
            "Natural language watermarking",
            "Inter-proof system",
            "computational indistinguishability",
            "Undetectability",
            "inter-proof system",
            "undetectability",
            "Computational model",
            "computational model",
            "natural language watermarking"
        ],
        "authors": [
            {
                "name": "YU Zhen-shan",
                "org": "NHPCC,Depart.of CS.& Tech.,USTC,Hefei Anhui ,China;Suzhou Institute for Advanced Study,USTC,Suzhou jiangsu,China"
            },
            {
                "name": "HUANG Liu-sheng",
                "org": "NHPCC,Depart.of CS.& Tech.,USTC,Hefei Anhui ,China;Suzhou Institute for Advanced Study,USTC,Suzhou jiangsu,China"
            },
            {
                "name": "CHEN Zhi-li",
                "org": "NHPCC,Depart.of CS.& Tech.,USTC,Hefei Anhui ,China;Suzhou Institute for Advanced Study,USTC,Suzhou jiangsu,China"
            },
            {
                "name": "LI ling-jun",
                "org": "NHPCC,Depart.of CS.& Tech.,USTC,Hefei Anhui ,China;Suzhou Institute for Advanced Study,USTC,Suzhou jiangsu,China"
            },
            {
                "name": "YANG Wei",
                "org": "NHPCC,Depart.of CS.& Tech.,USTC,Hefei Anhui ,China;Suzhou Institute for Advanced Study,USTC,Suzhou jiangsu,China"
            },
            {
                "name": "ZHAO Xin-xin",
                "org": "NHPCC,Depart.of CS.& Tech.,USTC,Hefei Anhui ,China;Suzhou Institute for Advanced Study,USTC,Suzhou jiangsu,China"
            }
        ],
        "venue": "Netinfo Security",
        "year": 2009
    },
    "DVE7CDkf": {
        "id": "DVE7CDkf",
        "title": "A P2P Trust Model Based on Trusted Computing",
        "abstract": "Building trust relationships between entities is an important and difficult part in the security needs of P2P networks.By using appropriate assessment tools,traditional trust models can weaken some security threats such as simple deception,an omission,defamation and joint cheating to a certain extent,however they are unable to resist the attacks of Pseudospoofing and Pseudostheft effectively.In this paper,the trusted computing method initiated by Trusted Computing Group(TCG) is introduced into P2P networks,and we propose an efficient scheme on foundation and management of stable and verifiable digital identities of entities.The new designed trust model,using platform attestation technology through the whole process of trust evaluation,perfectly solved security problems of P2P networks.",
        "keywords": [
            "P2P",
            "Platform attestation",
            "Trust evaluation",
            "Trusted computing",
            "DAA",
            "Trusted computing platform"
        ],
        "authors": [
            {
                "name": "HE Li-Bao",
                "org": "NHPCC,Depart.of CS.& Tech.,USTC,Hefei An-hui ,China;Suzhou Institute for Advanced Study,USTC,Suzhou Jiangsu ,China"
            },
            {
                "name": "HUANG Liu-Sheng",
                "org": "NHPCC,Depart.of CS.& Tech.,USTC,Hefei An-hui ,China;Suzhou Institute for Advanced Study,USTC,Suzhou Jiangsu ,China"
            },
            {
                "name": "YANG Wei",
                "org": "NHPCC,Depart.of CS.& Tech.,USTC,Hefei An-hui ,China;Suzhou Institute for Advanced Study,USTC,Suzhou Jiangsu ,China"
            },
            {
                "name": "LUO Yong-Long",
                "org": "NHPCC,Depart.of CS.& Tech.,USTC,Hefei An-hui ,China;Suzhou Institute for Advanced Study,USTC,Suzhou Jiangsu ,China"
            }
        ],
        "venue": "Netinfo Security",
        "year": 2009
    },
    "rjAbeFD0": {
        "id": "rjAbeFD0",
        "title": "STBS: a statistical algorithm for steganalysis of translation-based steganography",
        "abstract": "Translation-Based Steganography is a secure text steganographic algorithm. In this paper, we present a novel statistical algorithm for steganalysis of Translation-Based Steganography (STBS). We first show that there are fewer high-frequency words in stegotexts than in normal texts. We then design a preprocessor to refine all the given texts to expand the frequency differences between normal texts and stegotexts. 12 dimensional feature vectors sensitive to frequency are derived from the refined texts. We finally use a SVM classifier to classify given texts to normal texts and stegotexts. A series of experiments is given to demonstrate the performance of STBS.",
        "keywords": [
            "svm classifier",
            "dimensional feature",
            "fewer high-frequency word",
            "secure text steganographic algorithm",
            "translation-based steganography",
            "refined text",
            "frequency difference",
            "normal text",
            "novel statistical algorithm",
            "svm",
            "feature vector",
            "steganalysis",
            "high frequency",
            "natural language"
        ],
        "authors": [
            {
                "name": "Peng Meng",
                "org": "NHPCC, Depart. of CS. & Tech., USTC, Hefei, China"
            },
            {
                "name": "Liusheng Hang",
                "org": "NHPCC, Depart. of CS. & Tech., USTC, Hefei, China and Suzhou Institute for Advanced Study, USTC, Suzhou, China"
            },
            {
                "name": "Zhili Chen",
                "org": "NHPCC, Depart. of CS. & Tech., USTC, Hefei, China and Suzhou Institute for Advanced Study, USTC, Suzhou, China"
            },
            {
                "name": "Yuchong Hu",
                "org": "NHPCC, Depart. of CS. & Tech., USTC, Hefei, China"
            },
            {
                "name": "Wei Yang",
                "org": "NHPCC, Depart. of CS. & Tech., USTC, Hefei, China and Suzhou Institute for Advanced Study, USTC, Suzhou, China"
            }
        ],
        "venue": "Information Hiding",
        "year": 2010
    },
    "t9Kex2zS": {
        "id": "t9Kex2zS",
        "title": "An efficient scheme for multiparty multi-particle state sharing",
        "abstract": "We present an efficient scheme for sharing an arbitrary m-qubit state with n agents. In our scheme, the sender Alice first shares m Bell states with the agent Bob, who is designated to recover the original m-qubit state. Furthermore, Alice introduces n-1 auxiliary particles in the initial state |0〉, applies Hadamard (H) gate and Controlled-Not (CNOT) gate operations on the particles, which make them entangled with one of m particle pairs in Bell states, and then sends them to the controllers (i.e., other n - 1 agents), where each controller only holds one particle in hand. After Alice performing m Bell-basis measurements and each controller a single-particle measurement, the recover Bob can obtain the original unknown quantum state by applying the corresponding local unitary operations on his particles. Its intrinsic efficiency for qubits approaches 100%, and the total efficiency really approaches the maximal value. © Chinese Physical Society and IOP Publishing Ltd.",
        "keywords": [
            "Quantum cryptography",
            "Quantum information",
            "Quantum secret sharing",
            "Quantum state sharing"
        ],
        "authors": [
            {
                "name": "Shi Run-Hua",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Huang Liu-Sheng",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Wei Yang",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Hong Zhong",
                "org": "Anhui University(Anhui University),Hefei,China"
            }
        ],
        "venue": "Communications in Theoretical Physics",
        "year": 2010
    },
    "Pk7dTcw9": {
        "id": "Pk7dTcw9",
        "title": "Improved related-key attack on 7-round AES-128/256",
        "abstract": "In this paper the authors present an attack on 7-round AES-128/256 to improve the known cryptanalysis by changing the order of round transformation , using the alternative representation of the round keys, exploiting the relationship of keys, designing the key difference pattern properly. By using the improved attack method, the complexity is reduced from 2 192 to 2 104 with 2 72 chosen plaintexts, the authors reduce complexity to 2 88 using partial sums. ©2010 IEEE.",
        "keywords": [
            "aes",
            "related-key attack",
            "rijndael",
            "square attack",
            "public key cryptography",
            "partial sums",
            "cryptanalysis",
            "encryption",
            "computer science",
            "schedules",
            "related key attack"
        ],
        "authors": [
            {
                "name": "Jie Cui",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Liusheng Huang",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Hong Zhong",
                "org": "Anhui University(Anhui University),Hefei,China"
            },
            {
                "name": "Wei Yang",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            }
        ],
        "venue": "ICCSE 2010 - 5th International Conference on Computer Science and Education, Final Program and Book of Abstracts",
        "year": 2010
    },
    "eJbl9uOJ": {
        "id": "eJbl9uOJ",
        "title": "Analysis and detection of text steganographic tool-Stegparty",
        "abstract": "Using the idea of probability statistics, a study on Stegparty encode-text was done. After analyzing the characteristics of encode-text, a detecting algorithm based on characteristic lexicons was proposed. The idea possesses favorable commonality and flexibility. It also fits other text steganography based on substitution such as synonyms substitution and punctuation substitution. A detection experiment on Stegparty was carried out. Experimental result shows that the detecting algorithm can achieve an accuracy of 90% even when the embedding ratio is very low (about 0.08%).",
        "keywords": [
            "Characteristic lexicons",
            "Detection",
            "Probability statistics",
            "Steganography",
            "Stegparty"
        ],
        "authors": [
            {
                "name": "Haibo Miao",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Liusheng Huang",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Zhili Chen",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Wei Yang",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            }
        ],
        "venue": "Tongxin Xuebao/Journal on Communications",
        "year": 2010
    },
    "VhWRU4Ym": {
        "id": "VhWRU4Ym",
        "title": "Analysis and Detection of Translation-Based Steganography",
        "abstract": "Translation-Based Steganography(TBS) is a class of text steganography.When translating the same sentence from a natural language to another by different translators,there are normally different translation results.Making use of this property,TBS chooses from different translation results of a sentence according to secrete messages to generate stego-text.Because TBS basically preserves syntactic correctness and semantic coherence,it is comparatively difficulty for traditional detections to detect this method.Our research shows that there exists a detection method for TBS when we know the Machine Translation(MT) set that being used by TBS.So it is crucial important to keep a secret of the MT set.This paper theoretically analyzes the effective of our detection method and gives the detection process and experiment results.Additionally,we propose a method to improve the security of TBS.",
        "keywords": [
            "Degree of machine generated",
            "Degree of machine preference",
            "Degree of machine reversibility",
            "Machine translation",
            "Steganalysis",
            "Steganography"
        ],
        "authors": [
            {
                "name": "Peng Meng",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Liusheng Huang",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "CHEN Zhi-li",
                "org": "NHPCC,Department of Computer Science and Technology,USTC,Hefei,Anhui ,China;Suzhou Institute for Advanced Study,USTC,Suzhou,Jiangsu ,China"
            },
            {
                "name": "YANG Wei",
                "org": "NHPCC,Department of Computer Science and Technology,USTC,Hefei,Anhui ,China;Suzhou Institute for Advanced Study,USTC,Suzhou,Jiangsu ,China"
            },
            {
                "name": "YANG Ming",
                "org": "NHPCC,Department of Computer Science and Technology,USTC,Hefei,Anhui ,China"
            }
        ],
        "venue": "Acta Electronica Sinica",
        "year": 2010
    },
    "zJRonv2L": {
        "id": "zJRonv2L",
        "title": "Quantum secret sharing between multiparty and multiparty with Bell states and Bell measurements",
        "abstract": "We present a quantum secret sharing scheme between multiparty (m members in Group 1) and multiparty (n members in Group 2), and analyze its security. This scheme takes EPR pairs in Bell states as quantum resources. In order\n to obtain the shared key, all members only need to perform Bell measurements, rather than perform any local unitary operation.\n The total efficiency in this scheme approaches 100% as the classical information exchanged is not necessary except for the\n eavesdropping checks.",
        "keywords": [
            "quantum cryptography",
            "quantum information",
            "quantum secret sharing"
        ],
        "authors": [
            {
                "name": "RunHua Shi",
                "org": "National High Performance Computing Center at Hefei, Department of Computer Science and Technology, University of Science and Technology of China, Hefei, 230027 China"
            },
            {
                "name": "LiuSheng Huang",
                "org": "National High Performance Computing Center at Hefei, Department of Computer Science and Technology, University of Science and Technology of China, Hefei, 230027 China"
            },
            {
                "name": "Wei Yang",
                "org": "National High Performance Computing Center at Hefei, Department of Computer Science and Technology, University of Science and Technology of China, Hefei, 230027 China"
            },
            {
                "name": "Hong Zhong",
                "org": "School of Computer Science and Technology, Anhui University, Hefei, 230039 China"
            }
        ],
        "venue": "Science China Physics, Mechanics and Astronomy",
        "year": 2010
    },
    "LjvN8YOw": {
        "id": "LjvN8YOw",
        "title": "GENERAL: An Efficient Scheme for Multiparty Multi-particle State Sharing",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "runhua shi",
                "org": "university of science and technology of china"
            },
            {
                "name": "liusheng huang",
                "org": "university of science and technology of china"
            },
            {
                "name": "wei yang",
                "org": "university of science and technology of china"
            },
            {
                "name": "hong zhong",
                "org": "anhui university"
            }
        ],
        "venue": "Communications in Theoretical Physics",
        "year": 2010
    },
    "USTuqp5l": {
        "id": "USTuqp5l",
        "title": "A general model for trust and reputation systems",
        "abstract": "Trust and reputation systems are widely used in electronic commerce, social network, search engine, and so on. They have become a very important element in cyberspace. However the theoretical research actualities of this field are lagging behind applications. Various existing works are rarely relevant and without consensus. Aiming at the above problems, this paper proposes a general model for trust and reputation systems. The model mainly solves the following basic problems in this field: i) redefine the concepts of trust and reputation and discuss the relationship between them; ii) design and construction of the general model, especially the basic element of trust and reputation systems, and iii) the applications of the general model for trust and reputation systems. According to this work, this paper gets some key results of this field. These results will provide research foundations and framework for the future work.",
        "keywords": [
            "reputation",
            "security",
            "theoretical research",
            "trust",
            "vertical search",
            "e-commerce",
            "trust and reputation systems",
            "general model",
            "research foundations",
            "security of data",
            "e commerce",
            "social network",
            "electronic commerce",
            "search engine",
            "argon"
        ],
        "authors": [
            {
                "name": "Fan Dong",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Liusheng Huang",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Wei Yang",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Youwen Zhu",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Jianfeng Wang",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            }
        ],
        "venue": "ICCSIT), 2010 3rd IEEE International Conference",
        "year": 2010
    },
    "uA2CATKU": {
        "id": "uA2CATKU",
        "title": "Efficient collusion-resisting data aggregation protocol",
        "abstract": "A measurement model was defined to analysis each privacy-preserving data aggregation protocol's ability to resist potential collusion. Then, a new efficient collusion-resisting privacy-preserving data aggregation protocol was proposed. Theoretical analysis and experiment result confirmed the protocol's ability to resist potential collusion and the communication overhead of our scheme is much less than existing protocol's.",
        "keywords": [
            "Collusion",
            "Data aggregation",
            "Privacy-preserving",
            "Wireless sensor networks"
        ],
        "authors": [
            {
                "name": "Youwen Zhu",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Liusheng Huang",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Wei Yang",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Miaomiao Tian",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            }
        ],
        "venue": "Tongxin Xuebao/Journal on Communications",
        "year": 2010
    },
    "ulySJ8gJ": {
        "id": "ulySJ8gJ",
        "title": "An Efficient Collusion Detection Algorithm Based on Concentrative Trust Management Model",
        "abstract": "Collusion is one of the most intractable malicious behaviors in the trust management model.Due to the subjective property of trust value,there is no good method to determine collusion action yet.This paper proposes a collusion detection algorithm for concentrative trust management model by clustering method.A correlative simulation program is designed to test the performance of the algorithm and settings of parameters.We also have a quantitative analysis for it.The simulation results indicate that the method is effective when choosing proper parameters.",
        "keywords": [
            "concentrative trust management model",
            "collusion detection",
            "trust management",
            "clustering"
        ],
        "authors": [
            {
                "name": "DONG Fan",
                "org": "National High Performance Computing Center,Department of Computer Science & Technology,University of Science and Technology of China,Hefei ,China;Suzhou Institute for Advanced Study,University of Science and Technology of China,Suzhou ,China"
            },
            {
                "name": "HUANG Liu-sheng",
                "org": "National High Performance Computing Center,Department of Computer Science & Technology,University of Science and Technology of China,Hefei ,China;Suzhou Institute for Advanced Study,University of Science and Technology of China,Suzhou ,China"
            },
            {
                "name": "WANG Jian-feng",
                "org": "National High Performance Computing Center,Department of Computer Science & Technology,University of Science and Technology of China,Hefei ,China;Suzhou Institute for Advanced Study,University of Science and Technology of China,Suzhou ,China"
            },
            {
                "name": "YANG Wei",
                "org": "National High Performance Computing Center,Department of Computer Science & Technology,University of Science and Technology of China,Hefei ,China;Suzhou Institute for Advanced Study,University of Science and Technology of China,Suzhou ,China"
            },
            {
                "name": "ZHU You-wen",
                "org": "National High Performance Computing Center,Department of Computer Science & Technology,University of Science and Technology of China,Hefei ,China;Suzhou Institute for Advanced Study,University of Science and Technology of China,Suzhou ,China"
            }
        ],
        "venue": "Journal of Chinese Computer Systems",
        "year": 2010
    },
    "hH7e4rAA": {
        "id": "hH7e4rAA",
        "title": "Privacy Preserving Density-Based Outlier Detection",
        "abstract": "Outlier detection can find its tremendous applications in areas such as intrusion detection, fraud detection, and image processing. Among many outlier detection algorithms, LOF is a very important density-based algorithm in which one critical step is to find the k-distance neighbors. In some privacy preserving circumstances, the cooperation between data holders is necessary while the privacy of the participators should be guaranteed. In this paper, we focus on privacy preserving LOF. We propose a novel algorithm for privacy preserving k-distance neighbors search. Combining it with other secure multiparty computation techniques, we detect outliers by LOF in a privacy preserving way.",
        "keywords": [
            "novel algorithm",
            "intrusion detection",
            "outlier detection algorithm",
            "multiparty computation techniques",
            "fraud detection",
            "image processing",
            "pattern recognition",
            "data privacy",
            "k-distance neighbors",
            "privacy preserving density-based outlier detection",
            "k-distance neighbor",
            "privacy preserving",
            "important density-based algorithm",
            "density-based algorithm",
            "data holder",
            "data mining",
            "privacy preserving density-based outlier",
            "kdn",
            "outlier detection",
            "lof",
            "critical step",
            "k-distance neighbors search",
            "security of data",
            "algorithm design and analysis",
            "computer science",
            "object recognition",
            "mobile computing",
            "security",
            "secure multiparty computation",
            "quantum computing",
            "high performance computing",
            "privacy",
            "mobile communication"
        ],
        "authors": [
            {
                "name": "Zaisheng Dai",
                "org": ""
            },
            {
                "name": "Liusheng Huang",
                "org": ""
            },
            {
                "name": "Youwen Zhu",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            }
        ],
        "venue": "CMC), 2010 International Conference",
        "year": 2010
    },
    "0mGwetbN": {
        "id": "0mGwetbN",
        "title": "Relation of PPAtMP and scalar product protocol and their applications",
        "abstract": "Scalar product protocol and privacy preserving add to multiply protocol (PPAtMP) are two significant basic secure multiparty computation protocols. In this paper, we claim that the two protocols are equivalent to each other and we can achieve one based on the other with the same communication and computation complexity. Then, we propose Secure Two-party Mean Protocol, Secure Shared x ln x Protocol and Secure Shared Generic Polynomial Protocol based on scalar product protocol and PPAtMP. Additionally, we analyze the correctness, security, communication overheads and computation complexity of each protocol proposed in this paper.",
        "keywords": [
            "scalar product protocol",
            "secure two-party mean protocol",
            "secure shared generic polynomial",
            "communication overhead",
            "computation complexity",
            "basic secure multiparty computation",
            "secure multiparty computation",
            "cryptography",
            "data mining",
            "secure communication",
            "polynomials",
            "data privacy",
            "scalar product",
            "computational complexity",
            "protocols",
            "privacy"
        ],
        "authors": [
            {
                "name": "Youwen Zhu",
                "org": "National High Performance Computing Center at Hefei, Department of Computer Science and Technology, University of Science and Technology of China, 230026, China"
            },
            {
                "name": "Liusheng Huang",
                "org": "National High Performance Computing Center at Hefei, Department of Computer Science and Technology, University of Science and Technology of China, 230026, China"
            },
            {
                "name": "Wei Yang",
                "org": "National High Performance Computing Center at Hefei, Department of Computer Science and Technology, University of Science and Technology of China, 230026, China"
            }
        ],
        "venue": "ISCC",
        "year": 2010
    },
    "ntV6743I": {
        "id": "ntV6743I",
        "title": "Efficient protocols for point-convex hull inclusion decision problems",
        "abstract": "",
        "keywords": [
            "computational geometry",
            "convex hull",
            "point inclusion problem",
            "privacy-preserving",
            "secure multi-party computation",
            "secure protocol",
            "decision problem",
            "secure multi party computation"
        ],
        "authors": [
            {
                "name": "Yun Ye",
                "org": ""
            },
            {
                "name": "Liusheng Huang",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Youwen Zhu",
                "org": ""
            }
        ],
        "venue": "JNW",
        "year": 2010
    },
    "W5tfa0aZ": {
        "id": "W5tfa0aZ",
        "title": "Privacy Preserving Aggregate Query of OLAP for Accurate Answers.",
        "abstract": "In recent years, privacy protection has become an important topic when cooperative computation is performed in distributed environments. This paper puts forward efficient protocols for computing the multi-dimensional aggregates in distributed environments while keeping privacy preserving. We propose a novel model, which contains two crucial stages: local computation and cooperative computation based on secure multiparty computation protocols for privacy-preserving on-line analytical processing. According to the new model, we develop approaches to privacy-preserving count aggregate query over both horizontally partitioned data and vertically partitioned data. We, meanwhile, propose an efficient sub-protocol Two-Round Secure Sum Protocol. Theoretical analysis indicates that our solutions are secure and the answers are exactly accurate, that is, they can securely obtain the exact answer to aggregate query without revealing anything about their confidential data to each other. We also analyze detailedly the communication cost and computation complexity of our schemes in the paper and it shows that the new solutions have good linear complexity. No privacy loss and exact accuracy are two main significant advantages of our new schemes. © 2010 ACADEMY PUBLISHER.",
        "keywords": [
            "homomorphic encryption",
            "olap",
            "privacy",
            "scalar product protocol",
            "secure multiparty computation"
        ],
        "authors": [
            {
                "name": "Youwen Zhu",
                "org": ""
            },
            {
                "name": "Liusheng Huang",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Fan Dong",
                "org": ""
            }
        ],
        "venue": "JCP",
        "year": 2010
    },
    "rPDIbz6n": {
        "id": "rPDIbz6n",
        "title": "A novel multiparty quantum secret sharing scheme of secure direct communication based on bell states and bell measurements",
        "abstract": "We present a novel quantum secret sharing scheme of secure direct communication and analyze its security. This scheme takes Einstein-Podolsky- Rosen (EPR) pairs in Bell states as quantum resources. In order to obtain the direct communication message, all agents only need to perform Bell measurements, not to perform any local unitary operation. The total efficiency in this scheme approaches 100% as the classical information exchanged is unnecessary except for the eavesdropping checks. © 2011 Chinese Physical Society and IOP Publishing Ltd.",
        "keywords": [
            "information exchange",
            "it security"
        ],
        "authors": [
            {
                "name": "RunHua Shi",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Liusheng Huang",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Wei Yang",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Hong Zhong",
                "org": "Anhui University(Anhui University),Hefei,China"
            }
        ],
        "venue": "Chinese Physics Letters",
        "year": 2011
    },
    "xBOS4DF3": {
        "id": "xBOS4DF3",
        "title": "Asymmetric multi-party quantum state sharing of an arbitrary m-qubit state",
        "abstract": "We present a scheme for asymmetric multi-party quantum state sharing of an arbitrary m-qubit state with n agents. The sender Alice first shares m 驴 1 Bell states and one n + 1-particle Greenberger---Horne---Zeilinger state with n agents, where the agent Bob, who is designated to recover the original m-qubit state, just keeps m particles and other agents (all controllers) n 驴 1 particles, that is, each controller only holds one particle in hand. Subsequently, Alice performs m Bell-basis measurements on her 2m particles and each controller only need take a single-particle measurement on his particle with the basis X. Finally, Bob can recover the original m-qubit state with the corresponding local unitary operations according to Alice and all controllers' measurement results. Its intrinsic efficiency for qubits approaches 100%, and the total efficiency really approaches the maximal value, which is higher than those of the known symmetric schemes.",
        "keywords": [
            "original m-qubit state",
            "shares m",
            "sender alice",
            "bell state",
            "m bell-basis measurement",
            "zeilinger state",
            "m particle",
            "n agent",
            "asymmetric multi-party quantum state",
            "arbitrary m-qubit state",
            "quantum cryptography",
            "quantum communication",
            "quantum information",
            "secret sharing"
        ],
        "authors": [
            {
                "name": "Run-Hua Shi",
                "org": "NHPCC, School of Computer Science and Technology, USTC, Hefei, China 230027 and School of Computer Science and Technology, Anhui University, Hefei, China 230039"
            },
            {
                "name": "Liu-Sheng Huang",
                "org": "NHPCC, School of Computer Science and Technology, USTC, Hefei, China 230027 and Suzhou Institute for Advanced Study, USTC, Suzhou, China 215123"
            },
            {
                "name": "Wei Yang",
                "org": "NHPCC, School of Computer Science and Technology, USTC, Hefei, China 230027 and Suzhou Institute for Advanced Study, USTC, Suzhou, China 215123"
            },
            {
                "name": "Hong Zhong",
                "org": "School of Computer Science and Technology, Anhui University, Hefei, China 230039"
            }
        ],
        "venue": "Quantum Information Processing",
        "year": 2011
    },
    "yCWnBxBh": {
        "id": "yCWnBxBh",
        "title": "Detection of substitution-based linguistic steganography by relative frequency analysis",
        "abstract": "Linguistic steganography hides information in natural language texts. Because of the increasing in importance and quantity of natural language texts, linguistic steganography plays a more and more important role in Information Security (IS) area today. Substitution-based linguistic steganography is one of the most commonly used linguistic steganography methods, which is of considerable security and favorable simpleness. In this paper, we propose a straightforward method based on Relative Frequency Analysis (RFA), which makes use of the frequency characteristics of the testing texts (the texts being tested), to detect substitution-based linguistic steganography. We formally prove several properties about relative frequency which can be used in the detection process and propose a detection scheme. And then as an example, an existent synonym-substitution system T-Lex is examined and the detection experiment is carried out. In the experiment with pure literature texts, the accuracy, precision and recall of the detection are found to be as high as 98.64%, 97.77% and 99.55%, respectively, when the substitution count is 90, while in the experiment with balanced texts, the highest detection accuracy is 95%, which indicates that the detection scheme is promising.",
        "keywords": [
            "substitution-based",
            "relative frequency analysis",
            "substitution-based linguistic steganography",
            "synonym-substitution",
            "detection experiment",
            "linguistic steganography hides information",
            "detection process",
            "frequency characteristic",
            "linguistic steganography",
            "natural language text",
            "linguistic steganography method",
            "highest detection accuracy",
            "information hiding",
            "detection",
            "detection scheme",
            "frequency analysis",
            "information security",
            "natural language"
        ],
        "authors": [
            {
                "name": "Zhili Chen",
                "org": "NHPCC, School of CS. & Tech., USTC, Hefei 230027, China and Suzhou Institute for Advanced Study, USTC, Suzhou 215123, China"
            },
            {
                "name": "Liusheng Huang",
                "org": "NHPCC, School of CS. & Tech., USTC, Hefei 230027, China and Suzhou Institute for Advanced Study, USTC, Suzhou 215123, China"
            },
            {
                "name": "Wei Yang",
                "org": "NHPCC, School of CS. & Tech., USTC, Hefei 230027, China and Suzhou Institute for Advanced Study, USTC, Suzhou 215123, China"
            }
        ],
        "venue": "Digital Investigation",
        "year": 2011
    },
    "2ekeIgru": {
        "id": "2ekeIgru",
        "title": "Asymmetric multi-party quantum state sharing of an arbitrary -qubit state",
        "abstract": "We present a scheme for asymmetric multi-party quantum state sharing of an arbitrary m-qubit state with n agents. The sender Alice first shares m − 1 Bell states and one n + 1-particle Greenberger–Horne–Zeilinger state with n agents, where the agent Bob, who is designated to recover the original m-qubit state, just keeps m particles and other agents (all controllers) n − 1 particles, that is, each controller only holds one particle in hand. Subsequently, Alice performs m Bell-basis measurements on her 2m particles and each controller only need take a single-particle measurement on his particle with the basis X. Finally, Bob can recover the original m-qubit state with the corresponding local unitary operations according to Alice and all controllers’ measurement results.\n Its intrinsic efficiency for qubits approaches 100%, and the total efficiency really approaches the maximal value, which is\n higher than those of the known symmetric schemes.",
        "keywords": [
            "Quantum information",
            "Quantum communication",
            "Quantum cryptography",
            "Quantum secret sharing"
        ],
        "authors": [
            {
                "name": "Run-hua Shi",
                "org": "NHPCC, School of Computer Science and Technology,USTC,Hefei,ChinaSchool of Computer Science and Technology,Anhui University,Hefei,China"
            },
            {
                "name": "Liu-sheng Huang",
                "org": "NHPCC, School of Computer Science and Technology,USTC,Hefei,ChinaSuzhou Institute for Advanced Study,USTC,Suzhou,China"
            },
            {
                "name": "Wei Yang",
                "org": "NHPCC, School of Computer Science and Technology,USTC,Hefei,ChinaSuzhou Institute for Advanced Study,USTC,Suzhou,China"
            },
            {
                "name": "Hong Zhong",
                "org": "School of Computer Science and Technology,Anhui University,Hefei,China"
            }
        ],
        "venue": "Quantum Information Processing",
        "year": 2011
    },
    "ruxDxAXd": {
        "id": "ruxDxAXd",
        "title": "Steganalysis against substitution-based linguistic steganography based on context clusters",
        "abstract": "Linguistic steganalysis has been an increasing interest stimulated by the emerging research area of linguistic steganography during the past few years. However, due to limitations of computer natural language processing capability, linguistic steganalysis is a challenging task. Existing steganalysis methods are inefficient to analyze most substitution-based linguistic steganography methods which preserve the syntactic and semantic correctness of cover texts. This paper provides a new steganalysis scheme against substitution-based linguistic steganography based on context clusters. In this scheme, we introduce context clusters to estimate the context fitness and show how to use the statistics of context fitness values to distinguish between normal texts and stego texts. Finally, under this scheme, we present the steganalysis method for synonym substitution-based linguistic steganography. Our experimental results show that the proposed steganalysis method can analyze synonym substitution-based linguistic steganography efficiently and the steganalysis accuracy reaches as high as 98.86%.",
        "keywords": [
            "proposed steganalysis method",
            "new steganalysis scheme",
            "steganalysis method",
            "substitution-based linguistic steganography",
            "linguistic steganography",
            "context cluster",
            "synonym substitution-based linguistic steganography",
            "substitution-based linguistic steganography method",
            "linguistic steganalysis",
            "steganalysis accuracy"
        ],
        "authors": [
            {
                "name": "Zhili Chen",
                "org": "NHPCC, Depart. of CS. & Tech., University of Science and Technology of China, Hefei 230027, China and Suzhou Institute for Advanced Study, USTC, Suzhou 215123, China"
            },
            {
                "name": "Liusheng Huang",
                "org": "NHPCC, Depart. of CS. & Tech., University of Science and Technology of China, Hefei 230027, China and Suzhou Institute for Advanced Study, USTC, Suzhou 215123, China"
            },
            {
                "name": "Haibo Miao",
                "org": "NHPCC, Depart. of CS. & Tech., University of Science and Technology of China, Hefei 230027, China and Suzhou Institute for Advanced Study, USTC, Suzhou 215123, China"
            },
            {
                "name": "Wei Yang",
                "org": "NHPCC, Depart. of CS. & Tech., University of Science and Technology of China, Hefei 230027, China and Suzhou Institute for Advanced Study, USTC, Suzhou 215123, China"
            },
            {
                "name": "Peng Meng",
                "org": "NHPCC, Depart. of CS. & Tech., University of Science and Technology of China, Hefei 230027, China"
            }
        ],
        "venue": "Computers & Electrical Engineering",
        "year": 2011
    },
    "Zo1YURTM": {
        "id": "Zo1YURTM",
        "title": "Efficient Symmetric Five-Party Quantum State Sharing of an Arbitrary m-Qubit State",
        "abstract": "We present an efficient symmetric scheme for five-party quantum state sharing of an arbitrary m-qubit state with 2m three-particle entangled states. The implementations of this scheme only need to exploit the CNOT gate operations and the single-particle measurements, instead of the three-particle GHZ-state measurements, which makes it more convenient in a practical application than some previous schemes. In addition, its total efficiency can approach the maximal value in theory. © 2011 Springer Science+Business Media, LLC.",
        "keywords": [
            "Quantum cryptography",
            "Quantum secret sharing",
            "Quantum state sharing"
        ],
        "authors": [
            {
                "name": "RunHua Shi",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Liusheng Huang",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Wei Yang",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Hong Zhong",
                "org": "Anhui University(Anhui University),Hefei,China"
            }
        ],
        "venue": "International Journal of Theoretical Physics",
        "year": 2011
    },
    "QaZPQaLX": {
        "id": "QaZPQaLX",
        "title": "Blind linguistic steganalysis against translation based steganography",
        "abstract": "Translation based steganography (TBS) is a kind of relatively new and secure linguistic steganography. It takes advantage of the \"noise\" created by automatic translation of natural language text to encode the secret information. Up to date, there is little research on the steganalysis against this kind of linguistic steganography. In this paper, a blind steganalytic method, which is named natural frequency zoned word distribution analysis (NFZ-WDA), is presented. This method has improved on a previously proposed linguistic steganalysis method based on word distribution which is targeted for the detection of linguistic steganography like nicetext and texto. The newmethod aims to detect the application of TBS and uses none of the related information about TBS, its only used resource is a word frequency dictionary obtained from a large corpus, or a so called natural frequency dictionary, so it is totally blind. To verify the effectiveness of NFZ-WDA, two experiments with two-class and multi-class SVM classifiers respectively are carried out. The experimental results show that the steganalytic method is pretty promising.",
        "keywords": [
            "steganalytic method",
            "blind steganalytic method",
            "secure linguistic steganography",
            "word distribution",
            "natural frequency dictionary",
            "natural frequency",
            "linguistic steganography",
            "word frequency dictionary",
            "natural language text",
            "blind linguistic steganalysis",
            "linguistic steganalysis method",
            "word frequency",
            "natural language"
        ],
        "authors": [
            {
                "name": "Zhili Chen",
                "org": "NHPCC, School of CS. & Tech., USTC, Hefei, China and Suzhou Institute for Advanced Study, USTC, Suzhou, China"
            },
            {
                "name": "Liusheng Huang",
                "org": "NHPCC, School of CS. & Tech., USTC, Hefei, China and Suzhou Institute for Advanced Study, USTC, Suzhou, China"
            },
            {
                "name": "Peng Meng",
                "org": "NHPCC, School of CS. & Tech., USTC, Hefei, China"
            },
            {
                "name": "Wei Yang",
                "org": "NHPCC, School of CS. & Tech., USTC, Hefei, China and Suzhou Institute for Advanced Study, USTC, Suzhou, China"
            },
            {
                "name": "Haibo Miao",
                "org": "NHPCC, School of CS. & Tech., USTC, Hefei, China"
            }
        ],
        "venue": "Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)",
        "year": 2011
    },
    "Hz2EM1pq": {
        "id": "Hz2EM1pq",
        "title": "LinL: lost in n-best list",
        "abstract": "Translation-based steganography (TBS) is a new kind of text steganographic scheme. However, contemporary TBS methods are vulnerable to statistical attacks. Differently, this paper presents a novel TBS, namely Lost in n-best List, abbreviated as LinL, that is resilient against the current statistical attacks. LinL employs only one Statistical Machine Translator (SMT) in the encoding process which selects one of the n-best list of each cover text sentence in order to camouflage messages in stegotext. The presented theoretical analysis demonstrates that there is a classification accuracy upper bound between normal translated text and the stegotext. When the text size is 1000 sentences, the theoretical maximum classification accuracy is about 60%. The experiment results also show current steganalysis methods cannot detect LinL.",
        "keywords": [
            "contemporary tbs method",
            "n-best list",
            "cover text sentence",
            "current steganalysis method",
            "classification accuracy",
            "current statistical attack",
            "text size",
            "novel tbs",
            "statistical attack",
            "text steganographic scheme"
        ],
        "authors": [
            {
                "name": "Peng Meng",
                "org": "NHPCC, Depart. of CS. & Tech., USTC, Hefei, China and New Jersey Institute of Technology, Newark, New Jersey"
            },
            {
                "name": "Yun-Qing Shi",
                "org": "New Jersey Institute of Technology, Newark, New Jersey"
            },
            {
                "name": "Liusheng Huang",
                "org": "NHPCC, Depart. of CS. & Tech., USTC, Hefei, China and Suzhou Institute for Advanced Study, USTC, Suzhou, China"
            },
            {
                "name": "Zhili Chen",
                "org": "NHPCC, Depart. of CS. & Tech., USTC, Hefei, China and Suzhou Institute for Advanced Study, USTC, Suzhou, China"
            },
            {
                "name": "Wei Yang",
                "org": "NHPCC, Depart. of CS. & Tech., USTC, Hefei, China and Suzhou Institute for Advanced Study, USTC, Suzhou, China"
            },
            {
                "name": "Abdelrahman Desoky",
                "org": "CSEE, University of Maryland, Baltimore County, MD"
            }
        ],
        "venue": "Information Hiding",
        "year": 2011
    },
    "Pb9HriD4": {
        "id": "Pb9HriD4",
        "title": "An improved AES S-box and its performance analysis",
        "abstract": "S-box is a unique nonlinear operation in Rijndael, one encryption algorithm chosen as AES, and it determines the performance of AES. In this paper, the weaknesses in complexity and security of AES S-box are analyzed. We propose to increase the complexity and security of AES S-box by modifying the affine transformation and dding an affine transformation. Performance analysis demonstrates that the improved AES S-box has following cryptographic properties: the affine transformation period is increased from 4 to the most 16, the iterative period is increased from less than 88 to the most 256, and the distance to SAC is reduced from 432 to 372. Moreover, the number of terms in the improved AES S-box algebraic expression is increased from 9 to 255, and its inverse S-box keeps almost the same as AES inverse S-box. Comparison results suggest that the improved AES S-box has better performance and can readily be applied to AES. © 2011 ICIC INTERNATIONAL.",
        "keywords": [
            "AES",
            "Affine transformation",
            "Inverse S-box",
            "Rijndael"
        ],
        "authors": [
            {
                "name": "Jie Cui",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Liusheng Huang",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Hong Zhong",
                "org": "Anhui University(Anhui University),Hefei,China"
            },
            {
                "name": "Chinchen Chang",
                "org": "Feng Chia University(Feng Chia University,Feng Chia Univ,Feng-Chia University),Taichung,Taiwan"
            },
            {
                "name": "Wei Yang",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            }
        ],
        "venue": "International Journal of Innovative Computing, Information and Control",
        "year": 2011
    },
    "Q7rL2l4v": {
        "id": "Q7rL2l4v",
        "title": "Dynamic trust evaluation model under distributed computing environment",
        "abstract": "With the development of computer networks, distributed computing technology has been far and wide used and it makes that trust evaluation is more and more significant for computing nodes. Referring to the people's trust relationship model of Sociology and considering the dynamic, continuity and uncertainty of trust under the network environment, this paper proposes a dynamic trust evaluation model under distributed computing environment, based on the Dempster-Shafer Theory and Shapley entropy. The trust evaluation is partitioned into two stages: direct trust evaluation stage and integrative trust evaluation stage. The trust evaluation model uses historical interactive information to compute the direct trust. Shapley entropy evaluates the quantity of information of each node's direct trust function, and then the direct trust is revised in consideration of each node's reliability and its quantity of information. Afterwards, they compute the integrative trust derived from the revised direct trust of all nodes according to the Dempster rules. Additionally, the dynamic trust evaluation model is analyzed by simulation experiment and present the plans for future work.",
        "keywords": [
            "Belief measure",
            "Dempster-Shafer evidence theory",
            "Distributed computing environment",
            "Dynamic trust evaluation model",
            "Shapley entropy"
        ],
        "authors": [
            {
                "name": "ZHU You-Wen",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "HUANG Liu-Sheng",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "CHEN Guo-Liang",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Wei Yang",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            }
        ],
        "venue": "Jisuanji Xuebao/Chinese Journal of Computers",
        "year": 2011
    },
    "Lss7zsC8": {
        "id": "Lss7zsC8",
        "title": "Dynamic Trust Evaluation Model Under Distributed Computing Environment: Dynamic Trust Evaluation Model Under Distributed Computing Environment",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "wei yang",
                "org": ""
            },
            {
                "name": "guoliang chen",
                "org": ""
            },
            {
                "name": "liusheng huang",
                "org": ""
            },
            {
                "name": "youwen zhu",
                "org": ""
            }
        ],
        "venue": "Chinese Journal of Computers",
        "year": 2011
    },
    "L0QORSdV": {
        "id": "L0QORSdV",
        "title": "Controlled quantum perfect teleportation of multiple arbitrary multi-qubit states",
        "abstract": "We present an efficient controlled quantum perfect teleportation scheme. In our scheme, multiple senders can teleport multiple arbitrary unknown multi-qubit states to a single receiver via a previously shared entanglement state with the help of one or more controllers. Furthermore, our scheme has a very good performance in the measurement and operation complexity, since it only needs to perform Bell state and single-particle measurements and to apply Controlled-Not gate and other single-particle unitary operations. In addition, compared with traditional schemes, our scheme needs less qubits as the quantum resources and exchanges less classical information, and thus obtains higher communication efficiency.",
        "keywords": [
            "quantum state sharing",
            "controlled quantum teleportation",
            "perfect quantum teleportation"
        ],
        "authors": [
            {
                "name": "RunHua Shi",
                "org": "National High Performance Computing Center at Hefei, Department of Computer Science and Technology, University of Science and Technology of China, Hefei, 230027, China ; School of Computer Science and Technology, Anhui University, Hefei, 230039, China"
            },
            {
                "name": "LiuSheng Huang",
                "org": "National High Performance Computing Center at Hefei, Department of Computer Science and Technology, University of Science and Technology of China, Hefei, 230027, China ; Suzhou Institute for Advanced Study, USTC, Suzhou, 215123, China"
            },
            {
                "name": "Wei Yang",
                "org": "National High Performance Computing Center at Hefei, Department of Computer Science and Technology, University of Science and Technology of China, Hefei, 230027, China ; Suzhou Institute for Advanced Study, USTC, Suzhou, 215123, China"
            },
            {
                "name": "Hong Zhong",
                "org": "School of Computer Science and Technology, Anhui University, Hefei, 230039, China"
            }
        ],
        "venue": "中国科学:物理学 力学 天文学(英文版)",
        "year": 2011
    },
    "1uoXYGNP": {
        "id": "1uoXYGNP",
        "title": "Cryptanalysis and Improvement of a Certificateless Multi-proxy Signature Scheme",
        "abstract": "Certificateless cryptography is a new type of public key cryptography, which removes the certificate management problem in traditional public key cryptography and the key escrow problem in identity-based public key cryptography. Multi-proxy signature is an extension of proxy signature, which allows an original signer authorizing a group of proxy signers and only the cooperation of all proxy signers in the group can create valid proxy signatures on behalf of the original signer. Recently, Jin and Wen combined certificateless cryptography with multi-proxy signature, and proposed a model as well as a concrete scheme of certificateless multi-proxy signature. They claimed that their scheme is provably secure in their security model. Unfortunately, in this paper by giving two attacks, we will show that their certificateless multi-proxy signature scheme can be broken. The first attack indicates their security model is flawed and the second attack indicates their certificateless multi-proxy signature scheme is insecure. Possible improvements are also suggested to prevent these attacks.",
        "keywords": [
            "identity-based public key cryptography",
            "certificateless multi-proxy signature scheme",
            "certificateless cryptography",
            "proxy signer",
            "multi-proxy signature",
            "proxy signature",
            "security model",
            "valid proxy signature",
            "certificateless multi-proxy signature",
            "original signer",
            "cryptanalysis"
        ],
        "authors": [
            {
                "name": "Miaomiao Tian",
                "org": "School of Computer Science and Technology, University of Science and Technology of China, Hefei 230026, P.R. China. miaotian@mail.ustc.edu.cn"
            },
            {
                "name": "Wei Yang",
                "org": "School of Computer Science and Technology, University of Science and Technology of China, Hefei 230026, P.R. China. miaotian@mail.ustc.edu.cn"
            },
            {
                "name": "Liusheng Huang",
                "org": "School of Computer Science and Technology, University of Science and Technology of China, Hefei 230026, P.R. China. miaotian@mail.ustc.edu.cn"
            }
        ],
        "venue": "Fundam. Inform.",
        "year": 2011
    },
    "iU1iEZwl": {
        "id": "iU1iEZwl",
        "title": "Multi-party quantum state sharing of an arbitrary two-qubit state with Bell states",
        "abstract": "We present a new scheme for sharing an arbitrary two-qubit quantum state with n agents. In our scheme, the sender Alice first shares n Einsein-Podolsky-Rosen (EPR) pairs in Bell states with n agents. After setting up the secure quantum channel, Alice first applies (n 驴 2) Controlled-Not (CNOT) gate operations, and then performs two Bell-state measurements and (n 驴 2) single-particle measurements (n 2). In addition, all controllers only hold one particle in their hands, respectively, and thus they only need to perform a single-particle measurement on the respective particle with the basis $${\\{{\\vert}0\\rangle, {\\vert}1\\rangle\\}}$$ . Compared with other schemes with Bell states, our scheme needs less qubits as the quantum resources and exchanges less classical information, and thus obtains higher total efficiency.",
        "keywords": [
            "Quantum information",
            "Quantum cryptography",
            "Quantum secret sharing",
            "Quantum state sharing"
        ],
        "authors": [
            {
                "name": "Run-Hua Shi",
                "org": "NHPCC, Depart. of CS. & Tech., USTC, Hefei, China 230027 and School of Computer Science and Technology, Anhui University, Hefei, China 230039"
            },
            {
                "name": "Liu-Sheng Huang",
                "org": "NHPCC, Depart. of CS. & Tech., USTC, Hefei, China 230027 and Suzhou Institute for Advanced Study, USTC, Suzhou, China 215123"
            },
            {
                "name": "Wei Yang",
                "org": "NHPCC, Depart. of CS. & Tech., USTC, Hefei, China 230027 and Suzhou Institute for Advanced Study, USTC, Suzhou, China 215123"
            },
            {
                "name": "Hong Zhong",
                "org": "School of Computer Science and Technology, Anhui University, Hefei, China 230039"
            }
        ],
        "venue": "Quantum Information Processing",
        "year": 2011
    },
    "9R1azlmy": {
        "id": "9R1azlmy",
        "title": "On the security of a certificateless short signature scheme.",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Miaomiao Tian",
                "org": ""
            },
            {
                "name": "Liusheng Huang",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            }
        ],
        "venue": "IACR Cryptology ePrint Archive",
        "year": 2011
    },
    "Q6tyZ5Ul": {
        "id": "Q6tyZ5Ul",
        "title": "Efficient collusion-resisting secure sum protocol",
        "abstract": "Secure sum protocol is a significant secure multiparty computation protocol and it has various applications in privacy-preserving distributed multiparty computation. However, most existing secure sum protocols rarely considered how to resist underlying collusion which is a significant practical problem. Urabe et al. proposed a collusion-resistant secure sum protocol, but too much cost of communication and computation results in its low performance efficiency. In this paper, we propose security definitions to measure secure multiparty computation protocol's capability of resisting potential collusion. Then, we precisely analyze several previous secure sum protocols' capability of resisting collusion. In addition, considering realistic requirement to resist collusion and performance efficiency needs, we present a novel collusion-resisting secure sum protocol. Theoretical analysis and experimental results confirm that our secure sum protocol is efficient and has strong capability of resisting potential collusion such that it is much superior to previous ones. The communication overheads and computation complexity of our scheme both are linearity of the number of participants. Besides, our protocol's capability of resisting collusion is adjustable according to different security needs.",
        "keywords": [
            "Collusion",
            "Privacy-preserving",
            "Secure multiparty computation",
            "Secure sum"
        ],
        "authors": [
            {
                "name": "Youwen Zhu",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Liusheng Huang",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Wei Yang",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Xing Yuan",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            }
        ],
        "venue": "Chinese Journal of Electronics",
        "year": 2011
    },
    "DEZgjRgp": {
        "id": "DEZgjRgp",
        "title": "Infeasibility of quantum cryptography without eavesdropping check",
        "abstract": "Secure key distribution is impossible in pure classical environment. Unconditional secure key distribution is available when quantum means are introduced, assisted by a classical communication channel. What is possible when a quantum key distribution scheme is without classical communication? We present a general model with this constraint and show that quantum key distribution without classical eavesdropping check is in principle impossible. For an adversary can always succeed in obtaining the secret key via a special case of man-in-the-middle attack, namely intercept-and-forward attack without any risk of being captured. © 2011 World Scientific Publishing Company.",
        "keywords": [
            "classical communication",
            "intercept-and-forward attack",
            "key distribution",
            "quantum cryptography",
            "man in the middle attack",
            "communication channels",
            "quantum key distribution"
        ],
        "authors": [
            {
                "name": "Wei Yang",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Liusheng Huang",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Fang Song",
                "org": "Pennsylvania State University(Pennsylvania State University,The Pennsylvania State University,Pennsylvania State Univ),State College,United States"
            },
            {
                "name": "Qiyan Wang",
                "org": "University of Illinois at Urbana-Champaign(University of Illinois at Urbana-Champaign,Univ. Illinois at Urbana-Champaign,University of Illinois,Univ of Illinois at Urbana-Champaign),Urbana,United States"
            }
        ],
        "venue": "International Journal of Modern Physics B",
        "year": 2011
    },
    "NQlQsWgA": {
        "id": "NQlQsWgA",
        "title": "Quantum group blind signature scheme without entanglement",
        "abstract": "In this paper we propose a quantum group blind signature scheme designed for distributed e-voting system. Our scheme combines the properties of group signature and blind signature to provide anonymity of voters in an e-voting system. The unconditional security of our scheme is ensured by quantum mechanics. Without employing entanglement, the proposed scheme is easier to be realized comparing with other quantum signature schemes.",
        "keywords": [
            "group signature",
            "blind signature",
            "quantum signature",
            "quantum group",
            "quantum mechanics"
        ],
        "authors": [
            {
                "name": "Rui Xu",
                "org": ""
            },
            {
                "name": "Liusheng Huang",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Libao He",
                "org": ""
            }
        ],
        "venue": "Optics Communications",
        "year": 2011
    },
    "SLQKCeDN": {
        "id": "SLQKCeDN",
        "title": "Privacy-preserving Text Information Hiding Detecting Algorithm",
        "abstract": "Text information hiding detecting algorithm aims at distinguishing between normal text and sgeto-text.How to perform securely collaborative text information detection remains unsettled.For this reason,a privacy-preserving text information hiding detecting algorithm is proposed based on homomorphic cryptosystem.The new detecting algorithm achieves securely two-party collaborative text information detecting,by which the party holding privately parameters of text information hiding detecting algorithm and the party holding a private text to detect can cooperatively distinguish between sgeto-text and normal text while no privacy is disclosed.It is shown the privacy-preserving algorithm is still secure while a couple of parties cooperate for many times.Communication overheads and computation complexity of the privacy-preserving algorithm are where m is the number of words in the dictionary using by text detecting algorithm.Experimental result shows the algorithm is efficient.",
        "keywords": [
            "N-window mutual information",
            "Information hiding",
            "Privacy-preserving",
            "Correlations between words"
        ],
        "authors": [
            {
                "name": "Zhu You-wen",
                "org": "National High Performance Computing Center at Hefei,Department of Computer Science and Technology,University of Science and Technology of China,Hefei ,China)②(Department of Computer Science and Engineering,Ohio State University,Columbus,Ohio,USA)"
            },
            {
                "name": "Huang Liu-sheng",
                "org": "National High Performance Computing Center at Hefei,Department of Computer Science and Technology,University of Science and Technology of China,Hefei ,China)②(Department of Computer Science and Engineering,Ohio State University,Columbus,Ohio,USA)"
            },
            {
                "name": "Li Dong",
                "org": "National High Performance Computing Center at Hefei,Department of Computer Science and Technology,University of Science and Technology of China,Hefei ,China)②(Department of Computer Science and Engineering,Ohio State University,Columbus,Ohio,USA)"
            },
            {
                "name": "Yang Wei",
                "org": "National High Performance Computing Center at Hefei,Department of Computer Science and Technology,University of Science and Technology of China,Hefei ,China)②(Department of Computer Science and Engineering,Ohio State University,Columbus,Ohio,USA)"
            }
        ],
        "venue": "Journal of Electronics & Information Technology",
        "year": 2011
    },
    "viW26CLW": {
        "id": "viW26CLW",
        "title": "Privacy-preserving Text Information Hiding Detecting Algorithm: Privacy-preserving Text Information Hiding Detecting Algorithm",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "youwen zhu",
                "org": ""
            },
            {
                "name": "liusheng huang",
                "org": ""
            },
            {
                "name": "dong li",
                "org": ""
            },
            {
                "name": "wei yang",
                "org": ""
            }
        ],
        "venue": "Journal of Electronics Information & Technology",
        "year": 2011
    },
    "kJHOhLbb": {
        "id": "kJHOhLbb",
        "title": "More than Word Frequencies: Authorship Attribution via Natural Frequency Zoned Word Distribution Analysis",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Zhili Chen",
                "org": ""
            },
            {
                "name": "Liusheng Huang",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Peng Meng",
                "org": ""
            },
            {
                "name": "Haibo Miao",
                "org": ""
            }
        ],
        "venue": "CoRR",
        "year": 2012
    },
    "cBum9IzS": {
        "id": "cBum9IzS",
        "title": "A new scheme for covert communication via 3G encoded speech",
        "abstract": "Mobile communication through 3G network has grown rapidly in recent years. It might be of interest to transmit secret messages over 3G voice channels. In this paper, we introduce a new covert communication scheme via Adaptive Multi-Rate Wideband (AMR-WB) encoded speech. An adaptive suboptimal pulse combination constrained (ASOPCC) method is presented to embed data on compressed speech signal of AMR-WB codec. The method takes advantage of the ''redundancy'', created by non-exhaustive search of algebraic codebook, to encode secret information. An embedding factor @h is used to control embedding bits. By properly setting @h, ASOPCC can offer a better trade-off between speech quality and embedding capacity in the process of coding mode switching. Experimental results show that the proposed method is quite promising for both high capacity and good imperceptivity. Although ASOPCC is only applied to AMR-WB codec in this article, it can be further used by any other speech coding based on Algebraic Coded Exited Linear Prediction (ACELP).",
        "keywords": [
            "encoded speech",
            "amr-wb codec",
            "speech signal",
            "coding mode switching",
            "embedding bit",
            "embedding capacity",
            "new scheme",
            "covert communication",
            "embedding factor",
            "speech quality",
            "high capacity"
        ],
        "authors": [
            {
                "name": "Haibo Miao",
                "org": "Department of Computer Science and Technology, University of Science and Technology of China, Hefei 230026, China and Suzhou Institute for Advanced Study, University of Science and Technology of C ..."
            },
            {
                "name": "Liusheng Huang",
                "org": "Department of Computer Science and Technology, University of Science and Technology of China, Hefei 230026, China and Suzhou Institute for Advanced Study, University of Science and Technology of C ..."
            },
            {
                "name": "Zhili Chen",
                "org": "Department of Computer Science and Technology, University of Science and Technology of China, Hefei 230026, China and Suzhou Institute for Advanced Study, University of Science and Technology of C ..."
            },
            {
                "name": "Wei Yang",
                "org": "Department of Computer Science and Technology, University of Science and Technology of China, Hefei 230026, China and Suzhou Institute for Advanced Study, University of Science and Technology of C ..."
            },
            {
                "name": "Ammar Al-Hawbani",
                "org": "Department of Computer Science and Technology, University of Science and Technology of China, Hefei 230026, China"
            }
        ],
        "venue": "Computers & Electrical Engineering",
        "year": 2012
    },
    "MXxaeuC7": {
        "id": "MXxaeuC7",
        "title": "On the security of an enhanced short signature scheme",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Miaomiao Tian",
                "org": ""
            },
            {
                "name": "Liusheng Huang",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            }
        ],
        "venue": "arXiv: Cryptography and Security",
        "year": 2012
    },
    "zEIcC65K": {
        "id": "zEIcC65K",
        "title": "A New Hierarchical Identity-based Signature Scheme From Lattices In The Standard Model.",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Miaomiao Tian",
                "org": ""
            },
            {
                "name": "Liusheng Huang",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            }
        ],
        "venue": "I. J. Network Security",
        "year": 2012
    },
    "KZcoYIRL": {
        "id": "KZcoYIRL",
        "title": "Efficient Lattice-Based Ring Signature Scheme: Efficient Lattice-Based Ring Signature Scheme",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "wei yang",
                "org": ""
            },
            {
                "name": "liusheng huang",
                "org": ""
            },
            {
                "name": "miaomiao tian",
                "org": ""
            }
        ],
        "venue": "Chinese Journal of Computers",
        "year": 2012
    },
    "mAepNWym": {
        "id": "mAepNWym",
        "title": "Security of a biometric identity-based encryption scheme",
        "abstract": "",
        "keywords": [
            "chosen ciphertext attack",
            "random oracle model"
        ],
        "authors": [
            {
                "name": "Miaomiao Tian",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Liusheng Huang",
                "org": ""
            }
        ],
        "venue": "I. J. Network Security",
        "year": 2012
    },
    "4qQYPrRA": {
        "id": "4qQYPrRA",
        "title": "Efficient Lattice-Based Ring Signature Scheme",
        "abstract": "An efficient and secure ring signature scheme has a number of important applications.In this paper,we present a new lattice-based ring signature scheme and prove its security in the standard model.The proposed scheme is strongly unforgeable against adaptive chosen message attacks under the standard small integer solution(SIS) assumption.Compared with the existing lattice-based ring signature schemes without random oracles,our new scheme enjoys shorter signature length,high efficiency and stronger security.",
        "keywords": [
            "lattices",
            "ring signature",
            "efficient",
            "strongly unforgeable",
            "standard model"
        ],
        "authors": [
            {
                "name": "TIAN Miao-Miao",
                "org": ""
            },
            {
                "name": "HUANG Liu-Sheng",
                "org": ""
            },
            {
                "name": "YANG Wei",
                "org": ""
            }
        ],
        "venue": "Chinese Journal of Computers",
        "year": 2012
    },
    "FXu8sR1n": {
        "id": "FXu8sR1n",
        "title": "On the Security of an identity-based short signature scheme",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Miaomiao Tian",
                "org": ""
            },
            {
                "name": "Liusheng Huang",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            }
        ],
        "venue": "CoRR",
        "year": 2012
    },
    "Ygaq3hop": {
        "id": "Ygaq3hop",
        "title": "Security of a Biometric Identity-based Encryption Scheme",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Miaomiao Tian",
                "org": "Univ of Science and Technology of China"
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Liusheng Huang",
                "org": ""
            }
        ],
        "venue": "International Journal of Network Security",
        "year": 2012
    },
    "6SIRYaJH": {
        "id": "6SIRYaJH",
        "title": "A 3G Speech Data Hiding Method Based on Pitch Period",
        "abstract": "Now,mobile communication network has attained thired generation,with the 3G network technology mature and scale unceasing expansion,it is terribly essential to study the 3G covert channel.The research of covert channel based on change coding parameter is a hot spot during the encoding process of the speech.Pitch period is an important parameter to descrip the characteristic of audio.It is diffcult to detect the modification of pitch period,in the process of searching adaptive codebook,new methods of hiding data in the pitch period data of the Adaptive Multi-Rate(AMR) speech codec are proposed,we can embedded information into the content of speech by the algorithm during a voice conversation,this method prevent steganalysis of speech compressed based on voicing features.The simulation result show that this method has good performance of hidden information transmission.",
        "keywords": [
            "data hiding",
            "3G network",
            "AMR-WB speech codec",
            "pitch period"
        ],
        "authors": [
            {
                "name": "YU Chi",
                "org": "National High Performance Computing Center,Department of Computer Science and Technology,University of Science and Technology of China,Hefei ,China;Suzhou Institute for Advanced Study,University of Science and Technology of China,Suzhou ,China"
            },
            {
                "name": "HUANG Liu-sheng",
                "org": "National High Performance Computing Center,Department of Computer Science and Technology,University of Science and Technology of China,Hefei ,China;Suzhou Institute for Advanced Study,University of Science and Technology of China,Suzhou ,China"
            },
            {
                "name": "YANG Wei",
                "org": "National High Performance Computing Center,Department of Computer Science and Technology,University of Science and Technology of China,Hefei ,China;Suzhou Institute for Advanced Study,University of Science and Technology of China,Suzhou ,China"
            },
            {
                "name": "CHEN Zhi-li",
                "org": "National High Performance Computing Center,Department of Computer Science and Technology,University of Science and Technology of China,Hefei ,China;Suzhou Institute for Advanced Study,University of Science and Technology of China,Suzhou ,China"
            },
            {
                "name": "MIAO Hai-bo",
                "org": "National High Performance Computing Center,Department of Computer Science and Technology,University of Science and Technology of China,Hefei ,China;Suzhou Institute for Advanced Study,University of Science and Technology of China,Suzhou ,China"
            }
        ],
        "venue": "Journal of Chinese Computer Systems",
        "year": 2012
    },
    "KtmS1u7K": {
        "id": "KtmS1u7K",
        "title": "Cryptanalysis of fair quantum blind signatures",
        "abstract": "We investigate the fair quantum blind signature scheme proposed by Wang and Wen [Wang T Y and Wen Q Y 2010 Chin.Phys.B 19 060307],which uses the fundamental properties of quantum mechanics and the availability of a trusted arbitrator.However,in this paper,we find that the protocol cannot satisfy the property of non-forgeability even under the condition that the trusted arbitrator is totally credible.Moreover,a simple feasible suggestion for improving the protocol is proposed.",
        "keywords": [],
        "authors": [
            {
                "name": "LiBao He",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Liusheng Huang",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Yang Wei",
                "org": " Suzhou Institute for Advanced Study,University of Science and Technology of China,Suzhou ,China"
            },
            {
                "name": "Rui Xu",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            }
        ],
        "venue": "中国物理B",
        "year": 2012
    },
    "NwdxcBUQ": {
        "id": "NwdxcBUQ",
        "title": "Cryptanalysis of an ID-based proxy signature scheme with message recovery",
        "abstract": "ID-based message recovery signature is a kind of lightweight signature. In such a signature scheme, a complicated certification system is discarded and the total length of the message and the appended signature is also shortened. Proxy signature allows an original signer to delegate a proxy signer to sign messages on its behalf, which has found numerous practical applications such as grid computing and mobile agent systems. Recently, Singh and Verma proposed the first ID-based proxy signature scheme with message recovery. They proved that their scheme is secure in the random oracle model and believed that it can be used widely. Unfortunately, by giving two concrete attacks, we demonstrate that their ID-based message recovery proxy signature scheme is not secure. The result implies that the security for ID-based message recovery proxy signature schemes needs to be carefully examined. © 2012 NSP Natural Sciences Publishing Cor.",
        "keywords": [
            "Cryptanalysis",
            "ID-based cryptography",
            "Message recovery",
            "Proxy signature"
        ],
        "authors": [
            {
                "name": "Miaomiao Tian",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Liusheng Huang",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Wei Yang",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            }
        ],
        "venue": "Applied Mathematics and Information Sciences",
        "year": 2012
    },
    "6BswFrwQ": {
        "id": "6BswFrwQ",
        "title": "A protocol for the secure two-party quantum scalar product",
        "abstract": "",
        "keywords": [
            "quantum cryptography",
            "secure multi party computation",
            "quantum entanglement"
        ],
        "authors": [
            {
                "name": "libao he",
                "org": ""
            },
            {
                "name": "liusheng huang",
                "org": ""
            },
            {
                "name": "wei yang",
                "org": ""
            },
            {
                "name": "rui xu",
                "org": ""
            }
        ],
        "venue": "Physics Letters A",
        "year": 2012
    },
    "MEsfn52F": {
        "id": "MEsfn52F",
        "title": "Novel and effective secret sharing scheme",
        "abstract": "A novel secret sharing scheme was proposed.This scheme consisted of two layer protocols: in the first layer,a larger secret was split into t smaller integers(sub-secrets) based on the Stern-Brocot tree;in the lower layer,t sub-secrets obtained from the first layer were regarded as t initial states in one-dimensional cellular automaton model,and then from the t initial states it could dynamic create all participants' shares according to the simple fixed rule.This scheme could dynamic add new member,adjust the threshold value and renew the secret and the shares.Besides,there were still other advantages that the costs of the computation were very low and the size of the shares was very small.The results of analysis show that it was secure and very efficient.",
        "keywords": [
            "dynamic",
            "secret sharing",
            "Stern-Brocot tree",
            "threshold"
        ],
        "authors": [
            {
                "name": "SHI Run-hua",
                "org": "School of Computer Science and Technology,Anhui University,Hefei ,China;NHPCC,Depart.of CS.& Tech.,USTC,Hefei ,China"
            },
            {
                "name": "HUANG Liu-sheng",
                "org": "NHPCC,Depart.of CS.& Tech.,USTC,Hefei ,China;Suzhou Institute for Advanced Study,USTC,Suzhou ,China"
            },
            {
                "name": "YANG Wei",
                "org": "NHPCC,Depart.of CS.& Tech.,USTC,Hefei ,China;Suzhou Institute for Advanced Study,USTC,Suzhou ,China"
            },
            {
                "name": "ZHONG Hong",
                "org": "School of Computer Science and Technology,Anhui University,Hefei ,China"
            }
        ],
        "venue": "Journal on Communications",
        "year": 2012
    },
    "Pa1SXwnh": {
        "id": "Pa1SXwnh",
        "title": "Cryptanalysis and melioration of secure quantum sealed-bid auction with post-confirmation",
        "abstract": "We investigate the quantum sealed-bid auction protocol proposed by Zhao et al. (Opt Commun 283:1394, 2010). It uses M groups n-particle GHZ states to represent bids and a post-confirmation mechanism to guarantee the honesty of the quantum sealed-bid auction. However, in our opinion the protocol still does not complete the task of a sealed-bid auction fairly. It is shown that a large group of dishonest bidders can collude to obtain all the other one's secret bids before the opening phase of the auction with a probability polynomially close to one. Moreover, a simple feasible improvement of the protocol is proposed.",
        "keywords": [
            "Quantum communication",
            "GHZ states",
            "Quantum sealed-bid auction"
        ],
        "authors": [
            {
                "name": "Li-Bao He",
                "org": "NHPCC, Department of Computer Science and Technology, USTC, Hefei, China 230027"
            },
            {
                "name": "Liu-Sheng Huang",
                "org": "Suzhou Institute for Advanced Study, USTC, Suzhou, China 215123"
            },
            {
                "name": "Wei Yang",
                "org": "Suzhou Institute for Advanced Study, USTC, Suzhou, China 215123"
            },
            {
                "name": "Rui Xu",
                "org": "Suzhou Institute for Advanced Study, USTC, Suzhou, China 215123"
            },
            {
                "name": "Dian-Qi Han",
                "org": "Suzhou Institute for Advanced Study, USTC, Suzhou, China 215123"
            }
        ],
        "venue": "Quantum Information Processing",
        "year": 2012
    },
    "mf8EswOg": {
        "id": "mf8EswOg",
        "title": "Secret sharing based on quantum Fourier transform",
        "abstract": "Secret sharing plays a fundamental role in both secure multi-party computation and modern cryptography. We present a new quantum secret sharing scheme based on quantum Fourier transform. This scheme enjoys the property that each share of a secret is disguised with true randomness, rather than classical pseudorandomness. Moreover, under the only assumption that a top priority for all participants (secret sharers and recovers) is to obtain the right result, our scheme is able to achieve provable security against a computationally unbounded attacker. © 2013 Springer Science+Business Media New York.",
        "keywords": [
            "Secret sharing",
            "Quantum Fourier transform",
            "Computational indistinguishable",
            "Simulator"
        ],
        "authors": [
            {
                "name": "Wei Yang",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Liusheng Huang",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Runhua Shi",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "LiBao He",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            }
        ],
        "venue": "Quantum Information Processing",
        "year": 2013
    },
    "oVyNCqDx": {
        "id": "oVyNCqDx",
        "title": "A Novel Web Tunnel Detection Method Based on Protocol Behaviors.",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Fei Wang",
                "org": ""
            },
            {
                "name": "Liusheng Huang",
                "org": ""
            },
            {
                "name": "Zhili Chen",
                "org": ""
            },
            {
                "name": "Haibo Miao",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            }
        ],
        "venue": "SecureComm",
        "year": 2013
    },
    "lo4OH2xa": {
        "id": "lo4OH2xa",
        "title": "A novel text steganography by context-based equivalent substitution",
        "abstract": "The text steganography is a prevalent technique for covert communication. We propose a novel linguistic steganography by context-based substitution. We utilize the conditional equivalence between the definite article and demonstrative adjectives ubiquitous in natural texts to embed covert messages. Considering the diverse usage of these words, we adopt a part-of-speech filter, a 3-gram language model, a 2-range context, the minimum matching distance, and the perplexity to evaluate the substitution suitability degree in our steganography and the substitution can only be carried out under certain conditions. The results of the blind test show that the generated stego-text can hardly have syntax errors or unsuitable words, which proves that the steganography is imperceptible.",
        "keywords": [
            "steganography",
            "speech processing",
            "syntax error",
            "part-of-speech filter",
            "demonstrative adjective",
            "2-range context",
            "stego-text generation",
            "substitution suitability degree",
            "text steganography",
            "linguistic steganography",
            "context-based substitution",
            "perplexity",
            "context-based equivalent substitution",
            "minimum matching distance",
            "3-gram language model",
            "natural language processing",
            "text analysis",
            "substitution",
            "definite article"
        ],
        "authors": [
            {
                "name": "Fei Wang",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Liusheng Huang",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Zhili Chen",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Wei Yang",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Haibo Miao",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            }
        ],
        "venue": "Signal Processing, Communication and Computing",
        "year": 2013
    },
    "tZYrKQLc": {
        "id": "tZYrKQLc",
        "title": "Steganography in HTML based on substitution of script codes",
        "abstract": "The HTML document is a main kind of public resources in the Internet, while the research in the steganography and steganalysis of them are in the infancy. In this paper, we propose a novel steganography in HTML documents. Different from natural language text, HTML documents have plentiful script codes which can be utilized for covert transmission more easily than the common text. The syntax structures of programming languages are strict and precise, so to generate scripts that are different in text but strictly equivalent in lexeme is possible. In the steganography, based on the substitution of variables and function naming, covert bits are successfully embedded with no script errors. Because of the transparency and flexibility of script codes, the well-disguised stego-HTML document has a legitimate appearance that is imperceptible. In the experiment, the embedding efficiency of the technique is considerable, proving that the steganography is feasible and promising.",
        "keywords": [
            "HTML document",
            "Script",
            "Steganography",
            "Substitution",
            "Text"
        ],
        "authors": [
            {
                "name": "Fei Wang",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Liusheng Huang",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Haibo Miao",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Zhili Chen",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Wei Yang",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            }
        ],
        "venue": "International Journal of Security and its Applications",
        "year": 2013
    },
    "7yVwmknB": {
        "id": "7yVwmknB",
        "title": "Efficient hierarchical identity-based signatures from lattices",
        "abstract": "Lattice-based hierarchical identity-based signature HIBS schemes are receiving significant attention due to provable security reductions and potential security for quantum computers. However, most of the existing HIBS schemes based on lattices are less efficient for practical applications. To make lattice-based HIBS schemes become more practical, this paper presents an efficient HIBS scheme from lattices. Both the secret key size and the signature length of our proposal are much shorter than those of other lattice-based HIBS proposals. Our scheme is proven to be strongly unforgeable against adaptive identity attacks in the random oracle model. The security of the construction relies on the standard short integer solution SIS assumption.",
        "keywords": [],
        "authors": [
            {
                "name": "Miaomiao Tian",
                "org": "School of Computer Science and Technology, University of Science and Technology of China, Hefei 230026, China"
            },
            {
                "name": "Liusheng Huang",
                "org": "School of Computer Science and Technology, University of Science and Technology of China, Hefei 230026, China"
            },
            {
                "name": "Wei Yang",
                "org": "School of Computer Science and Technology, University of Science and Technology of China, Hefei 230026, China"
            }
        ],
        "venue": "IJESDF",
        "year": 2013
    },
    "uQ4F8ppr": {
        "id": "uQ4F8ppr",
        "title": "Quantum-classical hybrid quantum superdense coding",
        "abstract": "Quantum superdense coding (QSC) is an interesting application of quantum communications. It exploits the special property of quantum entanglement to perform classical communications and results in a spectacular result. In this paper, the density of QSC problem is investigated and a time synchronization mechanism is shown to be helpful for improving the coding efficiency. A new quantum-classical hybrid QSC scheme based on a time synchronization mechanism is proposed. The scheme is extended to the case in which any number of qubits (and further qudits) are involved. A desirable coding efficiency, which is shown to converge to log2(d + 1) (where d denotes the dimension of the quantum system employed) in the generalized case, is deduced for this time-assisted superdense coding. © 2013 The Royal Swedish Academy of Sciences.",
        "keywords": [],
        "authors": [
            {
                "name": "Wei Yang",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Liusheng Huang",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "An Liu",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Miaomiao Tian",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Haibo Miao",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            }
        ],
        "venue": "Physica Scripta",
        "year": 2013
    },
    "bRWDFbWd": {
        "id": "bRWDFbWd",
        "title": "Algebraic Attack on Rijndael-192 Based on Grobner Basis",
        "abstract": "Because a key step of Grobner basis attack on Rijndael is constructing its zero-dimensional Grobner basis,authors perform some particular studies on the linear transformation and the system of multivariate polynomial equations of Rijndael-192,and propose its zero-dimensional Grobner basis construction method through choosing suitable term order and variable order.After presenting the construction method of the Grobner basis,authors give the necessary theorical proves.Moreover,authors propose an algebraic attack on Rijndael-192 based on Grobner basis.Analysis suggest that the attack complexity is lower than exhaustive attack.",
        "keywords": [
            "Algebraic attack",
            "Grobner basis",
            "Rijndael algorithm",
            "Multivariate equation system"
        ],
        "authors": [
            {
                "name": "CUI Jie",
                "org": "School of Computer Science and Technology,University of Scienc and Technology of China,Hefei,Anhui ,China;School of Computer Science and Technology,Anhui University,Hefei,Anhui ,China"
            },
            {
                "name": "HUANG Liu-sheng",
                "org": "School of Computer Science and Technology,University of Scienc and Technology of China,Hefei,Anhui ,China;Suzhou Institute for Advanced Study,University of Science and Technology of China,Suzhou,Jiangsu ,China"
            },
            {
                "name": "ZHONG Hong",
                "org": "School of Computer Science and Technology,Anhui University,Hefei,Anhui ,China"
            },
            {
                "name": "YANG Wei",
                "org": "School of Computer Science and Technology,University of Scienc and Technology of China,Hefei,Anhui ,China;Suzhou Institute for Advanced Study,University of Science and Technology of China,Suzhou,Jiangsu ,China"
            }
        ],
        "venue": "Acta Electronica Sinica",
        "year": 2013
    },
    "YRh9nVQ6": {
        "id": "YRh9nVQ6",
        "title": "Secret Confusion of Privacy-preserving Data Aggregation in Wireless Sensor Networks",
        "abstract": "In the field of wireless sensor networks,PDA(Privacy-preserving Data Aggregation) is a hot issue.The design of effective PDA algorithm,w hich aims at saving communication bandw idth and improving the longevity and security of the netw orks at the same time,is the crux of research in data aggregation.According to bibliography of PDA algorithms at home and abroad,most of the designs(excluding PEQ,a Privacy-preserving Scheme for Exact Query Evaluation) are based on the difference of statistical data types,w hich has a draw back that those algorithms could only aggregate a single type of data,thus limiting their field of application.Moreover,the PEQ algorithm is perplexed by the relatively large overhead of communication bandw idth and computation pow er.In order to solve these problems,a PDA algorithm based on data confusion is proposed.This algorithm achieves the goal of privacy preservation by importing confusion data before the process of data aggregation and cut them out after it.Compared to other algorithms,this one consumes less computation pow er,uses less communication bandw idth,and can aggregate several kinds of statistical data at a time.",
        "keywords": [
            "secret confusion",
            "wireless sensor network",
            "privacy-preserving",
            "data aggregation"
        ],
        "authors": [
            {
                "name": "LI Yu-hai",
                "org": "School of Computer Science and Technology,University of Science and Technology of China,Hefei ,China;Suzhou Institute for Advanced Study,University of Science and Technology of China,Suzhou ,China"
            },
            {
                "name": "TIAN Miao-miao",
                "org": "School of Computer Science and Technology,University of Science and Technology of China,Hefei ,China;Suzhou Institute for Advanced Study,University of Science and Technology of China,Suzhou ,China"
            },
            {
                "name": "HUANG Liu-sheng",
                "org": "School of Computer Science and Technology,University of Science and Technology of China,Hefei ,China;Suzhou Institute for Advanced Study,University of Science and Technology of China,Suzhou ,China"
            },
            {
                "name": "YANG Wei",
                "org": "School of Computer Science and Technology,University of Science and Technology of China,Hefei ,China;Suzhou Institute for Advanced Study,University of Science and Technology of China,Suzhou ,China"
            }
        ],
        "venue": "Journal of Chinese Computer Systems",
        "year": 2013
    },
    "O8V5ucr1": {
        "id": "O8V5ucr1",
        "title": "Two novel and secure quantum ANDOS schemes",
        "abstract": "A vendor has several secrets which he regards as of equal worth and importance. He is willing to sell any of these secrets to a buyer. The bargain is said to be secure when the following two conditions are satisfied: 1) the buyer can only obtain one secret if he pays for only one secret, and 2) the vendor will not be able to find out which secret the buyer picked. This cryptographic problem is customarily called all-or-nothing disclosure of secrets (ANDOS). Previous ANDOS schemes have a few defects: neither the number of the secrets is restricted within narrow limits, nor the security is desirable. In this paper, we propose two new and novel ANDOS protocols in quantum computing environment. The first protocol is shown to be as secure as a classical one. The second protocol is based on unambiguous state discrimination, which is proven to be secure in quantum world. Moreover, all our schemes have no limitation on the number of the secrets to be sold. © 2013 NSP Natural Sciences Publishing Cor.",
        "keywords": [
            "Andos",
            "Positive operator valued measure",
            "Qutrit",
            "Unambiguous state discrimination"
        ],
        "authors": [
            {
                "name": "Wei Yang",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Liusheng Huang",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            },
            {
                "name": "Miaomiao Tian",
                "org": "University of Science and Technology of China(University of Science and Technology of China,Univ. of Sci. and Technol. of China),Hefei,China"
            }
        ],
        "venue": "Applied Mathematics and Information Sciences",
        "year": 2013
    },
    "cN9NZRH1": {
        "id": "cN9NZRH1",
        "title": "Two Novel and Secure Quantum ANDOS Schemes",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "miaomiao tian",
                "org": ""
            },
            {
                "name": "liusheng huang",
                "org": ""
            },
            {
                "name": "wei yang",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2013
    },
    "hJWmAzkq": {
        "id": "hJWmAzkq",
        "title": "Security analysis of a fuzzy identity-based encryption scheme.",
        "abstract": "",
        "keywords": [
            "cryptanalysis"
        ],
        "authors": [
            {
                "name": "Miaomiao Tian",
                "org": ""
            },
            {
                "name": "Liusheng Huang",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            }
        ],
        "venue": "Journal of Circuits, Systems, and Computers",
        "year": 2014
    },
    "F7I2fszv": {
        "id": "F7I2fszv",
        "title": "A privacy preserving scheme for change increment of electricity big data base on symmetric cryptography",
        "abstract": "",
        "keywords": [
            "real time systems",
            "indexes",
            "servers",
            "data privacy",
            "cryptography",
            "big data"
        ],
        "authors": [
            {
                "name": "yiwen nie",
                "org": "university of science and technology of china"
            },
            {
                "name": "wei yang",
                "org": "university of science and technology of china"
            },
            {
                "name": "liusheng huang",
                "org": "university of science and technology of china"
            },
            {
                "name": "xiaorong lu",
                "org": "university of science and technology of china"
            }
        ],
        "venue": "CCIS",
        "year": 2014
    },
    "qyULvWpx": {
        "id": "qyULvWpx",
        "title": "PS-TRUST: Provably secure solution for truthful double spectrum auctions",
        "abstract": "Truthful spectrum auctions have been extensively studied in recent years. Truthfulness makes bidders bid their true valuations, simplifying greatly the analysis of auctions. However, revealing one's true valuation causes severe privacy disclosure to the auctioneer and other bidders. To make things worse, previous work on secure spectrum auctions does not provide adequate security. In this paper, based on TRUST, we propose PS-TRUST, a provably secure solution for truthful double spectrum auctions. Besides maintaining the properties of truthfulness and special spectrum reuse of TRUST, PS-TRUST achieves provable security against semi-honest adversaries in the sense of cryptography. Specifically, PS-TRUST reveals nothing about the bids to anyone in the auction, except the auction result. To the best of our knowledge, PS-TRUST is the first provably secure solution for spectrum auctions. Furthermore, experimental results show that the computation and communication overhead of PS-TRUST is modest, and its practical applications are feasible.",
        "keywords": [
            "data privacy",
            "trust spectrum reuse",
            "communication overhead",
            "radio spectrum management",
            "privacy disclosure",
            "ps-trust",
            "telecommunication security",
            "provably secure solution for truthful double spectrum auctions",
            "semihonest adversary"
        ],
        "authors": [
            {
                "name": "Zhili Chen",
                "org": ""
            },
            {
                "name": "Liusheng Huang",
                "org": ""
            },
            {
                "name": "Lu Li",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Haibo Miao",
                "org": ""
            },
            {
                "name": "Miaomiao Tian",
                "org": ""
            },
            {
                "name": "Fei Wang",
                "org": ""
            }
        ],
        "venue": "INFOCOM",
        "year": 2014
    },
    "5MYZiBYE": {
        "id": "5MYZiBYE",
        "title": "Practical certificateless short signature scheme",
        "abstract": "Certificateless cryptography is an attractive paradigm for public key cryptography since it does not require certificates in traditional public key cryptography and also solves the inherent key escrow problem in identity-based cryptography. Currently, certificateless short signature is receiving significant attention from the public key cryptography research community as it is particularly useful in low-bandwidth communication environments. However, most of the certificateless short signature schemes only support low-level security. Recently, Choi et al. presented a certificateless short signature scheme and claimed that it is provably secure against super adversaries in the random oracle model. Unfortunately, in this paper, we show that their scheme is insecure even against a strong adversary. We then propose a new certificateless short signature scheme and prove that it is secure against strong adversaries. Compared with other certificateless short signature schemes, our scheme is more computationally efficient.",
        "keywords": [],
        "authors": [
            {
                "name": "Miaomiao Tian",
                "org": "School of Computer Science and Technology, University of Science and Technology of China, Hefei 230026, China"
            },
            {
                "name": "Liusheng Huang",
                "org": "Suzhou Institute for Advanced Study, University of Science and Technology of China, S ..."
            },
            {
                "name": "Wei Yang",
                "org": "School of Computer Science and Technology, University of Science and Technology of China, Hefei 230026, China"
            }
        ],
        "venue": "IJESDF",
        "year": 2014
    },
    "iWMiZF3U": {
        "id": "iWMiZF3U",
        "title": "On the security of an enhanced signature scheme",
        "abstract": "Currently, short signature is receiving significant attention since it is particularly useful in low-bandwidth communication environments. However, most of the short signature schemes are only based on one intractable assumption. Recently, Su presented an enhanced short signature scheme based on knapsack and bilinear pairing. He claimed that the signature scheme is secure in the random oracle model. Unfortunately, in this paper, we show that his scheme is insecure. Concretely, an adversary can forge a valid signature on any message with respect to any user's identity in Su's scheme.",
        "keywords": [
            "enhanced signature scheme",
            "significant attention",
            "short signature",
            "bilinear pairing",
            "enhanced short signature scheme",
            "signature scheme",
            "random oracle model",
            "short signature scheme",
            "valid signature",
            "low-bandwidth communication environment",
            "intractable assumption",
            "cryptanalysis",
            "knapsack problem"
        ],
        "authors": [
            {
                "name": "Miaomiao Tian",
                "org": "School of Computer Science and Technology, University of Science and Technology of China, Hefei 230026, China"
            },
            {
                "name": "Liusheng Huang",
                "org": "School of Computer Science and Technology, University of Science and Technology of China, Hefei 230026, China"
            },
            {
                "name": "Wei Yang",
                "org": "School of Computer Science and Technology, University of Science and Technology of China, Hefei 230026, China"
            }
        ],
        "venue": "IJICT",
        "year": 2014
    },
    "OgXwCoj1": {
        "id": "OgXwCoj1",
        "title": "Privacy preserving big histogram aggregation for spatial crowdsensing.",
        "abstract": "The popularity of mobile devices has far expanded the application scenarios of spatial crowdsensing, due to its ability to provide fine-grained multi dimensional sensor readings associated with location information. Privacy is one of the fundamental issues in crowdsensing, as these location-based sensor readings may reveal identities or activities of participants. In this paper, we adopts the state-of-art location privacy definition geo-indistinguishability, provide an efficient and effective privacy preserving histogram aggregation mechanism BFMM (Bit Flipping Matrix Mechanism) for fine-grained multi dimensional location-based data. Theoretical analyses and experimental results demonstrate the efficiency and effectiveness of our approach for fine-grained multidimensional location-based data. Specifically, the aggregation accuracy of our approach averagely outperforms existing methods by a factor of number of buckets in the histogram.",
        "keywords": [],
        "authors": [
            {
                "name": "Shaowei Wang",
                "org": ""
            },
            {
                "name": "Liusheng Huang",
                "org": ""
            },
            {
                "name": "Pengzhan Wang",
                "org": ""
            },
            {
                "name": "Yao Shen",
                "org": ""
            },
            {
                "name": "Hongli Xu",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            }
        ],
        "venue": "IPCCC",
        "year": 2015
    },
    "RK0f6vK4": {
        "id": "RK0f6vK4",
        "title": "Towards Preserving Worker Location Privacy in Spatial Crowdsourcing.",
        "abstract": "Spatial Crowdsourcing (SC) nowadays has become a popular research topic studying how to outsource a set of spatial-temporal tasks to workers at specific locations. However, there exists a significant security concern: existing location privacy techniques are not applicable to SC. In this paper, we focus on protecting the worker location privacy against the semi-honest adversaries model while preserving the functionality of SC system. By introducing a semi-honest third party and using additive homomorphic encryption, we present a secure task assignment protocol for SC. More specifically, we propose an efficient protocol to securely compute the worker travel cost and select minimum cost worker in the encrypted domain, which reveals nothing about location privacy. We theoretically analyze that our protocol is secure as all encrypted private data are computationally indistinguishable. Extensive experimental results on real-world and synthetic datasets show that the proposed protocol can protect worker location privacy while keeping high task assignment rate.",
        "keywords": [],
        "authors": [
            {
                "name": "Yao Shen",
                "org": ""
            },
            {
                "name": "Liusheng Huang",
                "org": ""
            },
            {
                "name": "Lu Li",
                "org": ""
            },
            {
                "name": "Xiaorong Lu",
                "org": ""
            },
            {
                "name": "Shaowei Wang",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            }
        ],
        "venue": "GLOBECOM",
        "year": 2015
    },
    "bSRzkSpd": {
        "id": "bSRzkSpd",
        "title": "Efficient Privacy-Preserving Aggregation for Mobile Crowdsensing",
        "abstract": "",
        "keywords": [
            "noise",
            "encryption",
            "privacy",
            "mobile communication",
            "protocols",
            "data privacy"
        ],
        "authors": [
            {
                "name": "mengdi huai",
                "org": ""
            },
            {
                "name": "liusheng huang",
                "org": ""
            },
            {
                "name": "yue sun",
                "org": ""
            },
            {
                "name": "wei yang",
                "org": ""
            }
        ],
        "venue": "BDCloud",
        "year": 2015
    },
    "ud75sXIS": {
        "id": "ud75sXIS",
        "title": "Hamburger attack: A collusion attack against privacy-preserving data aggregation schemes.",
        "abstract": "Performing efficient data aggregation while keeping the property of privacy preservation of user-related data is of high concern. Extensive research has been conducted to address this problem in multiple areas. As a fact, the security of a number of privacy-preserving protocols are threatened by collusion between participants. Therefore, security analysis plays a fundamental role in privacy-preserving data aggregation protocols. In this paper, we present a new kind of collusion attack strategy called Hamburger Attack. It is of logical simplicity, but has the advantage of being effective and efficient. We employ it to check the security of several existing privacy-preserving data aggregation schemes. We show that under hamburger attack, some prior privacy-preserving data aggregation protocols will disclose part, even all, of the private data that they intended to protect. On the other hand, the hamburger attack is beneficial to designing new privacy-preserving data aggregation schemes. It can assist them in avoiding this kind of collusion attack.",
        "keywords": [],
        "authors": [
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Liusheng Huang",
                "org": ""
            },
            {
                "name": "Lu Li",
                "org": ""
            },
            {
                "name": "Mingjun Xiao",
                "org": ""
            },
            {
                "name": "Xiaorong Lu",
                "org": ""
            },
            {
                "name": "Yao Shen",
                "org": ""
            },
            {
                "name": "Youwen Zhu",
                "org": ""
            }
        ],
        "venue": "IWQoS",
        "year": 2015
    },
    "6VVMcABI": {
        "id": "6VVMcABI",
        "title": "Privacy-Preserving Naive Bayes Classification.",
        "abstract": "In this paper, we propose differentially private protocols for Naive Bayes classification over distributed data. Compared with existing works, the privacy and security models in the proposed protocols are stronger: firstly, both the miner and parties can be arbitrarily malicious and can collude with each other to violate the remaining honest parties privacy; secondly, all communication channels between them can be assumed to be insecure. Specifically, we build a guarantee of differential privacy into the cryptographic construction so that the proposed protocols can tolerate collusions and resist eavesdropping attacks which are caused by insecure communication channels. Additionally, the proposed protocols can be implemented at lower computation and communication costs, and some extensions to our protocols e.g. supporting parties dynamic joins or leaves are also proposed in this paper. Both theoretical analysis and simulation results show that the proposed privacy-preserving protocols for Naive Bayes have strong security and better classification performance than the standard one.",
        "keywords": [],
        "authors": [
            {
                "name": "Mengdi Huai",
                "org": ""
            },
            {
                "name": "Liusheng Huang",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Lu Li",
                "org": ""
            },
            {
                "name": "Mingyu Qi",
                "org": ""
            }
        ],
        "venue": "KSEM",
        "year": 2015
    },
    "3HYSrNvj": {
        "id": "3HYSrNvj",
        "title": "Personalized Privacy-Preserving Data Aggregation for Histogram Estimation.",
        "abstract": "Histogram estimation is one of the fundamental tasks in crowdsourcing data aggregation. Since contributing data reveal more or less information about individualsu0027 identifications and activities, participants need to preserve privacy of data according to their own levels of privacy concern. However, most of the existing work only aggregates data with an identical privacy level. In this paper, we propose an aggregation scheme for histogram estimation, wherein participants can publish their data at personalized differential-privacy levels. The aggregator also benefits from potential wider engagement or more honest data. Specially, since privacy levels under personalized privacy policy are sensitive information for participants, our scheme permits participants to keep their privacy levels secret even from the aggregator. We also show how to further optimize the estimation accuracy under given privacy levels by choosing specific randomization strategies.",
        "keywords": [],
        "authors": [
            {
                "name": "Shaowei Wang",
                "org": ""
            },
            {
                "name": "Liusheng Huang",
                "org": ""
            },
            {
                "name": "Miaomiao Tian",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Hongli Xu",
                "org": ""
            },
            {
                "name": "Hansong Guo",
                "org": ""
            }
        ],
        "venue": "GLOBECOM",
        "year": 2015
    },
    "Cfc7TdfX": {
        "id": "Cfc7TdfX",
        "title": "Private Range Queries on Outsourced Databases",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "lu li",
                "org": "university of science and technology of china"
            },
            {
                "name": "liusheng huang",
                "org": "university of science and technology of china"
            },
            {
                "name": "an liu",
                "org": "soochow university"
            },
            {
                "name": "y shen",
                "org": "university of science and technology of china"
            },
            {
                "name": "wei yang",
                "org": "university of science and technology of china"
            },
            {
                "name": "shengnan shao",
                "org": ""
            }
        ],
        "venue": "web age information management",
        "year": 2015
    },
    "AEuXjkdL": {
        "id": "AEuXjkdL",
        "title": "Protecting Location Privacy in Spatial Crowdsourcing.",
        "abstract": "Recently, spatial crowdsourcing has attracted wide attention in both the research community and industry, one of which is the eMarket platform. It enables requesters to release spatial tasks (i.e., tasks related to a location) and expect them to be performed by workers (i.e., users with smart mobile devices). One of the key functions of such platform is spatial tasks assignment. The traditional solutions to the tasks assignment problem require workers to disclose their locations to the spatial crowdsourcing server (SC-server), which are untrustworthy entities. In this paper, we employ the peer-to-peer spatial K-anonymity to protect the workers’ location privacy. However, it will result in the consequence that various spatial tasks can’t be performed. To improve the spatial task assignment, we propose an optimized scheme for spatial task assignment without compromising the workers’ location privacy, and verify the effect through our experiments.",
        "keywords": [],
        "authors": [
            {
                "name": "Jie Hu",
                "org": ""
            },
            {
                "name": "Liusheng Huang",
                "org": ""
            },
            {
                "name": "Lu Li",
                "org": ""
            },
            {
                "name": "Mingyu Qi",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            }
        ],
        "venue": "APWeb Workshops",
        "year": 2015
    },
    "vcACx3jQ": {
        "id": "vcACx3jQ",
        "title": "A novel comprehensive steganalysis of transmission control protocol/Internet protocol covert channels based on protocol behaviors and support vector machine: A novel comprehensive steganalysis of transmission control protocol/Internet protocol covert channels based on protocol behaviors and support vector m",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "wei yang",
                "org": ""
            },
            {
                "name": "xiaorong lu",
                "org": ""
            },
            {
                "name": "y shen",
                "org": ""
            },
            {
                "name": "liusheng huang",
                "org": ""
            }
        ],
        "venue": "Security and Communication Networks",
        "year": 2015
    },
    "ZSWl6m5o": {
        "id": "ZSWl6m5o",
        "title": "STRUCTURE: A Strategyproof Double Auction for Heterogeneous Secondary Spectrum Markets.",
        "abstract": "Auction has been regarded as one of the promising methods for the scarce resources allocation due to its fairness. Thus, spectrum auction is an efficient way to allocate licensed spectrum to new demanders for mitigating the spectrum scarcity. Most of the existing studies assume that the spectrum resources are homogeneous. However, spectrums with different frequencies are intrinsically heterogeneous due to their different licensed areas and interference ranges. In this paper, we concentrate on the heterogeneity of spectrum resources and propose a strategyproof double auction mechanism STRUCTURE. The STRUCTURE assumes that all the buyers are selfish and rational, and they will submit their bids for each interested spectrum. To achieve the strategyproofness, many existing double spectrum auction mechanisms adopt the bid-independent methods to construct buyer groups, which may cause unfairness for the buyers with high bid values. To tackle this, we turn to choose a bid-related buyer group construction algorithm, which is more suitable for the laws of market and can further avoid the collusion between buyers. After that, we propose a collusion-free allocation mechanism and a bid-independent payment mechanism to ensure the strategyproofness for both buyers and sellers. Simulation results show that the proposed mechanism significantly improves the spectrum utilization with low running time. Furthermore, we also find that the buyers with higher bid values have a higher winning ratio than the buyers with low bids in the STRUCTURE.",
        "keywords": [],
        "authors": [
            {
                "name": "Yu-e Sun",
                "org": ""
            },
            {
                "name": "He Huang",
                "org": ""
            },
            {
                "name": "Miaomiao Tian",
                "org": ""
            },
            {
                "name": "Zehao Sun",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Hansong Guo",
                "org": ""
            },
            {
                "name": "Liusheng Huang",
                "org": ""
            }
        ],
        "venue": "ICA3PP",
        "year": 2015
    },
    "EePJJgj7": {
        "id": "EePJJgj7",
        "title": "Spectrum Allocation Mechanisms in Wireless Networks with Performance Guarantee.",
        "abstract": "1School of Urban Rail Transportation, Soochow University, P. R. China, 215131 2School of Computer Science and Technology, Soochow University, P. R. China, 215006 3Department of Computer Science, Illinois Institute of Technology, United States, 60616 4Tsinghua National Laboratory for Information Science and Technology (TNLIST), Tsinghua University, P.R. China, 100084 5School of Computer Science and Technology, University of Science and Technology of China, P. R. China, 230027",
        "keywords": [],
        "authors": [
            {
                "name": "Yu-e Sun",
                "org": ""
            },
            {
                "name": "He Huang",
                "org": ""
            },
            {
                "name": "Xiang-Yang Li",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Hongli Xu",
                "org": ""
            },
            {
                "name": "Fanzhang Li",
                "org": ""
            },
            {
                "name": "Liusheng Huang",
                "org": ""
            }
        ],
        "venue": "Ad Hoc & Sensor Wireless Networks",
        "year": 2015
    },
    "lm3oclnJ": {
        "id": "lm3oclnJ",
        "title": "Secure double spectrum auctions.",
        "abstract": "Unlike traditional auction schemes that do not take security into account, a good secure auction scheme first has to satisfy the following two properties: 1) correctness: the auction result should be the same as the result using traditional correct schemes; 2) security: during the auction process, the final result is the only information revealed to the participants. Furthermore, the secure auction scheme should be efficient enough so that the final result can be determined within a reasonable time. Existing works mainly deal with single-sided spectrum auction, and are not totally secure though claimed to be secure. For example, in [2], the auctioneer can easily know the sums of bids for all the possible allocations, and in [3], the auctioneer can obtain the bids of all buyer groups and their ranking order in the auction. This kind of information is sensitive and should be kept secret. In a very timely recent study [4], the authors propose PS-TRUST, a solution for secure double spectrum auction based on TRUST [5]. To our best knowledge, this is the first work that achieves both correctness and security for secure spectrum auction. Unfortunately, the efficiency of this work is not satisfactory.",
        "keywords": [],
        "authors": [
            {
                "name": "Lu Li",
                "org": ""
            },
            {
                "name": "Liusheng Huang",
                "org": ""
            },
            {
                "name": "An Liu",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Yao Shen",
                "org": ""
            },
            {
                "name": "Bing Leng",
                "org": ""
            }
        ],
        "venue": "IWQoS",
        "year": 2015
    },
    "7N9CxQkU": {
        "id": "7N9CxQkU",
        "title": "Private Range Queries on Outsourced Databases.",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Lu Li",
                "org": ""
            },
            {
                "name": "Liusheng Huang",
                "org": ""
            },
            {
                "name": "An Liu",
                "org": ""
            },
            {
                "name": "Yao Shen",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Shengnan Shao",
                "org": ""
            }
        ],
        "venue": "WAIM",
        "year": 2015
    },
    "jhZQfyQY": {
        "id": "jhZQfyQY",
        "title": "Deadline-sensitive opportunistic utility-based routing in cyclic mobile social networks",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Mingjun Xiao",
                "org": "institute for advanced study"
            },
            {
                "name": "Jie Wu",
                "org": "temple university"
            },
            {
                "name": "He Huang",
                "org": "soochow university"
            },
            {
                "name": "Liusheng Huang",
                "org": "institute for advanced study"
            },
            {
                "name": "Wei Yang",
                "org": "institute for advanced study"
            }
        ],
        "venue": "IEEE Communications Society Conference on Sensor and Ad Hoc Communications and Networks",
        "year": 2015
    },
    "3iqZpZZ2": {
        "id": "3iqZpZZ2",
        "title": "Concealed in the Internet: A Novel Covert Channel with Normal Traffic Imitating.",
        "abstract": "Covert channel in network protocols has been an area absorbing great interests for many years in secret transmission. Recently, covert channels based on packet length have become a new preference among researchers in this field because of their excellent performance in simulating statistical features of network packets in real world. However, few approaches which can embed secret information with great security ensured has been worked out by so far. Therefore, in this paper, we analyze the traffic stream of UDP packets, several storage features of data files, then propose a novel network steganography scheme based on IP address, UDP packet length in order to overcome the drawbacks of existing schemes. A comprehensive set of corresponding experiment results show that the proposed covert channel follows the normal traffic statistical features well, thus ensures more security than that of the existing algorithms.",
        "keywords": "",
        "authors": [
            {
                "name": "Xiaorong Lu",
                "org": "University of Science and Technology of China"
            },
            {
                "name": "Liusheng Huang",
                "org": "University of Science and Technology, Sana'a"
            },
            {
                "name": "Wei Yang",
                "org": "University of Science and Technology of China"
            },
            {
                "name": "Yao Shen",
                "org": "University of Science and Technology of China"
            }
        ],
        "venue": "UIC/ATC/ScalCom/CBDCom/IoP/SmartWorld",
        "year": 2016
    },
    "g9u9DRhc": {
        "id": "g9u9DRhc",
        "title": "Geospatial Streams Publish with Differential Privacy.",
        "abstract": "Continuous releasing geospatial data is benefiting numerous areas, such as information push service, traffic scheduling and task assignment in crowdsourcing, etc. This kind of data is generated by people using positioning service in daily life, from which much sensitive information can be derived. Differential privacy is a strong theoretical and practical tool to provide protection; it has already been used on streams composing by datasets with fixed attributes. However, there is limited work on geospatial stream releasing with dynamic scopes for the requirement of accurate query. In this paper, aiming at achieving privacy protection of real-time geospatial synopsis with high utility, we introduce a method, called Realtime Geospatial Publish (RGP), which adopts differential privacy to geospatial stream with a new structure k-memo. We prove the privacy and utility of RGP theoretically and show the improvement of utility by experimental comparison with existing approaches on real datasets.",
        "keywords": "",
        "authors": [
            {
                "name": "Yiwen Nie",
                "org": "University of Science and Technology of China"
            },
            {
                "name": "Liusheng Huang",
                "org": "University of Science and Technology of China"
            },
            {
                "name": "Zongfeng Li",
                "org": "University of Science and Technology of China"
            },
            {
                "name": "Shaowei Wang",
                "org": "University of Science and Technology of China"
            },
            {
                "name": "Zhenhua Zhao",
                "org": "University of Science and Technology of China"
            },
            {
                "name": "Wei Yang",
                "org": "University of Science and Technology of China"
            },
            {
                "name": "Xiaorong Lu",
                "org": "University of Science and Technology of China"
            }
        ],
        "venue": "CollaborateCom",
        "year": 2016
    },
    "S02dFMpq": {
        "id": "S02dFMpq",
        "title": "Privacy-Preserving Collaborative Web Services QoS Prediction via Yao's Garbled Circuits and Homomorphic Encryption.",
        "abstract": "Collaborative Web services QoS prediction has become an important tool for the generation of accurate personalized QoS which is a cornerstone of most QoS-based approaches for Web services selection and composition. While a number of achievements have been attained on the study of improving the accuracy of collaborative QoS prediction, little work has been done for protecting user privacy in this process. In this paper, we propose a privacy-preserving collaborative QoS prediction framework which can protect the private data of users while retaining the ability of generating accurate QoS prediction. We combine Yaou0027s garbled circuit and additively homomorphic encryption via additively secret sharing to address non-linear computations required in the process of QoS prediction. We implement the proposed framework based on FasterGC, an open source implementation of Yaou0027s garbled circuit, and conduct extensive simulations to study its performance. Simulation results, together with theoretical security and complexity analysis, show that privacy-preserving QoS prediction can be efficiently achieved in our framework.",
        "keywords": [],
        "authors": [
            {
                "name": "Lu Li",
                "org": ""
            },
            {
                "name": "An Liu",
                "org": ""
            },
            {
                "name": "Qing Li",
                "org": ""
            },
            {
                "name": "Liusheng Huang",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Guanfeng Liu",
                "org": ""
            }
        ],
        "venue": "J. Web Eng.",
        "year": 2016
    },
    "L8yv4Gdf": {
        "id": "L8yv4Gdf",
        "title": "Private Weighted Histogram Aggregation in Crowdsourcing.",
        "abstract": "Histogram is one of the fundamental aggregates in crowdsourcing data aggregation. In a crowdsourcing aggregation task, the potential value or importance of each bucket in the histogram may differs, especially when the number of buckets is relatively large but only a few of buckets are of great interests. This is the case weighted histogram aggregation is needed. On the other hand, privacy is a critical issue in crowdsourcing, as data contributed by participants may reveal sensitive information about individuals. In this paper, we study the problem of privacy-preserving weighted histogram aggregation, and propose a new local differential-private mechanism, the bi-parties mechanism, which exploits the weight imbalances among buckets in histogram to minimize weighted error. We provide both theoretical and experimental analyses of the mechanism, specifically, the experimental results demonstrate that our mechanism can averagely reduce (20,%) of weighted square error of estimated histograms compared to existing approaches (e.g. randomized response mechanism, exponential mechanism).",
        "keywords": "",
        "authors": [
            {
                "name": "Shaowei Wang",
                "org": ""
            },
            {
                "name": "Liusheng Huang",
                "org": ""
            },
            {
                "name": "Pengzhan Wang",
                "org": ""
            },
            {
                "name": "Hou Deng",
                "org": ""
            },
            {
                "name": "Hongli Xu",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            }
        ],
        "venue": "WASA",
        "year": 2016
    },
    "XIpm94yg": {
        "id": "XIpm94yg",
        "title": "Temporal-Spatial Aggregated Urban Air Quality Inference with Heterogeneous Big Data.",
        "abstract": "Recently air quality information has drawn much attention from public and researchers as deteriorated air quality extremely damages human health. Meanwhile the limiting number of air quality monitor stations and complexity of influencing factors on air quality raise the starving demand on future air quality prediction. In this paper we propose a temporal-spatial aggregated urban air quality inference framework using the heterogeneous temporal and spatial datasets to infer the future air quality. We deeply analyse the influencing factors on air quality in terms of temporal and spatial features and then elaborately design a linear regression-based inference model with offline parameters learning and real time predicting. We not only estimate the parameters for our model itself, but also estimate the correlation parameters of single factor on the air quality in order that the model can make prediction on future air quality precisely. Based on real data sources, we appraise our approach with extensive experiments in Beijing and Suzhou. The results show that with the superior parameters learning, our model overmatches a series of state-of-art and commonly used approaches.",
        "keywords": "",
        "authors": [
            {
                "name": "Xiaorong Lu",
                "org": ""
            },
            {
                "name": "Yang Wang",
                "org": ""
            },
            {
                "name": "Liusheng Huang",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Yao Shen",
                "org": ""
            }
        ],
        "venue": "WASA",
        "year": 2016
    },
    "AC7yrxC9": {
        "id": "AC7yrxC9",
        "title": "Mutual Information Optimally Local Private Discrete Distribution Estimation.",
        "abstract": "Consider statistical learning (e.g. discrete distribution estimation) with local $epsilon$-differential privacy, which preserves each data provideru0027s privacy locally, we aim to optimize statistical data utility under the privacy constraints. Specifically, we study maximizing mutual information between a provideru0027s data and its private view, and give the exact mutual information bound along with an attainable mechanism: $k$-subset mechanism as results. The mutual information optimal mechanism randomly outputs a size $k$ subset of the original data domain with delicate probability assignment, where $k$ varies with the privacy level $epsilon$ and the data domain size $d$. After analysing the limitations of existing local private mechanisms from mutual information perspective, we propose an efficient implementation of the $k$-subset mechanism for discrete distribution estimation, and show its optimality guarantees over existing approaches.",
        "keywords": "",
        "authors": [
            {
                "name": "Shaowei Wang",
                "org": ""
            },
            {
                "name": "Liusheng Huang",
                "org": ""
            },
            {
                "name": "Pengzhan Wang",
                "org": ""
            },
            {
                "name": "Yiwen Nie",
                "org": ""
            },
            {
                "name": "Hongli Xu",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Xiang-Yang Li",
                "org": ""
            },
            {
                "name": "Chunming Qiao",
                "org": ""
            }
        ],
        "venue": "arXiv: Information Theory",
        "year": 2016
    },
    "s4HGMfhq": {
        "id": "s4HGMfhq",
        "title": "WiFinger: talk to your smart devices with finger-grained gesture.",
        "abstract": "In recent literatures, WiFi signals have been widely used to \\\"sense\\\" people's locations and activities. Researchers have exploited the characteristics of wireless signals to \\\"hear\\\" people's talk and \\\"see\\\" keystrokes by human users. Inspired by the excellent work of relevant scholars, we turn to explore the field of human-computer interaction using finger-grained gestures under WiFi environment. In this paper, we present Wi-Finger - the first solution using ubiquitous wireless signals to achieve number text input in WiFi devices. We implement a prototype of WiFinger on a commercial Wi-Fi infrastructure. Our scheme is based on the key intuition that while performing a certain gesture, the fingers of a user move in a unique formation and direction and thus generate a unique pattern in the time series of Channel State Information (CSI) values. WiFinger is deigned to recognize a set of finger-grained gestures, which are further used to realize continuous text input in off-the-shelf WiFi devices. As the results show, WiFinger achieves up to 90.4% average classification accuracy for recognizing 9 digits finger-grained gestures from American Sign Language (ASL), and its average accuracy for single individual number text input in desktop reaches 82.67% within 90 digits.",
        "keywords": "",
        "authors": [
            {
                "name": "Hong Li",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Jianxin Wang",
                "org": ""
            },
            {
                "name": "Yang Xu",
                "org": ""
            },
            {
                "name": "Liusheng Huang",
                "org": ""
            }
        ],
        "venue": "UbiComp",
        "year": 2016
    },
    "hWQjF01u": {
        "id": "hWQjF01u",
        "title": "A Secure and Robust Covert Channel Based on Secret Sharing Scheme.",
        "abstract": "Network covert channel (referred to as network steganography) is a covert communication technique that uses the redundancies of network protocols to transfer secret information. While encryption only protects communication from being decoded by unauthorised parties, a covert channel aims to hide the very existence of the secret communication. More recently focus has shifted towards network protocols based covert channels because the huge amount of data and vast number of different protocols in the Internet seems ideal as a high-bandwidth vehicle for covert communication. However, few approaches which can embed secret information with both great security and robustness ensured have been worked out by so far. In this paper, we propose a novel packet length based covert channel exploiting the secret sharing scheme in order to overcome the drawbacks of existing schemes. A comprehensive set of corresponding experiment results and security analysis show that the proposed covert channel is provably secure and with great robustness than that of the existing algorithms.",
        "keywords": "",
        "authors": [
            {
                "name": "Xiaorong Lu",
                "org": ""
            },
            {
                "name": "Yang Wang",
                "org": ""
            },
            {
                "name": "Liusheng Huang",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Yao Shen",
                "org": ""
            }
        ],
        "venue": "APWeb",
        "year": 2016
    },
    "lzus1HgK": {
        "id": "lzus1HgK",
        "title": "WiCare: A Synthesized Healthcare Service System Based on WiFi Signals.",
        "abstract": "To help the independent-living elders or patients nursed in a single isolated ward, we propose a proof-of-concept prototype named WiCare, a non-intrusive and device-free healthcare service system based on ubiquitous WiFi signals. It extracts Channel State Information (CSI) from the physical layer and detects the unique variations of CSI values caused by human activities. We implement WiCare on two laptops equipped with the commercial 802.11n network interface cards. Two potential application scenarios are considered: a living room and a bedroom. The results demonstrate that the proposed scheme achieves overall recognition accuracies of 92.3 % in living room and 87.6 % in bedroom with low false positive rates. Moreover, WiCare can send alarm messages when the server recognizes the occurrences of emergency activities, which assist the users in getting help as quickly as possible.",
        "keywords": "",
        "authors": [
            {
                "name": "Hong Li",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Yang Xu",
                "org": ""
            },
            {
                "name": "Jianxin Wang",
                "org": ""
            },
            {
                "name": "Liusheng Huang",
                "org": ""
            }
        ],
        "venue": "ICSOC",
        "year": 2016
    },
    "ypEzZzE1": {
        "id": "ypEzZzE1",
        "title": "CAE: Collusion Attack Emulator for Privacy-Preserving Data Aggregation Schemes.",
        "abstract": "In a number of networking applications, preserving the privacy of user-related data in data aggregation schemes is a fundamental issue. As a fact, many privacy-preserving protocols can be guaranteed with security against individual attacks, but they may be threatened by collusion between participants. Therefore, security analysis, especially for collusion attack analysis, plays an essential role in privacy-preserving data aggregation protocols. There do exist a few collusion attack schemes on data aggregation protocols, but none study the internal security mechanism of these protocols. In this paper, to our best knowledge, we are the first to propose a new kind of collusion attack analysis tool, which is named CAE (Collusion Attack Emulator). We employ it to check and judge the security of several existing privacy-preserving data aggregation schemes. We first show that for an aggregation scheme which has been known to be vulnerable under collusion attack, we can use CAE to explain why it is insecure. Then we demonstrate the blind detection function of CAE, i.e., we do not know whether an aggregation protocol is secure beforehand, and employ CAE to check its security and (if the protocol cannot pass the CAE test and thus to be insecure) to find its loophole.",
        "keywords": "",
        "authors": [
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Liusheng Huang",
                "org": ""
            },
            {
                "name": "Xiaorong Lu",
                "org": ""
            },
            {
                "name": "Yao Shen",
                "org": ""
            }
        ],
        "venue": "SECON",
        "year": 2016
    },
    "3qmWCXZH": {
        "id": "3qmWCXZH",
        "title": "A Real Time Wireless Interactive Multimedia System.",
        "abstract": "Recent years, various interactive multimedia systems have been applied to relevant fields such as education, entertainment, etc. Researchers exploit sensors, computer vision, ultrasonic, and electromagnetic radiation to achieve human-computer interaction (HCI). This paper proposes an interactive wireless multimedia system which utilizes ubiquitous wireless signals to identify human motions around smart WiFi devices. Compared with related work, our system realizes interactions between human and computer without extra hardware devices. The system identifies human gestures around the smart devices (i.e., a laptop) equipped with the commercial 802.11n NIC, and it maps different gestures into distinguishable computer instructions. We build a proof-of-concept prototype using off-the-shelf laptop and evaluate the system in a laboratory environment with standard WiFi access points. The results show that our system detects human gesture with an accuracy over 95 % and it achieves an average gesture classification accuracy of 89 % for five different users.",
        "keywords": "",
        "authors": [
            {
                "name": "Hong Li",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Yang Xu",
                "org": ""
            },
            {
                "name": "Jianxin Wang",
                "org": ""
            },
            {
                "name": "Liusheng Huang",
                "org": ""
            }
        ],
        "venue": "APWeb",
        "year": 2016
    },
    "8rYghFKO": {
        "id": "8rYghFKO",
        "title": "Privacy Preserving Quantum Anonymous Transmission via Entanglement Relay",
        "abstract": "A Nature Research Journal",
        "keywords": "",
        "authors": [
            {
                "name": "Wei Yang",
                "org": "School of Computer Science and Technology, University of Science and Technology of China, Hefei, 230026, China"
            },
            {
                "name": "Liusheng Huang",
                "org": "School of Computer Science and Technology, University of Science and Technology of China, Hefei, 230026, China"
            },
            {
                "name": "Wei Yang",
                "org": "Suzhou Institute for Advanced Study, University of Science and Technology of China, Suzhou, 215123, China"
            },
            {
                "name": "Liusheng Huang",
                "org": "Suzhou Institute for Advanced Study, University of Science and Technology of China, Suzhou, 215123, China"
            },
            {
                "name": "Fang Song",
                "org": "Institute for Quantum Computing, University of Waterloo, 200 University Ave. West, Waterloo, Ontario, Canada."
            }
        ],
        "venue": "Scientific Reports",
        "year": 2016
    },
    "kkUkDRV7": {
        "id": "kkUkDRV7",
        "title": "A novel covert channel in LTE-A system",
        "abstract": "Long Term Evolution Advanced (LTE-A) is the fourth generation (4G) wireless cellular communication standard. A covert channel is a noticeable threat to network security because it is able to transfer data under the overt channel. In this paper, a new class of covert channel coined as SNsteg is proposed, designed for LTE-A system. The SNsteg peculiarly utilizes the feature of Sequence Number (SN) fields in the headers of protocol stacks such as RLC (Radio Link Control) and PDCP (Packet Data Convergence Protocol). Subsequently, there are some analyses and evaluations of this covert channel.",
        "keywords": "",
        "authors": [
            {
                "name": "Zhiqiang He",
                "org": "School of CS & Tech., USTC, Hefei, 230027, China"
            },
            {
                "name": "Liusheng Huang",
                "org": "School of CS & Tech., USTC, Hefei, 230027, China"
            },
            {
                "name": "Wei Yang",
                "org": "School of CS & Tech., USTC, Hefei, 230027, China"
            },
            {
                "name": "Zukui Wang",
                "org": "School of CS & Tech., USTC, Hefei, 230027, China"
            }
        ],
        "venue": "international conference on computer science and network technology",
        "year": 2016
    },
    "vgdXhr1Z": {
        "id": "vgdXhr1Z",
        "title": "AIS: An Inaudible Guider in Your Smartphone.",
        "abstract": "In the problem of indoor localization, acoustic schemes exhibit their superiority over radio ways for lower propagation speed of sound in the air. Recent studies upon acoustic positioning and tracking proposed a couple of solutions at millimetre level. Enlightened by the outstanding work of relevant scholars, we propose an acoustic-based interactive system (AIS) for commercial-off-the-shelf (COTS) smartphones, which senses users’ moving states and routes by estimating the Doppler effect of received ultra sound signals using off-the-shelf smartphones. The ultra sound stems from surrounding fixed speakers. We test the performance of AIS with commercial smartphones and speakers in two cases. In the results of our experiments, we can achieve (1.1%) false positive rate and (8.9%) false negative rate for trajectory identification.",
        "keywords": "",
        "authors": [
            {
                "name": "Xing Zhou",
                "org": "University of Science and Technology of China"
            },
            {
                "name": "Liusheng Huang",
                "org": "University of Science and Technology of China"
            },
            {
                "name": "Yang Xu",
                "org": "University of Science and Technology of China"
            },
            {
                "name": "Wei Yang",
                "org": "University of Science and Technology of China"
            }
        ],
        "venue": "WASA",
        "year": 2017
    },
    "8iZX97JI": {
        "id": "8iZX97JI",
        "title": "Achieving personalized and privacy-preserving range queries over outsourced cloud data.",
        "abstract": "With the increasing prevalence of cloud computing, data owners prefer to outsource their databases to the cloud. For the protection of data privacy, sensitive data have to be encrypted before outsourcing, which introduces much difficulty into effective data utilization. Most previous studies either suffer from privacy disclosure and low efficiency, or do not support personalized multidimensional range queries. In this paper, we focus on personalized private range queries over outsourced data. We propose a personalized and privacy-preserving private range query protocol (PPP), which uses bounding-box PIR (bbPIR) to trade access pattern privacy for flexible privacy and high efficiency, and satisfies various quality of service (QoS) requirements. To our best knowledge, PPP is the first to achieve personalized search according to owner-specified privacy-cost tradeoff. Furthermore, PPP is secure against semi-honest adversaries under known ciphertext model. Experimental results on real-world datasets show that PPP is efficient and able to achieve diverse QoS requirements.",
        "keywords": "",
        "authors": [
            {
                "name": "Yao Shen",
                "org": "School of Computer Science and Technology, University of Science and Technology of China, Hefei, China"
            },
            {
                "name": "Liusheng Huang",
                "org": "School of Computer Science and Technology, University of Science and Technology of China, Hefei, China"
            },
            {
                "name": "Wei Yang",
                "org": "School of Computer Science and Technology, University of Science and Technology of China, Hefei, China"
            }
        ],
        "venue": "ICC",
        "year": 2017
    },
    "ZwnzXhM1": {
        "id": "ZwnzXhM1",
        "title": "Personalized Classifier Ensemble Pruning Framework for Mobile Crowdsourcing.",
        "abstract": "Ensemble learning has been widely employed by mobile applications, ranging from environmental sensing to activity recognitions. One of the fundamental issue in ensemble learning is the trade-off between classification accuracy and computational costs, which is the goal of ensemble pruning. During crowdsourcing, the centralized aggregator releases ensemble learning models to a large number of mobile participants for task evaluation or as the crowdsourcing learning results, while different participants may seek for different levels of the accuracy-cost trade-off. However, most of existing ensemble pruning approaches consider only one identical level of such trade-off. In this study, we present an efficient ensemble pruning framework for personalized accuracy-cost trade-offs via multi-objective optimization. Specifically, for the commonly used linear-combination style of the trade-off, we provide an objective-mixture optimization to further reduce the number of ensemble candidates. Experimental results show that our framework is highly efficient for personalized ensemble pruning, and achieves much better pruning performance with objective-mixture optimization when compared to state-of-art approaches.",
        "keywords": "",
        "authors": [
            {
                "name": "Shaowei Wang",
                "org": ""
            },
            {
                "name": "Liusheng Huang",
                "org": ""
            },
            {
                "name": "Pengzhan Wang",
                "org": ""
            },
            {
                "name": "Hongli Xu",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            }
        ],
        "venue": "arXiv: Distributed, Parallel, and Cluster Computing",
        "year": 2017
    },
    "W2oeEGJ5": {
        "id": "W2oeEGJ5",
        "title": "Achieving fully privacy-preserving private range queries over outsourced cloud data.",
        "abstract": "Abstract   With the prevalence of cloud computing, data owners are motivated to outsource their databases to the cloud server. However, to preserve data privacy, sensitive private data have to be encrypted before outsourcing, which makes data utilization a very challenging task. Existing work either focus on keyword searches and single-dimensional range query, or suffer from inadequate security guarantees and inefficiency. In this paper, we consider the problem of multidimensional private range queries over encrypted cloud data. To solve the problem, we systematically establish a set of privacy requirements for multidimensional private range queries, and propose a multidimensional private range query (MPRQ) framework based on private block retrieval (PBR), in which data owners keep the query private from the cloud server. To achieve both efficiency and privacy goals, we present an efficient and fully privacy-preserving private range query (PPRQ) protocol by using batch codes and multiplication avoiding technique. To our best knowledge, PPRQ is the first to protect the query, access pattern and single-dimensional privacy simultaneously while achieving efficient range queries. Moreover, PPRQ is secure in the sense of cryptography against semi-honest adversaries. Experiments on real-world datasets show that the computation and communication overhead of PPRQ is modest.",
        "keywords": "",
        "authors": [
            {
                "name": "Yao Shen",
                "org": "School of Computer Science and Technology, USTC, China"
            },
            {
                "name": "Wei Yang",
                "org": "School of Computer Science and Technology, USTC, China"
            },
            {
                "name": "Lu Li",
                "org": ""
            },
            {
                "name": "Liusheng Huang",
                "org": "School of Computer Science and Technology, USTC, China"
            }
        ],
        "venue": "Pervasive and Mobile Computing",
        "year": 2017
    },
    "2Jj3CH0D": {
        "id": "2Jj3CH0D",
        "title": "A Hybrid Covert Channel Over LTE-A System",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Zukui Wang",
                "org": "University of Science and Technology of China"
            },
            {
                "name": "Liusheng Huang",
                "org": "University of Science and Technology of China"
            },
            {
                "name": "Wei Yang",
                "org": "University of Science and Technology of China"
            },
            {
                "name": "Zhiqiang He",
                "org": "University of Science and Technology of China"
            }
        ],
        "venue": "international conference on wireless communication and sensor networks",
        "year": 2017
    },
    "MnMEqir3": {
        "id": "MnMEqir3",
        "title": "Tribological Behavior of Aligned Single-Walled Carbon Nanotubes",
        "abstract": "",
        "keywords": [
            "adhesion",
            "contact",
            "friction",
            "molecular dynamics",
            "single-walled carbon nanotubes",
            "van der waals forces",
            "tribology",
            "atoms",
            "molecular dynamics simulation",
            "force"
        ],
        "authors": [
            {
                "name": "Xinling Ma",
                "org": ""
            },
            {
                "name": "Hongtao Wang",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            }
        ],
        "venue": "Journal of Engineering Materials and Technology-transactions of The Asme",
        "year": 2004
    },
    "lWaU3iHm": {
        "id": "lWaU3iHm",
        "title": "Nitriding simulation for polycrystals of grain size gradient",
        "abstract": "Low temperature nitriding on pure iron with surface mechanical attrition treatment [Science 299 (2003) 686] has been recently accomplished at 300 °C. The nitrogen concentration profile differs from that of the conventional crystalline iron. Our simulation indicates that the ultra-fine grain size and the gradient distribution hold the key for the appreciable nitriding profile obtained in the experiment.",
        "keywords": [
            "grain boundary diffusion",
            "simulation",
            "nanocrystalline materials",
            "iron",
            "grain size",
            "nanocrystalline material",
            "grain boundary",
            "nitrogen"
        ],
        "authors": [
            {
                "name": "Hongtao Wang",
                "org": "Department of Engineering Mechanics, Tsinghua University, Beijing 100084, China"
            },
            {
                "name": "Wei Yang",
                "org": ""
            }
        ],
        "venue": "Scripta Materialia",
        "year": 2004
    },
    "5AUdlDzM": {
        "id": "5AUdlDzM",
        "title": "Abnormal Tribological Behavior of Multiwalled Nanotube Rafts Part I: Aligned Rafts",
        "abstract": "",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Hongtao Wang",
                "org": ""
            },
            {
                "name": "Y. Huang",
                "org": ""
            }
        ],
        "venue": "Journal of Engineering Materials and Technology-transactions of The Asme",
        "year": 2005
    },
    "9cEZS9Lw": {
        "id": "9cEZS9Lw",
        "title": "A screw dislocation nucleated from a triple junction",
        "abstract": "Dislocation mechanism is still considered to be an effective way in plastic deformation of nanocrystalline materials. The possible nucleation of a screw dislocation from the triple junction is explored. The nucleation of a screw dislocation is found to be rather difficult from the triple junction with well-bonded grain boundaries due to the small singularity (0 to −1/3) introduced by the elasticity anisotropy. For the triple junction with a free sliding grain boundary, the stress singularity is higher than −0.5 and dislocations can be spontaneously nucleated for grain sizes less than 100 nm.",
        "keywords": [
            "singularity",
            "grain boundaries",
            "nanocrystalline",
            "dislocations",
            "triple junctions",
            "grain boundary",
            "plastic deformation",
            "grain size",
            "nanocrystalline material"
        ],
        "authors": [
            {
                "name": "Hongtao Wang",
                "org": "FML, Department of Engineering Mechanics, Tsinghua University, Beijing 100084, China"
            },
            {
                "name": "Wei Yang",
                "org": ""
            }
        ],
        "venue": "International Journal of Plasticity",
        "year": 2005
    },
    "3lVqXxd6": {
        "id": "3lVqXxd6",
        "title": "Abnormal Tribological Behavior of Multiwalled Nanotube Rafts Part II: Inclined Rafts",
        "abstract": "",
        "keywords": [
            "force",
            "tribology",
            "stress",
            "displacement",
            "friction"
        ],
        "authors": [
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Hongtao Wang",
                "org": ""
            },
            {
                "name": "Y. Huang",
                "org": ""
            }
        ],
        "venue": "Journal of Engineering Materials and Technology-transactions of The Asme",
        "year": 2005
    },
    "jE6uX44L": {
        "id": "jE6uX44L",
        "title": "The thermomutability of single-walled carbon nanotubes by constrained mechanical folding.",
        "abstract": "The thermomutability of single-walled carbon nanotubes (SWCNT) with an ultrahigh aspect ratio has been systematically investigated by molecular dynamics simulations. A constraining matrix is necessary to transform the tube-long Euler instability to a localized cross-section flattening which can effectively hinder phonon transportation at the throttling kinks. A thermal conductivity reduction of approximately 50% was obtained for a 100 nm (5, 5) SWCNT when embedded in a compliant matrix (E approximately 0.4 GPa). An even larger reduction (approximately 80%) can be achieved for a stiffer matrix (40 GPa). The thermal conductivity decreases abruptly at the buckling portion which further develops into folding and connected spirals. The constrained mechanical folding is highly desirable for realizing ultra-sensitive thermal sensors or switches.",
        "keywords": [
            "aspect ratio",
            "thermal conductivity",
            "cross section"
        ],
        "authors": [
            {
                "name": "Chuan Lin",
                "org": ""
            },
            {
                "name": "Hongtao Wang",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            }
        ],
        "venue": "Nanotechnology",
        "year": 2010
    },
    "7jkFG29R": {
        "id": "7jkFG29R",
        "title": "Grain boundary structure dependent fracture in nanocrystalline Au films",
        "abstract": "Nanocrystalline Au films were in situ strained in a high resolution transmission electron microscope, which demonstrated that the diffusion-assisted intergranular fracture was the dominant failure mode. Grain orientation with respect to grain boundaries (GBs) imposes important effect on the crack propagation and blunting. The low surface energy and high diffusion mobility of {111} planes lead to a notch-like crack. The stress concentration at the tip may help breaking {111} planes layer by layer and thus advance the crack. Cracks can be diverted from the preset path by GBs and grow into the grain interior, which has never been revealed by other experiments and molecular dynamics simulations. © 2011 Elsevier B.V. All rights reserved.",
        "keywords": [
            "deformation and fracture",
            "grain boundaries",
            "grain orientation",
            "nanocrystalline metals",
            "layer by layer",
            "crack propagation",
            "stress concentration",
            "grain boundary",
            "failure mode",
            "surface energy"
        ],
        "authors": [
            {
                "name": "Jiabin Liu",
                "org": "Department of Materials and Engineering, China Jiliang University, Hangzhou 310018, China"
            },
            {
                "name": "Anmin Nie",
                "org": "Institute of Applied Mechanics, Zhejiang University, Hangzhou 310027, China"
            },
            {
                "name": "Cezhou Dong",
                "org": "Institute of Applied Mechanics, Zhejiang University, Hangzhou 310027, China"
            },
            {
                "name": "Peng Wang",
                "org": "Institute of Applied Mechanics, Zhejiang University, Hangzhou 310027, China"
            },
            {
                "name": "Hongtao Wang",
                "org": ""
            },
            {
                "name": "Maosen Fu",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": "Institute of Applied Mechanics, Zhejiang University, Hangzhou 310027, China"
            }
        ],
        "venue": "Materials Letters",
        "year": 2011
    },
    "Pe51Ll6O": {
        "id": "Pe51Ll6O",
        "title": "In situ TEM study on crack propagation in nanoscale Au thin films",
        "abstract": "In situ straining in nanocrystalline Au thin films reveals a new fracture mechanism, i.e. crack propagation by atomic migration. The crack propagates by repetitively nucleating and moving atomic steps from the tip region to the crack rear. The stress concentration at the tip helps in the step nucleation process. The elastic energy density at the notch root decreases with increasing notch angle, which implies cracks with small angles can propagate along grain boundaries more easily.",
        "keywords": [
            "thin film",
            "fracture",
            "migration",
            "in situ microscopy",
            "crack propagation"
        ],
        "authors": [
            {
                "name": "Hongtao Wang",
                "org": ""
            },
            {
                "name": "Anmin Nie",
                "org": "Institute of Applied Mechanics, Zhejiang University, Hangzhou 310027, China"
            },
            {
                "name": "Jiabin Liu",
                "org": "Institute of Applied Mechanics, Zhejiang University, Hangzhou 310027, China"
            },
            {
                "name": "Peng Wang",
                "org": "Institute of Applied Mechanics, Zhejiang University, Hangzhou 310027, China"
            },
            {
                "name": "Wei Yang",
                "org": "Institute of Applied Mechanics, Zhejiang University, Hangzhou 310027, China"
            },
            {
                "name": "Bangdao Chen",
                "org": "State Key Laboratory for Manufacturing Systems Engineering, Xi’an Jiaotong University, Xi’an 710049, China"
            },
            {
                "name": "Hongzhong Liu",
                "org": ""
            },
            {
                "name": "Maosen Fu",
                "org": "School of Materials Science and Engineering, Northwestern Polytechnical University, Xi’an 710049, China"
            }
        ],
        "venue": "Scripta Materialia",
        "year": 2011
    },
    "nGTKrlgh": {
        "id": "nGTKrlgh",
        "title": "CORROSION PERFORMANCE OF MICRO-ARC-OXIDATION AND ELECTROPHORESIS COMPLEX COATINGS ON MAGNESIUM ALLOY",
        "abstract": "The complex process technology of micro-arc-oxidation and electrophoresis is a new surface treatment method.The corrosion resistance of this complex coatings on magnesium alloy is reviewed and the corrosion mechanism is studied.The corrosion resistance of the complex coatings is determined by the compactness of organic layer and the combination state beween the complex coatings.The corrosion resistance of the complex coating is better when the compactness is better and the binding energy is bigger.",
        "keywords": [
            "Magnesium alloy",
            "Corrosion resistance",
            "Corrosion mechanism",
            "Micro-arc-oxidation and electrophoresis"
        ],
        "authors": [
            {
                "name": "SHI Hui-ying",
                "org": "School of Material Science and Engineering,Xi'an University of Technology,Xi'an ,China"
            },
            {
                "name": "YANG Wei",
                "org": "School of Material Science and Engineering,Xi'an University of Technology,Xi'an ,China"
            },
            {
                "name": "JIANG Bai-ling",
                "org": "School of Material Science and Engineering,Xi'an University of Technology,Xi'an ,China"
            }
        ],
        "venue": "Corrosion & Protection",
        "year": 2007
    },
    "KNGfgTpq": {
        "id": "KNGfgTpq",
        "title": "Engineering applications of microarc oxidation and magnetron sputtering",
        "abstract": "The technical advantages in environment protection and property design,and behavior characteristics of coatings prepared by microarc oxidation and magnetron sputter ion plating were analyzed from the perspective of technical principles;the competitive advantages of metal products treated by the two technologies in terms of increased ratio of performance to cost were summarized;then the prospective functions of microarc oxidation and magnetron sputtering in weight-lighten and precision procedure of manufacturing industry were discussed in accordance with the technical principles and applications.Based on all above,it is expected that public attention on seeking good strategies for enlarging benefits to China′s manufacturing industry will be aroused.",
        "keywords": [
            "precision",
            "magnetron sputter",
            "microarc oxidation",
            "weight-lighten"
        ],
        "authors": [
            {
                "name": "JIANG Bai-ling",
                "org": "School of Material Science and Engineering,Xi′an University of Technology,Xi′an Shaanxi ,China"
            },
            {
                "name": "YANG Wei",
                "org": "School of Material Science and Engineering,Xi′an University of Technology,Xi′an Shaanxi ,China"
            },
            {
                "name": "SU Yang",
                "org": "School of Material Science and Engineering,Xi′an University of Technology,Xi′an Shaanxi ,China"
            }
        ],
        "venue": "Heat Treatment of Metals",
        "year": 2008
    },
    "S7I5QhSA": {
        "id": "S7I5QhSA",
        "title": "Action mechanism of solute ions on forming process of microarc oxidation coatings on aluminium alloy",
        "abstract": "LY12 aluminium alloy was processed by microarc oxidation in Na2CO3,Na2SiO3 and Na2SnO3 solutions using AC electrical source.The effects of solute ions on the surface morphologies and phases of aluminium alloy samples were investigated by SEM and XRD,respectively.The effect rules of arc starting and growing curves were contrastively studied.The results show that in the above three electrolytes,arc starting can occur easily in Na2SiO3 solution,and high impedance coating can be prepared in short time at low voltage.Arc starting phenomenon cannot happen in Na2SnO3 solution.The phenomenon of arc starting will occur easily when high impedance coating occurs on the surface of aluminium alloy sample.Growing curves of ceramic coatings have similar rule during forming microarc oxidation coating in Na2CO3 and Na2SiO3 solutions.The sample is dissolved by galvano-chemistry in Na2SnO3 solution and the ceramic coating cannot be formed.The necessary condition of occurring microarc oxidation phenomenon is that high impedance coating must be formed on the surface of aluminium alloy.",
        "keywords": [
            "solute ion",
            "high impedance coating",
            "microarc oxidation",
            "LY12 aluminium alloy"
        ],
        "authors": [
            {
                "name": "YANG Wei",
                "org": "School of Materials Science and Engineering,Xi'an University of Technology,Xi'an ,China"
            },
            {
                "name": "JIANG Bai-ling",
                "org": "School of Materials Science and Engineering,Xi'an University of Technology,Xi'an ,China"
            },
            {
                "name": "XIAN Lin-yun",
                "org": "School of Materials Science and Engineering,Xi'an University of Technology,Xi'an ,China"
            },
            {
                "name": "SHI Hui-ying",
                "org": "School of Materials Science and Engineering,Xi'an University of Technology,Xi'an ,China"
            }
        ],
        "venue": "The Chinese Journal of Nonferrous Metals",
        "year": 2009
    },
    "6Dqded2A": {
        "id": "6Dqded2A",
        "title": "Effects of solute ions on forming process of microarc oxidation coatings on magnesium alloy",
        "abstract": "AZ31 Magnesium alloy was processed by microarc oxidation in three electrolytes(NaF、NaCl and NaI) using AC electrical source.Effects of solute ions on the surface morphology and phases of the magnesium alloy samples were investigated by SEM and XRD,respectively.The composition of microarc oxidation coatings in the process of microarc oxidation was analyzed by XPS.The results show that microarc oxidation phenomenon is observed only in NaF solution.The deposit coating is composed of MgF_2 before microarc starting,and the final phases in the coating are MgF_2 and MgO after microarc starting.In NaCl or NaI solutions,no microarc oxidation phenomenon occurs,and no coating is formed.The necessary conditions of microarc oxidation is the formation of high impedance coatings on surface of the samples deposited by electrochemical reaction of metal cation generated by anode discharge and anion in the electrolyte.",
        "keywords": [
            "AZ31 magnesium alloy",
            "high impedance coatings",
            "solute ions",
            "microarc oxidation"
        ],
        "authors": [
            {
                "name": "YANG Wei",
                "org": "School of Material Science and Engineering,Xi'an University of Technology,Xi'an ,China"
            },
            {
                "name": "JIANG Bai-ling",
                "org": "School of Material Science and Engineering,Xi'an University of Technology,Xi'an ,China"
            },
            {
                "name": "XIAN Lin-yun",
                "org": "School of Material Science and Engineering,Xi'an University of Technology,Xi'an ,China"
            }
        ],
        "venue": "Transactions of Materials and Heat Treatment",
        "year": 2009
    },
    "IWuRctkb": {
        "id": "IWuRctkb",
        "title": "Unhomogeneity of Micro-morphology and Mechanical Properties of Oxidation Coatings on Aluminum Alloy",
        "abstract": "LY12 aluminum alloy was prepared by microarc oxidation in the silicate electrolyte using a DC electrical source.Varieties of micro-morphology elastic modulus,hardness and scratch resistance in different regions of ceramic coating on aluminum alloy were investigated by SPM and Nano Indenter XP equipped with a diamond tip,respectively.The results show that the elastic modulus and hardness of the ceramic coatings are obviously different from the theoretical values of Al_2O_3.Surface morphologies and performances of ceramic coating are not uniform.The density of the micropores in the TC region is denser and the average size of pores is smaller than those in TE region.Concretely,compared with TE region,the thickness,elastic modulus,hardness and critical load of ceramic coating in TC region are decreased by 25.0%,27.7%,25.6% and 8.50%.",
        "keywords": [
            "LY12 aluminum alloy",
            "mechanical property",
            "microarc oxidation",
            "micro-morphology"
        ],
        "authors": [
            {
                "name": "YANG Wei",
                "org": "School of Material Science and Engineering,Xi'an University of Technology, Xi'an ,China"
            },
            {
                "name": "JIANG Bai-ling",
                "org": "School of Material Science and Engineering,Xi'an University of Technology, Xi'an ,China"
            },
            {
                "name": "SHEN Wei-dian",
                "org": "Coating Research Institute,Eastern Michigan University,Michigan State 48197,America"
            },
            {
                "name": "LI Yao",
                "org": "Coating Research Institute,Eastern Michigan University,Michigan State 48197,America"
            }
        ],
        "venue": "Journal of Materials Science and Engineering",
        "year": 2009
    },
    "1aOAPpli": {
        "id": "1aOAPpli",
        "title": "Lossless evaluation of corrosion resistance for micro-arc oxidation ceramic coating on magnesium alloy",
        "abstract": "Ceramic coatings with the same thickness were prepared on magnesium alloy in the silicate solution under the constant voltage mode. The surface morphologies of ceramic coatings were observed by SEM. The corrosion rates of the coatings were evaluated by the method of corrosion proportion. The value of medium ullage tangent tanδ was measured by LCR-digital electric bridge. The effects of micro-are oxidation energy parameters on the surface morphologies of ceramic coatings were analyzed. Corresponding relations between the average value medium ullage tangent tanδ and surface morphologies were investigated. Furthermore, the dependence of the corrosion resistance of ceramic coatings on the value of tanδ was discussed. The results show that micropore apertures of the surface of ceramic coatings are decreased and the compactness is increased with increasing the frequency or decreasing the duty cycle;tanδ is increased linearly with decreasing the frequency and increasing the duty cycle. The corrosion resistance of ceramic coatings gets worse with increasing tanδ. As a result, the corrosion resistance of ceramic coatings evaluated lossless by tanδ is realized.",
        "keywords": [
            "Ceramic coatings",
            "Corrosion resistance",
            "Lossless evaluation",
            "Magnesium alloy",
            "Medium ullage tangent value"
        ],
        "authors": [
            {
                "name": "Wei Yang",
                "org": "Xi'an University of Technology(Xi'an University of Technology,Xi'an Univ. of Technol.),Xi An,China"
            },
            {
                "name": "SHI Hui-ying",
                "org": "Xi'an University of Technology(Xi'an University of Technology,Xi'an Univ. of Technol.),Xi An,China"
            },
            {
                "name": "JIANG Bai-ling",
                "org": "Xi'an University of Technology(Xi'an University of Technology,Xi'an Univ. of Technol.),Xi An,China"
            },
            {
                "name": "LI Jun-ming",
                "org": "Xi'an University of Technology(Xi'an University of Technology,Xi'an Univ. of Technol.),Xi An,China"
            }
        ],
        "venue": "Jinshu Rechuli/Heat Treatment of Metals",
        "year": 2009
    },
    "991kZNQ6": {
        "id": "991kZNQ6",
        "title": "Dependence of surface feature of aluminium alloy on growth process of microarc oxidation coating",
        "abstract": "The relevance of the impedance of deposited-layer and ceramic coating growth was discussed by using SEM, XPS and IM6e electrochemical workstation. The results show that solute ions are participated in forming the deposited-layer, and the composition, microstructure and impedance of this layer are different, which results in a difference of arc striking time and voltage during microarc oxidation (MAO). After arc striking occurring, the increase of the impedance of the sample is dependent on Al substrate changed into alumina, and a small amount of solute ions is participated in forming the ceramic coating. The insulation of the sample surface is increased by the prefab coating at the initial stage, which makes arc striking and growth process of microarc oxidation affected little by the kind and impedance of the prefab coating.",
        "keywords": [
            "Aluminium alloy",
            "Deposited layer",
            "Impedance value",
            "Microarc oxidation",
            "Prefab coating"
        ],
        "authors": [
            {
                "name": "Wei Yang",
                "org": "Xi'an University of Technology(Xi'an University of Technology,Xi'an Univ. of Technol.),Xi An,China"
            },
            {
                "name": "JIANG Bai-ling",
                "org": "Xi'an University of Technology(Xi'an University of Technology,Xi'an Univ. of Technol.),Xi An,China"
            },
            {
                "name": "SHI Hui-ying",
                "org": "Xi'an University of Technology(Xi'an University of Technology,Xi'an Univ. of Technol.),Xi An,China"
            },
            {
                "name": "XIAN Lin-yun",
                "org": "Xi'an University of Technology(Xi'an University of Technology,Xi'an Univ. of Technol.),Xi An,China"
            }
        ],
        "venue": "Zhongnan Daxue Xuebao (Ziran Kexue Ban)/Journal of Central South University (Science and Technology)",
        "year": 2010
    },
    "6TH56aCD": {
        "id": "6TH56aCD",
        "title": "Effect of characteristics of prefab coating on formation of microarc oxidation coating on aluminum alloy",
        "abstract": "LY12 aluminium alloy was processed by microarc oxidation (MAO) in NaCl and Na_2SiO_3 solutions with different concentrations of Na_2SiO_3 using AC electrical source. The effect of prefab coatings on arc starting and growth during MAO process was researched. The results show that a coating with high impedance value formed on the sample surface is a necessary condition for arc starting. The discharge of active electrode is restrained by prefab coating, which offers an unstable interface state for microarc discharge to shortening arc starting time and reducing the voltage. No significant effect of thickness and impedance of prefab coatings on arc starting time and voltage is observed. Whether the prefab coating is prepared on the sample surface, the curves of voltage-time during MAO is similar. The prefab coating is concerned with forming ceramic coating, which results in a fast growth of ceramic coating under the same energy output.",
        "keywords": [
            "Aluminium alloy",
            "Arc starting and growth",
            "Micro arc oxidation",
            "Prefab coating"
        ],
        "authors": [
            {
                "name": "YANG Wei",
                "org": "School of Material Science and Engineering, Xi′an University of Technology, Xi′an , China"
            },
            {
                "name": "JIANG Bai-ling",
                "org": "School of Material Science and Engineering, Xi′an University of Technology, Xi′an , China"
            },
            {
                "name": "SHI Hui-ying",
                "org": "School of Material Science and Engineering, Xi′an University of Technology, Xi′an , China"
            },
            {
                "name": "XIAN Lin-yun",
                "org": "School of Material Science and Engineering, Xi′an University of Technology, Xi′an , China"
            },
            {
                "name": "LI Jun-ming",
                "org": "School of Material Science and Engineering, Xi′an University of Technology, Xi′an , China"
            }
        ],
        "venue": "Transactions of Materials and Heat Treatment",
        "year": 2010
    },
    "ZcCTiUkG": {
        "id": "ZcCTiUkG",
        "title": "Structures refinement of Al-Zn-Mg-Cu-Cr alloy thick plates",
        "abstract": "An intermediate thermal-mechanical treatment (ITMT), which includes reinforced solid solution, over-aging, heavy strain by combination of multi-directional forging and rolling at warm temperature and re-crystallization by fast heating was proposed and studied for structure refining of Al-Zn-Mg-Cu-Cr alloy thick plates. The structures evolution laws and the mechanism of grain refining with the above ITMT were studied by means of OM, EDS and TEM. Then the qualifications of controlling the grain size under discontinuous re-crystallization were discussed. The results show that ITMT process can make Al-Zn-Mg-Cu-Cr alloy thick plates deform sufficiently and equally, also make the structure of re-crystallization refine effectively, though the rolling reduction is not more than 80%. The average re-crystallization grain size is refined to around 8 μm in the short transverse direction and 12 μm in the vertical or long transverse direction. Most of the secondary particles are refined to less than 3 μm. The mechanism of grain refining for ITMT can be summarized as: the fine, homogenous and equal-axial grains are refined by discontinuous re-crystallization, making full use of the heavy strain energy formed by the severe plastic deformation and the feasible size and distribution of secondary particles formed chiefly in the over-aging.",
        "keywords": [
            "Al-Zn-Mg-Cu-Cr alloy",
            "structure refinement",
            "thick plates",
            "discontinuous re-crystallization",
            "intermediate thermal-mechanical treatment (ITMT)"
        ],
        "authors": [
            {
                "name": "LIN Gao-yong",
                "org": "The Key Laboratory of Nonferrous Metals Materials Science and Engineering, Ministry of Education, School of Materials Science and Engineering, Central South University, Changsha , China"
            },
            {
                "name": "YANG Wei",
                "org": "The Key Laboratory of Nonferrous Metals Materials Science and Engineering, Ministry of Education, School of Materials Science and Engineering, Central South University, Changsha , China"
            },
            {
                "name": "SUN Li-ping",
                "org": "The Key Laboratory of Nonferrous Metals Materials Science and Engineering, Ministry of Education, School of Materials Science and Engineering, Central South University, Changsha , China"
            },
            {
                "name": "PENG Da-shu",
                "org": "The Key Laboratory of Nonferrous Metals Materials Science and Engineering, Ministry of Education, School of Materials Science and Engineering, Central South University, Changsha , China"
            }
        ],
        "venue": "The Chinese Journal of Nonferrous Metals",
        "year": 2008
    },
    "iWRHVxeg": {
        "id": "iWRHVxeg",
        "title": "Research Development of Quenching-induced Residual Stress of Aluminum Thick Plates",
        "abstract": "The forming mechanism and distribution of the quenching-induced residual stress of aluminum alloy thick plates are summarized.The development of research using FEM is also introduced.According to the results of ex- periment and numerical simulation,a local balanced stress and strain shift model for explaining the formation mecha- nism and distribution laws of quenching-induced residual stress in the aluminum alloy thick plates is proposed.Further- more,the main existing problems in research and the study direction are also pointed out.",
        "keywords": [
            "aluminum alloy",
            "quenching-induced residual stress",
            "forming mechanism",
            "thick plate",
            "FEM"
        ],
        "authors": [
            {
                "name": "LIN Gaoyong",
                "org": "School of Materials Science and Engineering,Center South University,Changsha "
            },
            {
                "name": "ZHENG Xiaoyan",
                "org": "School of Materials Science and Engineering,Center South University,Changsha "
            },
            {
                "name": "FENG Di",
                "org": "School of Materials Science and Engineering,Center South University,Changsha "
            },
            {
                "name": "YANG Wei",
                "org": "School of Materials Science and Engineering,Center South University,Changsha "
            },
            {
                "name": "PENG Dashu",
                "org": "School of Materials Science and Engineering,Center South University,Changsha "
            }
        ],
        "venue": "Materials Review",
        "year": 2008
    },
    "xFRX26UT": {
        "id": "xFRX26UT",
        "title": "Effects of heat treatment on nitrided layer of H13 tool steel",
        "abstract": "The microstructure and hardness of the layer of H13 tool steel gas-nitrided in different heat treatment conditions were studied by X-ray, SEM and micro-hardness test. The results show that, the thickness of nitrided layer was 0.24 mm with a compound layer 10 μm, surface hardness was HV950(HRC67), for the specimen, which was nitrided after 'quenching and twice tempering' and 'quenching and three-time tempering'. The compound layer mainly consisted of e-phase(Fe 2N), γ' -phase and Fe 3O 4, and diffusion layer consisted α-Fe, ε-phase(Fe 3N), γ'-phase and CrN. However, the specimen nitrided after 'quenching' and 'quenching and once tempering' couldn't have a nitrided layer of comprehensive properties.",
        "keywords": [
            "H13 tool steel",
            "Heat treatment conditions",
            "Nitrided layer"
        ],
        "authors": [
            {
                "name": "LIN Gao-yong",
                "org": "School of Information Science and Engineering(School of Metallurgical Science and Engineering,School of Physics Science and Technology,School of Information Science and Engineering),Changsha,China"
            },
            {
                "name": "ZHENG Xiao-yan",
                "org": "School of Information Science and Engineering(School of Metallurgical Science and Engineering,School of Physics Science and Technology,School of Information Science and Engineering),Changsha,China"
            },
            {
                "name": "Di Feng",
                "org": "School of Information Science and Engineering(School of Metallurgical Science and Engineering,School of Physics Science and Technology,School of Information Science and Engineering),Changsha,China"
            },
            {
                "name": "Wei Yang",
                "org": "School of Information Science and Engineering(School of Metallurgical Science and Engineering,School of Physics Science and Technology,School of Information Science and Engineering),Changsha,China"
            },
            {
                "name": "ZHANG Sheng-hua",
                "org": "School of Information Science and Engineering(School of Metallurgical Science and Engineering,School of Physics Science and Technology,School of Information Science and Engineering),Changsha,China"
            }
        ],
        "venue": "Kang T'ieh/Iron and Steel (Peking)",
        "year": 2008
    },
    "YBOgkE9a": {
        "id": "YBOgkE9a",
        "title": "Analysis of influence of extrusion times on total die wear based on Archard theory",
        "abstract": "Based on the fact that under discontinuous extrusion condition, former passes often have great effect on the next ones, so that the relationship between die wear of single process and total wear is not linear, the position with the largest amount of wear on the die surface was predicted, and the relationship between the extrusion times and the total die wear was estimated by combining modified Archard model which considered the influence of temperature on the die wear behaviors and finite element method (FEM) technology. As a result, an equation for evaluating the total die wear which considers the effects of extrusion times was established.",
        "keywords": [
            "Archard theory",
            "Die wear",
            "Extrusion",
            "Finite element method (FEM)"
        ],
        "authors": [
            {
                "name": "LIN Gao-yong",
                "org": "Central South University China(Central South University ^),Changsha,China"
            },
            {
                "name": "Di Feng",
                "org": "Central South University China(Central South University ^),Changsha,China"
            },
            {
                "name": "ZHENG Xiao-yan",
                "org": "Central South University China(Central South University ^),Changsha,China"
            },
            {
                "name": "Wei Yang",
                "org": "Central South University China(Central South University ^),Changsha,China"
            },
            {
                "name": "SUN Li-ping",
                "org": "Central South University China(Central South University ^),Changsha,China"
            }
        ],
        "venue": "Zhongnan Daxue Xuebao (Ziran Kexue Ban)/Journal of Central South University (Science and Technology)",
        "year": 2009
    },
    "KmdSvjjG": {
        "id": "KmdSvjjG",
        "title": "Experimental Research of Refining Impure-copper with Rare Earth Elements",
        "abstract": "Three kinds of self-prepared Cu-RE refining agents were used to refine impure-copper.The influences of rare earth(RE) elements on refinements and structures were studied by means of the plasma emission spectrum,EDS,OM and XRD.The results show that by adding proper amounts of Cu-RE refining agents into impure-coppers,the refinements of RE on impure-coppers are perfect.The impurity elements such as O,Pb,Bi,Sn,Al are reduced obviously.The dendrites of the RE-refined ingot are refined and the structure becomes more homogeneous.",
        "keywords": [
            "impure-copper",
            "structure",
            "Cu-RE refining agent",
            "chemical elements analysis"
        ],
        "authors": [
            {
                "name": "LIN Gao-yong",
                "org": "School of Materials Science and Engineering,Central South University,Changsha ,China"
            },
            {
                "name": "YANG Wei",
                "org": "School of Materials Science and Engineering,Central South University,Changsha ,China"
            },
            {
                "name": "ZHANG Zhen-feng",
                "org": "School of Materials Science and Engineering,Central South University,Changsha ,China"
            },
            {
                "name": "WEI Bi",
                "org": "Gaoxinzhangtong Limited Liability Company,Zhangjiagang ,China"
            },
            {
                "name": "ZHAO Xiang-wei",
                "org": "Gaoxinzhangtong Limited Liability Company,Zhangjiagang ,China"
            },
            {
                "name": "ZHANG Sheng-hua",
                "org": "School of Materials Science and Engineering,Central South University,Changsha ,China"
            }
        ],
        "venue": "Chinese Rare Earths",
        "year": 2009
    },
    "IsLyMFvL": {
        "id": "IsLyMFvL",
        "title": "Influence of trace rare earth elements on microstructure and corrosion resistance of hal77-2 copper alloy",
        "abstract": "Effects of trace rare earth (RE) elements on microstructure and mechanical properties of HAl77-2 Al-brass were analyzed by OM and conventional mechanical test. Static corrosion experiment was used to study the corrosion behavior of the Al-brass after adding RE addition and SEM, energy analysis and XRD were simultaneously used to investigate the corrosion product layer synthetically. It was demonstrated that adding RE to Al-brass could refine grain and increase strength, but decrease the elongation; The corrosion resistance of the RE-containing Al-brass was better than that of Al-brass without RE in NaCl (3.5 mass%) solution. The consequence of such good corrosion resistance was attributed to the formation of compact protective film on alloy surface which contained RE elements. The RE-contained film, which was composed of an inner Al 2O 3, RE oxide and an outer chloride or basic chloride of Cu, Zn, combined with the matrix firmly and was difficult to fall off from the alloy surface. While the addition of RE could not improve the corrosion resistance of Al-brass. in NaCl (3.5 mass%) +S 2- solution. Although the corrosion products layer was ameliorated due to the RE addition, the corrosion resistance of the alloy deteriorated yet owing to the severe embrittlement of the corrosion product layer caused by Cu 2S.",
        "keywords": [
            "Corrosion resistance",
            "HAl77-2 alloy",
            "Microstructure",
            "Rare earth"
        ],
        "authors": [
            {
                "name": "Gaoyong Lin",
                "org": "Central South University China(Central South University ^),Changsha,China"
            },
            {
                "name": "Wei Yang",
                "org": "Central South University China(Central South University ^),Changsha,China"
            },
            {
                "name": "Yingchun Wan",
                "org": "Central South University China(Central South University ^),Changsha,China"
            },
            {
                "name": "Pengjun Tang",
                "org": "Central South University China(Central South University ^),Changsha,China"
            },
            {
                "name": "Shenghua Zhang",
                "org": "Central South University China(Central South University ^),Changsha,China"
            }
        ],
        "venue": "Journal of the Chinese Society of Corrosion and Protection",
        "year": 2010
    },
    "r8uEjrps": {
        "id": "r8uEjrps",
        "title": "Influence of RE Content on Corrosion Behavior of BFe10-1-1 Alloy in Simulated Flowing Sea Water",
        "abstract": "The corrosion behavior of BFe10-1-1 alloy with different rare earth(RE) content in simulated flowing sea water was investigated by corrosion rate measurement,X-ray diffractometer and scanning electronic microscope(SEM).It was demonstrated that the corrosion rate of BFe10-1-1 alloy with the same chemical compositions in faster flow velocity of sea water was higher than that in lower flow velocity of sea water.Exfoliation corrosion was the prevalent corrosion mechanism when BFe10-1-1 alloy was in the flowing sea water.BFe10-1-1 alloy has the best corrosion resistance when the RE content is 0.04 mass%.The consequence of such good corrosion resistance is attributed to the formation of a compact protective film on the alloy surface which contains RE phases such as CeNi_5.The RE-contained film combines with other corrosion products firmly,which has few microcracks and good adhasive to the substrate alloy surface in the flowing sea water.Whereas,the amount of RE elements addition higher than 0.04 mass%deteriorates the corrosion resistance of the alloys.",
        "keywords": [
            "BFe10-1-1 alloy",
            "Corrosion resistance",
            "Exfoliation corrosion",
            "RE elements"
        ],
        "authors": [
            {
                "name": "LIN Gao-yong",
                "org": " 1.Key Laboratory of Nonferrous Metals Materials Science and Engineering,Ministry of Education"
            },
            {
                "name": "WAN Ying-chun",
                "org": " 1.Key Laboratory of Nonferrous Metals Materials Science and Engineering,Ministry of Education"
            },
            {
                "name": "YANG Wei",
                "org": " 1.Key Laboratory of Nonferrous Metals Materials Science and Engineering,Ministry of Education"
            },
            {
                "name": "WEI Bi",
                "org": "Gao Xin Zhangtong Limited Liability Company,Jiangsu "
            },
            {
                "name": "ZHANG Sheng-hua",
                "org": " 1.Key Laboratory of Nonferrous Metals Materials Science and Engineering,Ministry of Education"
            },
            {
                "name": "TANG Peng-jun",
                "org": " 1.Key Laboratory of Nonferrous Metals Materials Science and Engineering,Ministry of Education"
            }
        ],
        "venue": "Corrosion Science and Protection Technology",
        "year": 2010
    },
    "qrpO4GdA": {
        "id": "qrpO4GdA",
        "title": "Research on the Development Levels of Main Trades of Shanxi Industry",
        "abstract": "By the means of principal component analysis,cluster analysis and factor analysis,the data of the 34 main trades of Shanxi industry has been studied.From the above analysis,we can get all the comprehensive economic indexes,which reflect the economic efficiency and the industry scale.Further,after sorting all the trades,the situation of all the levels of industrial development and its distribution can be obtained.It provides a theoretical foundation for the strategy of overall economic development.",
        "keywords": [
            "principal component analysis",
            "factor analysis",
            "cluster analysis"
        ],
        "authors": [
            {
                "name": "SHI Jin-feng",
                "org": "School of Mathematics Science,Shanxi University,Taiyuan, China"
            },
            {
                "name": "YANG Wei",
                "org": "School of Mathematics Science,Shanxi University,Taiyuan, China"
            }
        ],
        "venue": "Journal of Taiyuan University of Science and Technology",
        "year": 2006
    },
    "ZZzMeEp1": {
        "id": "ZZzMeEp1",
        "title": "The Research of Growth Bound of the Perturbated C_(0~-) semigroupunder Bounded Operator",
        "abstract": "In this paper,the author studies the sufficient conditions for the growth bound ω1 of C0-semigroup(S(t))t≥0,more than or less than the given constant ω,where(S(t))t≥0 is the perturbated semigroup by C0-semigroup(T(t))t≥0 under the bounded operator B.",
        "keywords": [
            "C0-semigroup",
            "spectral bound s(A)",
            "growth bound"
        ],
        "authors": [
            {
                "name": "YANG Wei",
                "org": "School of Mathematical Sciences,Shanxi University,Taiyuan ,China"
            }
        ],
        "venue": "Journal of Taiyuan University of Science and Technology",
        "year": 2007
    },
    "AawtjwHH": {
        "id": "AawtjwHH",
        "title": "The Simultaneous Approximate Controllability and Observability of Riesz-spectral Systems",
        "abstract": "In this paper,we study the simultaneous approximate controllability and observability on infinite-time interval of the two Riesx-spectral systems Σ(Ai,Bi,Ci) on Hilbert space Xi:{z.(t)=Aizi(t)+Biu(t),zi(0)=zi0yi(t)=Cizi(t)i=1,2which have finite-rank inputs and outputs.In this case,by the use of matrix rank,we get the suffcient and necessary conditions to justify the sumultaneous approximate controllability and observability.",
        "keywords": [
            "simultaneous approximate controllability",
            "simultaneous approximate observability",
            "riesx-spectral system"
        ],
        "authors": [
            {
                "name": "SUN Li-qun",
                "org": "Taiyuan city vocational school,Taiyuam ,China"
            },
            {
                "name": "YANG Wei",
                "org": "Shanxi University School of Mathematical Science,Taiyuan ,China"
            }
        ],
        "venue": "Journal of Taiyuan University of Science and Technology",
        "year": 2007
    },
    "yzwTrdjq": {
        "id": "yzwTrdjq",
        "title": "SIMULTANEOUS APPROXIMATE CONTROLLABILITY OF DOUBLE SYSTEMS WITH A COMMON INPUT FUNCTION",
        "abstract": "This paper is concerned with the approximate controllability of two systems by means of a common input function.In the paper,the two systems are considered to be infinite-dimensional and one of them to be a Riesz-Spectral system.In this case,it is shown that if both systems are exactly controllable in time T_0 and the system generators have no common eigenvalues,then they are simultaneously approximately controllable in any time T>T_0.In addition,for special control operators,if one system(A_1,B_1) is approximately controllable and the other(A_2,A_2) is exactly controllable in time T_0,and the spectral sets of the two system generators satisfy the conditionσ(A_2)ρ_∞(A_1),then they are simultaneously approximately controllable in some time T>0.Finally,some applications of the obtained results are given and it is proved that the time at which the systems are simultaneously approximately controllable is optimal.",
        "keywords": [
            "simultaneous approximate controllability",
            "Riesz-Spectral operator",
            "Linear system"
        ],
        "authors": [
            {
                "name": "YANG Wei",
                "org": "School of Mathematical Science,Shanxi University,Taiyuan "
            },
            {
                "name": "LI Shengjia",
                "org": "School of Mathematical Science,Shanxi University,Taiyuan "
            }
        ],
        "venue": "Journal of Systems Science and Mathematical Sciences",
        "year": 2010
    },
    "pg7vh6bI": {
        "id": "pg7vh6bI",
        "title": "Sufficient Conditions for Simultaneous Approximate Observability of Two Exponentially Stable Systems",
        "abstract": "By using the spectral theory of the generator of exponentially stable semigroup,the sufficient conditions for simultaneous approximate observability in [0,∞)of the following two exponentially stable systems are obtained.1(t)=A1z1(t),z1(0)=x1,y1(t)=C1z1(t)2(t)=A2z2(t),z2(0)=x2,y2(t)=C2z2(t)",
        "keywords": [
            "simultaneous exact observability",
            "exponentially stable",
            "linear system"
        ],
        "authors": [
            {
                "name": "YANG Wei",
                "org": "School of Mathematical Sciences,Shanxi University,Taiyuan ,China"
            },
            {
                "name": "LI Sheng-jia",
                "org": "School of Mathematical Sciences,Shanxi University,Taiyuan ,China"
            }
        ],
        "venue": "Journal of Shanxi University(Natural Science Edition)",
        "year": 2010
    },
    "okhHiFif": {
        "id": "okhHiFif",
        "title": "Sufficient Conditions for Judging Simultaneous Exact Observability of a Class of Two Systems",
        "abstract": "By using of Hautus conditons for exact observability with a skew-adjoint generator,we obtain the sufficient conditons for simultaneous exact observability of the following two systems.1(t)=A1z1(t),z1(0)=z1,y1(t)=C1z1(t),2(t)=A2z2(t),z2(0)=z2,y2(t)=C2z2(t).",
        "keywords": [
            "simultaneous exact observability",
            "linear system",
            "Hautus conditions"
        ],
        "authors": [
            {
                "name": "YANG Wei",
                "org": "School of Mathematical Science,Shanxi University,Taiyuan ,China"
            },
            {
                "name": "LI Sheng-jia",
                "org": "School of Mathematical Science,Shanxi University,Taiyuan ,China"
            }
        ],
        "venue": "Journal of Shanxi University(Natural Science Edition)",
        "year": 2010
    },
    "hzl0BanT": {
        "id": "hzl0BanT",
        "title": "Test for Financial Market Stability Based on Quantile Regression Method",
        "abstract": "Based on the angles of the volatility,this paper gives a definition of financial market stability,proposes the test based on quantile regression method,and then tests the stability of Shanghai Market using the method.The empirical results show that the Shanghai stock market developed from unstable to stable,and particularly after the global financial crisis triggered by the U.S.subprime mortgage crisis,it has entered a stable state in relatively fast manner.The test method performs robust to the selections of systematic shock and periods of volatility.Meanwhile,the change of stock market stability indicate that a good range of policies for global financial crisis play a role in promoting a stable and healthy development of financial market.",
        "keywords": [
            "volatility",
            "quantile regression",
            "financial market stability"
        ],
        "authors": [
            {
                "name": "SHI Jin-feng",
                "org": "School of Management,Shanxi University,Taiyuan ,China"
            },
            {
                "name": "LIU wei-qi",
                "org": "School of Management,Shanxi University,Taiyuan ,China"
            },
            {
                "name": "YANG wei",
                "org": "School of Mathematical Science,Shanxi University,Taiyuan ,China"
            }
        ],
        "venue": "Chinese Journal of Management Science",
        "year": 2011
    },
    "TZ21pgb1": {
        "id": "TZ21pgb1",
        "title": "Automatic generation control strategy based on daily electric energy balance",
        "abstract": "Aiming at balance control difficulty,an AGC(Automatic Generation Control) strategy based on the balance of daily electric energy is put forward . After the power error,power charge percentage and speed weighting factor are set,the actual total generated energy controlled by automatic generation system is kept nearly equal to the planned total energy while the ACE(Area Control Error) is satisfied,as well as the actual 24-hour active power load curve to the planned one. The generated energy is corrected by velocity weighting factor to conduct dynamic regulation while the response speed is reached. Simulation is carried out with the practical operation data of Jiangsu power grid. Results show that the proposed strategy achieves the ACE regulation objective and realizes daily electric energy balance.",
        "keywords": [
            "ACE",
            "AGC",
            "Balance of daily electric energy",
            "Control strategy",
            "Power deviation",
            "Velocity weighting factor"
        ],
        "authors": [
            {
                "name": "WU Jun-ji",
                "org": "Nanjing University of Science & Technology,Nanjing ,China"
            },
            {
                "name": "SUN Qi",
                "org": "Nanjing University of Science & Technology,Nanjing ,China"
            },
            {
                "name": "YANG Wei",
                "org": "Nanjing University of Science & Technology,Nanjing ,China"
            }
        ],
        "venue": "Electric Power Automation Equipment",
        "year": 2006
    },
    "8FEMjX7w": {
        "id": "8FEMjX7w",
        "title": "Fusion of Gray Model Load Forecasting Based on Dempster Synthesize Rule of Evidential Theory",
        "abstract": "The gray model used in load forecasting is built up,and the gray model is used,which has three kinds of different ranks to estimate the load.According to that gray models estimate existed bigger error and change violently,evidential theory is put forward to carry fusion on errors of forecasting results.Through analyzing the estimated error of three kinds of gray model,Dempster synthesize rule is used to make fusion on error of forecasting results and the results are used again in load forecasting.The results demonstrate that the result has higher estimate accuracy after the fusion through Dempster synthesize rule of evidential theory.",
        "keywords": [
            "evidential theory",
            "gray model",
            "load forecasting",
            "Dempster synthesize rule"
        ],
        "authors": [
            {
                "name": "SUN Qi",
                "org": "Nanjing University of Science & technology,Nanjing ,China"
            },
            {
                "name": "YANG Wei",
                "org": "Nanjing University of Science & technology,Nanjing ,China"
            }
        ],
        "venue": "Electric Power Science and Engineering",
        "year": 2006
    },
    "jVWXHaGY": {
        "id": "jVWXHaGY",
        "title": "Mid-Long Term Load Forecasting of Power System Based on Double Extension Gather-Type Model",
        "abstract": "Aiming at thesituation that the load forecasting of power system mais have certain errors,double extension gather-type model and calculating way are put forward.Firstly,on the bass of constructing the classic area and stanza area,combining data-gather theory,samples are divided to several types according to the data of samples to be predicted.Then homologous connection-function is built up and each connection degree of category is got by calculation,and the category which belongs to samples to be estimated is decided. Then the double category is divided again according to the corresponding category,and higher accurate results are got.The results of load forecasting demonstrate that the double extension gather-type model hase higher estimation accuracy.",
        "keywords": [
            "matter-element model",
            "load forecasting",
            "double extension gather-type"
        ],
        "authors": [
            {
                "name": "SUN Qi",
                "org": "Department of Power Engineering Nanjing University of Science & Technology,Nanjing ,China"
            },
            {
                "name": "YANG Wei",
                "org": "Department of Power Engineering Nanjing University of Science & Technology,Nanjing ,China"
            }
        ],
        "venue": "Journal of Electric Power",
        "year": 2006
    },
    "PyhCefFk": {
        "id": "PyhCefFk",
        "title": "Simulation on Judgment of Autoreclosure Based on Natural Vibration Voltage Comparison",
        "abstract": "Judgment of automatic three-phase reclosure based on natural vibration voltage comparison is put forward in this paper,according to the present fuzzy judgment and fault operation in the process of reclosure.The judgment can distinct exactly the suspend fault or permanent fault through analyzing the natural vibration voltage caused by residual energy attenuation and so that it makes sure that the reclosure operates correctly.The simulation analysis of all kinds of short circuits is simulated in this paper and the judgment is demonstrated perfectly.",
        "keywords": [
            "natural vibration voltage",
            "autoreclosure",
            "simulation of short circuit"
        ],
        "authors": [
            {
                "name": "SUN Qi",
                "org": "College of Power Engineering,Nanjing University of Science & technology,Nanjing ,China"
            },
            {
                "name": "YANG Wei",
                "org": "College of Power Engineering,Nanjing University of Science & technology,Nanjing ,China"
            }
        ],
        "venue": "Journal of Electric Power",
        "year": 2007
    },
    "MJo0rdxM": {
        "id": "MJo0rdxM",
        "title": "Application of Gap Statistic in Identifying Bad Data of Power Systems",
        "abstract": "The technology of data mining based on clustering-algorithm gap statistic was applied to the identification of bad data in power systems.By comparing the logarithm of Euclidean square distances around means clustering with mathematical expectation of corresponding reference values,the optimal number of clusters was accordingly determined.The simulation results indicated that gap statistic is superior to traditional state estimation as to preventing residual contamination and misidentification.",
        "keywords": [
            "data mining",
            "identification of bad data",
            "gap statistic",
            "cluster analysis"
        ],
        "authors": [
            {
                "name": "WU Jing-qiu",
                "org": "Experiment and Training Center for Engineering Fundamentals,Nanjing Institute of Technology,Nanjing ,China"
            },
            {
                "name": "YANG Wei",
                "org": "School of Power Engineering,Nanjing University of Science & Technology,Nanjing ,China"
            }
        ],
        "venue": "Journal of Nanjing Institute of Technology(Natural Science Edition)",
        "year": 2007
    },
    "J0wC4Htr": {
        "id": "J0wC4Htr",
        "title": "Three Phase Adaptive Reclosure Based on Fuzzy Neural Network",
        "abstract": "Fuzzy neural network is used in the three phase adaptive reclosure so that the reclose of permanent faults can be avoided.A multi-input fuzzy neural network is constructed and the algorithm of network is designed.Taking the virtual value of three phase voltage as the input with its scale changed,the network learning can be completed with convergence reached after the process of fuzzification,normalization and perspicuity,so it can disinguish transient faults from permanent faults.The learning specimen of the fuzzy neural network is fetched from model simulation,and the accuracy of the algorithm is testified by the MATLAB simulation results.",
        "keywords": [
            "fuzzy neural network",
            "transient faults",
            "parmanent faults",
            "three phase adaptive reclosure"
        ],
        "authors": [
            {
                "name": "YANG Wei",
                "org": "College of Power Engineering,Nanjing University of Science andTechnology,Nanjing ,China"
            },
            {
                "name": "SUN Qi",
                "org": "College of Power Engineering,Nanjing University of Science andTechnology,Nanjing ,China"
            }
        ],
        "venue": "Proceedings of the Chinese Society of Universities for Electric Power System and Automation",
        "year": 2007
    },
    "t1AkQJKj": {
        "id": "t1AkQJKj",
        "title": "Emergency Control Scheme of Power System Based on Agent",
        "abstract": "Based on the thinking of centralized management and partitioning control, a multi-agent system (MAS) based synergicable power system emergency control scheme is proposed. When power system is in case of emergency, in the controlled area the Lord Agents, which are used to deal with critical failure, compose an MAS and under the action coordination by rule of contract network an emergency control measure is rapidly formed and transmitted to agents in all emergency control regions, thus the critical failure is dealt with in parallel. To validate the superiority of above-mentioned control scheme, simulation is performed in WSCC 4-machine system. Simulation results show that for critical failures occurred in different places this control scheme can rapidly draft control measures and quickly transmit the control instructions to Lord Agents in all control regions, so the time for allocating and executing the emergency control measures can be extremely shortened.",
        "keywords": [
            "emergency control",
            "multi-agent system",
            "power system",
            "the contract network",
            "agent"
        ],
        "authors": [
            {
                "name": "YANG Wei",
                "org": "College of Power Engineering,Nanjing University of Science & Technology,Nanjing ,Jiangsu Province,China"
            },
            {
                "name": "HU Jun",
                "org": "College of Power Engineering,Nanjing University of Science & Technology,Nanjing ,Jiangsu Province,China"
            },
            {
                "name": "ZHANG Jun-fang",
                "org": "College of Power Engineering,Nanjing University of Science & Technology,Nanjing ,Jiangsu Province,China"
            },
            {
                "name": "WU Jun-ji",
                "org": "College of Power Engineering,Nanjing University of Science & Technology,Nanjing ,Jiangsu Province,China"
            }
        ],
        "venue": "Power System Technology",
        "year": 2007
    },
    "SxaEL2mW": {
        "id": "SxaEL2mW",
        "title": "A New Restraint Technique of Transformer Inrush Current",
        "abstract": "A new restraint technique of transformer inrush current is proposed based on studying the generation mechanism and influence factors of transformer inrush current and comparing the advantage and disadvantage of technologies existed now.Considering the influence of residual flux and applying controlled closing technology,transformer inrush current is reduced by combing controlled closing technology and series resistance,setting proper resistance and cut time.The simulation results show that the technology could reduce the closing inrush current of transformer effectively.",
        "keywords": [
            "controlled closing technology",
            "transformer inrush current",
            "series resistance"
        ],
        "authors": [
            {
                "name": "PENG Jing-ping",
                "org": "School of Power Engineering,NUST,Nanjing ,China"
            },
            {
                "name": "ZHANG Jun-fang",
                "org": "School of Power Engineering,NUST,Nanjing ,China"
            },
            {
                "name": "YANG Wei",
                "org": "School of Power Engineering,NUST,Nanjing ,China"
            }
        ],
        "venue": "Journal of Hohai University Changzhou",
        "year": 2007
    },
    "jRnKxUIk": {
        "id": "jRnKxUIk",
        "title": "The Correction of the Bad Data in Power System Based on Neural Network",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "YE Xue-yong",
                "org": "School of Power Engineering,Nanjing University of Science and Technology,Nanjing ,Jiangsu Province,China"
            },
            {
                "name": "WU Jun-ji",
                "org": "School of Power Engineering,Nanjing University of Science and Technology,Nanjing ,Jiangsu Province,China"
            },
            {
                "name": "YANG Wei",
                "org": "School of Power Engineering,Nanjing University of Science and Technology,Nanjing ,Jiangsu Province,China"
            },
            {
                "name": "ZHANG Jun-fang",
                "org": "School of Power Engineering,Nanjing University of Science and Technology,Nanjing ,Jiangsu Province,China"
            }
        ],
        "venue": "Power System Technology",
        "year": 2007
    },
    "hLUhARng": {
        "id": "hLUhARng",
        "title": "Application of New Intelligent Algorithm to Reactive Power Optimization",
        "abstract": "To overcome the shortcomings of the dynamic reactive power optimization model,a new intelligent algorithm combined with ant colony algorithm and immune algorithm is suggested for its optimization.The advantages of these two algorithms are used to compensate for each other.The ant colony algorithm is used as antibody to generate values for parameters through the immune Algorithm.Through series of operations of crossing,mutation and affinity degree selecting,the strong antibodies are conserved and the weak ones are removed.The risk of being trapped into local minimums from the single heuristic mechanism is reduced.The fault of complicated boundary constraint is corrected by adopting a new method to cope with boundary constraint condition.Its application to the 69 nodes power supply network shows the effectiveness of the method.",
        "keywords": [
            "dynamic reactive power optimization",
            "ant colony algorithm",
            "immune algorithm",
            "intelligent algorithm",
            "power system"
        ],
        "authors": [
            {
                "name": "Bao Yidong",
                "org": "School of Power Engineering,Nanjing University of Science and Technology,Nanjing ,China"
            },
            {
                "name": "Yang Wei",
                "org": "School of Power Engineering,Nanjing University of Science and Technology,Nanjing ,China"
            }
        ],
        "venue": "Modern Electric Power",
        "year": 2007
    },
    "chZAuebc": {
        "id": "chZAuebc",
        "title": "Short-term Load Forecasting of Neural Network on Dempster Rule of Evidential Theory",
        "abstract": "Aiming that the traditional neural network has slow concentration speed and weak follow-time function, The distance changed BP network, RBF network and Elman network calculating ways are used in load forecasting at an area, according to the situation of weather factor. By analyzing the error of load forecasting, calculating ways have fusion through Dempster fusion rule of evidential theories. Through choosing the data of several days before estimated day as fusion samples and ruling the homologous basic belief degree function, belief degree allotment is fetched after the fusion.The load forecasting model is decided according to the corresponding time.The results of simulation demonstrate that the load forecasting calculating ways after fusion of evidential theories have higher accuracy.",
        "keywords": [
            "evidential theory",
            "neural network",
            "load forecasting",
            "Dempster synthesize rule"
        ],
        "authors": [
            {
                "name": "SUN Qi",
                "org": "College of Power Engineering, Nanjing University of Science & Technology, Nanjing , China"
            },
            {
                "name": "YANG Wei",
                "org": "College of Power Engineering, Nanjing University of Science & Technology, Nanjing , China"
            }
        ],
        "venue": "Central China Electric Power",
        "year": 2007
    },
    "3V03lPJL": {
        "id": "3V03lPJL",
        "title": "Research on load forecasting of fusion between D-S evidential theory improved BP network",
        "abstract": "Aiming at the shortcomings of the traditional BP network,three kinds of changed BP network calculating ways are used in load forecasting at an area,according to the situation of weather factor.By analyzing the error of load forecasting,calculating ways have fusion through Dempster fusion rule of evidential theories.Through choosing the data of several days before estimated day as fusion samples and ruling the homologous basic belief degree function,belief degree allotment is fetched after the fusion.The load forecasting model is decided according to the corresponding time.The results of simulation demonstrate that the load forecasting calculating ways after fusion of evidential theories have higher accuracy.",
        "keywords": [
            "evidential theory",
            "improved BP network",
            "load forecasting",
            "Dempster synthesize rule"
        ],
        "authors": [
            {
                "name": "SUN Qi",
                "org": "College of Power Engineering,Nanjing University of Science & Technology,Nanjing ,China"
            },
            {
                "name": "YANG Wei",
                "org": "College of Power Engineering,Nanjing University of Science & Technology,Nanjing ,China"
            }
        ],
        "venue": "Relay",
        "year": 2007
    },
    "m3SfCXu1": {
        "id": "m3SfCXu1",
        "title": "Short-term Load Forecasting Based on Dual Part-return Elman Neural Network",
        "abstract": "Aiming at the weakness of traditional static forward feedback neural network in dynamic performance,the dual part-return Elman neural network is put forward.The basic structure of the network is built up,and homologous study algorithm and learning process are designed.Through returning the original data of load to one,the thought of dividing training data to segments is put forward,and data of segment is used for training the dual part-return Elman network.Suitable amount of neural and training period of network are decided through analyzing concentration curve and training error.And the network examination is carried by using actual load data finally.The results demonstrate that the changed dual part-return Elman neural network has higher estimating accuracy than traditional Elman neural network.",
        "keywords": [
            "short-term load forecasting",
            "Elman neural network",
            "concentration curve",
            "dual part-return"
        ],
        "authors": [
            {
                "name": "SUN Qi",
                "org": "Nanjing University of Science & Technology,Nanjing ,China"
            },
            {
                "name": "YANG Wei",
                "org": "Nanjing University of Science & Technology,Nanjing ,China"
            }
        ],
        "venue": "Jiangsu Electrical Engineering",
        "year": 2007
    },
    "SEwOv2Py": {
        "id": "SEwOv2Py",
        "title": "Research of auto-adaptive current protection simulation",
        "abstract": "The traditional current protection is easily effected by the running conditions and fault pattern across to its principle,while the auto-adaptive current protection can overcome these defects.The principle of auto-adaptive current protection is described,and the protection performace is analyzed.In use of ATP-EMTP,the faults of 35kV power line is simulated,compared with the traditional type,the simulation results indicate that the auto-adaptive electric current protection surpasses the traditional type in the protection performance.",
        "keywords": [
            "auto-adaptive",
            "protection performance",
            "running conditions",
            "fault pattern"
        ],
        "authors": [
            {
                "name": "KONG Fan-fang",
                "org": "School of Power Engineering,Nanjing University of Science and Technology,Nanjing ,China"
            },
            {
                "name": "WU Jun-ji",
                "org": "School of Power Engineering,Nanjing University of Science and Technology,Nanjing ,China"
            },
            {
                "name": "YE Xue-yong",
                "org": "School of Power Engineering,Nanjing University of Science and Technology,Nanjing ,China"
            },
            {
                "name": "YANG Wei",
                "org": "School of Power Engineering,Nanjing University of Science and Technology,Nanjing ,China"
            },
            {
                "name": "ZHANG Jun-fang",
                "org": "School of Power Engineering,Nanjing University of Science and Technology,Nanjing ,China"
            }
        ],
        "venue": "Relay",
        "year": 2008
    },
    "5t38DyyM": {
        "id": "5t38DyyM",
        "title": "Research on Reactive Power Optimization Control of Electric Power System Based on Multi-Agent System",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "ZHANG Xiao-lian",
                "org": "College of Power Engineering,Nanjing University of Science & Technology,Nanjing ,Jiangsu Province,China"
            },
            {
                "name": "YANG Wei",
                "org": "College of Power Engineering,Nanjing University of Science & Technology,Nanjing ,Jiangsu Province,China"
            }
        ],
        "venue": "Power System Technology",
        "year": 2008
    },
    "hsH16FMH": {
        "id": "hsH16FMH",
        "title": "Study on current fast tripping adaptive protection based on multi-agent technology",
        "abstract": "Modern power system is a complex,open and distributed system.Multi-agent is a new technology of distributed artificial intelligence.In this paper,the multi-agent theory is applied in the adaptive protection,and the architecture of MAS is built in it.Through the cooperation among agents,the adaptive protection can adapt protection to various changes of power system automatically and intelligently.To achieve adaptive current fast tripping protection,this paper defines each agent function and designs the communication mechanism between them by the Agent’s design principle.To prove its feasibility,a simulation is made on a simple system.The results of the simulation validate that MAS-based adaptive current fast tripping protection can not only expand the scope of protection,but also shorten the backup protection action time.",
        "keywords": [
            "action time",
            "multi-agent system",
            "adaptive protection",
            "current fast tripping",
            "protection scope"
        ],
        "authors": [
            {
                "name": "YANG Wei",
                "org": "College of Power Engineering,Nanjing University of Science & Technology,Nanjing ,China"
            },
            {
                "name": "HUA Liang",
                "org": "College of Power Engineering,Nanjing University of Science & Technology,Nanjing ,China"
            }
        ],
        "venue": "Relay",
        "year": 2008
    },
    "qaKho1iQ": {
        "id": "qaKho1iQ",
        "title": "Research on Fault Diagnosis System for Hydroelectric Generating Sets Based on MAS",
        "abstract": "The paper embarks from the present situation of intelligent diagnosis technology, taking malfunction diagnosis for hydroelectric generating sets as the research object, taking the MAS theory as the foundation and proposes special diagnosis for MAS. In view of the limitation of present fault diagnosis system for hydroelectric sets and the singleness of method, the paper brings the new hydroelectric sets fault diagnosis system based on MAS. The paper has studied the hydroelectric generating sets fault diagnosis strategy based on agent. The fuzzy algorithm is used for analyzing the diagnosis task in system agent. The neural network is used for exact analyzing the fault type in diagnosis agent. Finally, the paper take the simulated example about the fault which will occurs to electrical machinery through the reality calculated. The simulation result indicated the fault decomposition as well as malfunction diagnosis for agent can complete the system analysis, which conformed to the precision requirement of system diagnosis.",
        "keywords": [
            "fault diagnosis",
            "intelligent agent",
            "Multi-agent System (MAS)",
            "neural network",
            "knowledge representation",
            "fuzzy algorithm",
            "hydroelectric generating sets"
        ],
        "authors": [
            {
                "name": "Yang Wei",
                "org": "School of Power Engineering, Nanjing University of Science and Technology, Nanjing , China"
            },
            {
                "name": "Bao Sijia",
                "org": "School of Power Engineering, Nanjing University of Science and Technology, Nanjing , China"
            }
        ],
        "venue": "Electric Power Science and Engineering",
        "year": 2008
    },
    "3nvIf2Bg": {
        "id": "3nvIf2Bg",
        "title": "Study on Earth Fault Detection in Small Current Grounding Network Based on Evidence Theory",
        "abstract": "Aiming at the disadvantages of single detection methods of earth fault,the method of earth fault detection in small current grounding network based on evidence theory was put forward.Six typical fault cases were simulated and the fault measures of each line in all kinds of fault cases were found.The simulated result indicated that the method of earth fault detection in small current grounding network based on evidence theory could detect the fault line correctl.The method could be used widely and had good reliability.",
        "keywords": [
            "evidence theory",
            "fault measure",
            "detection criterions",
            "earth fault detection"
        ],
        "authors": [
            {
                "name": "YANG Wei",
                "org": "College of Power Engineering,Nanjing University of Science & Technology,Nanjing ,China"
            },
            {
                "name": "GU Mingxing",
                "org": "College of Power Engineering,Nanjing University of Science & Technology,Nanjing ,China"
            },
            {
                "name": "PENG Jingping",
                "org": "College of Power Engineering,Nanjing University of Science & Technology,Nanjing ,China"
            }
        ],
        "venue": "Low Voltage Apparatus",
        "year": 2009
    },
    "shpq8OR5": {
        "id": "shpq8OR5",
        "title": "Short-term load forecast model fusion based on D-S evidence theory",
        "abstract": "The determination of weights in forecast model fusion affects greatly the forecast precision.The weight extraction model and weight fusion model are established respectively for three neural network load forecast models and fused by using evidence theory.The fusion samples of evidence theory are extracted based on the analysis of historical forecasts and the multi-fusion result of belief function is taken as the weight of load forecast model,by which the day load is forecasted.The load forecasted is compared with those by other independent models,which demonstrates that the model with weight fusion has higher forecast precision.",
        "keywords": [
            "weight",
            "neural network",
            "synthesis rule",
            "D-S evidence theory",
            "load forecast"
        ],
        "authors": [
            {
                "name": "WU Jingqiu",
                "org": "Nanjing Institute of Technology,Nanjing ,China"
            },
            {
                "name": "SUN Qi",
                "org": "College of Power Engineering,Nanjing University of Science & Technology,Nanjing ,China"
            },
            {
                "name": "YANG Wei",
                "org": "College of Power Engineering,Nanjing University of Science & Technology,Nanjing ,China"
            },
            {
                "name": "YANG Jie",
                "org": "General Affair Department,Nanjing University of Science & Technology,Nanjing ,China"
            }
        ],
        "venue": "Electric Power Automation Equipment",
        "year": 2009
    },
    "tEiY2eiY": {
        "id": "tEiY2eiY",
        "title": "Coordinated Control of Excitation and SVC in Multi-machine Power System Based on the Fuzzy Control",
        "abstract": "The transient stability of a long transmission system can be significantly influenced by the action of excitation system and SVC. The SVC and excitation controls for generator are proposed to make rotor angle and voltage stable by the fuzzy control. The method is based on the fuzzy set theory,fuzzy language variable and fuzzy logic inference. It can convert coordinated control strategy of excitation and SVC into the fuzzy rule,and realizing the fuzzy control of multi-machine power system. The numerical simulation,which is resulted from three-machine example system,shows clearly that the fuzzy control based on the input variables of Δω and Δω has better transient stability under different situations of fault when compared with AVR/PSS excitation controller and PID SVC controller. It is also proved to be effective in damping the oscillations and enhancing the system voltage stability.",
        "keywords": [
            "multi-machine power system",
            "SVC",
            "numerical integration",
            "transient stability",
            "simulation",
            "fuzzy control"
        ],
        "authors": [
            {
                "name": "Zhao Hu",
                "org": "School of Power Engineering,Nanjing University of Science and Technology,Nanjing "
            },
            {
                "name": "Yang Wei",
                "org": "School of Power Engineering,Nanjing University of Science and Technology,Nanjing "
            },
            {
                "name": "Zhao Meng",
                "org": " Ganyu Power Supply Company,Lianyungang,Jiangsu "
            }
        ],
        "venue": "Electrical Engineering",
        "year": 2010
    },
    "qNULK3iG": {
        "id": "qNULK3iG",
        "title": "Coordinated Control of Excitation and STATCOM in Multi-machine Power Systems",
        "abstract": "Because the traditional way has weaknesses in keeping node voltage,controlling the damping system oscillations and enhancing the transient behavior of the power system,the STATCOM and excitation coordinated controls for generators are proposed based on the fuzzy control.The proposed method is based on the fuzzy set theory,fuzzy language variable and fuzzy logic inference to convert the coordinated control strategy of excitation and STATCOM into the fuzzy rule,realizing the stability control of the multi-machine power system.The numerical simulation on three-machine example system shows that the coordinated control has better dynamic feature and owns stronger robustness under different situations of fault when compared with AVR/PSS excitation controller and PID STATCOM controller.It is also proved to be effective in enhancing the system voltage stability.",
        "keywords": [
            "coordinated control",
            "multi-machine power system",
            "transient stability",
            "STATCOM",
            "numerical simulation",
            "fuzzy control"
        ],
        "authors": [
            {
                "name": "YANG Wei",
                "org": "School of Power Engineering,Nanjing University of Science and Technology,Nanjing ,China"
            },
            {
                "name": "ZHAO Hu",
                "org": "School of Power Engineering,Nanjing University of Science and Technology,Nanjing ,China"
            },
            {
                "name": "LI Lei",
                "org": "School of Power Engineering,Nanjing University of Science and Technology,Nanjing ,China"
            },
            {
                "name": "ZHAO Meng",
                "org": "Ganyu Power Supply Company,Lianyungang ,China"
            }
        ],
        "venue": "Control Engineering of China",
        "year": 2010
    },
    "E455nQxD": {
        "id": "E455nQxD",
        "title": "Secondary Voltage Control Based on Bacterial Colony Chemotaxis Algorithm",
        "abstract": "It is the crucial procedure for hierarchical voltage control to solve the strategy for secondary voltage control. For the feature that control devices perform continuous regulation and discrete regulation,a mathematical model of improved discrete secondary voltage control system is built,in which the discrete regulation devices such as transformer fitted with on-load tap changer (OLTC) and so on are included,meanwhile to make the proposed model more confirm to the condition of actual power system both the impact among secondary voltage control regions and the terminal voltage deviations of reactive power compensation devices are taken into account. Besides,a new colony intelligent optimization algorithm,namely the bacterial colony chemotaxis (BCC),is applied to solve the proposed model. In the environment of Matlab,the proposed model is simulated by New England 39-bus system and the results show that comparing with traditional secondary voltage control strategies,the secondary voltage control effect is evidently improved while the discrete control devices such as transformer fitted with OTLC and so on are added. The BCC algorithm can deal with the problems with discrete variables as well and possesses such advantages as fast converge speed,high accuracy and fewer resource occupation.",
        "keywords": [
            "on-load tap changer (OLTC)",
            "bacterial colony chemotaxis algorithm",
            "secondary voltage control",
            "control strategy"
        ],
        "authors": [
            {
                "name": "HUA Liang",
                "org": "College of Power Engineering,Nanjing University of Science and Technology,Nanjing ,Jiangsu Province,China"
            },
            {
                "name": "YANG Wei",
                "org": "College of Power Engineering,Nanjing University of Science and Technology,Nanjing ,Jiangsu Province,China"
            }
        ],
        "venue": "Power System Technology",
        "year": 2010
    },
    "Pf4lnANp": {
        "id": "Pf4lnANp",
        "title": "Application of evidence theory in fault diagnosis for electric machine",
        "abstract": "D-S evidence theory has its own unique advantages as an inaccurate reasoning means, and it's in point of fault diagnosis for electric machine having large inexact factors. Firstly, the state features of fault electric machine are extracted and decomposed into a number of sub-spaces according to time domain, frequency domain and singular value. On the basis, partial diagnosis is realized based on BP neural networks and fuzzy cluster systems. The independent evidences can be obtained using the results of partial diagnosis, and the belief assignment function of corresponding evidence is constructed. To diagnose the states of electric machine by fusing some evidences' information, this paper combines information fusion model of fault electric machine and makes decision based on D-S evidence theory. The testing results show that the application of D-S evidences can improve the accuracy and delicacy of fault diagnosis.",
        "keywords": [
            "BP neural network",
            "D-S evidence theory",
            "Fault diagnosis for electric machine",
            "Fuzzy cluster analysis"
        ],
        "authors": [
            {
                "name": "Wei Yang",
                "org": "Nanjing University of Science and Technology(Nanjing University of Science and Technology,Nanjing Univ. of Sci. and Technol.,Nanjing Univ. of Sci. and Technology,NUST),Nanjing,China"
            },
            {
                "name": "Ming Xing Gu",
                "org": "Nanjing University of Science and Technology(Nanjing University of Science and Technology,Nanjing Univ. of Sci. and Technol.,Nanjing Univ. of Sci. and Technology,NUST),Nanjing,China"
            },
            {
                "name": "Jing Ping Peng",
                "org": "Nanjing University of Science and Technology(Nanjing University of Science and Technology,Nanjing Univ. of Sci. and Technol.,Nanjing Univ. of Sci. and Technology,NUST),Nanjing,China"
            }
        ],
        "venue": "Dianli Xitong Baohu yu Kongzhi/Power System Protection and Control",
        "year": 2010
    },
    "fygxzv6S": {
        "id": "fygxzv6S",
        "title": "Design of Coordinated Controller of Generators' Excitation and Valve",
        "abstract": "The coordinated control of generator's excitation and valve is effective and fast way to promote the power system stability.This paper designs a kind of coordinated controller of generator's excitation and valve that is based on the fuzzy neural networks.The controller can combine the fuzzy theory and artificial neural networks organically,which is applicable to multilayer feedforward BP network and fuzzy inference control model.The self-learning network can modify weights to realize the self-learning control of fuzzy neural networks.Throngh the simulation of the single machine infinite bus system(SMIBS),the results show the controller has better stability and dynamic feature based on the fuzzy neural networks and stronger robustness under different situations of fault.",
        "keywords": [
            "stability",
            "coordinated controller of generator's excitation and valve",
            "power system",
            "fuzzy neural networks",
            "simulation"
        ],
        "authors": [
            {
                "name": "YANG Wei",
                "org": "School of Power Engineering,Nanjing University of Science and Technology,Nanjing ,China"
            },
            {
                "name": "ZHAO Hu",
                "org": "School of Power Engineering,Nanjing University of Science and Technology,Nanjing ,China"
            },
            {
                "name": "LIU Jun",
                "org": "School of Power Engineering,Nanjing University of Science and Technology,Nanjing ,China"
            }
        ],
        "venue": "Proceedings of the Chinese Society of Universities for Electric Power System and its Automation",
        "year": 2010
    },
    "Er1gM4oQ": {
        "id": "Er1gM4oQ",
        "title": "Research on the control strategy to connect fuel cells with power grid",
        "abstract": "Because the traditional control method about connecting fuel cells with the power grid has the disadvantage of slow dynamic response, this paper constructs the model of DC/DC boost converter and inverter in PEMFC (Proton Exchange Membrane Fuel Cell) power generating system, and offers a new control strategy to control fuel cells system with power grid. The double closed-loop control method is adopted, which makes the output of the inverter meet the requirement of the system. The paper also builds the model of simulation system, and the handling of the fuel cells nodes in network equation is also given. The numerical simulation of the system in the conditions of three-phase short-circuit fault, voltage dip and mutational load proved under certain faults, such control strategy can run the fuel cells system steadily, as well as track the dynamic output of the system smoothly.",
        "keywords": [
            "Control strategy with power grid",
            "Fuel cells",
            "Numerical simulation",
            "System steady",
            "Three-phase short circuit"
        ],
        "authors": [
            {
                "name": "Wei Yang",
                "org": "Nanjing University of Science and Technology(Nanjing University of Science and Technology,Nanjing Univ. of Sci. and Technol.,Nanjing Univ. of Sci. and Technology,NUST),Nanjing,China"
            },
            {
                "name": "Hong Lin",
                "org": "Nanjing University of Science and Technology(Nanjing University of Science and Technology,Nanjing Univ. of Sci. and Technol.,Nanjing Univ. of Sci. and Technology,NUST),Nanjing,China"
            },
            {
                "name": "Hu Zhao",
                "org": "Nanjing University of Science and Technology(Nanjing University of Science and Technology,Nanjing Univ. of Sci. and Technol.,Nanjing Univ. of Sci. and Technology,NUST),Nanjing,China"
            }
        ],
        "venue": "Dianli Xitong Baohu yu Kongzhi/Power System Protection and Control",
        "year": 2011
    },
    "pBPD5BaD": {
        "id": "pBPD5BaD",
        "title": "Hemoglobin variability and mortality in ESRD.",
        "abstract": "Hemoglobin levels vary substantially over time in hemodialysis patients, and this variability may portend poor outcomes. For a given patient, hemoglobin concentration over time can be described by absolute levels, rate of change, or by the difference between observed level and expected level based on the preceding trend (i.e., seemingly random variability). We investigated the independent associations of these different methods of describing hemoglobin over time with mortality in a retrospective cohort of 34,963 hemodialysis patients. Hemoglobin concentration over time was modeled with linear regression for each subject, and the model was then used to define the subject's absolute level of hemoglobin (intercept), temporal trend in hemoglobin (slope), and hemoglobin variability (residual standard deviation). Survival analyses indicated that each 1g/dl increase in the residual standard deviation was associated with a 33% increase in rate of death, even after adjusting for multiple covariates. Patient characteristics accounted for very little of the variation in our hemoglobin variability metric (R2 = 0.019). We conclude that greater hemoglobin variability is independently associated with higher mortality.",
        "keywords": [
            "rate of change",
            "random variable",
            "linear regression"
        ],
        "authors": [
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Rubeen K Israni",
                "org": ""
            },
            {
                "name": "Steven M Brunelli",
                "org": ""
            },
            {
                "name": "Marshall M Joffe",
                "org": ""
            },
            {
                "name": "Steven Fishbane",
                "org": ""
            },
            {
                "name": "Harold I Feldman",
                "org": ""
            }
        ],
        "venue": "Journal of the American Society of Nephrology : JASN",
        "year": 2007
    },
    "lxMMRsKE": {
        "id": "lxMMRsKE",
        "title": "Brain oxygen tension and outcome in patients with aneurysmal subarachnoid hemorrhage: Clinical article",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Rohan Ramakrishna",
                "org": ""
            },
            {
                "name": "Michael Stiefel",
                "org": ""
            },
            {
                "name": "Joshua Udoteuk",
                "org": ""
            },
            {
                "name": "Alejandro Spiotta",
                "org": ""
            },
            {
                "name": "Joshua M. Levine",
                "org": ""
            },
            {
                "name": "W. Andrew Kofke",
                "org": ""
            },
            {
                "name": "Eric Zager",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Peter LeRoux",
                "org": ""
            }
        ],
        "venue": "Journal of Neurosurgery",
        "year": 2008
    },
    "wNe0RE28": {
        "id": "wNe0RE28",
        "title": "History-adjusted marginal structural analysis of the association between hemoglobin variability and mortality among chronic hemodialysis patients.",
        "abstract": "Background and objectives: Hemoglobin variability is common among dialysis patients, and has been associated with increased mortality. The causal nature of this association has been difficult to ascertain because of potential time-dependent confounding, for which traditional statistical methods do not control. Design, settings, participants, & measurements: A retrospective cohort of 34,963 Fresenius Medical care dialysis patients from 1996 was assembled. Hemoglobin variability, absolute hemoglobin level, and temporal hemoglobin trend were mea- sured over rolling 6-mo exposure windows. Their association with mortality was estimated using history-adjusted marginal structural analysis that adjusts for time-dependent confounding by applying weights to observations inversely related to the predictability of observed levels of hemoglobin. Results: In the primary analysis, each g/dl increase in hemoglobin variability was associated with an adjusted hazard ratio (HR) (95% confidence interval (CI)) for all-cause mortality of 1.93 (1.20 to 3.10). Neither higher absolute hemoglobin level nor increasing hemoglobin trend were significantly associated with mortality; adjusted HR (95% CI) 0.85 (0.64 to 1.11) and 0.60 (0.25 to 1.45), respectively. Conclusions: Marginal structural analysis demonstrates that hemoglobin variability is associated with increased mortality among chronic hemodialysis patients, and that this effect is more pronounced than appreciated using standard statistical techniques that do not take time-dependent confounding into account.",
        "keywords": [],
        "authors": [
            {
                "name": "Steven M Brunelli",
                "org": "Renal, Electrolyte and Hypertension Division of the Department of Medicine, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA."
            },
            {
                "name": "Marshall M Joffe",
                "org": ""
            },
            {
                "name": "Rubeen K Israni",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Steven Fishbane",
                "org": ""
            },
            {
                "name": "Jeffrey S Berns",
                "org": ""
            },
            {
                "name": "Harold I Feldman",
                "org": ""
            }
        ],
        "venue": "Clinical journal of the American Society of Nephrology : CJASN",
        "year": 2008
    },
    "BTYKPGwv": {
        "id": "BTYKPGwv",
        "title": "Patient Reported Receipt of Medication Instructions for Warfarin is Associated with Reduced Risk of Serious Bleeding Events",
        "abstract": "Background  Adverse drug events are an important cause of preventable hospitalizations.\n \n \n \n Objective  To identify whether patient report of receipt of medication instructions and markers of complex care (multiple physicians,\n recent hospitalization) predict the risk of serious bleeding for older adults on warfarin.\n \n \n \n Design  Prospective cohort study of older adults.\n \n \n \n Participants  Subjects filled new or refill prescriptions for warfarin at the time of enrollment.\n \n \n \n Measurements  Hospitalizations were identified through a state-wide registry. Discharge summaries of hospitalizations for possible warfarin\n related bleeding events were reviewed by trained abstractors and clinical experts. Incidence rate ratios (IRR) were estimated\n based on person-months of exposure using Poisson regression models.\n \n \n \n Results  From March 2002 through May 2003, we enrolled a total of 2346 adults on warfarin. Over a two-year follow-up period, there\n were 126 hospitalizations due to warfarin-related bleeding (4.6 hospitalizations per 100 person-years of exposure). Patients\n who reported receiving medication instructions from either a physician or nurse plus a pharmacist had a 60% reduced rate of\n subsequently experiencing a serious bleeding event over the next 2 years (adjusted IRR 0.40, 95% CI 0.24–0.68). Having ≥4\n physicians providing medication prescriptions over the last 3 months and filling prescriptions at >1 pharmacy over the last\n 3 months were independently associated with increased bleeding rates (adjusted IRRs 2.37, 95% CI 1.22–4.57 and 1.61, 95% CI\n 0.97–2.67, respectively).\n \n \n \n Conclusions  The rate of warfarin-related hospitalization for bleeding is substantially lower for patients who report receiving medication\n instructions from a physician or nurse and a pharmacist.",
        "keywords": [
            "patient communication",
            "medication safety.",
            "anticoagulation",
            "prospective studies",
            "incidence rate ratio",
            "cohort study",
            "poisson regression model",
            "risk factors",
            "cohort studies"
        ],
        "authors": [
            {
                "name": "Joshua P. Metlay",
                "org": "University of Pennsylvania School of Medicine Center for Clinical Epidemiology & Biostatistics, Department of Biostatistics & Epidemiology Philadelphia PA USA"
            },
            {
                "name": "Sean Hennessy",
                "org": "University of Pennsylvania School of Medicine Center for Clinical Epidemiology & Biostatistics, Department of Biostatistics & Epidemiology Philadelphia PA USA"
            },
            {
                "name": "A. Russell Localio",
                "org": "University of Pennsylvania School of Medicine Center for Clinical Epidemiology & Biostatistics, Department of Biostatistics & Epidemiology Philadelphia PA USA"
            },
            {
                "name": "Xiaoyan Han",
                "org": "University of Pennsylvania School of Medicine Center for Clinical Epidemiology & Biostatistics, Department of Biostatistics & Epidemiology Philadelphia PA USA"
            },
            {
                "name": "Wei Yang",
                "org": "University of Pennsylvania School of Medicine Center for Clinical Epidemiology & Biostatistics, Department of Biostatistics & Epidemiology Philadelphia PA USA"
            },
            {
                "name": "Abigail Cohen",
                "org": "University of Pennsylvania School of Medicine Center for Clinical Epidemiology & Biostatistics, Department of Biostatistics & Epidemiology Philadelphia PA USA"
            },
            {
                "name": "Charles E. Leonard",
                "org": "University of Pennsylvania School of Medicine Center for Clinical Epidemiology & Biostatistics, Department of Biostatistics & Epidemiology Philadelphia PA USA"
            },
            {
                "name": "Kevin Haynes",
                "org": "University of Pennsylvania School of Medicine Center for Clinical Epidemiology & Biostatistics, Department of Biostatistics & Epidemiology Philadelphia PA USA"
            },
            {
                "name": "Stephen E. Kimmel",
                "org": "University of Pennsylvania School of Medicine Center for Clinical Epidemiology & Biostatistics, Department of Biostatistics & Epidemiology Philadelphia PA USA"
            },
            {
                "name": "Harold I. Feldman",
                "org": "University of Pennsylvania School of Medicine Center for Clinical Epidemiology & Biostatistics, Department of Biostatistics & Epidemiology Philadelphia PA USA"
            },
            {
                "name": "Brian L. Strom",
                "org": "University of Pennsylvania School of Medicine Center for Clinical Epidemiology & Biostatistics, Department of Biostatistics & Epidemiology Philadelphia PA USA"
            }
        ],
        "venue": "Journal of General Internal Medicine",
        "year": 2008
    },
    "czIMcejL": {
        "id": "czIMcejL",
        "title": "BRAIN HYPERTHERMIA AFTER TRAUMATIC BRAIN INJURY DOES NOT REDUCE BRAIN OXYGEN. Commentaries",
        "abstract": "",
        "keywords": [
            "oxygen",
            "treatment",
            "surgery",
            "temperature"
        ],
        "authors": [
            {
                "name": "alejandro m spiotta",
                "org": ""
            },
            {
                "name": "michael f stiefel",
                "org": ""
            },
            {
                "name": "gregory g heuer",
                "org": ""
            },
            {
                "name": "stephanie k bloom",
                "org": ""
            },
            {
                "name": "eileen maloneywilensky",
                "org": ""
            },
            {
                "name": "wei yang",
                "org": ""
            },
            {
                "name": "m sean grady",
                "org": ""
            },
            {
                "name": "peter d le roux",
                "org": ""
            },
            {
                "name": "donald w marion",
                "org": ""
            },
            {
                "name": "lawrence f marshall",
                "org": ""
            },
            {
                "name": "alex b valadka",
                "org": ""
            }
        ],
        "venue": "Neurosurgery",
        "year": 2008
    },
    "8bCMDKxZ": {
        "id": "8bCMDKxZ",
        "title": "A more precise HIV integration assay designed to detect small differences finds lower levels of integrated DNA in HAART treated patients.",
        "abstract": "Many studies report the level of total viral DNA in HIV-infected patients, but few studies report the level of integrated DNA. It is important to measure integrated DNA in HIV-infected patients because the information could shed light on the effectiveness of antiretroviral therapy, especially intensified therapy, when viral loads may remain undetectable. In order to develop an integration assay for patient samples, we enhanced the sensitivity of our prior integration assay. To do this, we exploited a technique that we developed, called repetitive sampling, and optimized reaction conditions for rare event detection, rather than large dynamic range. We also designed our primers to match more conserved regions of HIV. The result is a new, sensitive, quantitative assay that allows us to measure integrated DNA in HIV-infected patients. When we applied our integration assay to patient PBMCs, we found that the use of HAART is associated with reduced levels of integrated DNA.",
        "keywords": [
            "persistence",
            "integration",
            "latency",
            "antiretroviral therapy",
            "intensification",
            "ongoing replication",
            "haart",
            "reservoirs",
            "eradication",
            "hiv"
        ],
        "authors": [
            {
                "name": "Jianqing J Yu",
                "org": "Department of Pathology and Laboratory Medicine, Division of Transfusion Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA"
            },
            {
                "name": "Te Lang Wu",
                "org": "Department of Microbiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA"
            },
            {
                "name": "Megan K Liszewski",
                "org": "Department of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania, USA"
            },
            {
                "name": "Jihong Dai",
                "org": "Department of Pathology and Laboratory Medicine, Division of Transfusion Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA"
            },
            {
                "name": "William J Swiggard",
                "org": "Cooley Dickinson Hospital, Northampton, Massachusetts, USA"
            },
            {
                "name": "Clifford Baytop",
                "org": "Department of Pathology and Laboratory Medicine, Division of Transfusion Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA"
            },
            {
                "name": "Ian Frank",
                "org": "Department of Medicine, Division of Infectious Diseases, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA"
            },
            {
                "name": "Bruce L Levine",
                "org": "Department of Pathology and Laboratory Medicine, Division of Transfusion Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA"
            },
            {
                "name": "Wei Yang",
                "org": "Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, Pennsylvania, USA"
            },
            {
                "name": "Theodore Theodosopoulos",
                "org": "IKOS Research, UK"
            },
            {
                "name": "Una O'Doherty",
                "org": ""
            }
        ],
        "venue": "Virology",
        "year": 2008
    },
    "3b4l0ngK": {
        "id": "3b4l0ngK",
        "title": "BRAIN HYPERTHERMIA AFTER TRAUMATIC BRAIN INJURY DOES NOT REDUCE BRAIN OXYGEN: ",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Alejandro M. Spiotta",
                "org": ""
            },
            {
                "name": "Michael F. Stiefel",
                "org": ""
            },
            {
                "name": "Gregory G. Heuer",
                "org": ""
            },
            {
                "name": "Stephanie Bloom",
                "org": ""
            },
            {
                "name": "Eileen Maloney-Wilensky",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "M. Sean Grady",
                "org": ""
            },
            {
                "name": "Peter D. Le Roux",
                "org": ""
            }
        ],
        "venue": "Neurosurgery",
        "year": 2008
    },
    "00AtwXMe": {
        "id": "00AtwXMe",
        "title": "Brain oxygen tension and outcome in patients with aneurysmal subarachnoid hemorrhage. Authors' reply",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Rohan Ramakrishna",
                "org": ""
            },
            {
                "name": "Michael F. Stiefel",
                "org": ""
            },
            {
                "name": "Joshua D. Udoetuk",
                "org": ""
            },
            {
                "name": "Alejandro M. Spiotta",
                "org": ""
            },
            {
                "name": "Joshua M. Levine",
                "org": ""
            },
            {
                "name": "W. Andrew Kofke",
                "org": ""
            },
            {
                "name": "Eric L. Zager",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Peter D. Le Roux",
                "org": ""
            }
        ],
        "venue": "Journal of Neurosurgery",
        "year": 2009
    },
    "o9XRMjkU": {
        "id": "o9XRMjkU",
        "title": "Erratum: Brain oxygen tension and outcome in patients with aneurysmal subarachnoid hemorrhage",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Rohan Ramakrishna",
                "org": ""
            },
            {
                "name": "Michael Stiefel",
                "org": ""
            },
            {
                "name": "Joshua Udoetuk",
                "org": ""
            },
            {
                "name": "Alejandro Spiotta",
                "org": ""
            },
            {
                "name": "Joshua M. Levine",
                "org": ""
            },
            {
                "name": "W. Andrew Kofke",
                "org": ""
            },
            {
                "name": "Eric Zager",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Peter Le Roux",
                "org": ""
            }
        ],
        "venue": "Journal of Neurosurgery",
        "year": 2009
    },
    "cXuNBlV4": {
        "id": "cXuNBlV4",
        "title": "Brain tissue oxygen and outcome after severe traumatic brain injury: a systematic review.",
        "abstract": "In this study, available medical literature were reviewed to determine whether brain hypoxia as measured by brain tissue oxygen (Bto2) levels is associated with increased risk of poor outcome after traumatic brain injury (TBI). A secondary objective was to examine the safety profile of a direct BtO2 probe. DATA SOURCE AND EXTRACTION: Clinical studies published between 1993 and 2008 were identified from electronic databases, Index Medicus, bibliographies of pertinent articles, and expert consultation. The following inclusion criteria were applied for outcome analysis: 1) more than 10 patients described, 2) use of a direct Bto2 monitor, 3) brain hypoxia defined as Bto2 <10 mm Hg for >15 or 30 minutes, 4) 6-month outcome data, and 5) clear reporting of patient outcome associated with Bto2. For the analysis, each selected article had to have adequate data to determine odds ratios (ORs) and confidence intervals (CIs). Thirteen studies met the initial inclusion criteria and three were included in the final outcome analysis. Safety data were abstracted from any report where it was mentioned.The three studies included 150 evaluable patients with severe TBI (Glasgow Coma Scale <or=8). Brain hypoxia was identified in 71 (47%) of these patients. Among the patients with brain hypoxia, 52 (73%) had unfavorable outcome including 39 (55%) who died. In the absence of brain hypoxia, 34 (43%) patients had an unfavorable outcome, including 17 (22%) who died. Overall brain hypoxia (Bto2 <10 mm Hg >15 minutes) was associated with worse outcome (OR 4.0; 95% CI 1.9-8.2) and increased mortality (OR 4.6; 95% CI 2.2-9.6). We reviewed published safety data; in 292 patients monitored with a Bto2 probe, only two adverse events were reported.Summary results indicate that brain hypoxia (<10 mm Hg) is associated with worse outcome after severe TBI and that Bto2 probes are safe. These results imply that treating patients to increase Bto2 may improve outcome after severe TBI. This question will require further study.",
        "keywords": [
            "systematic review"
        ],
        "authors": [
            {
                "name": "Eileen Maloney-Wilensky",
                "org": ""
            },
            {
                "name": "Vicente Gracias",
                "org": ""
            },
            {
                "name": "Arthur Itkin",
                "org": ""
            },
            {
                "name": "Katherine Hoffman",
                "org": ""
            },
            {
                "name": "Stephanie Bloom",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Susan Christian",
                "org": ""
            },
            {
                "name": "Peter D LeRoux",
                "org": ""
            }
        ],
        "venue": "Critical care medicine",
        "year": 2009
    },
    "pnLUggVp": {
        "id": "pnLUggVp",
        "title": "Patient Transport and Brain Oxygen in Comatose Patients: ",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Edward W. Swanson",
                "org": ""
            },
            {
                "name": "Justin Mascitelli",
                "org": ""
            },
            {
                "name": "Michael Stiefel",
                "org": ""
            },
            {
                "name": "Eileen MacMurtrie",
                "org": ""
            },
            {
                "name": "Joshua Levine",
                "org": ""
            },
            {
                "name": "W. Andrew Kofke",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Peter D. Le Roux",
                "org": ""
            }
        ],
        "venue": "Neurosurgery",
        "year": 2010
    },
    "aDoZCohP": {
        "id": "aDoZCohP",
        "title": "Portable head CT scan and its effect on intracranial pressure, cerebral perfusion pressure, and brain oxygen: Clinical article",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "joshua m levine",
                "org": ""
            },
            {
                "name": "w andrew kofke",
                "org": ""
            },
            {
                "name": "kaitlin peace",
                "org": ""
            },
            {
                "name": "eileen maloneywilensky",
                "org": ""
            },
            {
                "name": "suzanne frangos",
                "org": ""
            },
            {
                "name": "marianne hujcs",
                "org": ""
            },
            {
                "name": "peter d le roux",
                "org": ""
            },
            {
                "name": "wei yang",
                "org": ""
            }
        ],
        "venue": "Journal of Neurosurgery",
        "year": 2010
    },
    "DGscTKxQ": {
        "id": "DGscTKxQ",
        "title": "The use of a portable head CT scanner in the intensive care unit.",
        "abstract": "Transport of critically ill intensive care unit (ICU) patients may be hazardous. In this study, we examined the use of a portable head CT scanner (CereTom) in the ICU to assess its feasibility, safety, and radiological quality. Two hundred and twenty-five portable head CT scans were obtained from 114 patients (mean age = 57 +/- 18 years) treated in a neurosurgical intensive care unit at a university-based Level I trauma center. Patient radiological and ICU records were retrospectively reviewed. The vast majority of portable CT scans were performed after an intracranial procedure (24%) due to neurological deterioration (16%) or in routine follow-up (16%). Diagnostic quality was judged to be adequate, and no scans needed to be repeated because of poor quality. No scans were complicated by accidental disconnection of an intravenous line. In ventilated patients, there were no interruptions in mechanical ventilation and no inadvertent extubations. In addition, continuous intracranial monitoring, when in use, remained connected. The average total time to perform a portable head CT scan was 19.5 +/- 3.5 min. The actual scan time was 2.5 +/- 0.7 min. These results suggest that the portable CT scanner (CereTom) is feasible, easy to use, and safe and provides adequate radiological quality for diagnostic decisions.",
        "keywords": [],
        "authors": [
            {
                "name": "Kaitlin Peace",
                "org": ""
            },
            {
                "name": "Eileen Maloney Wilensky",
                "org": ""
            },
            {
                "name": "Suzanne Frangos",
                "org": ""
            },
            {
                "name": "Eileen MacMurtrie",
                "org": ""
            },
            {
                "name": "Elizabeth Shields",
                "org": ""
            },
            {
                "name": "Marianne Hujcs",
                "org": ""
            },
            {
                "name": "Joshua Levine",
                "org": ""
            },
            {
                "name": "Andrew Kofke",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Peter D Le Roux",
                "org": ""
            }
        ],
        "venue": "The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses",
        "year": 2010
    },
    "vpxGbA4A": {
        "id": "vpxGbA4A",
        "title": "Symptoms Characteristic of Heart Failure Among CKD Patients Without Diagnosed Heart Failure",
        "abstract": "Conclusion CKD patients without diagnosed HF have a substantial burden of symptoms characteristic of HF, particularly among those with lower estimated glomerular filtration rate and hemoglobin levels.",
        "keywords": [
            "glomerular filtration rate",
            "hemoglobin",
            "cohort studies",
            "questionnaires"
        ],
        "authors": [
            {
                "name": "Michael G. Shlipak",
                "org": ""
            },
            {
                "name": "James P. Lash",
                "org": "Univeristy of Illinois, Chicago; Department of Medicine, Nephrology; Chicago, IL"
            },
            {
                "name": "Wei Yang",
                "org": "University of Pennsylvania; Center for Clinical Epidemiology and Biostatistics, Department of Biostatistics and Epidemiology: Philadelphia, PA"
            },
            {
                "name": "Valerie Teal",
                "org": "University of Pennsylvania; Center for Clinical Epidemiology and Biostatistics, Department of Biostatistics and Epidemiology: Philadelphia, PA"
            },
            {
                "name": "Martin Keane",
                "org": "University of Pennsylvania; Department of Medicine, Cardiology, Philadelphia, PA"
            },
            {
                "name": "Tom Cappola",
                "org": "University of Pennsylvania; Department of Medicine, Cardiology, Philadelphia, PA"
            },
            {
                "name": "Chris Keller",
                "org": "Boise Kidney & Hypertension Institute; Boise, ID"
            },
            {
                "name": "Kenneth Jamerson",
                "org": "University of Michigan; Department of Internal Medicine; Ann Arbor, MI"
            },
            {
                "name": "John Kusek",
                "org": "National Institute of Diabetes, Digestive and Kidney Diseases; Bethesda, MD"
            },
            {
                "name": "Patrice Delafontaine",
                "org": "Tulane University; Department of Medicine, Cardiology; New Orleans, LA"
            },
            {
                "name": "Jiang He",
                "org": "Tulane University; Department of Medicine, Cardiology; New Orleans, LA"
            },
            {
                "name": "Edgar R. Miller",
                "org": "Johns Hopkins University, School of Public Health; Department of Medicine; Baltimore, MD"
            },
            {
                "name": "Martin Schreiber",
                "org": "Cleveland Clinic, Department of Nephrology and Hypertension; Stongsville, OH"
            },
            {
                "name": "Alan S. Go",
                "org": "Kaiser Permanente of Northern California; Oakland, CA"
            }
        ],
        "venue": "Journal of Cardiac Failure",
        "year": 2011
    },
    "AFKhO3FX": {
        "id": "AFKhO3FX",
        "title": "Abstract 10820: Novel Risk Factors for Coronary Artery Calcification Among Patients with Chronic Kidney Disease: The CRIC Study",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "jiang he",
                "org": ""
            },
            {
                "name": "muredach p reilly",
                "org": ""
            },
            {
                "name": "wei yang",
                "org": ""
            },
            {
                "name": "jing chen",
                "org": ""
            },
            {
                "name": "alan s go",
                "org": ""
            },
            {
                "name": "james p lash",
                "org": ""
            },
            {
                "name": "mahboob rahman",
                "org": ""
            },
            {
                "name": "christopher r defilippi",
                "org": ""
            },
            {
                "name": "crystal a gadegbeku",
                "org": ""
            },
            {
                "name": "radhika kanthety",
                "org": ""
            },
            {
                "name": "kaixiang tao",
                "org": ""
            },
            {
                "name": "l lee hamm",
                "org": ""
            },
            {
                "name": "akinlolu o ojo",
                "org": ""
            },
            {
                "name": "raymond r townsend",
                "org": ""
            },
            {
                "name": "matthew j budoff",
                "org": ""
            }
        ],
        "venue": "Circulation",
        "year": 2011
    },
    "t9WZ6kSS": {
        "id": "t9WZ6kSS",
        "title": "Prescriber adherence to pharmacokinetic monitoring service recommendations for aminoglycoside dosing and the risk of acute kidney injury",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "l cheung",
                "org": ""
            },
            {
                "name": "brian l strom",
                "org": ""
            },
            {
                "name": "harold i feldman",
                "org": ""
            },
            {
                "name": "maximilian herlim",
                "org": ""
            },
            {
                "name": "charles e leonard",
                "org": ""
            },
            {
                "name": "a r localio",
                "org": ""
            },
            {
                "name": "aron j cohen",
                "org": ""
            },
            {
                "name": "wei yang",
                "org": ""
            },
            {
                "name": "sean hennessy",
                "org": ""
            }
        ],
        "venue": "principles and practice of constraint programming",
        "year": 2011
    },
    "XoU6Roh3": {
        "id": "XoU6Roh3",
        "title": "Relationship of Estimated GFR and Coronary Artery Calcification in the (CRIC) Chronic Renal Insufficiency Cohort Study",
        "abstract": "Conclusions We demonstrated a graded relationship between severity of CKD and CAC, independent of traditional risk factors. These findings supports recent guidelines that state that if vascular calcification is present, it should be considered as a complementary component to be included in the decision making required for individualizing treatment of CKD.",
        "keywords": [
            "cross sectional studies",
            "cohort study",
            "ethnic groups",
            "risk factors",
            "severity of illness index",
            "epidemiology",
            "calcium",
            "glomerular filtration rate",
            "odds ratio",
            "cohort studies",
            "renal function"
        ],
        "authors": [
            {
                "name": "Matthew J. Budoff",
                "org": ""
            },
            {
                "name": "Daniel J. Rader",
                "org": "Division of Cardiology, Department of Medicine, University of Pennsylvania, Pennsylvania, PA"
            },
            {
                "name": "Muredach P. Reilly",
                "org": "Division of Cardiology, Department of Medicine, University of Pennsylvania, Pennsylvania, PA"
            },
            {
                "name": "Emile R. Mohler",
                "org": "Division of Cardiology, Department of Medicine, University of Pennsylvania, Pennsylvania, PA"
            },
            {
                "name": "Jim Lash",
                "org": "University of Illinois at Chicago, IL"
            },
            {
                "name": "Wei Yang",
                "org": "Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Pennsylvania, PA"
            },
            {
                "name": "Leigh Rosen",
                "org": "Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Pennsylvania, PA"
            },
            {
                "name": "Melanie Glenn",
                "org": "Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Pennsylvania, PA"
            },
            {
                "name": "Valerie Teal",
                "org": "Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Pennsylvania, PA"
            },
            {
                "name": "Harold I. Feldman",
                "org": "Renal Electrolyte and Hypertension Division, Department of Medicine, University of Pennsylvania, Pennsylvania, PA"
            }
        ],
        "venue": "American Journal of Kidney Diseases",
        "year": 2011
    },
    "wCsM9xhU": {
        "id": "wCsM9xhU",
        "title": "Brain tissue oxygen-based therapy and outcome after severe traumatic brain injury: a systematic literature review.",
        "abstract": "Observational clinical studies demonstrate that brain hypoxia is associated with poor outcome after severe traumatic brain injury (TBI). In this study, available medical literature was reviewed to examine whether brain tissue oxygen (PbtO2)-based therapy is associated with improved patient outcome after severe TBI. Clinical studies published between 1993 and 2010 that compared PbtO2-based therapy combined with intracranial and cerebral perfusion pressure (ICP/CPP)-based therapy to ICP/CPP-based therapy alone were identified from electronic databases, Index Medicus, bibliographies of pertinent articles, and expert consultation. For analysis, each selected paper had to have adequate data to determine odds ratios (ORs) and confidence intervals (CIs) of outcome described by the Glasgow outcome score (GOS). Seven studies that compared ICP/CPP and PbtO2- to ICP/CPP-based therapy were identified. There were no randomized studies and no comparison studies in children. Four studies, published in 2003, 2009, and 2010 that included 491 evaluable patients were used in the final analysis. Among patients who received PbtO2-based therapy, 121(38.8%) had unfavorable and 191 (61.2%) had a favorable outcome. Among the patients who received ICP/CPP-based therapy 104 (58.1%) had unfavorable and 75 (41.9%) had a favorable outcome. Overall PbtO2-based therapy was associated with favorable outcome (OR 2.1; 95% CI 1.4-3.1). Summary results suggest that combined ICP/CPP- and PbtO2-based therapy is associated with better outcome after severe TBI than ICP/CPP-based therapy alone. Cross-organizational practice variances cannot be controlled for in this type of review and so we cannot answer whether PbtO2-based therapy improves outcome. However, the potentially large incremental value of PbtO2-based therapy provides justification for a randomized clinical trial.",
        "keywords": [
            "brain tissue oxygen cerebral perfusion pressure intracranial pressure icp outcome traumatic brain injury"
        ],
        "authors": [
            {
                "name": "Raj Nangunoori",
                "org": "Departments of Neurosurgery, Clinical Research Division, University of Pennsylvania, 235 S 8th Street, Philadelphia, PA 19106, USA"
            },
            {
                "name": "Eileen Maloney-Wilensky",
                "org": "Departments of Neurosurgery, Clinical Research Division, University of Pennsylvania, 235 S 8th Street, Philadelphia, PA 19106, USA"
            },
            {
                "name": "Michael Stiefel",
                "org": "Departments of Neurosurgery, Clinical Research Division, University of Pennsylvania, 235 S 8th Street, Philadelphia, PA 19106, USA"
            },
            {
                "name": "Soojin Park",
                "org": "Departments of Neurosurgery, Clinical Research Division, University of Pennsylvania, 235 S 8th Street, Philadelphia, PA 19106, USA"
            },
            {
                "name": "W Andrew Kofke",
                "org": "Departments of Neurosurgery, Clinical Research Division, University of Pennsylvania, 235 S 8th Street, Philadelphia, PA 19106, USA"
            },
            {
                "name": "Joshua M Levine",
                "org": "Departments of Neurosurgery, Clinical Research Division, University of Pennsylvania, 235 S 8th Street, Philadelphia, PA 19106, USA"
            },
            {
                "name": "Wei Yang",
                "org": "Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA, USA"
            },
            {
                "name": "Peter D Le Roux",
                "org": "Departments of Neurosurgery, Clinical Research Division, University of Pennsylvania, 235 S 8th Street, Philadelphia, PA 19106, USA"
            }
        ],
        "venue": "Neurocritical care",
        "year": 2012
    },
    "Te1S8cwu": {
        "id": "Te1S8cwu",
        "title": "Abstract 11651: Risk Factors for Congestive Heart Failure in Patients with Chronic Kidney Disease: the CRIC Study",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Jiang He",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Amanda H. Anderson",
                "org": ""
            },
            {
                "name": "Daniel L. Dries",
                "org": ""
            },
            {
                "name": "Harold I. Feldman",
                "org": ""
            },
            {
                "name": "Radhakrishna Kallem",
                "org": ""
            },
            {
                "name": "Radhika Kanthety",
                "org": ""
            },
            {
                "name": "John W. Kusek",
                "org": ""
            },
            {
                "name": "Carissa A. Mazurick",
                "org": ""
            },
            {
                "name": "Akinlolu Ojo",
                "org": ""
            },
            {
                "name": "Dominic S. Raj",
                "org": ""
            },
            {
                "name": "Mahboob Rahman",
                "org": ""
            },
            {
                "name": "Ana C. Ricardo",
                "org": ""
            },
            {
                "name": "Michael G. Shlipak",
                "org": ""
            },
            {
                "name": "Elsayed Z. Soliman",
                "org": ""
            },
            {
                "name": "Myles Wolf",
                "org": ""
            },
            {
                "name": "L. Lee Hamm",
                "org": ""
            }
        ],
        "venue": "Circulation",
        "year": 2012
    },
    "72bjKBtD": {
        "id": "72bjKBtD",
        "title": "Cardiovascular risk factors and mitral annular calcification in type 2 diabetes.",
        "abstract": "Mitral annular calcification (MAC) is a degenerative process of the mitral annulus associated with cardiac disease and stroke. Although thought to be more prevalent in type 2 diabetes (T2DM), MAC remains poorly characterized in this population, due to confounding by renal and cardiac disease. Our goal was to study the risk factors for MAC in a sample of T2DM subjects without renal and cardiac disease.The Penn Diabetes Heart Study (PDHS) is a cross-sectional study of diabetic individuals without clinical cardiovascular or renal disease. We quantified and analyzed MAC Agatston scores in baseline cardiac CTs from 1753 individuals. Logistic and tobit regression were used to assess MAC's relationship with risk factors and coronary artery calcium (CAC).MAC was present in 12.0% of subjects, with a median Agatston score of 72.3 [Interquartile range (22.2-256.9)]. Older age, female gender, Caucasian race, and longer diabetes duration were independently associated with both the presence and extent MAC even after controlling for CAC; however, hypertension, hyperlipidemia, tobacco use, CRP levels, and other comorbidities were not associated. CAC was strongly associated with MAC [OR of 4.0 (95% CI 2.4-6.6)] in multivariable models.Age, female gender, Caucasian race, and diabetes duration were associated with the presence and extent of MAC in T2DM subjects, independent of CAC, which was also strongly associated with MAC. These data suggest that additional mechanisms for MAC formation in diabetics may exist which are distinct from those related to generalized atherosclerosis and deserve further investigation.",
        "keywords": [
            "cross sectional studies",
            "risk factors",
            "diabetes"
        ],
        "authors": [
            {
                "name": "Atif N Qasim",
                "org": "University of California at San Francisco, San Francisco, CA, USA."
            },
            {
                "name": "Hashmi Rafeek",
                "org": ""
            },
            {
                "name": "Suraj P Rasania",
                "org": ""
            },
            {
                "name": "Timothy W Churchill",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Victor A Ferrari",
                "org": ""
            },
            {
                "name": "Saurabh Jha",
                "org": ""
            },
            {
                "name": "Stephen M Master",
                "org": ""
            },
            {
                "name": "Claire K Mulvey",
                "org": ""
            },
            {
                "name": "Karen Terembula",
                "org": ""
            },
            {
                "name": "christopher dailing",
                "org": ""
            },
            {
                "name": "Matthew J Budoff",
                "org": ""
            },
            {
                "name": "Steven M Kawut",
                "org": ""
            },
            {
                "name": "Muredach P Reilly",
                "org": ""
            }
        ],
        "venue": "Atherosclerosis",
        "year": 2013
    },
    "zY9mbaZv": {
        "id": "zY9mbaZv",
        "title": "Urine neutrophil gelatinase|[ndash]|associated lipocalin levels do not improve risk prediction of progressive chronic kidney disease",
        "abstract": "",
        "keywords": [
            "lipocalins",
            "nephrology",
            "risk factors",
            "prospective studies",
            "incidence",
            "predictive value of tests",
            "severity of illness index",
            "linear models",
            "urology",
            "acute phase proteins",
            "diabetes",
            "dialysis",
            "glomerular filtration rate",
            "proportional hazards models",
            "ki"
        ],
        "authors": [
            {
                "name": "kathleen d liu",
                "org": ""
            },
            {
                "name": "wei yang",
                "org": ""
            },
            {
                "name": "amanda h anderson",
                "org": ""
            },
            {
                "name": "harold i feldman",
                "org": ""
            },
            {
                "name": "sevag demirjian",
                "org": ""
            },
            {
                "name": "takayuki hamano",
                "org": ""
            },
            {
                "name": "jiang he",
                "org": ""
            },
            {
                "name": "james p lash",
                "org": ""
            },
            {
                "name": "eva lustigova",
                "org": ""
            },
            {
                "name": "sylvia e rosas",
                "org": ""
            },
            {
                "name": "michael s simonson",
                "org": ""
            },
            {
                "name": "kaixiang tao",
                "org": ""
            },
            {
                "name": "chiyuan hsu",
                "org": ""
            }
        ],
        "venue": "Kidney International",
        "year": 2013
    },
    "owDISFdn": {
        "id": "owDISFdn",
        "title": "Serum Aldosterone and Death, End-Stage Renal Disease, and Cardiovascular Events in Blacks and WhitesNovelty and Significance",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Rajat Deo",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Abigail May Khan",
                "org": ""
            },
            {
                "name": "Nisha Bansal",
                "org": ""
            },
            {
                "name": "Xiaoming Zhang",
                "org": ""
            },
            {
                "name": "Mary B. Leonard",
                "org": ""
            },
            {
                "name": "Martin G. Keane",
                "org": ""
            },
            {
                "name": "Elsayed Z. Soliman",
                "org": ""
            },
            {
                "name": "Susan Steigerwalt",
                "org": ""
            },
            {
                "name": "Raymond R. Townsend",
                "org": ""
            },
            {
                "name": "Michael G. Shlipak",
                "org": ""
            },
            {
                "name": "Harold I. Feldman",
                "org": ""
            }
        ],
        "venue": "Hypertension",
        "year": 2014
    },
    "V0QeeItK": {
        "id": "V0QeeItK",
        "title": "Serum Aldosterone and Death, End-Stage Renal Disease, and Cardiovascular Events in Blacks and WhitesNovelty and Significance: Findings From the Chronic Renal Insufficiency Cohort (CRIC) Study",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Rajat Deo",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Abigail May Khan",
                "org": ""
            },
            {
                "name": "Nisha Bansal",
                "org": ""
            },
            {
                "name": "Xiaoming Zhang",
                "org": ""
            },
            {
                "name": "Mary B. Leonard",
                "org": ""
            },
            {
                "name": "Martin G. Keane",
                "org": ""
            },
            {
                "name": "Elsayed Z. Soliman",
                "org": ""
            },
            {
                "name": "Susan Steigerwalt",
                "org": ""
            },
            {
                "name": "Raymond R. Townsend",
                "org": ""
            },
            {
                "name": "Michael G. Shlipak",
                "org": ""
            },
            {
                "name": "Harold I. Feldman",
                "org": ""
            }
        ],
        "venue": "Hypertension",
        "year": 2014
    },
    "aDyJE7Hd": {
        "id": "aDyJE7Hd",
        "title": "SERUM ALDOSTERONE AND DEATH, END STAGE RENAL DISEASE AND CARDIOVASCULAR EVENTS IN BLACKS AND WHITES: FINDINGS FROM THE CRIC STUDY",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Rajat Deo",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Abigail May Khan",
                "org": ""
            },
            {
                "name": "Nisha Bansal",
                "org": ""
            },
            {
                "name": "Xiaoming Zhang",
                "org": ""
            },
            {
                "name": "Mary B. Leonard",
                "org": ""
            },
            {
                "name": "Martin G. Keane",
                "org": ""
            },
            {
                "name": "Elsayed Z. Soliman",
                "org": ""
            },
            {
                "name": "Susan Steigerwalt",
                "org": ""
            },
            {
                "name": "Raymond R. Townsend",
                "org": ""
            },
            {
                "name": "Michael G. Shlipak",
                "org": ""
            },
            {
                "name": "Harold I. Feldman",
                "org": ""
            }
        ],
        "venue": "Hypertension",
        "year": 2014
    },
    "eTENyx8Z": {
        "id": "eTENyx8Z",
        "title": "Serum Aldosterone and Death, End-Stage Renal Disease, and Cardiovascular Events in Blacks and Whites",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Rajat Deo",
                "org": "Division of Cardiovascular Medicine"
            },
            {
                "name": "Wei Yang",
                "org": "Perelman School of Medicine"
            },
            {
                "name": "Abigail May Khan",
                "org": "Division of Cardiovascular Medicine"
            },
            {
                "name": "Nisha Bansal",
                "org": "University of Washington"
            },
            {
                "name": "Xiaoming Zhang",
                "org": "Perelman School of Medicine"
            },
            {
                "name": "Mary B. Leonard",
                "org": "University of Pennsylvania"
            },
            {
                "name": "Martin G. Keane",
                "org": "Temple University"
            },
            {
                "name": "Elsayed Z. Soliman",
                "org": "Wake Forest University"
            },
            {
                "name": "Susan Steigerwalt",
                "org": "St. John Hospital and Medical Center"
            },
            {
                "name": "Raymond R. Townsend",
                "org": "Perelman School of Medicine"
            },
            {
                "name": "Michael G. Shlipak",
                "org": "VA Medical Center"
            },
            {
                "name": "Harold I. Feldman",
                "org": "Perelman School of Medicine"
            }
        ],
        "venue": "Hypertension",
        "year": 2014
    },
    "RTsnNFTe": {
        "id": "RTsnNFTe",
        "title": "Race modifies the association between adiposity and inflammation in patients with chronic kidney disease: findings from the CRIC study",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Maria R. Wing",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Valerie Teal",
                "org": ""
            },
            {
                "name": "Sankar D. Navaneethan",
                "org": ""
            },
            {
                "name": "Kaixiang Tao",
                "org": ""
            },
            {
                "name": "Akinlolu Ojo",
                "org": ""
            },
            {
                "name": "Nicolas N. Guzman",
                "org": ""
            },
            {
                "name": "Muredach P. Reilly",
                "org": ""
            },
            {
                "name": "Melanie Wolman",
                "org": ""
            },
            {
                "name": "Sylvia E. Rosas",
                "org": ""
            },
            {
                "name": "Magda Cuevas",
                "org": ""
            },
            {
                "name": "Michael J. Fischer",
                "org": ""
            },
            {
                "name": "Eva Lustigova",
                "org": ""
            },
            {
                "name": "Stephen R. Master",
                "org": ""
            },
            {
                "name": "Dawei Xie",
                "org": ""
            },
            {
                "name": "Dina Appleby",
                "org": ""
            },
            {
                "name": "Marshall M. Joffe",
                "org": ""
            },
            {
                "name": "John W. Kusek",
                "org": ""
            },
            {
                "name": "Harold I. Feldman",
                "org": ""
            },
            {
                "name": "Dominic S. Raj",
                "org": ""
            }
        ],
        "venue": "Obesity",
        "year": 2014
    },
    "z8OzKvHZ": {
        "id": "z8OzKvHZ",
        "title": "Kansas City Cardiomyopathy Questionnaire Score Is Associated With Incident Heart Failure Hospitalization in Patients With Chronic Kidney Disease Without Previously Diagnosed Heart Failure",
        "abstract": "Background—Chronic kidney disease is a risk factor for heart failure (HF). Patients with chronic kidney disease without diagnosed HF have an increased burden of symptoms characteristic of HF. It is not known whether these symptoms are associated with occurrence of new onset HF. Methods and Results—We studied the association of a modified Kansas City Cardiomyopathy Questionnaire with newly identified cases of hospitalized HF among 3093 participants enrolled in the Chronic Renal Insufficiency Cohort (CRIC) Study who did not report HF at baseline. The annually updated Kansas City Cardiomyopathy Questionnaire score was categorized into quartiles (Q1–4) with the lower scores representing the worse symptoms. Multivariable-adjusted repeated measure logistic regression models were adjusted for demographic characteristics, clinical risk factors for HF, N-terminal probrain natriuretic peptide level and left ventricular hypertrophy, left ventricular systolic and diastolic dysfunction. Over a mean (±SD) follow-up per...",
        "keywords": "",
        "authors": [
            {
                "name": "Rakesh K. Mishra",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": "Department of Biostatistics and Epidemiology"
            },
            {
                "name": "Jason Roy",
                "org": "Department of Biostatistics and Epidemiology"
            },
            {
                "name": "Amanda H. Anderson",
                "org": "Department of Biostatistics and Epidemiology"
            },
            {
                "name": "Nisha Bansal",
                "org": "University of Washington"
            },
            {
                "name": "Jing Chen",
                "org": "Departments of Nephrology and Hypertension"
            },
            {
                "name": "Christopher R. deFilippi",
                "org": "University of Maryland"
            },
            {
                "name": "Patrice Delafontaine",
                "org": "Tulane University"
            },
            {
                "name": "Harold I. Feldman",
                "org": "Department of Biostatistics and Epidemiology"
            },
            {
                "name": "Radhakrishna Kallem",
                "org": "University of Pennsylvania"
            },
            {
                "name": "John W. Kusek",
                "org": "National Institutes of Health"
            },
            {
                "name": "Claudia M. Lora",
                "org": "University of Illinois at Urbana-Champaign"
            },
            {
                "name": "Sylvia E. Rosas",
                "org": "Harvard University"
            },
            {
                "name": "Alan S. Go",
                "org": "Kaiser Permanente"
            },
            {
                "name": "Michael G. Shlipak",
                "org": "VA Medical Center"
            }
        ],
        "venue": "Circulation-heart Failure",
        "year": 2015
    },
    "vBoOITS4": {
        "id": "vBoOITS4",
        "title": "Inflammation and Progression of CKD: The CRIC Study.",
        "abstract": "Elevated plasma levels of fibrinogen and TNF-α and decreased serum albumin are associated with rapid loss of kidney function in patients with CKD.",
        "keywords": [
            "C-Reactive Protein",
            "Follow-Up Studies",
            "Humans",
            "Inflammation",
            "Interleukin-6",
            "Renal Insufficiency",
            "Chronic",
            "Tumor Necrosis Factor-alpha",
            "albuminuria",
            "chronic kidney disease",
            "cytokines",
            "end-stage renal disease",
            "glomerular filtration rate"
        ],
        "authors": [
            {
                "name": "Richard L Amdur",
                "org": "Due to the number of contributing authors, the affiliations are provided in the Supplemental Material."
            },
            {
                "name": "Harold I Feldman",
                "org": "Due to the number of contributing authors, the affiliations are provided in the Supplemental Material."
            },
            {
                "name": "Jayanta Gupta",
                "org": "Due to the number of contributing authors, the affiliations are provided in the Supplemental Material."
            },
            {
                "name": "Wei Yang",
                "org": "Due to the number of contributing authors, the affiliations are provided in the Supplemental Material."
            },
            {
                "name": "Peter Kanetsky",
                "org": "Due to the number of contributing authors, the affiliations are provided in the Supplemental Material."
            },
            {
                "name": "Michael Shlipak",
                "org": "Due to the number of contributing authors, the affiliations are provided in the Supplemental Material."
            },
            {
                "name": "Mahboob Rahman",
                "org": "Due to the number of contributing authors, the affiliations are provided in the Supplemental Material."
            },
            {
                "name": "James P Lash",
                "org": "Due to the number of contributing authors, the affiliations are provided in the Supplemental Material."
            },
            {
                "name": "Raymond R Townsend",
                "org": "Due to the number of contributing authors, the affiliations are provided in the Supplemental Material."
            },
            {
                "name": "Akinlolu Ojo",
                "org": "Due to the number of contributing authors, the affiliations are provided in the Supplemental Material."
            },
            {
                "name": "Akshay Roy-Chaudhury",
                "org": "Due to the number of contributing authors, the affiliations are provided in the Supplemental Material."
            },
            {
                "name": "Alan S Go",
                "org": "Due to the number of contributing authors, the affiliations are provided in the Supplemental Material."
            },
            {
                "name": "Marshall Joffe",
                "org": "Due to the number of contributing authors, the affiliations are provided in the Supplemental Material."
            },
            {
                "name": "Jiang He",
                "org": "Due to the number of contributing authors, the affiliations are provided in the Supplemental Material."
            },
            {
                "name": "Vaidyanathapuram S Balakrishnan",
                "org": "Due to the number of contributing authors, the affiliations are provided in the Supplemental Material."
            },
            {
                "name": "Paul L Kimmel",
                "org": "Due to the number of contributing authors, the affiliations are provided in the Supplemental Material."
            },
            {
                "name": "John W Kusek",
                "org": "Due to the number of contributing authors, the affiliations are provided in the Supplemental Material."
            },
            {
                "name": "Dominic S Raj",
                "org": "Due to the number of contributing authors, the affiliations are provided in the Supplemental Material. draj@mfa.gwu.edu."
            },
            {
                "name": "",
                "org": ""
            }
        ],
        "venue": "Clinical journal of the American Society of Nephrology : CJASN",
        "year": 2016
    },
    "vL0eAihZ": {
        "id": "vL0eAihZ",
        "title": "Lipidomic Signature of Progression of Chronic Kidney Disease in the Chronic Renal Insufficiency Cohort.",
        "abstract": "We conclude that a distinct panel of lipids may improve prediction of progression of CKD beyond eGFR and UPCR when added to the base model.",
        "keywords": [
            "Chronic Kidney Disease",
            "Lipids",
            "proteinuria"
        ],
        "authors": [
            {
                "name": "Farsad Afshinnia",
                "org": "Division of Nephrology Department of Internal Medicine, University of Michigan."
            },
            {
                "name": "Thekkelnaycke M Rajendiran",
                "org": "Michigan Regional Comprehensive Metabolomics Resource Core."
            },
            {
                "name": "Alla Karnovsky",
                "org": "Michigan Regional Comprehensive Metabolomics Resource Core."
            },
            {
                "name": "Tanu Soni",
                "org": "Michigan Regional Comprehensive Metabolomics Resource Core."
            },
            {
                "name": "Xue Wang",
                "org": "Department of Biostatistics and Epidemiology, University of Pennsylvania."
            },
            {
                "name": "Dawei Xie",
                "org": "Department of Biostatistics and Epidemiology, University of Pennsylvania."
            },
            {
                "name": "Wei Yang",
                "org": "Department of Biostatistics and Epidemiology, University of Pennsylvania."
            },
            {
                "name": "Tariq Shafi",
                "org": "Johns Hopkins University School of Medicine."
            },
            {
                "name": "Matthew R Weir",
                "org": "Division of Nephrology, Department of Medicine, University of Maryland School of Medicine."
            },
            {
                "name": "Jiang He",
                "org": "Tulane University School of Medicine."
            },
            {
                "name": "Carolyn S Brecklin",
                "org": "University of Illinois at Chicago."
            },
            {
                "name": "Eugene P Rhee",
                "org": "Massachusetts General Hospital."
            },
            {
                "name": "Jeffrey R Schelling",
                "org": "Case Western Reserve University, MetroHealth Medical Center."
            },
            {
                "name": "Akinlolu Ojo",
                "org": "Division of Nephrology Department of Internal Medicine, University of Michigan."
            },
            {
                "name": "Harold Feldman",
                "org": "Department of Biostatistics and Epidemiology, University of Pennsylvania."
            },
            {
                "name": "George Michailidis",
                "org": "Department of Statistics, University of Michigan."
            },
            {
                "name": "Subramaniam Pennathur",
                "org": "Michigan Regional Comprehensive Metabolomics Resource Core."
            }
        ],
        "venue": "Kidney international reports",
        "year": 2016
    },
    "FKRXzw09": {
        "id": "FKRXzw09",
        "title": "Inflammation and Arterial Stiffness in Chronic Kidney Disease: Findings From the CRIC Study.",
        "abstract": "In a large cohort of CKD participants, we observed multiple significant correlations between initial markers of inflammation and metrics of arterial stiffness, but baseline inflammation did not predict changes in arterial stiffness over time. While well-described biologic mechanisms provide the basis for our understanding of the cross-sectional results, continued efforts to design longitudinal studies are necessary to fully elucidate the relationship between chronic inflammation and arterial stiffening.",
        "keywords": [
            "arterial stiffness",
            "blood pressure",
            "chronic kidney disease",
            "hypertension",
            "inflammation"
        ],
        "authors": [
            {
                "name": "Eliot Peyster",
                "org": "Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA."
            },
            {
                "name": "Jing Chen",
                "org": "Tulane University Schools of Medicine and Public Health and Tropical Medicine, New Orleans, Louisiana, USA."
            },
            {
                "name": "Harold I Feldman",
                "org": "Center for Clinical Epidemiology & Biostatistics, University of Pennsylvania, Philadelphia, Pennsylvania, USA."
            },
            {
                "name": "Alan S Go",
                "org": "Division of Research, Kaiser Permanente of Northern California, Oakland, California, USA."
            },
            {
                "name": "Jayanta Gupta",
                "org": "Department of Health Sciences, College of Health Professions and Social Work, Florida Gulf Coast University, Fort Myers, Florida, USA."
            },
            {
                "name": "Nandita Mitra",
                "org": "Center for Clinical Epidemiology & Biostatistics, University of Pennsylvania, Philadelphia, Pennsylvania, USA."
            },
            {
                "name": "Qiang Pan",
                "org": "Center for Clinical Epidemiology & Biostatistics, University of Pennsylvania, Philadelphia, Pennsylvania, USA."
            },
            {
                "name": "Anna Porter",
                "org": "Department of Medicine, University of Illinois, Chicago, Illinois, USA."
            },
            {
                "name": "Mahboob Rahman",
                "org": "Division of Nephrology and Hypertension, Case Western Reserve University, University Hospitals Case Medical Center, Louis Stokes Cleveland VA Medical Center, Cleveland, Ohio, USA."
            },
            {
                "name": "Dominic Raj",
                "org": "Division of Renal Diseases & Hypertension, MFA-George Washington University, Washington, DC, USA."
            },
            {
                "name": "Muredach Reilly",
                "org": "Irving Institute for Clinical and Translational Research, Columbia University, New York, New York, USA."
            },
            {
                "name": "Maria R Wing",
                "org": "Division of Nephrology and Hypertension, Case Western Reserve University, University Hospitals Case Medical Center, Louis Stokes Cleveland VA Medical Center, Cleveland, Ohio, USA."
            },
            {
                "name": "Wei Yang",
                "org": "Center for Clinical Epidemiology & Biostatistics, University of Pennsylvania, Philadelphia, Pennsylvania, USA."
            },
            {
                "name": "Raymond R Townsend",
                "org": "Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA."
            },
            {
                "name": "",
                "org": ""
            }
        ],
        "venue": "American journal of hypertension",
        "year": 2017
    },
    "kTpopnbo": {
        "id": "kTpopnbo",
        "title": "Acid Load and Phosphorus Homeostasis in CKD.",
        "abstract": "The kidneys maintain acid-base homeostasis through excretion of acid as either ammonium or as titratable acids that primarily use phosphate as a buffer. In chronic kidney disease (CKD), ammoniagenesis is impaired, promoting metabolic acidosis. Metabolic acidosis stimulates phosphaturic hormones, parathyroid hormone (PTH) and fibroblast growth factor 23 (FGF-23) in vitro, possibly to increase urine titratable acid buffers, but this has not been confirmed in humans. We hypothesized that higher acid load and acidosis would associate with altered phosphorus homeostasis, including higher urinary phosphorus excretion and serum PTH and FGF-23.Cross-sectional.980 participants with CKD enrolled in the Chronic Renal Insufficiency Cohort (CRIC) Study.Net acid excretion as measured in 24-hour urine, potential renal acid load (PRAL) estimated from food frequency questionnaire responses, and serum bicarbonate concentration < 22 mEq/L.24-hour urine phosphorus and calcium excretion and serum phosphorus, FGF-23, and PTH concentrations.Using linear and log-linear regression adjusted for demographics, kidney function, comorbid conditions, body mass index, diuretic use, and 24-hour urine creatinine excretion, we found that 24-hour urine phosphorus excretion was higher at higher net acid excretion, higher PRAL, and lower serum bicarbonate concentration (each P<0.05). Serum phosphorus concentration was also higher with higher net acid excretion and lower serum bicarbonate concentration (each P=0.001). Only higher net acid excretion associated with higher 24-hour urine calcium excretion (P<0.001). Neither net acid excretion nor PRAL was associated with FGF-23 or PTH concentrations. PTH, but not FGF-23, concentration (P=0.2) was 26% (95% CI, 13%-40%) higher in participants with a serum bicarbonate concentration <22 versus ≥22 mEq/L (P<0.001). Primary results were similar if stratified by estimated glomerular filtration rate categories or adjusted for iothalamate glomerular filtration rate (n=359), total energy intake, dietary phosphorus, or urine urea nitrogen excretion, when available.Possible residual confounding by kidney function or nutrition; urine phosphorus excretion was included in calculation of the titratable acid component of net acid excretion.In CKD, higher acid load and acidosis associate independently with increased circulating phosphorus concentration and augmented phosphaturia, but not consistently with FGF-23 or PTH concentrations. This may be an adaptation that increases titratable acid excretion and thus helps maintain acid-base homeostasis in CKD. Understanding whether administration of base can lower phosphorus concentrations requires testing in interventional trials.",
        "keywords": [
            "Acid-base",
            "FE(Pi)",
            "acid load",
            "acidosis",
            "chronic kidney disease (CKD)",
            "fibroblast growth factor 23 (FGF-23)",
            "parathyroid hormone (PTH)",
            "phosphaturic hormones",
            "phosphorus",
            "phosphorus excretion",
            "phosphorus homeostasis",
            "physiology",
            "potential renal acid load (PRAL)"
        ],
        "authors": [
            {
                "name": "Khairallah Pascale",
                "org": "Department of Medicine, Duke University School of Medicine, Durham, NC."
            },
            {
                "name": "Isakova Tamara",
                "org": "Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL; Center for Translational Metabolism and Health, Institute of Public Health and Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL."
            },
            {
                "name": "Asplin John",
                "org": "Litholink Corp, Laboratory Corporation of America Holdings, Chicago, IL."
            },
            {
                "name": "Hamm Lee",
                "org": "Department of Medicine, Tulane University School of Medicine, New Orleans, LA."
            },
            {
                "name": "Dobre Mirela",
                "org": "Department of Medicine, Case Western Reserve University, Cleveland, OH."
            },
            {
                "name": "Rahman Mahboob",
                "org": "Department of Medicine, Case Western Reserve University, Cleveland, OH."
            },
            {
                "name": "Sharma Kumar",
                "org": "Department of Medicine, University of San Diego, San Diego, CA."
            },
            {
                "name": "Leonard Mary",
                "org": "Department of Pediatrics, Stanford University School of Medicine, Palo Alto, CA."
            },
            {
                "name": "Miller Edgar",
                "org": "Department of Medicine, Prevention and Clinical Research, Johns Hopkins University, Baltimore, MD; Welch Center for Epidemiology, Prevention and Clinical Research, Johns Hopkins University, Baltimore, MD."
            },
            {
                "name": "Jaar Bernard",
                "org": "Department of Medicine, Prevention and Clinical Research, Johns Hopkins University, Baltimore, MD; Welch Center for Epidemiology, Prevention and Clinical Research, Johns Hopkins University, Baltimore, MD; Nephrology Center of Maryland, Baltimore, MD."
            },
            {
                "name": "Brecklin Carolyn",
                "org": "Department of Medicine, University of Illinois at Chicago, Chicago, IL."
            },
            {
                "name": "Yang Wei",
                "org": "Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA."
            },
            {
                "name": "Wang Xue",
                "org": "Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA."
            },
            {
                "name": "Feldman Harold",
                "org": "Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA; Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA."
            },
            {
                "name": "Wolf Myles",
                "org": "Department of Medicine, Duke University School of Medicine, Durham, NC."
            },
            {
                "name": "Scialla Julia J",
                "org": "Department of Medicine, Duke University School of Medicine, Durham, NC; Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC; Department of Medicine, Durham Veterans Affairs Medical Center, Durham, NC."
            },
            {
                "name": "null null",
                "org": ""
            }
        ],
        "venue": "American journal of kidney diseases : the official journal of the National Kidney Foundation",
        "year": 2017
    },
    "bNUWZ1FF": {
        "id": "bNUWZ1FF",
        "title": "Joint Modeling of Repeated Measures and Competing Failure Events In a Study of Chronic Kidney Disease.",
        "abstract": "We are motivated by the Chronic Renal Insufficiency Cohort (CRIC) study to identify risk factors for renal progression in patients with chronic kidney diseases. The CRIC study collects two types of renal outcomes: glomerular filtration rate (GFR) estimated annually and end stage renal disease (ESRD). A related outcome of interest is death which is a competing event for ESRD. A joint modeling approach is proposed to model a longitudinal outcome and two competing survival outcomes. We assume multivariate normality on the joint distribution of the longitudinal and survival outcomes. Specifically, a mixed effects model is fit on the longitudinal outcome and a linear model is fit on each survival outcome. The three models are linked together by having the random terms of the mixed effects model as covariates in the survival models. EM algorithm is used to estimate the model parameters and the non-parametric bootstrap is used for variance estimation. A simulation study is designed to compare the proposed method with an approach that models the outcomes sequentially in two steps. We fit the proposed model to the CRIC data and show that the protein-to-creatinine ratio is strongly predictive of both estimated GFR and ESRD but not death.",
        "keywords": [
            "Chronic kidney disease",
            "Competing risk",
            "Informative dropout",
            "Joint modeling",
            "Multivariate normality"
        ],
        "authors": [
            {
                "name": "Wei Yang",
                "org": "Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine."
            },
            {
                "name": "Dawei Xie",
                "org": "Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine."
            },
            {
                "name": "Qiang Pan",
                "org": "Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine."
            },
            {
                "name": "Harold I Feldman",
                "org": "Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine."
            },
            {
                "name": "Wensheng Guo",
                "org": "Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine."
            }
        ],
        "venue": "Statistics in biosciences",
        "year": 2017
    },
    "MKLPoTFH": {
        "id": "MKLPoTFH",
        "title": "Spin-filtering effect and proximity effect in normal metal/ferromagnetic insulator/normal metal/superconductor junctions",
        "abstract": "Taking into account the thickness of the ferromagnetic insulator (FI), the spin-filtering effect and proximity effect in normal metal/ferromagnetic insulator/normal metal/superconductor (NM/FI/NM/SC) junctions are studied based on an extended Blonder–Tinkham–Klapwijk (BTK) theory. It is shown that a spin-dependent energy shift during the tunneling process induces splitting of the sub-energy gap conductance peaks and the spin polarization in the ferromagnetic insulator causes an imbalance of the peak heights. Different from the ferromagnet the spin-filtering effect of the FI cannot cause the reversion of the normalized conductance in NM/FI/NM/SC junctions.",
        "keywords": [
            "proximity effect",
            "nm/fi/nm/sc junction",
            "spin-filtering effect",
            "74.50.+r",
            "energy gap",
            "spin polarization"
        ],
        "authors": [
            {
                "name": "Hong Li",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": "College of Physics Science and Technology, China University of Petroleum, Dongying 257061, China"
            },
            {
                "name": "Xinjian Yang",
                "org": "College of Chemistry and Chemical Engineering, China University of Petroleum, Dongying 257061, China"
            },
            {
                "name": "Minghui Qin",
                "org": "College of Physics Science and Technology, China University of Petroleum, Dongying 257061, China"
            },
            {
                "name": "Yihong Xu",
                "org": "Shandong Institute of Trade Union's Administration Cadres, Jinnan 250100, China"
            }
        ],
        "venue": "Journal of Magnetism and Magnetic Materials",
        "year": 2007
    },
    "ghRG2gBi": {
        "id": "ghRG2gBi",
        "title": "Effects of normal metal layer on differential conductance in superconductor tunnel junctions",
        "abstract": "Using Bogoliubov-de Gennes (BdG) equation and Blonder-Tinkham-Klapwijk (BTK) model and Considering the thickness of the insulator, the quasi-particle transport coefficients and the differential conductance in ferromagnet/insulator/normal metal/s-wave superconductor (FINS) tunnel junctions were calculated. The results show that the differential conductance takes periodic oscillation with the change of normal metal layer thickness, and the oscillation period depends strongly on the bias voltage. The normalized conductance shows superconducting and ferromagnetic feature in a thin normal metal layer induced by the proximity effect.",
        "keywords": [
            "Differential conductance",
            "Exchange energy",
            "Ferromagnet/insulator/normal metal/s-wave superconductor tunnel junctions",
            "Proximity effect",
            "Square-potential barrier"
        ],
        "authors": [
            {
                "name": "Hong Li",
                "org": "China University of Petroleum - Beijing(China University of Petroleum,University of Petroleum),Beijing,China"
            },
            {
                "name": "Wei Yang",
                "org": "China University of Petroleum - Beijing(China University of Petroleum,University of Petroleum),Beijing,China"
            },
            {
                "name": "YANG Xin-jian",
                "org": "China University of Petroleum - Beijing(China University of Petroleum,University of Petroleum),Beijing,China"
            },
            {
                "name": "QIN Ming-hui",
                "org": "China University of Petroleum - Beijing(China University of Petroleum,University of Petroleum),Beijing,China"
            },
            {
                "name": "XU Yi-hong",
                "org": "Shandong Institute of Trade Union's Administration Cadres(Shandong Institute of Trade Union's Administration Cadres,Shandong Institute of Trade Unions' Administration Cadres,ShanDong Institute of Trade Union's Administration Cadres,Shandong Institute of Trade Unions' Administration Cadre),Jinan,China"
            }
        ],
        "venue": "Zhongguo Shiyou Daxue Xuebao (Ziran Kexue Ban)/Journal of China University of Petroleum (Edition of Natural Science)",
        "year": 2007
    },
    "BIEIDnR1": {
        "id": "BIEIDnR1",
        "title": "Proximity effect in normal metal/ferromagnet/d-wave superconductor structures",
        "abstract": "The superconducting proximity effect in normal metal/insulator/ferromagnet/d-wave superconductor (N/I/F/D) structures is studied based on an extended Blonder–Tinkham–Klapwijk (BTK) theory. The transition from the “0” to “π” state is found in the conductance spectra with increasing thickness of F or the ferromagnetic exchange energy. The superconducting proximity effect is drastically changed by the orientation angle α , as α increases the proximity effect is enhanced, being strongest for α / π = 0.25. PACS 74.50.+r Keywords Proximity effect N/I/F/D structures",
        "keywords": [
            "n/i/f/d structures",
            "proximity effect",
            "superconductors"
        ],
        "authors": [
            {
                "name": "Hong Li",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": "College of Physics Science and Technology, China University of Petroleum, Dongying 257061, China"
            },
            {
                "name": "Xinjian Yang",
                "org": "College of Chemistry and Chemical Engineering, China University of Petroleum, Dongying 257061, China"
            },
            {
                "name": "Minghui Qin",
                "org": "College of Physics Science and Technology, China University of Petroleum, Dongying 257061, China"
            },
            {
                "name": "Yihong Xu",
                "org": "Shandong Institute of Trade Union’s Administration Cadres, Jinnan 250100, China"
            }
        ],
        "venue": "Physica C: Superconductivity and its applications",
        "year": 2007
    },
    "XwMVSQQT": {
        "id": "XwMVSQQT",
        "title": "'In-line attack' conformational effect plays a modest role in an enzyme-catalyzed RNA cleavage: a free energy simulation study.",
        "abstract": "Since the proposal of 'in-line attack' conformation as a possibly important intermediate in RNA cleavage, its structure has been captured in various protein and RNA enzymes; these structures strengthen the belief that this conformation plays an essential role in the catalysis of RNA cleavage. As generally discussed, this intermediate structure can be involved in energy barrier reduction in two possible ways, e.g. through either conformational effect or electrostatic effect. In order to quantitatively elucidate the contribution of conformational effect in this type of enzyme catalysis, free energy simulations were performed on the RNA structures both in a splicing endonuclease complex and in the aqueous solution. Our free energy simulation results revealed that the 'in-line attack' conformational effect plays a modest role in facilitating the reaction rate enhancement (approximately 12-fold) compared with the overall 10(12)-fold rate increase. The close agreement between the present computational estimation and an experimental measurement on the spontaneous RNA cleavage in an in vitro evolved ATP aptamer motives us to realize that the conformation distribution of an enzyme substrate prior to rather than after its binding determines the upper bound of the rate enhancement ability through the conformational strategy.",
        "keywords": [
            "upper bound",
            "free energy",
            "enzyme",
            "rna",
            "static electricity",
            "reaction rate",
            "rna structure",
            "computational biology",
            "enzyme catalysis",
            "computer simulation",
            "catalysis",
            "aqueous solution"
        ],
        "authors": [
            {
                "name": "Donghong Min",
                "org": ""
            },
            {
                "name": "Song Xue",
                "org": ""
            },
            {
                "name": "Hong Li",
                "org": ""
            },
            {
                "name": "Wei Yang",
                "org": ""
            }
        ],
        "venue": "Nucleic acids research",
        "yea